Galvus meth: ndemanga za anthu odwala matenda ashuga, malangizo ogwiritsira ntchito

Mankhwala omwe Galal adakumana nawo adapangidwira kuti athandizire komanso kupumula kwa matenda a shuga mellitus a fomu yodziyimira payekha. Mankhwala amakono apanga mitundu yambiri ya mankhwala osiyanasiyana a magulu osiyanasiyana ndi makalasi.

Ndi mankhwala ati omwe angagwiritse ntchito komanso zomwe zili bwino kwa odwala omwe ali ndi vutoli kuti alepheretse matenda komanso kuletsa zovuta zoyipa zomwe zimatsimikizidwa ndi dotolo yemwe akutsogolera matenda.

Mankhwala amakono amagwiritsa ntchito mitundu ingapo yamankhwala kuti achepetse kuchuluka kwa glucose ndikukhalitsa kagayidwe kazakudya mthupi.

Mankhwala aliwonse ayenera kuperekedwa ndi katswiri wazachipatala.

Pankhaniyi, kudzichitira nokha kapena kusintha kwa mankhwalawa, mlingo wake umaletsedwa mwamphamvu, chifukwa zingayambitse mavuto.

Polimbana ndi matenda a zam'mimba, muyenera kukumbukira kuti kumwa mankhwala kuyenera kutsagana ndi kuwunika konsekonse wamagulu a shuga m'magazi.

Mpaka pano, chithandizo cha matenda a shuga 2 ndi kugwiritsa ntchito imodzi mwa magulu otsatirawa a zida zamankhwala:

Mankhwala omwe amachokera ku sulfonylurea. The pharmacological tingati kulimbikitsa katulutsidwe wa amkati insulin. Ammonyl ndi Diabetes ndi ena mwa mankhwala omwe amapangidwa pamaziko a sulfonylurea.
Zogulitsa kuchokera ku gulu la Biguanide. Zotsatira zawo cholinga chake ndikuchepetsa kufunika kwa insulin katulutsidwe. Omwe amayimira mankhwalawa pachakudya chonsechi ndi kukonzekera ndi njira yayikulu yogwiritsira ntchito mankhwala a metformin hydrochloride (Glucofage).
Mankhwala omwe amachokera ku thiazolidinol amathandizira kuchepetsa shuga m'magazi ndipo amathandizanso kusintha kwa mawonekedwe a lipid. Mankhwala oterewa m'magazi awo ndi ofanana ndi Biguanides.
Meglitinides amathandizira kuti amasulidwe a insulin ambiri komanso kuwonjezeka kwa shuga m'magazi. Ubwino waukulu wa mankhwalawa ndikuti amakulolani kusintha shuga yokhala ndi shuga yachilendo.
Alfa glucosidase zoletsa. Zotsatira zazikulu zamankhwala zotere zimapangidwa kuti zilepheretse mayamwidwe ovuta, chifukwa chake glucose amalowa m'magazi ochepa kwambiri.
Amayamwa.
Zinthu zophatikiza zamankhwala, zomwe zimaphatikizapo zigawo zikuluzikulu zingapo kuchokera m'magulu omwe ali pamwambawa.

Mankhwala omwe amasankhidwa kuti alandire chithandizo ayenera kumwedwa pamankhwala omwe dokotala amafotokozera.

Kuphatikiza apo, momwe wodwalayo alili, kuchuluka kwa zochitika zolimbitsa thupi, kulemera kwa thupi kuyenera kukumbukiridwa.

Kodi mankhwala a hypoglycemic ndi ati?

Mankhwala a Galvus omwe adakumana nawo ndi hypoglycemic mankhwala opaka pakamwa. Zigawo zikuluzikulu zogwiritsa ntchito mankhwalawa ndi zinthu ziwiri - vildagliptin ndi metformin hydrochloride

Vildagliptin ndi nthumwi ya kalasi ya zopititsa muyeso ya zida zam'mapapo. Gawoli limathandizira chidwi cha maselo a beta kuti ilowe shuga momwe iwonongera. Tiyenera kudziwa kuti pamene zinthu zoterezi zimatengedwa ndi munthu wathanzi, palibe kusintha kwa shuga m'magazi.

Metformin hydrochloride ndi woimira gulu lachitatu-greatuanide gulu, lomwe limathandizira kuletsa kwa gluconeogeneis. Kugwiritsa ntchito mankhwala ozikidwa ndikulimbikitsa glycolysis, komwe kumapangitsa kuti shuga azikhala bwino ndi maselo komanso minyewa ya thupi. Kuphatikiza apo, pali kuchepa kwa mayamwidwe am'magazi ndimaselo a m'matumbo. Ubwino wawukulu wa metformin ndikuti siziyambitsa kuchepa kwambiri kwa glucose (m'munsimu muyezo) ndipo sizitsogolera pakupanga hypoglycemia.

Kuphatikiza apo, mapangidwe a Galvus adakumana ndi ophatikizira osiyanasiyana. Mapiritsi oterewa nthawi zambiri amathandizidwa kwa odwala omwe ali ndi matenda a shuga, chifukwa amathandizira kagayidwe ka lipid m'thupi, komanso amathandizira kuchepetsa kuchuluka kwa cholesterol yoyipa (kuwonjezera kuchuluka kwa zabwino), triglycerides ndi otsika kachulukidwe lipoproteins.

Mankhwalawa ali ndi mawonekedwe otsatirawa oti mugwiritse ntchito:

ngati chithandizo chakuchiritsa kwa matenda a shuga 2, pomwe chofunikira ndikusungabe zakudya zopatsa thanzi komanso kuchita masewera olimbitsa thupi moyenera.
kusintha zina za Galvus Met zogwira ntchito
Ngati chithandizo sichingathandize mutamwa mankhwalawa pogwiritsa ntchito mankhwala amodzi - metformin kapena vildagliptin,
mankhwalawa zovuta ndi insulin mankhwala kapena sulfonylurea.

Galvus adakumana ndi malangizo ogwiritsa ntchito akuwonetsa kuti mankhwalawa amachokera ku lumen ya m'matumbo ang'ono kulowa m'magazi. Chifukwa chake, mphamvu ya mapiritsi imawonedwa mkati mwa theka la ola atatha kutsata.

Chochita chogawidacho chimagawidwa mthupi lonselo, ndipo kenako chimataya limodzi ndi mkodzo komanso ndowe.

Hypoglycemic mankhwala Galvus Met - malangizo ntchito

Galvus Met ndi mankhwala ophatikiza a hypoglycemic omwe amachepetsa kuchuluka kwa shuga m'magazi.

Amagwiritsidwa ntchito pochiza matenda a shuga a mtundu wachiwiri kukhazikitsa bata ndipo nthawi zambiri thupi limavomereza.

Zambiri pazamankhwala

Chifukwa cha vildagliptin (chinthu chogwira ntchito), zotsatira zoyipa za peptidase enzyme zimachepetsedwa, ndipo kapangidwe ka glucagon ngati peptide-1 ndi HIP kumangowonjezera.

Kuchuluka kwa zinthuzi mthupi kumakhala kwakukulu kuposa kwabwinobwino, Vildagliptin imasintha ntchito ya maselo a beta mogwirizana ndi shuga, zomwe zimapangitsa kuti mahomoni azikhala ndi shuga.

Dziwani kuti kuwonjezeka kwa ntchito za beta-cell kumadalira kwathunthu kuwonongeka kwawo. Pachifukwa ichi, mwa anthu omwe ali ndi shuga othamanga, vildagliptin ilibe vuto pa kapangidwe ka insulin.

Chithandizo chogwira mankhwalawa chimawonjezera kuchuluka kwa glucagon-peptide-1 ndikukulitsa mphamvu ya maselo a alpha ku glucose. Zotsatira zake, kuphatikiza kwa glucagon kumawonjezeka. Kutsika kwa kuchuluka kwake mkati mwakudya kumapangitsa kuti chiwopsezo cha zotumphukira za cell chikhale ndi mahomoni omwe amatsitsa shuga.

Kuphatikizika, mawonekedwe omasulidwa

Mankhwalawa ali ngati mapiritsi, omwe amaphatikizidwa. Imodzi ili ndi zinthu ziwiri: Vildagliptin (50 mg) ndi Metformin, yomwe ili ndi milingo itatu - 500 mg, 850 mg ndi 1000 mg.

Kuphatikiza pa iwo, mapangidwe a mankhwala monga:

magnesium stearic acid,
hydroxypropyl cellulose,
hydroxypropyl methyl cellulose,
talcum ufa
titanium dioxide
chitsulo oxide chikasu kapena chofiira.

Mapiritsi amaikidwa m'matumba a zidutswa khumi. Phukusili lili ndi matuza atatu.

Pharmacology ndi pharmacokinetics

Kuchepetsa shuga kwa mankhwalawa kumadziwika chifukwa cha zomwe zimachitika pawiri:

Vildagliptin - imawonjezera ntchito ya masamba a pancreatic motsutsana ndi shuga wamagazi, omwe amatsogolera kaphatikizidwe ka insulin,
Metformin - imachepetsa kuchuluka kwa shuga m'thupi mwa kuchepetsa kuchuluka kwa chakudya, kumachepetsa kaphatikizidwe ka glucose ndi ma cell a chiwindi ndikuwongolera kugwiritsa ntchito zotumphukira.

Mankhwalawa amagwiritsidwa ntchito kuchititsa kuchepa kwamphamvu kwa shuga m'thupi. Komanso, nthawi zina, mapangidwe a hypoglycemia amadziwika.

Zinapezeka kuti kudya sikumakhudza kuthamanga ndi kuchuluka kwa mankhwalawa, koma kugwiritsidwa ntchito kwa zinthu zomwe zimagwira kumachepa pang'ono, ngakhale zonse zimatengera mlingo wa mankhwalawo.

Kuyamwa kwa mankhwala osokoneza bongo kumathamanga kwambiri. Mukamamwa mankhwalawa musanadye, kupezeka kwake m'magazi kumatha kupezeka mkati mwa ola limodzi ndi theka. Mu thupi, mankhwalawa amasinthidwa kukhala ma metabolites omwe amkatulidwa mkodzo ndi ndowe.

Zizindikiro ndi contraindication

Chizindikiro chachikulu chogwiritsidwa ntchito ndi mtundu wa 2 shuga.

Pali zochitika zingapo pamene muyenera kugwiritsa ntchito chida ichi:

mu mawonekedwe a monotherapy,
mukumwa mankhwala a Vildagliptin ndi Metformin, omwe amagwiritsidwa ntchito ngati mankhwala athunthu,
kugwiritsa ntchito mankhwalawa limodzi ndi othandizira omwe amachepetsa shuga ya magazi ndipo muli sulfanyl urea,
kugwiritsa ntchito mankhwala limodzi ndi insulin,
Kugwiritsa ntchito mankhwalawa ngati chofunikira pothandizira pa matenda a shuga a 2, pomwe zakudya zamthupi sizikuthandizaninso.

Zotsatira zakugwiritsa ntchito mankhwalawa zimawunikidwa ndi kuchepa kwakukhazikika kwa kuchuluka kwa shuga m'magazi.

Mowa kugwiritsa ntchito mankhwala sayenera:

tsankho kwa odwala kapena chidwi chachikulu ndi zigawo za chipangizo chachipatala,
mtundu 1 shuga
Pamaso pa opareshoni ndi njira ya x-ray, njira yodziwira matenda a radiotope,
ndimatenda a metabolic, ma ketoni akapezeka m'magazi,
chiwindi kuwonongeka ntchito ndi kulephera anayamba,
aakulu kapena owonda mtima kapena kupuma,
poyizoni woledzera,
zakudya zoperewera zopatsa mphamvu
mimba ndi mkaka wa m`mawere.

Musanayambe kumwa mapiritsi, muyenera kuonetsetsa kuti palibe zotsutsana.

Kufotokozera za mtundu wa kipimo

Patsamba lamankhwala, mankhwalawa amaperekedwa mwa mapiritsi okhala ndi mphamvu; aliyense wa iwo ali ndi zosakaniza ziwiri: 50 mg ya vildagliptin ndi 500, 850 kapena 1000 mg ya metformin. Magnesium stearate, hyprolose, hypromellose, talc, titanium dioxide, macrogol 4000 ndi iron oxide amagwiritsidwa ntchito ngati ojambula.

Chithuza chilichonse chimakhala ndi mapiritsi 10. Mbalezi zimayikidwa m'mabokosi azidutswa 3, phukusi lililonse Galvus Met ili ndi malangizo.

50/500 mg - mapiritsi ozungulira ndi m'mphepete mwa nkhanu yachikasu. LLO imafupikitsidwa mbali imodzi ndi NVR kumbuyo.
50/850 mg - mawonekedwe aphale ofanana, chipolopolo chokha ndi chachikasu ndipo chizindikirocho ndichoyenera: SEH mbali imodzi ndi NVR mbali inayo.
50/1000 mg - mapiritsi omwe amasiyana ndi mtundu wam'mbuyomu mumtambo wachikaso wambiri ndi kuphatikiza imvi ndi kufotokozera: NVR - kutsogolo ndi FLO - kumbuyo.

Kuthekera kwa hypoglycemic kwamankhwala kumadziwika ndi mitundu iwiri yazinthu zofunika kupanga, iliyonse yomwe ili ndi njira yake yochitira. Mphamvu zawo zovuta zimakupatsani mwayi wowongolera glycemia masana.

Vildagliptin - choletsa wa dipeptidyl peptidase-4 (DPP-4) - imakulitsa chidwi cha maselo kuti apange insulini, imawonjezera kupanga. Zotsatira zake zimaperekedwa ndi kukondoweza ndi mitundu ya gliptin yopanga mapuloteni ofunikira kwa kapamba - mtundu wa glucagon ngati peptide 1 (GLP-1) ndi glucose-insulinotropic polypeptide (HIP).
Metformin, gulu la gulu lalikulu la hydrochloride, imachepetsa kukomoka kwa glycemic pochepetsa kuchepa kwa mafuta m'matumbo aang'ono, kuchepetsa kupanga kwa glycogen mu chiwindi ndikuwonjezera kugwiritsidwa ntchito kwake mu zotumphukira. Phata limayambitsa hypoglycemia.

Pogwiritsa ntchito mankhwalawa pakamwa, vildagliptin ndi metformin amalowa m'magazi kudzera mu khoma lamatumbo, ndikufikira pazomwe zimachitika pakatha mphindi 25-30 ndikugawananso zigawo ndi ziwalo. Kupanga kwa metabolite Galvus Met kumachitika m'chiwindi. Pola impso zapamwamba ndi mkodzo. Nthawi yomwe theka la chizolowezi chogwiritsidwa ntchito chikuwonetsedwa pafupifupi maola atatu.

Panthawi yovuta yochizira ndi mankhwala awiri tsiku lililonse la metformin ya 1500-3000 mg ndi vildagliptin 50 mg, yogawa zokhudzana ndi 2 ntchito, kuchepa kwakukulu kwa shuga m'magazi kunalembedwa kwazaka zambiri. Nthawi yomweyo, mafakitala a glycosylated hemoglobin adatsika ndi 0,7%, poyerekeza ndi gulu lolamulira, lomwe limalandira metformin yokha.

Kwa odwala matenda ashuga omwe anali pa zovuta za Galvus Metom, kuwongolera kwakukulu kwa thupi sikunalembedwe. Popitilira milungu 24 yogwiritsa ntchito mankhwala osokoneza bongo, kuchepa kwakukulu kwa kuthamanga kwa magazi kwapezeka mwa odwala omwe ali ndi matenda a shuga a 2. Milandu ya Hypoglycemic inalemba ochepa.

Pamene Galvus Meta adalembedwa panthawi ya chithandizo ndi insulin (pa mlingo wa mayunitsi 41) mwa odzipereka odwala matenda ashuga omwe akuchita nawo kafukufukuyu, kuchuluka kwa hemoglobin ya glycosylated kudatsika ndi 0.72%. Hypoglycemia m'magulu oyesera komanso mu gulu la placebo sizinali zosiyana pakamodzi pafupipafupi.

Pogwiritsa ntchito kufanana kwa glimepiride (kuyambira 4 mg / tsiku) ndi Galvus Met, kuchepa kwakukulu kwa hemoglobin ya glycosylated kunalembedwanso - ndi 0,76%.

Vildagliptin

Ngati mumwa mapiritsi musanadye, zosakaniza mwachangu zimatenga msanga, mpaka zimatha pambuyo pa mphindi 105 mutayamba kumwa. Mukamagwiritsa ntchito mankhwalawa ndi chakudya, kuchuluka kwa mayamwidwe kumachepa pang'ono.

Mtheradi bioavailability wa mankhwalawa ndiwokwera kwambiri - 85%. Kugawa kwa metabolite pakati pa plasma ndi maselo ofiira a m'magazi ndi ofanana, kumangiriza pang'onopang'ono mapuloteni amwazi - 9,3% yokha.

Njira yayikulu yothetsera kuthetsa mankhwalawa ndi biotransfform, 69% ya mlingo mu thupi umasandulika kukhala wa cellacologically wosagwira metabolite ais151. Kutupa kwa vildagliptin kumachitika kudzera mu impso (85%) komanso matumbo (23%).

Oimira amitundu yosiyanasiyana, amuna kapena akazi, azinthu zosiyananso thupi amaonetsa pafupifupi pharmacokinetics omwewo a mankhwalawo.

Ndi hepatic osakwanira ofatsa kapena olimbitsa, bioavailability wa vildagliptin akutsikira ku 20%, mwa mawonekedwe owonjezereka amakula ndi 22%.

Ndi matenda a impso, mitundu yofatsa, yochepa komanso yolimba ya AUC, vildagliptin imakula 1.4 mpaka 2 nthawi.

Zotsatira za vildagliptin pa pharmacokinetics mwa ana sizinaphunzire.

Pa mlingo wa 500 mg, bioavailability ya metformin ndi 50-60% ngati atadyetsedwa musanadye. Ndi kuchuluka Mlingo, chizindikirocho chikuwonjezeka. Ngati mumwa mankhwalawo limodzi ndi chakudya, bioavailability amachepetsa.

Ndi gawo limodzi, metabolite sikugwirizana kwenikweni ndi mapuloteni a plasma (kuyerekezera, kukonzekera kwa sulfonylurea kumangiriza 90%). Pogwiritsa ntchito nthawi yayitali, mankhwalawa amalowerera m'magazi ofiira.

Jekeseni imodzi yokha ya mankhwalawa kwa odzipereka athanzi anasonyezanso kuperewera kwa impso komweko. Palibe ma metabolites omwe amapezeka m'chiwindi. Pa anthu odwala matenda ashuga, mpaka 90% ya mankhwalawa amachotsedwa ndi impso mkati mwa maola 24.

Kusiyana kwa kugonana sikumakhudza ma pharmacokinetics a mankhwalawa. Anthu odwala matenda ashuga amitundu yosiyanasiyana adalemba momwe ntchito za metformin zimathandizira.

Zomwe zimayamwa, kugawa ndikuchotsa mankhwalawa kwa odwala omwe ali ndi matenda a chiwindi sanaphunzire. Ndi aimpso a impso, theka la moyo limachulukitsidwa. Chifukwa cha kuchepa kwa impso, odwala okhwima amakhalanso ndi zotsatira zofananira. Palibe zambiri pazotsatira za mankhwalawa pazotsatira za ana.

Yemwe amawonetsedwa ngati mankhwalawo

Kuphatikiza kwake kumapangidwira kuti azichitira odwala matenda ashuga a mtundu 2.Kutengera ndi Galvus Meta, pali mitundu ina yazithandizo.

Monotherapy - kusintha shuga, amagwiritsa ntchito mankhwala amodzi - Galvus Met.
Kugwiritsira ntchito kokhapokha komwe kumagwiritsa ntchito Metformin ndi Vildagliptin ngati mankhwala odziyimira pawokha.
Kuphatikiza mankhwala motsatana ndi zotumphukira za sulfanylurea.
Njira yapatatu ndi kuphatikizira kwa insulin kwa Galvus Meta.
Monga mankhwala mzere woyamba womwe umagwiritsidwa ntchito kumayambiriro kwa mankhwala osokoneza bongo, pamene chakudya chochepa kwambiri cha carb ndi minofu yoyaka sichimatsogolera ku zotsatira zomwe mukufuna.

Galvus chithandizo chokomera amayi apakati komanso oyembekezera

Zoyesera pa nyama zapakati, zomwe zimagwiritsidwa ntchito Mlingo wa vildagliptin 200m kuposa momwe zimakhalira, zimawonetsa kuti mankhwalawa saphwanya chitukuko cha mazira ndipo alibe mphamvu. Kugwiritsa ntchito kwa Galvus Meta mu gawo la 1/10 kunawonetsa zotsatira zofananazo.

Mphamvu ya mankhwalawa pa mwana wosabadwa sanaphunzire bwino, kotero amayi apakati sanakhazikitsidwe. Metformin imadutsa mkaka wa m'mawere; palibenso chidziwitso pa malowedwe a vildagliptin.

Mwambiri, Galvus Met sigwiritsidwa ntchito poyamwitsa.

Kwa yemwe hypoglycemic wothandizirana wapatsidwa

Pathologies momwe metabolite sichinatchulidwe:

Katemera aliyense payekha, Hypersensitivity ku zilizonse za mankhwala,
Matenda a shuga 1 amtundu - omwe ali ndi matenda omwe amadalira insulin a mawonekedwe awa, insulin ndiyofunikira,
Masiku angapo opareshoni isanachitike, kuyesa kwa X-ray ndi radioisotropic, matenda owonetsa,
Mowa monga matenda kapena uchidakwa kamodzi,
Zakudya za Hypocaloric, zikafika 1000 kcal / tsiku kulowa thupi,
Nthawi iliyonse yapakati komanso pakubala,
Ana - chitetezo ndi mphamvu ya mankhwalawa sizinakhazikitsidwe.

Momwe mungagwiritsire ntchito mankhwalawa

Piritsi liyenera kumezedwa lonse, osafuna kutafuna kapena kusungunuka, kutsukidwa ndi madzi okwanira pamtunda wabwino. Ngati mumwa mapiritsi ndi chakudya, chiopsezo cha mavuto amachepetsa.

Mlingo wa Galvus Meta zimadalira kuchuluka kwa chipukutiro cha shuga, zotsatira za chithandizo cham'mbuyomu ndi analogues, komanso kutalika kwa matendawa. Mulimonsemo, dongosolo la chithandizo ndi dokotala.

Ngati mankhwalawa adayikidwa kwa nthawi yoyamba, monga kuwonjezera pakudya chamagulu osakwanira komanso zolimbitsa thupi, chizolowezi chake chikhale 50/500 mg (chizindikiro choyamba ndi vildagliptin, chachiwiri ndi metformin). M'tsogolomu, ndi osakwanira achire, omwe amatsimikiziridwa ndi njira zothandizira ntchito, mankhwalawa amatha kusintha.

Wodwala akakhala kuti amadziwa kale mankhwalawa (amawamwa mosiyana kapena kuphatikiza kwina), amalimbikitsa imodzi mwazosankha - 50/8 mg kapena 50/1000 mg.

Mu zaka zakukhwima kapena kukula kwa matenda a impso, muyezo wocheperako nthawi zambiri umalimbikitsa.

Kuti muwone zotsatira za chithandizo cha Galvus Metom, ndikofunikira kuyang'ana kuchuluka kwa shuga (onse kunyumba, ndi glucometer, ndi labotale) pafupipafupi.

Zotsatira zoyipa

Zotsatira zosafunika sizinalembedwe nthawi zambiri, koma ndikofunikira kuphunzira mndandanda musanayambe kugwiritsa ntchito odwala matenda ashuga.

Matumbo am'mimba - vuto la dyspeptic, kutentha kwa chifuwa, kapamba, kulawa kwazitsulo pakamwa, kusamwa bwino kwa vitamini B12.
CNS - kutayika kwa mgwirizano, mutu, manja akunjenjemera.
Chiwindi ndi bile ducts - chiwindi ndi chiwindi kukanika.
Musculoskeletal system - kuphatikizika ndi kupweteka kwa minofu.
Khungu - matuza, kutupa, khungu lowuma.
Metabolism - lactic acidosis (kuchuluka kwa kuchuluka kwa uric acid, acidic reaction ya chilengedwe).
Allergies - zotupa pakhungu, kuyabwa, urticaria, zimachitika kwambiri - Quincke's angioedema (kutupa kwa nkhope ndi ziwalo) ndi anaphylactic kugwedezeka (kugwa kwakukulu kwa kuthamanga kwa magazi, kothandizidwa ndi ziwalo zingapo).

Nthawi zina hypoglycemia imayamba ndi thukuta lakuthwa, manja akunjenjemera. Pazizindikiro zoyambirira, muyenera kumwa theka kapu ya tiyi wokoma kapena msuzi, idyani maswiti.

Malangizo apadera

Popereka mankhwala, wodwala matenda ashuga ayenera kuphunziranso yekha malangizowo. Malangizo apadera amathandiza kupewa mavuto.

Galvus Met simalo analogue a insulin, ndikofunikira, choyambirira, kwa odwala matenda ashuga omwe amadalira matenda a shuga.
Mankhwalawa ndi mankhwalawa, kuwunika pafupipafupi shuga a m'magazi (onse ogwira ntchito ndi a glucometer) ndi kovomerezeka. Zigawo za metabolite zimagwirizana ndi mankhwala ambiri, ndipo adotolo ayenera kudziwitsidwa zamankhwala onse akamalemba dongosolo la mankhwala.
Zotsatira za Galvus Meta pa zochitika zama psychomotor ndi kuchuluka kwa chidwi sizinaphunzire. Pogwira ntchito ndi makina ndi makina pakumwa mankhwalawa, munthu ayenera kusamala kwambiri.

Bongo

Ngati mlingo woyenera upitirira nthawi zambiri, myalgia, hypoglycemia, matenda osokoneza bongo, kutupa kwa malekezero, lactic acidosis (kuchokera ku kuchuluka kwa metformin) kumakula. Zizindikiro za bongo zimatha atasiya kulandira chithandizo.

Ndi zizindikiro zotere, mankhwalawa amachotsedwa, kutsukidwa ndimatumbo ndipo chithandizocho chimachitidwa. Kugwiritsa ntchito hemodialysis, ndi metformin yokha yomwe ikhoza kufufutidwa kwathunthu, vildagliptin ndiyotulutsa pang'ono.

Galvus Met - analogi

Ngati tikufanizira kapangidwe kake ndi zotsatira za chithandizo, ndiye kutengera ndi magwiridwe antchito komanso chithandizo chothandiza, analogues itha kukhala:

Malinga ndi malangizo, Galvus Met ndi yoyenera kugwiritsidwa ntchito mkati mwa miyezi 18 kuyambira tsiku lotulutsidwa, malinga ndi kusungidwa koyenera. Mankhwala omalizira ayenera kutayidwa. Malo amdima ndi owuma osayang'aniridwa ndi ana ndi oyenera kusungidwa, kutentha kwake mpaka 30 ° C.

Mankhwala omwe mumalandira amamasulidwa. Kwa mankhwala a Galvus Met, mlingo ndi womwe umatsimikizira mtengo wake:

50/500 mg - avareji ma ruble 1457,
50/8 mg mg - avareji ma ruble 1469,
50/1000 mg - pafupifupi 1465 rubles.

Ngakhale atagwiritsidwa ntchito kamodzi, sikuti anthu onse odwala matenda ashuga amakhutitsidwa ndi mtengowu, ambiri amadandaula kwa omwe amapuma pantchito ndi ndalama zochepa. Komabe, zopangidwa ndi kampani yaku Swiss Novartis Pharma nthawi zonse zimasiyanitsidwa ndi mtundu wawo wabwino, ndipo sakhala gawo la bajeti la othandizira anzawo.

Galvus Met - ndemanga za anthu odwala matenda ashuga komanso madokotala

Pamabwalo azodzisankhira, endocrinologists amayankha bwino pazotsatira za chithandizo cha Galvus Metom. Sitikulimbikitsidwa kuti mupeze zovuta zamavuto a oncological, popeza DPP-4, enzyme yomwe imalepheretsa kukula kwa neoplasms, imalepheretsedwa ndi Galvus Metom. Mu khansa ya kapamba, insulin nthawi zambiri imayikidwa. Ndemanga za odwala za Galvus Mete ndizosakanikirana, nkhani yayikulu pamikangano ndi mtengo wake.

Zambiri zokhudzana ndi mankhwala a Galvus Met ophatikizira hypoglycemic momwe insulin ndi glycogen imakhalira pa malangizo a boma, koma amaperekedwa pazidziwitso pokhapokha ndipo palibe chitsogozo chodziwitsa kapena kudzipatsa mankhwala.

Malangizo ogwiritsira ntchito

Mankhwala ayenera kumwedwa pakamwa ponse osatafuna.

Pofuna kusiyanitsa kukula kwa zoyipa, ndibwino kumwa mankhwalawo panthawi ya chakudya.

Dokotala amakhazikitsa muyeso wofunikira kwa wodwala aliyense, kuyambira pa lingaliro lake la kuchuluka kwa kuchuluka kwa shuga, zomwe wodwalayo adachitapo chithandizo kale komanso ngati zinali zothandiza.

Mlingo wofanana ndi piritsi limodzi kawiri patsiku, m'mawa ndi madzulo. Ngati mlingo umakhala kamodzi patsiku, ndiye kuti muyenera kumwa mankhwalawa m'mawa.

Zotsatira zoyipa ndi bongo

Kugwiritsa ntchito mapiritsi kungapangitse kukonzekera kwa zovuta za mankhwala, ndipo izi zimakhudza ziwalo ndi machitidwe awa:

Matumbo am'mimba - amayamba kusanza, kupweteka m'mimba, madzi am'mimba amaponyera m'munsi mwa esophagus, mwina kutupa kwa kapamba, kukoma kwazitsulo kumatha kuwonekera mkamwa, vitamini B akuyamba kuyamwa kwambiri.
Machitidwe amanjenje - kupweteka, chizungulire, manja akunjenjemera.
Chiwindi ndi ndulu - chiwindi.
Musculoskeletal system - kupweteka m'malo, nthawi zina.
Njira za metabolism - zimawonjezera kuchuluka kwa uric acid ndi acidity magazi.
Ziwengo - zotupa padziko khungu ndi kuyabwa, urticaria. Ndikothekanso kukulitsa zizindikiro zowopsa za thupi lawo siligwirizana, zomwe zimafotokozedwa ngati angioedema Quincke kapena anaphylactic.
Nthawi zina, zizindikiro za hypoglycemia zimawonekera, ndiko, kunjenjemera kwa malekezero apamwamba, "thukuta lozizira". Pankhaniyi, kukhathamiritsa kwa zakudya zamafuta (tiyi wokoma, confectionery) ndikulimbikitsidwa.

Ngati zotsatila za mankhwalawa zimayamba kukhazikika, ndiye kuti tifunika kusiya kugwiritsa ntchito mankhwalawa ndikupita kuchipatala.

Kuyanjana Ndi Mankhwala Ndi Analogi

Ngati mumagwiritsa ntchito Galvus Met ndi mankhwala ena, kukhazikika kwa zikhalidwe zamatenda kapena kuwonjezeka / kuchepa kwa mphamvu ya mankhwala omwe mumagwiritsa ntchito ndikotheka.

Pogwiritsa ntchito munthawi yomweyo ndi furosemide, kuchuluka kwa magazi a chiwiri kumawonjezereka, koma kuchuluka kwa koyambirira kumachepa.

Kutenga Nifedipine pa mankhwala kumabweretsa kuyamwa kwambiri, kuchulukitsidwa ndi impso, komanso kuwonjezeka kwa ndende ya Metformin m'magazi.

Ngati agwiritsidwa ntchito ndi glibenclamide, ndiye kuti kugwirizanitsa kwakumapeto kumayamba kuchepa.

Sitikulimbikitsidwa kuti titengedwe limodzi ndi Donazol, chifukwa imakhala ndi hyperglycemic. Ngati kuphatikiza kwa mankhwalawa ndikofunikira chifukwa chachipatala, ndiye kuti muyenera kusintha mulingo wa Metformin ndikuwonetsetsa kuchuluka kwa shuga m'magazi.

Mankhwala a diuretic, contracitive, glucocosteroid, calcium blockers, Phenothiazine - akagwiritsidwa ntchito limodzi ndi Galvus Met, amatha kuyambitsa hypoglycemia. Kugwiritsa ntchito osachepera 100 mg a Chlorpromazine palimodzi ndi Galvus Met patsiku, mutha kuwonjezera glycemia, komanso kuchepetsa kupanga insulin.

Pogwiritsa ntchito radiopaque wothandizira ndi ayodini nthawi yanthawi yamankhwala, lactic acidosis imayamba kupanga, yomwe imathandizidwa ndi kulephera kwa aimpso. Ngati mumwa mankhwala omwe amakhala ndi ethyl mowa nthawi yomweyo, ngozi ya lactic acidosis imakulanso.

Galvus Met ali ndi fanizo lotsatirali lazopanga zoweta: Avandamet, Glimecomb ndi Combogliz Prolong.

Avanta imakhala ndi zinthu ziwiri zogwira ntchito - Rosiglitazone ndi Metformin. Mankhwalawa amagwiritsidwa ntchito pochiza matenda enaake omwe amadzisokoneza. Rosiglitazone imawonjezera chidwi cha maselo kuti apange insulin, ndipo Metformin imachepetsa kaphatikizidwe ka shuga ndi chiwindi.

Glimecomb imapangidwa ndi Metformin ndi Glyclazide, yomwe imakupatsani mwayi wokhazikika wa shuga. Imavomerezeka kuti igwiritsidwe ntchito ndi mtundu wa matenda a shuga omwe amadalira inshuwaransi, chikomokere, kuyamwa, etc.

Comboglyz Prolong imakhala ndi Metformin ndi Saxagliptin. Amagwiritsidwa ntchito pothana ndi matenda a shuga a 2, pomwe sizingatheke kuchepetsa shuga ndi zakudya komanso zolimbitsa thupi. Iwo ali osavomerezeka kugwiritsa ntchito tsankho kwa zinthu zomwe zimakhalamo, matenda a shuga omwe amadalira insulin, ana, nthawi yapakati, nthawi ya msambo.

Maganizo a akatswiri ndi odwala

Malinga ndi ndemanga za madotolo ndi odwala za Galvus Met, titha kunena kuti mankhwalawa ndi othandizira kuchepetsa shuga. Zotsatira zoyipa ndizosowa kwambiri ndipo zimayimitsidwa ndi kuchepa kwa mlingo wa mankhwalawo.

Mankhwalawa ndi a gulu la mankhwala IDPP-4, adalembetsedwa ku Russia ngati njira yothetsera matenda a shuga 2. Ndiwothandiza komanso yotetezeka, yolekeredwa bwino ndi anthu odwala matenda ashuga, siyambitsa kulemera. Galvus Met imaloledwa kugwiritsidwa ntchito ndi kuchepa kwa impso, komwe sikungakhale kwapamwamba pochiza okalamba.

Mankhwala okhazikika. Zimawonetsa zotsatira zabwino pakuwongolera shuga.

Type 2 shuga mellitus adapezeka zaka khumi zapitazo. Ndinayesetsa kumwa mankhwala ambiri, koma sizinandithandizire kwambiri. Kenako adotolo adalangiza Galvus.

Ndidatenga kawiri patsiku ndipo posakhalitsa shuga adayamba kukhala wabwinobwino, koma zotsatira zoyipa za mankhwalawo zidawonekera, monga, kupweteka mutu komanso totupa. Dokotala adalimbikitsa kuti asinthane ndi kuchuluka kwa 50 mg, izi zidathandiza.

Pakadali pano, matendawo ndiabwino, pafupifupi kuyiwalako za matendawa.

Maria, wazaka 35, Noginsk

Zoposa zaka khumi ndi zisanu ndi matenda ashuga. Kwa nthawi yayitali, mankhwalawo sanabweretse zotsatira zabwino mpaka dokotala atalimbikitsa kugula Galvus Met. Chida chachikulu, mlingo umodzi patsiku ndi wokwanira kuteteza shuga. Ndipo ngakhale mtengo uli wokwera kwambiri, sindakana mankhwala, ndiwothandiza kwambiri.

Nikolay, wazaka 61, Vorkuta

-Mawu ochokera kwa Dr. Malysheva okhudza zinthu zomwe zitha kuthandiza ku matenda a shuga:

Mankhwalawa atha kugulidwa ku mankhwala aliwonse. Mtengo umachokera ku rubles 1180-1400., Kutengera dera.

Adalimbikitsa Zolemba Zina Zogwirizana

Kodi pali mitundu ya othandizira a hypoglycemic?

Mpaka pano, msika wogulitsa mankhwalawa umaphatikizapo mankhwala otere, Galvus ndi Galvus adakumana. Kusiyana kwakukulu kwa Galvusmet ndikuti imakhala ndi magawo awiri ogwira ntchito nthawi imodzi - metformin ndi vildagliptin.

Wopanga piritsi ndi kampani ya zamankhwala ku Germany ya Novartis Pharma Production GmbH. Kuphatikiza apo, m'masitolo ogulitsa mankhwala mutha kupeza zinthu zofanana ndi zopangidwa ndi Swiss.

Mankhwala amapezeka pokhapokha piritsi.

Kufotokozera kwa mankhwalawa m'malamulo ovomerezeka kumatanthauza kuti INN Galvus ndi vildagliptin, INN Galvus idakumana ndi vildagliptin metformin.

Musanatenge Galvus Met, ndikofunikira kuyang'ana pamankhwala omwe alipo:

Galvus adakumana ndi piritsi la 50 500 lolemba
Galvus adakumana ndi mapiritsi 50 m'mapiritsi ophatikizidwa,
Galapiritsi ya Galvus Met 50 1000 piritsi.

Chifukwa chake, manambala oyamba akuwonetsa kuchuluka kwa mamiligalamu a chinthu chomwe chili ndi vildagliptin, chachiwiri chikuwonetsa kuchuluka kwa metformin hydrochloride.

Kutengera ndi mapiritsi ndi kuchuluka kwake, mtengo wa mankhwalawa wakhazikitsidwa. Mtengo wamba wa Galvus meth 50 mg / 500 mg ndi pafupifupi ruble miliyoni ndi theka kwa mapiritsi atatu. Kuphatikiza apo, mutha kugula mankhwala ndi zidutswa 60 pa paketi iliyonse.

Contraindication pogwiritsa ntchito othandizira a hypoglycemic

Monga kukonzekera kulikonse kwachipatala, Galvus adakumana ndi zotsutsana zingapo komanso zoletsa kugwiritsa ntchito.

Funso la kugwiritsa ntchito mankhwalawa liyenera kutsimikiziridwa ndi adokotala okha.

Sizoletsedwa kugwiritsa ntchito wothandizira wa hypoglycemic nthawi yomwe mawonekedwe apadera a thupi kapena thupi akukhala.

Contraindication akuphatikiza ndi izi:

machitidwe a wodwala mu mawonekedwe a kusalolera kwa chimodzi kapena zingapo mankhwala.
ndi chitukuko cha matenda a shuga
asanachitike kapena atachitapo kanthu opaleshoni, kuyesa kwa matenda pogwiritsa ntchito njira zamakono,
ngati pali kuphwanya kwa kagayidwe kachakudya mthupi mu mawonekedwe a acetonemia,
pakusowa kwamadzi m'thupi, chifukwa pamakhala chiwopsezo cha matenda aimpso.
kulephera kapena kupweteka kwa impso,
matenda opatsirana pakukula kwambiri, mkhalidwe wa malungo.
kulephera kwa chiwindi
matenda osiyanasiyana a chiwindi, kuphatikizira hepatitis kapena cirrhosis,
kulephera kwamtima mu mawonekedwe owopsa kapena osakhazikika, ndi kupezeka kwa myocardial infarction,
ngati pali zovuta za kupuma zomwe zingayambitse kulephera kotere,
uchidakwa kapena mkhalidwe woledzera wa thupi,
kutsatira zakudya zosavomerezeka kapena kufa ndi njala (kuchuluka kwa ma kilocalories omwe amavomerezedwa tsiku lililonse ndi ochepera chikwi),
ana ochepera zaka khumi ndi zisanu ndi zitatu.

Munthawi ya bere, sikuletsedwa kugwiritsa ntchito mankhwala oterewa (hypoglycemic), chifukwa palibe chidziwitso chokwanira pakukula kwa mwana. Kuphatikiza apo, simuyenera kumwa mankhwala mukamayamwa.

Mpaka pano, maphunziro azachipatala sanachitidwe kuti adziwe zotsatira zake - kaya zinthu zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimachotsedwa pamodzi ndi mkaka wa m'mawere.

Zotsatira zoyipa komanso zovuta zoyipa

Kusagwiritsa ntchito mankhwalawa kwa hypoglycemic kumatha kuyambitsa zotsatira zoyipa zosiyanasiyana.

Kuthekera kwa mavuto kuyenera kuganiziridwanso pakuwerengera kuchuluka kwa mankhwalawa.

Zotsatira zoyipa zotere zimayamba kuoneka mbali ya ziwalo zosiyanasiyana zamkati ndi ziwalo zamthupi.

Choyamba, zotsatira za mankhwala zimatha kusokoneza:

Matumbo.
Machitidwe amanjenje.
Chiwindi.

Zotsatira zoyipa za thupi, chifukwa cha kumwa mankhwalawa, zimatha kuchitika monga:

Kuchepetsa mseru
kupweteka m'mimba
kupezeka kwa gastroesophageal Reflux, izi zimawonekera pakakhala kutulutsidwa kwa gastric acid kumunsi kwammphepete,
kufalikira ndi kuchuluka kwanyumba,
matenda ashuga
kutupa kwa kapamba mwa mawonekedwe a pancreatitis pachimake,
kuphwanya mayamwidwe abwinobwino a mavitamini a B,
kuwoneka kwa chitsulo chamkamwa,
kupweteka mutu kapena chizungulire,
chiwonetsero cha kunjenjemera miyendo yakumtunda,
zotupa mu chiwindi zomwe zimasokoneza ntchito yake,
kupweteka m'malo olumikizirana mafupa ndi minofu,
Kutupa kwa pakhungu, mawonekedwe a matuza
kuwonjezeka kwa kuchuluka kwa uric acid, komwe kumatha kuyambitsa lactic acidosis,
thupi lawo siligwirizana.

Ngati wodwala amwa mankhwalawa pamlingo wapamwamba, nseru, kusanza, kupweteka kwambiri m'misempha, kupweteka kwa thupi, kapena kutsika kwa shuga m'munsi mwa milingo yovomerezeka kumatha kuchitika.

Ngati ndi kotheka, dokotala yemwe akupezekapo angakulimbikitseni kusintha mankhwalawa ndi analog mankhwala (otsika mtengo kapena okwera mtengo).

Kumwa mankhwala otere, zinthu zotsatirazi ziyenera kuganiziridwa:

Mapiritsi amaletsedwa kugwiritsa ntchito akamwa zakumwa zoledzeretsa.
Osachepera kamodzi pamasabata angapo, kafukufuku wofufuza matenda amayenera kuchitidwa kuti adziwe momwe chiwindi ndi impso zimayendera.
Zotsatira zosiyanasiyana za mankhwalawa zomwe zimagwiritsidwa ntchito ndi magulu ena ndi makalasi zitha kudziwika. Chifukwa chake, dokotala wopezekapo amayenera kudziwa kumwa mankhwala aliwonse pofuna kupewa kuwonetsa zotsatira zoyipa chifukwa chogwiritsa ntchito zovuta.
Sitikulimbikitsidwa kuti tichite ntchito zosiyanasiyana zomwe zimafuna kuti anthu azikumbukira.

Kuphatikiza apo, kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumatha kuyambitsa matenda a metabolic. Zotsatira zake, kuchepa kwa magazi m'thupi kapena minyewa imayamba.

Kodi umboni wa ogula ndi akatswiri azachipatala ndi uti?

About mankhwala Galvus adakumana ndi ndemanga zosiyanasiyana. Monga lamulo, kuchokera kumbali zosavomerezeka za mankhwalawo, ogula amapereka mtengo wokwera kwambiri kwa mankhwalawo. Mwambiri, kwenikweni, kuyika mapiritsi ndi mulingo wocheperako wa metformin kumasiyana m'chigawo cha rubles chikwi chimodzi ndi theka.

Tiyenera kudziwa kuti odwala ambiri alibe madandaulo chifukwa cha mtundu wawo komanso ntchito yake yabwino. M'malingaliro awo, mankhwalawa amayamba kuchitapo kanthu mwachangu ndikubweretsa zotsatira zabwino. Kuphatikiza apo, mwa zina zabwino za mapiritsi oterewa ndikuti odwala matenda ashuga amatha kugula magulu ena azinthu kuchokera pamndandanda woletsedwa.

Malinga ndi madotolo, mtengo wokwera wa mankhwalawo umadzilungamitsa. Kuphatikiza apo, Metformin yokha (monga piritsi yokonzekera piritsi) siyotsika mtengo, ndipo ndalama zochulukirapo zimafunikira kuti apangidwe ndi kapangidwe ka vildaglipin.

Akatswiri azachipatala, potengera mphamvu ya mankhwalawa, adziwe kuti mulingo wokwanira mtengo uli mkati mwazinthu zonse. Kumwa mankhwalawo kumayenderana ndi kukhazikika kwa shuga wamagazi, kusintha kwa thupi kwambiri komanso kusintha kwamtundu wa wodwala.

Mankhwala a Hypoglycemic akufotokozedwa mu kanema m'nkhaniyi.

Sonyezani shuga yanu kapena sankhani jenda kuti muyimikize.

Galvus Met: malangizo ogwiritsira ntchito. Momwe mungatengere m'malo mwake

Mapiritsi a Galvus ndi Galvus Met A shuga: Phunzirani Zonse Zomwe Mukufuna. Otsatirawa ndi buku lophunzitsira lolemba m'chinenero chomveka. Phunzirani zowonetsera, contraindication ndi Mlingo.

Galvus Met ndi mankhwala othandiza odwala matenda ashuga amtundu wa 2, omwe ali odziwika kwambiri, ngakhale ali ndi mtengo wokwera. Imachepetsa shuga m'magazi ndipo sikuti imayambitsa mavuto akulu.

Zosakaniza zomwe zimagwiritsidwa ntchito pophatikiza ndi vildagliptin ndi metformin. Mapiritsi a Galvus ali ndi vildagliptin yoyera, yopanda metformin.

Werengani mayankho a mafunso:

Yanumet kapena Galvus Met: omwe mankhwalawa ali bwino.
Momwe mungamwe mapiritsi awa kuti pasakhale m'mimba.
Kugwirizana kwa Galvus ndi Galvus Met ndi mowa.
Momwe mungasinthe vildagliptin ngati sichithandiza kapena ndiokwera mtengo kwambiri.

Galvus ndi Galvus Met: nkhani yatsatanetsatane

Galvus ndi mankhwala atsopano. Zinayamba kugulitsa zaka zosakwana 10 zapitazo. Mulibe malo otsika mtengo otetezera nyumba, chifukwa patent sichitha.

Pali zithunzi za opanga opikisana - Yanuviya ndi Yanumet, Onglisa, Vipidiya ndi ena. Koma mankhwalawa onse amatetezedwa ndi ma Patenti ndipo ndiokwera mtengo.

Pansi pake amafotokozedwa mwatsatanetsatane kuti ndi mapiritsi otchipa omwe mungathe kusintha m'malo mwa vildagliptin ngati simungathe kugula mankhwalawa.

Galvus kapena Galvus Met: ndibwino bwanji? Zimasiyana bwanji?

Galvus ndi vildagliptin koyera, ndipo Galvus Met ndi mankhwala ophatikiza okhala ndi vildagliptin ndi metformin. Mwambiri, metformin imatsitsa shuga m'magazi odwala matenda ashuga kuposa vildagliptin.

Chifukwa chake, muyenera kutenga Galvus Met, pokhapokha ngati wodwala ali ndi contraindication yayikulu pakusankhidwa kwa metformin. M'masiku oyambirira a chithandizo, kutsegula m'mimba, kunyansidwa, kutulutsa magazi ndi matenda ena am'mimba kumatha kuchitika. Koma ndikofunikira kudikirira ndikudikirira mpaka adutse.

Zotsatira zamankhwala zomwe zimakwaniritsidwa zimakusangalatsani chifukwa chazovuta.

Yanumet kapena Galvus Met: ndi mankhwala ati omwe amaposa?

Yanumet ndi Galvus Met ndi mankhwala ofanana kuchokera kwa opanga awiri osiyanasiyana omwe amapikisana. Ali ndi mtengo wofanana. Kulongedza mankhwala Yanumet ndi okwera mtengo, koma amakhala ndi miyala yambiri. Palibe mwa awa mankhwalawa omwe ali ndi ma analogues otsika mtengo, chifukwa mankhwalawa onse akadali atsopano, otetezedwa ndi ma Patent.

Mankhwalawa onse adatenga ziwonetsero zabwino kuchokera kwa odwala olankhula Chirasha omwe ali ndi matenda a shuga a 2. Tsoka ilo, kulibe chidziwitso pakadali koyankha molondola kuti ndi iti mwa mankhwalawa amachepetsa shuga yamagazi. Onse ali abwino komanso otetezeka.

Kumbukirani kuti popanga mankhwalawa, Yanumet metformin ndi yofunika kwambiri kuposa sitagliptin.

Galvus kapena metformin: ndibwino bwanji?

Wopangayo akuti vildagliptin ndiye chinthu chachikulu chogwiritsa ntchito pamapiritsi a Galvus Met. Ndipo metformin ndi gawo lothandiza chabe.

Komabe, Dr. Bernstein akuti metformin amatsitsa shuga koposa magazi a vildagliptin. Galvus Met ali ndi ndemanga zabwino kwambiri za odwala pakati pa mitundu yonse yatsopano ya 2 shuga.

Pali lingaliro kuti gawo lalikulu pakupambana ili limaseweredwa ndi metformin wakale wakale, osati vildagliptin yatsopano yokhala ndi mawu.

Galvus Met yodula imathandizira pang'ono kuchokera ku shuga wambiri kuposa miyala yotsika mtengo ya pureform.

Komabe, zimasintha pang'ono zotsatira za chithandizo cha matenda ashuga, ndipo zimawononga kangapo kuposa Siofor kapena Glucofage. Ngati mwayi wazachuma ungalole, tengani vildagliptin + metformin.

Ngati mukusowa ndalama, mutha kusinthira ku metformin yoyera. Chithandizo chake chabwino kwambiri ndi mankhwala oyambitsidwa kunja, Glucofage.

Mapiritsi a Siofor nawonso ndi otchuka. Mwina amachita moperewera pang'ono kuposa Glucofage, komanso zabwino. Mankhwalawa onse amakhala otsika mtengo kuposa Galvus Met. Mutha kupeza ndi miyala yotsika mtengo ya metformin yopangidwa ku Russia ndi mayiko a CIS, koma ndibwino osazigwiritsa ntchito.