Novorapid ndi mankhwala osinthika mwanjira inayake, omwe safuna kudya zakudya zowonjezera, ndipo jakisoni amatha kuchitidwa mukatha kudya komanso musanadye. Achire zotsatira kumatenga pafupifupi 4 maola. Insuman Rapid ndi analogue ya munthu mahomoni, kudya komwe kumalumikizidwa ndi chakudya kapena kusuta nthawi zonse, komanso kuyambitsa jekeseni wa subcutaneous mphindi 40 asanadye. Kutalika kwa zotsatira zake ndi pafupifupi maola 6. Zithandizo zonse ziwiri ndizifupi, ndipo madokotala nthawi zambiri amasintha zina ndi zina popanda kuvulaza thanzi la wodwalayo.

Chidule cha Mankhwala Osokoneza bongo

Novorapid ndi m'gulu la mankhwala aposachedwa kwambiri. Mankhwalawa amathandizira kupanga kuperewera kwa mahomoni amunthu, ali ndi mawonekedwe komanso zabwino zingapo pazamankhwala ena amtundu womwewo:

• Mwachangu digestibility.
• Kuponya shuga msanga.
• Kuperewera kwa kudalira zakudya zazosalekeza.
• Chiwonetsero cha Ultrashort.
• Mafomu otulutsidwa.

Novorapid motsutsana ndi endocrine matenda amapezeka m'malo obweretsera magalasi (Penfill) ndi ma pensulo okonzeka (FlexPen). Gawo la mankhwala omwe ali mumitundu yonseyi kumasulidwa ndi zofanana. Mankhwalawa amaikidwa bwino, ndipo mahomoni enieniwo ndi osavuta kugwiritsa ntchito mu mtundu uliwonse wa mankhwala.

Zophatikizira ndi kapangidwe

Kupanga kwakukulu kwa Novorapid kumawerengeredwa potengera zonse zomwe zimapangidwa ndi 1 ml ya mankhwalawa. The yogwira ndi insulin aspar 100 magawo (pafupifupi 3.5 mg). Pazinthu zothandizira, pali:

• Glycerol (mpaka 16 mg).
• Metacresol (pafupifupi 1.72 mg).
• Zink chloride (mpaka 19.7 mcg).
• Sodium chloride (mpaka 0,57 mg).
• Sodium hydroxide (mpaka 2.2 mg).
• Hydrochloric acid (mpaka 1,7 mg).
• Phenol (mpaka 1.5 mg).
• Madzi oyeretsedwa (1 ml).

Chida chake ndi yankho lomveka popanda mtundu wotchulidwa, phokoso.

Magazi

Novorapid ali ndi tanthauzo la hypoglycemic chifukwa chachikulu cha insulin. Mtundu wa insulin uwu ndi chithunzi cha mahomoni amfupi aanthu. Thupi limapezeka chifukwa cha njira zosiyanasiyana zaumisiri pamlingo wa DNA yomwe ikubwezeretsanso. Insulin Novorapid amalowa muubwenzi wachilengedwe ndi ma cell receptors, ndikupanga zovuta zingapo zamathero amitsempha.

Mankhwalawa amatha kugwiritsidwa ntchito ngati mtundu uliwonse wa matenda ashuga mwa akulu ndi ana kuyambira zaka 2!

Poyerekeza ndi kuchepa kwa mndandanda wa glycemic, kuwonjezereka kwazowonjezera kwamitsempha yama cell, kuyambitsa kwa mapikidwe a lipogenesis ndi glycogenogeneis, komanso kuwonjezeka kwa mayamwidwe osiyanasiyana a minofu yofewa. Nthawi yomweyo, kupanga shuga ndi ziwindi kumachepetsa. Novorapid imalumikizidwa bwino ndi thupi, imakhala ndi machiritso othamanga kwambiri kuposa insulin yachilengedwe. Maola atatu oyambirira atatha kudya, insulin aspart imachepetsa shuga ya plasma mwachangu kwambiri kuposa insulin yomweyo yaumunthu, koma zotsatira za Novorapid ndizofupikitsa ndi jakisoni wa subcutaneous kuposa kuchokera ku insulin yachilengedwe yopangidwa ndi thupi la munthu.

Zizindikiro ndi contraindication

Mankhwalawa ali ndi chidziwitso chachikulu - matenda a shuga amtundu uliwonse mwa ana kuyambira zaka 2, achinyamata ndi odwala akuluakulu.

Kugwiritsa ntchito othandizira a hypoglycemic ayenera kuthandizidwa mosamala chifukwa cha zovuta zina. Novorapid ali osavomerezeka kuti agwiritsidwe ntchito ndi tsankho la munthu pazigawo zina, zimayambitsa matupi amtundu uliwonse wa Novorapid.Zowonjezera zothandizira ana osaposa zaka 2 sizikudziwika chifukwa cha kuchepa kwa maphunziro azachipatala kwa odwala a m'badwo uno.

Malangizo apadera

Chimodzi mwazovuta zomwe zimachitika ndi makonzedwe atsatanetsatane ndi hypoglycemia. Nthawi zambiri, kusokonezekaku kumachitika chifukwa cha kuchuluka kwa mankhwalawa, ndikuphwanya kwa regimen. Novorapid ali ndi nthawi yofupikirako, koma amayambira mwachangu. Izi zimachepetsa chiopsezo cha nocturnal hypoglycemia. Mlingo umasankhidwa mosiyanasiyana payekha, zomwe zimachitika chifukwa cha mbiri yakale yachipatala, zomwe zimayambitsa matenda ochulukirapo, matenda ndi chikhalidwe cha matenda ashuga. Ndi mbiri yodwala matenda, tikulimbikitsidwa kuyang'anira kwambiri index ya glycemic m'magulu onse a odwala. Novorapid angayambitse kuyipa kwa ana aang'ono.

Analogi ndi ma genetic

Hororapid ya mahomoni ingathe kusinthidwa ndi mankhwala ena a gulu lomweli. Analogs amasankhidwa pokhapokha atamuwunika mozama kuchipatala. Zofananira zazikulu zimaphatikizapo Humalog, Actrapid, Protafan, Gensulin N, Apidra, Novomiks ndi ena. Mtengo wa mahomoni a Novorapid m'malo osiyanasiyana umasiyana 1800 mpaka 2200 phukusi lililonse.

Novomix itha kukhala m'malo mwa Novorapid.

Kufotokozera kwa mahormone

• Hormone insulin 3,571 mg (100 IU 100% ya anthu sungunuka).
• Metacresol (mpaka 2.7 mg).
• Glycerol (pafupifupi 84% = 18.824 mg).
• Madzi a jakisoni.
• Sodium dihydrogen phosphate dihydrate (pafupifupi 2.1 mg).

Insuman insuman mwachangu gt choyimiriridwa ndi madzi opanda khungu owonekera bwino kwambiri. Ndi m'gulu la othandizirana mwachidule. Insuman siimapanga ngakhale malo osungika nthawi yayitali.

Mankhwala a Pharmacodynamic

Insuman Rapid GT ili ndi mahomoni ofanana mwanjira yofanana ndi mahomoni amunthu. Mankhwalawa amapezeka ndi mainjiniya. Njira zazikuluzikulu za zochita za Insuman ndi monga:

• Kutsika kwa m'magazi a m'magazi.
• Kuchepetsa njira za catabolic.
• Kulimbikitsa kusunthira kwa shuga mkati mwamaselo.
• Kuwongolera akuti lepogisis m'magazi a chiwindi.
• Kulimbikitsa kulowa kwa potaziyamu.
• Kukhazikitsa kwa mapuloteni ndi amino acid.

Insuman Rapid GT Imayamba mwachangu, koma ili ndi nthawi yochepa. Hypoglycemic kwenikweni zimatheka kale theka la ola pambuyo subcutaneous makonzedwe a mankhwala. Zotsatira zimatha mpaka maola 9.

Zotsatira zotsatirazi ziyenera kudziwitsidwa ndikuwonetsa zazikulu:

• Matenda a shuga (mtundu wodalira insulin).
• Coma pa maziko a matenda ashuga.
• Kupita patsogolo ketoacidosis.
• Kufunika kokulipitsidwa kwa metabolic (mwachitsanzo, musanachitike kapena pambuyo pa opaleshoni).

Milandu yayikulu ikuphatikiza hypoglycemia kapena chiwopsezo chachikulu cha kuchepa kwambiri kwa shuga m'magazi, matupi awo sagwirizana ndi magawo aliwonse omwe amapangidwa ndi mankhwala, kumva kwambiri.

Popereka mankhwala Insuman Rapid GT adokotala amatenga zifukwa zingapo: zaka, mbiri yakale yachipatala, njira zambiri za matenda ashuga, kupezeka kwa matenda opweteka a ziwalo zamkati ndi ziwonetsero zina za pathologies. Nthawi zina kumwa mankhwala a shuga kumalepheretsa kuyendetsa galimoto kapena kugwira ntchito m'mafakitori owopsa.

Mtengo wapakati wa mankhwalawa m'magawo osiyanasiyana umasiyana 700 mpaka 1300 rubles pa phukusi lililonse.

Mtengo Zimatengera zinthu zambiri zosiyanasiyana.

Mankhwalawa onse ndi omugwiritsa ntchito mwachidule. Kusintha kulikonse kwa mankhwala motsutsana ndi matenda a shuga kumachitika pokhapokha mukaonana ndi katswiri. Insuman Rapid GT imakupatsani mwayi wokhala ndi moyo wabwino wodwalayo pazinthu zosiyanasiyana za matenda ashuga. Novorapid ali ndi katundu wofanana ndi Insuman Rapid GT, koma pafupifupi chimabwereza kwathunthu insulin ya anthu.

Insulin "Insuman Rapid GT" ithandizanso kupereka msanga-kuchepetsa msanga zinthu zomwe zimachitika mphindi iliyonse.Kupatula apo, matenda ashuga ndi matenda oopsa omwe nthawi zambiri amachititsa kufa kapena kulumala. Kuti mupeze yankho la panthawi yake, othandizira osasinthika ndi jakisoni wa insulin yofulumira.

Kapangidwe ndi mfundo zowonetsera thupi

Mu 1 ml ya mankhwala muli:

• 100 IU ya insulin yosungunuka yofanana ndi anthu, omwe amafanana ndi 3,571 mg ya mahomoni amunthu.
• Zowonjezera:
  • glycerol 85%,
  • metacresol
  • sodium hydroxide
  • hydrochloric acid
  • sodium dihydrogen phosphate dihydrate,
  • madzi osungunuka.

Mankhwala a hypoglycemic "Insuman Rapid GT" amatanthauza insulin yochepa. Dzinalo Losayenerana Padziko Lonse (INN) -. Akatswiri opanga magesi a Gene adatha kusungunuka kwathunthu, ofanana ndi anthu, insulini. Imakhala ndi njira yochizira, yokhala ndi maola 9. Mphamvu yochepetsera shuga imadziwonekera pakatha mphindi 30, ikufika pachimake, pafupifupi, pambuyo pa maola awiri ndi atatu, kutengera kagayidwe ndi ntchito ya impso.

Mankhwala amakhudza thupi motere:

Mankhwala amathandizira kupanga glycogen.

• amathandiza kuchepetsa shuga
• imayambitsa kaphatikizidwe kazakudya,
• Imathandizira kukhutitsa maselo amwazi ndi potaziyamu
• amaletsa kusweka kwa lipid,
• imathandizira njira yosinthira shuga kuchokera ku chakudya chamafuta kukhala mafuta acids,
• amakwaniritsa maselo okhala ndi ma amino acid,
• kumawonjezera mapangidwe a glycogen,
• bwino kugwiritsa ntchito mankhwala omaliza a shuga kagayidwe,
• amachepetsa kuchuluka kwa njira za catabolic.

Syringe cholembera "Solostar" yogwiritsidwa ntchito kamodzi ingapangitse kuti magwiritsidwe ntchito a insulin akhale ochepa. Sichitenga nthawi yayitali komanso mosamala kukoka mankhwalawo mu syringe ya insulin: jakisoni yayamba kale jakisoni.

Zizindikiro ndi malangizo ogwiritsa ntchito

Insulin yovomerezeka imasonyezedwa kuti igwiritsidwa ntchito:

• odwala omwe amadalira insulin omwe ali ndi matenda a shuga,
• pochotsa matenda a hyperglycemic coma ndi kuchiza ketoacidosis,
• ngati cholowa pakuthandizira opaleshoni ya matenda ashuga.

Kuti muchepetse kuopsa kwa muyezo wolakwika wa mankhwalawa musanagwiritse ntchito, sikokwanira kungowerenga malangizo oti mugwiritse ntchito. Ndikofunikira kufunsa dokotala ndikuwerengera payekha payekha, zomwe zimatengera zinthu zambiri. Zambiri mwa izo ndi:

• kuchuluka kwa zochita zolimbitsa thupi za wodwala,
• kakhalidwe
• chakudya
• jenda, zaka komanso kulemera
• kumwa mankhwala ena
• kukhalapo kwa matenda osachiritsika.

Tiyenera kudziwa kuti ngati chimodzi mwazina zomwe zalembedwazo zasinthidwa, muyenera kufunsa dokotala kuti mupezenso kuchuluka kwa mankhwalawa. Ngakhale kusintha pang'ono kwa thupi kumatha kubweretsa zotsatirapo zosasangalatsa ngati simusintha mlingo wa insulin nthawi.

Malangizowa ali ndi malangizo onse kwa odwala onse:

• Mankhwalawa amaperekedwa pansi pa khungu musanadye kwa mphindi 15-20.
• Popewa kutulutsa khungu, ndikofunikira kupaka jakisoni m'malo osiyanasiyana nthawi zonse.
• Mtengo wa metabolism ndi pafupifupi 50% ya tsiku lililonse la insulin.
• Patsiku, thupi limafunikira insulini ndi 0,5-1.0 IU pa 1 kg yakulemera kwa thupi.
• Mankhwalawa amatha kuthandizidwa kudzera mu kuyang'aniridwa ndi madokotala kuchipatala.

Contraindication ndi zoopsa zomwe zingachitike

Nthawi ya mkaka wa m'mawere ndi kuyambika kwa pakati pathupi si kuphwanya magazi, choncho simuyenera kusokoneza kudya kwa insulin. Komabe, chifukwa cha kusintha kwa kulemera kwa thupi, dokotala yemwe akupezekapo ayenera kusintha mankhwalawo. Kuopsa kwa kugwiritsa ntchito insulin mwachangu kumalumikizidwa ndi kuwerengera kosayenera kwa mankhwalawa, komwe kumayambitsa hypoglycemia. Zizindikiro izi za hypoglycemia zimachitika.

Insuman Rapid GT - malangizo a boma ogwiritsira ntchito

Insuman Rapid GT 100 I.U./ml

Nambala yolembetsa : P No. 011995/01 ya Julayi 26, 2004.

1 ml ya njira yopanda mbali ya jakisoni ili ndi 100 IU ya insulin ya anthu. Omwe amathandizira: m-cresol, sodium dihydrogen phosphate dihydrate, glycerol, sodium hydroxide, hydrochloric acid, madzi a jakisoni.

Contraindication Insuman Rapid GT

• achina,
• Hypersensitivity zimachitikira insulin kapena chilichonse chothandiza cha mankhwala.

Ndi chisamaliro mankhwalawa ayenera kugwiritsidwa ntchito ngati aimpso alephera (pakhoza kukhala kuchepa kwa insulin chifukwa cha kuchepa kwa insulin metabolism), odwala okalamba (kuchepa pang'onopang'ono kwa ntchito ya impso kungayambitse kuchepa kwathunthu kwa kufunika kwa insulin), mwa odwala omwe ali ndi vuto la insulin (kufunika kwa insulin kumatha kuchepa chifukwa kuchepa kwa kuthekera kwa gluconeogeneis ndi kuchepa kwa insulin kagayidwe kake, odwala omwe ali ndi vuto lalikulu la matenda amitsempha yamagazi ndi ziwongo (hypoglycemic episode makamaka ndi zamankhwala, popeza pali chiopsezo cha mtima kapena matenda a mtima (hypoglycemia), mwa odwala omwe ali ndi proliferative retinopathy (makamaka omwe sanalandire chithandizo ndi photocoagulation (laser therapy), chifukwa ali ndi chiopsezo chocheperapo kapenaurosis yokhala ndi hypoglycemia - khungu lonse ), mwa odwala omwe ali ndi matenda ogwirizana (kufunika kwa insulin nthawi zambiri kumawonjezeka).

Mlingo umasankhidwa payekha, moyang'aniridwa ndi dokotala. Lowani nthawi zambiri maola 4 kapena 6 aliwonse

Hypoglycemic mankhwala, osakhalitsa insulin. Insuman Rapid ili ndi insulin, yofanana ndi insulin yaumunthu ndipo yopezeka ndi mainjiniya ogwiritsa ntchito K12 kufinya E. coli.

Insulin imachepetsa kuchuluka kwa shuga m'magazi, imalimbikitsa zotsatira za anabolic komanso imachepetsa zotsatira za catabolic. Imawonjezera mayendedwe a glucose mkati mwa maselo ndi mapangidwe a glycogen mu minofu ndi chiwindi, imathandizira kugwiritsa ntchito pyruvate, ndipo imalepheretsa glycogenolysis ndi glyconeogeneis. Insulin imakulitsa lipogenesis mu chiwindi ndi minofu ya adipose ndikuletsa lipolysis. Zimathandizira kutuluka kwa ma amino acid m'maselo ndi kaphatikizidwe wa mapuloteni, kumapangitsa kuti potaziyamu ayambe kuyenda.

Insuman Rapid ndi insulini yomwe imayamba mwachangu komanso yochepa nthawi yochitapo kanthu. Pambuyo pa utsogoleri wa sc, mphamvu ya hypoglycemic imachitika pakangotha ​​mphindi 30, ikafika pazowonjezereka mu maola 1-4, imapitilira maola 7- 7.

Kutulutsa mafomu, mtengo wake

Insulin basal imapezeka ngati subcutaneous kuyimitsidwa mu Mlingo wa 100 IU / ml. Mtundu woyamba wamasulidwa ndi mabotolo a galasi owoneka bwino. Mbali yapamwamba ya botolo imatsekedwa ndi choletsa, pomwe amavala chipewa cha aluminium. Kuti ziwonjezeke, chipewa cha pulasitiki chimayikidwa pamwamba pa chipewa. Kuchuluka kwa botolo ndi 5 ml. Patsamba la mankhwala, insulin Bazal imatha kuwoneka m'matumba a ma ampoules asanu omwe ali ndi malangizo ogwiritsa ntchito.

Mtundu wotsatira wa kumasulidwa ndi makatoni omwe amapangidwa ndi galasi lomveka bwino lomwe lili ndi 3 ml. Pamwamba pa katiriji wokutidwa ndi chowiyimitsa, ndipo chophimba cha aluminium chimavalidwa pamwamba pake. Gawo lakumapeto limatsirizika ndi plunger. Kuphatikiza apo, pali mipira itatu yachitsulo katiriji. Phukusi lililonse limakhala ndi ma cartridge 5. Amafunanso cholembera.

Fomu lachitatu lomasulidwa ndi makatoni ku SoloStar disposable syringe pens. Amapangidwa ndi galasi lomveka bwino lomwe lili ndi 3 ml. Kunja, cartridge imawoneka chimodzimodzi monga momwe idalili kale. Pamwamba pa cork pali kapu ya aluminium pamwamba. Gawo lakumunsi la cartridge limatha ndi plunger. Kathumba kalikonse kamakhala ndi mipira 3 yachitsulo. Poterepa, phukusi limakhala ndi zolembera 5 ndi malangizo ogwiritsira ntchito.

Mtengo wapakati wa mankhwalawa umasiyanasiyana pafupifupi ma ruble 1000. Mtengo umatengera mtundu womwe wasankhidwa kuti amasulidwe.

Kuchiritsa katundu

Mphamvu ya hypoglycemic ya Insuman Bazal imatheka chifukwa cha gawo lake - insulin-isophan. Thupi lomwe limapangidwa ndi momwe limapangidwira limafanana ndi mahomoni omwe amapangidwa m'thupi la munthu. Imapezeka kudzera mujini.

Mankhwala ndi a gulu la mankhwala a sing'anga nthawi ya kuchitapo. Pambuyo makonzedwe, subcutaneous chimamangiriza kwa ena zolandila za nembanemba wa cell, ndikupanga zovuta zina zomwe zimayambitsa njira zothandizira. Imachepetsa shuga mwakuchulukitsa kayendedwe kake, imathandizira mayamwidwe, kuletsa kaphatikizidwe ka chiwindi, ndikuwongolera njira za metabolic ndi kutenga nawo mbali.

Kutalika kwa mphamvu ya mankhwalawa kumatengera kuthamanga komwe insulin imalowa mu thupi, mlingo, malo a jekeseni, komanso njira yoyendetsera. Chifukwa chake, insulin imagwira ntchito makamaka osati mu odwala matenda ashuga osiyanasiyana, koma ngakhale mwa wodwala m'modzi.

Malingaliro apamwamba a isofan: nthawi yoyambira - ola limodzi ndi theka atatha kubayidwa, mphamvu yayikulu imawonekera pakapita maola 4-12, nthawi ya hypoglycemic - mpaka tsiku 1.

Mankhwalawa amagawidwa paminyewa ingapo, osatha kudutsa mkaka ndi placenta. Amagwiritsidwa ntchito mochuluka m'chiwindi ndi impso. Amathira mkodzo.

Njira yogwiritsira ntchito

Zochitika zonse zamagwiritsidwe a Insuman Bazal GT (Mlingo, nthawi ya makonzedwe, cholinga cha shuga) ziyenera kutsimikizika ndi kusinthidwa mosiyanasiyana payekhapayekha, poganizira kadyedwe ka wodwalayo komanso zochitika zolimbitsa thupi. Mlingo umodzi wokhazikitsidwa ndi insulin, womwe ulipo kwa odwala onse, mulibe. Pafupifupi, kuchuluka kwa insuman Bazal tsiku lililonse ndi 1⁄2-1 IU pa 1 kg iliyonse yakulemera.

Pambuyo pa nthawi yoikidwiratu, wokonzekera endocrinologist ayenera kupereka malingaliro ake momwe angalowe, nthawi yanji komanso momwe angachitire ndi kuchuluka kwa glycemic.

Ngati munthu wodwala matenda ashuga asanachitike Insuman Bazal adagwiritsa ntchito mtundu wina wa insulin

Mtengo wa pafupifupi: fl. (5 ma PC.) - 1492 rub., Sp.r. "SoloStar" ndi cartridge. (Ma PC 5.) - 1294 rub.

Kusamutsa kuchokera ku mtundu wina wa mankhwala a hypoglycemic kuyenera kuchitika moyang'aniridwa ndi dokotala. Mungafunike kusintha mlingo wa jakisoni. Ngati izi zisanachitike, odwala matenda ashuga adalowetsa insulin yomwe idachokera ku nyama, kuchuluka kwa insuman Bazal kumatha kuchepetsedwa, makamaka kwa iwo omwe adayikidwa mankhwala ochepa, komanso kwa odwala omwe ali ndi chiopsezo chowonjezeka cha hypoglycemia. Kufunika kosintha mlingo kumatha kuchitika nthawi yomweyo ndikusintha kapena kupanga mawonekedwe angapo milungu ingapo.

Mukayamba maphunziro atsopano, muyenera kuwunika mosamala kusinthasintha kwa glycemia. Anthu odwala matenda ashuga omwe kale amagwiritsa ntchito Mlingo waukulu wa insulin chifukwa cha kupezeka kwa ma antibodies ayenera kuyang'aniridwa ndi achipatala kwakanthawi.

Zina mwa kukonza Mlingo wa insulin

Ndi kuwongolera bwino glycemia, chidwi chowonjezereka cha mankhwalawa chitha kuchitika, chomwe chingapangitse kuchepa kwa insulin mthupi. Kuphatikiza apo, kukonza kuyenera kuchitika ndi:

• Kusintha kwa thupi
• Moyo watsopano (kuphatikizapo zakudya, zolimbitsa thupi, ndi zina).
• Zinthu zina zomwe zimapangitsa chidwi cha kupezeka kwa hypo- kapena hyperglycemia.

Zomwe zimagwiritsidwa ntchito pa mankhwalawa m'magulu ena a odwala matenda ashuga:

• Okalamba: kufunikira kwa thupi la mahomoni kumatha kuchepa, kotero kuyambika kwa maphunzirowo, kusintha kwa kuchuluka kwa mankhwalawa kuyenera kuchitika mosamala kwambiri kuti pasakhumudwe kugwa kwa glucose ndi mikhalidwe yotsatira.
• Odwala omwe ali ndi vuto la impso ndi / kapena kulephera kwa chiwindi: pali kuchepa kwa zofunika za insulin.

Pa nthawi yoyembekezera komanso yoyamwitsa

Amadziwika kuti insulini siyitha kudutsa chotchinga. Kugwiritsa ntchito Insuman Bazal GT pochitika kuti mayi apitirizebe kupitilira kumatha kupitilizidwa.

Nthawi yonse ya gestation, ndikofunikira kwambiri kuyendetsa bwino matenda a glycemic. Ngati matenda a shuga adapezeka musanatenge pathupi kapena kukhazikitsidwa panthawi yopaka gestational, endocrinologist atha kukupatsirani mankhwala atatha kupenda zomwe zimagwirizanitsidwa ndi chizindikiro cha shuga.

Kufunika kwa insulin mthupi kumatha kuchepa kumayambiriro kwa mimba kenako kumawonjezeka nthawi ya 2nd ndi 3. Mu nthawi ya kubadwa komanso nthawi yomweyo, kubadwa kwa insulin kumachepa, komwe kumayambitsa hypoglycemia. Chifukwa chake, pakuwongolera glycemia, kuwunika mayendedwe a glucose ndikofunikira.

Ngati mayi akukonzekera kukhala mayi, ayenera kudziwitsa adotolo ake za izo.

Pa mkaka wa m`mawere, palibe zolepheretsa mankhwala insulin. Malinga ndi malingaliro a madotolo, kukonza kwa insulin ndi zakudya za tsiku ndi tsiku zitha kuperekedwa kwa mayi woyamwitsa.

Contraindication ndi Kusamala

Insuman Bazal sayenera kugwiritsidwa ntchito ngati wodwala ali ndi:

• Kuchuluka kwa chidwi kapena kusalolera kwathunthu pazigawo za mankhwala
• Hypoglycemia.

Mankhwalawa sanapangidwe kuti azigwiritsidwa ntchito ndi kulowetsedwa, mapampu a insulin.

Contraindication wachibale, momwe kuikidwa kuyenera kuchitidwa mosamala, ndipo njira ya chithandizo imayang'aniridwa nthawi zonse ndi madokotala, ndi:

• Zosakwanira impso ndi / kapena chiwindi ntchito okalamba odwala matenda ashuga
• CCC zosokoneza
• Proliferative retinopathy.

Insulin Bazal: mikhalidwe yayikulu

Awa ndi mankhwala a hypoglycemic omwe amagwiritsidwa ntchito ngati mtundu wa matenda a shuga a insulin. Gawo lomwe limagwiritsa ntchito mankhwalawa ndi insulin yaumunthu.

Mankhwalawa ndi kuyimitsidwa koyera kwa subcutaneous makonzedwe. Ndi gawo la gulu la insulin ndi mawonekedwe awo, omwe ali ndi zotsatira zapakati.

Insulin Insuman Bazal GT imagwira ntchito pang'onopang'ono, koma zotsatira zake pambuyo pakukonzekera zimatenga nthawi yayitali. Kupendekera kwakukulu kwambiri kumachitika patatha maola 3-4 kuchokera pakubayidwa ndipo kumatha mpaka maola 20.

Mfundo za mankhwalawa ndi motere:

1. Imachepetsa glycogenolysis ndi glyconeogeneis,
2. amachepetsa kuchuluka kwa shuga m'magazi, amachepetsa mphamvu ya kagayidwe kachakudya, ndikuthandizira kusintha kwa anabolic,
3. tikuletsa lipolysis,
4. imalimbikitsa kupangika kwa glycogen mu minofu, chiwindi ndi kusamutsa glucose pakati pa maselo.
5. amalimbikitsa kutulutsa kwa potaziyamu kupita ku maselo,
6. imayambitsa kaphatikizidwe ka mapuloteni komanso njira yoperekera amino acid ku cell,
7. Amakhala ndi mawuwa mu chiwindi ndi minofu ya adipose,
8. amalimbikitsa kugwiritsidwa ntchito kwa pyruvate.

Mwa anthu athanzi, theka la moyo wa mankhwala kuchokera m'magazi amatenga mphindi 4 mpaka 6. Koma ndi matenda a impso, nthawi imachuluka, koma izi sizikhudza kagayidwe kachakudya ka mankhwala.

Malangizo ogwiritsira ntchito mankhwalawa

Dokotala wokhazikika ndi amene ayenera kusankha kuchuluka kwa kukonzekera kwa insulini potengera momwe moyo wa wodwalayo ulili, zochita ndi zakudya. Komanso kuchuluka kwake kumawerengedwa pamaziko a glycemia ndi carbohydrate metabolism.

Wapakati tsiku lililonse mlingo kuyambira 0,5 kuti 1.0 IU / pa 1 makilogalamu kulemera. Pankhaniyi, 40-60% ya mlingo amaperekedwa chifukwa cha insulin yayitali.

Ndizofunikira kudziwa kuti mukasintha kuchokera ku insulin ya zinyama kupita kwa anthu, kuchepetsa mlingo kungafunike. Ndipo ngati kusintha kwapangidwa kuchokera ku mitundu ina ya mankhwala, ndiye kuti kuyang'anira kuchipatala ndikofunikira. Kusamalidwa makamaka kuyenera kuchitika kuti kuwunikire kagayidwe kazachilengedwe m'masiku 14 atatha kusinthaku.

Insulin Bazal imayendetsedwa pansi pa khungu pakatha mphindi 45-60. musanadye, koma nthawi zina wodwalayo amapatsidwa jakisoni wa mu mnofu. Ndikofunika kudziwa kuti nthawi iliyonse komwe jekeseni adzayambitsa ayenera kusinthidwa.

Aliyense wodwala matenda ashuga ayenera kudziwa kuti insulini ya basal siigwiritsa ntchito mapampu a insulini, kuphatikizira okhazikika. Pankhaniyi, iv makonzedwe a mankhwala amatsutsana.

Kuphatikiza apo, mankhwalawa sayenera kukhala osakanikirana ndi ma insulin omwe amakhala ndi mawonekedwe osiyanasiyana (mwachitsanzo, 100 IU / ml ndi 40 IU / ml), mankhwala ena ndi ma insulin a nyama. Masautso a Basal Insulin mu vial ndi 40 IU / ml, kotero muyenera kugwiritsa ntchito syringes zapulasitiki zokha zomwe zimapangidwira mwachindunji kuzungulira uku kwa mahomoni. Komanso, syringe siyenera kukhala ndi zotsalira za insulin yakale kapena mankhwala ena.

Musanayambe kudya yankho kuchokera ku vial, tsegulani ma CD ndikuchotsa pulasitiki. Koma, choyamba, kuyimitsidwa kuyenera kugwedezedwa pang'ono kuti isandulike oyera ndi mawonekedwe osasinthika.

Ngati mutagwedeza mankhwalawa ukakhalabe wowonekera kapena kuti pali zigamba kapena matope m'madzi, ndiye kuti mankhwalawa ndi osavomerezeka. Pankhaniyi, ndikofunikira kutsegula botolo lina, lomwe lidzakwaniritsa zonsezi pamwambapa.

Asanatolere insulini kuchokera phukusi, pamalowetsedwa mpweya wocheperako, kenako umayikidwa mu vial. Kenako phukusi limasinthidwa ndi syringe ndipo gawo lina la yankho limasonkhanitsidwa mmenemo.

Musanapange jakisoni, mpweya uyenera kumasulidwa ku syringe. Kuphatikiza khola kuchokera pakhungu, singano imayikidwamo, kenako yankho lake limalowetsedwa pang'onopang'ono. Pambuyo pake, singanoyo imachotsedwa mosamala pakhungu ndipo swab ya thonje imakankhidwira kumalo a jekeseni kwa masekondi angapo.

Kuunika kwa odwala matenda ashuga ambiri kumatsimikizira kuti ma insulinge ndiwotsika mtengo, koma ndizovuta kugwiritsa ntchito. Masiku ano, kuti athandize njirayi, peniresi yapadera imagwiritsidwa ntchito. Ichi ndi chipangizo choperekera insulin chomwe chitha kupitilira zaka zitatu.

Cholembera cha basal GT chimagwiritsidwa ntchito motere:

• Muyenera kutsegula chipangizocho, gwiritsitsani gawo lawo lamakina ndikukokera kapu kumbali.
• Wonyamula cartridge samachotsedwa pamakina ogwiritsa ntchito.
• Katoni imayikidwa mu chogwirizira, chomwe chimasungunuka kumbuyo (njira yonse) mpaka gawo laumakina.
• Asanayankhe yankho pansi pakhungu, cholembera chakecho chimayenera kutenthetsedwa pang'ono m'manja.
• Zovala zamkati ndi zamkati zimachotsedwa mosamala mu singano.
• Kwa katoni watsopano, jekeseni imodzi ndi magawo anayi; kuti muyike, muyenera kukoka batani loyambira ndikuzungulira.
• Singano (4-8 ml) ya cholembera imayikidwa molunjika pakhungu, ngati kutalika kwake ndi 10-12 mm, ndiye kuti singano imayikidwa pakona pa madigiri 45.
• Chotsatira, dinani modekha batani loyambalo la chipangizocho ndikulowetsa kuyimitsidwa mpaka kuwonekera, kuwonetsa kuti cholembera chatsika mpaka zero.
• Pambuyo pake, dikirani masekondi 10 ndikutulutsa singano kuchokera pakhungu.

Tsiku lokhazikitsidwa koyimitsidwa koyenera liyenera kulembedwa pamapepala olembedwa. Ndizofunikira kudziwa kuti mutatsegula kuyimitsidwa kumatha kusungidwa pamtunda wopitilira madigiri 25 kwa masiku 21 m'malo a mdima ndi ozizira.

Zotsatira zoyipa, contraindication, bongo

Insuman Bazal GT ilibe zotsutsana zambiri komanso zoyipa. Nthawi zambiri zimachitika kuti munthu payekha asatsutsidwe. Pankhaniyi, edema ya Quincke, kupuma movutikira kumayamba, ndipo totupa timawoneka pakhungu ndipo nthawi zina limayakasa.

Zotsatira zina zoyipa zimachitika makamaka ndi chithandizo chosayenera, kusatsatira malangizo azachipatala kapena ulesi wa insulin. Muzochitika izi, wodwala nthawi zambiri amakhala ndi hypoglycemia, yomwe imatha kutsatiridwa ndi zovuta za NS, migraines, ndi mawu opuwala, masomphenya, kusazindikira komanso kukomoka.

Komanso, ndemanga za anthu odwala matenda ashuga akuti ngati atakhala ndi mlingo wochepa, kudya mosavutikira ndikulumpha jakisoni, hyperglycemia ndi matenda ashuga angachitike. Izi zimachitika limodzi ndi kupuma, kugona, kukomoka, ludzu, komanso kusowa kudya.

Kuphatikiza apo, khungu pakhungu la jakisoni limayakasa, ndipo mikwingwirima nthawi zina imayamba. Kuphatikiza apo, kuwonjezereka kwa gawo la anti-insulin antibodies ndikotheka, chifukwa cha chomwe hyperglycemia imatha kukhazikika.Odwala ena amakumana ndi masinthidwe oyambukira ndimatumbo omwe amapanga thupi.

Ngati insulin yambiri, hypoglycemia ya zovuta zosiyanasiyana akhoza kukhala. Ndi mawonekedwe ofatsa, wodwalayo akazindikira, ayenera kumamwa chakumwa chokoma kapena kudya zomwe zili ndi chakudya. Pofuna kutaya chikumbumtima, 1 mg ya glucagon imabayidwa intramuscularly, osagwiritsa ntchito njira yothetsera shuga (30-50%) imagwiritsidwa ntchito.

Ndi hypoglycemia wa nthawi yayitali kapena wowopsa, pambuyo pa kukhazikitsidwa kwa glugagon kapena glucose, kulowetsedwa ndi njira yofooka ya shuga ndikulimbikitsidwa, komwe kungapewe kuyambiranso.

Odwala ambiri amagonekedwa m'chipatala kuti azimuyang'anira.

Za mawonekedwe akumasulidwa ndi kapangidwe kake

Mankhwalawa ndi mtundu wa insulin ya anthu nthawi yayitali yoti awonekere. Pazomwe zimapangidwa, ndikuyimitsidwa komwe kumapangidwa kuti kakhazikitsidwe ka subcutaneous. Mtundu wake ndi loyera kapena pafupifupi loyera, pomwe Bazal, yowonetsedwa ngati insulini, imabalalika mosavuta komanso mwachangu.

Ngati tizingolankhula za kapangidwe kake, gawo lalikulu ndi lotchedwa insulin-isophan. Umu ndi mtundu wa munthu wa mahomoni omwe amapezeka ndi ma genetic engineering. Palinso zinthu zina zothandiza, monga:

• protamine sulfate,
• metacresol (kapena m-cresol),
• phenol
• zinc chloride ndi ena ambiri.

Zokhudza mawonekedwe a "Basal"

Insulin yofotokozedwayo imapezeka ngati momwe mungakhalire ma cartridge kapena ngati mbale. Chifukwa cha kapangidwe kake, zomwe zimagwira ntchito, Bazal imatha kutengedwa ngati imodzi mwazinthu zabwino kwambiri za insulin za nthawi yayitali yowonekera yomwe ikupezeka lero.

Zokhudza zotsatira zamankhwala

Hormone iyi imakhala ndi chindunji kwambiri pakuchepetsa shuga m'magazi, komanso imakhala ndi zotsatira zabwino pazotsatira za anabolic komanso zimachepetsa zotsatira za catabolic. Kuphatikiza apo, ndi Bazal yomwe imatha kuwonjezera kufalikira kwa glucose mkati mwa maselo aliwonse ndi kaphatikizidwe ka glycogen mu minofu ndi chiwindi.

Zotsatira zina zapadera za pharmacological zimaphatikizapo kugwiritsa ntchito bwino kwa pyruvate, kuletsa kwa glycogenolysis ndi gluconeogeneis.

Kuphatikiza apo, timadzi timene timalumikizitsa lipogenesis m'chiwindi ndi ma adipose, komanso timalepheretsa lipolysis. Zimathandizira kuthamanga kwa ma amino acid osiyanasiyana m'malo a cell, komanso kupanga mapuloteni, omwe, okha, amathandizira kuwonjezeka kwa kudya kwa potaziyamu mu selo iliyonse.

Monga mukudziwa, "Bazal" ndi insulin ya nthawi yayitali yowonekera ndi kuyambitsa kwadongosolo la ntchito. Pambuyo pakubaya kwa subcutaneous, mphamvu ya mtundu wa hypoglycemic imadziwonekera mkati mwa ola limodzi, imafikira maola atatu kapena anayi, ndipo imatha osachepera 11 ndi kupitirira maola 20.

Zokhudza mlingo

Momwe mungakhazikitsire mlingo wa "Basal"?

Pankhani ya Bazal insulin, mulingo woyenera, umayenera kuyang'aniridwa mosamala. Chifukwa chake, kuchuluka kwakukulu kwa glucose m'magazi, komanso ndalama zomwe zimakhala ndi insulin zomwe zimayenera kugwiritsidwa ntchito, makamaka, mlingo wa algorithm, makamaka:

1. Mlingo
2. nthawi yakukhazikitsa iyenera kuzindikiridwa ndi kukonza payokha.

Izi zimachitika mwanjira yoti azikhala mokwanira ndi chakudya, kuchuluka kwake komanso kuchuluka kwa zochita zolimbitsa thupi ndi wodwala yemwe ali ndi matenda ashuga, zomwe sizofunikanso.

Tiyenera kukumbukira kuti malamulo okhazikika a mlingo wa insulin sapezeka. Nthawi yomweyo, avareji ya mahomoni tsiku lililonse imachokera ku 0,5 mpaka 1 ME pa kilogalamu ya thupi, pomwe insulin yokhala ndi anthu yotenga nthawi yayitali imakwana 40 mpaka 60% ya kuchuluka kwa insulini patsiku.

Odwala matenda ashuga amalangizidwa kuti apereke malangizo ndi zofunikira zonse pafupipafupi pofufuza kuchuluka kwa shuga, komanso malingaliro ena okhudzana ndi kusintha kwamtundu uliwonse malinga ndi zakudya kapena algorithm ya insulin. Zonsezi ndizofunikira kwambiri kuti pakhale mtundu uliwonse wa matenda ashuga.

Zokhudza kusintha kuchokera ku mitundu ina ya insulin

Pokonza matenda ashuga kuchokera ku mtundu wina wa insulin kupita ku wina, mwina pangafunike kukonza ma algorithm omwe akupereka Mlingo wa timadzi timeneti.

Mwachitsanzo, pakusintha kuchokera ku insulin ya chiberekero cha umunthu kupita ku mahomoni amunthu komanso m'malo ena ambiri ofanana.

Pambuyo pakusintha kuchokera ku mahomoni osachokera kwa munthu kupita ku insulin ina, zingakhale zofunikira kuchepetsa kwambiri Bazal. Makamaka, izi zimakhudza odwala omwe kale ankalandira chithandizo cha mankhwala ochepetsa magazi. Zidzakhudzanso odwala matenda ashuga omwe amakonda kupangika kwa hypoglycemia ndi omwe kale amafunikira Mlingo wofunikira wa mahomoni chifukwa chokhudzana ndi kukhalapo kwa ma antibodies aliwonse a insulin.

Chifukwa chiyani ndikufunika kuchepetsa mlingo?

Kuphatikiza apo, kufunika kosintha, kapena m'malo mwake, kuchepetsedwa kwa mankhwalawa, kumatha kupezeka nthawi yoyamba kugwiritsa ntchito mtundu watsopano wa insulin kapena kupangika mwadongosolo milungu ingapo.

About Kuyamba

Bazal insulin imaperekedwa jekeseni kwambiri pakhungu kwa mphindi 45-60 musanadye. Kukula kwa jakisoni mkati mwa gawo limodzi la jakisoni imodzi kuyenera kusinthidwa nthawi iliyonse.

Kusintha kwa gawo loyambitsa mahomoni (mwachitsanzo, kuchokera ku gawo lina la m'mimba kupita m'chiuno) kuyenera kuchitika pokhapokha atakakumana ndi katswiri. Izi ndichifukwa choti mayamwidwe a insulin ndipo, monga chotulukapo chake, zotsatira za kuchepetsa kuchuluka kwa shuga m'magazi zitha kukhala zosiyana kwambiri. Zimatengera malo oyikirapo, monga tafotokozera kale.

Ndikofunika kukumbukira kuti Bazal siyikulimbikitsidwa kuti mugwiritse ntchito mapampu a insulini osiyanasiyana, kuphatikizapo ophatikizika. Chofunika kwambiri, musaiwale kuti kuphatikiza kwa mankhwala osokoneza bongo sikumachotsedwa kotheratu. Kuti mugwiritse ntchito moyenera, singano yosalala ndi insulini, yogulidwa kokha ku sitolo kapena shopu yapadera, sizofunikira.

Zotsatira zoyipa

Bazal insulin imatsimikiziridwa ndi ochepa zotsatira zoyipa, komabe, adakalipo. Tikukamba za hypoglycemia, yomwe imapangika, kukhala yachilengedwe kwathunthu chifukwa cha kuchuluka kwakukulu kwa mulingo.

Zotsatira zake, zizindikiro za neuropathic, mwachitsanzo, kupweteka kapena chikomokere, zimatha kupanga bwino.

Ndi kuchepa mwadzidzidzi kwa ndende ya magazi, mapangidwe oopsa a hypokalemia, komwe ndi kuphatikizika kwa mtima ndi mtima, komanso kupezeka kwa matenda otupa. Komabe, izi zimachitika kawirikawiri.

Kodi zimatheka?

Mawonekedwe a mziwsi omwe amadutsa mwachangu siwachilendo. Zoterezi zitha kunenedwa za kukwera kwadzidzidzi kwa kuthamanga kwa magazi. Ndizotheka kuimitsa pakumwa mankhwala omwe amatha kuphatikizidwa mosamala ndi insulin.

Kuchita mankhwala osokoneza bongo

Pa nthawi ya insulin, Insuman Bazal GT iyenera kukumbukiridwa kuti ikaphatikizidwa ndi mankhwala ena, kusintha kwa zotsatira za hypoglycemic kapena kusokoneza kwamankhwala ena kwamankhwala ena kumachitika:

• Mphamvu ya Insuman's hypoglycemic imakonzedwa ndikukula ngati ikuphatikizidwa ndi mankhwala ochepetsa shuga a pakamwa, ma AIn inhibitors, iMAO, Disoprimide, salicylates, anabolics, mankhwala omwe ali ndi mahomoni achimuna, Fluoxetine, Fenfluramine, Ifosfamide, sulfonamides, Amphetamine ndi tetetamine.
• Kuphatikizidwa ndi GCS, mankhwala okodzetsa, corticotropin, Danazole, glucagon, mahomoni (estrogens, gestagens), sympathomimetics, zinthu za chithokomiro, zotuluka za phenothiazine, barbiturates ndi mankhwala ena onse zimachepetsa mphamvu ya insulin.
• Mukaphatikizidwa ndi BAB, Clonidine, mchere wa lithiamu, zochita za Insuman Bazal ndizosatheka kuneneratu: zotsatira za hypo- kapena hyperglycemic zingayambike.
• Ethanol amachita pakukonzekera insulini komanso mosakonzekera: zotsatira za Insuman zitha kuchuluka kapena kuchepa. Tiyenera kudziwa kuti ngati wodwalayo achepetsa thupi, ndiye kuti amamwa zakumwa zoledzeretsa kapena mankhwala osokoneza bongo, mlingo wake umatha kutsika kwambiri, womwe ungathe kuwononga thanzi komanso thanzi la munthu wodwala matenda ashuga.

About yosungirako ndi contraindication

Zomwe zimakhudzana ndi kusungidwa kwa Bazal insulin ndi izi:

• malo osatheka ndi ana
• Kutetezedwa kwathunthu ku kuwala ndi kuwala kwa dzuwa,
• motere, kutentha kwa boma kuyenera kukhala kuchokera madigiri awiri mpaka asanu ndi atatu.

Ndikofunikanso kupewa kuzizira, chifukwa izi zimakhudza kuwonongeka kapena kusintha kwathunthu kwa mtundu wa mankhwalawo. Moyo wa alumali ndi zaka ziwiri kuyambira tsiku lopangira mankhwalawa. Pambuyo pakutsegulira, ma ampoule omwe amayimitsidwa amatha kusungidwa osaposa miyezi inayi m'malo ozizira komanso amdima.

Polankhula za zotsutsana, ziyenera kudziwika monga milandu ya hypoglycemia komanso kuchuluka kwakukhudzika kwa mphamvu ya mahomoni kapena zinthu zina zilizonse zothandizira zomwe zili pamndandanda wazinthu. Muyenera kuganizira kuchepetsa kuchuluka kwa omwe ali ndi vuto la impso ndi chiwindi komanso omwe ali ndi ukalamba.

Milandu imeneyi siyiyenera kuonedwa ngati yolakwira, komabe, kugwiritsidwa ntchito kwa Bazal insulin kuyenera kukhala kovomerezeka. Kupanda kutero, kugwiritsidwa ntchito kwake kungakhale koopsa kwa aliyense wa odwala matenda ashuga. Komabe, kutengera malamulo onse, mtundu wa insulin womwe ungapatsidwe udzakhala wothandiza kwambiri pa matenda ashuga.

Insuman Bazal GT ndi ya masanjidwe obadwa nawo amtundu wa nthawi yayitali. Imapezeka kwa E. coli strain K12 135 pINT90d. Zomwe zimagwira ndi insulin-isophan. Amapezeka mu mawonekedwe a kuyimitsidwa kwa jakisoni pansi pa khungu.

Bongo

Kukhazikitsidwa kwa Insuman Bazal yambiri yodya chakudya kapena mphamvu yowonjezereka kumabweretsa chitukuko cha hypoglycemia ya zovuta zosiyanasiyana.

Ndi matenda otchulidwa pang'onopang'ono, wodwala matenda ashuga amatha kuthetsa vuto la hypoglycemia mwa kudya chakudya chamagulu.

Woopsa mitundu ya bongo, pamene hypoglycemia zinachititsa kuti asiye kuzindikira, amene, kupweteka kapena mitsempha, wodwala amafunika kuthandizidwa. Milandu iyi, kulowetsedwa kwa kulowererapo kwa dextrose kumalimbikitsidwa, mwina kulowetsedwa kudzera m'mitsempha kapena m'magazi. Ngati hypoglycemia imachitika mwa mwana, ndiye kuchuluka kwa zothetsera izi kumawerengedwa molingana ndi kulemera kwa thupi.

Pambuyo pakukula kwa glycemia, kuchepa kwakanthawi kwa glucose kumatha, chifukwa chake, wodwalayo amapatsidwa chakudya choyenera cha zakudya zamatumbo.

Ngati vuto lalikulu pambuyo pa bongo litenga nthawi yayitali kwambiri kapena kudziwonetsera kwambiri, ndiye kuti wodwalayo angafotokozedwe mobwerezabwereza kwa dextrose m'munsi ndende kuti tipewe kuchitika.Ndikofunikira kwambiri kuyang'anira kuchuluka kwa shuga mwa ana aang'ono, popeza amatha kutengera mitundu yambiri ya hypoglycemia.

Nthawi zina, wodwalayo amagonekedwa m'chipatala kuti apenye kuwonedwa ndi kuwongoleredwa.

Funso lothana ndi mankhwalawo ndi mtundu wina wa insulin lingathe kungosankhidwa ndi endocrinologist.

Marvel L.S. (India)

Mtengo wapakati: 1 fl. 40 IU (10 ml) - 535 rub., 1 vial. 100 IU (10 ml) - 536 rub., Cartr. 100 IU (ma PC 5.) - 1,080 ma ruble.

Mankhwala osokoneza bongo amtundu 1 komanso matenda ashuga a 2. Amapangidwa pamaziko a insulin ya anthu omwe amapezeka pakati. Wopezeka mu insulin ya 40 kapena 100 IU.

Njira yoyendetsera ndi kuchuluka kwa jakisoni imatsimikiziridwa ndi mtundu komanso kuopsa kwa matenda ashuga, concomitant pathologies ndi zina za wodwalayo.

• Sikovuta kupeza mlingo woyenera.
• Sikuti nthawi zonse zimathandiza kuchepetsa shuga.

Cholinga cha shuga m'magazi, kukonzekera kwa insulin komwe kumayenera kugwiritsidwa ntchito, njira ya insulin dosing (mlingo ndi nthawi ya makonzedwe) iyenera kutsimikizika ndikusintha payekhapayekha kuti mugwirizane ndi chakudya, mulingo wakuchita zolimbitsa thupi komanso moyo wa wodwalayo.

Palibe malamulo oyendetsedwa bwino a insulin. Komabe, pafupifupi tsiku lililonse insulin ndi 0,5-1 IU / kg / tsiku, ndipo munthu amene amakhala ndi insulin nthawi yayitali 40-60% ya kuchuluka kwa insulin tsiku lililonse.

Dokotala amayenera kupereka malangizo ofunikira kuti azindikire kuchuluka kwa shuga m'magazi, komanso apereke malangizo oyenera pazosintha zilizonse m'zakudya kapena muyezo wa insulin.

Kusintha kuchokera ku mtundu wina wa insulin kupita ku Insuman ® Bazal GT

Posamutsa wodwala kuchokera ku mtundu wina wa insulin kupita ku ina, kuwongolera kwa insulin dosing regimen kungafunike: mwachitsanzo, pakusintha kuchokera ku insulin yochokera ku nyama kupita ku insulin yaumunthu, kapena mukasintha kuchokera ku insulin yomwe munthu akukonzekera ndikupita ku regimen. kuphatikiza insulin.

Pambuyo pakusintha kuchokera ku insulin yochokera ku nyama kupita ku insulin ya anthu, mwina pangafunike kuchepetsa kuchuluka kwa insulin, makamaka kwa odwala omwe kale anali ndi zovuta zamagazi, odwala omwe ali ndi chizolowezi chokhala ndi hypoglycemia, mwa odwala omwe kale amafuna kuchuluka kwa insulin yayikulu chifukwa cha ndi kukhalapo kwa ma antibodies ku insulin. Kufunika kosinthira kwa mlingo (kuchepetsa) kumatha kuchitika mukangosintha mtundu watsopano wa insulin kapena kuyamba pang'onopang'ono milungu ingapo.

Mukasintha kuchokera ku mtundu wina wa insulini kupita ku wina kenako m'milungu yoyamba yotsatira, kuyang'aniridwa mosamala kwa shuga wamagazi ndikulimbikitsidwa. Odwala omwe amafuna kwambiri Mlingo wa insulin chifukwa cha antibodies, tikulimbikitsidwa kusinthana ndi mtundu wina wa insulin moyang'aniridwa ndi achipatala kuchipatala.

Kusintha kowonjezera kwa insulin

Kuwongolera kagayidwe ka metabolic kumatha kuyambitsa chidwi cha insulini, zomwe zingapangitse kuchepa kwa kufunika kwa insulin.

Kusintha kwa mlingo kungafunikenso ngati:

Zosintha pamlingo wa wodwala,

Kusintha kwamoyo (kuphatikizapo zakudya, kuchuluka kwa zolimbitsa thupi, ndi zina).

Nthawi zina zomwe zimapangitsa kuti chiwopsezo cha hypo- kapena hyperglycemia chiwonjezeke.

Mlingo wampingo wamagulu apadera odwala

Okalamba. Kwa okalamba, kufunika kwa insulini kumatha kuchepa. Ndikulimbikitsidwa kuti kuyambitsidwa kwa chithandizo, kuyamwa kwa mankhwalawa ndikusankha mankhwalawa okalamba omwe ali ndi matenda osokoneza bongo kuchitike mosamala kuti asagwere.

Odwala omwe ali ndi chiwindi kapena aimpso kulephera. Odwala omwe ali ndi vuto la hepatic kapena aimpso, kufunika kwa insulin kungachepe.

Kukhazikitsidwa kwa mankhwala Insuman ® Basal GT

Insuman ® Basal GT nthawi zambiri imaperekedwa mozama s / c 45-60 mphindi asanadye. Tsamba la jakisoni mkati mwa jekeseni lomwelo limayenera kusinthidwa nthawi iliyonse. Kusintha gawo la kayendetsedwe ka insulin (mwachitsanzo, kuyambira pamimba mpaka ntchafu) kuyenera kuchitika pokhapokha mukaonana ndi dokotala, chifukwa mayamwidwe a insulin, motero, mphamvu yochepetsera kuchuluka kwa shuga m'magazi ingasiyane malingana ndi dera loyang'anira (mwachitsanzo, pamimba kapena ntchafu).

Insuman ® Basal GT sagwiritsidwa ntchito m'mapampu amtundu wa insulin (kuphatikizapo omwe adalowetsedwa).

Mu / pakubwezeretsa mankhwalawa asiyidwa kwathunthu!

Osasakaniza Insuman ® Basal GT ndi insulin ya ndende ina, ndi insulin ya nyama, insulin analogs kapena mankhwala ena.

Insuman ® Bazal GT ikhoza kusakanizika ndi magulu onse amakono a insulin-aventis. Insuman ® Basal GT siyenera kusakanikirana ndi insulin yomwe cholinga chake amagwiritsidwe ntchito pamapampu a insulin.

Kumbukirani kuti kuchuluka kwa insulini ndi 100 IU / ml (kwa ma ml 5 kapena ma 3 ml makatiriji), motero ndikofunikira kugwiritsa ntchito syringes zapulasitiki zokha zomwe zimapangidwira insulin iyi ya insulin ngati mugwiritsa ntchito mbale, kapena OptiPen Pro1 kapena ClickSTAR syringe pens nkhani ya kugwiritsa ntchito makatoniji. Syringe ya pulasitiki siyenera kukhala ndi mankhwala ena aliwonse kapena zotsalira zake.

Pamaso gawo loyambirira la insulin kuchokera pambale, chotsani kapulasitiki (kukhalapo kwa kapuyo ndi umboni wa vial wosatsutsana). Kuyimitsidwa kuyenera kusakanizidwa bwino nthawi isanakhazikitsidwe, ndipo palibe chithovu chomwe chingapangidwe. Izi zimachitika bwino ndikutembenuza botolo, ndikuligwirizira kumbali yayikulu pakati pa manja. Pambuyo posakanikirana, kuyimitsidwa kumayenera kukhala kosasinthasintha komanso mtundu wamiyala yoyera. Kuyimitsidwa sikungagwiritsidwe ntchito ngati kuli ndi mtundu wina, i.e. ngati ikhala yowonekera bwino kapena masamba kapena mapanga apanga madziwo, pansi kapena kukhoma kwa vial. Zikatero, muyenera kugwiritsa ntchito botolo lina lomwe likugwirizana ndi zomwe zili pamwambapa, ndipo muyenera kudziwitsa dokotala.

Asanatenge insulini kuchokera ku vial, mpweya wofanana ndi mankhwala omwe amaperekedwa ndi insulin umayamwa mu syringe ndikujowina mu vial (osalowa madzi). Kenako vala yokhala ndi syringe imasinthidwa mozungulira ndi syringe ndipo kuchuluka kwa insulini kumatengedwa. Pamaso jakisoni, chotsani thovu lakumanzere mu syringe. Khungu limatengedwa pamalo a jakisoni, singano imayikidwa pansi pakhungu, ndipo insulin imayamwa pang'onopang'ono. Pambuyo pa jekeseni, singano imachotsedwa pang'onopang'ono ndipo tsamba lamalowo limakanikizidwa ndi swab ya thonje kwa masekondi angapo. Tsiku lokhala ndi insulin kit kuchokera pa vial iyenera kulembedwa pa cholembera cha vial.

Pambuyo pakutsegulira, mabotolo amatha kusungidwa pamtunda osapitirira 25 ° C kwa masabata anayi kumalo otetezedwa ku kuwala ndi kutentha.

Musanayikitse cartridge (100 IU / ml) mu cholembera cha sytiit ya OptiPen Pro1 ndi ClickSTAR, ndikofunikira kupirira nawo kwa maola 1-2 kutentha kwa chipinda (jakisoni wa insulin yovunda kwambiri. Pambuyo pake, ndikutembenuza mokoma cartridge (mpaka nthawi 10) kuti mupeze kuyimitsidwa kwapadera. Kathumba kalikonse kophatikizira kamakhala ndi mipira 3 yachitsulo posakaniza mwachangu zomwe zili. Pambuyo pokhazikitsa cartridge mu syringe cholembera, jekeseni iliyonse ya insulin isanachitike, cholembera cha syringe chimasinthidwa kangapo kuti chimuyimitse. Pambuyo posakanikirana, kuyimitsidwa kumayenera kukhala kosasinthasintha komanso mtundu wamiyala yoyera. Kuyimitsidwa sikungagwiritsidwe ntchito ngati kuli ndi mtundu wina, i.e. ngati ikhala yowonekera bwino kapena masamba kapena mapampu apanga madziwo, pansi kapena pansi pa makatoni.Zikatero, muyenera kugwiritsa ntchito cartridge ina yomwe ikukwanira pamwambapa, ndipo muyenera kudziwitsa dokotala. Chotsani zotumphukira zilizonse zamagetsi pamkatikati musanabayidwe (onani Malangizo ogwiritsira ntchito zolembera za OptiPen Pro1 kapena ClickSTAR syringe).

Katoniyo sanapangidwe kuti aphatikize Insuman ® Bazal GT ndi ma insulini ena. Makatoni opanda kanthu sangakwaniritsidwe. Pakuswa phala la syringe, mutha kulowa muyezo wofunika kuchokera pa cartridge pogwiritsa ntchito syringe yachizolowezi. Kumbukirani kuti kuchuluka kwa insulini mu cartridge ndi 100 IU / ml, kotero muyenera kugwiritsa ntchito syringes zapulasitiki zopangidwira insulin. Syringe siyenera kukhala ndi mankhwala ena aliwonse kapena zotsalira zake.

Pambuyo kukhazikitsa cartridge, itha kugwiritsidwa ntchito milungu 4. Ndikulimbikitsidwa kusungidwa pa kutentha osapitirira 25 ° C pamalo otetezedwa ku kuwala ndi kutentha. Mukamagwiritsa ntchito cartridge, cholembera cha syringe sichisungidwa mufiriji (popeza jakisoni wodziwika ndi insulin yovuta kwambiri). Pambuyo kukhazikitsa katiriji watsopano, ndikofunikira kuyang'ana momwe cholembera chikugwirira ntchito musanalowe jekeseni woyamba (onani malangizo a ntchito OptiPenPro 1 kapena ClickSTAR Syringe Pens).

Malangizo ogwiritsira ntchito ndi kusamalira cholembera chodzaza ndi SoloStar ®

Asanayambe kugwiritsa ntchito, cholembera cha syringe chimasungidwa kutentha kwa firiji kwa maola 1-2.

Musanagwiritse ntchito, muyenera kuyang'ana cartridge mkati mwa syringe cholembera mutasakaniza bwino kuyimitsidwa komweko mwa kutembenuza cholembera mozungulira cholowera, ndikuchigwira pakona pakati pa manja. Iyenera kugwiritsidwa ntchito pokhapokha, atasakanikirana, kuyimitsidwa kumakhala kosasinthasintha komanso mtundu wamiyala yoyera. Cholembera sichingagwiritsidwe ntchito ngati kuyimitsidwa mkati mwake mutasakanikirana ndi mtundu wina, i.e. ngati ikhala yowonekera bwino kapena masamba kapena mapampu apanga madziwo, pansi kapena pansi pa makatoni. Zikatero, gwiritsani ntchito cholembera china chosiyana ndikudziwitsa dokotala.

Empty SoloStar ® Syringe Pens siyenera kugwiritsidwanso ntchito ndipo iyenera kutayidwa.

Popewa matenda, cholembera chodzaza chisanachitike chizingogwiritsidwa ntchito ndi wodwala m'modzi ndipo sayenera kusamutsidwira wina.

Kugwira SoloStar ® Syringe chole

Musanagwiritse ntchito cholembera cha SoloStar ®, werengani mosamala zidziwitso pakugwiritsa ntchito.

Zambiri zofunikira pogwiritsa ntchito SoloStar ® Syringe pen

Musanagwiritse ntchito, gwiritsani ntchito singano yatsopano ndi cholembera chonde ndikuyesani mosamala. Ma singano okha omwe amagwirizana ndi SoloStar ® ndi omwe ayenera kugwiritsidwa ntchito.

Malangizo apadera amayenera kuchitika popewa ngozi zokhudzana ndi kugwiritsa ntchito singano komanso mwayi wopatsira matenda.

Musagwiritse ntchito cholembera cha SoloStar ® ngati chawonongeka kapena ngati wodwala alibe chitsimikizo kuti chidzagwira ntchito moyenera.

Ndikofunikira nthawi zonse kukhala ndi cholembera cha SoloStar ® syringe kuti itayike kapena kuwonongeka kwa cholembera cha SoloStar ® syringe.

Malangizo osungira

Ndikofunikira kuphunzira gawo la "Kusungirako" pokhudzana ndi malamulo osungira a cholembera cha SoloStar ®.

Ngati cholembera cha SoloStar ® chikusungidwa mufiriji, chikuyenera kuchotsedwa pamenepo maola 1-2 isanachitike jakisoni wofunikayo kuti kuyimitsidwa kumatenga kutentha kwa chipinda. Makamaka insulini yodziwika bwino imapweteka kwambiri.

Cholembera cha SoloStar ® chogwiritsidwa ntchito chimayenera kuwonongeka.

SoloStar ® syringe cholembera iyenera kutetezedwa kufumbi ndi dothi.

Kunja kwa SoloStar ® Syringe cholembera kumatha kutsukidwa ndikumupukuta ndi nsalu yonyowa.

Osamiza m'madzi, osadzitsuka kapena kupaka cholembera SoloStar ®, chifukwa izi zitha kuwononga.

SoloStar ® Syringe pen imapereka moyenera insulini ndipo ndiotetezeka kugwiritsa ntchito. Zimafunikanso kusamala mosamala. Pewani zochitika zomwe zingawononge cholembera cha SoloStar ® Wodwala akaganiza kuti cholembera cha SoloStar ® syringe chitha kuwonongeka, gwiritsani ntchito cholembera chatsopano.

Gawo 1. Kuwongolera kwa insulin

Ndikofunikira kuyang'ana cholembera pa cholembera cha SoloStar ® kuti mutsimikizire kuti ili ndi insulin yoyenera. Kwa Insuman ® Bazal GT, cholembera cha SoloStar ® ndi choyera ndi batani lobiriwira kuti mupeze jakisoni. Pambuyo pochotsa kapu ya cholembera, ma insulin omwe ali momwemo amawongolera: kuyimitsidwa kwa insulini mutasakanikirana kumayenera kukhala kosasinthasintha komanso mtundu wamiyala yoyera.

Gawo 2. Kulumikiza singano

Ma singano okha omwe amagwirizana ndi cholembera cha SoloStar ® ndi omwe ayenera kugwiritsidwa ntchito.

Pa jakisoni wotsatira, gwiritsani ntchito singano yatsopano yosabala. Pambuyo pochotsa chipewa, singano iyenera kuyikiridwa mosamala pa cholembera.

Gawo 3. Kuchita mayeso a chitetezo (nthawi zonse zimachitika mutasakaniza kuyimitsidwa, onani pamwambapa).

Pamaso pa jekeseni iliyonse, ndikofunikira kuyeserera chitetezo ndikuonetsetsa kuti cholembera ndi singano zimagwira bwino komanso thovu lakum air limachotsedwa.

Pimani mlingo wofanana ndi 2 PIERES.

Zovala za singano zakunja ndi zamkati ziyenera kuchotsedwa.

Ikani cholembera ndi singano kumtunda, ikani pang'onopang'ono katoni ya insulini ndi chala chanu kuti thovu lonse lakumwamba litayendetsedwe ku singano.

Kanikizani bwino batani la jakisoni.

Ngati insulini ikuwonekera pachimake pa singano, izi zikutanthauza kuti cholembera ndi singano zikugwira ntchito moyenera.

Ngati insulini siziwoneka pamphepete mwa singano, ndiye kuti gawo 3 limatha kubwerezedwanso mpaka insulini ikawonekera pamsonga pa singano.

Gawo 4. Kusankhidwa kwa dozi (nthawi zonse kumachitika mutasakaniza kuyimitsidwa, onani pamwambapa)

Mlingo ungayikidwe ndikulondola kwa 1 UNIT: kuchokera pa mlingo wochepa - 1 UNIT kufikira mlingo waukulu - 80 UNITS. Ngati kuli kofunikira kukhazikitsa mlingo wowonjezera wa PISCES 80, jakisoni wa 2 kapena kupitilira uyenera kuperekedwa.

Zenera la dosing likuyenera kuwonetsa "0" mukamaliza kuyesa kwa chitetezo. Pambuyo pake, mlingo wofunikira ukhoza kukhazikitsidwa.

Gawo 5. Mlingo

Wodwala ayenera kudziwitsidwa za njira ya jakisoni ndi katswiri wazachipatala.

Singano iyenera kuyikiridwa pansi pa khungu. Batani la jakisoni liyenera kukanikizidwa kwathunthu. Imasungidwa m'malo ano kwa 10 s mpaka singano itachotsedwa. Izi zimathandizira kuyambitsa mtundu wa insulin kwathunthu.

Gawo 6. Kuchotsa ndi kutaya singano

Mulimonsemo, singano pambuyo pa jekeseni aliyense amayenera kuchotsedwa ndikuchotsedwa. Izi zimathandizira kupewa kuipitsidwa ndi / kapena kutenga kachilomboka, kulowa mu chidebe cha insulin ndi kutulutsa insulin.

Pochotsa ndi kutaya singano, muyenera kusamala mosamala. Malangizo otetezedwa oyenera kuchotsa ndi kuponyera singano (mwachitsanzo, njira yovalira chipewa ndi dzanja limodzi) akuyenera kutsatiridwa kuti muchepetse ngozi zomwe zimakhudza kugwiritsa ntchito singano komanso kupewa matenda.

Mukachotsa singano, tsekani cholembera cha SoloStar ® ndi cap.

Zotsatira za pharmacological

Mlingo wa Insuman Bazal GT ndi 100 IU / ml. Pambuyo makonzedwe pansi pa khungu, amayamba kuchita pang'onopang'ono, akukwaniritsa zotsatira za hypoglycemic mu ola limodzi. Kuchepetsa kwambiri kwa shuga kumachitika patatha maola atatu jakisoni atatha, jakisoniyo amakhala kwa maola 11 mpaka 20. Makina ochitapo kanthu ali ndi mawonekedwe ake:

• Imakhala ndi anabolic, imalepheretsa njira za catabolic, imachepetsa kuchuluka kwa shuga m'magazi a m'magazi.
• Zimathandizira kusamutsa glucose mu cell ndikupanga mbewu za glycogen kuchokera mu hepatocytes ndi minofu, zimalepheretsa glycogenolysis ndi gluconeogeneis, ndikukula kogwiritsa ntchito chomaliza chomaliza - pyruvate.
• Amachepetsa mayendedwe amtundu wa lipolysis, koma amalimbikitsa kapangidwe ka mafuta m'chiwindi.
• Zimawongolera kayendedwe ka amino acid m'maselo a cell ndikupanga mapuloteni.
• Imathandizira kusunthira potaziyamu kudutsa nembanemba kupita ku maselo.

Zotsatira zonse zachilengedwe za insulin insulin basal GT yotsika glycemia.

Gulu la Pharmacotherapeutic:

Zizindikiro zogwiritsidwa ntchito
Insulin-wodwala matenda a shuga. Insuman Rapid GT imawonetsedwa pochiza matenda ashuga komanso ketoacidosis, komanso kuti akwaniritse zolipiritsa za metabolic odwala omwe ali ndi matenda osokoneza bongo a pre-, intra-, ndi postoperative nthawi.

• achina,
• Hypersensitivity reaction insulin kapena mankhwala ena aliwonse othandizira, kupatula milandu yomwe insulin chithandizo ndiyofunika. Zikatero, kugwiritsa ntchito Insuman Rapid GT kumatheka pokhapokha pakumuyang'anirani mosamala ndipo ngati kuli kotheka, kuphatikiza ndi anti-allergen.

Njira zopewera komanso malangizo apadera

N`zotheka mtanda-immunological zochita za anthu insulin ndi insulin ya nyama. Ndi chidwi chowonjezeka cha wodwalayo kuti apange insulin yakuchokera kwa nyama, komanso m-cresol, kulekerera kwa Insuman Rapid GT kuyenera kuwunikiridwa kuchipatala pogwiritsa ntchito mayeso a intradermal. Ngati pakuyesedwa kwa insulin ya insulin ya munthu kumadziwika, zotsatira zake, monga Arthus, ndiye kuti chithandizo china chikuyenera kuyang'aniridwa ndi achipatala. Mwa kuchuluka kwakukulu kwa odwala omwe ali ndi hypersensitivity kupita ku insulin ya nyama, ndizosavuta kusinthana ndi ma insulin aumunthu chifukwa cha mtanda wa immunological wa insulini ya anthu ndi insulin yochokera ku nyama.
Hypoglycemia imatha kukhazikika ngati kuchuluka kwa insulin kudutsa kuposa kufunika kwake.
Pali zisonyezo zina zamankhwala ndizizindikiro zomwe zimayenera kuwonetsa kwa wodwala kapena ena za kutsika kwakuthwa kwa shuga. Izi ndi monga: thukuta la mwadzidzidzi, kuluma, kugwedezeka, kugona, kugona, kusokonezeka kwa tulo, mantha, kukhumudwa, kusayenda bwino, nkhawa, nkhawa paresthesia mkamwa komanso kuzungulira pakamwa, kutsekemera, kupweteka mutu, kusayenda bwino kwa kayendedwe, komanso kusakhalitsa. kusokonezeka kwa mitsempha (kufooka kwa mawu ndi masomphenya, zizindikiro za paralo) ndi zomveka zachilendo. Ndi kutsika kwakukwera m'magulu a shuga, wodwalayo amatha kulephera kudziletsa komanso ngakhale kuzindikira. Zikatero, kuzizira ndi chinyezi pakhungu kumatha kuonedwa, ndipo kupweteka kumawonekeranso.
Odwala ambiri, chifukwa cha mayendedwe a adrenergic, amatha kukhala ndi zotsatirazi, zomwe zikuwonetsa kuchepa kwa magazi: thukuta, chinyezi cha pakhungu, nkhawa, tachycardia (palpitations), kuthamanga kwa magazi, kunjenjemera, kupweteka pachifuwa, kusokonezeka kwa mtima.
Chifukwa chake, wodwala aliyense yemwe ali ndi matenda ashuga komanso kulandira insulin ayenera kuphunzira kuzindikira zizindikiro zosadziwika zomwe ndi chizindikiro cha kukhala ndi hypoglycemia. Odwala omwe amawunika shuga ndi mkodzo pafupipafupi sangakhale ndi hypoglycemia. Kukonda kwambiri hypoglycemia kumatha kulepheretsa wodwala kuyendetsa galimoto komanso kugwiritsa ntchito zida zilizonse. Wodwala amatha kukonza kuchepa kwa shuga komwe adazindikira mwa kudya shuga kapena zakudya zamagulu ochulukirapo. Pazifukwa izi, wodwalayo ayenera kukhala ndi 20 g shuga nthawi zonse.Mokulira kwambiri kwa hypoglycemia, jakisoni wokhazikika wa glucagon akuwonetsedwa (omwe angathe kuchitidwa ndi dokotala kapena antchito oyamwitsa). Pambuyo pakusintha kokwanira, wodwalayo ayenera kudya. Ngati hypoglycemia singathetsedwe mwachangu, ndiye kuti dokotala akuyenera kuyitanidwa mwachangu. Ndikofunikira kudziwitsa dokotala mwachangu za kukula kwa hypoglycemia kuti apange chisankho pakufunika kusintha kwa insulin.
Nthawi zina, zizindikiro za hypoglycemia zimatha kukhala zofowoka kapena kusapezeka. Zochitika zotere zimachitika kwa odwala okalamba, pamaso pa zotupa zamanjenje (neuropathy), odwala matenda amiseche, othandizira ena ndi mankhwala ena (onani "Kuyanjana ndi mankhwala ena"), okhala ndi shuga yochepa kwambiri posintha insulin.
Zotsatira zotsatirazi ndizotheka kuchepa kwambiri kwa shuga m'magazi: insulin yambiri, jakisoni wa insulin wosayenera (mwa odwala okalamba), kusinthana ndi mtundu wina wa insulin, kudumpha chakudya, kusanza, kutsegula m'mimba, kuchita masewera olimbitsa thupi, kuthetsa mavuto, kumwa mowa, ndi matenda omwe amachepetsa kufunika mu insulin (chiwindi chachikulu kapena matenda a impso, kuchepa kwa ntchito ya adrenal cortex, pituitary kapena chithokomiro), kusintha kwa jekeseni (mwachitsanzo, khungu la pamimba, phewa kapena ntchafu), komanso mogwirizana ndi mankhwala ena amatanthauza (onani "Kuyanjana ndi mankhwala ena")
Chiwopsezo cha kukhala ndi hypoglycemia ndi chachikulu pamayambiriro a chithandizo cha insulin, mukasinthira kukonzekera kwina kwa insulin, mwa odwala omwe ali ndi shuga ochepa.
Gulu lowopsa lomwe lili ndi odwala omwe ali ndi zigawo za hypoglycemia komanso kuchepa kwa ziwalo za ziwalo za ziwalo za ziwalo za ziwalo zake ziwalo (ziwalo za ziwalo za ziwalo za ziwalo za ziwalo za ziwalo).
Kulephera kutsatira zakudya, kudumpha jakisoni wa insulin, kuchuluka kwa insulin chifukwa cha matenda opatsirana kapena matenda ena, komanso kuchepa kwa zochitika zolimbitsa thupi kungayambitse kuchuluka kwa shuga m'magazi (hyperglycemia), mwina ndi kuchuluka kwa matupi a ketone m'magazi (ketoacidosis). Ketoacidosis imatha kumatha maola ochepa kapena masiku. Pazizindikiro zoyambirira za metabolic acidosis (ludzu, kukodza pafupipafupi, kulephera kudya, kutopa, khungu lowuma, kupuma kwambiri komanso kuthamanga, chidwi cha acetone ndi glucose mkodzo), chithandizo chamankhwala chofunikira ndichofunikira.
Pakusintha dokotala (mwachitsanzo, nthawi yakuchipatala chifukwa cha ngozi, kudwala panthawi ya tchuthi), wodwalayo ayenera kudziwitsa dokotala kuti ali ndi matenda ashuga.

Mimba komanso kuyamwa

Chithandizo cha Insuman Rapid GT ziyenera kupitilizidwa pa nthawi yapakati. Pa nthawi yoyembekezera, makamaka pambuyo pa trimester yoyamba, kuwonjezereka kwa insulin kuyenera kuyembekezeredwa. Komabe, pambuyo pobadwa, kufunika kwa insulin nthawi zambiri kumatsika, komwe kumabweretsa chiwopsezo chachikulu cha hypoglycemia. Ngati muli ndi pakati kapena mukufuna kubereka, onetsetsani kuti mwadziwitsa dokotala.
Panthawi yoyamwitsa, palibe malamulo oletsa insulin. Komabe, kusintha kwa mlingo ndi kadyedwe kungafunikire.

Mlingo ndi makonzedwe .

Kusankhidwa kwa mlingo wa insulin mwa wodwala kumachitika ndi dokotala payekha, kutengera zakudya, mulingo wakuchita zolimbitsa thupi. Mlingo wa insulin umatsimikizika molingana ndi kuchuluka kwa shuga m'magazi, komanso pamaziko a kuchuluka kwa zochitika zolimbitsa thupi ndi mkhalidwe wa metabolism ya carbohydrate. Chithandizo cha insulin chimafuna kudziphunzitsa koyenera kwa wodwala. Dokotala amayenera kupereka malangizo ofunikira kangati kuti azindikire kuchuluka kwa shuga m'magazi ndipo, mwina, mkodzo, ndikuwapatsanso malangizo oyenera osintha zakudya kapena machitidwe a insulin.
Mlingo wamba wa insulin tsiku lililonse umachokera ku 0,5 mpaka 1.0 ME pa kilogalamu ya thupi la wodwalayo, ndipo 40-60% ya mlingo umagwera insulin yaumunthu yokhala nthawi yayitali.
Posintha kuchokera ku insulin ya nyama kupita ku insulin ya anthu, kuchepetsedwa kwa insulin kungafunike.Kusintha kuchokera ku mitundu ina ya insulin kupita ku mankhwalawa kutha kuchitika kokha moyang'aniridwa ndi achipatala. Makamaka kuyang'anira mkhalidwe wa kagayidwe kazachilengedwe ndikofunikira mu masabata oyambilira pambuyo pa kusintha kumeneku.
Insuman Rapid GT nthawi zambiri imaperekedwa kwa mphindi 15-20 asanadye chakudya. Mgwirizano wamankhwala mankhwala amaloledwa. Tsamba la jakisoni liyenera kusinthidwa nthawi iliyonse. Kusintha kwa jekeseni (mwachitsanzo, kuyambira pamimba mpaka ntchafu) kuyenera kuchitika pokhapokha mukaonana ndi dokotala.
Insuman Rapid GT imatha kutumikiridwa kudzera mu mankhwalawa a hyperglycemic coma ndi ketoacidosis, komanso kukwaniritsa kufotokozera kwa kagayidwe kachakudya ka pre-, intra- komanso postoperative nyengo kwa odwala omwe ali ndi matenda osokoneza bongo.
Insuman Rapid GT sigwiritsidwe ntchito mitundu yosiyanasiyana ya mapampu a insulini (kuphatikizira omwe amaikidwira), momwe amaumbira silicone.
Osasakaniza Insuman Rapid GT ndi insulin ya ndende ina (mwachitsanzo, 40 IU / ml ndi 100 IU / ml), ndi insulini yoyambira nyama kapena mankhwala ena. Gwiritsani ntchito mayankho omveka okha, opanda khungu la Insuman Rapid GT popanda zozizwitsa zilizonse.
Kumbukirani kuti kuchuluka kwa insulini mu vial ndi 100 IU / ml, kotero muyenera kugwiritsa ntchito syringes zapulasitiki zopangidwira insulin. Syringe siyenera kukhala ndi mankhwala ena aliwonse kapena zotsalira zake.
Pamaso gawo loyambirira la insulin kuchokera pambale, chotsani pulasitiki (kukhalapo kwa kapuyo ndi umboni wa vial wosatsutsana). Njira yothetsera jakisoni iyenera kukhala yowonekera komanso yopanda utoto.
Asanatenge insulini kuchokera ku vial, mpweya wofanana ndi mankhwala omwe amaperekedwa ndi insulin umayamwa mu syringe ndikujowina mu vial (osalowa madzi). Kenako vala yokhala ndi syringe imasinthidwa mozungulira ndi syringe ndipo kuchuluka kwa insulini kumatengedwa. Pamaso jakisoni, chotsani thovu lakumanzere mu syringe.
Khungu limatengedwa pamalo a jakisoni, singano imayikidwa pansi pakhungu, ndipo insulin imayamwa pang'onopang'ono. Pambuyo pa jekeseni, singano imachotsedwa pang'onopang'ono ndipo tsamba lamalowo limakanikizidwa ndi swab ya thonje kwa masekondi angapo. Tsiku lokhala ndi insulin kit kuchokera pa vial iyenera kulembedwa pa cholembera cha vial.
Mutatsegula mabotolo amatha kusungidwa pa kutentha osaposa + 25 ° C kwa masabata anayi pamalo otetezedwa ku kuwala ndi kutentha.

Kuchita ndi mankhwala ena

Kugwiritsa ntchito munthawi yomweyo mankhwala ambiri kumatha kufooketsa kapena kuwonjezera mphamvu yochepetsera shuga ya Insuman Rapida GT. Chifukwa chake, mukamagwiritsa ntchito insulin, simungatenge mankhwala ena popanda chilolezo chapadera cha dokotala.
Hypoglycemia imatha kuchitika ngati odwala nthawi yomweyo omwe ali ndi insulin amalandila ACE inhibitors, acetylsalicylic acid ndi ma salicylates ena, amphetamine, anabolic steroids ndi mahomoni ogonana amuna, cybenzoline, fibrate, disopyramide, cyclophosphamide, phenoxyfin amine, glucose, glucose, glucose , pentoxifylline, phenoxybenzamine, phentolamine, propoxyphene, somatostatin ndi mayendedwe ake, sulfonamides, tetracyclines, tritocqualin kapena trophosphamide.
Kuchepetsa mphamvu ya insulin kumatha kuwonedwa limodzi ndi insulin ndi corticotropin, corticosteroids, diazoxide, heparin, isoniazid, barbiturates, nicotinic acid, phenolphthalein, phenothiazine, phenytoin, diuretics, danazrogen, estrogen, estrogen. zotulutsa.
Odwala omwe amalandila insulin ndi clonidine, reserpine kapena mchere wa lithiamu, zonse zimafooketsa komanso zomwe zimapangitsa kuti ntchito ya insulin iwoneke. Pentamidine imatha kuyambitsa hypoglycemia kenako hyperglycemia.
Kumwa mowa kumatha kuyambitsa hypoglycemia kapena kuchepetsa shuga wochepa wokhala m'magazi kuti akhale woopsa. Kulekerera kwa mowa kwa odwala omwe amalandira insulin kumachepetsedwa. Mitundu yovomerezeka ya zakumwa ziyenera kutsimikiziridwa ndi dokotala. Uchidakwa wambiri, komanso kugwiritsa ntchito mankhwala osokoneza bongo mopitirira muyeso, umatha kukhudza glycemia.
Ma Beta-blockers amawonjezera chiopsezo cha hypoglycemia ndipo, pamodzi ndi othandizira ena achifundo (clonidine, guanethidine, reserpine) amatha kufooketsa kapena ngakhale kufinya chiwonetsero cha hypoglycemia.

Hypoglycemia, zotsatira zoyipa kwambiri, zimatha kukhala ngati mlingo wa insulin woperekedwa umaposa kufunikira kwake (onani "Njira zopewera komanso malangizo apadera").
Kusintha kwakukulu mu shuga m'magazi kumatha kubweretsa zosokoneza pang'ono. Komanso, makamaka ndi insulin Therapy, kuwonjezereka kwakanthawi kwa matenda ashuga retinopathy ndikotheka. Odwala omwe ali ndi proliferative retinopathy, osagwiritsa ntchito njira ya laser, zovuta kwambiri zam'magazi zingayambitse khungu.
Nthawi zina atrophy kapena hypertrophy ya adipose minofu imatha kuchitika malo a jekeseni, omwe amatha kupewedwa ndikusintha malo a jekeseni nthawi zonse. Nthawi zina, kufupikiratu kumatha kuchitika pamalowo jekeseni, ndikusowa ndikupitiliza mankhwala. Ngati erythema yofunika ikakhazikitsidwa, limodzi ndi kuyabwa ndi kutupa, ndikufalikira mwachangu mpaka pamalo a jakisoni, komanso zotsatira zina zovuta pazigawo za mankhwala (insulin, m-cresol), ndikofunikira kudziwitsa dokotala mwachangu, monga nthawi zina Kuchita kotereku kukhoza kuwononga moyo wa wodwalayo. Kusintha kwakukulu kwa Hypersensitivity kumachitika kawirikawiri. Amathanso kuphatikizidwa ndi chitukuko cha angioedema, bronchospasm, kugwa kwa magazi komanso kusowa kwa anaphylactic. Hypersensitivity reaction imafunikira kukonza mwachangu pakanthawi kovomerezeka ndi insulin komanso kukhazikitsidwa kwa njira zoyenera zadzidzidzi.
Mwina kupangika kwa ma antibodies ku insulin, komwe kungafune kusintha kwa mlingo wa insulin. Ndiwothekanso kusungidwa kwa sodium komwe kumayamba chifukwa cha kutupa kwa minofu, makamaka mukamaliza kumwa mankhwalawa.
Ndi kuchepa kwambiri kwa shuga m'magazi, ndizotheka kukhala ndi hypokalemia (zovuta kuchokera ku mtima) kapena kukula kwa edema ya ubongo.
Popeza zovuta zina zimatha kukhala zowopsa pamoyo, ndikofunikira kudziwitsa adokotala zikafika.
Ngati mukuwona mavuto aliwonse, chonde onani dokotala!

Mankhwala osokoneza bongo kwambiri amatha kuyambitsa matenda oopsa ndipo nthawi zina amatha kukhala oopsa kwa hypoglycemia. Ngati wodwalayo akudziwa, ayenera kumwa shuga kenako ndikumatenga zinthu zomwe zili ndi chakudya (onani "Malangizo ndi malangizo apadera"). Ngati wodwala ali osazindikira, 1 mg ya glucagon / m iyenera kuperekedwa. Ngati njira ina, kapena ngati jakisoni wa glucagon sagwira ntchito, 20-30 ml ya 30% -50% iv solution ya glucose imaperekedwa. Ngati ndi kotheka, kuyambiranso kwa shuga pamwambapa ndi kotheka. Mwa ana, kuchuluka kwa shuga komwe kumayendetsedwa kumayikidwa molingana ndi kulemera kwa thupi la mwana.
Milandu ya hypoglycemia yoopsa kwambiri kapena yayitali yotsata shuga, tikulimbikitsidwa kupaka njira yochepetsera shuga pofuna kupewa kukonzanso kwa hypoglycemia. Mu ana aang'ono, ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magazi, molingana ndi chitukuko chachikulu cha hyperglycemia.
Pazinthu zina, ndikulimbikitsidwa kuti odwala azigonekedwa m'chipinda cha odwala osamala kwambiri kuti athe kuwunika moyenera komanso kuwunika.

Injection solution 100 IU / ml mu 5 ml Mbale ..
Mu phukusi la mabotolo 5 limodzi ndi malangizo ogwiritsira ntchito.

Sungani kutentha kwa + 2 ° C mpaka + 8 ° C (gawo lama masamba a firiji yanyumba). Pewani kuzizira, popewa kulumikizana mwachindunji ndi botolo ndi makoma a chipinda chaulere kapena chosungira pozizira.
Pewani patali ndi ana!

Moyo wa alumali ndi zaka 2.
Mankhwalawa sangathe kugwiritsidwa ntchito atatha tsiku lotha kusonyezedwa phukusi.

Tchuthi kuchokera ku malo ogulitsa mankhwala : mankhwala

Yopangidwa ndi Aventis Pharma Deutschland GmbH, Germany .
Bruningstrasse 50, D-65926, Frankfurt, Germany.

Zodandaula za ogula ziyenera kutumizidwa ku adilesi ya ofesi yoimira Russia :
101000, Moscow, Ulansky Lane, 5

Kutengera ndi chithunzi cha chipatala, wodwalayo amatenga mankhwala osiyanasiyana.

Pazinthu zomwe zimafuna chithandizo cha insulin, jakisoni wa hypoglycemic ndi mankhwala. Imodzi mwa mankhwalawa ndi Insuman Rapid GT.

Makhalidwe wamba

Insuman Rapid ndi mankhwala opangira matenda a shuga. Amapezeka mu mawonekedwe amadzimadzi ndikugwiritsa ntchito jakisoni.

Muzochita zamankhwala, imagwiritsidwa ntchito ndi mitundu inanso ya insulin. Amasankhidwa kuti akhale ndi matenda ashuga amtundu 1 komanso mtundu wa matenda ashuga wa 2 osagwira mapiritsi ochepetsa shuga, tsankho lawo kapena zotsutsana.

Homoni amakhala ndi vuto la hypoglycemic. Kuphatikizika kwa mankhwalawa ndi insulin yaumunthu ndi 100% solubility yochepa. Thupi limapezeka mu labotale ndi genetic engineering.

Sungunuka insulini - yogwira mankhwala. Zotsatirazi zidagwiritsidwa ntchito ngati chowonjezera: m-cresol, glycerol, madzi oyeretsedwa, hydrochloric acid, sodium hydroxide, sodium dihydrogen phosphate dihydrate.

Mankhwala

Insuman amachepetsa shuga. Zimatengera mankhwala okhala ndi nthawi yofulumira komanso yochepa.

Zotsatira zake zikuyembekezeka theka la ola jakisoni atatha mpaka maola 7. Kuzindikira kwakukulu kumawonedwa pa ora la 2 pambuyo pothandizidwa ndi subcutaneous.

Chomwe chimagwira chimagwira ma cell receptor kuti apange insulin receptor zovuta. Zimatsutsa kaphatikizidwe wama michere ofunikira ndikuti timalimbikitse njira zamagetsi. Zotsatira zake, kuyamwa ndi kuyamwa kwa glucose ndi thupi kumakulitsidwa.

• kumapangitsa kaphatikizidwe wa mapuloteni,
• zimalepheretsa kuwonongeka kwa zinthu
• timaletsa glycolenolysis ndi glyconeogeneis,
• timapititsa patsogolo mayendedwe ndi mayamwidwe a potaziyamu,
• Amasintha kaphatikizidwe wamafuta achilengedwe m'chiwindi ndi zimakhala,
• Imachepetsa kuwonongeka kwa mafuta,
• bwino zoyendera ndi mayamwidwe amino acid.

Kusintha kwa Mlingo

Mlingo wa mankhwalawa ungasinthidwe milandu:

• ngati moyo ukusintha
• kuchuluka kwa chidwi ndi ntchito yogwira,
• kusintha kwa odwala
• mukamasintha kuchokera ku mankhwala ena.

Nthawi yoyamba mutasintha chinthu china (mkati mwa masabata awiri), kuyendetsa bwino shuga kumalimbikitsidwa.

Kuchokera pamitengo yapamwamba yamankhwala ena, ndikofunikira kusinthana ndi mankhwalawa moyang'aniridwa ndi achipatala.

Mukasintha kuchokera ku nyama kupita ku insulin yaumunthu, kusintha kwamankhwala kumachitika.

Kuchepetsa kwake kumafunikira pagulu lotsatira la anthu:

• shuga woyika kale pamankhwala,
• kumwa mankhwala mosamala kwambiri,
• makonzedwe a kupangika kwa dziko la hypoglycemic.

Zotsatira zoyipa ndi bongo

Izi zotsatirazi zoyipa zimasiyanitsidwa ndi makonzedwe:

Pakakhala mankhwala osokoneza bongo, wodwalayo amatha kutsitsa shuga mpaka otsika. Ndi mawonekedwe ofatsa, 15 g shuga ayenera kumwedwa.

Fomu yayikulu ya kukomoka, kutuluka kwa chikumbumtima kumafuna kuyambitsidwa kwa glucagon (intramuscularly). Mwinanso kuyambitsa kwa dextrose (kudzera m'mitsempha).

Pambuyo kukhazikika kwa mkhalidwe wa wodwalayo, ndikofunikira kumwa mankhwala osungirako okwanira. Kwa nthawi yayitali atachotsa zizindikiro za hypoglycemia, kuwunikira zomwe zofunikira pakufunika, popeza kuwonetseredwa kwachiwiri ndikotheka. Mwapadera, wodwalayo amagonekedwa m'chipatala kuti apenye.

Kuchita ndi mankhwala ena

Popanda upangiri wa dokotala, kugwiritsa ntchito mitundu inanso ya mankhwala osavomerezeka sikulimbikitsidwa. Amatha kuchulukitsa kapena kuchepetsa mphamvu ya insulin kapena kupangitsa kuti pakhale zovuta.

Kutsika kwa mphamvu ya mahomoni kumawonedwa ndikugwiritsira ntchito njira zakulera, ma glucocorticosteroids mahomoni (progesterone, estrogen), diuretics, mankhwala angapo a antipsychotic, adrenaline, mahomoni a chithokomiro, glucagon, barbiturates.

Kukula kwa hypoglycemia kumatha kuchitika limodzi ndi mankhwala ena othandizira odwala matenda ashuga. Izi zikugwira ntchito pa maantibayotiki a sulfonamide, Mao inhibitors, acetylsalicylic acid, fibrate, testosterone.

Mowa ndi mahomoni amachepetsa shuga mpaka pamavuto, amachititsa hypoglycemia. Mlingo wovomerezeka ndi dokotala. Muyeneranso kusamala pakumwa mankhwala oletsa - - kudya kwawo mopitirira muyeso kumakhudza kwambiri shuga.

Pentamidine imatha kuyambitsa zochitika zosiyanasiyana - hyperglycemia ndi hypoglycemia. Mankhwala amatha kupweteketsa mtima. Makamaka mwa anthu omwe ali pachiwopsezo.

Zindikirani! Alumali moyo wa yankho mu syringe cholembera si zoposa mwezi. Tsiku la kudya koyamba kwa mankhwala liyenera kudziwika.

Mankhwala ozindikiritsa (ofananitsa fomu yotulutsira komanso kupezeka kwa gawo lomwe limagwira ntchito) akuphatikiza: Actrapid Hm, Vosulin-R, Insuvit N, Rinsulin-R, Humodar, Farmasulin N. Mankhwalawa amaphatikizapo insulin ya anthu.

Chikhumbo cha munthu chokhala ndi moyo wathanzi, kuletsa kugwiritsa ntchito zinthu zovulaza, kuchita masewera olimbitsa thupi komanso kusapezeka kwa zizolowezi zoyipa ndizofunikira kwambiri kuti pakhale thanzi laumunthu nthawi zambiri. Komabe, nthawi zina, mosiyana ndi malingaliro aliwonse, munthu amene amagwiritsa ntchito bwino thanzi lake mosamala, amakumana ndi vuto lalikulu la metabolic. Kodi zingachitike bwanji ngati munthu sanamwe, sanamwe mowa mopitirira muyeso, kupewa nkhawa ndikuchita masewera olimbitsa thupi? Cholinga chake, mwatsoka, chagona mu chibadwa chamtsogolo, chomwe ndicho chofunikira kudziwa pamenepa, umboni womwe ungakhale matenda a matenda a shuga 1. Kodi chodabwitsa cha matenda awa ndi chiyani ndipo ndi makina ake amakula?

Kodi matenda ashuga ndi chiani?

Mtundu woyamba wa matenda a shuga ndi matenda omwe amayamba chifukwa cha kufa kwa maselo ena omwe amapanga insulini ya mahomoni mu kapamba. Kutha kwa maselo ndi kuchepa kwa insulini kumayambitsa vuto lalikulu la metabolic njira ndi hyperglycemia.

Pankhaniyi, wodwalayo akhoza kumva zotsatirazi:

Matendawa, osapezeka pa nthawi yake, amatha kutsogolera impso, mtima, kudula miyendo ngakhale kufa. Ichi ndichifukwa chake ndikofunikira kwambiri kuti munthu agwiritse matendawa ndikangofunika kuti ayambe kulandira chithandizo munthawi yake.

Kodi ndichifukwa chiyani insulin ndi yofunika kwambiri kwa thupi?

Popeza matenda amtunduwu amawonekera motsutsana ndi kusowa kwa insulin, ndiye kuti chithandizo chamankhwala chiyeneranso kugwirizananso ndi kubwezeretsanso kuchepa kwa timadzi ta m'thupi totere. Komabe, poyambira ndikofunikira kumvetsetsa kuti ntchito yake ndi yotani?

Ntchito zomwe amathetsa ndi izi:

• Kuwongolera kuwonongeka kwa glucose, komwe ndi gwero lalikulu la zakudya zamafupa am'mimba ndi ma neurons aubongo.
• Phatikizani kulowerera kwa glucose kudzera m'makoma a minofu ya minofu.
• Kusintha kukula kwa mapangidwe a mafuta ndi mapuloteni, kutengera zosowa za thupi.

Popeza insulini ndiye hormone yokhayo yomwe imagwira ntchito zosiyanasiyana komanso zosiyanasiyana, ndiyofunikira kwambiri m'thupi la munthu. Ichi ndichifukwa chake ndi matenda ashuga, wodwalayo amakakamizidwa kutenga chinthu chomwe mawonekedwe ake ali pafupi ndi timadzi timeneti. Mankhwalawa amapulumutsa wodwalayo pakukula kwa ziwalo zamkati ndi mitsempha yamagazi.

Mitundu ya insulin

Kusiyana kwakukulu pakati pa kufananizira kwa insulin ya anthu masiku ano ndi zifukwa izi:

• Zomwe mankhwalawa amapangidwa.
• Kutalika kwa mankhwalawa.
• Mlingo wa kuyeretsedwa kwa mankhwalawa.

Mwa kapangidwe kake, kukonzekera kumatha kugawidwa ngati ndalama zomwe zimaperekedwa kuchokera ku ng'ombe, zomwe nthawi zambiri zimayambitsa mavuto ndi chifuwa, kuchokera ku nkhumba ndikupezeka ndi genetic engineering. Mankhwalawa amaphatikizapo, mwachitsanzo, Germany Insulin Rapid GT.

Malinga ndi nthawi yowonekera, mankhwalawa amagawidwa m'mitundu yotere:

• Insulin yochepa, yomwe imaperekedwa kotala la ola limodzi asanadye, kuti ifanane ndi kukula kwa mahomoni mwa munthu wathanzi atatha kudya. Ndalamazi ndi monga Insulin Insuman Rapid.
• Yaitali, yomwe imayenera kutumikiridwa kamodzi kapena kawiri pa tsiku, kuti athe kutsata kupangika kwa mahomoni.

Nthawi zambiri, mitundu yonse iwiri ya mahomoni imaperekedwa kwa wodwala kuti akwaniritse zofunikira za thupi tsiku ndi tsiku. Komabe, kwa anthu omwe sangathe kuwongolera mkhalidwe wawo chifukwa cha ukalamba kapena matenda amisala, muyezo woyeserera wa mankhwala umaperekedwa. Wodalirika komanso wowonetsetsa kusintha kwa mkhalidwe wake, munthu amatha kuwerengera payekha mlingo wa Short Insulin Rapid.

Zomwe amamwa mankhwalawo

Kumwa mankhwala osokoneza bongo kumathandizira wodwala kuti azitha kukonza yekha zakudya, osadalira kwambiri zakudya komanso zochita za tsiku ndi tsiku. Kuti muchite izi, ndikofunikira kuwerengera moyenera kuchuluka kwa chakudya komanso kuchuluka kwa shuga m'magazi musanadye.

Kulandila kwa Insulin Insuman Rapid GT kumatha kusintha kwambiri moyo wa wodwalayo, chifukwa zimapangitsa kuti muzitha kuganizira za mtundu wa moyo wa munthu, chakudya chake.

Njira yogwiritsira ntchito mankhwalawa ndi muyezo, komanso mawonekedwe a kuvomereza ndi contraindication, ayenera kuphunziridwa mosamala malinga ndi malangizo a Insulin Rapid, komanso kukambirana ndi dokotala. Chofunikanso kwambiri ndikuti wodwalayo athe kuwerengetsa moyenera mankhwalawo.

Njira ya makonzedwe

Malangizo ogwiritsira ntchito Insuman Bazal GT imapereka kusankha kwa munthu payekha, potengera momwe wodwalayo alili komanso kufunika kwake kwa mahomoni. Mlingo amawerengedwa ndi kuchuluka kwa shuga m'magazi, zolimbitsa thupi, mkhalidwe wa kagayidwe kazakudya.

Pafupifupi, 0,5-1.0 Insuman Bazal GT imafunikira patsiku pafupifupi 1 kg ya kulemera kwamthupi la wodwala. Amaphatikizidwanso ndi insulin yokhala ndi nthawi yayitali, makamaka kuchokera kwa wopanga yekha. Kusintha kwa magazi kumachitika potsatira milandu iyi:

• Kusintha kuchokera ku insulin ya nyama.
• Kusintha kwa mankhwala opanga majini amtundu wa anthu.
• Kusintha kwa sungunuka waanthu insulin ndi yotalikirapo.
• Kuchulukitsa kapena kuchepa kwa odwala komanso kuchita masewera olimbitsa thupi.
• Zomwe zimapangidwira kukula kwa hyper- kapena hypoglycemia.

Mlingo wa okalamba umasinthidwa. Kwa okalamba, kufunika kwa insulini kumakhala kotsika, motero, mankhwalawa amasankhidwa ndikuwusintha mosamala kwambiri kuti asayambitse vuto la hypoglycemia. Odwala omwe ali ndi matenda a chiwindi ndi impso omwe adutsa gawo la kusakwanira kwa ntchito, kuchepetsa mlingo kumafunika.

Bazal GT phukusi lomwe lili ndi Mbale 5 za mankhwala mu 5 ml.Ikupezekanso m'mak cartridge atatu. Kuti jekeseni, mphindi 45-60 musanadye, kuchuluka kwa kuyimitsidwa kumasonkhanitsidwa mu syringe ya insulin. Lowani mosaneneka mu khola pamimba, m'chiuno. Tsamba la jakisoni limasinthidwa nthawi ndi nthawi ndikusinthidwa pakulimbikitsidwa ndi dokotala. Kuchuluka kwa kumizidwa m'magazi ndikukula kwa zotsatira zake zimatengera izi. Izi zaletsedwa kuchita izi:

• Muuzeni mankhwalawo.
• Gwiritsani ntchito pampu ya insulin.
• Sakanizani jakisoni m'modzi ndi mitundu ina ya kukonzekera kwa insulin, kuphatikiza chiyambi cha nyama, komanso ndende ina.

Musanadzaze yankho mu syringe, muyenera kutembenuzira botolo ndikuwugwedeza kuti apange kuyimitsidwa. Siyenera kukhala yopanda thovu ndikukhala ndi utoto wosiyana ndi omwe akuwonetsedwa mu malangizo. Ngati mutagwedezeka ndi ma glake ndi zipupa mutapangidwa pagalasi, ndiye kuti mankhwalawa sangathe kugwiritsidwa ntchito.

Mukatha kugwiritsa ntchito koyamba, botolo limatha kusungidwa kwa milungu inayi pamtunda wosaposa 25 digiri, lotetezedwa pakuwala. Pofuna kuti musaiwale, tsiku lotsegulira likuwonetsedwa. Sikulimbikitsidwa kuyika mabotolo otseguka mufiriji: kubayidwa ndi jakisoni wozizira kumapangitsa kupweteka kwambiri.

Analogi ndi mtengo

Mtengo wa Insuman Bazal, kutengera kuchuluka kwa mabotolo, umachokera ku 268 mpaka 1695 rubles. Mtengo umasiyana m'magawo osiyanasiyana a Russia ndi ma pharmacista opezeka pa intaneti.

Rinsulin NPH (mtengo kuchokera ku ma ruble 420), Biosulin (kuchokera ku ma ruble 500), Protamine Insulin ChS (310 ma ruble), Rosinsulin (kuchokera ku ruble 1000) atha kukhala fanizo la Insuman Bazal.

M'malo moyenerera mankhwalawa amatha kusankha dokotala woyenera yekha. Chifukwa chake, pankhani ya insulin yothandizira matenda a shuga, kudzichiritsa nokha kuli kowopsa.

Mlingo

Kuyimitsidwa kwa subcutaneous makonzedwe a 100 IU / ml

1 ml ya kuyimitsidwa kuli

chogwira ntchito ndi insulin (HR 1799) yofanana ndi 100 IU ya insulin 100 IU (3.571 mg),

excipients: glycerol 85%, protamine sulfate, metacresol, phenol, zinc chloride, sodium dihydrogen phosphate dihydrate, sodium hydroxide, ana hydrochloric acid, madzi a jekeseni.

Kuthamangitsa mwachangu kuyimitsidwa kwa zoyera kapena pafupifupi zoyera. Wopatsa chidwi ndi njira yowonekera kapena yotsimikizirika.

Zotsatira zoyipa Insuman Rapid GT

Kuchokera pamtima: pafupipafupi osadziwika - kuchepa kwa magazi.

Kuchokera kumbali ya kagayidwe ndi zakudya: nthawi zambiri - kutupa, kusadziwika pafupipafupi - kusungidwa kwa sodium. Zotsatira zomwezi zimatheka ndikusintha kwa kusakwanira kwa kagayidwe kachakudya chifukwa chogwiritsa ntchito kwambiri insulin.

Kuchokera kumbali ya gawo la masomphenyawo: kusunthika sikudziwika - kusokonezeka kowoneka kwakanthawi (chifukwa chakusintha kwakanthawi kwa ma mandala amaso ndi ma index awo othandizanso), kuwonongeka kwakanthawi machitidwe a matenda ashuga (chifukwa cha insulin yayikulu pakukonzanso kwakukulu pakulamulira kwamatenda a glycemic), makamaka osakhalitsa alandire chithandizo cha Photocoagulation (laser mankhwala).

Pa khungu ndi subcutaneous minofu: pafupipafupi sizikudziwika - kukula kwa lipodystrophy pamalo opangira jakisoni ndikuchepetsa kwa insulin. Kusintha komwe kumayambira jakisoni mkati mwa malo oyendetsera kungathandize kuchepetsa kapena kusiya izi.

Zovuta ndi zovuta zina pamalo opangira jakisoni: pafupipafupi sizikudziwika - redness, ululu, kuyabwa, urticaria, kutupa kapena kutupa pakhungu. Zinthu zomwe zimatchulidwa kwambiri ndi insulini pamalo opangira jakisoni nthawi zambiri zimatha patatha masiku angapo kapena milungu ingapo.

Zizindikiro mwachitsanzo, insulin yochulukirapo, mwachitsanzo, kuyambitsa insulin yochulukirapo poyerekeza ndi chakudya kapena mphamvu, imatha kubweretsa hypoglycemia yayitali komanso nthawi yayitali.

Chithandizo: Zolemba zofatsa za hypoglycemia (wodwalayo amadziwa) zitha kuyimitsidwa ndikutenga chakudya mkati. Kusintha kwa mlingo wa insulin, kudya, komanso zolimbitsa thupi kungafunike. Ziwonetsero zoopsa za hypoglycemia ndi chikomokere, kukomoka kapena kuwonongeka kwa mitsempha zitha kuyimitsidwa ndi / m kapena s / c makonzedwe a glucagon kapena i / v ndi yankho la dextrose. Mu ana, kuchuluka kwa dextrose kutumikiridwa kumayikidwa molingana ndi kulemera kwa thupi la mwana. Pambuyo pakuwonjezera kuchuluka kwa shuga m'magazi, kudya zakudya zopatsa mphamvu komanso kuunika kungafunike, popeza Pambuyo pakuwonekera kachipatala pakutha kwa zizindikiro za hypoglycemia, kuyambiranso kwake ndikotheka. Milandu ya hypoglycemia yoopsa kapena yotalika potsatira jekeseni wa glucagon kapena dextrose, tikulimbikitsidwa kuti njira yotsika kwambiri ya dextrose imayikiridwa kuti tipewe kukonzanso kwa hypoglycemia. Mu ana aang'ono, ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magazi, molingana ndi chitukuko chachikulu cha hyperglycemia. Pazinthu zina, ndikulimbikitsidwa kuti wodwala azigonekedwa m'chipinda cha odwala osamala kwambiri kuti athe kuyang'anitsitsa momwe alili komanso kuwunika komwe akupitiliza kuchipatala.

Kugwiritsa ntchito mosiyanasiyana ndi mankhwala am'mlomo a hypoglycemic, ACE inhibitors, disopyramide, fibrate, fluoxetine, Mao inhibitors, pentoxifylline, propoxyphene, salicylates, amphetamine, anabolic steroids ndi mahomoni ogonana amuna, cybenzoline, phenophosphamine, phenophosphamine ndi phenophosphamine ake analogues, sulfonamides, tetracyclines, tritokvalin kapena trophosphamide amatha kupititsa patsogolo hypoglycemic zotsatira za insulin komanso draspolozhennost hypoglycemia.

The ntchito munthawi yomweyo corticotropin, corticosteroids, danazol, diazoxide, okodzetsa, glucagon, isoniazid, oestrogens ndi gestagens (mwachitsanzo, kupezeka PDA), phenothiazine ofanana nawo, kukula timadzi, mankhwala sympathomimetic (mwachitsanzo, wa epinephrine, salbutamol, terbutaline), mahomoni a chithokomiro, barbiturates, nicotinic acid, phenolphthalein, mankhwala a phenytoin, doxazosin imatha kufooketsa mphamvu ya insulin.

Beta-blockers, clonidine, mchere wa lithiamu ukhoza kukhala wowonjezera kapena kufooketsa mphamvu ya hypoglycemic ya insulin.

Ethanol imatha kupanga kapena kufooketsa mphamvu ya hypoglycemic ya insulin. Kudya kwa Ethanol kumatha kuyambitsa hypoglycemia kapena kuchepetsa shuga wambiri m'magazi kuti akhale owopsa. Kulekerera kwa Ethanol mwa odwala omwe amalandira insulin kumachepetsedwa. Dokotala ayenera kudziwa kuchuluka kovomerezeka kwa Mowa.

Pogwiritsa ntchito munthawi yomweyo ndi pentamidine, kukula kwa hypoglycemia ndikotheka, komwe nthawi zina kumatha kukhala hyperglycemia.

Pogwiritsa ntchito munthawi yomweyo ndi othandizira achifundo, monga beta-blockers, clonidine, guanethidine ndi reserpine, kufooka kapena kusapezeka kwathunthu kwa zizindikiro za Reflex (poyankha hypoglycemia) kuyambitsa kwamachitidwe amanjenje amanjenje ndikotheka.

Mankhwalawa amayenera kusungidwa pamalo amdima, osatheka ndi ana pa kutentha kwa 2 ° C mpaka 8 ° C. Moyo wa alumali: zaka ziwiri.

Mankhwala Opezeka

Insulin "Insuman Rapid GT" ithandizanso kupereka msanga-kuchepetsa msanga zinthu zomwe zimachitika mphindi iliyonse. Kupatula apo, matenda ashuga ndi matenda oopsa omwe nthawi zambiri amachititsa kufa kapena kulumala. Kuti mupeze yankho la panthawi yake, othandizira osasinthika ndi jakisoni wa insulin yofulumira.

Kutulutsa mafomu ndi kapangidwe kake

Njira yothetsera vutoli imapezeka m'mbale kapena ma cartridge. Kuyika ndi jekeseni ya solostar yotayikira ikuchitika.

Chithandizo chophatikizika m'madzi ndi insulin yaumunthu. Kuzungulira kwa yankho ndi 3.571 mg, kapena 100 IU / 1 ml.

Zotsatira za pharmacological

Mphamvu ya pharmacological ikuwonetsedwa ndi kuchepa kwa glucose. Pali kuchepa kwa njira zowonongeka, kuthamanga kwa zotsatira za anabolic. Mankhwala amalimbikitsa kusamutsa glucose mu malo amkati mwazinthu, kuphatikiza kwa zovuta glycogen chakudya mu minofu minofu ndi chiwindi. Kutulutsa kwa pyruvic acid kuchokera mthupi kumakhala bwino. Potengera maziko awa, kupanga glucose kuchokera ku glycogen, komanso kuchokera ku mamolekyulu a mankhwala ena okhala ndi michere, amachepetsa.

Makina ochitapo kanthu amadziwika ndi kuwonjezeka kwa kagayidwe ka glucose mpaka mafuta acids komanso kuchepa kwa kuchuluka kwa lipolysis.

Kugawidwa kwa amino acid ndi potaziyamu m'maselo, metabolism ya protein imayenda bwino.

Momwe mungatengere Insuman Rapid GT

Njira yothetsera vutoli ndi yothandiza kuti mtsempha wake alowetse magazi mkati. Palibe yunifolomu yovomerezeka yamankhwala. Njira zochizira zimafunikira kusintha kwa dokotala. Odwala osiyanasiyana ali ndi magawo osiyanasiyana a glucose omwe amafunikira kuti azisamalira, motero, kuchuluka kwa mankhwalawo ndi njira zochizira zowerengedwa zimawerengedwa payekhapayekha. Dokotala wopezekapo amaganizira zochita za wodwalayo.

Kufunika kusintha kuchuluka kwa mankhwalawa kumatha kuchitika:

1. Mukamasintha mankhwalawo ndi mtundu wina wa insulin.
2. Ndi kukhudzika kowonjezereka kwa chinthucho chifukwa cha kuwongolera kwa kagayidwe kazinthu.
3. Mukataya kapena kulemera ndi wodwala.
4. Mukamakonza zakudya, kusintha kuchuluka kwa katundu.

Makina oyendetsera zinthu ndi ozama. Ndi bwino kuchita njirayi kwa mphindi 15 kapena 20 musanadye. Ndikofunikira kusintha malo a jakisoni ndi jakisoni aliyense. Komabe, kutengera gawo la kayendetsedwe ka yankho, ma pharmacokinetics a mankhwalawa amatha kusintha, kotero kusintha kwa malo oyang'anira kuyenera kuvomerezedwa ndi adokotala.

Ndikofunika kulabadira kupezeka kwa chipewa. Izi zikuwonetsa kukhulupirika kwa nkhanizo. Palibe zidutswa zomwe zimayenera kukhalapo mu yankho, madziwo ayenera kukhala owonekera.

Zotsatirazi ziyenera kulingaliridwa:

1. Mukamagwiritsa ntchito njirayi mosamala, gwiritsani ntchito syringe yoyenera yapulasitiki.
2. Choyamba, mpweya umasonkhanitsidwa mu syringe, kuchuluka kwake kuli kofanana ndi mlingo wa yankho. Lowetsani malo opanda kanthu m'botolo. Kuchita kutembenuka. Yothetsera ikuchitika. Pasapezeke thovu lililonse mu syringe. Pang'onopang'ono Lowani yankho mu khola la khungu lopangidwa ndi zala.
3. Pa zilembo muyenera kufotokoza tsiku lomwe mankhwala oyamba adachitika.
4. Mukamagwiritsa ntchito makatoniji, kugwiritsa ntchito ma jakisoni (zolembera) pamafunika.
5. Katoniyo amalimbikitsidwa kuti asiyidwe firiji kwa 1 kapena 2 maola, monga kuyambitsidwa kwazinthu zopweteka kumakhala kowawa. Pamaso jakisoni, chotsani mpweya wotsalira.
6. Katiriji sikulembedwanso.
7. Ndi cholembera chosagwira ntchito, syringe yoyenera imaloledwa.

Kukhalapo kwa zotsalira za mankhwala ena mu syringe ndikosavomerezeka.

Pa mbali ya ziwalo zamasomphenya

Kusinthasintha komwe kumanenedwa pakuwongolera glycemic kungayambitse kusokonezeka kwakanthawi kwa khungu la mandala amaso, kusintha kwa mlozera. Kusintha kwakuthwa kwa zizindikiro chifukwa cha kuchuluka kwa mankhwala kungakhale limodzi ndi kuwonongeka kwakanthawi mkhalidwe wa retinopathy.

Mu kwambiri hypoglycemia yokhala ndi retinopathy yowonjezereka, kuwonongeka kwa retina kapena kuwala kwa minyewa yochepa kwakanthawi kumatha.

Kuphatikiza kophatikizidwa

Kuphatikiza kwa mankhwalawa ndi insulin ya nyama ndi analogues sikuyikidwa pambali.

Kuphatikiza kwa Pentamidine kumapangitsa kuti pakhale zovuta.

Zinthu zotsatirazi ndi kukonzekera kumafooketsa mphamvu yotsitsa shuga:

• corticosteroids
• adrenocorticotropic timadzi,
• zotumphukira za phenothiazine ndi phenytoin,
• glucagon,
• mahomoni ogonana achikazi,
• kukula kwamafuta,
• nicotinic acid
• phenolphthalein,
• okodzetsa
• mankhwala osokoneza bongo
• kupanga androgen Danazole,
• anti-TB mankhwala a Isoniazid,
• adrenoblocker Doxazosin.

Sympathomimetics ndi iodinated tyrosine zotumphukira zimafooketsa mayankho a yankho.

Kuphatikiza komwe kumafunikira kusamala

Mankhwala otsatirawa amalimbikitsa chiopsezo cha zovuta:

• endrogens ndi anabolics,
• Mankhwala angapo ochizira matenda amtima komanso a mtima.
• CNS zolimbikitsa,
• antiarrhythmic mankhwala cybenzoline,
• propoxyphene analgesic,
• Pentoxifylline angioprotector,
• cytostatic mankhwala trophosphamide,
• angapo antidepressants
• sulfonamides,
• mankhwala angapo omwe akufuna kutsitsa cholesterol,
• tetracycline mankhwala opha tizilombo,
• kukonzekera kutengera somatostatin ndi mayendedwe ake,
• othandizira a hypoglycemic
• chakudya chilolezo fenfluramine,
• antitumor mankhwala ifosfamide.

Kusamala kumafuna kumwa mankhwala potengera msuzi wa salicylic acid, tritokvalin, cyclophosphamide, guanethidine ndi phentolamine.

Mchere wa Lithium ukhoza kusintha kapena kuwonjezera phindu la mankhwalawo. Reserpine ndi clonidine amasiyana mu zomwezo.

Kugwiritsa ntchito ma beta-blockers kumawonjezera chiopsezo cha zovuta.

Zochita zamankhwala osokoneza bongo

Mankhwala angapo amatha kuthana ndi kagayidwe ka glucose ndikuwapangitsa kusintha kwa insulin kwa anthu.

Kukonzekera komwe kumathandizira hypoglycemic zotsatira za insulin ndikuwonjezera chiwopsezo pakukula kwa hypoglycemia kumaphatikizira antidiabetesic agents, angiotensin-converting enzyme (ACE) inhibitors, disopyramides, fibrate, fluoxetine, monoamine oxidase inhibitors (MAOs), pentoxitely pylxyllifesion, pentoxitely.

Mankhwala omwe amatha kufooketsa mphamvu ya hypoglycemic ya insulini amaphatikiza mahomoni a corticosteroid, danazole, diazoxide, diuretics, glucagon, isoniazid, estrogens ndi progestogens (mwachitsanzo, mu njira zakulera zogwiritsira ntchito pakamwa), phenothiazine zotumphukira, somatropin, epathy, epathy, epathy. salbutamol, terbutaline, mahomoni a chithokomiro, protease inhibitors ndi atypical antipsychotic mankhwala (mwachitsanzo, olanzapine ndi clozapine).

Beta blockers, clonidine, mchere wa lifiyamu ndi mowa zimatha kukulitsa ndikuchepetsa mphamvu ya insulin.

Pentamidine imatha kuyambitsa hypoglycemia, yomwe nthawi zina imasinthidwa ndi hyperglycemia.

Kuphatikiza apo, mothandizidwa ndi mankhwala achifundo ngati β-blockers, clonidine, guanethidine ndi reserpine, zizindikiro za adrenergic antiregulation zitha kukhala zofatsa kapena zosakhalapo.

Pharmacokinetics

Mwa anthu athanzi lathunthu, T ½ plasma insulin ndi pafupifupi mphindi 4-6. Odwala omwe ali ndi vuto losakwanira la impso, amatenga nthawi yayitali.

Ngakhale ziyenera kudziwika kuti pharmacokinetics ya insulin sichitulutsa metabolic yayo. Insulin imalimbikitsidwa kuti ichitidwe mankhwala a insulin omwe amafuna matenda a shuga.

Contraindication ndi mankhwala Bazal

• Hypersensitivity reaction insulin kapena othandizira ena a Insuman Bazal GT. Zosiyanazo ndizomwezo nthawi zina ngati sizingatheke popanda chithandizo cha insulin.

Mosamala kwambiri, muyenera kumwa mankhwalawa:

1. odwala okalamba, popeza kuchepa kwa ntchito ya impso kumabweretsa kuchepa kwa kufunika kwa insulin, ndipo izi zikuchitika,
2. Kulephera kwaimpso (chifukwa cha kuchepa kwa insulin metabolism mwa odwala, kufunika kwa insulin kumachepa),
3. Kulephera kwa chiwindi (chifukwa cha kuchepa kwa insulin metabolism komanso kuchepa kwa mphamvu ya thupi yogwiritsira ntchito gluconeogeneis, kufunika kwa insulini kumatha kuchepa),
4. stenosis yayikulu ya ubongo ndi mtima
5. odwala omwe akukhala ndi retinopathy ochulukirachulukira, makamaka omwe sanalandire chithandizo ndi laser mankhwala (Photocoagulation). Odwala awa omwe ali ndi hypoglycemia ali pachiwopsezo cha kusakhalitsa amaurosis (khungu lathunthu),
6. odwala omwe ali ndi ma pathologies omwe amagwirizana, muzochitika izi, odwala nthawi zambiri amawonjezera kufunikira kwa insulin.

Kwa matenda aliwonse omwe alembedwa pamwambapa, musanayambe kugwiritsa ntchito mankhwalawa, muyenera kufunsa dokotala.

Basal pa mimba ndi mkaka wa m`mawere

Ngakhale panthawi yoyembekezera, chithandizo ndi Insuman ® Bazal GT sichiyenera kusokonezedwa. Izi ndizotetezeka kwathunthu, chifukwa insulini siyitha kulowa mu zotchinga.

Ndipo kwa mzimayi yemwe anali ndi matenda ashuga asanatenge pathupi kapena yemwe analandila, kuwongolera kwa kagayidwe koyenera panthawi ya bere ndikofunika kwambiri.

Munthawi yoyamba kubereka, kufunika kwa insulini kumatha kuchepa, ndipo panthawi yachiwiri ndi yachitatu yomwe amatenga pathupi, nthawi zambiri imadzuka. Kufunika kwa insulin kumachepa ndipo atangobereka, mayi amakhala ndi chiopsezo chotenga hypoglycemia.

Nthawi yonse yomwe ali ndi pakati komanso pambuyo pobereka, kuchuluka kwa shuga wamagazi kuyenera kuyang'aniridwa mosamala. Pokonzekera kubereka ndi kutha kwake, mkazi ayenera kudziwitsa dokotala za izi.

Panthawi yoyamwitsa, palibe zoletsa pazamankhwala a insulin, ngakhale kusintha kwa mankhwalawa kungafunike.

Zotsatira zoyipa za mankhwalawa

Zotsatira zoyipa kwambiri za insulin mankhwala ndi hypoglycemia. Itha kuchitika ngati mlingo wa insulin upambana kwambiri kufunika kwake. Mobwerezabwereza zoopsa za hypoglycemia kumabweretsa kukula kwa zizindikiro zamitsempha: chikomokere, kukomoka.

Ziwopsezo zambiri komanso zachikale za hypoglycemia zitha kuwononga moyo wa odwala. Wodwalayo asanayambe kukhala ndi vuto la neuroglycemia, amakhala ndi chiwonetsero chazomwe zimayambitsa mantha amanjenje. Uku ndikuyankha kukulitsa hypoglycemia.

Nthawi zambiri, ndi kuchepa msanga komanso kutchulidwa kwambiri m'magazi a shuga, zizindikiritso za Reflex activation zam'maso achisoni ndi chodabwitsa chake zimawonekera kwambiri.

Ndi kuchepa kwambiri kwa shuga m'magazi, hypoglycemia kapena edema ya ubongo imatha kuyamba. Zomwe zalembedwa pano ndizovuta zomwe zingachitike mwa odwala. Amasankhidwa ndi magulu a gulu:

1. kuchuluka kwake sikudziwika (malinga ndi zomwe zilipo, sizingatheke kudziwa kuchuluka kwa zotsatira zoyipa),
2. chosowa kwambiri (kuchokera ku chitetezo chamthupi

• Kuwonetsedwa kwa thupi lawo kwamtundu wapadera mwachindunji pa insulin kapena pa okonda mankhwala - mafupipafupi sadziwika.
• Bronchospasms - pafupipafupi sadziwika.
• Zosintha khungu mosiyanasiyana - pafupipafupi sikudziwika.
• Kutsika kwa magazi - pafupipafupi sikudziwika.
• Angioneurotic edema - pafupipafupi sikudziwika.
• Kugwedeza kwa anaphylactic ndi njira yocheperako.
• Jakisoni wa insulin angayambitse antibodies ku insulin - pafupipafupi sikudziwika.

Zochitika zonsezi zitha kukhala zowopsa m'moyo wa wodwala, chifukwa chake, amafunikira thandizo mwachangu. Kukhalapo kwa ma antibodies mu nthawi zina kuti mukonzeke kungafune kusintha kwa insulin.

Pa mbali ya ziwalo zowoneka

1. Kusokoneza kwakanthawi kochepa kumatha kuchitika chifukwa cha kusintha kwa kayendetsedwe ka glycemic - pafupipafupi sikudziwika. Vutoli limayamba chifukwa cha kusinthasintha kwakanthawi kwa magalasi amaso ndi cholozera wawo.
2. Kuchepetsa kwambiri mankhwala a insulin ndi kuwongolera glycemic control kungawonedwe ngati kuchepa kwakanthawi kwa matenda ashuga retinopathy - mafupikiridwe sakudziwika.
3. Odwala omwe ali ndi proliferative retinopathy (makamaka kwa iwo omwe salandira chithandizo cholondola ndi mankhwala a laser), zochitika zazikulu za hypoglycemic zingayambitse kutayika kwathunthu kwamawonedwe (osakhalitsa amaurosis) - mafupipafupi sadziwika.

Zowonongeka pamalo opangira jekeseni komanso zovuta zina

Zochitika zofatsa zimakonda kupezeka m'malo a jakisoni. Mulinso:

• kupweteka m'dera la oyang'anira - pafupipafupi sikudziwika,
• redness pa jakisoni malo - pafupipafupi osadziwika
• urticaria m'dera loyang'anira - pafupipafupi sichikudziwika,
• kuyabwa m'dera loyang'anira - pafupipafupi sikudziwika,
• kutupa pamalo a jakisoni - pafupipafupi sikudziwika,
• Kutupa pamalo a jakisoni - pafupipafupi sikudziwika.

Ngakhale zochita zamphamvu kwambiri m'madzi a insulin m'malo a jakisoni nthawi zambiri zimatha patatha masiku angapo kapena milungu.

Malangizo ogwiritsira ntchito

Kukonzekera kwa insulin komwe kuyenera kugwiritsidwa ntchito, kuchuluka kwa shuga m'magazi, kuchuluka kwa insulini (nthawi ya jakisoni ndi mlingo) kuyenera kukhazikitsidwa ndikusintha payekhapayekha. Izi ndizofunikira kutsatira:

• moyo wodwala
• mulingo wakuchita zolimbitsa thupi
• chakudya.

Palibe malamulo okhazikitsidwa ndi mlingo wa insulin. Komabe, pali pafupifupi insulin yomwe imakhala ya 0.5-1 IU / kg / s. Pafupifupi 40% mpaka 60% ya tsiku ndi tsiku insulin yomwe munthu amafunika.

• Zokhudza kusintha kulikonse kwamalamulo a insulin,
• Zokhudza kusintha kwa zakudya,
• ndi pafupipafupi kudziwa kuchuluka kwa shuga m'magazi.

Kusintha kuchokera ku Bazal

Posamutsa wodwala kuchokera ku insulin imodzi kupita ku insulin ina, kuwongolera kwa kuchuluka kwa mahomoni kungakhale kofunikira. Itha kukhala:

• kusinthana ndi insulin yaumunthu kuchokera ku insulin yoyambira nyama,
• Kusintha kwa kapangidwe ka insulin ya munthu kupita kwina,
• kapena mukamasintha kuchokera ku mankhwala osungunuka a insulin ya anthu kupita ku regimen yomwe imaphatikizapo kugwiritsa ntchito insulin yayitali.

Pakusintha insulin yakuchokera kwa nyama kukhala insulin yaumunthu, zingakhale zofunikira kuti muchepetse mlingo wake.

Izi ndizofunikira makamaka kwa odwala omwe:

• m'mbuyomu anali otsika kwambiri shuga
• chifukwa cha kukhalapo kwa ma antibodies a insulin, milingo yake yayikulu idagwiritsidwa ntchito kale,
• khalani ndi chidwi pakukula kwa hypoglycemia.

Kufunika kochepetsa mlingo kumatha kuonekera mukangosintha mtundu wina wa insulin, ndipo kumatha kuyamba pang'onopang'ono (masabata angapo). Panthawi yosintha kuchokera ku insulin imodzi kupita kwina, komanso milungu ingapo yotsatira, kuyang'anira magazi a shuga ndikofunikira.

Odwala omwe, chifukwa cha kupezeka kwa antibodies, agwiritsa ntchito kuchuluka kwa insulin, ayenera kusinthana ndi mtundu wina wa insulin kokha kuchipatala moyang'aniridwa ndi achipatala mosamalitsa.

Kusintha kwa Mlingo

Kuchuluka kwa insulivivity kumatha kuchitika chifukwa cha kuwongolera kwa metabolic. Zotsatira zake, kufunikira kwa insulin kumatha kuchepa.

Kusintha kwa mlingo kungakhale kofunikira pazinthu zina:

• kusintha kwa thupi la wodwala,
• Kusintha kwamachitidwe, kuphatikiza zolimbitsa thupi ndi zakudya,
• zochitika zomwe zimathandizira kukulitsa kwa hyper- ndi hypoglycemia.

Mlingo wothandizidwa ndi magulu apadera a odwala

1. Okalamba - m'gululi, pakapita nthawi, kufunika kwa insulin kumatha kuchepa. Chifukwa chake, yambani mankhwala a insulin, sankhani mankhwala okonza kapena kuwonjezera kuchuluka kwa odwala okalamba omwe ali ndi matenda ashuga ayenera kusamala kwambiri. Kupanda kutero, zotsatira za hypoglycemic zitha kupsa mtima.
2. Odwala aimpso kapena kwa chiwindi.Anthu awa, nawonso, angafunikire insulini yocheperako.

Jakisoni wa mankhwala

Basal nthawi zambiri imathandizira kwambiri, mphindi 45-60 asanadye. Nthawi iliyonse ndikulimbikitsidwa kuti musinthe jekeseni mkati mwa gawo lomwelo. Mwachitsanzo, pamimba amasintha kukhala m'chiuno. Koma kusintha kumeneku kumatheka pokhapokha atakambilana ndi dokotala.

Izi ndizofunikira chifukwa adsorption ya insulin, ndipo chifukwa chake kutsitsa shuga m'magazi, imatha kusinthasintha kutengera (mwachitsanzo, ntchafu kapena pamimba).

Bazal sagwiritsidwe ntchito mitundu yosiyanasiyana ya mapampu a insulin (kuphatikizapo mapampu amadzalo). Mothandizidwa ndi mtsempha wa magazi sizovomerezeka! Ndizosatheka kuloleza kusakanikirana kwa Bazal ndi insulin analogues, insulin ya nyama, insulin ya ndende ina komanso mankhwala ena.

Basal ikhoza kusakanikirana ndi mtundu uliwonse wa insulin yaumunthu yomwe Sanofi-aventis Gulu limatulutsa. Koma ndi insulin, yopangidwira mapampu a insulin, Bazal sayenera kusakanikirana konse.

Nthawi zonse muyenera kukumbukira kuti kuchuluka kwa insulini kuli pa chiwerengero cha 100 IU / ml (ma cartridge 3 ml kapena ma ml 5). Chifukwa chake muyenera kugwiritsa ntchito mapensulo a syringe a KlikSTAR kapena OptiPen Pro1 (ngati makatiriji ogwiritsidwa ntchito), kapena syringes pulasitiki yomwe izi.

Mu syringe ya pulasitiki sangakhale mankhwala ena alionse kapena zotsalira zake. Pakusunga insulin kuchokera ku vial koyamba, kapu ya pulasitiki iyenera kuchotsedwa komaliza. Kupezeka kwake kukuwonetsa kuti botolo silinatsegulidwe kale.

Zizindikiro za mankhwala osokoneza bongo

Kuyambitsa insulin yochuluka kwambiri, ndiye kuti, yochuluka kwambiri yaiyo poyerekeza ndi ndalama zamagetsi kapena zakudya zomwe zimagwiritsidwa ntchito, zimatha kuyambitsa hypoglycemia ya nthawi yayitali.

Dzina lachi Latin: Insuman basal gt
Code ya ATX: A10A C01
Chithandizo: Isofan
Wopanga: Sanofi-Aventis (Germany)
Matchuthi ku pharmacy: Ndi mankhwala
Malo osungira: pa ° 2-8 ° C
Tsiku lotha ntchito: Miyezi 24

Insuman Bazal-GT ndi insulin mankhwala a nthawi yayitali. Amasankhidwa kuti azilamulira glycemia mwa odwala matenda a shuga.

The zikuchokera ndi Mlingo mawonekedwe a mankhwala

Mu 1 ml - 100 mg ya bioengineered insulin.

Zowonjezera zina: protamine sulfate, m-cresol, phenol, zinc chloride, glycerol, caustic soda, hydrochloric acid, madzi, ndi zina.

Mankhwala osokoneza bongo ngati oyera kapena oyera, omasukirana mosavuta, kuyimitsidwa kuti apangidwe jakisoni. Amayikika m'matambula agalasi oikidwa mu zolembera kapena mabotolo otayidwa, okhala ndi timiyulu. Mu paketi yonyamula makatoni: 5 mas. (3 ml iliyonse) kapena Mbale zisanu (5 ml iliyonse), zosafunikira.

Zizindikiro zogwiritsidwa ntchito

• wodwala matenda ashuga
• acidosis
• shuga mellitus chifukwa cha zinthu zosiyanasiyana: opareshoni, matenda omwe amatsatiridwa ndi malungo, omwe ali ndi vuto la metabolic, atabereka mwana.
• predkomatoznoe mkhalidwe, womwe ndi chifukwa cha kusakhalitsa kwa chikumbumtima, gawo loyamba la chitukuko cha chikomokere.

• insulin yodalira matenda a shuga
• shuga yokhazikika yokhala ndi zosowa zochepa za insulin,
• kuchitira ena mwankhanza chithandizo.

Kuyenderana ndi mowa

Mwa uchidakwa woperewera, kuchuluka kwa glycemia kumasintha. Ndi matenda ashuga, kulolera mowa kumachepa, ndipo kufunsa kwa dokotala ndikofunikira pankhani ya kumwa moledzera. Kuchulukitsa kwa glucose kumatha kutsika kwambiri.

Mukatha kugwiritsa ntchito koyamba, botolo limatha kusungidwa kwa maola 4, cartridge - kwa masiku 28 mutatha kuyika. Pakusunga, kuyatsa kuwala kuyenera kupewedwa ndipo kutentha sikuyenera kuloledwa kukwera pamwamba + 25 ° C.

Makanema okhudzana nawo

About nuances of use of insulin mankhwala Insuman Rapit ndi Basal mu kanema:

Insuman imagwiritsidwa ntchito pochiza odwala matenda a shuga mellitus.Ndizofanana ndi insulin yaumunthu. Amachepetsa shuga ndipo amapangitsa kuchepa kwa insulin. Amapezeka ngati yankho lomveka bwino la jakisoni. Mlingo, monga lamulo, umaperekedwa kwa wodwala aliyense payekhapayekha, wowerengeredwa pamaziko a mawonekedwe a matendawa.

Mphamvu yogwira: 1 ml ya kuyimitsidwa imakhala ndi 100 ME (3.571 g) ya insulin yaumunthu. Omwe amathandizira: protamine sulfate, m-cresol, phenol, zinc chloride, sodium dihydrogen phosphate dihydrate (E339), glycerol 85% (E422), sodium hydroxide (E524), madzi owonjezera a hydrochloric acid (E507), madzi a jakisoni.

Mimba komanso kuyamwa

Palibe maphunziro azachipatala omwe amagwiritsidwa ntchito popanga insulin yaumunthu panthawi yapakati. Insulin siyidutsa chotchinga. Popereka mankhwala kwa amayi apakati, muyenera kusamala.

Pankhani ya odwala preexisting kapena gestationalabetes mellitus, ndikofunikira kusungabe kuchuluka koyenera kwa metabolic panthawi yonse yokhala ndi pakati. Kufunika kwa insulini mu nthawi yoyambirira ya kubereka kumatha kuchepa, koma m'nthawi yachiwiri ndi yachitatu matupi awo amakula. Pambuyo pobadwa, insulin imafunikira imatsika mofulumira (chiwopsezo chowonjezereka cha hypoglycemia). Kuwunikira mosamala kuchuluka kwa shuga m'magazi kumafunika.

Panthawi yoyamwitsa, palibe malamulo oletsa insulin. Komabe, mlingo wa insulin komanso kusintha kwa zakudya kungafunike.

Zotsatira zoyipa

Hypoglycemia, njira yodziwika bwino kwambiri, imatha kupezeka ngati mlingo wa insulin woperekedwa umapitilira kufunikira kwake. Sizingatheke kufotokoza kuchuluka kwa vuto la hypoglycemia, chifukwa kufunika kwa mayesero azachipatala komanso kugwiritsa ntchito mankhwala ogulitsa kumatha kusiyanasiyana malinga ndi kuchuluka kwa anthu komanso kuchuluka kwake. Zochitika zazikuluzikulu za hypoglycemia, makamaka ngati zibwerezedwa, zimatha kuyambitsa kukulitsa kwa mitsempha, kuphatikizapo chikomokere, kukokana. Nthawi zina, zochitika ngati izi zitha kupha.

Odwala ambiri, zizindikiro za kuwonongeka kwa hypoglycemic kwa chapakati mantha amayamba ndi zizindikiro za kutsutsana ndi adrenergic. Monga lamulo, pamene kuchuluka kwa glucose m'magazi kumachepera, ndiye kuti tanthauzo la kutsutsana ndi zizindikiro zake.

Zotsatira zotsatirazi zotsutsana ndi kugwiritsa ntchito mankhwalawa ndikuwonetsedwa m'mayesero azachipatala amalembedwa ndi magulu a ziwalo zamankhwala komanso kuchepa kwa zochitika: zofala kwambiri (> 1/10), zofala (> 1/100, 1 / 1.000, 1/10000 ,

Wopanga

Mankhwalawa amapangidwa ndi Sanofi-Aventis. Dziko lopanga limatha kukhala Germany kapena Russia.

Insulin amakonzekera Insuman Rapid ndi Insuman Bazal

Fomu ya Mlingo: Jekeseni yankho

1 ml yankho lili:

ntchito yogwira : insulin ya anthu (100% sungunuka wa munthu insulin) 3,571 mg (100 ME),

zokopa: metacresol (m-cresol) 2.700 mg, sodium dihydrogen phosphate dihydrate 2.100 mg, glycerol (85%) 18.824 mg, sodium hydroxide (amagwiritsidwa ntchito kusintha pH) 0,576 mg, hydrochloric acid (amagwiritsidwa ntchito kusintha pH) 0,232 mg, madzi a jakisoni 1 , 0 ml.

Kufotokozera: Madzi owoneka bwino, opanda khungu. Gulu la Pharmacotherapeutic: wothandizira wa hypoglycemic - wothandizira insulin ATX: & nbsp

A.10.A.B.01 Insulin (munthu)

Insuman® Rapid GT imakhala ndi insulini yofanana ndi insulin yaumunthu ndipo yopezeka ndi mainjiniya ogwiritsa ntchito mtundu wa K12 E. Coli .

Limagwirira zake insulin:

Amachepetsa kuchuluka kwa shuga m'magazi, amalimbikitsa zotsatira za anabolic komanso amachepetsa zotsatira za catabolic,

Zimawonjezera kuyendetsa shuga mkati mwa maselo ndikupanga glycogen mu minofu ndi chiwindi ndikuwongolera kugwiritsa ntchito pyruvate, tikuletsa glycogenolysis ndi glyconeogeneis,

Kuchulukitsa lipogenesis mu chiwindi ndi adipose minofu ndi ziletsa lipolysis,

Zimalimbikitsa kutulutsa kwa ma amino acid m'maselo ndi kaphatikizidwe wa mapuloteni,

Kuchulukitsa kwa potaziyamu kumaselo.

Insuman® Rapid GT ndi insulini yomwe imayamba mwachangu komanso nthawi yayitali. Pambuyo pakuyang'aniridwa kwa subcutaneous, zotsatira za hypoglycemic zimachitika pakatha mphindi 30 ndikufika pazokwanira mkati mwa maola 1-4. Zotsatira zimatha kwa maola 7-9.

Matenda a shuga odwala matenda a insulin

Chithandizo cha matenda ashuga komanso ketoacidosis,

Kukwaniritsa kulipira kwa metabolic kwa odwala omwe ali ndi matenda osokoneza bongo nthawi ya opaleshoni (asanachitike opaleshoni, panthawi ya opaleshoni komanso nthawi ya postoperative).

Hypersensitivity reaction insulin kapena chilichonse chothandiza cha mankhwala.

Kulephera kwa aimpso (mwina kuchepa kwa insulin chifukwa cha kuchepa kwa insulin metabolism),

Odwala okalamba (kuchepa kwapang'onopang'ono kwaimpso kungayambitse kuchepa kwa insulin kosowa),

Odwala omwe ali ndi vuto la chiwindi (kufunika kwa insulin kumatha kuchepa chifukwa cha kuchepa kwa mphamvu ya gluconeogeneis ndi kuchepa kwa insulin metabolism),

Odwala omwe ali ndi stenosis yamphamvu kwambiri yam'mimba komanso matenda amitsempha yama cell (hypoglycemic episode amatha kukhala ndi chidwi chapadera chachipatala, chifukwa pali chiopsezo cha mtima kapena matenda a mtima) a hypoglycemia

Odwala omwe ali ndi retinopathy yowonjezereka, makamaka omwe sanalandire chithandizo ndi Photocoagulation (laser therapy), popeza ali ndi chiopsezo chochepa kwamayurosis okhala ndi hypoglycemia wathunthu - khungu lathunthu,

Odwala omwe ali ndi matenda ophatikizana (popeza matenda omwe amakumana nawo nthawi zambiri amawonjezera kufunika kwa insulin).

Mimba ndi kuyamwa:

Chithandizo cha Insuman® Rapid GT panthawi yoyembekezera ziyenera kupitilizidwa. Insulin siyidutsa chotchinga.

Kusunga moyenera kagayidwe kazakudya panthawi yonse yoyembekezera ndikovomerezeka kwa azimayi omwe ali ndi matenda ashuga asanabadwe, kapena amayi omwe apanga matenda a shuga.

Kufunika kwa insulin panthawi yapakati kumatha kuchepa panthawi yayitali ya kubereka ndipo nthawi zambiri kumawonjezeka panthawi yachiwiri komanso yachitatu ya kutenga pakati. Pambuyo pobadwa, insulini ikucheperachepera (chiwopsezo cha hypoglycemia). Pa nthawi ya pakati komanso makamaka mukabereka mwana, kuwunika mosamala kuchuluka kwa shuga m'magazi kumafunika.

Ngati muli ndi pakati kapena mukufuna kubereka, onetsetsani kuti mwadziwitsa dokotala.

Munthawi ya kuyamwitsa, palibe zoletsa pazamankhwala a insulin, komabe, kusintha kwa mlingo, insulin ndi zakudya zingafunike.

Mlingo ndi makonzedwe:

Cholinga cha shuga m'magazi, kukonzekera kwa insulin komwe kumayenera kugwiritsidwa ntchito, njira ya insulin dosing (mlingo ndi nthawi ya makonzedwe) iyenera kutsimikizika ndikusintha payekhapayekha kuti mugwirizane ndi chakudya, mulingo wakuchita zolimbitsa thupi komanso moyo wa wodwalayo.

Palibe malamulo oyendetsedwa bwino a insulin. Komabe, pafupifupi tsiku lililonse insulin ndi 0,5-1.0 INI pa kilogalamu ya thupi patsiku, ndipo insulin ya anthu yayitali imakhala ndi 40-60% ya kuchuluka kwa insulin tsiku lililonse.

Dokotala amayenera kupereka malangizo ofunikira kuti azindikire kuchuluka kwa shuga m'magazi, komanso apereke malangizo oyenera pazosintha zilizonse m'zakudya kapena muyezo wa insulin.

Mankhwalawa kwambiri hyperglycemia kapena, makamaka ketoacidosis, insulin makonzedwe ndi gawo limodzi la machitidwe azachipatala omwe amaphatikiza njira zoteteza odwala ku zovuta zazikulu chifukwa cha kuchepa kwambiri kwa ndende yamagazi. Malangizo a mankhwalawa amafunika kuwunika mosamalitsa m'chipinda chopangira chisamaliro (kudziwa kagayidwe kazinthu, acid-base olimba ndi electrolyte bwino, kuwunika zofunikira za thupi).

Kusintha kuchokera ku mtundu wina wa insulin kupita ku Insuman® Rapid GT

Posamutsa wodwala kuchokera ku mtundu wina wa insulin kupita ku wina, kagwiritsidwe ntchito ka mankhwalawo a insulin: mwina mukasintha kuchokera ku insulin yochokera ku nyama kupita ku insulin yaumunthu, kapena mukasintha njira ina yopangira insulin yaumunthu kupita ku ina. , kuphatikizapo insulin.

Pambuyo pakusintha kuchokera ku insulin yochokera ku nyama kupita ku insulin ya anthu, mwina pangafunike kuchepetsa kuchuluka kwa insulin, makamaka kwa odwala omwe kale anali ndi zovuta zamagazi, odwala omwe ali ndi chizolowezi chokhala ndi hypoglycemia, mwa odwala omwe kale amafuna kuchuluka kwa insulin yayikulu chifukwa cha ndi kukhalapo kwa ma antibodies ku insulin.

Kufunika kosinthira kwa mlingo (kuchepetsa) kumatha kuchitika mukangosintha mtundu watsopano wa insulin kapena kuyamba pang'onopang'ono milungu ingapo.

Mukasintha kuchokera ku mtundu wina wa insulini kupita ku wina kenako m'milungu yoyamba yotsatira, kuyang'aniridwa mosamala kwa shuga wamagazi ndikulimbikitsidwa. Odwala omwe amafuna kwambiri Mlingo wa insulin chifukwa cha antibodies, tikulimbikitsidwa kusinthana ndi mtundu wina wa insulin moyang'aniridwa ndi achipatala kuchipatala.

Kusintha kowonjezera kwa insulin

Kuwongolera kagayidwe ka metabolic kumatha kuyambitsa chidwi cha insulini, zomwe zingapangitse kuchepa kwa kufunika kwa insulin.

Kusintha kwa mlingo kungafunikenso ngati:

Zosintha pamlingo wa wodwala,

Kusintha kwamoyo (kuphatikizapo zakudya, kuchuluka kwa zolimbitsa thupi, ndi zina).

Nthawi zina zomwe zimapangitsa kuti chiwopsezo cha hypo- kapena hyperglycemia chidziwike (onani “Malangizo Apadera”).

Mlingo wampingo wamagulu apadera odwala

Anthu okalamba

Kwa anthu achikulire, kufunikira kwa insulini kumatha kuchepa (onani magawo "Mosamala", "Malangizo apadera"). Ndikulimbikitsidwa kuti kuyambitsidwa kwa chithandizo, kuyamwa kwa mankhwalawa ndikusankha mankhwalawa kwa odwala okalamba omwe ali ndi matenda osokoneza bongo kuchitike mosamala kuti popewa kukhudzana ndi hypoglycemic.

Odwala omwe ali ndi chiwindi kapena aimpso kulephera

Odwala omwe ali ndi vuto la hepatic kapena aimpso, kufunika kwa insulin kungachepe.

Kupanga kwa Insuman® Rapid GT

Insuman® Rapid GT nthawi zambiri imaperekedwa kwa mphindi 15-20 asanadye chakudya. Tsamba la jakisoni mkati mwa jekeseni lomwelo limayenera kusinthidwa nthawi iliyonse. Kusintha gawo la kayendetsedwe ka insulini (mwachitsanzo, kuyambira pamimba mpaka m'chafu) kuyenera kuchitika pokhapokha kukaonana ndi dokotala, popeza kuyamwa kwa insulini ndipo, chifukwa chake, kuchepetsa kwazovuta zamagazi m'magazi kumatha kusiyanasiyana malingana ndi dera loyang'anira.

Insuman® Rapid GT imatha kutumikiridwa kudzera m'mitsempha. Intravenous insulin Therapy iyenera kuchitika kuchipatala kapena m'malo omwe kuwunika kofananirako ndi chithandizo kungalandire.

Insuman® Rapid G "T sagwiritsidwa ntchito pamapampu amtundu wa insulin ambiri (kuphatikizapo omwe adalowetsedwa) momwe timachubu ta silicone timagwiritsidwa ntchito.

Osasakaniza Insuman® Rapid GT ndi insulin ya ndende ina, ndi insulin yakuchokera kwa nyama, ma insulin analogi kapena mankhwala ena.

Insuman® Rapid GT ikhoza kusakanizika ndi magulu onse amakono a insulin-aventis. Insuman® Rapid GT siyenera kusakanikirana ndi insulin yomwe cholinga chake amagwiritsidwe ntchito pamapampu a insulin.

Kumbukirani kuti kuchuluka kwa insulin m'makonzedwe a Insuman® Rapid GT ndi 100 MG / ml (kwa ma ml 5 kapena ma cartilges 3 ml), motero ndikofunikira kugwiritsa ntchito ma syringes apulasitiki omwe amapangidwira insulin iyi chifukwa chogwiritsa ntchito mbale, kapena ma cholembera a sytiiten a OptiPen Pro1 kapena ClickSTAR ngati mugwiritsa ntchito makatoni. Syringe ya pulasitiki siyenera kukhala ndi mankhwala ena aliwonse kapena zotsalira zake.

Pamaso gawo loyambirira la insulin kuchokera pambale, chotsani pulasitiki (kukhalapo kwa kapuyo ndi umboni wa vial wosatsutsana).

Njira yothetsera jakisoni iyenera kukhala yowonekera bwino komanso yopanda utoto popanda ma cell akunja owoneka.

Asanatenge insulini kuchokera ku vial, mpweya wofanana ndi mankhwala omwe amaperekedwa ndi insulin umayamwa mu syringe ndikujowina mu vial (osalowa madzi). Kenako vala yokhala ndi syringe imasinthidwa mozungulira ndi syringe ndipo kuchuluka kwa insulini kumatengedwa. Pamaso jakisoni, chotsani thovu lakumanzere mu syringe.

Khungu limatengedwa pamalo a jakisoni, singano imayikidwa pansi pakhungu, ndipo insulin imayamwa pang'onopang'ono. Pambuyo pa jekeseni, singano imachotsedwa pang'onopang'ono ndipo tsamba lamalowo limakanikizidwa ndi swab ya thonje kwa masekondi angapo. Tsiku lokhala ndi insulin kit kuchokera pa vial iyenera kulembedwa pa cholembera cha vial.

Mutatsegula mabotolo amatha kusungidwa pa kutentha osaposa + 25 ° C kwa masabata anayi pamalo otetezedwa ku kuwala ndi kutentha.

Musanalowetse cartridge (100 MN / ml) mu cholembera cha sytinge ya OptiPen Pro1 ndi KlikSTAR, gwiritsani ntchito kwa maola 1-2 kutentha kwa chipinda (jakisoni a insulin yodziwika bwino kwambiri. Chotsani zotumphukira zilizonse zamagetsi pamkatikati musanabayidwe (onani Malangizo pakugwiritsa ntchito zolembera za OptiPen Pro1 kapena ClickSTAR syringe).

Katoniyo sanapangire kusakaniza Insuman® Rapid GT ndi ma insulini ena. Makatoni opanda kanthu sangakwaniritsidwe.

Pakuswa phala la syringe, mutha kulowa muyezo wofunika kuchokera pa cartridge pogwiritsa ntchito syringe yachizolowezi. Kumbukirani kuti kuchuluka kwa insulini mu cartridge ndi 100 IU / ml, kotero muyenera kugwiritsa ntchito syringes zapulasitiki zopangidwira insulin. Syringe siyenera kukhala ndi mankhwala ena aliwonse kapena zotsalira zake.

Pambuyo kukhazikitsa cartridge, itha kugwiritsidwa ntchito milungu 4.

Ndikulimbikitsidwa kusungitsa cholembera ndi makatoni omwe amaikidwa pa kutentha osaposa + 25 ° C pamalo otetezedwa ku kuwala ndi kutentha, koma osati mufiriji (popeza jakisoni wodziwika ndi insulin yovuta kwambiri).

Mukayika makatoni atsopano, yang'anani ntchito yoyenera ya cholembera usanalowe jekeseni woyamba (onani Malangizo Ogwiritsira Ntchito OptiPen Pro1 Syringe Pens kapena ClickSTAR). Insuman® Rapid GT, yankho la jakisoni mu cholembera yotayika SoloStar® limangokhala kokha kwa makina osokonekera.

Hypoglycemia, zotsatira zoyipa kwambiri za mankhwala a insulin, amatha kupezeka ngati mlingo wa insulin womwe umayendetsedwa upambana pazofunikira zake (onani "Maupangiri Apadera"). Magawo obwerezabwereza a hypoglycemia angayambitse kukulira kwa minyewa, kuphatikizapo chikomokere (onani gawo "Overdose"). Kukhalitsa kwa nthawi yayitali kapena koopsa kwa hypoglycemia kumatha kukhala pachiwopsezo cha moyo.

Odwala ambiri, zizindikiro ndi mawonekedwe a neuroglycopenia atha kukhala patsogolo ndi zizindikiro za Reflex (poyankha kukulitsa hypoglycemia) kutsegulira kwa mtima wamanjenje.Nthawi zambiri, ndi kuchepa kwambiri kapena kuchepa msanga kwa kuchuluka kwa shuga m'magazi, chodabwitsa cha kutseguka kwa mphamvu yamanjenje yomvera chisoni ndikuonetsa zizindikiro zake.

Ndi kuchepa kwakukulu kwa kuchuluka kwa shuga m'magazi, kukulitsa kwa hypokalemia (zovuta kuchokera ku mtima) kapena kukula kwa edema yamatumbo.

Otsatirawa ndi zochitika zoyipa zomwe zimayesedwa m'magulu oyeserera omwe amalembedwa ndi magulu a organic ndi kuchepa kwa zochitika: pafupipafupi kwambiri (≥1 / 10), pafupipafupi (≥1 / 100, ndi zomwe zimachitika pang'ono pakamanena za insulin pamalo a jekeseni nthawi zambiri zimatha. m'masiku ochepa kapena masabata angapo.

Mankhwala osokoneza bongo a insulin ambiri, monga kupereka insulin yochulukirapo poyerekeza ndi chakudya kapena mphamvu zomwe zimagwiritsidwa ntchito, amathanso kukhala ndi vuto la hypoglycemia lomwe limatenga nthawi yayitali.

Zochitika zofatsa za hypoglycemia (wodwalayo amadziwa) zitha kuyimitsidwa ndikutenga chakudya mkati. Kusintha kwa mlingo wa insulin, kudya, komanso zolimbitsa thupi kungafunike.

Ziwonetsero zoopsa za hypoglycemia ndi chikomokere, kukomoka kapena kuchepa kwa mitsempha zimatha kuyimitsidwa ndi kutsekeka kapena kupindika kwa glucagon kapena kulowetsedwa kwa njira yokhazikika ya dextrose. Mu ana, kuchuluka kwa dextrose kutumikiridwa kumayikidwa molingana ndi kulemera kwa thupi la mwana. Pambuyo pakuwonjezera kuchuluka kwa shuga m'magazi, kuthandizira kudya zakudya zamagulu ndi kuwunika kungafunike, popeza pambuyo poti kuchipatala chithetsa zizindikiro za hypoglycemia, kukhazikikanso kwake ndikotheka. Mlandu wa hypoglycemia wowopsa kapena wotalika potsatira jakisoni wa glucagon kapena dextrose, tikulimbikitsidwa kuti kulowetsedwa kuchitike ndi yankho lozama la dextrose pofuna kupewa kukonzanso kwa hypoglycemia. Mu ana aang'ono, ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magazi, molingana ndi chitukuko chachikulu cha hyperglycemia.

Kugwiritsira ntchito mosiyanasiyana ndi othandizira pakamwa a hypoglycemic, angiotensin kutembenuza ma enzyme inhibitors, disopyramide, fibrate, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, propoxyphene, salicylates, amphetamine, anabolic steroids ndi abambo phenylphosphamphometrate, hemclophosphinometrate, hemclophosphometormin, hemocorhlometromu, hosphorphormines. , somatostatin ndi mawonekedwe ake, sulfonamides, tetracyclines, tritocqualin kapena trophosphamide imatha kupititsa patsogolo hypoglycemic ya insulin ndikuwonjezera kudziwikiratu kwa chitukuko cha hypoglycemia.

The ntchito kuphatikiza a corticotropin, corticosteroids, danazol, diazoxide, okodzetsa, glucagon, isoniazid, estrogens ndi progestogens (monga kupezeka mu kulera zosiyanasiyanazi kuphatikiza), opangidwa kuchokera phenothiazine, kukula timadzi, mankhwala sympathomimetic (mwachitsanzo, wa epinephrine, salbutamol, terbutaline), chithokomiro timadzi, barbiturates, nicotinic acid, phenolphthalein, phenytoin zotumphukira, doxazosin itha kufooketsa mphamvu ya hypoglycemic ya insulin.

Beta-blockers, mchere wa lithiamu itha kukhala yopatsa mphamvu kapena kufooketsa mphamvu ya hypoglycemic ya insulin.

Ethanol imatha kukhala yothandiza kapena kufooketsa mphamvu ya insulin. Kudya kwa Ethanol kumatha kuyambitsa hypoglycemia kapena kuchepetsa shuga wambiri m'magazi kuti akhale owopsa. Kulekerera kwa Ethanol mwa odwala omwe amalandira insulin kumachepetsedwa. Mitundu yovomerezeka ya zakumwa ziyenera kutsimikiziridwa ndi dokotala.

Ndi makonzedwe munthawi yomweyo, kukulitsa kwa hypoglycemia ndikotheka, komwe nthawi zina kumatha kukhala hyperglycemia.

Mukamagwiritsa ntchito limodzi ndi othandizira ena, monga beta-blockers, guanethidine ndi, mwina kufooka kapena kusakhalapo kwathunthu kwa zizindikiro za Reflex (poyankha hypoglycemia) kutsegula kwa mtima wamanjenje.

Ngati vuto la glycemic likulephera kapena ngati matendawa ali ndi vuto la hyper- kapena hypoglycemia, musanaganize zosintha muyezo wa insulin, onetsetsani kuti mwalamulira insulin, onetsetsani kuti insulini idalowa mu malo omwe akutsimikiziridwa, yang'anani kulondola kwa njira ya jakisoni ndi zina zonse zomwe zingakhudze zotsatira za insulin.

Popeza kuperekera pamodzi kwa mankhwala angapo (onani gawo "Kuyanjana ndi mankhwala ena") kungafooketse kapena kuwonjezera mphamvu ya Hypoglycemic ya mankhwala a Insuman® Rapid GT, palibe mankhwala ena omwe ayenera kumwedwa popanda chilolezo chadokotala.

Hypoglycemia imachitika ngati mlingo wa insulin uposa kufunika kwake.

Chiwopsezo cha kukhala ndi hypoglycemia ndi chachikulu pamayambiriro a chithandizo cha insulin, mukasinthira kukonzekera kwina kwa insulin, mwa odwala omwe ali ndi shuga yayitali m'magazi.

Monga ndi ma insulin onse, chisamaliro chapadera chiyenera kutengedwa ndikuwunika kwambiri kuchuluka kwa shuga m'magazi omwe odwala hypoglycemic episode angakhale ndi vuto lapadera la matenda, monga odwala omwe ali ndi vuto lalikulu la mitsempha kapena matenda a mitsempha (chiwopsezo cha mtima kapena matenda a m'magazi a hypoglycemia), akulimbikitsidwa. , komanso odwala omwe ali ndi proliferative retinopathy, makamaka ngati sanachite nawo mankhwala opatsirana pogwiritsa ntchito mankhwala a laser, popeza ali ndi chiopsezo chocheperako amaurosis (kwathunthu khungu) ndi chitukuko cha hypoglycemia.

Pali zizindikiro ndi zodwala zina zomwe ziyenera kuwonetsa kwa wodwala kapena ena za kukhala ndi hypoglycemia. Izi zimaphatikizapo thukuta lomwe limakulirakulira, chinyezi pakhungu, tachycardia, kusokonezeka kwa mtima, kuchuluka kwa magazi, kupweteka pachifuwa, kunjenjemera, nkhawa, njala, kugona, kusokonezeka kwa tulo, mantha, kukhumudwa, kusazolowereka, zosadziwika bwino, nkhawa, paresthesia mkamwa ndi kuzungulira pakamwa, kutsekeka kwa khungu, kupweteka mutu, kusokonekera kwa kayendedwe ka kayendedwe, komanso kuchepa kwa minyewa yamitsempha yamagazi (kufooka kwa mawu ndi masomphenya, zizindikiro zakuwala) ndi zomveka zachilendo. Ndi kuchepa kowonjezereka: kutsekemera kwa shuga, wodwalayo atha kudziletsa komanso ngakhale kuzindikira. Zikatero, kuzizira ndi chinyezi pakhungu kumatha kuonedwa, ndipo kupweteka kumawonekeranso.

Chifukwa chake, wodwala aliyense yemwe ali ndi matenda a shuga omwe amalandila insulin ayenera kuphunzira kuzindikira zizindikiro zomwe ndi chizindikiro cha kukhala ndi hypoglycemia. Odwala omwe nthawi zonse amayang'anira kuchuluka kwa shuga m'magazi samatha kukhala ndi hypoglycemia. Wodwalayo amatha kuwongolera kuchepa kwa kuchuluka kwa shuga m'magazi ake mwa kuthira shuga kapena zakudya zamafuta ambiri. Pazifukwa izi, wodwalayo ayenera kukhala ndi 20 g shuga nthawi zonse. Mokulira kwambiri kwa hypoglycemia, jakisoni wokhazikika wa glucagon akuwonetsedwa (omwe angathe kuchitidwa ndi dokotala kapena antchito oyamwitsa). Pambuyo pakusintha kokwanira, wodwalayo ayenera kudya. Ngati hypoglycemia singathetsedwe mwachangu, ndiye kuti dokotala akuyenera kuyitanidwa mwachangu. Ndikofunikira kudziwitsa dokotala mwachangu za kukula kwa hypoglycemia kuti apange chisankho pakufunika kusintha kwa insulin. Kulephera kutsatira zakudya, kudumphira jakisoni wa insulin, kuchuluka kwa insulini chifukwa cha matenda opatsirana kapena matenda ena, komanso kuchepa kwa zochitika zolimbitsa thupi kungapangitse kuwonjezeka kwa ndende yamagazi (hyperglycemia), mwina ndi kuchuluka kwa matupi a ketone m'magazi (ketoacidosis). Ketoacidosis imatha kumatha maola ochepa kapena masiku. Pazizindikiro zoyambirira za metabolic acidosis (ludzu, kukodza pafupipafupi, kulephera kudya, kutopa, khungu lowuma, kupuma kwambiri komanso kuthamanga, chidwi cha acetone ndi glucose mkodzo), chithandizo chamankhwala chofunikira ndichofunikira.

Pakusintha dokotala (mwachitsanzo, nthawi yakuchipatala chifukwa cha ngozi, kudwala panthawi ya tchuthi), wodwalayo ayenera kudziwitsa dokotala kuti ali ndi matenda ashuga.

Odwala ayenera kuchenjezedwa za mikhalidwe yomwe ingasinthe, osatchulidwanso kapena kuchenjeza zizindikiro zosapezekeratu pakukula kwa hypoglycemia, mwachitsanzo:

Kusintha kwakukulu pakayendetsedwe ka glycemic,

Ndi kukula kwapang'onopang'ono kwa hypoglycemia,

Odwala okalamba,

Odwala omwe ali ndi vuto la neuronomic,

Odwala omwe ali ndi mbiri yayitali ya matenda ashuga,

Odwala omwe amalandira chithandizo nthawi yomweyo ndi mankhwala ena (onani gawo "Kuyanjana ndi mankhwala ena).

Zochitika zoterezi zimatha kuyambitsa kukula kwa hypoglycemia (komanso kutayika kwa magazi) wodwalayo asanadziwe kuti akupanga hypoglycemia.

Ngati ma glycosylated hemoglobin apezeka bwino, muyenera kuganiziranso kuti zingatheke kukhala ndi gawo la hypoglycemia lomwe limachitika mobwerezabwereza.

Kuchepetsa chiopsezo cha hypoglycemia, wodwalayo ayenera kutsatira mosamala mlingo woyenera ndi zakudya zopatsa thanzi, kupereka jakisoni wa insulin, ndikuwachenjezedwa za zizindikiro za kukhala ndi hypoglycemia.

Zinthu zomwe zimawonjezera kutsimikizira kwa chitukuko cha hypoglycemia zimafuna kuwunikira mosamala ndipo zingafune kusintha kwa mlingo.

Izi ndi monga:

Kusintha kwa dera la kayendetsedwe ka insulin,

Kuchuluka kwa insulin (mwachitsanzo kuchotsa zinthu zopsinjika),

Zosazolowereka (zowonjezera kapena zolimbitsa thupi nthawi yayitali),

Matenda amkati (kusanza, kutsegula m'mimba),

Zakudya zokwanira

Kudumpha chakudya

Matenda ena a insocrine osawerengeka (monga hypothyroidism ndi anterior pituitary insufficiency kapena adrenal cortex insuffence),

Kugwiritsa ntchito pamodzi mankhwala ena (onani gawo "Kuyanjana ndi mankhwala ena").

Pa matenda apawiri, kuyendetsa kagayidwe kolimba kumafunika. Nthawi zambiri, kuyesedwa kwa mkodzo kukhalapo kwa matupi a ketone kumasonyezedwa, ndikusintha kwa insulin nthawi zambiri ndikofunikira. Kufunika kwa insulin nthawi zambiri kumachuluka. Odwala omwe ali ndi matenda amtundu wa 1 ayenera kupitiliratu kudya pang'ono, ngakhale atangomaliza kudya pang'onopang'ono kapena ngati akusanza, ndipo sayenera kusiya kumwa mankhwala a insulin.

Zotsatira zamtanda

Mwa kuchuluka kwakukulu kwa odwala omwe ali ndi hypersensitivity kupita ku insulin ya nyama, ndizovuta kusinthira kwa insulin yaumunthu chifukwa cha mtanda wa immunological wa insulini ya anthu ndi insulin yochokera nyama. Ndi chidwi chowonjezeka cha wodwalayo kuti apange insulin yakuchokera kwa nyama, komanso m-cresol, kulekerera kwa mankhwala a Insuman® Rapid GT kuyenera kuwunikiridwa kuchipatala pogwiritsa ntchito mayeso a intradermal. Ngati pakuyesedwa kwa insulin ya insulin ya munthu kumadziwika, zotsatira zake, monga Arthus, ndiye kuti chithandizo china chikuyenera kuyang'aniridwa ndi achipatala.

Malangizo ogwiritsira ntchito cholembera cholembera cha SoloStar ® chodzaza

Asanayambe kugwiritsa ntchito, cholembera cha syringe chimasungidwa kutentha kwa firiji kwa maola 1-2.

Musanagwiritse ntchito, yang'anani cartridge mkati mwa cholembera. Iyenera kugwiritsidwa ntchito pokhapokha ngati njira ya insulini ili yowonekera, yopanda utoto, yopanda ma cell akunja.

Ma syringe a Emplo SoloStar ® sayenera kugwiritsidwanso ntchito ndipo ayenera kutayidwa.

Popewa matenda, cholembera chodzaza chisanachitike chizingogwiritsidwa ntchito ndi wodwala m'modzi ndipo sayenera kusamutsidwira wina.

Kugwira cholembera SoloStar ® Syringe

Musanagwiritse ntchito SoloStar ® Syringe pen, werengani mosamala zidziwitso zogwiritsira ntchito.

Chidziwitso chofunikira pakugwiritsa ntchito SoloStar® Syringe pen

Musanagwiritse ntchito, gwiritsani ntchito singano yatsopano ndi cholembera chonde ndikuyesani mosamala.

Ma singano okha omwe amagwirizana ndi SoloStar ® ndi omwe ayenera kugwiritsidwa ntchito.

Malangizo apadera amayenera kuchitika popewa ngozi zokhudzana ndi kugwiritsa ntchito singano komanso mwayi wopatsira matenda.

Musagwiritse ntchito cholembera cha SoloStar ® ngati chawonongeka kapena ngati mulibe chitsimikizo kuti chidzagwira ntchito moyenera.

Nthawi zonse khalani ndi cholembera cha syringe ya SoloStar ® ngati mungataye kapena kuwononga cholembera chanu cha SoloStar ®.

Malangizo osungira

Chonde werengani gawo la Kusungirako Zinthu kuti musunge malamulo a SoloStar® Syringe pen.

Ngati cholembera cha SoloStar ® chikusungidwa mufiriji, chotsani pamenepa patatsala maola awiri ndi theka jakisoni isanachitike kuti yankho lithe kutentha. Makamaka insulini yodziwika bwino imapweteka kwambiri.

Cholembera cha SoloStar ® Syringe chikuyenera kuwonongeka.

SoloStar® syringe cholembera iyenera kutetezedwa kufumbi ndi fumbi.

Kunja kwa SoloStar ® Syringe cholembera kumatha kutsukidwa ndikumupukuta ndi nsalu yonyowa.

Osamiza m'madzi, osadzitsuka kapena kupaka cholembera cha SoloStar ®, chifukwa izi zitha kuwononga.

SoloStar Syrrrr Syringe pen imapereka moyenera insulini ndipo ndi yoyenera kugwiritsa ntchito. Zimafunikanso kusamala mosamala. Pewani zochitika zomwe zowonongeka mu SoloStar® Syringe pen zingachitike. Ngati mukukayikira kuti cholembera cha SoloStar® Syringe mwina chawonongeka, gwiritsani ntchito cholembera chatsopano.

Gawo 1. Kuwongolera kwa insulin

Muyenera kuyang'anitsitsa cholembera pa SoloStar® Syringe pen kuti muwonetsetse kuti ili ndi insulin yolondola. Kwa Insuman® Rapid GT, cholembera cha SoloStar ® ndi choyera ndi batani lachikasu kuti mupeze jekeseni yothandizira. Pambuyo pochotsa kapu ya cholembera, mawonekedwe a insulini yomwe ili momwemo amawongolera: yankho la insulini liyenera kukhala lowonekera bwino, lopanda utoto, popanda mawonekedwe akunja akunja.

Gawo 2. Kulumikiza singano

Ma singano okhawo omwe amagwirizana ndi SoloStar® Syringe pen ayenera kugwiritsidwa ntchito.

Pa jakisoni wotsatira, gwiritsani ntchito singano yatsopano yosabala. Pambuyo pochotsa chipewa, singano iyenera kuyikiridwa mosamala pa cholembera.

Gawo 3. Kuchita mayeso a chitetezo

Pamaso pa jekeseni iliyonse, ndikofunikira kuyeserera chitetezo ndikuonetsetsa kuti cholembera ndi singano zimagwira bwino komanso thovu lakum air limachotsedwa.

Muyezo Mlingo wofanana magawo awiri.

Zovala za singano zakunja ndi zamkati ziyenera kuchotsedwa.

Ikani cholembera ndi singano kumtunda, ikani pang'onopang'ono katoni ya insulini ndi chala chanu kuti thovu lonse lakumwamba litayendetsedwe ku singano.

Kanikizani bwino batani la jakisoni.

Ngati insulini ikuwonekera pachimake pa singano, izi zikutanthauza kuti cholembera ndi singano zikugwira ntchito moyenera.

Ngati insulini siziwoneka pamphepete mwa singano, ndiye kuti gawo 3 limatha kubwerezedwanso mpaka insulini ikawonekera pamsonga pa singano.

Gawo 4. Kusankha Mafuta

Mlingo ukhoza kukhazikitsidwa ndi kulondola kwa 1 unit kuchokera pa mlingo wochepa wa 1 unit mpaka pazipita mlingo wa 80 mayunitsi. Ngati kuli koyenera kukhazikitsa mlingo wowonjezera wamagulu a 80, jakisoni wa 2 kapena kupitilira aperekedwe.

Zenera la dosing liyenera kuwonetsa "O" mukamaliza kuyesa chitetezo. Pambuyo pake, mlingo wofunikira ukhoza kukhazikitsidwa.

Gawo 5. Mlingo

Wodwala ayenera kudziwitsidwa za njira ya jakisoni ndi katswiri wazachipatala.

Singano iyenera kuyikiridwa pansi pa khungu.

Batani la jakisoni liyenera kukanikizidwa kwathunthu. Imachitika pamalo amenewa kwa masekondi 10 mpaka singano itachotsedwa. Izi zimathandizira kuyambitsa mtundu wa insulin kwathunthu.

Gawo 6. Kuchotsa ndi kutaya singano

Mulimonsemo, singano pambuyo pa jekeseni aliyense amayenera kuchotsedwa ndikuchotsedwa. Izi zimathandizira kupewa kuipitsidwa ndi / kapena kutenga kachilomboka, kulowa mu chidebe cha insulin ndi kutulutsa insulin.

Pochotsa ndi kutaya singano, muyenera kusamala mosamala. Tsatirani njira zoyenera zotetezera pochotsa ndi singano (mwachitsanzo, njira ya dzanja limodzi) kuti muchepetse ngozi za ngozi zogwirizana ndi singano komanso kupewa matenda.

Mukachotsa singano, tsekani cholembera cha SoloStar ® ndi chipewa.

Kukopa pa kuthekera kuyendetsa ma transp. Wed Ndi ubweya:

Mphamvu ya wodwalayo yokhazikika komanso kuthamanga kwa zochitika zama psychomotor zimatha kuwonongeka chifukwa cha hypoglycemia kapena hyperglycemia, komanso chifukwa chododometsa. Izi zimatha kukhala pachiwopsezo china chake munthawi yomwe maluso amafunikira (magalimoto oyendetsa kapena njira zina).

Odwala ayenera kulangizidwa kuti asamale komanso kupewa hypoglycemia poyendetsa. Izi ndizofunikira kwambiri kwa odwala omwe achepetsa kapena kusazindikira zizindikiro zomwe zikuwonetsa kukula kwa hypoglycemia, kapena okhala ndi zochitika zapafupipafupi za hypoglycemia. Mwa odwalawa, funso loti akhoza kuwayendetsa ndi magalimoto kapena njira zina ayenera kusankha payekha.

Kutulutsa mawonekedwe / Mlingo: Njira yothetsera jakisoni, 100 ME / ml. Kulongedza:

5 ml ya mankhwalawa mu botolo la galasi looneka komanso lopanda utoto (mtundu 1). Botolo limapangidwa m'maso, limafinya ndi chipewa cha aluminium ndikutchinga ndi kapu ya pulasitiki yoteteza. Mbale 5 yokhala ndi malangizo ogwiritsira ntchito pabokosi lamakatoni.

3 ml ya mankhwalawa mu katoni yamagalasi oyera ndi opanda khungu (mtundu I). Katirijiyo amakhazikika mbali imodzi ndi nkhata ndipo imamizidwa ndi kapu ya aluminiyamu, mbali inayo - ndi phula. Makatoni asanu pazinthu zilizonse za filimu ya PVC ndi zojambulazo. Mzere umodzi wa blister pamodzi ndi malangizo ogwiritsira ntchito pabokosi la makatoni.

3 ml ya mankhwalawa mu katoni yamagalasi oyera ndi opanda khungu (mtundu I). Katirijiyo amakhazikika mbali imodzi ndi nkhata ndipo imamizidwa ndi kapu ya aluminiyamu, mbali inayo - ndi phula. Makatoni amaikamo cholembera cha SoloStar®.

Pa 5 SoloStar sy syringe pensulo limodzi ndi malangizo ogwiritsira ntchito pakatoni.

Sungani pamalo amdima pa kutentha kwa 2 mpaka 8 ° C. Osamawuma.

Pewani kufikira ana.

Osagwiritsa ntchito tsiku lotha ntchito likusonyezedwa pa phukusi.

Zoyenera kufalitsa kuchokera ku malo ogulitsa ma fakitoreji: Pakulembedwera Nambala yalembetsa: P N011995 / 01 Tsiku lolembetsa: 03.03.2011 Mwini Malembeti Olembetsa: Sanofi-Aventis Deutschland GmbH Wopanga: & nbsp Kuimira: & nbsp Sanofi AventisGrupp AO Tsiku losintha:

Insuman Rapid GT ili ndi insulin yofanana ndi insulin yaumunthu ndipo yoyambitsidwa ndi mainjiniya ogwiritsa ntchito mtundu wa K12 kufinya E. Coli.

Zolemba zogwiritsira ntchito

Ngati vuto la glycemic likulephera kapena ngati matendawa ali ndi vuto la hyper- kapena hypoglycemia, musanaganize zosintha muyezo wa insulin, onetsetsani kuti mwalamulira insulin, onetsetsani kuti insulini idalowa mu malo omwe akutsimikiziridwa, yang'anani kulondola kwa njira ya jakisoni ndi zina zonse zomwe zingakhudze zotsatira za insulin. Popeza munthawi yomweyo makonzedwe angapo a mankhwalawa (onanigawo "Kulumikizana ndi mankhwala ena" kumatha kufooketsa kapena kukulitsa mphamvu ya hypoglycemic ya mankhwala a Insuman® Rapid GT, ndipo mukamagwiritsa ntchito, simuyenera kumwa mankhwala ena alionse popanda chilolezo chadokotala.

Hypoglycemia. Hypoglycemia imachitika ngati mlingo wa insulin uposa kufunika kwake. Chiwopsezo cha kukhala ndi hypoglycemia ndi chachikulu pamayambiriro a chithandizo cha insulin, mukasinthira kukonzekera kwina kwa insulin, mwa odwala omwe ali ndi shuga yayitali m'magazi. Monga ndi ma insulin onse, chisamaliro chapadera chiyenera kutengedwa ndikuwunika kwambiri kuchuluka kwa shuga m'magazi omwe odwala hypoglycemic episode angakhale ndi vuto lapadera la matenda, monga odwala omwe ali ndi vuto lalikulu la mitsempha kapena matenda a mitsempha (chiwopsezo cha mtima kapena matenda a m'magazi a hypoglycemia), akulimbikitsidwa. , komanso odwala omwe ali ndi proliferative retinopathy, makamaka ngati sanachite nawo mankhwala opatsirana pogwiritsa ntchito mankhwala a laser, popeza ali ndi chiopsezo chocheperako amaurosis (kwathunthu khungu) ndi chitukuko cha hypoglycemia.

Pali zizindikiro ndi zodwala zina zomwe ziyenera kuwonetsa kwa wodwala kapena ena za kukhala ndi hypoglycemia. Izi zimaphatikizapo thukuta lomwe limakulirakulira, chinyezi pakhungu, tachycardia, kusokonezeka kwa mtima, kuchuluka kwa magazi, kupweteka pachifuwa, kunjenjemera, nkhawa, njala, kugona, kusokonezeka kwa tulo, mantha, kukhumudwa, kusazolowereka, zosadziwika bwino, nkhawa, paresthesia mkamwa ndi kuzungulira pakamwa, kutsekeka kwa khungu, kupweteka mutu, kusokonekera kwa kayendedwe ka kayendedwe, komanso kuchepa kwa minyewa yamitsempha yamagazi (kufooka kwa mawu ndi masomphenya, zizindikiro zakuwala) ndi zomveka zachilendo. Ndi kuchepa kwakukulu kwa ndende ya glucose, wodwalayo amatha kulephera kudziletsa ngakhalenso kuzindikira. Zikatero, kuzizira ndi chinyezi pakhungu kumatha kuonedwa, ndipo kupweteka kumawonekeranso. Chifukwa chake, wodwala aliyense yemwe ali ndi matenda a shuga omwe amalandila insulin ayenera kuphunzira kuzindikira zizindikiro zomwe ndi chizindikiro cha kukhala ndi hypoglycemia. Odwala omwe nthawi zonse amayang'anira kuchuluka kwa shuga m'magazi samatha kukhala ndi hypoglycemia. Wodwala yekha amatha kukonza kuchepa kwa kuchuluka kwa shuga m'magazi omwe adazindikira mwa kudya shuga kapena chakudya chokhala ndi Malangizo apamwamba ogwiritsira ntchito: m chakudya. Pazifukwa izi, wodwalayo ayenera kukhala ndi 20 g shuga nthawi zonse. Mokulira kwambiri kwa hypoglycemia, jakisoni wokhazikika wa glucagon akuwonetsedwa (omwe angathe kuchitidwa ndi dokotala kapena antchito oyamwitsa). Pambuyo pakusintha kokwanira, wodwalayo ayenera kudya. Ngati hypoglycemia singathetsedwe mwachangu, ndiye kuti dokotala akuyenera kuyitanidwa mwachangu. Ndikofunikira kudziwitsa dokotala mwachangu za kukula kwa hypoglycemia kuti apange chisankho pakufunika kusintha kwa insulin. Kulephera kutsatira zakudya, kudumphira jakisoni wa insulin, kuchuluka kwa insulini chifukwa cha matenda opatsirana kapena matenda ena, komanso kuchepa kwa zochitika zolimbitsa thupi kungapangitse kuwonjezeka kwa ndende yamagazi (hyperglycemia), mwina ndi kuchuluka kwa matupi a ketone m'magazi (ketoacidosis). Ketoacidosis imatha kumatha maola ochepa kapena masiku. Pazizindikiro zoyambirira za metabolic acidosis (ludzu, kukodza pafupipafupi, kulephera kudya, kutopa, khungu lowuma, kupuma kwambiri komanso kuthamanga, chidwi cha acetone ndi glucose mkodzo), chithandizo chamankhwala chofunikira ndichofunikira.

Pakusintha dokotala (mwachitsanzo, nthawi yakuchipatala chifukwa cha ngozi, kudwala panthawi ya tchuthi), wodwalayo ayenera kudziwitsa dokotala kuti ali ndi matenda ashuga.Odwala ayenera kuchenjezedwa za machitidwe omwe zizindikiro zakuchenjeza za chitukuko cha hypoglycemia zingasinthe, osatchulika kapena kusapezeka kwathunthu, mwachitsanzo: ndi kusintha kwakukulu kwa kayendetsedwe ka glycemic, ndi kukula kwapang'onopang'ono kwa hypoglycemia, odwala okalamba, odwala omwe ali ndi vuto la neuronomic, mbiri yayitali ya matenda ashuga, odwala omwe amalandila chithandizo nthawi yomweyo ndimankhwala ena (onani gawo "Kuyanjana ndi mankhwala ena s). Zochitika zoterezi zimatha kuyambitsa kukula kwa hypoglycemia (komanso kutayika kwa magazi) wodwalayo asanadziwe kuti akupanga hypoglycemia. Ngati ma glycosylated hemoglobin apezeka bwino, muyenera kuganiziranso kuti zingatheke kukhala ndi gawo la hypoglycemia lomwe limachitika mobwerezabwereza.

Kuchepetsa chiopsezo cha hypoglycemia, wodwalayo ayenera kutsatira mosamala mlingo woyenera ndi zakudya zopatsa thanzi, kupereka jakisoni wa insulin, ndikuwachenjezedwa za zizindikiro za kukhala ndi hypoglycemia. Zinthu zomwe zimawonjezera kutsimikizira kwa chitukuko cha hypoglycemia zimafuna kuwunikira mosamala ndipo zingafune kusintha kwa mlingo. Zina mwazinthuzi ndi monga: kusintha kwa gawo la kayendetsedwe ka insulini, kuwonjezeka kwa chidwi cha insulin (mwachitsanzo, kuchotsa kwa nkhawa), zachilendo (kuchuluka kapena kuchita zinthu zolimbitsa thupi nthawi yayitali), matenda amtundu wamkati (kusanza, kutsegula m'mimba), chakudya chosakwanira, kudya chakudya, kumwa mowa, Matenda ena a uncocrensated endocrine (monga hypothyroidism ndi kusakwanira kwa anterior pituitary kapena adrenal cortex insuffence), kugwiritsa ntchito mankhwala ena (onani gawo "Kuyanjana ndi mankhwala ena"). Matenda apakati Pano okhala ndi matenda oyenda limodzi, mphamvu ya metabolic yofunika imafunikira. Nthawi zambiri, kuyesedwa kwa mkodzo kukhalapo kwa matupi a ketone kumasonyezedwa, ndikusintha kwa insulin nthawi zambiri ndikofunikira. Kufunika kwa insulin nthawi zambiri kumachuluka. Odwala omwe ali ndi matenda amtundu wa 1 ayenera kupitiliratu kudya pang'ono, ngakhale atangomaliza kudya pang'onopang'ono kapena ngati akusanza, ndipo sayenera kusiya kumwa mankhwala a insulin.

Zotsatira zamtanda. Mwa kuchuluka kwakukulu kwa odwala omwe ali ndi hypersensitivity kupita ku insulin ya nyama, ndizovuta kusinthira kwa insulin yaumunthu chifukwa cha mtanda wa immunological wa insulini ya anthu ndi insulin yochokera nyama. Ndi chidwi chowonjezeka cha wodwalayo kuti apange insulin yakuchokera kwa nyama, komanso m-cresol, kulekerera kwa mankhwala a Insuman® Rapid GT kuyenera kuwunikiridwa kuchipatala pogwiritsa ntchito mayeso a intradermal. Ngati pakuyesedwa kwa insulin ya insulin ya munthu kumadziwika, zotsatira zake, monga Arthus, ndiye kuti chithandizo china chikuyenera kuyang'aniridwa ndi achipatala.

Kukopa pa kuyendetsa magalimoto kapena njila zina. Mphamvu ya wodwalayo yokhazikika komanso kuthamanga kwa zochitika zama psychomotor zimatha kuwonongeka chifukwa cha hypoglycemia kapena hyperglycemia, komanso chifukwa chododometsa. Izi zimatha kukhala pachiwopsezo china chake munthawi yomwe maluso amafunikira (magalimoto oyendetsa kapena njira zina). Odwala ayenera kulangizidwa kuti asamale komanso kupewa hypoglycemia poyendetsa.Izi ndizofunikira kwambiri kwa odwala omwe achepetsa kapena kusazindikira zizindikiro zomwe zikuwonetsa kukula kwa hypoglycemia, kapena okhala ndi zochitika zapafupipafupi za hypoglycemia. Mwa odwalawa, funso loti akhoza kuwayendetsa ndi magalimoto kapena njira zina ayenera kusankha payekha.

Kuchita ndi mankhwala ena

Kugwiritsira ntchito mosiyanasiyana ndi othandizira pakamwa a hypoglycemic, angiotensin kutembenuza ma enzyme inhibitors, disopyramide, fibrate, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, propoxyphene, salicylates, amphetamine, anabolic steroids ndi abambo phenylphosphamphometrate, hemclophosphinometrate, hemclophosphometormin, hemocorhlometromu, hosphorphormines. , somatostatin ndi mawonekedwe ake, sulfonamides, tetracyclines, tritocqualin kapena trophosphamide Hypoglycemic zotsatira za insulin ndikuwonjezera kutengera kwa chitukuko cha hypoglycemia.

The ntchito kuphatikiza a corticotropin, corticosteroids, danazol, diazoxide, okodzetsa, glucagon, isoniazid, estrogens ndi progestogens (monga kupezeka mu kulera zosiyanasiyanazi kuphatikiza), opangidwa kuchokera phenothiazine, kukula timadzi, mankhwala sympathomimetic (mwachitsanzo, wa epinephrine, salbutamol, terbutaline), chithokomiro timadzi, barbiturates, nicotinic acid, phenolphthalein, phenytoin zotumphukira, doxazosin akhoza kufooketsa hypoglycemic zotsatira za insulin. Beta-blockers, clonidine, mchere wa lithiamu ukhoza kukhala wowonjezera kapena kufooketsa mphamvu ya hypoglycemic ya insulin.

Ethanol imatha kukhala yothandiza kapena kufooketsa mphamvu ya insulin. Kudya kwa Ethanol kumatha kuyambitsa hypoglycemia kapena kuchepetsa malangizo ochepa otsika: Magazi a glucose mpaka oopsa. Kulekerera kwa Ethanol mwa odwala omwe amalandira insulin kumachepetsedwa. Mitundu yovomerezeka ya zakumwa ziyenera kutsimikiziridwa ndi dokotala. Ndi makonzedwe munthawi yomweyo, kukulitsa kwa hypoglycemia ndikotheka, komwe nthawi zina kumatha kukhala hyperglycemia. Akaphatikizidwa ndi othandizira achifundo, monga beta-blockers, clonidine, guanethidine ndi reserpine, kufooka kapena kusapezeka kwathunthu kwa zizindikiro za Reflex (poyankha hypoglycemia) kutsegulira kwamanjenje kwamanjenje kumatha.