Momwe mungayang'anire cholesterol yamagazi?
Wolemba nawo nkhaniyi ndi Chris M. Matsko, MD. Dr. Matsko ndi dotolo wakale wochokera ku Pennsylvania. Anamaliza maphunziro ake ku Temple University Medical School mu 2007.
Chiwerengero cha magwero omwe agwiritsidwa ntchito m'nkhaniyi ndi 23. Udzapeza mndandanda wa iwo patsamba lomaliza.
Cholesterol ndi mafuta m'mwazi. Kuchuluka kwa kachulukidwe kolesterol (LDL) ndi kowopsa thanzi, chifukwa izi zimatha kuyambitsa mitsempha yolumikizidwa, yomwe imapangitsa ngozi ya mtima. Anthu ambiri amatha kuchepetsa cholesterol yamagazi mosavuta posintha pang'ono pazakudya ndi moyo wawo. Ngati mukuyesetsa kuti muchepetse cholesterol yanu, koma osaphula kanthu, ndiye kuti mungafune mankhwala apadera monga ma statins.
Cholesterol Meters
Mutha kuyeza cholesterol kunyumba kwathu. Muyenera kutsatira malamulo angapo, kunyalanyaza zomwe zimayambitsa kupotoza zotsatira.
Ndikulimbikitsidwa pasadakhale kuti muyambe kudya bwino, pewani zakudya zamafuta ndi chakudya. Pazaka zophunzirazi, kupatula zakumwa kapena khofi wina uliwonse.
Kuyeza kwa cholesterol sikuchitika osapitirira miyezi 3 atachitidwa opareshoni. Ma sampuli am'magazi amatengedwa pamalo oyimirira a thupi, choyamba muyenera kugwedeza dzanja lanu pang'ono.
Pafupifupi theka la ola musanaperekedwe, ndibwino kuti mukhale bata, kupatula masewera olimbitsa thupi. Munthu wodwala matenda ashuga akayesedwa ndipo pakufunika kuti akhazikitse kuchuluka kwa shuga, chakudya cham'mawa chimaletsedwa tsiku latha. Chakudya chamadzulo pasanathe maola 12 phunziro lisanachitike.
Kuyang'ana cholesterol kumachitika pogwiritsa ntchito chipangizo chapadera chonyamula, mizere yoyesera imaphatikizidwa mu zida. Pamaso kuwunikira komwe kumawongoleredwa, akuwonetsedwa kuti ayang'ane kulondola kwa zida zogwiritsira ntchito mwapadera.
Njira yoyeserera magazi ndi yosavuta:
- kuboola chala
- pukuta dontho loyamba la magazi
- gawo lotsatira limakodwa pa mzere,
- Mzere umayikidwa mu chipangizocho.
Pambuyo masekondi angapo, zotsatira za kafukufuku zimawonekera pazowonetsera chipangizocho.
Zida zoyesa zimagwira pamayeso a mayeso a litmus, amasintha mtundu kutengera kuchuluka kwa magazi ngati magazi. Kuti mupeze zambiri zolondola, simungathe kugwira mzerewo mpaka kumapeto kwa njirayi.
Zingwe zoyeserera zimasungidwa mumadzi osindikizidwa mwamphamvu kwa miyezi 6-12.
Momwe mungasankhire chida
Mukamasankha chida chowongolera cholesterol, muyenera kulabadira mfundo zingapo zofunika. Choyamba, amayang'ana mawonekedwe a chipangizocho komanso mawonekedwe ogwiritsira ntchito. Zimachitika kuti wofufuzayo amapatsidwanso njira zingapo zowonjezera zomwe wodwala samasowa nthawi zonse. Zosankha zotere zimakhudza mtengo wa chipangizocho. Zosafunikira kwenikweni ndi vuto lazodziwitsa, kukula kwa chiwonetsero.
Malangizo omwe ali ndi miyezo nthawi zonse amakhala olumikizidwa ku chipangizocho, omwe amatsogozedwa ndikamayang'ana zotsatira za kusanthula. Makhalidwe ololedwa amatha kusiyanasiyana kutengera matenda omwe wodwala matenda ashuga ali nawo. Pazifukwa izi, kufunsira kwa dokotala ndikofunikira, adzakuwuzani zomwe zikuwoneka ngati zabwinobwino, zomwe ndizazitali kwambiri komanso zosavomerezeka.
Ganizirani kupezeka kwa mizere yoyesa yogulitsa komanso kupezeka kwa iwo ali kit. Popanda iwo, kufufuza sikungathandize. Nthawi zina, mafuta a cholesterol amathandizidwa ndi chip chapadera, chimathandizira njirayi. Kitayo iyenera kukhala ndi chipangizo poboola pakhungu, imagwiritsidwa ntchito pochepetsa kusasangalala.
Mitundu ina imakhala ndi ntchito yosamalira zotsatira za muyeso; zimathandiza kusanthula mphamvu za mulingo wamafuta.
Zipangizo zodziwika bwino zowunikira cholesterol yamagazi zimatengedwa ngati zida:
- Accutrend (AccutrendPlus),
- Kukhudza kosavuta (EasyTouch),
- Multicarea (Multicare-in).
Kukhudza Kosavuta ndi glucose wamagazi ndi mita ya cholesterol yomwe imabwera ndi mitundu itatu yamizere yoyesera. Chipangizocho chimatha kusungira kukumbukira zotsatira za kafukufuku waposachedwa.
Multikea imakupatsani mwayi wodziwa kuchuluka kwa triglycerides, shuga ndi cholesterol. Pamodzi ndi chipangizocho, chipi cha pulasitiki chimaphatikizidwa, zida zokuboola khungu.
Accutrend idalandira ndemanga zabwino chifukwa chakutha kudziwa kuchuluka kwa lactates, cholesterol ndi shuga m'magazi. Chifukwa cha mlandu wapamwamba kwambiri womwe umachotsedwa, umalumikizana ndi kompyuta, imasungira kukumbukira zoposa zana zana zaposachedwa.
Njira zoyendetsera cholesterol
Njira yoperekera matenda a cholesterol ndi yayitali, imafunikira njira yophatikizira. Ndikofunikira kuchepetsa zisonyezo za zinthu zotsika kwambiri, komanso kusunga cholesterol yayitali kwambiri pamlingo wovomerezeka.
Pali njira zingapo zoyendetsera lipids: kudya, kusintha kwa moyo, mankhwala. Ngati njira zomwe zili pamwambazi sizikugwira ntchito, dokotala amasankha ngati opaleshoni ndiyofunikira. Pakati pa opaleshoni, zotsatira za atherosulinosis zimachotsedwa, magazi abwinobwino m'mitsempha amabwezeretsedwa.
Mosasamala kanthu chomwe chimayambitsa cholesterol yayikulu, chithandizo chimayamba ndikuwunika zakudya. Amathandizanso kuteteza matenda a metabolic, komanso amachepetsa kulowetsa mafuta akunja a nyama.
Kupanga cholesterol kukhala yabwinobwino, mafuta ochulukirapo a nyama ndi ochepa, ochuluka amapezeka mu malonda:
- nkhuku yolk
- tchizi okhwima
- wowawasa zonona
- kukhululuka,
- zonona.
Ndikofunika kukana chakudya kuchokera ku mafakitale, makamaka ngati agwiritsidwa ntchito kwakanthawi kogulitsa. Izi zimaphatikizapo mafuta a trans, mafuta ophikira ndi margarine.
Mafuta a cholesterol amachepetsa ngati mutadya zipatso zambiri, masamba. CHIKWANGWANI ndi pectin zilimo mwa izo zimapangitsa kuti kugaya kugaya, kugwetse mafuta m'thupi. Zothandiza pakuwongolera cholesterol zimaphatikizapo oatmeal, chinangwa, buledi wa tirigu wathunthu, pasitala wopangidwa ndi tirigu wa durum.
Ndikulimbikitsidwa kuti mukulitse kuchuluka kwamafuta osapanga omega-3, omega-6. Zokwanira zokwanira zilipo mtedza, nsomba zam'nyanja, zopendekera ndi mafuta a maolivi.
Masana, wodwala wokhala ndi cholesterol yambiri amaloledwa kudya magalamu 200 a lipids.
Kusintha kwamoyo
Ndi matenda a shuga ndi atherosclerosis yamitsempha yamagazi, muyenera kudziwa momwe mungayang'anire cholesterol. Kuchulukitsa kagayidwe kumathandizira kutsatira mfundo zachikhalidwe zabwino.
Zochita zolimbitsa thupi pafupipafupi zimawonetsedwa, kuchuluka kwa katunduyo kuyenera kusankhidwa payekhapayekha. Potere, m'badwo wa wodwalayo, kuuma kwa matendawa, kupezeka kwa mitundu ina yoyipa imakhudzidwa nthawi zonse.
Ndizabwino kuchita nawo masewera ngati awa:
Ngati wodwala sakhala wathanzi, amakhala ndi vuto la mtima, ndikofunikira kukulitsa katundu pang'onopang'ono.
Choyipa chofunikira kwambiri ndicho kumwa mowa mwauchidakwa ndi ndudu, khofi wamphamvu. Pothana ndi chizolowezi, kuchuluka kwa zinthu zoopsa m'thupi kumachepetsedwa, zomwe zimathandizira kubwezeretsa mafuta kagayidwe. Caffeine imalowetsedwa ndi tiyi wa zitsamba, chicory kapena hibiscus.
Ndikofunika kuti muchepetse kunenepa, makamaka ngati cholozera cha misa chochulukirapo kuposa mfundo 29. Kutaya kulemera kwanu 5 peresenti yokha, kuchuluka kwa cholesterol yoyipa kudzathanso.
Malangizo ndi abwino kwa odwala omwe ali ndi vuto la kunenepa kwambiri, pomwe chiuno cha mwamuna chimaposa 100 cm, kwa mkazi - kuchokera 88 cm.
Njira zachipatala
Zakudya ndi masewera olimbitsa thupi sizithandiza kubweretsa cholesterol, muyenera kuyamba kumwa mankhwala. Cholesterol imachepetsedwa chifukwa chogwiritsa ntchito ma statins, ma fibrate, othandizira a bile acids.
Ndemanga zabwino zalandira ma statins Rosuvastatin, Atorvastatin, Simvastatin. Mankhwalawa amasokoneza kupanga endo native cholesterol ndi chiwindi, ndikuwongolera kuyika kwake m'magazi. Imwani mankhwala ayenera kukhala miyezi 3-6 iliyonse.
Mitundu yodziwika bwino kwambiri ndi Fenofibrate, Clofibrate. Iwo ali ndi udindo wolimbikitsa kusintha kwa cholesterol mu bile acid. Zinthu zowonjezera zimachotsedwa m'thupi.
Okhazikika amamanga ma asidi a bile ndi cholesterol, ndikuwatulutsa kuchoka m'thupi. Njira zotchuka zinali Colestipol, Cholestyramine. Mapiritsiwo ali ndi omega-3s ndikuwonjezera cholesterol yamagazi okwera kwambiri. Othandizira a Hypolipidemic amathandizira kuchepetsa mwayi wowonjezereka wa arteriosulinosis.
M'malo mwake, kuwongolera cholesterol ndi ntchito yolumikizana kwa adokotala komanso odwala. Wodwala amafunika kupita kukafufuza zamankhwala pafupipafupi, kutsatira chakudya, kusanthula momwe mafuta amathandizira.
Ngati mfundo za cholesterol zomwe mukufuna zitheke, chiwopsezo cha kugwidwa ndi matenda a mtima chichepa katatu.
Kutanthauzira kwa Zotsatira
Malinga ndi kafukufuku waposachedwa, kuchuluka kwathunthu kwamafuta ngati magazi sayenera kupitilira 4.5 mmol / L. Koma panthawi imodzimodzi, ziyenera kukumbukiridwa kuti mawonekedwe enieni a cholesterol a mibadwo yosiyanasiyana amasiyana.
Mwachitsanzo, ali ndi zaka 45, cholesterol imadziwika kuti ndi yachilendo pamlingo wa 5.2 mmol /,, munthu akamakula, ndiye kuti chizolowezi chimakula. Kuphatikiza apo, kwa amuna ndi akazi, Zizindikiro zimasiyana.
Zochitika zawonetsa kuti sikofunikira kupita ku labotale nthawi yonse kuti muwongolere cholesterol. Ngati muli ndi gluroeterical glucometer yabwino komanso yolondola, wodwala matenda ashuga angadziwe zamadzimadzi zamagazi osachoka panyumba panu.
Zipangizo zamakono zofufuzira mwachangu zakhala gawo latsopano la zamankhwala .Mitundu yaposachedwa ya owunikira imapangitsa kuti asamangowona kuchuluka kwa shuga ndi cholesterol, komanso kuchuluka kwa triglycerides.
About atherosclerosis ndi cholesterol akufotokozedwa mu kanema munkhaniyi.
Momwe mungachepetse cholesterol ngati yatalika kale?
Dokotala wanu akazindikira kuti kuchuluka kwa cholesterol yamagazi anu kumakwezedwa panthawi ya cheke (kapena ayi), palibe chomwe chatsala koma kuti muphunzire kuilamulira.
Dokotala ndiye gwero labwino koposa la upangiri ndi upangiri pankhaniyi. Tsatirani upangiri wake kuti mupewe zovuta, makamaka ngati mukuvutika ndi kunenepa kwambiri, matenda ashuga, kapena kudalira fodya. Zonsezi ndizowonjezera zowopsa za cholesterol yayikulu.
Pali magawo asanu osavuta owongolera cholesterol yanu. Koma palibe chifukwa choti musawatsatire kuti awononge mankhwala omwe dokotala wakupatsani. Izi ndi zina mwazinthu zomwe mungathe kubwerera mwachizolowezi.
Musaiwale za masewera olimbitsa thupi
Musaiwale kuchita masewera olimbitsa thupi pafupipafupi - tsiku lililonse kwa theka la ola.
Izi ndi zabwino kwambiri paumoyo ndipo, pazinthu zina, zimachepetsa cholesterol "yoyipa" ndikuwonjezera kuchuluka kwa "zabwino" ndi pafupifupi 10%.
Sikoyenera kuchita masewera olimbitsa thupi ndikuwononga nthawi yolimbitsa thupi. Kuyenda theka la ola ndi njira yabwino yowunikira thanzi lanu (ndi chithunzi).
Kodi cholesterol ndi bwenzi kapena mdani?
Kodi ndikofunikira bwanji kuyang'anira cholesterol m'thupi? Malinga ndi kafukufuku wa US National Institute for the Study of Cardiovascular Disease, matendawa ndi omwe amachititsa mpaka 60% ya matenda onse amtima wapadziko lapansi. Kuphatikiza apo, zochitika zoyika pangozi monga kugunda kwa mtima komanso matenda opha ziwopsezo, mu 40% ya milandu ndi chifukwa cha cholesterol yayikulu.
Chifukwa chake, cholesterol (OX) ndichilengedwe chophatikiza chomwe chimapangidwa mu kapangidwe ka mankhwala kwa lipophilic alcohols. Izi zimatha kulowa m'matumbo ndi chakudya, kapena kupangika m'maselo a chiwindi. Cholesterol ndiyofunika kuti ikhale ndi moyo wabwinobwino, chifukwa imagwira ntchito zingapo zofunika mthupi:
- Ndi gawo limodzi la nembanemba ya cytoplasmic - maselo oyang'anira maselo. Mamolekyulu amowa amachititsa kuti khoma la cell likhale lolimba komanso lopanda, ndikuwongolera kupezekanso kwake.
- Ndi gawo limodzi lamahomoni a steroid omwe amapezeka m'magazi a adrenal glucocorticoids, mineralocorticoids, androgens ndi estrogens.
- Amatenga nawo kapangidwe ka bile acids ndi vitamini D wolemba hepatocytes.
Cholesterol imanyamula zinthu zonse zakubadwa ngati zili m'magazi mkati mwazinthu zoyambira 3.2-5.2 mmol / L. Kuwonjezeka kwakukulu kwa phula ili m'magazi ndi chizindikiro chodziwika bwino cha kuchepa kwa lipid m'thupi.
Kuphatikiza pa kuchuluka kwazakumwa zakumwa zoledzeretsa, kuchuluka kwa dyslipoproteinemia (kuphwanya ubale wamthupi pakati pamagawo osiyanasiyana a OH) kumathandizanso kukulitsa kwa atherosulinosis. Amadziwika kuti cholesterol yathunthu imagawidwa kukhala:
- VLDLP - tinthu tambiri timene timakhala ndi mafuta komanso triglycerides,
- LDL - kachigawo ka cholesterol chomwe chimanyamula ma cell mamolekyulu kuchokera ku chiwindi kupita ku maselo a thupi, gawo la lipid pakupanga kwake ndilokulirapo kuposa mapuloteni,
- HDL - tinthu tating'onoting'ono tokhala ndi gawo lalikulu la mapuloteni komanso mafuta ochepa. Cholesterol imatengedwa kupita ku maselo a chiwindi kuti ikapitirize kukonzanso mu bile acid ndi kutaya zina.
VLDL ndi LDL nthawi zambiri amatchedwa cholesterol "yoyipa". Mukamayenda pabedi lamankhwala, tinthu timeneti timatha "kutaya" gawo la mamolekyulu amafuta, omwe pambuyo pake amakhazikika pamakoma am'mitsempha, amakhala osalimba ndikukula. Njira imeneyi imayambitsa kupangidwa kwa zolembedwa za atherosulinotic.
HDL, pomwepa, ilibe ma molekyulu ambiri opanda mafuta ndipo, ikafika pafupi ndi bedi lamitsempha, imatha kugwira tizilomboto “totayika”. Chifukwa chakutha kuyeretsa makoma a malo atherosulinotic, HDL imatchedwa cholesterol "yabwino".
Kukula kwa atherosulinosis kumakhazikitsidwa pakusavomerezeka pakati pa "yoyipa" ndi "wabwino" cholesterol. Ngati zomwe zili zoyambirira zikhala zochulukirapo kuposa 2-2.5, ndiye kuti chiopsezo chokhala ndi vuto la metabolic wodwalayo chikuwonjezeka. Ndiye chifukwa chake anthu onse azaka zopitilira 25-30 amalimbikitsidwa kuyang'ana zomwe zili mu cholesterol mzaka zonse za 3-5, ngakhale zitakhala kuti sizikuvuta.
Tengani kafukufuku
Kuyesedwa kwa magazi kwa cholesterol ndi njira yodziwika yodziwira matenda a metabolic, omwe amachitika mu labotale iliyonse. Aliyense akhoza kuzidutsa.
Kuphatikiza apo, pali zisonyezo zina zachipatala zoyesedwa:
- IHD, angina pectoris,
- ochepa matenda oopsa
- matenda atherosclerosis,
- discirculatory encephalopathy,
- shuga ndi matenda ena a metabolic,
- xanthomas a nkhope ndi thupi - mawonekedwe osakhazikika, makamaka okhala ndi cholesterol,
- matenda a chiwindi - hepatitis, matenda enaake,
- Matenda ogwirizana ndi kusokonekera kwa mahomoni ogonana,
- cholowa dyslipidemia.
Odwala omwe ali ndi matenda ofotokozedwa pamwambapa amafunika kuwongolera cholesterol ndi zigawo zake 1-4 pachaka.
Osuta nawonso amagwera m'gulu langozi - madokotala amalimbikitsa kuti apezeke ndi vuto la mafuta metabolism miyezi isanu ndi umodzi iliyonse.
Njira zazikulu zothandizira ma labotale kuchuluka kwa cholesterol ndikuwunika kwa OX ndi mtundu wake wowonjezera - mbiri ya lipid. Zomwe zimayesedwa ndi magazi ndi a venous kapena capillary (kuchokera pachala).
Kuti zotsatira za kafukufukuyu zikhale zodalirika momwe zingathere, ndikofunikira kukonzekera pasadakhale:
- Kusanthula kumachitika pang'onopang'ono pamimba yopanda kanthu: chakudya chotsiriza chiyenera kukhala usiku usanathe maola 12. M'mawa wa tsiku lodana ndi magazi, mumangomwa madzi okha.
- Masiku atatu musanapendeketsedwe, tikulimbikitsidwa kupatula zakudya zamafuta ndi zokazinga, kukana maphwando okondwerera, osatinso kudya.
- Osamwa mowa kwa masiku awiri 2-3 musanayesedwe.
- Mwakugwirizana ndi adokotala nthawi yomweyo, kupatula (ngati zingatheke) kugwiritsa ntchito mankhwala ndi zowonjezera zakudya. Ngati mankhwalawo akufuna kuti mugwiritse ntchito mosalekeza, dziwitsani dokotala wanu, komanso othandizira omwe azakuwunikirani za mankhwalawo.
- Musasute osachepera mphindi 30-45 musanatengere magazi.
- Pewani kupsinjika ndi kuchita masewera olimbitsa thupi kwambiri musanayesedwe.
Kudziwa cholesterol sikutanthauza njira zovuta zowonera: nthawi zambiri mayesowa amakhala okonzekera maola ochepa. Mmanja mwa wodwalayo mwapatsidwa kalata yolembera yolozera kutanthauza (zabwinobwino) zomwe amagwiritsa ntchito m'gululi, ndipo zotsatira zake. Kuti muwunikire za kayendedwe kazinthu zamafuta a kagayidwe kake ndi kagwiritsidwe ntchito kake, sungani zotsatira zonse zoyesedwa.
Othandizira kusanthula ndi maimidwe oyesera kuti adziwe cholesterol kunyumba akukhala otchuka kwambiri. Ngakhale pali zopindulitsa zambiri (kugwiritsa ntchito mosavuta, kupeza zotsatira pambuyo pa mphindi 2-3, mtengo wotsika kwambiri), kudalirika kwa zida zotere kumatsika poyerekeza ndi zida zapadera zomwe zimagwiritsidwa ntchito mu labotale.
Ngati mulingo wa OH ndi wabwinobwino ndipo mukumva bwino, palibe chifukwa chodera nkhawa. Bwerezani mayeso pambuyo pazaka 3-5 kapena ngati pali zovuta zaumoyo.
Kukula kwa kuchuluka kwa mafuta m'thupi m'mwazi, komanso "skew" pazigawo za zigawo za lipid, kumafunikira kukaonana ndi dokotala. Ngati ndi kotheka, katswiriyu adzalembanso mayeso ena ndikulemba njira yothandizira ena. Amawongolera odwala omwe ali ndi atherosulinosis ndi dyslipidemia, komanso amawongolera cholesterol mtsogolomo ndi katswiri wamkulu (wamtima).
Njira zoyendetsera cholesterol yanu
Matenda a metabolism yamafuta ndi njira yayitali ndipo nthawi zonse imafunikira njira yophatikizira. Ndikofunikira kuti muchepetse kuchuluka kwa cholesterol m'mwazi, komanso kuisunga pamlingo womwe mukufunako pamoyo wanu wonse. Ndikotheka kuwongolera magazi a OX pamagwiritsidwe:
- Njira zosagwiritsa ntchito mankhwala osokoneza bongo - kudya, kukonza njira, kukana zizolowezi zoipa,
- mankhwala - mankhwala ochokera ku gulu la pharmacological lama statins, ma fibrate, othandizira a bile acids, etc.,
- Njira zochitira opaleshoni zomwe cholinga chake ndikuchepetsa mavuto a atherosulinosis ndi kubwezeretsa kufalikira kwamatumbo.
Zakudya ndi gawo lofunika la chithandizo
Kugwiritsa ntchito zakudya, odwala atherosulinosis sangangokulitsa kagayidwe kazakudya, komanso amachepetsa kwambiri kudya mafuta achilengedwe.
Kuti muchepetse cholesterol yanu, tsatirani malangizo awa:
- Chepetsa zakudya zamafuta a nyama zambirimbiri ndi chakudya, zomwe zimakhala ndi mafuta ambiri (nyama ya nkhumba, ng'ombe) ndi offal, kirimu, batala, tchizi yakucha ndi mazira a nkhuku.
- Kanani kudya zakudya zopukutidwa kwambiri zomwe zimakhala ndi mafuta ambiri (margarine, salomas, mafuta ophikira).
- Idyani zamasamba ambiri ndi zipatso: pectin yomwe ilimoyo samangokulitsa kugaya, komanso amachepetsa cholesterol.
- CHIKWANGWANI kumawonjezera zomwe zili "zabwino" lipids mthupi. Yesani kuphatikiza chinangwa, oatmeal, mkate wa c / s kapena pasitala muzakudya zanu.
- Onjezani kuchuluka kwamafuta osakwanira omwe ali ndi thupi lanu (omega-3) muzakudya zanu. Mochulukitsa, ali mbali ya nsomba zam'nyanja zamafuta, mtedza, maolivi ndi mafuta ophatikizika.
- Imwani madzi ambiri abwino.
Zofunika! Masana, odwala atherosulinosis amalangizidwa kuti asamadye cholesterol yoposa 200 mg.
Kodi moyo wa wodwala wodwala atherosulinosis uyenera kukhala wotani?
Ndi atherosclerosis, monga matenda ena aliwonse, amafunika kutsatira mfundo za moyo wathanzi.
"Imathandizira" kagayidwe kake ndikuchepetsa kuchuluka kwa lipids zoyipa mthupi kumathandiza:
- Kuchita masewera olimbitsa thupi pafupipafupi. Mlingo wa kupsinjika uyenera kusankhidwa ndi dokotala aliyense payekha malinga ndi zaka, thanzi la wodwalayo, kupezeka kwa matenda othandizira, etc. Kusambira, kuvina, yoga, kuyenda, kutsatira, ma pilate amatengedwa ngati masewera oyenera pakuwongolera dyslipidemia. Ndi kusakonzekera bwino kwa wodwala kapena kupezeka kwa mtima wamagazi, katundu pa thupi amakula pang'onopang'ono.
- Kukana zizolowezi zoipa. Kusuta fodya komanso kumwa mowa mwauchidakwa ndi zina mwazomwe zimayambitsa kukulitsa cholesterol. Mukamaliza kuthana ndi vuto losokoneza bongo, kudya zinthu zapoizoni m'thupi kumachepa, zomwe zimathandiza kubwezeretsanso mafuta.
- Kuchepetsa thupi (kokha kwa odwala omwe BMI yawo imaposa 29). Kuchepetsa thupi ngakhale 5% ya kulemera kwanu kumakupatsani mwayi wochepetsera kuchuluka kwa lipids "zoyipa" m'magazi. Izi ndizowona makamaka kwa anthu omwe amatchedwa kuchepa thupi kwa visceral, momwe m'chiuno chimadutsa 100 cm mwa amuna ndi 88 cm mwa akazi.
Mapale motsutsana ndi cholesterol: machitidwe a ntchito ndi mawonekedwe ogwiritsira ntchito
Ndikofunika kudziwa kuti si nthawi zonse ndi cholesterol okwera omwe adotolo amakupatsani mapiritsi. Nthawi zambiri, mayendedwe a mafuta kagayidwe kachakudya mu thupi amathanso kuonetsetsa mwa kuwongolera kadyedwe komanso kakhalidwe.
Kufunika kolumikizana mankhwala ochizira kumanenedwa ngati njira zosagwiritsa ntchito mankhwalawa sizothandiza kwa miyezi itatu kapena kupitilira. Mankhwala osankhidwa ndi monga:
- Statins - Atorvastatin, Rosuvastatin, Simvastatin. Pewani kupanga cholesterol amkati m'maselo a chiwindi, potero amawongolera zomwe zili m'magazi. Chovomerezedwa ndi maphunziro azitali a mankhwala (miyezi 3-6 kapena kupitirira).
- Fibates - Clofibrate, Fenofibrate. Yambitsani kusintha kwa cholesterol mu bile acids, amathandizira kuthetsa mafuta ochulukirapo m'thupi. Zitha kutumikiridwa molumikizana ndi ma statins.
- Otsatira a bile acid - Cholestyramine, Colestipol. Amamanga cholesterol ndi ma asidi a bile m'mimba, amaonetsetsa kuti akutuluka m'thupi.
- Omega-3 - zowonjezera zakudya zomwe zimapanga zakudya zomwe zimapangitsa kuti lipids "zabwino", zichotse kusokonekera kwa metabolic ndikuthandizira cholesterol yotsika.
Chithandizo cha lipid-kutsitsa wothandizidwa ndi dokotala amathandizira kuchepetsa chiopsezo cha zovuta za atherosulinosis.
Chifukwa chake, kuyang'anira kwa OX ndi zigawo za lipid ndi ntchito yolumikizana kwa adokotala komanso odwala. Kupimidwa pafupipafupi, kutsatira mfundo za kadyedwe ka hypocholesterol ndi moyo wathanzi, komanso kumwa mankhwalawa kungathandize kukwaniritsa zotsatira zabwino. Malinga ndi European Society of Cardiology, kukwaniritsa zofunika za cholesterol, LDL ndi HDL kumachepetsa chiopsezo cha kugunda kwamtima ndi stroko nthawi zopitilira katatu.
Pewani mafuta odzaza
Nthawi zonse timakumana ndi zakudya zamafuta. Zimakhala kuti mazira amawonjezera cholesterol yamagazi, koma, asayansi alibe chitsimikizo pa izi. Kafukufuku wambiri awonetsa kuti mafuta odzazidwa amawonjezera cholesterol.chifukwa chake yesetsani kupewa zakudya zamafuta. Zakudya zophika, othamanga, msuzi - zonsezi ndizovulaza thupi lanu.
Onjezani mtedza kuzakudya zanu
Kafukufuku wochitidwa ndi asayansi padziko lonse lapansi awonetsa izi kudya pafupipafupi mtedza uliwonse ndi zipatso zouma kumachepetsa magazi m'thupi. Musaiwale, komabe, izi ndizakudya zopatsa thanzi kwambiri, ndipo simuyenera kuzunza.
Siyani mowa ndi fodya
Mukamasuta, ndiye kuti zimavulaza kwambiri mapapu anu. Ngakhale siliri vuto lokhalo. Ndudu zimatsitsanso cholesterol "yabwino" m'magazi, zimathandizira pamlingo wa "zoyipa". Mowa nawonso umawononga thanzi lanu. Yesetsani kusiya zizolowezi zonsezi.
Monga mukuwonera, njira zisanu zowongolera cholesterol ndizosavuta. Izi ndi zizolowezi zabwino zomwe muyenera kukhala nazo kuti muwonetsetse thanzi lanu. Samangoyang'anira cholesterol, komanso amathandizanso kumva bwino tsiku lililonse.
Izi zimaletsa matenda osiyanasiyana. Kupewa matendawa, makamaka m'njira yosavuta chonchi, nthawi zonse kumakhala kwabwinopo komanso kosavuta kuposa kuchiza.
Momwe mungayang'anire cholesterol yamagazi?
Makina angapo a oxidative amatha kupangitsa kuti makutidwe a oxidation a LDL, kuphatikizapo NADPH oxidases, xanthine oxidase, myeloperoxidase, unbound nitide oxide synthase, lipo oxygenase, ndi mitochondrial elekitala yoyendera. Tizilombo ta Ox-LDL timawonetsa zinthu zambiri za atherogenic, zomwe zimaphatikizira mayamwidwe ndi kuchuluka kwa ma macrophages, komanso pro-yotupa, immunogenic, apoptotic ndi cytotoxic, kuyambitsa kwa mawonekedwe a mashesi am'madzi pama cell a endothelial, kukondoweza kwa kusiyanasiyana kwa ma monocyte ku macrophages ndi kutulutsa ndi ma cyrophages. kuchokera ku macrophages.
Makamaka, pamlingo wa endothelial, ROS imayang'anira njira zambiri zowonetsera, kuphatikiza owongolera kukula, kuchuluka, kutuluka kwa maselo a endothelial, chotchinga ndi ntchito yokonzanso mtima. Pomwe mulingo wa VSMC, kukula kwa ROS kumateteza kukula, kusunthidwa, malamulo a matrix, kutupa ndi mawonekedwe, zonsezi ndizofunikira kwambiri pakukula ndi kuphatikizika kwa atherosulinosis.
Kusintha kwazovuta pakati pa kuphatikiza kwa oxidative ndi atherosclerosis chifukwa cha kupsinjika kwa oxidative kumabweretsa kukula ndi kupitirira kwa atherosclerosis. Momwe mungayang'anire cholesterol? Kuwongolera kwa cholesterol ndiko kuyesa kosalekeza ndikukhalabe ndi moyo wabwino.
Zofunika! Mutha kuwongolera cholesterol ndi zakudya. Muyenera kupatula pachakudya chanu zakudya zonse zomwe zimakhala ndi cholesterol yambiri, komanso kuwongolera kuchuluka ndi kudya kawiri.
Oligoelements m'madzi amatha kutonga cholesterol
Kafukufuku wa Epidemiological awonetsa kuchuluka kwa anthu odwala matenda amtima komanso matenda amitsempha yamagazi m'magawo okhala ndi madzi ofewa komanso kulumikizana kopanda pakati pa kuuma kwamadzi ndi kufa kwamtima. M'malo mwake, palibe umboni wokwanira wosonyeza ngati madzi olimba ali ndi zinthu zoteteza zomwe sizikhala m'madzi ofewa, kapena ngati pali zinthu zovulaza m'madzi ofewa.
Madzi amakhala ndi ma oligominerals, monga:
Zomwe ndizofunikira pochepetsa chiopsezo cha CVD. Kumbali inayo, zinthu monga cadmium, lead, siliva, mercury ndi thallium zimawonedwa kuti ndizoyipa.
Kuperewera kwa magnesium kumawerengedwa kuti ndi vuto pachiwopsezo cha matenda amtima, makamaka, kuwonjezera kwake kumachedwetsa kuyambika kwa atherosclerosis kapena kumalepheretsa kukula. Kumbali inayo, silicon ndiye chinthu chachikulu chotsalira pazakudya za nyama, ndipo anthu amamwa 20 mpaka 50 mg / tsiku la silicon wokhala ndi zakudya zaku Western. Zomwe zimapatsa thanzi ndizopatsa tirigu ndi zakudya zake (kuphatikiza mowa), mpunga, zipatso ndi ndiwo zamasamba, ndi madzi akumwa, makamaka madzi am'madzi am'madzi okhala ndi botilo komanso mapiri ophulika. Kafukufuku wambiri awonetsa kuti silicon imathandizira kusunga umphumphu, kukhazikika ndi zotanuka kwa makoma ochepa ndipo yaikapo silicon ngati njira yoteteza pachitukuko cha matenda okhudzana ndi misempha monga atherosulinosis ndi matenda oopsa. Kuphatikiza apo, akukhulupirira kuti vanadium ili ndi anti-atherosulinotic katundu. Lithium itha kulepheretsanso kuphatikizika kwa cholesterol, koma imakhala ndi zochita za atherogenic, zomwe zitha kuletsedwa ndikuwonjezera calcium. Chakudya chosakwanira mkuwa chimatha kuyambitsa hypercholesterolemia ndi hypertriglyceridemia, yomwe imakulitsidwa ndi chakudya chama zinc.
Kutengera zowerengeka izi, kumwa kwa silicon, magnesium ndi vanadium m'madzi ndi kupewa kuwonetsa cadmium ndi lead ndizofunikira kwambiri popewa matenda amtima, chifukwa chake, madzi olimba ali ndi phindu pa thanzi ndipo sayenera kulowedwa ndi madzi akumwa osakwanira pazinthu zopindulitsa. Ndikofunikanso kukumbukira kuti madzi amathandizira pang'ono pazakudya zam'mimbazi poyerekeza ndi chakudya chokwanira (7% cha madzi motsutsana ndi 93% ya chakudya cholimba).
Zofunika! Anthu amayang'anira cholesterol mosalekeza, atatha zaka 60. Kuti muchite izi, ndibwino kugula mita yapadera ya cholesterol kunyumba. Kotero mutha kudziwa chizindikiritso cha cholesterol chanu ndikuchiwongolera.
Zowonjezera za Melatonin Zitha Kuthetsa Cholesterol
Melatonin, yemwe amapanga indolamine mochulukitsa, ndi molekyu yopindulitsa modabwitsa yomwe imagwira ntchito ngati antioxidant yogwira ntchito komanso yopanda ufulu wosasintha. Kuwongolera kuchuluka kwa cholesterol ndizowonjezera izi ndizosavuta. Kutulutsa mosatulutsa bwino komanso mochuluka kwa melatonin kumathandizira mu mtima.
Imatha kufalikira mwachangu mthupi lonse ndipo imatha kudutsa zopinga zonse za thupi ndi kulowa mosavuta m'magazi amtima komanso m'mitsempha. Kuchulukana kwambiri kwa melatonin kumawoneka kukhala mu mitochondria. Izi ndizofunikira kwambiri chifukwa mitochondria ndiye malo akuluakulu opangira ma free radicals komanso m'badwo wa oxidative nkhawa. Kuphatikiza apo, kugwiritsa ntchito melatonin pazinthu zosiyanasiyana, pakamwa komanso mkati, kwatsimikizira kukhala kotetezeka pamaphunziro a anthu.
Melatonin imawoneka kuti ili ndi zochita za atheroprotective mu makutidwe ndi okosijeni a LDL, ndi melatonin precursors ndi zinthu zowonongeka zimalepheretsa oxidation wa LDL wofanana ndi vitamini E. Chifukwa cha lipophilic yake komanso chikhalidwe chake chosagwirizana, melatonin iyenera kulowa gawo la lipid la tinthu ta LDL ndikuletsa peroxidation lipids, komanso imathandizanso kuti chilolezo cha amkati chidziwike.
Molunjika, melatonin imalepheretsa kupangika kwa ma cellular oxidative mwanjira inayake, ikulimbikitsa kupanga ma cell a antioxidant enzymes ROS, makamaka glutathione peroxidase, glutathione reductase ndi superoxide desmutase. Melatonin, kuwonjezera pa kukhala antioxidant wogwira mtima kuposa resveratrol, imatha kuyang'aniridwa kuwonongeka kwa DNA ya oxidant chifukwa cha kupsinjika kotsalira kwa resveratrol mukawonjezeredwa.
Kuphatikiza apo, 6-hydroxymelatonin, yofunika kwambiri mu vivo metabolite ya melatonin komanso kutsogola kwake N-acetyl-5-hydroxytryptamine, inali yothandiza kuchepetsa LDL peroxidation mu vitro. Kuthekera kwa molekyulu ya kholo ya melatonin, komanso ma metabolites ake, kugwira ntchito panthawi yopanga detoxization kumawonjezera mphamvu yake yoletsa kuzunza kwa oxidative pamisempha yambiri m'maselo.Chifukwa chake, titha kulingaliridwa kuti ngakhale melatonin imakhala ndi zotsatira zolimbitsa thupi kapena zamankhwala chifukwa chopewa vide oxidative oxidation wa LDL, machitidwe ake adzakhala ogwirizana kwambiri ndi catabolite yake yayikulu. Melatonin imatha kukhala yoteteza komanso yopindulitsa pa matenda amtima, kuchepetsa chiopsezo cha atherosulinosis ndi matenda oopsa.
Ndikofunikira kutsindika kuti kupezeka kwaposachedwa kwa melatonin mu mphesa kumatsegulira njira zatsopano mu gawo la njira zachilengedwe za antioxidant athero-chitetezo. Ndiosavuta kuyang'anira cholesterol pakudya moyenera.
Pomaliza
Chifukwa chakumvetsetsa kwakukulu za mawonekedwe ndi kupanga kwa ROS ndi oxidative nkhawa ndikuwonetsa kuyanjana mwachindunji kapena kosakhudzana ndi atherosclerosis, kuchepa kwa ROS kapena kuchepa kwa mitengo yawo yopanga kungachedwetse kuyambika ndi kupitilira kwa atherosclerosis. Ukalamba umathandizira pakusintha kwachilengedwe, monga kupsinjika kwa oxidative, kutupa ndi endothelial dysfunction, zomwe zimagwirizana kwambiri ndi pathophysiology ya atherosulinosis.
M'malo mwake, umboni wamphamvu ukusonyeza kuti kuwonjezera kudya zakudya zoyenera zomwe zimakhala ndi zopatsa thanzi komanso zopatsa thanzi m'magazi a antioxidant zitha kuthandizira kusintha moyo mwachangu pakuchepetsa komanso kuchepetsa ngozi ya matenda amtima ndipo, makamaka, kupanga njira zodziwikiratu zomwe zimagwira ntchito kupanikizika kwa oxidative, komwe kumatenga pathogenesis ya atherosulinosis komanso ndi zovuta pang'ono kapena zovuta zoyipa, kungapereke kufanana kofanana ndi achire Chithandizo cha atherosulinosis. M'malo mwake, njira zothandizira mtima wodwala prophylaxis ndi chithandizo ayenera kuganizira njira yosavuta, yachindunji, komanso yotsika mtengo monga njira yoyamba yakulemerera kwa matenda amtima, okha kapena kuphatikiza mankhwalawa. Munkhani iyi, chidwi chachikulu chaperekedwa kwa vinyo, tiyi, zipatso ndi mafuta a maolivi, chifukwa ali olemera kwambiri mu antioxidants achilengedwe.
Komabe, kumvetsetsa bwino njira zopatsira kufalitsa ma siginolo kutengera kupanikizika kwa oxidative, kukhazikitsa kwawo ndikusakanikirana ngati njira yodalira ROS ndikuwonetsa njira mu mtima pathophysiology kungakhale njira iliyonse yofunikira pakuwongolera kwa zamankhwala komanso kopanda mankhwala kuti mtima utetezedwe pamavuto a oxidative.
Pomaliza, lingaliro lakuti antioxidants lingachedwetse kupita patsogolo kwa atherosulinosis ndi yosangalatsa komanso yolimbikitsa, koma kufufuza kwina ndikofunikira kumvetsetsa bwino zomwe zimatsindika zazotsatira zamoyo wathanzi. Sungani cholesterol yanu ndipo mukhale athanzi.
Ngati cholesterol yotsika, kodi imawopseza bwanji thanzi la anthu? Ndi cholesterol yotsika, matenda osiyanasiyana ambiri amatha kuonekera.
Kodi ndichofunika kuti muchepetse cholesterol
Koma kodi ndikofunikira kuti muchepetse cholesterol yayikulu ndi mankhwala? Kapena kodi pali mankhwala achilengedwe kuti muchepetse? Komabe, musanalengeze nkhondo ya cholesterol, muyenera kuonetsetsa kuti miyesoyo imamveka komanso kuchuluka kwa cholesterol, kwenikweni, imaposa zomwe zimachitika.
Yankho la funso ngati ili limangopereka chithandizo chamankhwala chapadera. Ndikwabwino kunyalanyaza njira zina, popeza mu 80% ya milandu, kuchuluka kwa cholesterol kumatsimikiziridwa ndi cholakwika chachikulu mosavomerezeka.
Mpaka pano, chikhalidwe cha cholesterol ndi 5.2 mmol / L. Komabe, ngakhale chizindikiritso chake chikukwera pang'ono, mwachitsanzo, 6 mmol / l, palibe chifukwa chodandaulira, chifukwa palibe choopsa chomwe chidzachitike m'thupi.
Koma ngati kupsinjika kwake kudapitilira mulingo wa 7-7.5 mmol / l, ndiye, ndiye nthawi yakumveketsa. Ponena za chizindikiro cha cholesterol monga 10 mmol / L, muyenera kufunafuna chithandizo chamankhwala, popeza ndizosatheka kale kuthana ndi vuto lanu.
Ndikofunikanso kumvetsetsa kuti kupewa matenda okhudzana ndi mtima sikumangokhudza kulimbana ndi cholesterol. Kafukufuku waposachedwa ndi asayansi akuwonetsa kuti kuchepa kwa kugwiritsidwa ntchito ndi 15-30% sikumapereka chitetezo chowonjezera kwa minofu yamtima. Akatswiri ambiri amakhulupirira kuti cholesterol yokha siyowopsa, chifukwa thupi limafunikira kuti izigwira ntchito bwino.
Cholesterol "Chabwino" ndichomwe chimapangira maselo a ma cell, chimatenga nawo gawo pakupanga kwa mahomoni ndipo ntchito ya ubongo ndiosatheka popanda iwo. Kolesteroli "yoyipa" yokha ndiyomwe imavulaza anthu, yomwe imasinthika pamakoma amitsempha yama mitsempha ndi mitsempha, ndikutseka kwa nthawi. Apa mpofunika kumenya naye nkhondo.
Zakudya za cholesterol
Tiyenera kudziwa kuti njira yothandiza kwambiri yolimbana ndi cholesterol "yoyipa" ndiye chakudya choyenera. Ndikothekanso kuwongolera cholesterol potsatira malangizo ena okhudzana ndi zakudya. Mwachitsanzo, ngati muchepetsani kudya zakudya zopezeka m'mapuloteni a nyama. Zimamvekanso bwino kuti muchepetse kuchuluka kwa zakudya zopezeka ndi cholesterol yambiri "yoyipa" muzakudya zanu zomwe zimaphatikizapo:
- wowawasa zonona, mkaka wopindika, mafuta amtundu wa tchizi wolimba, kefir ndi mkaka,
- mbatata zokazinga, makamaka zophika,
- kanjedza, mafuta a kokonati ndi margarine,
- nyama yamafuta, masoseji, mafuta,
- makeke, makeke, makeke ena,
- Msuzi wowawasa ndi mayonesi
- mafuta anyama ndi batala,
- msuzi wamafuta
- mazira.
Kuchepa kwa gawo la zinthu izi muzakudya kumabweretsa kuchepa kwakukulu kwa ndende ya cholesterol. Mwa kumveketsa, ndikungoyala batala ndi masamba, kumakuthandizani kuti muzitha kuchepa kwa mafuta a cholesterol kuyambira 12 mpaka 15%.
Ngati tizingolankhula za zinthu zomwe zimathandizira kuti cholesterol yotsika, ndiye kuti zakudya zaku Mediterranean zitha kuonedwa ngati zabwino pankhaniyi. Dongosolo loterolo la zakudya limaphatikizapo kuphatikizidwa muzakudya za tsiku ndi tsiku zamasamba ambiri ndi zipatso, zakudya zam'nyanja ndi nsomba, mtedza, zipatso zouma ndi mafuta.
Kukhala koyenera kupindulitsa zakudya zanu ndi zophatika zamafuta:
Zomera zoterezi zimatenga bwino mafuta m'thupi ndipo zimachotsa thupi.
Garlic ndi tiyi wobiriwira ndizothandiza kwambiri. Chifukwa chake, zinthu zotere zimachepetsa kugwira ntchito kwa ma enzymes omwe amayambitsa kuthana ndi mafuta kuchokera ku chakudya, ndipo chifukwa chake amasiya thupi la munthu lisasinthike. Ponena za adyo, izi, kuphatikiza kutha kuthana ndi kuchuluka kwa mafuta m'thupi, zimakhala ndi kuthekera kwapadera kosungunuka magazi, ndimathanso kutsitsa shuga m'magazi ndikulimbitsa chitetezo cha mthupi.
Musaiwale za flaxseed, chifukwa imakhala ndi zitsulo, zinthu zomwe zimathandizira kuyendetsa mafuta m'thupi. Kuti mupeze zotsatira zabwino, muyenera kugwiritsa ntchito 2000 mg ya sterols tsiku lililonse, lofanana ndendende ndi 2 tbsp. l mafuta a mbewu ya fulakesi. Kuphatikiza apo, kudya kwa nthawi yayitali kwa spirulina ndi alfalfa kumathandizanso kutsika kwa cholesterol.
Komabe, munthu sayenera kukhala ndi chiyembekezo chachikulu chowonjezera ndi kuphatikizika kwake. Zonsezi zimatsitsa cholesterol pokhapokha zimagwiritsidwa ntchito kuchuluka kwa 30 g, ndipo pazowonjezera zimakhalapo pang'ono. Komabe, ngakhale michere yama microscopic imeneyi imapatsidwa mwayi woletsa kupanga mapangidwe a cholesterol pamakoma amitsempha yamagazi.
Njira zina zolimbana ndi cholesterol
Koma kudya zakudya zoyenera si njira yokhayo yolembera cholesterol. Ambiri amadziwa bwino kuti ndi gawo lokwera la chinthu ichi, muyenera kuyang'anira thupi lanu. Munjira zambiri, njirayi imatengera chakudya, koma zolimbitsa thupi ndizofunikira. Komanso, zikuchitika kuti kusewera masewera samangotsitsa cholesterol "yoyipa", komanso pa 10% kumakulitsa "zabwino".
Kuti izi zitheke, ndikokwanira kugwiritsa ntchito mphindi 30 zokha patsiku pochita masewera olimbitsa thupi. Ngakhale munthu wosachita masewera olimbitsa thupi amatha kulowa mkati mwa ola lathunthu nthawi zonse, ndipo zotsatira zake zidzakhala chimodzimodzi. Koma si zokhazo. Kukana zizolowezi zoipa kudzakhalanso kofunikira.
Chowonadi ndi chakuti kusuta sikuvulaza mapapu, komanso kumachepetsa cholesterol "yabwino" ndipo izi zimangowonjezera kuchuluka kwa "zoyipa". Mowa ulinso ndi katundu yemweyo. Ndiye chifukwa chake ndikofunikira kusiya zosokoneza izi posachedwa. Njira zochepetsera cholesterol sizovuta kwambiri, ndipo zimangothandiza kulimbana ndi cholesterol yoyipa, komanso zimakuthandizani kuti muzimva bwino.