Chingalowe m'malo mwa Fraxiparin: ma analogues ndi ma fanizo a mankhwalawa

Muzochita zachipatala, madokotala a akatswiri ambiri (a hematologists, ma psychetologists, maopaleshoni) nthawi zina amakumana ndi zochitika zachipatala zomwe zimafunikira kuti azidziwitsidwa ndi hepatatic system ya thupi. Kwa nthawi yayitali, madokotala akhala akugwiritsa ntchito mankhwala omwe amatha kusintha magwiridwe antchito a magazi. Popita nthawi, mankhwalawa akukhala ochulukirachulukira, mtundu wawo, wogwira ntchito ndipo, chofunikira, chitetezo chawo chikuchulukirachulukira. Masiku ano, imodzi mwa mankhwala othandizira kwambiri ndi Clexane, komabe, pali zochitika zingapo pomwe cholinga chake sichingatheke.

Ngati wodwalayo sakugwirizana ndi mankhwalawo pazifukwa zina, ma fanizo osankhidwa ayenera kusankhidwa ndi katswiri wodziwa ntchito yake. Mutha kusintha nokha mankhwalawo, chifukwa izi zitha kuyambitsa mavuto ena azaumoyo.

Zambiri zamankhwala

Ndi mankhwala omwe ali ndi anticoagulant mwachindunji. Kuphatikizidwa kwa mankhwala ofotokozedwawo kumaphatikizapo sodium ya Enoxaparin, yomwe imagwira ntchito monga chinthu chachikulu chomwe chimagwiritsa ntchito njira zonse zochizira mthupi. Mlingo womwe ukupezeka kuchokera pa 20 mpaka 100 mamililita. Yofunika ndende amasankhidwa kuganizira za matenda ndi labotale magawo a wodwala aliyense.

Makina ochitapo kanthu amatengera kuthekera koletsa zinthu zina zophatikizika (chachiwiri, chachisanu ndi chiwiri ndi chachikhumi). Chifukwa chake, mankhwalawa amatha kusokoneza kupangika kwa kapangidwe ka magazi ndi thrombus. Kuletsa kwa zinthu pamwambapa kumachitika chifukwa cha kutsegula kwa antithrombin 3, yomwe ili m'magazi.

Mankhwalawa amapezeka mwanjira yokonzekera-yoyendetsera, yoyikidwa mu ma syringe ena apadera a subcutaneous makonzedwe. Kutulutsidwa kwamtunduwu kumathandizira kwambiri kugwiritsa ntchito mankhwalawa ndipo kumawalola odwala kuti azilankhula okha, popeza amaphunzira kale ndi akatswiri azachipatala.

Izi mankhwala analamula zochizira pachimake thrombosis osiyanasiyana kutanthauzira. Komanso, kugwiritsidwa ntchito kumakhala koyenera ngati prophylaxis mwa odwala omwe ali pachiwopsezo cha zovuta zovuta za thrombotic.

Mwa zina, titha kusiyanitsa mankhwalawa omwe ali ndi mawonekedwe ofanana, koma opangidwa ndi makampani ena opanga mankhwala, ndi omwe ali ndi mawonekedwe osiyana, koma ali ndi vuto lofanana ndi Clexane m'thupi.

M'malo mwake kungakhale kofunikira ngati wodwalayo wawulula zizindikiro za kusalolera kwa mankhwalawo, mavuto aliwonse komanso zovuta zina. Komanso, kusankha analogue yotsika mtengo kumafunikira pomwe wodwala sangakwanitse kugula mankhwala omwe wapatsidwa.

Clexane kapena Fraxiparin: ndibwino

Fraxiparin ndi mankhwala oletsa kuperewera. Komabe, imakhala ndi calcium nadroparin, yomwe imanena za hepatin ochepa. Mankhwalawa amapezekanso mu ma syringe omwe ali ndi yankho lokonzekera kugwiritsa ntchito. Ubwino wosakayikira wa Fraxiparin ndi mtengo wake wotsika, zomwe zimapangitsa kuti zitheke kwa gulu lalikulu la odwala. Zisonyezero zoika mankhwala onse akuyerekeza machitidwe

Gemapaksan kapena Kleksan: zomwe mungasankhe

Mankhwala onse awiriwa ndi ofanana kwambiri, chifukwa amachokera paziphatikizidwe zomwezo (enoxaparin). Mndandanda wazomwe zikuwonetsa ndi zotsutsana pazomwe tafotokozazi ndizofanana. Gemapaxan ndi wotsika mtengo kwambiri, ngakhale atapangidwa kunja (Italy). Palibe data yodalirika yomwe mankhwalawa ndi othandiza komanso otetezeka. Madokotala omwe nthawi zambiri amagwira ntchito ndi mankhwalawa amatsutsa kuti zotsatira zake ndizofanana. Mavuto amapezeka pafupipafupi mu mankhwala oyamba ndi achiwiri.

Makhalidwe oyerekeza Pradaxa ndi Kleksan

Kuphatikizidwa kwa Pradaxa kumaphatikiza yogwira dabigatran etexilate, yomwe ili m'gulu la otsutsana mwachindunji ndi thrombin. Pradaxa imalowa m'thupi la munthu osagwira ntchito. Pambuyo mayamwidwe kuchokera m'mimba mundawo mu kufalikira kwazinthu, imayikidwa mu hepatocytes chifukwa cha michere ya enzymatic ndi mankhwala okhala momwemo.

Chifukwa chake, odwala omwe adayikidwa Pradax sayenera kukhala ndi chiwindi chokwanira, chifukwa izi zimapangitsa chiwindi kuwonongeka.

Zofunika! Ubwino wa Pradaxa ndi kuthekera kwa kayendetsedwe kosasokoneza (komwe kamapezeka mufomu ya piritsi).

Heparin kapena Clexane: ndibwino

Zomwe zimagwira mu Clexane zimachokera ku Heparin. Chifukwa chake, Heparin amawoneka kuti ndi wolemera kwambiri wopanga maselo, ndipo Clexane ndi wolemera pang'ono wovuta. Fomula ya Clexane idatengedwa pambuyo pake, motero mankhwalawa ndi otetezeka komanso othandizira, komanso sangathenso kutsogolera kukula kosafunikira.

Tiyenera kukumbukira kuti chiopsezo chokhala ndi zovuta zotere kuchokera ku heparin, monga autoimmune thrombocytopenia, chimapitiliza kupereka mankhwala olemera ochepera.

Zibor monga analog

Pulogalamu yogwira ya Zibor ndi mchere wa sodium wa ochepa maselo wolemera heparin (sodium bemiparin). Mankhwalawa amagwiritsidwa ntchito kwambiri pochita opaleshoni komanso mu nephrology (amalembedwa kwa odwala omwe akuchitidwa ndi extracorporeal hemodialysis pa zida zopangira impso). Ma kachitidwe ka Zibor akufanana kwathunthu, chifukwa mankhwalawa amalepheretsa thrombosis chifukwa chasokonezeka ndikuyenda kosagwirizana. Zibor silingagwiritsidwe ntchito muubwana chifukwa chakuti sipanakhalepo maphunziro okwanira pazokhudza mankhwalawa pa thupi la ana.

Enixum ndi Clexane: kuyerekezera kwa mankhwala

Kuphatikizidwa kwa mankhwalawa kumaphatikizanso mankhwala omwewo, omwe amawerengetsa kufanana kwa mankhwalawa. Enixum komanso Clexane amapezeka mu mtundu wa jekeseni wofunitsitsa makina oyendetsa. Mankhwalawa akupezeka pamiyeso isanu ndi itatu, zomwe zingathandize adotolo kusankha njira yabwino komanso yotetezeka yankho la wodwalayo.

Nthawi zambiri, Enixum amadziwika kuti ndi prophylaxis kwa odwala a zipatala zochita opaleshoni omwe amachitidwa opaleshoni yayikulu (makamaka ma opaleshoni yamankhwala a musculoskeletal system).

Enoxaparin sodium monga analogue wa Clexane

Kapangidwe ka mankhwalawa onse ndi ofanana, chifukwa chake, zikuwonetsa zonse ndi zosakanikira pazomwe amagwiritsa ntchito ndizofanana. Onse a Enoxaparin sodium ndi Clexane amayendetsedwa ndi jekeseni wa subcutaneous, yomwe si njira yosangalatsa kwa odwala ambiri.

Panthawi yomwe sizingatheke kupereka mankhwala mwachidziwitso, Enoxaparin sodium sangathe kusintha. Kafukufuku yemwe anganene molondola kuti ndi iti mwa mankhwalawa omwe ndi othandiza kwambiri omwe sanachitike, koma pochita bwino kwake ndi kofanana ndikufanana.

Zina zotsika mtengo

Clexane ndi mankhwala okwera mtengo kwambiri, makamaka mukaganiza kuti muyenera kumayambitsa maphunziro onse. Chotsatira, timapereka mndandanda wamankhwala omwe atha kusintha mankhwalawa, koma kukhala ndi mtengo wotsika:

Dzinalo Lopanda Padziko Lonse

Fericxina dzina lake Fraxiparin, lomwe limawonetsa kuphatikizika kwa mankhwalawa, ndi calcium ya Nadroparin, dzina ladziko Lachilatini ndi Nadroparinum calcium.

Mankhwala Fraksiparin 0,3 ml

Maina onse ogulitsa mankhwalawa, ophatikizidwa ndi dzina limodzi, amakhala ndi mphamvu zofanana pa thupi la munthu mikhalidwe komanso kulimba kwake.

Kuphatikiza pa dzinalo, kusiyana pakati pa mankhwala omwe amasiyana ndi omwe amapanga ali mu kipimo, komanso kapangidwe kazomwe zimapezeka ndi mankhwala osokoneza bongo komanso omwe amachokera ku mankhwala osagwirizana ndi mankhwala.

Wopanga

Mankhwala otchedwa Fraxiparin amapangidwa ku France kumalo opangira ma famu a gulu lalikulu kwambiri lachipatala ku Europe, GlaxoSmithKline, yemwe ofesi yake ku London.

Komabe, mankhwalawa ndiokwera mtengo kwambiri, kotero kuti makampani opanga mankhwala amapanga mawonekedwe ake ambiri.

Otsatsa otsika mtengo kwambiri amaphatikizapo:

• Nadroparin-Farmeks wopangidwa ndi Farmeks-Gulu (Ukraine),
• Novoparin wopangidwa ndi Genofarm Ltd (UK / China),
• Flenox yopangidwa ndi PAO Farmak (Ukraine),

Zogulitsa zotere zimapangidwanso ndi makampani angapo azamankhwala aku India ndi ku Europe. Malinga ndi zomwe zimachitika mthupi, ndizofanana.

Zotsatira za pharmacological

Calcium nadroparin ndi heparin yochepa kwambiri (NMH) yomwe imapezeka kuchokera ku heparin yokhazikika, ndi glycosaminoglycan yokhala ndi kulemera kwakukulu kwa 4300 daltons.

Ikuwonetsa kuthekera kwakukulu kumangiriza mapuloteni a plasma ndi antithrombin III (AT III). Kumangiriza kumeneku kumabweretsa kuyendetsa patsogolo kwambiri kwa factor Xa, komwe kumachitika chifukwa cha kuthekera kwakukulu kwa nadroparin.

Njira zina zopereka antithrombotic zotsatira za nadroparin zimaphatikizanso kutsegula kwa minyewa ya kusintha kwa inhibitor (TFPI), kutsegula kwa fibrinolysis pomasulidwa mwachindunji kwa minofu ya plasminogen activell maselo a endothelial, ndikusintha kwamitsempha yamagazi ndi kuchepa kwamphamvu kwa kupatsidwa magazi kuundana.

Calcium nadroparin imadziwika ndi ntchito yapamwamba ya anti-Xa chinthu poyerekeza ndi anti-IIa factor kapena antithrombotic zochita ndipo imakhala ndi zochita komanso zotheka nthawi yayitali.

Poyerekeza ndi heparin yopanda kukonzekera, nadroparin imakhala yocheperako pakugwira ntchito ya maplatelet ndi kuphatikiza, komanso samatchulidwa kwenikweni pa hemostasis yapamwamba.

Mu Mlingo wa prophylactic, nadroparin sayambitsa kuchepa kutchulidwa kwa APTT.

Ndi chithandizo cha mankhwala munthawi ya zochitika zapamwamba, kuwonjezeka kwa APTT pamtengo 1.4 nthawi zambiri kuposa momwe mungathere. Kutalika kotereku kumatsalira otsalira a antithrombotic mphamvu ya calcium nadroparin.

Pharmacokinetics

Facacokinetic katundu amatsimikiza pamaziko a kusintha kwa ntchito ya anti-Xa chinthu cha plasma.

Pambuyo pakuyang'anira kwa Cmax mu plasma kumatheka mu maola a 3-5, nadroparin imatengedwa pafupifupi kwathunthu (pafupifupi 88%). Ndi pa / pakukhazikitsa ntchito yotsutsa XA imatheka osakwana mphindi 10, T1 / 2 ili pafupifupi maola 2

Zimapangidwa makamaka mu chiwindi mwa kuwonongedwa ndi depolymerization.

Pambuyo pa utsogoleri wa SC T1 / 2 ili pafupifupi maola 3.5. Komabe, ntchito za anti-Xa zimapitilira kwa maola osachepera 18 pambuyo pobayira jekeseni wa nadroparin pa 1900 anti-XA ME.

Mlingo

Mankhwala amapezeka mu mawonekedwe a yankho la jakisoni. Kutengera ndi wopanga ndi mitundu, mitundu ingapo ya mankhwala atha kupezeka.

Ochulukirapo ndi miyeso ya mamilimita 0,2, 0,3, 0,6 ndi 0,8. Kampani yaku Germany Aspen Pharma ikhoza kuperekedwa mu mulingo wa mamilimita 0.4.

Kunja, yankho lake ndimadzimadzi wopanda mafuta wopanda khungu kapena wamtambo wachikasu.Mankhwala amakhalanso ndi fungo. Chizindikiro cha Fraxiparin ndichakuti yankho siliperekedwa muma ampoules omwe sitimawadziwa makasitomala athu, amafuna kuti kugula kwa syringe koyenera komanso koyenera kwa mankhwalawa kusanachitike.

Mankhwalawa amagulitsidwa jakisoni wapadera wa syringe, wokonzeka kugwiritsidwa ntchito. Kuti mupereke jakisoni, ndikokwanira kuchotsa kapu yodziteteza ku singano ndikulimbira pa piston.

Chofunikira chachikulu

Ma polysaccharide olekanitsidwa ndi chiwindi ndi ogwira anticoagulant.

Kamodzi m'magazi, heparin amayamba kumangiriza kumalo a cationic a tri-antithrombin.

Zotsatira zake, mamolekyulu a antithrombin amasintha katundu wawo ndikupanga ma enzyme ndi mapuloteni omwe amachititsa kuti magazi azigwirizana, makamaka pa thrombin, kallikrein, komanso serine proteinase.

Kuti chinthucho chigwire ntchito mwachangu komanso mwachangu, molekyu yake "yayitali" ya polymer imagawidwa pang'onopang'ono mwa depolymerization pansi pazinthu zapadera pazida zovuta.

Mimba analogues

Fraxiparin wa mankhwalawa amagwiritsidwa ntchito nthawi yapakati.

Zowonadi, nthawi imeneyi, chifukwa cha kusintha kwa ma mahomoni, mphamvu za magazi zomwe zimawonjezeka, zomwe zimatha kubweretsa mitolo yambiri. Ndi fanizo ziti za mankhwala zomwe ndizovomerezeka kumwa mwana wosabadwa?

Nthawi zambiri, Angioflux amagwiritsidwa ntchito - chisakanizo cha tizigawo tating'onoting'ono tomwe timatulutsa timene timatulutsidwa kuchokera ku mucosa. Makapisozi onse amkamwa komanso njira zowonjezera zothandizira jakisoni zilipo.

Analog ina yomwe imagwiritsidwa ntchito kwambiri pathupi ndi hepatrombin. Malinga ndi kapangidwe kazinthu zomwe zimagwira, ndimayendedwe mwamtheradi a Fraxiparin, komabe, imasiyana mu mawonekedwe. Mosiyana ndi izi, hepatrombin imapezeka mu mawonekedwe a mafuta ogwiritsira ntchito kunja.

Pomaliza, kukonzekera kwa Wessel Douay F, komwe kumakhala mitundu yosakanikirana ndi ma polysaccharides - glycosaminoglycans, kumathandizanso ku Fraxiparin. Kuwongolera kwawo kumathandizanso kugwirizanitsa kwa magazi X pazomwe zimayambitsa nthawi yomweyo ma prostaglandins komanso kuchepa kwa kuchuluka kwa fibrinogen m'magazi.

Zofananira zotsika mtengo

Tsoka ilo, monga zinthu zambiri zaku Europe, Fraxiparin ndiokwera mtengo kwambiri. Komabe, pali mitundu yake yotsika mtengo yomwe imaloleza kupewa koyenera ndi chithandizo cha mawonetseredwe a thrombotic ndikusunga ndalama. Zofanizira zotsika mtengo kwambiri za mankhwalawa ndi mankhwala opangidwa ku China, India ndi CIS.

Enoxaparin-Farmeks jakisoni njira

Kukula kopezekanso kumachitika ndi mankhwala omwe amadziwika kuti Eneksaparin-Farmeks aku Ukraine. Pokonzekera kampani "Farmeks-Gulu", chinthu chachikulu chomwe chimapangidwanso ndimothandizirana, ndiko kuti, chosagwirizana, heparin.

Osakwera mtengo kwambiri kuposa Enoxarin wopangidwa ndi Biovita Laboratories - gulu lalikulu la mankhwala ku India. Imalinso ndi syringe yapadera yotaya ndipo imakhala ndi chinthu chofananira - calcium yokhala ndi "ifupi "heparin.

Mmalo ofala kwambiri a Fraxiparin ndi mankhwala otchedwa Clexane. Mankhwala achifalansa agwiritsidwa ntchito popanga, zomwe zimatsimikizira kuti mankhwalawa ndi otetezeka kwambiri.

Kusiyana kwa Fraksiparin kuchokera ku Kleksan

Clexane amasiyanitsidwa ndi mtengo wokwera, koma ndi iye yemwe amamuwona ngati madotolo angapo ochita masewera olimbitsa thupi kuti akhale othandizira komanso othandiza kwambiri pa nthawi yapakati.

Kugwiritsa ntchito bwino kwa Clexane kumakhalapo kwa nthawi yayitali, kuphatikizana ndi Fraxiparin, zimakhudza thupi.

Clexane Jekeseni

Malinga ndi machitidwe wamba, ndikofunikira kuyendetsa Fraxiparin kawiri pa tsiku. Nthawi yomweyo, Clexane amathandizira mkati mwa maola 24, omwe amachepetsa kuchuluka kwa jakisoni ndi theka.

Popeza kuti mankhwalawa amatengedwa kwa nthawi yayitali, kuchepa kwa chiwerengero cha jekeseni tsiku ndi tsiku kumakondedwa malinga ndi chilimbikitso cha odwala komanso thanzi.

Kupanda kutero, mankhwalawa ali ofanana ndendende ndipo samasiyana mwanjira yotulutsidwa, kapena pazinthu zomwe zimagwira, kapena momwe thupi limayang'anira.

Fraxiparin kapena Heparin

Komabe, pakadali pano ikulowedwa m'malo ndi Fraxiparin ndi ma analogues ake.

Malingaliro oti Heparin amawoloka chotchinga ndipo akhoza kukhala ndi vuto pa mwana wosabadwa ndi wopanda nzeru.

Malinga ndi kafukufuku, onse a Fraxiparin ndi Heparin samawonetsa kuthekera kolowera placenta ndipo akhoza kukhala ndi vuto pa mwana wosabadwayo pokhapokha mlingo wovomerezeka udapitilira.

Kupezeka kwa Fraxiparin muzochitika zamankhwala zamakono kumafotokozedwa kokha ndi kupezeka kwa kugwiritsa ntchito kwake - apo ayi mankhwalawo ali ndi zofanana zofanana.

Fraxiparin kapena Fragmin

Fragmin, monga mankhwala ena mgululi, ali ndi heparin. Komabe, Fragmin amagwiritsidwa ntchito ngati coagulant, mosiyana ndi Fraxiparin, wopangidwa kuti agwiritse ntchito panthawi yapakati.

Fragmin jakisoni

Ngati chomaliza chili ndi calcium calcium yogwiritsira ntchito, ndiye kuti Fragmin amakhala ndi mchere wa sodium wa heparin. Pali umboni kuti pankhaniyi, Fragmin imakhudzanso thupi.

Mukamamwa mankhwalawa, magazi ochokera m'mitsempha yochepa thupi amakhala ochulukirapo. Makamaka, kugwiritsa ntchito Fragmin kumatha kuyambitsa mphuno zapakhungu, komanso kutaya magazi kwa mtima.

Makanema okhudzana nawo

Momwe mungapangire jekeseni wa Clexane:

Pafupifupi pali mitundu pafupifupi khumi ndi iwiri ya Fraxiparin, yomwe imasiyana mtengo wokwera kapena kuchitapo kanthu kwa nthawi yayitali, ndikukulolani kuti mupulumutse ndalama popewa kugwedezeka kwamwazi wamagazi komwe kumachitika pakapita nthawi yokhala ndi vuto lakumimba kapena matenda a enzymatic.

• Imakhazikika pamisempha ya shuga kwa nthawi yayitali
• Imabwezeretsa kapangidwe ka insulin

Phunzirani zambiri. Osati mankhwala. ->

Isoprinosine® - analogues ndiotsika mtengo, mtengo wa Russian ndi zotengera zina

Othandizira komanso Osagulitsa A Isoprinosine Substitutes

Mu nthawi yophukira-nyengo yozizira, thupi la munthu limakhala langozi kwambiri pamavuto angapo a virus.

Pakadali pano, aliyense ayenera kukhala ndi mankhwala othandizira kunyumba. Imodzi mwa mankhwalawa ndi Isoprinosine®.

Mankhwalawa ndi othandizadi, koma si wodwala aliyense amene angakwaniritse mtengo wake mumafakisi. Chifukwa chake, ndikofunikira kulingalira kuti ndi mitengo yanji yotsika mtengo ya mankhwalawa yomwe ilipo.

Zotsatira zamankhwala

Isoprinosine ndi chogwiritsa ntchito chogwiritsa ntchito chothandizira. Muli 4-acetamidobenzoic acid ndi inosine.

Gawo loyamba limasintha gawo la magazi ndi zinthu zake zofunika kudzera mwa nembanemba. Chifukwa cha izo, ntchito ya ma lymphocyte imakulirakulira, ndipo mafotokozedwe a ma membrane receptors amalimbikitsidwa. Maselo a Lymphocyte amachepetsa ntchito chifukwa kuwonekera kwa glucocorticoids, ndipo mumaphatikizanso thymidine mwa iwo.

Gawo lachiwiri limalimbikitsa ntchito ya cytotoxic lymphocyte, limalepheretsa mapangidwe otupa a cytokines.

Inosine amakana ma virus a herpes simplex, chikuku, fuluwenza A, B. Chowoneka chachikulu ndi chithandizo cha matenda a herpes.

Munthawi ya makonzedwe a mankhwalawa, pamakhala machiritso amathandizidwe am'malo mwachangu kuposa zina, njira zamankhwala.

Kupezeka kobwereranso mwa mawonekedwe a matuza atsopano, njira zakukokoloka ndi edema ndizokayikitsa. Pankhaniyi, kuyambitsidwa kwakanthawi kwa mankhwalawa ndikofunikira, komwe kumachepetsa zovuta komanso nthawi yayitali ya maphunziro.

Contraindication

Sayenera kumwedwa:

• Pankhani yamavuto a chida chachipatala,
• Odwala ndi gout
• Anthu omwe ali ndi matenda osiyanasiyana a impso,
• Ndi urolithiasis,
• Amayi omwe ali m'malo ndi yoyamwitsa,
• Ana osakwana zaka 3 ndi masekeli osakwana 20.

Zotsatira zoyipa

• Zovuta za chapakati mantha dongosolo - mutu, kukwaniritsa mwachangu kumva kutopa,
• Ntchito yosakhazikika pamtumbo wam'mimba - mavuto ndi kusowa kwa chakudya, kusanza, kutsegula m'mimba,
• Mavuto a musculoskeletal system - ululu wolumikizika,
• Chifuwa - kuphimba khungu ndi zotupa, urticaria.

Kodi imwani isoprinosine?

Malangizo ogwiritsira ntchito mapiritsi a akulu ndi ana:

- Akulu osachepera 500 mg osapitirira 4 g patsiku,

- Mlingo wa ana osakwana zaka 12 wazaka zowerengeka umawerengedwa ndi formula 50 mg pa kilogalamu ya thupi patsiku.

- Kwa akulu ndi ana, kuchuluka kwa mankhwalawa kumaloledwa kwa mitundu yayikulu yamatenda pa zifukwa zamankhwala. Zomwezi zimagwiranso ntchito pafupipafupi pakukonzekera, nthawi yayitali ya mankhwala.

Zodziwika bwino za chithandizo chamankhwala

• Kuchita bwino kwa mankhwalawa kumawonjezeka ngati mankhwalawa ayamba kuyambira masiku oyamba a matendawa.
• Ndikofunikira kuyang'anira kuchuluka kwa uric acid mkodzo ndi magazi, makamaka kwa odwala omwe ali ndi matenda a hepatic,
• Oyendetsa magalimoto ndi njira zina zomwe zimafunikira chisamaliro chapadera ayenera kudziwa kuti mankhwalawa angakhudze zochitika zawo, ndikupangitsa chizungulire komanso kukonzekera kugona. Izi zitha kusokoneza chitetezo.

Kuchita ndi mankhwala ena

• Zofanana makonzedwe a immunosuppressants amachepetsa mphamvu ya isoprinosine,
• Kugwiritsidwa ntchito kwa allopurinol ndi ma diuretics osiyanasiyana, kuphatikizapo furosemide ndi ethaconic acid, kumapangitsa kuchuluka kwa uric acid m'magazi,
• Kugwiritsa ntchito zidovudine palimodzi kumawonjezera kuchuluka kwa zidovudine m'magazi.

Mndandanda wamapiritsi omwe akupezeka ku Russia ndi kwina

Amiksin - (Wopanga ku Russia)

Makamaka amalimbana ndi matenda a herpetic, ma hepatitis A, B, C, chimfine ndi SARS. Amadziwika ndi kuthekera kuthana ndi ma sclerosis ambiri, urogenital ndi kupuma chlamydia.

Zotsatira zoyipa zamagetsi zimachitika mwangozi. Kuphatikiza apo, thupi siligwirizana.

Lavomax - (generic)

Zimagwirizana kwathunthu, zonse zikuchokera ndikuchita ndi chida chapita. Monga Amixin, ndikofunikira kuti pakhale nkhondo ya hepatitis, herpes. Kuphatikiza apo, imalimbana ndi ma sclerosis ambiri, fuluwenza ndi SARS.

Mwanjira yazinthu zopweteka zamkati, chifuwa, matumbo, komanso kumva kwanyengo siziperekedwa.

Ergoferon - (analogue yotsika mtengo yaku Russia)

Chithandizo chodziwika bwino cha antiviral chokhala ndi mndandanda wambiri wosonyeza. Kuchita kwake kumaphatikiza njira zodzitetezera ndi kuchizira fuluwenza A, B, matenda opatsirana pachimake opatsirana.

Zimathandizanso kuthana ndi matenda a herpesvirus. Ergoferon amadziwika ndi nkhondo yolimbana ndi zolakwika zam'mimba, zomwe zidakhumudwitsidwa ndi ma virus osiyana siyana.

Amalepheretsa ndi kupewa meningitis, chibayo, kuzungulira chifuwa.

Tilaxin - (Russia)

Ili ndi zofanana ndi Amiksin ndi Lavomaks. Amagwira matenda opatsirana pachimake opatsirana, fuluwenza, hepatitis, herpes. Amatinso kukonza ngati chithandizo cha encephalomyelitis, chlamydia, chifuwa chachikulu cha m'mapapo.

Zotsatira zoyipa za thupi la wodwalayo ndizosokoneza m'matumbo am'mimba, kuzizira kwakanthawi ndi chifuwa.

Alpizarin - (RF)

Imakhala ndi matenda a pakhungu ndi mucous nembanemba omwe amayambitsidwa ndi kachilombo ka herpes. Amatsutsana ndi Kaposi's sarcoma, ma warts, ma dermatoses a viral, kuphatikiza ndere.

Imayimiranso mndandanda wake wazotsatira zoyipa. Kusintha, kufooka matumbo, migraine, kutopa, zotupa za pakhungu kumachitika.

Malingaliro okhudza zamagetsi zotsika mtengo komanso zotsika mtengo

Popeza taganizirani za mankhwala oletsa kubereka, nkoyenera kunena mwachidule kuti ali ndi mbiri yabwino pamsika wamankhwala azitsamba. Nthawi yomweyo, mitengo ya Isoprinosine ndiyokwera kwambiri ndipo ingakhudze odwala.

Pamsika wamakampani, makampani opanga mankhwala ayambitsa kupanga mitundu yama generic pamtengo wotsika mtengo.

Musanagule wogwirizira, muyenera kupita kwa dokotala wa matenda opatsirana, omwe, popeza adatsimikiza kale matendawa, akhazikitsa njira yothandizira.

Mndandanda wa mankhwala Fraxiparin

Calcium ya Nadroparin
Sindikizani mndandanda wazofanana
Nadroparin calcium (Nadroparin calcium) Anticoagulant yankho mwachindunji kwa subcutaneous makonzedwe

Ili ndi mphamvu ya antithrombotic. Otsika maselo olemera heparin omwe amachokera ku njira yokhazikikayi ya depolymerization.

Pokhudzana ndi antithrombin III, imadziwika ndi ntchito motsutsana ndi factor XA komanso yofooka motsutsana ndi factor IIa.

Imathandizira kutsika kwa antithrombin III pa factor XA, yomwe imapangitsa kusintha kwa prothrombin kuti thrombin. Kuletsa kwa factor XA kumawonekera pamakonzedwe a 200 PIECES / mg, thrombin - 50 PIECES / mg. Ntchito za Anti-XA zimatchulidwa kwambiri kuposa momwe zimakhalira pa APTT. Ili ndi mphamvu yachangu komanso yokhalitsa. Zochita zikuwonetsedwa m'magulu a European Pharmacopoeia (Ph. Eur.) IU-anti-Xa.

Imakhala ndi anti-yotupa komanso immunosuppress (imalepheretsa mgwirizano wamtundu wa T- ndi B-lymphocyte), imachepetsa pang'ono kuchuluka kwa cholesterol ndi beta-lipoproteins mu seramu yamagazi. Amasintha magazi.

Kupewa kwa zovuta za thromboembolic (kuphatikiza ndi omwe amaphatikizidwa ndi opaleshoni yayikulu, oncology ndi orthopedics, mwa odwala omwe sanachite opaleshoni omwe ali ndi chiopsezo chachikulu cha thromboembolism: kupuma kwapafupipafupi, kulephera kwa puritis-septic, kulephera kwamtima), kupewa magazi kuundana pa hemodialysis.

Chithandizo cha thrombosis ndi thromboembolism, angina osakhazikika ndi infarction ya myocardial yopanda mafunde a Q.

Ntchito ndi mlingo

Lowani mu tinthu tating'onoting'ono tokhala m'mimba, m'makulidwe amkhungu (singano ndiyowonekera pakhungu lanu). Khola limasungidwa nthawi yonse yoyendetsa.

Kupewa kwa thromboembolism mu opaleshoni yayikulu: 0,3 ml 1 nthawi patsiku. 0,3 ml imayendetsedwa kwa maola 2-4 musanachite opareshoni. Njira ya mankhwala osachepera masiku 7.

Mwa njira zochizira: kutumikiridwa 2 pa tsiku kwa masiku 10 pa 225 IU / kg (100 IU / kg), yomwe ikufanana ndi: 45-55 kg - 0,4-0.5 ml, 55-70 kg - 0.5-0.6 ml, 70 -80 makilogalamu - 0,6-0.7 ml, 80-100 kg - 0,8 ml, oposa 100 kg - 0,9 ml.

Mu opaleshoni yamatsenga, mlingo umasankhidwa kutengera kulemera kwa thupi. Imaperekedwa kamodzi patsiku, tsiku lililonse: Mlingo wochepera 50 makilogalamu: munthawi ya opareshoni ndipo pakatha masiku atatu atachitidwa opaleshoni - 0,2 ml, mu nthawi ya postoperative (kuyambira masiku 4) - 0,3 ml.

Ndi thupi lolemera 51 mpaka 70 makilogalamu: mu nthawi ya ntchito ndipo pakatha masiku atatu atachitidwa opaleshoni - 0,3 ml, munthawi ya ntchito (kuyambira masiku 4) - 0,4 ml. Ndi thupi lolemera makilogalamu 71 mpaka 95: mu nthawi ya ntchito ndipo pakatha masiku atatu atachitidwa opareshoni - 0.

4 ml, mu nthawi ya postoperative (kuyambira masiku 4) - 0,6 ml.

Pambuyo pa venograph, imayendetsedwa maola 12 aliwonse kwa masiku 10, mlingo umadalira thupi: ndi kulemera kwa makilogalamu 45 - 0,4 ml, 55 kg - 0,5 ml, 70 kg - 0,6 ml, 80 kg - 0,7 ml, 90 kg - 0,8 ml, 100 makilogalamu ndi zina - 0,9 ml.

Pochiza matenda osakhazikika a angina pectoris ndi myocardial infarction popanda Q wave, 0,6 ml (5700 IU antiXa) amatumikiridwa katatu patsiku.

Mankhwala

Njira yamachitidwe Calcium nadroparin ndi heparin yotsika kwambiri ya maselo (LMWH) yomwe imapezeka ndi depolymerization kuchokera ku heparin yodziwika.Ndi glycosaminoglycan yokhala ndi kulemera pafupifupi mamiliyoni pafupifupi 4300 dalton.

Nadroparin amawonetsa kuthekera kwakukulu kumangiriza mapuloteni a plasma ndi antithrombin III (AT III). Kumangiriza kumeneku kumabweretsa kuyendetsa patsogolo kwambiri kwa factor Xa. zomwe zimachitika chifukwa cha kuthekera kwakukulu kwa nadroparin. Njira zina zomwe zimapereka antithrombotic mphamvu ya nadroparin.

liphatikize kutsegula kwa minyewa yotulutsa minyewa (TFPI), kutsegula kwa fibrinogenesis potulutsa mwachindunji gawo la plasminogen activator kuchokera ku maselo a endothelial, ndikusinthidwa kwa rheology ya magazi (kuchepa kwa kukhudzika kwa magazi ndi kuchuluka kwa kuphatikizika kwa maphatikizidwe am'magazi ndi granulocyte membranes).

Mankhwala Nadroparin amadziwika ndi ntchito zapamwamba motsutsana ndi factor XA, poyerekeza ndi zochita motsutsana ndi factor IIa. Imakhala ndi zochita za antithrombotic nthawi yomweyo komanso nthawi yayitali.

Poyerekeza ndi heparin yopanda kukonzekera, nadroparin imakhala yocheperako pakugwira ntchito ya platelet komanso kuphatikiza ndipo imakhudza kwambiri he hetasis ya pulayimale.

Mu Mlingo wa prophylactic, sizimapangitsa kuchepa kutchulidwa kwakanthawi kokhazikika kwa nthawi ya thrombin (APTT).

Ndi njira ya chithandizo munthawi ya zochita zochuluka, APTT imatha kuwonjezeka mpaka mtengo wapatali maulendo 1.4 kuposa muyeso. Kutalika koteroko kumawonetsera otsalira a antithrombotic mphamvu ya calcium nadroparin.

Pharmacokinetics Facacokinetic katundu amatsimikiza pamaziko a kusintha kwa ntchito ya anti-Xa chinthu cha plasma.

Pambuyo pa kayendetsedwe ka subcutaneous, ntchito yapamwamba yotsutsana ndi Xa (C max) imatheka pambuyo pa maola 35 (T max).
Bioavailability Pambuyo subcutaneous makonzedwe, nadroparin pafupifupi odzipereka kwathunthu (pafupifupi 88%).

Ndi makonzedwe othandizira, ntchito yolimbana kwambiri ndi Xa imakwaniritsidwa osakwana mphindi 10, theka-moyo (T½) ndi pafupifupi maola awiri.

Metabolism Metabolism imachitika makamaka m'chiwindi (desulfation, depolymerization).

Hafu ya moyo pambuyo subcutaneous makonzedwe ndi pafupifupi maola 3.5. Komabe, ntchito anti-Xa amalimbikira kwa maola osachepera 18 pambuyo jekeseni wa nadroparin muyezo wa 1900 anti-XA ME.

Magulu owopsa

Odwala okalamba
Odwala okalamba, chifukwa cha kuchepa kwa impso, kuchotsedwa kwa nadroparin kumachepetsa. Kulephera kwa impso m'gululi la odwala kumafunika kuwunikira komanso kusintha koyenera kwa mlingo.

Odwala ndi mkhutu aimpso ntchito Mu matenda maphunziro a pharmacokinetics a nadroparin kuperekedwa kwa odwala ndi aimpso kulephera osiyanasiyana zovuta, malumikizidwe anakhazikitsidwa pakati pa chilolezo cha nadroparin komanso chilolezo cha creatinine.

Poyerekeza zomwe zapezedwa ndi zomwe odzipereka athanzi labwino, zidapezeka kuti AUC ndi theka la moyo adachulukitsidwa mpaka 52-87%, ndikupanga chilolezo cha creatinine mpaka 47-64% ya zinthu wamba. Kafukufukuyu adawonezeranso kusiyana kwakukulu pamunthu payekha.

Odwala kwambiri aimpso kulephera, theka moyo wa nadroparin ndi subcutaneous makonzedwe kuchuluka kwa 6 maola.

Zotsatira za kafukufukuyu zikuwonetsa kuti kuchulukana pang'ono kwa nadroparin kumatha kuwonedwa mwa odwala omwe ali ndi vuto lochepa kapena ochepa aimpso (kulengedwa kwa creatinine kumakhala kwakukulu kuposa kapena kofanana ndi Som / min komanso ochepera 60 ml / min), motero, mlingo wa Fraxiparin uyenera kuchepetsedwa ndi 25% mwa odwala omwe amalandira Fraxiparin zochizira thromboembolism, osakhazikika angina pectoris / myocardial infarction popanda Q wave. Fraxiparin imayikidwa mwa odwala omwe ali ndi vuto lalikulu laimpso, pofuna kuthana ndi mikhalidwe. Odwala omwe ali ndi vuto lochepa kapena aimpso kulephera, kugwiritsa ntchito Fraxiparin pofuna kupewa thromboembolism, kudzikundikira kwa nadroparin sikudutsa kuti odwala omwe ali ndi vuto laimpso, amatenga muyezo waukulu wa Fraxiparin. Chifukwa chake, kuchepetsa mlingo wa Fraxiparin wotengedwa chifukwa cha prophylactic m'gulu lino la odwala sofunikira. Odwala kwambiri aimpso kulephera kulandira prophylactic fraxiparin, kuchepetsa 25% ndikofunikira poyerekeza ndi Mlingo womwe umaperekedwa kwa odwala omwe ali ndi chizolowezi cha creatinine chilolezo.

Mochepa heparin wama hematin amayamba mu ochepa mzere wa dialysis kuzungulira muyezo wokwanira kuteteza magazi kuunjikana. Magawo a Pharmacokinetic sasintha kwenikweni, kupatula mankhwala osokoneza bongo, pomwe kudutsa kwa mankhwalawo m'thupi mwake kungayambitse kuwonjezeka kwa ntchito ya anti-Xa yomwe ikugwirizana ndi gawo lomaliza la kulephera kwa aimpso.

Fraxiparin analog

chuma changa (dzulo)

Kodi pali kusiyana kofunikira ..

Atsikana, kodi pali kusiyana kulikonse pakati pa Clexane ndi Fraxipain? Tsopano ndikumenya Kleksan ndi dokotala wazachipatala wa 0,4 (sizikudziwika kuti ndichifukwa chiyani wazachipatala amawasankha)? (Kwa wazam'tsogolo pa Lachiwiri 13) Ndinayamba kulankhula zosinthira ku 0.6.

Dzulo ndidapita wina 0,4, ndiye zingandipeze ndalama zingati 0.6 ngati. Atsikana 816 rubles, i.e. kwa dazeni, amafunika kuti adulidwe m'chigawo cha rubles 10,000. Ine sindine mwana wamkazi wa mamiliyoni ambiri ndipo sindimakhala ndi makina osindikizira kaya, ngakhale atakhala omangika bwanji, ndikuganiza kuti sakhala mwa aliyense.

LCD imapereka chiwonetsero cha fraxiparin

Atsikana omwe amapaka jekeseni wa fraxiparin ndi clexane kukhala woyembekezera? Mankhwalawa apatsidwe kwa ine mu LCD, koma akuti sanapezeke ndipo akufuna kulemba zina, sindinali ndi nthawi yolemba dzinali pa kaphikidwe (sanandipatsebe).

Amati ndi zofanana. Koma zikadakhala choncho, ndiye kuti dotolo (dotoloyo sanali kupereka mankhwala kuchokera ku LCD) poyamba akanalemba mndandanda wonse wa mankhwala omwe nditha kugwiritsa ntchito, ndipo adangolembera a ftyxiparin ndi clexane okha.

Ma Analogs amatha kukhala ndi zotsatirapo zabwino ...

MALO OGWIRITSA MTHAZI

Fraxiparin, Clexane, malangizo a Wessel Douai ogwiritsira ntchito, mitengo, analogues

Werengani zambiri ... Olga (amayi a Vova)

Hemopaxan ngati analogue ya Fraxiparin

Mu LCD yanga, ndinapatsidwa mankhwala a Hemopaxan aulere, omwe akuwoneka kuti ndi analogue a Fraxiparin. Kodi pali amene wamvapo za mankhwalawa? Kwenikweni analog? Adanenanso kuti kuyesera izi pachiwopsezo chanu komanso pangozi yanu.

Wokondedwa wa Fraxiparin, adandipatsa hematologist kuti "zitha", kuti ndimutsimikizire kuti oxygen kwa mwana ukuyenda popanda mavuto ... .. Ndikuganiza zoyesa, koma chifukwa

Sindikudziwa chilichonse chokhudza mankhwalawa - ndidaganiza zofunsidwa pa forum ...

Khalendala Yapakati pa Mimba

Tikuuzani nkhani zenizeni za amayi athu omwe adutsa izi kapena akudutsa pakali pano!

Fraxiparin ndi kampani

Sanatenge mayeso apadera, onse omwewo, fraksiparin adasankhidwa. Malinga ndi kafukufuku wina, kuwerengera kwa mapulateleti kudakulitsidwa pang'ono. Sindinacheze ndi hematologist ndipo, makamaka, palibe njira zochezera. Pali mafunso angapo. Adotolo akuti "ndiyenera" ndi china chilichonse monga choncho.

Palibe konkriti. Sindingathe kusintha dokotala.

1) tsopano wathetsa mimba? 2) chidzachitike ndi chiani ndikaponya jakisoni kwa masiku angapo? Mwachitsanzo, ngati palibe mankhwala mu mankhwala aliwonse 3) kodi ndizomveka kutenga hemostasiogram? Ndikupita kuti?

Ndigulitsa Zibor 3500! Moscow Zalonjezedwa

Atsikana, ndimagulitsa analogue ya clexane ndi fraksiparin. Adandiyandikira zowonjezera, ngakhale zidakhala zovuta kupeza. Anagwedeza mimba yonseyi !! Tsibor 3500 ma PC 5 a 1000 r. Yovomerezeka mpaka 05.2016.

Ndinagula kumapeto kwa Ogasiti ndisanabadwe ma PC 10 kwa 3550 p. Nditha kupatsa corinfar pafupifupi yodzaza ndi chithuza cha genipral kuwonjezera. Zibor pambuyo pa protocol yopambana, zomwe ndi zomwe ndikukhumba aliyense! Moscow Nastya. Tele 8-926-93-67-560.

Nyamula ku metro station Yuzhnaya masabata ...

Fotokozerani mutu wanu pagulu, pezani malingaliro a ogwiritsa ntchito a Babloglog

Pitani pagulu

Olga (amayi a Vovchik)

Magazi kuchokera pamphuno pambuyo pa jekeseni kuti muchepetse magazi

Dzulo chinali jekeseni womaliza wa 21 wa Gemapaksan, yemwe amandiuza "kwa aliyense wazoyimitsa moto", uku ndi fanizo la Fraksiparin, tanthauzo lake ndikuchepa kwa magazi. Hemostasis pakati pa jakisoni anali bwino, koma .... dzulo ndi lero, mphuno zimatuluka mwadzidzidzi.

Osatinso ma drows ochepa, koma kasupe wokha! Ndipo sanayime kwa nthawi yayitali. Zachidziwikire kuti ndimachita mantha.

Kodi ndikugwirizanitsa izi ndi majekeseni a Gemapaksan? Kodi pali chiyembekezo chilichonse choti kufafaniza jakisoni (sindingachite lero) zamanyazi zija zitha? Izi sizinachitikepo kale .......

Werengani zambiri ... Amayi ku Cuba

Ndilandira ngati mphatso kapena kusinthanitsa ndi mankhwala! Moscow!

Atsikana okondeka, ndikupemphani mphatso kapena kusinthana ndi wina, zomwe zatsalira pambuyo pa kukondweretsedwa?! Tikufuna kusintha kwa menopur (kapena zithunzi zake), kuyendetsedwa mu syringes, cytrocide, orgalutran, kuzungulira! Chikondwerero cha Chisanu ndi chiwiri (IVF), mwatsoka, sitinakhalepo ndi chipale chofewa, chifukwa Mimbulu ya 1-3 imakhalabe ndi moyo, kusamutsa yonse, kotero muyenera kuyika ma protocol nthawi iliyonse yatsopano! Mwinanso china chake chimayenera kusinthidwa, ndikuwona zomwe ndili nazo kuchokera ku mankhwala anga othandizira kutenga pakati (Utrozhestan, Clexane, Fraxiparin!? ...

Ndimapereka mankhwala othandizira omwe ali mu protocol

Ndimapereka mankhwala othandizira mu protocol ya chindapusa cha Fraxiparin 0,3 1 pc.CHELETE mpaka 06.2015! Clexane 0.8 ml 2 ma PC mpaka 01.2017 PASSED Analogue ya clexane edema mankhwala Anfibra (ambiri) mu ampoules a 0.6 ml ndi 0,4 ml adzaperekedwa kwa iwo omwe akufunika kulipira mseu (wotengedwa pano kuchokera ku Elena), osathandiza, kwathetsedwa!! Nyamulani siteshoni ya metvedkovo metro

fraxiparin kapena aspirin Cardio?!

Atsikana, chonde ndifotokozereni, apo ayi mutu wanga ukutuluka. Dokotala wanga amakaumirira kuti jakisoni wa fakisoni (jekeseni kamodzi pa masiku asanu ndi awiri) m'malo mwake ndi aspirin-Cardio kapena mawonekedwe ake mapiritsi 100 mg usiku tsiku lililonse.

Sindikumvetsa chifukwa chiyani? Samalongosola kwenikweni. Amanena zina monga momwe kapangidwe ka fraxiparin palokha kamasinthira ndipo nthawi zina amatsogolera ku zotsatira zina, ndiye kuti, sawonda magazi, koma amayambitsa magazi. Monga china chatsopano chamankhwala.

Kodi izi ndi zowona? Nditatenga mwana wanga ...

Anfibre m'malo mwa clexane, ndani adalowetsa?

Atsikana omwe ali pa clexane kapena fraxiparin ndi mankhwala ofananawa amandiuza. Ndimagwiritsa ntchito clexane nthawi zonse, ndipo lero ku ZhK adapereka analogue yotsika mtengo yaku Russia ya mankhwalawa, Anfibra, zomwe zimagwira ntchito, etc. Omwe adakumana Malingaliro anu okhudza iye, kapena mwina akatswiri a zamankhwala anampatsa winawake?

Kukonzekera pambuyo pa eco, Ukraine

Gulitsa / gulitsa utrozhestan, progina, kleksan, fragmentin, Kiev Price300 UAH. 05/18/2017 09:27 Dera: Kiev (Kiev) Ndigulitsa zotsalira za mankhwala: Utrozhestan 100mg ndi yovomerezeka mpaka 08/08 - 300 UAH pali mapaketi 4.

Proginova 2mg ndiyabwino mpaka 2020, pali maphukusi awiri a 200 UAH iliyonse. Clexane 0.2ml ndi yovomerezeka mpaka 09.2018, pali ma syringe 20 - 60 UAH pa syringe imodzi. Fragmin 2500me (analogue of clexane and fraxiparin) ndi yovomerezeka mpaka 09.

2018, pali 18 shrishchov- 70 UAH wa jekeseni wa Papaverine wa syringe ndi woyenera ...

Za mankhwala odula. Ulendo wanga wotsatira ku LCD,

Nditalandira malangizo kuchokera kuDipatimenti ya ZhK kuti ndikufuna mankhwala, ndinapita ku ZhK. Mu Januware, adalemba analogue ya Fraxiparin Anfibra, koma m'malo mwa 0.6 ml yomwe ndimafunikira, adandipatsa 0.4 yokha.

Nditabwera kuti ndisungidwe ndipo adotolo atawona heestasis yanga, nthawi yomweyo adanena kuti 0.6 ikufunika. Mu February, malinga ndi mutu. nthambi idandilamula kuti ndimupatse ma ampoules 30 of 0.6 lililonse kwa adokotala.Dotolo adapereka mankhwala kwa ma ampoules a 30. Koma zoona zake zidali zoti 20 okha adalamulidwa.

Sakufunanso kupereka. Pita, akuti, lembanso chinsinsi. Ndinayenera kupita pansi pa 3 ...

Innogep, fraksiparin, clexane - ndizotheka kusintha wina ndi mnzake?

Moni anyamata! Apanso popanda thandizo lanu komanso luso lanu mwanjira iliyonse. Malangizo othandizira! Ndili ndi thrombophilia ndipo chifukwa cha izi, ndiyenera kupereka jakisoni wa heparin yotsika kwambiri m'mimba mwanga wonse. Tsopano (masabata 15) ndimakantha Innogep 4500 - ku Greece.

Koma ndi nthawi yoti mubwerere ku Russia, ndipo palibe mankhwalawa (ndikuganiza kuti chifukwa cha zigawenga) ndi mgwirizano wake ndi sodium yogwira tinzaparin sodium. Koma ku Russia kuli Fraksiparin (ndinali nditabaya jakisoni wanga woyamba) ndi Kleksan. Koma palinso zinthu zina zomwe zingagwire ntchito.

Mmodzi wa inu panthawi yoyembekezera ...

Chithandizo changa pambuyo pa cryoprotection

Fraxiparin: malangizo, masinthidwe, analogi, zikuonetsa, contraindication, kukula ndi Mlingo

Calcium Nadroparin * (Nadroparin calcium *) Anticoagulants

020 (Direct-akuchita anticoagulant - ochepa maselo wolemera heparin)

Njira yothetsera kuyang'anira sc ndi yowonekera, pang'ono opalescent, wopanda mtundu kapena kuwala wachikaso.

Omwe amathandizira: calcium hydroxide solution kapena kuchepetsa hydrochloric acid (mpaka pH 5.0-7.5), d / i madzi (mpaka 0.3 ml).

0,3 ml - syringes ya single-2 (-) - matuza (1) - matumba a makatoni; 0,3 ml - syringes imodzi (2) - matuza (5) - mapaketi a makatoni.

Njira yothetsera kuyang'anira sc ndi yowonekera, pang'ono opalescent, wopanda mtundu kapena kuwala wachikaso.

Omwe amathandizira: calcium hydroxide solution kapena kuchepetsa hydrochloric acid (mpaka pH 5.0-7.5), d / i madzi (mpaka 0.4 ml).

0,4 ml - syringes ya single-2 (-) - matuza (1) - matumba a makatoni. 0.4 ml - syringes imodzi (2) - matuza (5) - mapaketi a makatoni.

Njira yothetsera kuyang'anira sc ndi yowonekera, pang'ono opalescent, wopanda mtundu kapena kuwala wachikaso.

Omwe amathandizira: calcium hydroxide solution kapena kuchepetsa hydrochloric acid (mpaka pH 5.0-7.5), d / i madzi (mpaka 0.6 ml).

0,6 ml - syringes ya single-2 (-) - matuza (1) - mapaketi a makatoni; 0.6 ml - syringes imodzi (2) - matuza (5) - mapaketi a makatoni.

Njira yothetsera kuyang'anira sc ndi yowonekera, pang'ono opalescent, wopanda mtundu kapena kuwala wachikaso.

Omwe amathandizira: calcium hydroxide solution kapena kuchepetsa hydrochloric acid (mpaka pH 5.0-7.5), d / i madzi (mpaka 0.8 ml).

0,8 ml - syringes ya single-2 (2) - matuza (1) - mapaketi a makatoni; 0,8 ml - syringes imodzi (2) - matuza (5) - mapaketi a makatoni.

Njira yothetsera kuyang'anira sc ndi yowonekera, pang'ono opalescent, wopanda mtundu kapena kuwala wachikaso.

Omwe amathandizira: calcium hydroxide solution kapena kuchepetsa hydrochloric acid (mpaka pH 5.0-7.5), d / i madzi (mpaka 1 ml).

1 ml - ma syringes a limodzi - 2 - - matuza (1) - matumba a makatoni 1 ml - ma syringes amodzi (2) - matuza (5) - mapaketi a makatoni.

Fraxiparin analogues

Malangizo pa kugwiritsa ntchito mankhwala Fraxiparin

Zotsatira za pharmacological
Calcium nadroparin (chophatikizira cha Fraxiparin) ndi heparin yotsika kwambiri yochokera ku heparin yodziwika bwino mwa kupezeka kwa zinthu zina. Mankhwala amadziwika ndi ntchito yotsutsana ndi coagulation factor Xa ndi ntchito yofooka motsutsana ndi factor Pa. Ntchito ya Angi-Xa (i.e., antiplatelet / kuphatikizika kwa maselo othandizira / ntchito) ya mankhwalawa imatchulidwa kwambiri kuposa momwe imayendera nthawi yodziyimira yogwira maselo othandiza magazi kuundana (chizindikiritso cha kuchuluka kwa magazi), omwe amasiyanitsa calcium ndi nadroparin calcium kuchokera ku heparin yodziwika bwino. Chifukwa chake, mankhwalawa • ali ndi ntchito ya antithrombotic (kuletsa mapangidwe a magazi), ndipo imagwira mwachangu komanso mokhalitsa.

Zizindikiro zogwiritsidwa ntchito
Kugwiritsa ntchito Fraxiparin ndikulimbikitsidwa:

• kupewa matenda obisika a m'mitsempha. Odwala omwe akupita kuchipatala iliac angina pectoris ndi infaration ya myocardial yopanda Q wave pa ECG.

Njira yogwiritsira ntchito
Fraxiparin lakonzedwa kuti subcutaneous ndipo

intravenous makonzedwe. Osagwiritsa ntchito Fraxiparin intramuscularly. Ndi kukhazikitsidwa kwa Fraxiparin, sikungaphatikizidwe ndi mankhwala ena. Kuteteza kwa zovuta za thromboembolic General opaleshoni. Mulingo woyenera wovomerezeka ndi 0,3 ml wa Fraxiparin kamodzi patsiku, masiku osachepera 7. Mulimonsemo, kupewa kuyenera kuchitika panthawi yamavuto.

Mlingo woyamba umaperekedwa kwa maola 2 mpaka 4 asanachitidwe opaleshoni. Mlingo woyamba wa Fraxiparin umaperekedwa kwa maola 12 musanachite opareshoni ndi maola 12 pambuyo pake. Kugwiritsa ntchito mankhwalawa kupitilirabe kwa masiku 10. Mulimonsemo, kupewa kuyenera kuchitika panthawi yamavuto.