Malangizo a mtengo wa Amoxiclav 1000 mg kuti mugwiritse ntchito

Antibiotic Amoxiclav 1000 ndi mankhwala ogwiritsa ntchito polimbana ndi ma virus okhala ndi mawonekedwe osiyanasiyana ochita zinthu motsutsana ndi unyinji wa mabakiteriya. Zimaphatikizanso kuchokera ku ampicillin (kapena amoxicillin) + clavulanic acid. Ntchito yotsirizira ndikuyimitsa kuyimitsidwa kwa enzymatic kwa penicillin kudzera mukulumikizana ndi bakiteriya a lactamases.

Kapangidwe ka amoxiclav 1000 mg

Amoxiclav 1000 ili ndi zinthu izi:

Amoxicillin (monga ma hydrocrate) - 875 mg,
Clavulanic acid (munthawi ya clavulalacotassium) - 125 mg.

Crospovidone
Silicon dioxide
Magnesium wakuba,
Talc,
Ma cellulose pama microcrystals,
Croscamellose sodium.

Kuphimba kwa mafilimu kumakhala ndi izi: titanium dioxide, macrogol 6000, diethyl phthalate, hypromellose, ethyl cellulose.

Amoxiclav 1000 imalowetsedwa bwino m'magazi, mosasamala nthawi yakudya. Kuphatikiza kwakukulu m'magazi kumapangidwa pambuyo pa ola limodzi logwiritsira ntchito mankhwalawa. Mwachikhalidwe, njira yochizira imatenga masiku 5 mpaka 10. Kwa milungu yopitilira iwiri, mankhwalawa sayenera kumwa popanda kuuzidwa ndi dokotala.

Kodi nambala 1000 yotchulidwa ndi mankhwalawa ikutanthauza chiyani? Izi zikutanthauza kuti piritsi limodzi lili ndi 875 mg ya antiotic (amoxicillin) ndi 125 mg ya clavulanic acid. Pazonse, padzakhala miliyoni mg kapena 1 g.

Kutulutsa mawonekedwe ndi kufotokozera

Mankhwala amapezeka mu mawonekedwe a mapiritsi a zidutswa 14 papaketi iliyonse. Mapiritsi a 1000 mg ndi oyera kapena pafupifupi oyera, oblong, mapiritsi a biconvex, filimu wokutira, wokhala ndi notch komanso chithunzi cha "875/125" mbali imodzi ndi "AMS" mbali inayo.

Zida zazikulu zomwe zimagwiritsa ntchito mankhwalawa ndi amooticillin (mankhwala opangidwa ndi penicillin gulu) ndi clavulanic acid (choletsa ma enzyme ya bakiteriya yomwe imawononga penicillin ndi analogues - β-lactamase. Zinthu zothandizazi zimathandizira kuti ntchito ya mankhwalawa igwiritsidwe mabakiteriya osiyanasiyana.

Piritsi limodzi la Amoxiclav, lomwe lili ndi Mlingo wa 1000 mg lili ndi zinthu zake:

amoxicillin (monga amoxicillin trihydrate) 875 mg
clavulanic acid (monga potaziyamu clavulanate) 125 mg

Komanso mapiritsi amakhala ndi zinthu zothandiza:

Silicon dioxide colloidal amadzimadzi.
Crospovidone.
Magnesium wakuba.
Croscarmellose sodium.
Microcrystalline mapadi.
Cell ya Ethyl.
Polysorbate.
Talc.
Titanium dioxide (E171).

Kuchuluka kwa mapiritsi amodzi mu phukusi limodzi la Amoxiclav lakonzedwa kuti pakhale mankhwala ochepetsa mphamvu ya antibayotiki. Mlingo wosiyanasiyana umakupatsani mwayi wosinthira kuchuluka kwa maantibayotiki pakugwiritsa ntchito.

Zizindikiro zogwiritsidwa ntchito

Ngati mungawerenge malangizo ogwiritsira ntchito Amoxiclav 1000, mutha kudziwa kuti ndi othandiza mankhwalawa:

Sinusitis
Otitis
Pharyngitis
Tonsillitis
Matenda opatsirana
Pachimake bronchitis
Chibayo
Zofoka
Kutupa kwa pakhungu
Kutupa kwakhungu komwe kumayambitsidwa ndi kulumidwa kwanyama
Pyelonephritis,
Matenda amitsempha
Kutupa kwa matenda azitsamba,
Postpartum sepsis,
Kuchotsa mimbayo
Pelvioperitonitis,
Edipititis
Matenda opatsirana pogonana (matenda opatsirana pogonana),
Pofuna kupewa matenda nthawi ya opaleshoni.

Mankhwala

Amoxicillin ndi penicillin wopanga yemwe amagwira ntchito motsutsana ndi michere yambiri yama gramu-gram komanso yoyipa. Amoxicillin amasokoneza biosynthesis ya peptidoglycan, yomwe ndi gawo lachipangidwe cha khoma la bakiteriya. Kuphwanya kapangidwe ka peptidoglycan kumabweretsa kuwonongeka kwa mphamvu ya khungu, komwe kumayambitsa lasis ndi kufa kwama cellorganism. Nthawi yomweyo, amoxillin imayamba kuwonongeka ndi beta-lactamases, chifukwa chake ntchito yokhala ndi amoxicillin sinafikira tizilombo tomwe timatulutsa timadzi tambiri.

Clavulanic acid, beta-lactamase inhibitor yokhudzana ndi penicillin, amatha kuyambitsa mitundu yambiri ya beta-lactamases yomwe imapezeka mu penicillin ndi cephalosporin zosagwira tizilombo. Clavulanic acid ili ndi mphamvu yokwanira yolimbana ndi plasmid beta-lactamases, yomwe nthawi zambiri imayambitsa kukokana kwa bakiteriya, ndipo siigwira ntchito motsutsana ndi mtundu I chromosome beta-lactamases, womwe suletsedwa ndi clavulanic acid.

Kupezeka kwa clavulanic acid pakukonzekera kumateteza amoxicillin kuti asawonongeke ndi ma enzymes - beta-lactamases, omwe amalola kukula kwa antibacterial sipekitiramu ya amoxicillin.

Bacteria yemwe nthawi zambiri amamvera kuphatikiza kwa amoxicillin ndi clavulanic acid:

Ma gror-positive aerobes: Bacillus anthracis, Enterococcus faecalis, Listeria monocytogene, Nocardia asteroides, Streptococcus pyogenes ndi ena a beta-hemolytic streptococci1,2, Streptococcus agalactiae1,2, streycoccus aalus (tcheru ndi methicillin).
Ma gror-negative aerobes: Bordetella pertussis, Haemophilus influenzae1, Helicobacter pylori, Moraxella catarrhalis1, Neisseria gonorrhoeae, Pasteurella multocida, Vibrio cholerae.
Ena: Borrelia burgdorferi, Leptospira icterohaemorrhagiae, Treponema pallidum.
Ma anaerobes a gramu: mitundu ya mtundu wa Clostridium, Peptococcus niger, Peptostreptococcus magnus, Peptostreptococcus micros, mitundu ya genus Peptostreptococcus.
Gram-negative anaerobes: Bacteroides fragilis, mitundu ya genus Bacteroides, mitundu ya mtundu wa Capnocytophaga, Eikenella corrodens, Fusobacterium nucleatum, mitundu ya genus Porphyromonas, mitundu ya genus Porphyromonas, mitundu ya genus Prevotella.
Bacteria yomwe idayamba kukana kuphatikiza amoxicillin ndi clavulanic acid ndiyotheka
Mitundu ya grram-negative aerobes: Escherichia coli1, Klebsiella oxytoca, Klebsiella pneumoniae, mitundu ya mtundu wa Klebsiella, Proteus mirabilis, Proteus vulgaris, mitundu ya mtundu wa Proteus, mitundu ya mtundu wa Salmonella, mitundu ya mtundu wa Shigella.
Ma gror-positive aerobes: mitundu ya genus Corynebacterium, Enterococcus faecium, Streptococcus pneumoniae, streptococci of the Viridans group.

Kuzindikira ndi amoxicillin monotherapy kumasonyezanso chidwi chofanana ndi kuphatikiza kwa amoxicillin ndi clavulanic acid.

Zosakaniza zazikulu zomwe zimagwiritsa ntchito mankhwalawa zimachokera ku matumbo. Mwazi wawo umafika pachithandizo chambiri mkati mwa theka la ola mutatha kumwa mapiritsi, kuchuluka kwakukulu kumafikiridwa pafupifupi maola awiri. Zonsezi zimagawidwa mokwanira mu minyewa yonse ya thupi, kupatula ubongo, chingwe cha msana ndi madzi am'magazi (chithokomiro cham'mimba), popeza sizilowa mu chotchinga cha magazi (malinga ngati palibe njira yotupa m'matumbo athu). Komanso, amoxicillin ndi clavulanic acid amadutsa chikhodzodzo kulowa mwana wosabadwayo panthawi yoyembekezera ndikudutsa mkaka wa m'mawere panthawi ya mkaka wa m`mawere. Zinthu zofunikirazi zimakumbidwa makamaka ndi impso (90%) zosasinthika. Hafu ya moyo (kuchotsedwa kwa nthawi ya 50% ya chinthu kuchokera koyambirira kuzungulira thupi) ndi mphindi 60-70.

Amoxiclav 1000 mg motsutsana ndi ma virus

Kuchokera pamenepo aerobes (ma virus) Amoxiclav 1000 mg ndi othandiza:

Gram-positive (enterococci, staphylococci, streptococci),
Gram-hasi (Escherichia, Klebsiella, Moraxella, Haemophilus fuluwenza, Gonococcus, Shigella, Meningococcus).

Mapiritsi a Amoxiclav 1000 mg sagwira ntchito polimbana ndi ma virus:

Pseudomonas aeruginosa,
Tizilombo toyambitsa matenda a chracellular (chlamydia, mycoplasmas, legionella),
Methicillin osagwira staphylococci,
Bacteria: enterobacter, acytobacter, serrate.

Contraindication

Pali zochitika zina zomwe mapiritsi a Amoxiclav 1000 sangatenge:

Mononucleosis
Clavulanic acid ziwengo
Matenda a chiwindi
Cholestatic jaundice,
Khansa ya m'magazi
Kutsegula m'mimba
Zovuta zam'matumbo,
Colitis.

Mankhwalawa saikidwa kwa iwo omwe apezeka kuti ali ndi matenda a creatinine chilolezo chochepera 30 ml pa mphindi, kwa ana ochepera zaka 12, kwa odwala omwe ali ndi phenylketonuria. Chenjezo, kuyang'aniridwa ndi dokotala, amayi apakati, makamaka amayi omwe ali ndi vuto la impso, ayenera kugwiritsa ntchito mankhwalawa panthawi yoyamwitsa. Mosamala, imaperekedwa kwa iwo omwe amapezeka ndi vuto la chiwindi.

Mlingo wa mapiritsi a Amoxiclav kwa akuluakulu

Njira ndi Mlingo wa kugwiritsa ntchito Amoxiclav zimatsimikiziridwa ndi adotolo pamaziko a zinthu zambiri - kukonza, kuopsa kwa matenda opatsirana, kutengera kwake. Ndibwino kuchititsanso kuwunika kwawoko maubwino wa chithandizo cha mankhwala pogwiritsa ntchito maphunziro a bacteria.

Njira ya mankhwala ndi masiku 5-14. Kutalika kwa nthawi ya chithandizo akutsimikiza ndi dokotala. Kuchiza sikuyenera kupitirira masiku opitilira 14 popanda kupimidwa kachiwiri.

Popeza mapiritsi osakanikirana a amoxicillin ndi clavulanic acid a 250 mg + 125 mg ndi 500 mg + 125 mg ali ndi kuchuluka komweko kwa clavulanic acid -125 mg, mapiritsi 2 a 250 mg + 125 mg siofanana ndi piritsi limodzi la 500 mg + 125 mg.

Zotsatira zoyipa

Kumwa mapiritsi a Amoxiclav kumatha kubweretsa zovuta zingapo.

Kuchokera m'mimba thirakiti: pafupipafupi: kutsekula m'mimba, kawirikawiri: nseru, kusanza. Khansa ya msana imawonedwa kwambiri tikamayamwa. Ngati kuphwanya kwam'mimba kumatsimikiziridwa, kumatha kutha ngati mutamwa mankhwalawa koyambirira kwa chakudya. Pafupipafupi: kugaya chakudya m'mimba, kawirikawiri kwambiri: colitis yokhudzana ndi ma antibayotiki (kuphatikiza hemorrhagic colitis ndi pseudomembranous colitis), lilime la "tsitsi" lakuda, gastritis, stomatitis.

Kuchokera ku chiwindi ndi chithokomiro chamadongosolo: pafupipafupi: kuchuluka kwa ntchito kwa alanine aminotransferase (ALT) ndi / kapena aspartate aminotransferase (ACT). Izi zimawonedwa mwa odwala omwe amalandila beta-lactam antiotic therapy, koma kufunikira kwake kwachipatala sikudziwika. Osowa kwambiri: cholestatic jaundice, hepatitis, kuchuluka kwa zamkati phosphatase, kuchuluka kwa bilirubin m'madzi a m'magazi.

Zotsatira zoyipa za chiwindi zimawonedwa makamaka mwa abambo ndi odwala okalamba ndipo amatha kuyanjana ndi chithandizo cha nthawi yayitali. Zochitika zoyipa izi sizimawonedwa kawirikawiri mwa ana. Zizindikiro zomwe zalembedwazo zimakonda kuchitika pakumala kapena atangomaliza kumene chithandizo, komabe nthawi zina mwina sangawonekere kwa milungu ingapo atamaliza kulandira chithandizo. Zotsatira zoyipa nthawi zambiri zimatha kusintha. Zotsatira zoyipa za chiwindi zimatha kukhala zowopsa, nthawi zina pamakhala nkhani zakufa. Pafupifupi nthawi zonse, awa anali anthu omwe anali ndi vuto lalitali kapena omwe amamwa nthawi yomweyo mankhwala a hepatotoxic.

Kuchokera ku chitetezo chamthupi: kawirikawiri: angioedema, anaphylactic zimachitika, matupi awo saviyo vasculitis.

Kumbali ya magazi ndi dongosolo la lymphatic: kawirikawiri: leukopenia yosinthika (kuphatikizapo neutropenia), thrombocytopenia, kawirikawiri: kusinthika kwa agranulocytosis, hemolytic anemia, kuchuluka kosinthika kwa prothrombin nthawi, kuchuluka kwosinthika kwa nthawi ya magazi (onani gawo "Special Instructions"), eomboinophilia.

Kuchokera kwamitsempha yamanjenje: chizungulire: chizungulire, kupweteka mutu, kawirikawiri: kupweteka (kumachitika mwa odwala omwe ali ndi vuto laimpso, komanso pamene mukumwa mankhwalawa.) .

Pa khungu ndi subcutaneous zimakhala: pafupipafupi: zotupa pakhungu, kuyabwa, urticaria, kawirikawiri: exudative erythema multiforme, kawirikawiri: exfoliative dermatitis, Stevens-Johnson syndrome, pachimake exanteticous pustulosis, matenda ofanana ndi seramu matenda, poizoni epermermal necrolysis.

Kuchokera kumbali ya impso ndi kwamkodzo thirakiti: kawirikawiri: interstitial nephritis, crystalluria (onani gawo "Overdose"), hematuria.

Matenda opatsirana komanso majeremusi: nthawi zambiri: candidiasis a pakhungu ndi mucous nembanemba.

Malangizo apadera

Kugwiritsa ntchito mapiritsi a Amoxiclav 1000 kuyenera kuchitika pokhapokha malinga ndi dokotala. Ndikupangidwanso kuti muwerenge malangizo a mankhwalawo. Malangizo apadera okhudza kuperekera kwa mankhwalawa ayenera kukumbukiridwa:

Musanayambe kumwa, muyenera kuwonetsetsa kuti m'mbuyomu palibe zomwe zimachitika pakumwa mankhwala a gulu la penicillin ndi mitundu yake. Ngati ndi kotheka, ndikofunikira kuchita zoyeserera.
Mankhwalawa ayenera kugwiritsidwa ntchito pokhapokha ngati pali mabakiteriya omwe amayamba chifukwa cha mabakiteriya omwe amakhala ndi chidwi cha amoxicillin. Amoxiclav sikugwira ntchito motsutsana ndi ma virus. Njira yoyenera yoyambira yothandizira maantibayotiki ndikuchita kafukufuku wa bacteria, ndikuwonetsa chikhalidwe cha causative wothandizila wa pathological ndikuwonetsa chidwi chake ku Amoxiclav.
Ngati palibe zotsatira kuyambira pakuyamba kugwiritsa ntchito mapiritsi a Amoxiclav mkati mwa maola 48-72, amasinthidwa ndi mankhwala enanso othandizira kapena njira zochiritsira zosinthika zasintha.
Mosamala kwambiri, Amoxiclav amagwiritsidwa ntchito mwa odwala omwe ali ndi chiwindi kapena vuto la impso, pomwe ntchito zawo zimayang'aniridwa.
Panthawi ya mankhwala
Palibe chidziwitso pakuwonongeka kwa Amoxiclav pa mwana wosabadwayo. Komabe, kugwiritsa ntchito koyamba kwa nthawi ya mimba ndikosayenera. Pakumapeto kwakanthawi komanso poyamwitsa, mankhwalawa amavomerezedwa kuti agwiritsidwe ntchito, koma kuvomerezeka kuyenera kuchitika kokha moyang'aniridwa ndi dokotala.
Amoxiclav pamapiritsi a ana aang'ono sagwiritsidwa ntchito, popeza imakhala ndi zinthu zambiri zogwira ntchito, zopangidwira zaka zapakati pa 6.
Kugwiritsa ntchito pamodzi ndi mankhwala a magulu ena a mankhwala kuyenera kukhala osamala kwambiri. Osagwiritsa ntchito mankhwala omwe amachepetsa magazi ndikuwopsa kwa chiwindi kapena impso.
Mapiritsi a Amoxiclav samasokoneza kwenikweni momwe munthu amachitikira komanso kuwonongeka.

Malangizo onse apaderawa okhudza kugwiritsidwa ntchito kwa Amoxiclav amayenera kuganiziridwa ndi adokotala asanakumane.

Zotsatira zoyipa

Poyerekeza ndi kafukufuku wazachipatala ndi ndemanga za Amoxiclav 1000 mg, kugwiritsidwa ntchito kwake kumatha kubweretsa zotsatirazi:

Kutsegula m'mimba
Thupi la mkamwa wamkamwa,
Vaginal thrush,
Kuphwanya zam'mimba zam'mimba,
Zotupa pakhungu
Matupi a mziwambo,
Pseudomembranous colitis,
Mankhwala otupa chiwindi
Cholestatic jaundice (makamaka odwala okalamba).

Zonsezi pamwambapa ndizosowa kwambiri, izi sizowonjezera, koma zopanda pake. Kuwonjezeka kwa kuchuluka kwa magazi amomwe kumachitika pakatha masiku asanu ndi awiri.

Zotsatira zoyipa zambiri, makamaka zomwe zimagwirizanitsidwa ndi m'mimba, zitha kupewedwa mwa kutenga Linex (mabakiteriya amoyo) kapena ma probiotic ena nthawi yomweyo monga mankhwala omwe tikufotokozera.

Kuphatikizika, mawonekedwe ndi ma CD

Amoxiclav (1000 mg) imakhala ndi zinthu monga mchere wa potaziyamu wa clavulanic acid ndi amoxicillin trihydrate. Ikupezeka munthawi izi:

mapiritsi okhala ndi filimu
ufa woyimitsidwa
lyophilized ufa wa jakisoni.

Mapiritsi a Amoxiclav (1000 mg) ali ndi matuza a aluminium ndi mapaketi a makatoni, motsatana.

Mphamvu yakuyimitsidwa imapezeka m'mbale zagalasi zakuda. Komanso supuni yoyezera imaphatikizidwa ndi mankhwalawo.

Ponena za mawonekedwe a jakisoni, amapezeka m'mabotolo a 1.2 ndi 0,6 g, omwe amaikidwa m'mabhokisi a makatoni.

Zotsatira za pharmacological

Kodi mankhwala a Amoxiclav amagwira ntchito bwanji? Malangizo, ndemanga zimanena kuti kuphatikiza kwa clavulanic acid ndi amoxicillin ndiwopadera mu mtundu wake.

Amoxicillin amachititsa kufa kwa mabakiteriya pomangiriza kuzilimba zawo. Komabe, tizilombo tambiri tambiri taphunzira kuwononga maantibayotiki kudzera mu enzyme beta-lactamase. Zochita za enzymeyi zimatha kuchepetsa clavulanic acid. Chifukwa cha izi, kuyimitsidwa, jakisoni ndi mapiritsi a Amoxiclav (1000 mg) amagwiritsidwa ntchito pochiza matenda ambiri opatsirana.

Bongo

Kuchuluka kwazowonjezera za mankhwalawa mukamamwa mapiritsi a Amoxiclav kumatha kuyenda limodzi ndi kusintha kwa magwiridwe am'mimba ammimba (kusekera, kusanza, kutsekula m'mimba, kupweteka kwam'mimba), ndi mitsempha (mutu, kugona, kukokana). Nthawi zina bongo wambiri wa mankhwalawa ungayambitse hemolytic anemia, chiwindi kapena impso. Ngati muli ndi vuto la bongo, muyenera kusiya kumwa mankhwalawo ndi kupita kuchipatala. Mankhwalawa amagawidwa m'mafakisoni mwa mankhwala.

Gwiritsani ntchito panthawi yoyembekezera komanso poyamwitsa

Kafukufuku wazinyama sanawululire zowopsa za kumwa mankhwalawa panthawi yomwe ali ndi pakati komanso momwe zimakhudzira kukula kwa fetal.

Kafukufuku wina mwa azimayi omwe ali ndi matendawa asanakwane, zimapezeka kuti kugwiritsa ntchito prophylactic ndi amoxicillin / clavulanic acid kumatha kuphatikizidwa ndi chiopsezo chowonjezeka cha necrotizing enterocolitis mu akhanda. Pa nthawi yoyembekezera komanso mkaka wa m'mawere, mankhwalawa amagwiritsidwa ntchito pokhapokha ngati phindu lomwe limaperekedwa kwa mayi limaposa chiwopsezo cha mwana wosabadwayo ndi mwana. Amoxicillin ndi clavulanic acid ochepa omwe amalowa mkaka wa m'mawere. Mu makanda omwe amalandila yoyamwitsa, kukula kwa chidwi, kutsegula m'mimba, ma micidi a mucous nembanemba amkamwa amatha. Mukamamwa Amoxiclav 875 + 125, ndikofunikira kuthetsa nkhani yosiya kuyamwitsa.

Katundu wa mankhwala osokoneza bongo

Kodi maantibayotiki ali ndi zinthu ziti? Amoxiclav (1000 mg) amapha ngakhale mabakiteriya omwe asonyeza kale kukana kwa amoxicillin.

Mankhwala omwe amafunsidwa ali ndi tanthauzo la bactericidal ndi bacteriostatic pamitundu yonse ya echinococcus, streptococcus ndi listeria (kupatula michere yolimbana ndi methicillin). Komanso, mabakiteriya opanda gramu monga Brucella, Bordetella, Gardnerella, Salmonella, Klebsiella, Proteus, Moraxella, Clostridium, Shigella ndi ena amamvera mankhwalawa.

Pharmacokinetics

Kodi ndingatenge Amoxiclav (1000 mg) ndi chakudya? Mosasamala chakudya, mankhwalawa amatengedwa bwino kuchokera m'matumbo. Kuyika kwake kwakukulu kumafika patatha mphindi 60. Ili ndi kuthamanga kwambiri komanso kuchuluka kwa magawidwe m'thupi (m'matumbo, m'mapapu, mosakanikirana ndi m'madzi am'mimba, adipose ndi minofu minofu, gland ya prostate, khutu lapakati komanso sinuses).

Mu mkaka wa m'mawere, mankhwalawa amaperekedwa pang'ono.

Amoxicillin amawonongeka pang'ono mthupi, ndipo asidi wa clavulanic amakhala ndi mphamvu zambiri.

Mankhwalawa amathandizidwa kudzera mu impso, komanso mapapu ndi matumbo. Moyo wake theka ndi mphindi 90.

Amoxiclav: chimathandiza ndi chiyani?

Maantibayotiki omwe amafunsidwa kuti apatsidwe matenda osiyanasiyana opatsirana:

kupuma thirakiti (mwachitsanzo, sinusitis yayitali kapena pachimake), kutupa kwa khutu lapakati, pharyngeal abscess, tonsilopharyngitis, bronchitis, chibayo ndi ena,
matenda a gynecological (kuchotsa septic, endometritis, salpingitis, etc.),
kwamkodzo thirakiti (pyelonephritis, cystitis, urethritis, etc.),
matenda a mafupa
matenda a odontogenic, momwe tizilomboti timalowa m'thupi la munthu kudzera m'miyendo m'mano,
matenda amtundu (gonorrhea, chancroid),
matenda okhudzana ndi minofu
kutupa kwa biliary thirakiti (mwachitsanzo, cholecystitis, cholangitis),
matenda a pakhungu, komanso minofu yofewa (phlegmon, kuluma, matenda a bala).

Mankhwala "Amoxiclav": Mlingo ndi njira zogwiritsira ntchito

Mankhwala "Amoxiclav" amatha kuperekedwa kwa odwala m'njira zosiyanasiyana. Njira yogwiritsira ntchito matendawa imatengera kulemera ndi zaka za wodwalayo, momwe chiwindi ndi impso zimayambira, komanso kuopsa kwa matendawa.

Nthawi yabwino yogwiritsira ntchito mankhwalawa ndikuyambira kudya. Kutalika kwa mankhwala ndi mankhwalawa ndi masiku 6-14. Sizoletsedwa kugwiritsa ntchito mankhwalawa nthawi yayitali kuposa nthawi yokhazikika.

Kwa ana ochepera zaka 12, mankhwala opha mabakiteriya amawaikira pa 40 mg pa kilogalamu ya thupi patsiku. Achinyamata omwe akulemera kuposa makilogalamu 40 amapatsidwa mankhwalawa muyezo womwewo wa akulu.

Akuluakulu, mapiritsi 375 mg amadziwika maola 8 aliwonse, ndipo 625 mg maola 12 aliwonse. Kwa matenda oopsa, wodwalayo amalangizidwa kuti amwe mankhwala pa 625 mg (maola 8 aliwonse) kapena 1000 mg (maola 12 aliwonse).

Madokotala agogomezera kuti mapiritsi a Amoxiclav amatha kusiyanasiyana ndi kuchuluka kwa zosakaniza zomwe zimagwira. Chifukwa chake, ziyenera kukumbukiridwa kuti ndizoletsedwa kulowa m'malo a 625 mg ndi awiri a 375 mg.

Zochizira matenda opatsirana a odontogenic, njira yotsatirayi imagwiritsidwa ntchito: mankhwala pa mlingo wa 375 mg amadziwika maola 8 aliwonse, komanso pamankhwala a 625 mg maola 12 aliwonse.

Ngati mukufuna kumwa mankhwala kwa odwala omwe ali ndi matenda a impso, ndiye kuti mkodzo wa creatinine uyenera kukumbukiridwa. Mwa anthu omwe ali ndi matenda a chiwindi, kuyang'anira ntchito yake nthawi zonse kuyenera kuchitika.

Kodi amoxiclav iyenera kuperekedwa bwanji kwa ana aang'ono? Kuyimitsidwa, mtengo wake womwe sunakhale wokwera kwambiri, umaperekedwa kwa ana mpaka miyezi itatu. Mlingo wa mankhwalawa umatsimikiziridwa pogwiritsa ntchito supuni kapena pipette. Pa kilogalamu iliyonse ya kulemera kwa mwana, 30 mg ya amoxicillin ayenera kuperekedwa. Imwani mankhwalawa kawiri pa tsiku.

Kwa ana opitilira miyezi itatu ndi pafupifupi komanso ofatsa matendawa, mankhwalawa amadziwitsidwa pa 20 mg pa kilogalamu yolemera.

Kodi Amoxiclav amagwiritsidwa ntchito bwanji pa matenda oopsa? Kuyimitsidwa (mtengo wa mankhwalawo udzawonetsedwa pansipa) umaperekedwa kwa ana omwe ali ndi 40 mg pa kilogalamu yolemera. Mlingo womwewo umagwiritsidwa ntchito pochiza matenda akuya (mwachitsanzo, ndi kutupa kwamkati, bronchitis, sinusitis, chibayo, etc.).

Mlingo wambiri watsiku ndi tsiku wa amoxicillin wa ana ndi 45 mg / kg, ndi akulu - 6 magalamu. Nkhani ya clavulanic acid, imatha kutengedwa patsiku osaposa 10 mg / kg kwa ana ndi 600 mg kwa akuluakulu.

Zotsatira zoyipa

Monga lamulo, Amoxiclav imalekeredwa bwino. Ngakhale nthawi zina, zovuta zimachitika mwa achikulire komanso odwala omwe amamwa mankhwalawo kwa nthawi yayitali.

Nthawi zambiri, zinthu zoyipa zimachitika pakumala kapena kumaliza ntchito. Ngakhale nthawi zina chitukuko chimawonedwa pakatha milungu ingapo mutalandira chithandizo:

kutsegula m'mimba, kusefukira kwamkati, nseru, glossitis, kusanza, pseudomembranous colitis, dyspepsia, stomatitis, kusinthasintha kwa lilime, gastritis, enterocolitis,
kuchepa kwa magazi m'thupi (hemolytic), agranulocytosis, eosinophilia, kuchepa kwa kuchuluka kwa ma cell ndi leukocytes,
chizungulire, kupweteka mutu, kusayenera, kukwiya, kusowa tulo, kukomoka,
kuchuluka kwa mayesero a chiwindi, kuchuluka kwa asymptomatic mu ntchito ya AsAT, zamchere phosphatase ndi AlAT, komanso kuchuluka kwa bilirubin m'magazi
zotupa, erythema multiforme, urticaria, exfoliative dermatitis, angioedema, Stevens-Johnson syndrome, poyizoni epermermal necrolysis,
magazi mkodzo, interphitial nephritis,
candidi pamlomo, malungo, feminitis yodziwika bwino (ndikugwiritsa ntchito mankhwalawa kwa nthawi yayitali).

Zofananira zina za mankhwala

Ndikosayenera kuphatikiza Amoxiclav ndi anticoagulants osadziwika, chifukwa izi zimatha kuwonjezera kuchuluka kwa prothrombin nthawi.

Mankhwala omwe akufunsidwa amathandizira kuwopsa kwa Metatrexate.

Kuchita kwa allopurinol ndi Amoxiclav kumayambitsa chiopsezo cha exanthema.

Sizoletsedwa kupereka mankhwala okhala ndi macrolides kapena tetracyclines, komanso sulfonamides chifukwa kuchepa kwake.

Simungathe kuphatikiza rifampicin ndi amoxicillin, popeza awa ndi othandizira. Kuphatikiza kwawo pamodzi kumafooketsa mphamvu ya antibacterial yonse.

Kumwa mankhwala omwe mukufunsidwa kumachepetsa mphamvu yolerera pakamwa.

Tiyeneranso kudziwa kuti mankhwalawa "Amoxiclav" (1000) ndi mowa amaletsedwa kuphatikiza chifukwa cha kuchuluka komwe kungachitike poyipa.

Mtengo, matchulidwe ndi ma fanizo

Mgwirizano wa mankhwalawa ndi: "Clavocin", "Augmentin" ndi "Moksiklav." Ponena za fanizo, ndiye kuti:

Kodi mankhwala a Amoxiclav ndi angati? Mtengo wake umatengera mtundu wa kumasulidwa. Mapiritsi (1000 mg) atha kugulika ma ruble 480, kuyimitsidwa kwa 280, ndi lyophilized ufa wovulaza kwa 180.

Ndemanga za Mankhwala

Malinga ndi kuwunika kwa odwala, mankhwalawa ndi mankhwala othandiza omwe amagwiritsidwa ntchito pochiza matenda ambiri opatsirana. Mukamamwa mankhwala othandizira odwala kupuma, mpumulo umabwera tsiku lachitatu.

Komanso, mankhwalawa amathandizira pochizira matenda a genitourinary.

Kuphatikiza pa ndemanga zabwino za antibayotiki, odwala amasiya mauthenga olakwika. Malinga ndi iwo, mankhwalawa "Amoksiklav" amayambitsa mavuto ambiri, omwe amawonetsedwa ndi mseru, m'mimba komanso kusanza.

Mtengo wa Amoxiclav 1000 ndi mawonekedwe ake

Mtengo wa Amoxiclav 1000 mg ndi ma ruble pafupifupi 440-480 phukusi lomwe limakhala ndi matuza awiri, chilichonse chili ndi mapiritsi 7. Mtengowu umachitika chifukwa cha ntchito yaku Swiss komanso ndalama zolipirira zomwe zimayendera. Amoxiclav opangidwa ku Germany atenga pafupifupi ma ruble 650. Zofanizira zapakhomo ndizotsika mtengo, koma osati zochuluka, Augmentin 1000 mg yofananira ndi ndalama pafupifupi ma ruble 300. Uku ndiye mtengo wa mankhwala othana ndi antibayotiki.

Kuchita ndi mankhwala ena

Mankhwala omwe amateteza katulutsidwe ka tubular kumawonjezera ndende ya amoxicillin. Ndi munthawi yomweyo makonzedwe a Amoxiclav ndi glucosamine ndi maantacid okhala, mankhwala ofewetsa thukuta, mayamwidwe amachepetsa. Ngati mumamwa Amoxiclav ndi ascorbic acid nthawi imodzi, mayamwidwe, m'malo mwake, adzakuthandizani.

Irina F., wazaka 39. Therapist “Mankhwala ochepetsa mphamvu ya antibayotiki, wogwira ntchito pamatenda ambiri osavuta am'mapapo. Kuopsa kochepa. Ndi makonzedwe a munthawi yomweyo ndi Linex kapena ma proiotic ena, sizimayambitsa kusokonezeka kwa m'mimba thirakiti. Zotsatira zakuchipatala ndizothamanga kwambiri. "

Karina S. wazaka 23. Accountant “Adatenga mankhwala awa ku mavuto a impso. Pamene mkodzo unayamba kuda, ndimatope, ndinazindikira popanda dokotala kuti panali matenda. Chidatengera malangizo ogwiritsa ntchito. Chilichonse chopita mwachangu, mkodzo ndi wabwinobwino - umatha kuwonekera popanda kuwunika. ”

Larisa M., wa zaka 44. Ogulitsa "Ndikofunika kuti musamwe mankhwalawa ngati pakadutsa miyezi itatu chichitikireni chithandizo chomaliza. Ndinaphunzira izi kuchokera kwa dotolo pomwe ndimadzipanga nokha sinusitis, koma sizinathandize. Chifukwa izi zisanachitike Amoksiklav ankachitira impso. Ngati pakadatha miyezi itatu chichitikireni chithandizo chomaliza, sinthani maantibayotiki. ”

Kodi Amoxiclav ndi chiyani? Kodi mankhwalawa amathandizira nawo chiyani? Muphunzira mayankho a mafunso amenewa ndi mafunso ena kuchokera pazinthu zomwe zalembedwa. Tikukuwuzani za kuchuluka kwa mankhwalawa, momwe amapangidwira komanso ngati angaphatikizidwe ndi mowa.

Madokotala amafufuza

Anna Leonidovna, wothandizira, Vitebsk. Amoxiclav imakhala yothandiza kwambiri pochiza matenda osiyanasiyana opuma kuposa momwe analogue, amoxicillin. Ndikupereka maphunzirowa masiku 5, kenako ndikofunikira kumwa mankhwala omwe amakonzanso microflora.

Veronika Pavlovna, dotolo. Mr. Kreshyi Rih. Mankhwalawa ali ndi vuto labwino kwambiri pakulimbana ndi bakiteriya a kumaliseche. Sichimaperekanso zovuta, nthawi yomweyo ndimapereka mankhwala a antifungal, nditatha kumwa ma probiotic kuti ndikonzenso microflora yachilendo.

Andrei Evgenievich, dotolo wa ENT, Polotsk. Kugwiritsa ntchito mankhwalawa jekeseni kumakuthandizani kuti muchepetse kuwonetsa kwa matenda oopsa komanso olimbitsa a ziwalo za ENT. Mankhwala amathandizira kutukusira khutu lapakati. Kuphatikiza apo, odwala amatenga bwino kuyimitsidwa kwa zipatso.

Ndemanga za Odwala

Victoria, Dnipropetrovsk. Kugwiritsidwa ntchito ndi adokotala pochiza matenda a tonsillitis. Anaona masiku 5. Mankhwala olimbana ndi mankhwalawa adayamba patsiku la 3 la matenda. Matendawa adachepetsa ndi wachitatu. Khosi langa linasiya kuwawa. Zinali

, adadutsa masiku awiri, atayamba kutenga ma probiotic kuti abwezeretse microflora.

Alexandra, mzinda wa Lugansk. Mankhwalawa adalembedwa ndi dokotala kuti azichiza pyelonephritis. Maphunzirowa anali masiku 7. Jekeseni wa masiku atatu - kenaka mapiritsi. Jakisoni amakhala wowawa. Komabe, kusintha kunayamba mozungulira tsiku lachinayi. Panalibe mavuto. Ndiye kamwa youma ija.

Tamara, mzinda wa Boyarka. Adandilowetsa mankhwalawa ngati mankhwalawa. Zimakhala zopweteka kwambiri, mikwingwirima idatsalira pamalo a jakisoni. Komabe, patatha sabata limodzi palibe chomwe chatsalira mu smears kuchokera kwa pathogen.

Amoxiclav ya ana

Lilia Evgenievna, Saransk. Amoxiclav (kuyimitsidwa) anathandizira chibayo mwa mwana wathu. Ali ndi zaka 3.5. Patsiku lachitatu, matumbo atayamba, dokotala adapereka mankhwala omwe amamwa atatha maphunzirowo kwa mwezi wina. Kutupa kwamapapu kunagonjetsedwa mwachangu - pa 10, mwana anali kale kumva bwino. Momwe ndikumvera, maantibayotiki onse ayenera kutsukidwa ndi kukonzekera kwa bakiteriya.

Ngati mankhwalawa amagwiritsidwa ntchito kwanthawi yayitali, ndikofunikira kuyang'anira ntchito ya chiwindi, ziwalo zopanga magazi ndi impso za wodwalayo. Ngati wodwalayo wasokoneza ntchito yaimpso, ndikofunikira kusintha mlingo kapena kuonjezera pakadali pakati Mlingo wa mankhwala. Ndikwabwino kumwa mankhwala ndi chakudya. Pankhani ya superinfection (mawonekedwe a microflora osazindikira maantibayotiki), ndikofunikira kusintha mankhwalawa. Chifukwa chakuchulukana kwa matupi a cephalosporins mwa odwala omwe ali ndi penicillin, sikofunikira kugwiritsa ntchito maantibayotiki nthawi imodzi.

Mukamamwa mankhwalawa, muyenera kumwa madzi ambiri kuti mupewe mapangidwe amkodzo wa amoxicillin.

Mukuyenera kudziwa kuti kupezeka kwa Mlingo wambiri wa maantibayotiki mthupi kumatha kupangitsa kuti shuga azigwirizana ndi mkodzo (ngati malingaliro a Benedict kapena njira ya Fleming agwiritsidwa ntchito kuti adziwe). Zotsatira zodalirika pamenepa zimapereka ntchito ya enzymatic reaction ndi glucosidase.

Popeza zotsatira zoyipa za m'magazi amanjenje ndizotheka kugwiritsa ntchito mankhwalawa, ndikofunikira kuyendetsa bwino magalimoto (magalimoto) kapena kuchita zinthu zomwe zimafunikira chidwi, kuthamanga ndi chidwi.

Amamasulidwa pa mankhwala.

Kutulutsa Fomu	Mtengo mu Russian Federation	Mtengo ku Ukraine
Kuyimitsidwa kwa	280 rub	42 UAH
Mapiritsi 625	370 RUB	68 UAH
Ampoules 600 mg	180 rub	25 UAH
Amoxiclav Quicktab 625	404 rub	55 UAH
Mapiritsi a 1000	440-480 rub.	90 UAH

Zosungirako ndi moyo wa alumali Sitolo m'malo ouma osawonekera kwa ana. Kutentha kosungira - osaposa 25 digiri. Kugwiritsa ntchito mankhwalawa atatha nthawi yawo yoletsedwa.

CHIYAMBI! Zomwe zidatumizidwa patsamba lathu ndizothandiza kapena ndizotchuka ndipo zimaperekedwa kwa omvera ambiri kuti azikambirana. Chithandizo cha mankhwala chikuyenera kuchitika kokha ndi katswiri woyenera, kutengera mbiri yachipatala ndi zotsatira za matenda.

Lek dd, Slovenia
Moyo wa alumali: mpaka 01.05.2019

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