Glucophage 850: mtengo wa mapiritsi, ndemanga ndi malangizo

Glucophage 850 ndi mankhwala a hypoglycemic otengera metformin, omwe amachepetsa hyperglycemia ndipo samatsogolera ku hypoglycemia.

Chithandizo chachikulu ndikuchiza matenda a shuga. Kuphatikiza apo, ndi njira yothandiza yolimbana ndi kunenepa kwambiri. Wopanga amatulutsa mankhwalawo ngati mapiritsi.

Glucophage 850 - malangizo angagwiritsidwe ntchito

Zisonyezo zakumwa mankhwalawa:

• Type 2 shuga mellitus, ngati kuchepa kwa chakudya chamagulu komanso kuwonjezereka kwa zolimbitsa thupi sikunathandize, makamaka kwa iwo omwe ali onenepa kwambiri.

Zoyipa:

• Kusalolera kwa aliyense pamaderamo,
• Matenda ashuga ketoacidosis, precoma kapena chikomokere,
• Matenda a mtima
• Mimba, komanso nthawi yoyamwitsa.
• Mowa
• Ngati pali vuto ndi impso.
• Zolakwika mu chiwindi,
• Nthawi zisanafike,
• Mliri
• Ana osakwana zaka 10
• Odwala omwe ali ndi matenda a shuga 1.

Anthu opitilira 60 ayenera kugwiritsa ntchito mapiritsiwa mosamala kwambiri. Komanso amene amagwira ntchito zolimbitsa thupi.

Chithandizo:

• M'masiku oyamba kukonzekera, mlingo waukulu ndi 1000 mg ya mankhwalawa.
• Kuphatikiza apo, pakalibe zovuta, pakatha masiku 10-15, mlingo wa tsiku ndi tsiku ungathe kuwonjezeredwa kamodzi ndi theka mpaka kawiri.

Momwe mungagwiritsire ntchito Glucofage 850 pakuchepetsa thupi?

• Mankhwala tikulimbikitsidwa kuti amwe musanadye kapena nthawi ya chakudya.
• Mlingo wapamwamba wa tsiku ndi tsiku ndi 3000 mg, ndiye kuti, uyenera kugawidwa m'magawo atatu.
• Piritsi sikufunikira kutafunidwa, kumeza lonse, kutsukidwa ndi madzi.
• Kutalika kwa ntchito mpaka masiku 22.

Popeza kudya nthawi yayitali kumapangitsa kuti thupi lizisokoneza komanso kuchepa kwa ntchito. Ngati zotsatira zake sizikwaniritsidwa, mutha kubwereza m'miyezi iwiri.

Zotsatira zoyipa

Ngati mumatsatira mankhwalawo, zoyipa sizowonedwa. Ngati muli, ndiye kuti muyenera kuchepetsa mlingo.

Zotsatira zoyipa izi zitha kuchitika:

• Kuyabwa
• Kutupa.
• Mutu.
• Kuphwanya kukoma.
• Kusanza, kusanza, kutsegula m'mimba, kusowa chilakolako cha chakudya.
• Kuwonongeka kwa chiwindi ntchito chiwindi.
• Lactic acidosis.

Malangizo apadera nthawi zina

1. Osowa kwambiri, lactic acidosis imatha kuchitika - kuphatikiza kwakukulu kwa metabolic, chifukwa chotsatira cha metformin hydrochloride. Imatha kudziwoneka ngati minofu kukokana, kumva kupweteka m'mimba, kufupika, ndi hypothermia. Coma akhoza kubwera pambuyo pake. Ngati mukukayikira kuti lactic acidosis, muyenera kusiya kutenga ndikupita kuchipatala.
2. Chenjezo pa opaleshoni. Ngati wodwala agwiritsa ntchito mankhwalawa, ndiye kuti awiri asanachite opareshoni, ayenera kusiya kuigwiritsa ntchito. Ndipo mutha kuyambiranso kuziona pambuyo poona ntchito ya impso, osapitirira masiku awiri pambuyo pake.
3. Chenjezo pakulephera kwa impso. Ngati odwala asokoneza ntchito yaimpso, ndiye kuti plasma creatinine iyenera kuyang'aniridwa. Zomwezo zitha kulimbikitsidwa kwa anthu achikulire.
4. Ngati odwala akuyenera kuphunzira mankhwala a radiopaque omwe amakhala ndi ayodini, muyenera kusiya kumwa Glucofage masiku 850 pamaso pawo. Ndi kuyambiranso patatha masiku awiri, koma mutatha kuwunika, maloboti a impso.

Glucophage ndi zakudya

Kumwa mankhwalawa kuyenera kusungidwa ndi kudya pang'ono kwa chakudya chambiri. Ndikofunikira kutsatira zakudya zama calorie otsika ndikuwongolera glucose osalephera.

Mphamvu yothetsa mapiritsiwo imakulimbikitsidwa ngati simuphatikiza zakudya zamagulu olimbitsa thupi zomwe zimawononga zochita za metformin mthupi. Mwa zina: shuga, mitundu yonse ya maswiti, masikono, nthochi ndi mphesa.

Malonda oletsedwa:

• Shuga
• Zopangira
• Chocolate ndi maswiti
• Zakumwa za kaboni
• Zipatso zouma.

Zosafunika:

• Pasitala.
• Mpunga Woyera
• Mbatata.
• Phula yokhazikika.

Pazakudya muyenera kuwonjezera zakudya zomwe zimakhala ndi CHIKWANGWANI:

• Ziphuphu.
• Masamba.
• Mkate wa ndani.

Komanso muyenera kuwonjezera zolimbitsa thupi. Izi zingathandize kuthamangitsa kunenepa.

Ndemanga za madotolo za kutenga "Glucofage" pofuna kuchepetsa thupi

Chipangizocho chikuyenera kuperekedwa ndi dokotala pambuyo pakuwunika. Ili ndi zovuta zingapo zoyipa zomwe zimakhala zowononga thanzi.

Kafukufuku wambiri wachitika omwe akuwonetsa kuti iyo yokha siyimachepetsa thupi. Izi, mwina, zimachitika chifukwa cha chithandizo cha vuto lalikulu - matenda ashuga, popeza mankhwalawa amathana bwino ndi kuchepa kwa shuga. Palibe chifukwa chomwa mankhwala ngati kunenepa kumalumikizidwa ndi ulesi ndi kususuka, sizimveka ndipo zimakhala zowopsa.

Mukamamwa mankhwala ena, muyenera kufunsa dokotala.

Ndemanga za kuchepetsa kunenepa

Malingaliro a anthu omwe amamwa mankhwalawa ndiosiyana kwambiri. Ngati mankhwalawo adayamba kugwiritsidwa ntchito popanda zikuwonetsedwa ndi anthu omwe akudwala matenda ashuga, momwe thupi limayendera limatha kukhala losatsimikizika.

Choyipa chachikulu, ngati munthu azisankha yekha payekha. Kuti pasakhale zovuta zina, mukufunikirabe kufunsa katswiri woyenera musanayambe chithandizo.

Magulu a Glucophage 850:

1. Elena: "Pakupita mwezi umodzi, adataya makilogalamu 7 popanda zovuta zilizonse. Dziwani kuti madokotala ku Europe nthawi zambiri amagwiritsa ntchito ovary ya polycystic. ”
2. Eugene: "Ndine wachiwiri matenda ashuga, adandipatsa mankhwala. Ndinkamwa mapiritsi kawiri patsiku, ndimatha kutaya makilogalamu 6.5 m'miyezi iwiri yokha. Ngakhale sanayesetse kuchita izi, anali ndi moyo wabwino. ”
3. Zinaida Petrovna: “Ndinkamwa chifukwa chachipatala, sindinadye. Panthawi yamankhwala, sanachepetse thupi. Pazakudya, kwenikweni, ndachepa, koma sindingathe kunena kuti mankhwalawa ndi abwino. ”
4. Maria: "Sindinapezeke ndi matenda a shuga, koma shuga ndiwambiri ngati ndilola kudya kwambiri, komanso kunenepa kwambiri. Ntchito njira zambiri kuti muchepetse kunenepa. Ndinafika poti chikhodzodzo changa chimachotsedwa ndikamadya zakudya zama protein. Nditayamba kumwa mankhwalawa, ndidatha kuchotsa ma kilogalamu asanu pamwezi umodzi. ”
5. Christina: “Ndimagwiritsa ntchito mankhwalawa kawiri patsiku. Makhalidwe achikunja asintha. Sichikukokeranso ku zakudya zamchere monga kale komanso chakudya. Ndimamva kukoma kosasangalatsa mkamwa mwanga, ndipo zimandidwalitsanso nthawi zina. Chifukwa chake, adayamba kudya zakudya zochepa, chifukwa kulakalaka sikofanana. Ndimamva pakamwa lowuma ndikumwa madzi ambiri. Ziphuphu zimachepa kumaso, ngakhale kuti pigmentation yaying'ono idawonekera. Mwambiri, ndimakhutira ndi zomwe zimachitika, chifukwa kulemera kumachoka. "
6. Maria Valerevna: Uku ndiye kuchiritsa matenda a shuga! Ndipo izi siziyenera kuyiwalika. Dokotala adandilembera ine, atakhazikitsa kale matendawa. Inde, ndataya zoposa ma kilogalamu khumi ndi Glucofage, koma chinthu chachikulu kwa ine ndikuti amakhala ndi shuga, osatero ayi. ”
7. Elena: “Ndimamwa mankhwalawa polimbana ndi matendawa. Sindinaganizirepo zakuti zithandiza kuonda. Kulemera kwanga kukuwonjezeka kwambiri chaka chatha. Ndipo motsutsana ndi zoyambira kutenga Glucofage 850 ndipo, kutsatira zakudya zamafuta, ndidachotsa mapaundi owonjezera asanu ndi anayi. Zaumoyo wokhudzidwa, zimayenda bwino. Komabe, chinthu chofunikira kwambiri kwa ine ndikuti mankhwalawa amasunga shuga wanga bwinobwino. ”

Glucophage kanthu kwa kuwonda

Kunenepa kwambiri kumadziwika chifukwa cha kuchuluka kwa magazi ndi shuga. Mankhwala omwe afunsidwa ali ndi mphamvu yakutsitsa. Kuphatikiza apo, kumwa mankhwalawo sikulola kuti mafuta azikhala ndi mpweya, shuga m'chiwindi amawapanga ndikupanga makhoma am'mimba. Zakudya zowonjezera zonse za thupi zimangotuluka ndi chopondacho.

Kodi Glucophage 850 imakuthandizani kuti muchepetse kunenepa?

Mankhwalawa amateteza njira zonse za metabolic, m'mimba mwa wodwala, amachepetsa kupanga shuga ndi insulin, zomwe zimalepheretsa kuchuluka kwa mafuta m'thupi.

Chidacho chimachepetsa chilakolako chofuna kudya, komanso kulakalaka maswiti, zomwe zimathandizanso kuchepetsa kunenepa. Zotsatira zake, munthu samadya kwambiri, motero, insulin simalowa m'magazi.

Ubwino wa Glucophage ndikuti zimakhala ndi zovuta zochepa.

Mitengo ya Glucophage m'masitolo ogulitsa mankhwala ku Moscow

Madokotala amawunika za glucophage

Amachepetsa shuga m'magazi popanda kuchititsa hypoglycemia, kumenyana ndi insulin, kumakhudza metabolidi ya lipid, amachepetsa kuyamwa kwa m'matumbo ndikuthandizira kuchepetsa thupi, zomwe ndizofunikira kwambiri kwa odwala omwe ali ndi metabolic syndrome komanso kunenepa kwambiri.

Odwala amafotokoza zovuta za mseru, matenda am'mimba. Potengera maziko a kumwa mankhwalawa, chiwindi ndi impso zimafunikira.

Mulingo wa golide pochiza osati mtundu wachiwiri wa shuga, komanso prediabetes. Ndi kugwiritsa ntchito pafupipafupi kwa odwala, osati kuchuluka kwa shuga wamagazi kokha komwe kumachepetsedwa, komanso kulemera kwa thupi. Kuopsa kwa hypoglycemia kumakhala kotsika.

Nthawi zonse muziwerengera GFR musanapereke mankhwala. Ndi gawo 4 CKD, mankhwalawa sawonetsedwa.

Mankhwala enieni ndi othandizadi ndipo amakhala ndi zotsika zina zoyipa akapatsidwa mankhwala moyenera. Mitundu yambiri ya ntchito ndi yotakata, kuyambira kulemera kambiri, mtundu wachiwiri wa matenda ashuga, kutsutsana ndi insulin m'matenda ena, kumatha pokonzekera ma ART, odwala PCOS, muzochita za ana, komanso mankhwala othandizira odwala zaka. Amasankhidwa pokhapokha atakakumana ndi katswiri. Mtengo wololera.

Mankhwala abwino kwambiri. Ndimagwiritsa ntchito, moyenera, m'njira zina zochepetsera kubereka kwa amuna omwe ali ndi hyperglycemia komanso kunenepa kwambiri. Ubwino wake ndi kuti ukagwiritsidwa ntchito, sayambitsa hypoglycemia.

Zosagwirizana ndi mowa, zomwe zimakhala ndi ayodini. Chenjezo liyenera kugwiritsidwa ntchito ngati vuto laimpso likuwonekera.

Itha kufotokozedwa mu zovuta zovuta zothandizira kubereka kwa abambo ndi andrologist monga momwe amagwirizana ndi endocrinologist.

Ndimagwiritsa ntchito mankhwalawa mankhwalawa matenda a matenda ashuga a 2, onenepa kwambiri. Thandizani kuchepa thupi popanda kuwononga thanzi lanu, kuletsa kukalamba kwa thupi. Mphamvu yaukatswiri yamankhwala imatsimikiziridwa. Mtengo wotsika mtengo wa mankhwalawo.

Mankhwala ogwira ndi kutsimikiziridwa.

Mankhwala oyamba kwambiri pamtengo wotsika mtengo. Amakonda kuchepa thupi.

Matenda am'mimba.

Mankhwala osokoneza bongo. Mankhwala okhala ndi mbiri yayitali, ogulitsidwa m'maiko ambiri padziko lapansi. Pochita zachipatala, ndimagwiritsa ntchito mankhwalawa. Ntchito mankhwalawa onenepa kwambiri.

Nkhondo yolimbana ndi insulin, kusowa kwa hypoglycemia, mwayi wogwiritsa ntchito osati matenda ashuga okha. Sizimayambitsa kufooka kwa cell ya beta.

Odwala ena amati amamwa m'mimba akamamwa mankhwalawa.

Mankhwala apadera okhala ndi mbiri yayitali, zotsatira zabwino osati kokha pakuchepetsa shuga, komanso kulemera.

Muzochita zanga zamankhwala, ndimapereka mankhwala a Glucophage kwa odwala omwe ali ndi matenda osokoneza bongo, kuphatikizapo odwala omwe ali ndi kunenepa kwambiri. Amachepetsa kuchuluka kwa shuga wopangidwa ndi chiwindi, komanso amachepetsa kuyamwa ndi matumbo. Kuchulukitsa kagayidwe kachakudya kwa odwala, kumathandizira kuchepetsa kunenepa kwambiri. Zotsatira zoyipa ndizogwiritsidwa ntchito moyenera sizigwirizana.

Mankhwala oyamba kwambiri pamtengo wotsika mtengo. Amakonda kuchepa thupi.

Matenda am'mimba.

Mankhwala othandiza kwambiri, muyezo wa "golide" wa matenda a shuga a 2. Sichimayambitsa hypoglycemia. Kuphatikizidwa ndi chithandizo cha kunenepa kwambiri. Kuvomerezedwa kuti mugwiritse ntchito muubwana.

Kugwiritsa ntchito osati kwa matenda ashuga okha.

Zosagwirizana ndi mowa. Kudya zakudya zopatsa mphamvu kumapangitsa kuti pakhale chopondapo.

Mankhwala apadera amtsogolo. Kafukufuku wamakono awonetsa kuthekera kwakukulu kwa mankhwalawa kutalikitsa moyo wa munthu. Amachepetsa mwayi wokhala ndi matenda ambiri a oncological ndipo amagwiritsidwa ntchito pochotsa kunenepa kwambiri.

Maganizo a odwala a Glucophage

Ndinayamba kutenga Glucophage ndipo ndinamva bwino. Amachepetsa shuga ndipo kunenepa kwambiri kumandisiya pang'onopang'ono. Ingotengani muyenera kuwonjezera pang'onopang'ono mlingo. Poyamba, ndidatenga 250 mg kwa masiku 10, kenako ndikusinthidwa kukhala 500 mg, ndipo tsopano ndimatenga 1000 mg.

Chimodzi mwa mankhwala abwino kwambiri kwa ine pa metformin. Ndimakonda zotsika mtengo, zoyenera komanso zoyambirira. Atatengedwa, adachepetsa shuga. Panalibe zotsatirapo zoyipa, monga zimakhalira ndi ma genetic. Ndipo mtengo wake ndi wokwanira.

Ndimamwa Glucophage nditapezeka ndi mtundu wachiwiri wa matenda a shuga. Nditamwa mankhwala ena omwe amachokera pa metformin, panali kudzimbidwa, koma Glucofage sizinadzetse zotsatirapo zilizonse, motero ndidaganiza kuti ndizimwa pambuyo pake. Miyezi isanu ndi umodzi yadutsa - mayeso ndi abwinobwino, ndikumva bwino. Ndipo adatha kuchepetsa thupi moyenera panthawiyi: pafupifupi 15 kg. The endocrinologist adaonjezera maphunziro anga kwa miyezi ina iwiri. Panthawi imeneyi, ndidzataya kilogalamu yowonjezera yomaliza.

Pomwe, malinga ndi zotsatira za mayeso, adapeza kuchuluka kwa shuga m'magazi, adawopa kwambiri shuga. The endocrinologist adalamula kudya kwapadera ndi kusamala kwambiri shuga, kuphatikizapo Glucofage. Mlingo anali osachepera 500 mg. 2 kawiri pa tsiku, mwezi umodzi pambuyo pake idakwera mpaka 1000x2. Kwa miyezi itatu, shuga adatsikira kumalire otsika ndipo pamakala anali opanda 7 kg). Ndikumva bwino tsopano.

Tsiku labwino kwa onse owerenga ndemanga zanga! Ndi mankhwala "Glucophage" akudziwika posachedwa. Poyamba sindinkakhala ndi mavuto azaumoyo, koma posachedwa, katswiri wa endocrinologist wandipatsa shuga ndikuwuza Glucophage kuti achepetse shuga. Mayi anga ankadwala matenda ashuga moyo wawo wonse, motero kudziwa kumeneku sikunadabwe kwambiri. Matenda a shuga si shuga pano, koma pali zofunika kale, ndipo ngati simukugwirizana ndi thanzi lanu, ndiye kuti matenda a shuga sakhala patali. Ndinayamba kumwa piritsi limodzi la "Glucophage" 1 madzulo. Poyamba, ndinkaopa kuti mavuto aliwonse amtundu wa m'mimba angayambike, koma sizinachitike ngati izi. Glucophage adandilandira bwino komanso adandichitira zabwino. Kugona komanso kumangokhala wotopa kumatha, mphamvu zambiri zinayamba, ndipo ngakhale kusinthasintha kunasiya kudumpha, ngati kale. Pang'onopang'ono, kuchuluka kwa "Glucophage" ndi dokotala kunakulitsidwa. Kuyambira 500 mg, tinasinthira ku 1000 mg. Kenako mumayenera kumwa 2000 mg patsiku. Kuchulukitsa mlingo wa Glucofage sizinawononge thanzi langa. Dotolo adandiuza kuti ndilandire miyezi itatu. Tsopano ndikupitiliza kutenga Glucophage. Mapiritsiwo ndi akulu mokwanira ndipo nthawi zina zimakhala zovuta kumeza. Ayeneranso kutsukidwa ndi madzi ambiri. Koma chofunikira kwambiri ndikuti amenya shuga bwino. Ndipo pali chinthu chimodzi chofunikira cha Glucophage, makamaka kwa anthu onenepa kwambiri. Mankhwala othandizira a Glucophage, metformin, amathandizira kuchepetsa thupi. Ndimamva momwe zimandikhudzira. Panthawi yomwe ndimatenga Glucophage, ndidataya makilogalamu 12.Tsopano ndili bwino kwambiri ndipo sindimvekanso ngati mayi wamkulu wopanda mawonekedwe)) Kulemeraku sikunawonekere kwa ine, ndipo tsopano ndinasinthiratu zovala zanga. Tsopano kulemera kwayima, mwachionekere, zonse zomwe ndimafuna, ndidataya kale. Metformin imalepheretsa kupezeka kwa chakudya chamthupi ndipo imasintha kagayidwe m'thupi. Chifukwa cha katunduyu, mapaundi onse owonjezera amapita. Koma sindingalangize kutenga Glucophage kwa anthu onenepa kwambiri popanda kuyang'aniridwa ndi dokotala. Ndikuganiza kuti mankhwala aliwonse amafunika kuyang'anira akatswiri.

Amakakamizidwa kumwa mankhwalawa pa metformin chifukwa cha matenda a shuga a 2. Koma mankhwalawa ndiabwino: akagwiritsidwa ntchito moyenera, samapangitsa kuti pakhale zovuta, amalimbana bwino ndi ntchito yake yayikulu - kutsitsa shuga wamagazi, ndikuthandizira kutaya zochuluka zonse poyamba. Ndimatenga tsiku lililonse mlingo wa 850 mg.

Ndili ndi matenda a shuga a 2 omwe amandidalira, ndimakhala ndikumamwa Glucophage chaka chachisanu ndi chinayi kale. Poyamba ndidatenga Glucofage 500, mapiritsiwo adathandiza kwambiri, tsopano ndimatenga 1000 m'mawa ndi 2000 usiku. Glucose m'magazi idakalipobe kwambiri, koma ndikufuna kudziwa kuti kumwa insulin popanda mapiritsi sikutulutsa kanthu kofanana ndi Glucofage. Ndikuganiza kuti amandithandiza kwambiri. Koma kuchepa thupi kwa zaka zisanu ndi zinayi sikunawonedwe konse. Amapereka mankhwala ena kwaulere, koma ndimapiritsi a Glucofage omwe ndimamvanso bwino. Ndikudziwa kuti anthu ambiri amamwa mapiritsi awa, koma sagwira ntchito kwa ine, ndipo panalibe chowongolera. Zotsatira zoyipa sizinawonedwe. Wolekeredwa bwino.

Ndinayamba kumwa mankhwalawa mosamala, pa 250 mg. Pambuyo mwezi woyamba wa makonzedwe, shuga anali atayandikira pafupifupi (7-8 mayunitsi), ndipo kulemera kwake sikuima. Iyenso adadabwa ataona mamilimita atatu osapindulitsa pamiyezo ndipo ili ndi mwezi wokha.

Glucophage adandiuza ine endocrinologist wa kuwonda. Mlingo 850 mg, kawiri tsiku lililonse, piritsi limodzi. Amandidwalitsa. Ndinkadwalitsa chizungulire, ndinali ndimatumbo otayirira, ndipo nthawi zambiri ndimathamangira kuchimbudzi. Chifukwa chake, ndinayenera kusiya kumwa mapilitsiwa, patatha miyezi isanu ndi umodzi ndinasankha kuyesanso kumwa, koma tsoka, zotsatirazi ndizofanana, nseru kwambiri.

Adatenga "Glucophage 1000". Mimba yanga idayamba kupweteka kwambiri, ndipo sizinapite milungu iwiri. Adotolo adatanthauzira Glucophage Long - zonse zili m'dongosolo. Zowona, sindikutsimikiza kuti ndimafunikira mankhwalawa, ndilibe matenda ashuga, koma ndidapereka mankhwala a endocrinologist, ndiye ndimamwa. Kuthetsa matenda a insulin.

Type 2 shuga. Ndikuvomereza Glucophage Long. Imalekeredwa bwino. Ndimakonda kuti mungatenge kamodzi kokha patsiku.

Ndimamwa glucophage kwa zaka zitatu, 500 mg 2 kawiri pa tsiku. Kulemera kumachuluka tsiku lililonse. Musakonde mankhwalawo.

Mayi anga ali ndi matenda osokoneza bongo a digiri yachiwiri. Adalemba metformin, inde, amapatsa maulere zamagetsi, zotsika mtengo, zopanda ntchito. Koma tidaganiza kuti timugulira glucophage. Glucophage ndi mankhwala oyamba, makamaka France. Mtundu wabwino kwambiri komanso mtengo wokwanira. Adayesa mankhwala ena - otsika mtengo komanso okwera mtengo, koma amakhazikika pamenepo.

Pa mlingo wapamwamba 500, mutu wanga unayamba chizungulire. Ndinayeneranso kutsanso mlingo. Ngakhale kulolerana kuli bwino kuposa siofora.

Ndili ndi matenda ashuga 2: Ndili pachakudya, ndimachita masewera, ndikudzigaya ndekha ndi madzi ozizira. Glucose sapitirira 7, ndikulakalaka aliyense akhale ndi mwayi wokhala opanda mapiritsi.

Apongozi anga ali ndi matenda a shuga, amatenga Glucofage. Kalanga ine! M'mafakitala ambiri, ma dummies amagwiritsidwa ntchito m'malo mwa mankhwala. Mnzake wochokera ku Germany adabwera kwa apongozi anga (nawonso amatenga mankhwalawa), adagula mu mankhwala athu ndipo patsiku lachiwiri shuga wake udayambanso. Ndinatenga mapiritsi otsalawo kunyumba nane, ndinawupima kuti aunike, voila - mavitamini. Chifukwa chake, ndibwino kuti mugule mumasitolo odalirika kapena m'malo osungiramo katundu. Pali makampani ambiri ogulitsa ndi fake.

Pambuyo pobadwa kwa mwana, adanenepa kwambiri. Zomwe sindinayese - zakudya zosiyanasiyana, tiyi ndi glucophage kuphatikiza. Malinga ndi zomwe ndapeza, ndimachepetsa thupi, koma osati zambiri. Thirani makilogalamu 7 m'miyezi iwiri. Zowona, khungu pamimba yanga yolimba ndikuwongola matumbo lidapita. Lamulo lofunika kwambiri ndikuwonetsetsa kuti muzidya zakudya zoyenera ndi zakudya. Kutsekemera ndi mafuta kunatheratu. Zakudya zake zinali zomanga thupi. Amayi anali atachita masewera olimbitsa thupi kunyumba, adathamanga m'mawa, mwamuna wake adayamba kudandaula kuti akudzuka, koma ine kulibe. Ndiye, mwachidziwikire, ndidakondwera kwambiri ndi zotsatira kuposa ine. Glucophage inandithandiza kuchepa thupi, chamoyo chilichonse chimakhala payekha ndipo zochita zake zimakhala zosiyanasiyana. Onetsetsani kuti mwayang'ana dokotala musanagwiritse ntchito, monga momwe ndidachitira.

Mayi anga akhala ndi matenda a shuga kwa zaka zambiri. Anayamba kugwiritsa ntchito insulin zaka zisanu zapitazo. Ndipo chaka chatha, adokotala adamuwuza Glucophage. Chifukwa chake ndi cholesterol yowonjezera komanso zovuta zama metabolic. Amayi anali bwino ndipo anali ndi vuto loti anali kupuma - sanadzuke mpaka pachipansi chachiwiri. Pambuyo pa miyezi isanu ndi umodzi ya kumwa glucophage, kuyesedwa kwa cholesterol, khungu la chidendene linasiya kuphulika ndipo mkhalidwe wamba unasintha. Amayi akupitilizabe kumwa mankhwalawa, koma amawunikira zakudya - izi ndizofunikira kuti ayike glucophage.

Kufotokozera kwapfupi

Masiku ano, ma endocrinologists ali ndi mitundu yambiri ya mankhwala omwe amachepetsa shuga omwe ali ndi umboni wokwanira wotetezeka komanso kuchita bwino kwawo. Ndizodziwika kale kuti mchaka choyamba chogwiritsira ntchito mankhwalawa pochiza matenda a shuga, kugwiritsa ntchito bwino kwamagulu osiyanasiyana a othandizira a hypoglycemic (biguanides, sulfonylamides), ngati akusiyana, sikofunika. Pankhani imeneyi, popanga mankhwala, munthu akuyenera kuwongoleredwa ndi zina zomwe zimagwiritsidwa ntchito ndi mankhwalawa, monga: momwe mtima ndi mitsempha yamagazi imalumikizana ndi kudya kwawo kwa zovuta zazikulu zam'magazi, chiopsezo cha kuyambuka ndi kuchuluka kwa atherogenic pathologies. Inde, ndi “nthomba” yoyambira yokha imeneyi yomwe imafunsa mwachangu funso loti "kodi pali moyo pambuyo pa matenda ashuga?" Kuyang'anira kwa nthawi yayitali kuchuluka kwa shuga m'magazi kumakhala kovuta kwambiri chifukwa cha kuwonongeka kwamphamvu kwa ntchito ya β-cell. Pachifukwa ichi, kufunikira kwa mankhwala oteteza maselo, mphamvu zawo ndi ntchito zake zikukula. Mwa mulu wazidziwitso zamayendedwe azachipatala ndi miyezo yothandizira matenda ashuga omwe adatengedwa m'maiko osiyanasiyana, mzere wofiira ndi dzina lomwelo: glucophage (INN - metformin). Chithandizo cha hypoglycemic ichi chakhala chikugwiritsidwa ntchito polimbana ndi matenda a shuga 2 kwazaka zoposa makumi anayi. Glucophage, ndiye, mankhwala okhawo odana ndi shuga omwe amathandizira kuchepetsa zovuta za matenda ashuga. Izi zidawonetsedwa bwino mu kafukufuku wamkulu yemwe adachitika ku Canada, pomwe odwala omwe amatenga glucophage anali ndi ziwengo zonse za 40% zamitima yakufa poyerekeza ndi omwe amamwa sulfonylureas.

Mosiyana ndi glibenclamide, glucophage simalimbikitsa kupanga kwa insulin komanso sikuti imapangitsa kuti zochita za hypoglycemic zisinthe. Makina akulu a zochita zake amakhala ndi cholinga chowonjezera mphamvu ya zotumphukira minofu yolandirira (makamaka minofu ndi chiwindi) ku insulin. Poyerekeza zakumbuyo ya insulin, glucophage imakulanso kugwiritsidwa ntchito kwa glucose pogwiritsa ntchito minofu ndi matumbo. Mankhwala amapititsa patsogolo kukhathamiritsa kwa glucose popanda mpweya ndipo amathandizira kupanga glycogen mu minofu. Kugwiritsa ntchito glucophage kwanthawi yayitali kumakhudzanso kagayidwe ka mafuta, komwe kumayambitsa kuchepa kwa kuchuluka kwa cholesterol (LDL) yathunthu m'magazi.

Glucophage imapezeka m'mapiritsi. Nthawi zambiri, kudya kumayamba ndi kumwa kwa 500 kapena 850 mg katatu patsiku pakudya kapena mutatha kudya. Nthawi yomweyo kuyang'anitsitsa shuga m'magazi kumachitika, malinga ndi zotsatira za kuchuluka kwakukulu kwa mlingo mpaka 3000 mg patsiku ndikotheka. Mukamamwa glucophage, odwala omwe amakhala ndi "zakudya" zawo zam'magazi amayenera kugawa chakudya chilichonse chomwe chimaperekedwa patsiku. Ndi kunenepa kwambiri, zakudya zama hypocaloric zimasonyezedwa. Glucofage monotherapy, monga lamulo, sagwirizana ndi hypoglycemia, komabe, mukamamwa mankhwalawo ndi othandizira ena a antihyperglycemic kapena insulin, muyenera kukhala osamala ndikuwonetsetsa magawo anu a biochemical.

Pharmacology

Oral hypoglycemic mankhwala ochokera pagulu la Biguanide.

Glucophage ® imachepetsa hyperglycemia, popanda kutsogola kukula kwa hypoglycemia. Mosiyana ndi zotumphukira za sulfonylurea, sizimalimbikitsa kutulutsa insulin ndipo sizikhala ndi vuto loti munthu azikhala wathanzi.

Zimawonjezera chidwi cha zotumphukira zolandilira ku insulin ndikugwiritsa ntchito shuga ndi maselo. Imachepetsa kupanga shuga kwa chiwindi poletsa gluconeogeneis ndi glycogenolysis. Kuchepetsa mayamwidwe m'matumbo.

Metformin imalimbikitsa kapangidwe ka glycogen pochita glycogen synthetase. Kuchulukitsa kuchuluka kwa mayendedwe amtundu uliwonse wa ma membrane glucose.

Kuphatikiza apo, ili ndi phindu pa metabolidi ya lipid: imatsitsa cholesterol yathunthu, LDL ndi TG.

Ngakhale mutamwa metformin, thupi la wodwalayo limakhalabe lolimba kapena limatsika pang'ono.

Pharmacokinetics

Mutatha kumwa mankhwalawo mkati, metformin imatenga gawo lonse la chakudya. Ndi kuyamwa kwa munthawi yomweyo, kuyamwa kwa metformin kumachepetsedwa ndikuchedwa. Mtheradi bioavailability ndi 50-60%. C_max mu plasma pafupifupi 2 μg / ml kapena 15 μmol ndipo zimatheka pambuyo maola 2,5.

Metformin imagawidwa mwachangu mu minofu ya thupi. Sizikugwirizana ndi mapuloteni a plasma.

Amachepetsa pang'ono ndi kupukusidwa ndi impso.

Kuvomerezeka kwa metformin mwa anthu athanzi ndi 400 ml / min (kanthawi kuposa KK), komwe kumawonetsa katulutsidwe ka tubular.

T_1/2 pafupifupi maola 6.5

Pharmacokinetics mu milandu yapadera yamankhwala

Odwala ndi aimpso kulephera T_1/2 ukuwonjezeka, pamakhala chiwopsezo cha kukopeka kwa metformin mthupi.

Kutulutsa Fomu

Mapiritsi, oyera-okutira oyera, ozungulira, biconvex, pamtanda - gulu loyera loyera.

Omwe amathandizira: povidone - 20 mg, magnesium stearate - 5.0 mg.

Zomwe zimapangidwa ndi nembanemba wa filimu: hypromellose - 4.0 mg.

Ma PC 10 - matuza (3) - mapaketi a makatoni.
Ma PC 10 - matuza (5) - mapaketi a makatoni.
15 ma PC. - matuza (2) - mapaketi a makatoni.
15 ma PC. - matuza (4) - mapaketi a makatoni.
20 ma PC. - matuza (3) - mapaketi a makatoni.
20 ma PC. - matuza (5) - mapaketi a makatoni.

Mankhwala amatengedwa pakamwa.

Monotherapy ndi kuphatikiza mankhwalawa ndi ena othandizira pakamwa

Mulingo woyambira woyamba ndi 500 mg kapena 850 mg 2-3 nthawi / tsiku mutadya kapena pakudya. Kuwonjezereka kwapang'onopang'ono kwa mlingo kumatha kutengera kuchuluka kwa shuga m'magazi.

Mankhwala okonza mankhwalawa nthawi zambiri amakhala 1500-2000 mg / tsiku. Kuti muchepetse mavuto kuchokera m'matumbo am'mimba, mlingo wa tsiku ndi tsiku uyenera kugawidwa mu Mlingo wa 2-3. Mlingo wapamwamba kwambiri ndi 3000 mg / tsiku, wogawidwa mu 3 waukulu.

Kuchepetsa pang'ono kwa mankhwalawa kungathandize kusintha kulolerana kwa m'mimba.

Odwala omwe amalandila metformin mu Mlingo wa 2000-3000 mg / tsiku amatha kusamutsidwa ku mankhwala Glucofage ® 1000 mg. Mlingo woyenera kwambiri ndi 3000 mg / tsiku, womwe umagawidwa pazigawo zitatu.

Ngati mukufuna kusintha kuti mumwe mankhwala ena a hypoglycemic, muyenera kusiya kumwa mankhwalawa ndikuyamba kumwa Glucofage ® mu mlingo womwe tafotokozawu.

Kuphatikiza kwa insulin

Kukwaniritsa bwino shuga wamagazi, metformin ndi insulin zitha kugwiritsidwa ntchito ngati mankhwala ophatikiza. Mlingo woyamba wa Glucofage ® ndi 500 mg kapena 850 mg kawiri / tsiku, pomwe mlingo wa insulin umasankhidwa potengera kuchuluka kwa shuga m'magazi.

Ana ndi achinyamata

Mwa ana azaka zapakati pa 10 ndi kupitirira, Glucofage ® ikhoza kugwiritsidwa ntchito ngati monotherapy komanso kuphatikiza insulin. Mulingo woyambira woyamba ndi 500 mg kapena 850 mg 1 nthawi / tsiku mukatha kudya kapena pakudya. Pambuyo masiku 10-15, mlingo uyenera kusinthidwa potengera kuchuluka kwa magazi. Mulingo wambiri watsiku ndi tsiku ndi 2000 mg, wogawidwa pamitundu iwiri.

Odwala okalamba

Chifukwa cha kuchepa kwa ntchito yaimpso, mlingo wa metformin uyenera kusankhidwa poyang'aniridwa kawirikawiri a impso function (kudziwa zomwe zili serum creatinine osachepera 2-4 pachaka).

Glucofage ® iyenera kumwedwa tsiku lililonse, osasokoneza. Ngati chithandizo chalekeka, wodwalayo ayenera kudziwitsa dokotala.

Bongo

Zizindikiro: mukamagwiritsa ntchito metformin pa mlingo wa 85 g (pafupipafupi 42,5 mlingo waukulu wa tsiku ndi tsiku), hypoglycemia siinawoneke, komabe, kukula kwa lactic acidosis kunadziwika.

Zofunikira kwambiri za bongo kapena zovuta zomwe zingagwirizane nazo zimatha kuyambitsa lactic acidosis.

Chithandizo: kuchoka kwa mankhwala Glucofage ®, kuchipatala mwachangu, kutsimikiza mtima kwa lactate m'magazi, ngati kuli koyenera, kuchitira mankhwala. Kuchotsa lactate ndi metformin m'thupi, hemodialysis imakhala yothandiza kwambiri.

Kuchita

Iodine-yokhala ndi radiopaque othandizira: motsutsana ndi kagwiritsidwe ntchito ka mphamvu yaimpso kwa odwala omwe ali ndi matenda osokoneza bongo, kafukufuku wama radiology ogwiritsa ntchito ayodini wokhala ndi radiopaque othandizira angayambitse kukula kwa lactic acidosis. Kuchiza ndi Glucofage ® kuyenera kuthetsedwa malinga ndi ntchito ya impso maola 48 asanafike kapena panthawi yomwe mayeso a X-ray amagwiritsa ntchito ayodini wokhala ndi ma radiopaque othandizira ndipo osayambiranso kale kuposa maola 48 atatha, pokhapokha ngati pakuwunika ntchito ya impso idadziwika kuti ndi yachilendo.

Ethanol - kuledzera kwadzaoneni, chiopsezo chokhala ndi lactic acidosis imachuluka, makamaka pankhani ya:

- kuperewera kwa zakudya m'thupi, zakudya zopatsa mphamvu zochepa,

Pogwiritsa ntchito mankhwalawa, mowa ndi mankhwala okhala ndi ethanol ayenera kupewedwa.

Kuphatikiza komwe kumafunikira kusamala

Kugwiritsa ntchito nthawi yomweyo danazol osavomerezeka kuti apewe hyperglycemic zotsatira za chomaliza. Ngati mankhwala a danazol akufunika ndipo atayimitsa koyamba, kusintha kwa mankhwala Glucofage ® kumafunikira motsogozedwa ndi kuchuluka kwa shuga m'magazi.

Chlorpromazine akamagwiritsa ntchito muyezo waukulu (100 mg / tsiku) amawonjezera kuchuluka kwa shuga m'magazi, kuchepetsa kutulutsa kwa insulin. Mankhwalawa antipsychotic ndipo atayimitsa chomaliza, kusintha kwa mankhwalawa kumafunikira motsogozedwa ndimagazi a shuga.

GCS yogwiritsira ntchito mwadongosolo komanso yakomweko kumachepetsa kulolera kwa glucose, kuonjezera kuchuluka kwa shuga m'magazi, nthawi zina kumapangitsa ketosis. Mankhwalawa corticosteroids ndipo atayimitsa kudya kwa chakumapeto, kusintha kwa mankhwala Glucofage ® kumafunika motsogozedwa ndi kuchuluka kwa shuga m'magazi.

Kugwiritsa ntchito munthawi yomweyo mankhwala a "loop" okodzetsa kungayambitse kukula kwa lactic acidosis chifukwa chakulephera kugwira ntchito kwaimpso. Glucofage ® sayenera kukhazikitsidwa ngati CC ili yochepera 60 ml / min.

Beta₂-adrenomimetics mu mawonekedwe a jakisoni amawonjezera kuchuluka kwa shuga m'magazi chifukwa chokondoweza kwa β₂-makampani. Poterepa, ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi. Ngati ndi kotheka, tikulimbikitsidwa kupereka insulin.

Pogwiritsa ntchito nthawi yomweyo mankhwala omwe ali pamwambawa, kuwunika pafupipafupi magazi a shuga kungafunike, makamaka kumayambiriro kwa chithandizo.Ngati ndi kotheka, mlingo wa metformin ungasinthidwe munthawi yamankhwala ndikatha.

Ma A inhibitors komanso mankhwala ena a antihypertensive amatha kuchepetsa magazi. Ngati ndi kotheka, mlingo wa metformin uyenera kusinthidwa.

Ndi munthawi yomweyo kugwiritsa ntchito mankhwala Glucofage ® ndi sulfonylurea zotumphukira, insulin, acarbose, salicylates, kukula kwa hypoglycemia ndikotheka.

Nifedipine imachulukitsa mayamwidwe ndi C_max metformin.

Mankhwala a Cationic (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren, trimethoprim ndi vancomycin) omwe amatulutsidwa mu renal tubules kupikisana ndi metformin kwa machitidwe oyendetsa ma tubular ndipo angayambitse kuchuluka kwa C_max.

Zotsatira zoyipa

Kutsimikiza kwamafupipafupi a mavuto: pafupipafupi (≥1 / 10), nthawi zambiri (1001/100, ® angagwiritsidwe ntchito ngati monotherapy komanso kuphatikiza ndi insulin. Nthawi zonse mlingo wa 500 mg kapena 850 mg 1 nthawi / tsiku pambuyo Pakadutsa masiku 10-15, mlingo uyenera kusinthidwa molingana ndi kuchuluka kwa shuga m'magazi. Mlingo wambiri watsiku ndi tsiku ndi 2000 mg, wogawidwa mu Mlingo wa 2-3.

Malangizo apadera

Lactic acidosis ndizosowa koma zowopsa (kuchuluka kwaimfa pakalibe chithandizo chamankhwala mwadzidzidzi) zomwe zingachitike chifukwa cha kuphatikizika kwa metformin. Milandu ya lactic acidosis mutatenga metformin imapezeka makamaka mwa odwala omwe ali ndi matenda osokoneza bongo omwe amalephera kwambiri aimpso.

Zina zokhudzana ndi chiopsezo ziyenera kuganiziridwanso, monga matenda a shuga oopsa, ketosis, kusala kudya kwa nthawi yayitali, uchidakwa, kulephera kwa chiwindi, komanso vuto lililonse lomwe lingakhale ndi hypoxia. Izi zitha kuthandiza kuchepetsa zochitika za lactic acidosis.

Kuopsa kwa lactic acidosis kuyenera kuganiziridwanso ngati zizindikiro zosadziwika, monga kupsinjika kwa minofu, limodzi ndi zizindikiro za dyspeptic, kupweteka kwam'mimba komanso asthenia yayikulu. Lactic acidosis imadziwika ndi kufupika kwa acidotic, kupweteka kwam'mimba komanso hypothermia, kenako kutsekeka.

Diagnostic labotale magawo ndi kuchepa kwa magazi pH (® sikuyambitsa hypoglycemia, chifukwa chake, sizikhudza kuthekera kuyendetsa magalimoto ndi machitidwe. Komabe, odwala ayenera kuchenjezedwa za kuopsa kwa hypoglycemia mukamagwiritsa metformin kuphatikiza mankhwala ena a hypoglycemic (kuphatikiza mankhwala ena a hypoglycemic) zotumphukira sulfonylurea, insulin, repaglinide).

Kufotokozera kwathunthu kwa mankhwalawa, mawonekedwe ake ndi mawonekedwe ake omasulidwa

Mu mapiritsi Glucofage, mankhwala othandizira omwe amapanga kwambiri ndi metformin, yomwe imakonzekera mawonekedwe a hydrochloride.

Mankhwalawa amapangidwa ngati mapiritsi, omwe amaphatikizidwa ndi zokutira filimu.

Kuphatikiza pazomwe zimagwiritsidwa ntchito popanga mankhwala, kapangidwe kazinthu kameneka kamagwiritsanso ntchito zinthu zina zomwe zimapatsidwa ntchito zothandizira.

Izi zothandiza zomwe zimapanga glucophage ndi:

Utoto wamafilimu wa mankhwalawo umaphatikizanso mu mawonekedwe ake monga hypromellase.

Mapiritsiwo amakhala ndi mawonekedwe a biconvex. Mukuwoneka, gawo lamtanda la phale ndi unyinji wowoneka bwino wokhala ndi khungu loyera.

Mankhwalawa amadzaza m'matumba a 20 mapiritsi. Mapaketi atatu amtunduwu amaikidwa m'matumba, omwe amakhalanso ndi malangizo ogwiritsira ntchito mankhwalawa.

Mankhwalawa amagwiritsidwa ntchito pochiza matenda amishuga amitundu iwiri, monga monotherapy komanso pochita zovuta za mtundu wa matenda a shuga 2.

Kugwiritsa ntchito glucophage pamaso pa matenda a shuga m'magonedwe kumatha kuchepetsa matendawa. Kugwiritsa ntchito mankhwalawa popewa matenda ashuga kupezeka kwa matenda a prediabetes m'thupi kungathandize kuchepetsa mwayi wokhala ndi matenda ashuga.

Kugwiritsa ntchito mankhwalawa kumakuthandizani kuti muzitha kuyendetsa bwino.

Zizindikiro ndi contraindication ntchito mankhwala

Glucophage amalimbikitsidwa kwa odwala omwe ali ndi mtundu wa shuga wachiwiri, makamaka odwala omwe ali onenepa kwambiri.

Kugwiritsa ntchito mankhwalawa kumalimbikitsidwa pokhapokha pakutha kwa zakudya zopatsa thanzi komanso zolimbitsa thupi.

Mankhwalawa amaloledwa kugwiritsidwa ntchito ndi onse akulu ndi ana omwe ali ndi zaka 10.

Malangizo ogwiritsira ntchito Glucofage amalimbikitsa kumwa mankhwalawa ngati prophylactic wothandizidwa ndi wodwala yemwe wapeza matenda a prediabetes omwe ali ndi chiopsezo chowonjezereka pakukula kwa matenda a shuga a mtundu II.

Monga chida chothandizira kupewa, mankhwalawa amayenera kugwiritsidwa ntchito ngati kusintha kwa moyo ndi zakudya sizikulola kukwaniritsa kukonza shuga mu madzi a m'magazi.

Monga mankhwala aliwonse, Glucophage imakhala ndi zotsutsana zingapo kuti zigwiritsidwe.

Milandu ikuluikulu pakugwiritsa ntchito mankhwalawa ndi iyi:

1. kukhalapo kwa hypersensitivity pazinthu zazikulu kapena zowonjezera zomwe zimapanga mankhwala.
2. Kukhalapo kwa thupi la wodwala wodwala matenda ashuga, matenda ashuga ketoacidosis, diabetes kapena matenda atangoyamba kumene.
3. Kukhalapo kwa wodwala ndi kulephera kwa impso kapena kugwira bwino ntchito kwa impso.
4. The zimachitika pachimake zinthu zomwe zimachitika mthupi ndi kuoneka ngati chiwopsezo cha kusokonezeka kwa impso. Zinthu ngati izi zimaphatikizapo kusowa kwamadzi, kutsegula m'mimba, kapena kusanza.
5. Kukula kwa matenda opatsirana owopsa komanso opatsirana m'thupi komwe kumakhudza kugwira ntchito kwa impso.
6. Kukhalapo kwa wodwala kwamawonekedwe owopsa kapena matenda opweteka kwambiri omwe angayambitse matenda a minofu hypoxia, mwachitsanzo, kulephera kwa mtima, kulephera kwa mtima komwe kumachitika chifukwa cha kusakhazikika kwa magawo a hemodynamic, kupuma, kugunda kwa mtima.
7. Kuchita zodzionetsera zambiri pakagwiritsidwe ntchito ka mankhwala a insulin.
8. Kukhalapo kwa chiwindi kulephera ndi chiwindi cell ntchito.
9. Kukhalapo kwa uchidakwa woperewera kwa wodwala, poyizoni wazakumwa ndi zakumwa zoledzeretsa.
10. Nthawi ya bere ndi kuyamwitsa.
11. Kafukufuku wokhudzana ndi kugwiritsa ntchito mankhwala okhala ndi ayodini monga gulu lina.
12. Kugwiritsa ntchito zakudya zamafuta ochepa.

Musanagwiritse ntchito mankhwalawa, ndikofunikira kuti mufunsane ndi dokotala.

Malangizo ogwiritsira ntchito mankhwalawa

Mankhwalawa adapangira pakamwa.

Amagwiritsidwa ntchito pa monotherapy kapena ngati gawo limodzi la zovuta pakulipira matenda a shuga.

Mukasinthira kugwiritsa ntchito Glucophage ngati mankhwala okhawo a hypoglycemic, muyenera kusiya kugwiritsa ntchito mankhwala ena omwe ali ndi vuto lofanana ndi la wodwalayo la 2 shuga.

Mukamapangira monotherapy ndi glucophage, mankhwalawa amathandizidwa kugwiritsidwa ntchito pazotsatira komanso kukhazikitsa malamulo ena:

• Mulingo woyenera wa mankhwalawa ndi 500 mg 2-3 Mlingo patsiku, mankhwala ayenera kumwedwa mutatha kudya kapena nthawi yomweyo,
• pa monotherapy tikulimbikitsidwa kuti muyezo wa glycemia masiku onse 10 ndikusintha Mlingo wa mankhwalawa malinga ndi zotsatira zake,
• Mukamamwa mankhwalawa, muyezo muzipita pang'onopang'ono, njira yothandizira mankhwalawa imathandiza kupewa kuwoneka ngati zoyipa m'magazi,
• Ngati mulingo wokonza, muyezo wa mankhwala wofanana ndi 1500-2000 mg patsiku uzigwiritsidwa ntchito,
• Kuti muchepetse mavuto
• mulingo woyenera tsiku lililonse sayenera kupitirira 3000 mg patsiku.

Kuti mukwaniritse bwino kwambiri kuchokera pa kugwiritsa ntchito mankhwalawa, mutha kugwiritsidwa ntchito ngati imodzi mwazinthu zovuta kuzitsatira.

Nthawi zambiri, mankhwalawa amagwiritsidwa ntchito limodzi ndi insulin.

Mukamachita chithandizo chotere, mlingo wa Glucophage wotengedwa uyenera kukhala 500 mg katatu patsiku. Ndipo Mlingo wa mankhwala okhala ndi insulin ya mahomoni amasankhidwa molingana ndi kuchuluka kwa kuchuluka kwa shuga m'magazi a wodwala.

Pochita monotherapy ndi prediabetes, kumwa mankhwalawa akulimbikitsidwa pa mlingo wa 1000-1700 mg patsiku. Mlingo wa tsiku ndi tsiku wa mankhwalawa umayenera kugawidwa mu 2 Mlingo.

Kuchita monotherapy ndi prediabetes kumafuna kuwunika pafupipafupi kwa plasma glycemia.

Kutalika kwa glucophage makonzedwe ndi dokotala. Imwani mankhwalawa osasokoneza.

Zotsatira zoyipa mukamamwa mankhwalawa

Zotsatira zoyipa zomwe zimachitika pakumwa mankhwalawa zimatha kugawidwa m'magulu angapo kutengera kupezeka kwawo.

Nthawi zambiri, mthupi la wodwala mukamagwiritsa ntchito mankhwala Glucofage, zosokoneza zimatulukira mu kagayidwe kachakudya ka kagayidwe kake ndi kagwiritsidwe ntchito ka chakudya m'mimba. Mwina kukula kwa lactic acidosis.

Kugwiritsa ntchito mankhwalawa kwakanthawi kumabweretsa kuchepa kwa mayamwidwe a vitamini B12 wodwala.

Wodwala akaulula zizindikiro za kuchepa kwa magazi m'thupi la megaloblastic, njira zonse zofunika ziyenera kutengedwa nthawi yomweyo kuti muchepetse vuto.

Nthawi zambiri, odwala omwe amagwiritsidwa ntchito ngati mankhwala ochiritsira amakhala akusokoneza malingaliro awo.

Kuchokera m'mimba, mawonekedwe a zoyipa monga:

1. Matenda a shuga
2. Kumva kupusa.
3. Kubweza.
4. Ululu m'mimba.
5. Anachepetsa chilako.

Nthawi zambiri, zotsatira zoyipazi zimachitika poyambira kumwa mankhwalawo ndipo nthawi zambiri, zotsatira zake zimatha pang'onopang'ono ndikugwiritsanso ntchito mankhwalawa.

Nthawi zina, mukamamwa mankhwalawa, khungu limakhudzika m'njira zosiyanasiyana zotupa ndi kuyabwa.

Mndandanda wa mankhwalawa, umawunikira za mtengo wake

Kugulitsidwa kwa Glucophage kuchokera ku matenda a shuga kungapangike ku malo aliwonse opanga mankhwala, malinga ngati wodwalayo ali ndi mankhwala omwe adalembedwa ndi adokotala. Mtengo wa mankhwalawa ku Russia umachokera pa 124 mpaka 340 rubles pa phukusi, kutengera dera lomwe lili mdzikolo.

Ndemanga za mankhwalawa zimawonetsa kuti ndiwothandiza pa matenda a hypoglycemic, omwe, kuphatikiza pa kuwongolera kuchuluka kwa shuga m'magazi amwazi, angakhudze mayeso amthupi la wodwala ndipo, ngati kunenepa kwambiri, kumachepetsa.

Ndemanga zoyipa za mankhwalawa ndizosowa kwambiri ndipo nthawi zambiri mawonekedwe awo amakhudzana ndi kuphwanya kwamalangizo ogwiritsira ntchito mankhwalawa.

Ma fanizo odziwika bwino a mankhwala ndi awa:

Nthawi zambiri, Glucophage Long imagwiritsidwa ntchito ngati analog. Mankhwala ali ndi nthawi yayitali yogwira ntchito. Mutha kugula Glucophage Long, ngati analogue ina iliyonse, ku bungwe lililonse lazamankhwala. Kuti mupeze mankhwala amtunduwu, mankhwala a dokotala amafunikiranso. Mtengo wa analogues wa mankhwalawa uli pafupi ndi mtengo wa Glucofage. Kanemayo munkhaniyi afotokoza zamankhwala pambuyo pake.