Glycated hemoglobin - ndi chiyani

Kwa nthawi yayitali, matenda a shuga amatha kuoneka ngati amisala, kapena wodwala sangazindikire zowopsa.

Izi zimabweretsa zotsatira zosasinthika.

Kusanthula kwa glycosylated hemoglobin ndiko kuphunzira kopindulitsa kwambiri pakupezeka kwa matenda ashuga, kuphatikiza koyambirira kwake. Ganizirani momwe mungaperekere magazi, ndi zomwe zotsatira zake zingakambirane.

Ubongo wamwazi pa HbA1C: ndi chiyani?

Mlingo wa hemoglobin wa glycated umakulolani kuti mupeze gawo liti la hemoglobin lomwe limalumikizana ndi glucose pazomwe zimachitika, zomwe shuga ndi amino acid amalowa polowa kwa glucose kudzera mu membala wa erythrocyte.

Izi zimachitika mosalekeza mthupi, koma ngati shuga “amalumphira” m'magazi, ndiye kuti kuchuluka kwa glucose m'maselo ofiira kumakhala kosakhazikika (kumakhalabe mpaka miyezi inayi).

Nthawi zambiri, kuwunika kumayendetsedwa ngati anthu oganiza kuti ali ndi matenda a shuga, komanso kuwunika momwe matenda omwe akupezekera kale a endocrine.

Poyerekeza ndi kusanthula kwakanthawi kofulumira kudziwa kuchuluka kwa shuga m'magazi, chizindikiro chotere cha glycosylated hemoglobin chimakhala chothandiza kwambiri.

Nayi kusiyana kofunikira:

• zikuwonetsa kuchuluka kwapakati pamiyezi itatu yapitayo, zomwe zikutanthauza kuti kupusitsa dokotala pakungokhala pakudya kwa masiku angapo musanayambe kuwunikira kumalephera,
• hemoglobin ya glycated mwina sizitengera mphamvu ya zinthu zakunja, chifukwa imawonetsa mtengo wapakati (kuyesedwa kwapafupipafupi "kumatha kubera" chifukwa cha matenda akale, kupsinjika, zolimbitsa thupi kapena zinthu zina,.
• glycosylated hemoglobin imalola kuti adokotala awone bwino momwe zimasokoneza kagayidwe kazakudya m'thupi.

Kuti adziwe chithunzithunzi, madokotala amazindikira hemoglobin woikidwa ndi HbA1C. Kuyesedwa koteroko ndikokwera mtengo kwambiri (mtengo wokwera ndiye njira yokhayo yomwe ungagwiritse ntchito) pongowunika mwachangu, koma ziyenera kuchitika ngati adokotala akuumirira.

Anthu odwala matenda ashuga ayenera kuyesedwa miyezi itatu iliyonse, anthu athanzi zaka zitatu zilizonse.

Njira yotsimikiza ya glycosylated hemoglobin m'magazi

Zaka makumi atatu zapitazo, njira yophunzitsira iyi idapangidwa.

Tilembani njira zomwe zigwiritsidwe ntchito pano:

1. ntchito yayikulu yamadzimadzi. Ubwino: Zotsatira zolondola zokhazikitsidwa ndi chosinkhira mumawotomala. Njirayi ndiokwera mtengo kwambiri,
2. ion kusinthana chromatography. Kafukufukuyu ndiwovuta kwambiri, ndi ma labotor ochepa okha omwe ali ndi zida zofunika,
3. otsika mavuto ion kusinthana chromatography. Kusanthula kwakonzedwa mumphindi zisanu zokha, kukhazikitsa palokha ndikosavuta. Imodzi mwanjira zachangu kwambiri komanso zamakono,
4. immunoturbidimetry - Njira ina yolondola kwambiri (mtengo wake ndi wotsika pang'ono poyerekeza ndi chromatography),
5. zida zonyamula. Ku Russia, sanalandirebe zofalitsa zambiri, komabe, ambiri ochokera kumayiko ena amakhala ndi owunikira mafoni kunyumba.

Monga lamulo, cholakwika pakuwonetsa kuchuluka kwa glycogemoglobin ndi chochepa kwambiri ndipo sikudalira kwambiri njira zosankhazi zosankhidwa.

Zizindikiro zakusanthula

Ngati ndi kotheka, muyezo wa hemoglobin wa glycosylated umatsimikizika mwa ana, achinyamata, komanso achikulire, kuphatikizapo amayi apakati.

• matenda okayikira kapena zovuta zina za carbohydrate metabolism,
• pakati mwa azimayi omwe ali pachiwopsezo (monga lamulo, kuwunikiratu kumakonzekera masabata 10),
• mtundu 1 komanso matenda ashuga 2,
• Nthawi zina msambo wa hemoglobin wa glycated umatsimikiziridwa ndi matenda oopsa.

Chimodzi mwazinthu zabwino za njirazi ndikuti zimakupatsani mwayi wodziwa zovuta za endocrine kumayambiriro awo.

Glycosylated hemoglobin ndi chiyani?

M'magazi a munthu aliyense mumakhala mapuloteni - glycated hemoglobin (glycated hemoglobin). Imapezeka m'maselo a maselo ofiira am'magazi, omwe hemoglobin imagwira ntchito kwanthawi yayitali.

Mlingo wa hemoglobin womwe umayesedwa umatha kudziwa kuchuluka kwa hemoglobin m'magazi wolumikizidwa ndi glucose, ndipo zonsezi zimafotokozedwa ngati peresenti. Hemoglobin m'zinthu zathu imagwira ntchito yofunika, imakwaniritsa maselo onse ndi ziwalo zonse ndi mpweya.

Kuphatikiza apo, hemoglobin ili ndi gawo limodzi, imaphatikizana ndi shuga, komanso, njirayi singasinthe. Pambuyo pa kukomoka kotero, hemoglobin ya glycosylated imawonekera.

Glycosylated hemoglobin ikadzuka, pamakhala mwayi wopanga matenda a shuga, omwe amakhala oopsa kale kwa anthu.

Matenda a shuga ndi matenda ovuta kwambiri komanso owopsa kwa anthu, ali ndi zotsatira zosasintha zomwe zitha kubweretsa imfa. Ngati shuga sayendetsedwa.

Zowoneka bwino pazowunikiratu ndizofanana, sizingatulutsidwe, chifukwa chilichonse chomwe chidadyedwa ndi munthu m'miyezi itatu chikuwonetsedwa pamayeso. Pa mafomu oyesera, mayesowa akuwonetsedwa motere - HbA1C.

Muzochita zamankhwala, pali matebulo apadera omwe amafananizira kuchuluka kwa Glycated Nemoglobin ndi glucose:

Chifukwa chake, ku funso la glycosylated hemoglobin kuti ndi chiyani, yankho lotsatirali lingaperekedwe - iyi ndi hemoglobin yama cell ofiira am'magazi, omwe amalumikizidwa ndi glucose chifukwa chosasintha. Zambiri pazomwe zimawunikira zimawonekera kwa miyezi itatu, zomwe zimakupatsani mwayi wolamulira shuga. Kusanthula kwa glycosylated hemoglobin ndikofunikira pofufuza matenda - matenda ashuga.

Kusanthula kwa glycosylated hemoglobin: Momwe mungatenge, zabwinobwino

Kuwunikira kwa HbA1C kumakupatsani mwayi kuti mupeze shuga yanu kwa miyezi itatu. Iyi ndi njira yodalirika yomwe sikutanthauza kukonzekera mwapadera kuchokera kwa wodwala. Magazi owopsa kapena magazi a chala amatengedwa kuti aunikenso kusanthula kwake, kutengera kusanthula.

Komanso, mpanda wake umachitika nthawi ina iliyonse masana, simuyenera kufa ndi njala, kupewa thupi ndi kupsinjika. Kuwunikaku sikuyankha kuzizira, njira zotupa, zomwe zimakupatsani mwayi wambiri kuti mugwiritse magazi osadikirira kuti wodwalayo achiritse.

Magazi amatengedwa pafupifupi mamililita 2,5 kapena 3, komanso osakanikirana ndi mankhwala (anticoagulant) omwe amalepheretsa magazi kuwundana. Kusanthula kumatumizidwa ndikuvomerezedwa mwachangu komanso mopweteka. Kuyeza kumeneku kumakupatsani mwayi kudziwa zakudya zomwe wodwalayo anali atakhalapo.

Momwe mungayesere magazi a glycosylated hemoglobin?

Matenda a shuga amawopa mankhwalawa, ngati moto!

Muyenera kungolemba ...

Munthu sayenera kuphunzira maphunziro apadera.

Sikoyenera kubwera ku labotale pamimba yopanda kanthu - mutha kudya kadzutsa musanatenge magazi.

Zochita zolimbitsa thupi, kupsinjika, matenda am'mbuyomu komanso zinthu zina sizimakhudzanso kwambiri gawo lazowunikira. Wodwala amafunikira chinthu chimodzi chokha: pitani ku labotale nthawi iliyonse yabwino.

Mpandawo umapangidwa kuchokera mu mtsempha kapena chala (zimatengera ndi momwe wophatikizira amaikiramo chipatala china). Kusanthula kumatenga masiku atatu kapena anayi.

Matenda a chithokomiro komanso kuchepa kwa magazi m'thupi zomwe zimapezeka mwa anthu zimatha kusintha zotsatira zoyesa.

Kufotokozera zotsatira za kafukufuku: zikhalidwe malinga ndi zaka

Dokotala akutsimikizira kusakhala kwathunthu kwawopseza matenda a shuga ngati chizindikiro sichidaposa 5,7%.

Chifukwa chake, izi ndi zomwe glycated hemoglobin iyenera kukhala:

Chifukwa chake, kwa achinyamata athanzi labwino, phindu la 6.5% limatengedwa ngati chizolowezi. Awa ndi malire. Ngati zidapitilira, kuwonetseratu koyambirira kumapangidwa: matenda ashuga.

Kuyandikira 6.5% ndi chizindikiro choopsa kale. Chifukwa chake:

• akukhulupirira kuti chiopsezo chokhala ndi matenda ashuga kulibe kwathunthu ndi hemoglobin wa glycated mpaka 5,7%,
• Nthawi kuchokera pa 5.7 mpaka 6% ikuonetsa kuti muyenera kutsatira kwambiri zakudya komanso moyo,
• pamlingo wa 6.1 ndi 6.4, chiopsezo cha matenda a shuga chikuwonjezeka kwambiri, ndibwino kukaonana ndi dokotala.

Ponena za kuchuluka kwa hemoglobin ya glycated mu ana, apa miyeso siyosiyana ndi akuluakulu - mwa ana athanzi lamatenda omwe sangakhale pachiwopsezo cha kupanga zovuta za metabolism ya carbohydrate, chisonyezo sichiyenera kupitirira 5.7%. Pazifukwa zakuthupi, mwa makanda m'miyezi yoyambirira ya moyo, mtengo wa 6.0% umatengedwa monga chizolowezi.

Ngati zizindikiro zikuwonjezeka, izi zikutanthauza chiyani?

Pankhaniyi, adotolo akuwunika kuti apange shuga. Komabe, kutali ndi kuchuluka konse kwa glycated hemoglobin kumawonetsa kuphwanya kwa kagayidwe kazachilengedwe.

Zifukwa zina zomwe zotsatira za mayeso a glycated hemoglobin zimakwezedwa:

• kusowa kwa ndulu,
• kutaya magazi kwambiri kumabwera kudzafufuza
• kuchepa kwazitsulo
• poyizoni wa mowa
• uremia (matenda a impso),
• kulephera kwa aimpso
• kuchuluka kwa hemoglobin ya fetal.

Glycohemoglobin imachulukanso ndi matenda amtundu 2 komanso matenda ashuga a 2. Poyamba, kuwonjezereka kwa chizindikirochi kumachitika chifukwa cha kutha kwachilendo pogawa chakudya (zomwe zimapangitsa kuchuluka kwa shuga), chachiwiri - chifukwa cholowetsedwa ndi insulin mthupi.

Kuwonjezeka kwa gawo la chidziwitso chowunikirachi ndi chizindikiro chowopsa chomwe chimafuna chithandizo chamankhwala ndi kuwongolera moyo.

Zifukwa zochepetsera chizindikiro pansipa

Ngati kuwunika kwachilengedwe kumawonetsa kuti glycogemoglobin "sinafike" pazomwe zimatanthawuza - zikutanthauza chiyani?

Tikulemba zifukwa zotheka kutsitsa chizindikiro pansipa

• achina,
• kutaya magazi kwaposachedwa
• kulakwitsa kwambiri kwa kapamba,
• chiwindi kapena matenda a impso,
• kuwonongeka msanga kwa maselo ofiira m'magazi.

Kutsika kwa hemoglobin wa glycated m'thupi kumakhala ndi chizindikiro chotchulidwa. Wodwala amakhala ndi vuto la kugona, kusawona bwino, kutopa kwambiri, kusakwiya komanso kukomoka.

Kusamalira mtengo

Mtengo wa kafukufuku wazomera zodalira mzindawu, njira yowerengera yomwe imagwiritsidwa ntchito, komanso labotale inayake.

Mtengo wotsika kwambiri wa ntchito m'magulu azachipatala a dziko lino ndi ma ruble 400, omwe ndi okwanira - pafupifupi ma ruble 1 chikwi.

Chifukwa cha kukwera mtengo, kutsimikiza kwa glycosylated hemoglobin amagwiritsidwa ntchito nthawi zambiri kuposa kuyesedwa kwa shuga kwa magazi. Komabe, ndikofunikira kumvetsetsa kuti njirayo siyofanana pankhani ya zidziwitso, komanso kuthekera "kuwonetsa" matenda ashuga m'mayambiriro oyambira.