Pancreatic lipase

LIPASE - (kuchokera ku Greek lipos ■ mafuta), pulotivomerezeka ya lipolytic ya gulu la esterase, i.e., ma enzyme omwe amawononga ma ester (esters) malinga ndi equation R.CO О R / + + H20 ^ RCOOH + R OH ku mowa ndi acid. Machitidwe a esterases amafikira ku ... Ensaikulopediya yayikulu ya zamankhwala

lipase - puloteni ya kalasi la hydrolase (EC 3.1.1.3), yomwe imathandizira kuwonongeka kwamphamvu kwa hydrolytic ya triglycerides mu glycerol ndi mafuta acids, imaperekedwa mwachitsanzo, pazinsinsi za kapamba ndi matumbo ... Mtanthauzira wamkulu wamankhwala

Pancreatic lipase - (pancreatic lipase, Eng. Pancreatic lipase)) (EC 3.1.1.3) puloteni yam'mimba ya gulu la lipases. Pochita lipids, pancreatic lipase imafanana ndi hepatic magazi lipase. Maphatikizidwe ndi gawo la pancreatic lipase ... ... Wikipedia

Pachimake kapamba - ICD 10 K85.85. ICD 9 577.0577.0 577.1577.1 ... Wikipedia

Kupukusa michere - Ma enzyme okugaya, michere yokugaya ndi michere yomwe imaphwanya zigawo zovuta za chakudya kukhala zinthu zosavuta zomwe zimalowetsedwa m'thupi. Mwanjira yayikulu, michere yamagayidwe amatchedwanso ma enzymes onse, ... ... Wikipedia

Ma enzyme opatsa mphamvu - Ma enzymes opangira chimbudzi amaphatikiza michere ya m'mimba yomwe imaphwanya zinthu zovuta kuzinthu zomwe zimapangidwa ndikulowa m'thupi. Malo ofunikira kwambiri a michere yam'mimba ndi gawo lamkamwa, ... ... Wikipedia

KUSINTHA - KUSINTHA. Pali mitundu iwiri ya P. intracellular ndi extracellular. Pa extracellular P., yofala pakati pazamoyo zapamwamba, njirayi imapitilira dongosolo lapadera la ziwalo zamatumbo a matumbo ake ndi zida zake zaminyewa. P. ndi chem. mwakuthupi ... Ensaikulopediya yayikulu ya zamankhwala

MTHANDA - MTHAZI, madzimadzi odzaza mitsempha, mitsempha ndi ma capillaries amthupi ndikupanga chikasu chowonekera. utoto wa plasma ndi zinthu zojambulidwa momwemo: maselo ofiira am'magazi, kapena maselo ofiira amwazi, oyera, kapena maselo oyera amitsempha yamagazi, ndi ...

Creon 10000 - Zosakaniza yogwira

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Kaphatikizidwe ndi udindo

Pancreatic lipase imapangidwa mu kapamba ndipo imasungika mu lumen ya duodenum ndikuyiyika m'matumbo ang'onoang'ono, pomwe imaphwanya mafuta azakudya - triglycerides - mu glycerol ndi mafuta apamwamba acids. Chifukwa chake, lipase iyi ndi puloteni yofunika pakukola mafuta. Pancreatic lipase hydrolyzes mamolekyulu amafuta omwe amachokera ku chakudya. M'matenda a kapamba, zochitika za lipase zimachuluka, ndipo lipase yambiri imayamba kutulutsidwa m'magazi. Kutsika kwa lipase kumatha kuchitika ndi khansa, kuphatikiza khansa ya kapamba, komanso kuperewera kwa chakudya m'thupi (priglycerides owonjezera chakudya).

Lipase: ndi chiyani

Zakudya zokhala ndi mapuloteni ovuta ndi mafuta sizingafanane ndi momwe zidalili. Atalowa m'matumbo, chakudya chomwe chimadyedwacho chimakhala ndi ma enzymes omwe amatha kuwononga zinthu zazing'onoting'ono. Zinthu ngati izi zimaphatikizapo amylase, proteinase ndi lipase. Thupi lomaliza limapangidwa ndi kapamba - tanthauzo la lipase iyi, yomwe imatchedwa pancreatic, imatha kuwoneka mu mzere umodzi wa kusanthula kwachembere.

Lipase ndi amodzi mwa michere yagaya yomwe imapangidwa ndi kapamba ndipo imagwira nawo ntchito pakukumba mafuta.

Komanso, lipase imapangidwa m'thupi ndi ziwalo zina:

• chiwindi - lipase yamtunduwu imakhala ndi lipids yachilendo ya plasma,
• kuwala
• matumbo
• m'mimba - lipase yamtunduwu imapezeka m'matumbo a m'mimba ndipo imathandizira hydrolysis yamafuta,
• milomo yamkamwa - enzyme imakhalapo mwa makanda okha, mtundu uwu wa lipase umalimbikitsa kuwonongeka kwa mkaka wa m'mawere.

Pancreatic lipase ili ndi chofunikira pakuwola kwamafuta omwe amachokera kunja ndi chakudya. Pakalibe enzyme iyi, mafuta omwe amalowa mthupi omwe amakhala ndi mphamvu yayikulu amatha kuchepetsedwa ndikukutuluka osasinthika. Kupezeka kwa lipase mulingo woyenera ndiye chinsinsi cha thanzi laumunthu komanso kagayidwe kazabwino.

Lipase amalimbikitsa kusokonekera kwa mafuta kupita ku glycerol ndi mafuta a carboxylic acid

Kuchita kwa lipase ndi bile

Kugwiritsidwa ntchito kwina kwa michere ya lipolytic kumatheka pokhapokha ndulu. Chinsinsi ichi chimathandizira kutsitsa kwa mafuta, kuwasiyanitsa ndikusintha kukhala emulsion, potero kumawonjezera kwambiri gawo la zochita za enzyme pamafuta ndikuwongolera kulumikizana kwawo, komanso kuthamangitsira hydrolysis. Kuphatikiza apo, ma asidi a bile amatha kusintha lipase yomwe imapangidwa ndi kapamba kuti ikhale yogwira, kotero kuti mamolekyulu onse amthupi omwe amalowa m'magawo am'mimba amatha kupezeka ndi cleavage mwa mitundu yosiyanasiyana ya lipases.

Gome: Mfundo zomwe zimadalira zaka za lipase

Ngati tilingalira za zofunikira za pancreatic lipase yokha, ndiye kuti mtengo wake wolondola udzakhala 13-60 U / ml.

Zisonyezo za lipase kusanthula

Kuchuluka kwa lipase m'magazi kumawonetsa mkhalidwe wam'mimba. Kuwonjezeka kwakukulu kwa kuchuluka kwa mapamba a pancreatic lipase kuwonetsa kupezeka kwa kapamba. Kuyesedwa kwa magazi kungakuwuzeni za matendawa ndi momwe mungayambire zovuta.

Mwanjira yovuta kwambiri yotupa kapamba, patatha maola eyiti, kuchuluka kwa lipase kumatha kuwonjezeka chifukwa cha khumi, ndiye kuti kukula kwake kumakhalabe mpaka milungu iwiri.

Kusanthula kwa nkhani zam'masewera a lipase ndizodziwika bwino. Kuphatikizika kwa enzymeyi kumakhala kosalekeza kwa ma pathologies ambiri: matenda a chiwindi, kukula kwa ectopic mimba, pomwe phindu la michere ina yamagayidwe amasintha.

Dokotala atha kukulemberani kafukufuku wokhudza milingo ya lipase ngati wodwala akuganiza zotsatirazi:

• pachimake kutupa kwa kapamba (kapamba). Chomwe chikuwonetsedwa kwambiri ndi kusanthula kwakukonzekera kubereka maola 48 atachokapo kwa zizindikiro za chifuwa chachikulu cha kapamba - chifukwa chake phindu la enzymeyi lidzakhala lalitali kwambiri.
• aakulu mawonekedwe a kapamba - munjira iyi ndikovuta kudziwa matenda, chifukwa pakapita nthawi yayitali, kapamba amasiya kutulutsa ma enzyme ndipo kuchuluka kwa lipase m'magazi kumachepetsedwa.
• mumps, kapena mumps, ndi matendawa, yachilendo ya lipase ikuwonetsa kutukusira kwa zotupa za parotid, ndikuwonjezereka - nthawi ya pathological process mu kapamba.

Zizindikiro za kuchepa kwa lipase komanso kuchuluka kwambiri

Popeza enzyme imayendetsa bwino kugaya zakudya zamafuta, ndikusowa kwa chinthuchi, kuperewera kwa enzymatic pancreatic kumayamba. Zizindikiro zakukula kwa mkhalidwewu ndi:

• kumva kufooka mwa wodwala,
• fetid chopondapo chamadzi mosasintha,
• kusowa kwa chakudya kapena kuchepa kwake,
• chisangalalo
• kuchepetsa thupi
• maonekedwe a nseru ndi kusanza,
• kupweteka kwam'mimba.

Ndi lipase yochulukirapo, Zizindikiro zomwezo zimawonekera, koma nthawi zambiri kutentha kwa thupi kumakwera, komwe kumakhala chizindikiro chokhudzana ndi njira yotupa (pancreatitis).

Kusanthula

Kukhazikitsa mulingo wa lipase, zopereka zamagazi kuchokera mu mtsempha ndizofunikira pakufufuza. Kukonzekera njirayi ndikosavuta:

1. Masiku 3-4 musanalandire magazi, muyenera kupewa kudya zamafuta, komanso zonunkhira, marinade ndi zokometsera.
2. Patsiku lopereka magazi kuti lisanthulike, kukana kudya ndikofunikira, mutuwo uyenera kukhala ndi mimba yopanda kanthu.
3. Ngati wodwala amatenga mankhwala mosalekeza, ndiye kuti ndi bwino kumuuza dokotala za izi kuti apeze zotsatira zodalirika. Njira yabwino ikakhala kusiya kusiya kugwiritsa ntchito mankhwalawa sabata lonse musanapereke magazi chifukwa cha lipase.
4. Kusanthula kumayenera kukonzekera maola oyambirira (mpaka 11 am).

Ndikofunika kupewa kukapereka magazi a lipase ngati patsikuli wodwalayo adayeza mayeso a X-ray.

Ngati matenda a lipase ali ofunika kuchitidwa osakambidwa chifukwa cha zovuta za wodwalayo, ndiye kuti maphunziro apadera safunika.

Zitsanzo zamagazi pakufufuzira ndi njira yosavuta komanso yopweteka kwa munthu aliyense kuyambira ali mwana.

1. Asanatenge magazi kuti aunikirane, alendo okwanira amawayikidwa pamwamba pa nsonga.
2. Pomwe amapangira magazi amapukutidwa ndi mowa, pambuyo pake singano imayikidwa mu mtsempha.
3. Mutatenga kuchuluka kofunikira pa biomaterial, maulendo osungirako amachotsedwa.
4. Malowo adakulungidwa ndi thonje ndikusindikizidwa kumtunda kuti asiye kutuluka.

Nthawi zambiri, limodzi ndi chopereka chamagazi, kutsimikiza kwamomwemonso mulingo wa amylase, enzyme yowonjezera yomwe imadziwika ndi kapamba, imapangidwanso kuti izindikire kuchuluka kwa lipase.

Zifukwa zopatuka

Kutanthauzira kwa zotsatira za kuwunika kwa lipase kudzathandiza adotolo kuti azindikire matenda ena ndikuwupatsanso chithandizo choyenera.

Kupitilira muyeso wa enzymeyi mutha kuwonetsa matenda otsatirawa:

• chitukuko cha kapamba mu pachimake gawo,
• njira yotupa mu ndulu,
• Kulephera kwa ntchito ya endocrine system,
• mumps
• zilonda zam'mimba, zilonda zam'mimba,
• kapamba,
• osakwanira impso,
• zochitika za autoimmune
• matumbo,
• gout
• kukhalapo kwa zotupa zoyipa m'mapapo,
• vuto la mtima
• kunenepa kwambiri. Kuchulukana kwambiri kwa lipase kumavumbula mtundu wina wa kapamba, chizindikiritso chadzidzidzi chomwe chimakwiyitsa impso kapena chiwindi

Kutsika kwa lipase kukuwonetsa zotsatirazi:

• mawonekedwe a zotupa m'dera lililonse kupatula ziphuphu,
• kupita patsogolo kwa kapamba mpaka gawo lamavuto,
• opaleshoni yoyeserera kapamba,
• cystic fibrosis,
• zilonda zam'mimba,
• hyperlipidemia (matenda obadwa nawo omwe kuchuluka kwa lipids m'magazi kumachulukirachulukira),
• peritonitis.

Lysosomal Acid Lipase Defence (DLLC)

Matenda ngati DLLC adayamba kupezeka posachedwa. Ndi matenda osowa awa, ma enzyme lysosomal acid lipase sapezeka m'thupi kapena ali ndi vuto lalikulu. Pali kudzikundikira kwa lipids mu maselo ndikuwonjezera kapangidwe ka cholesterol. Lysosomal acid lipase akusowa ndikuwonetsa ziwiri:

• Matenda a Wolman ndi matenda owopsa omwe amayamba chifukwa cha kusintha kwa majini komwe kumakhudza chiwindi ndi ma adrenal gland. Odwala omwe ali ndi vutoli nthawi zambiri amafa ali wakhanda,
• matenda a kudzikundikira kwa cholesterol esters, omwe amawononga osati chiwindi chokha, komanso mtima wamtima. M'magazi, zomwe zili ndi lipid zambiri zimawonedwa, atherosulinosis imayenda bwino mwa wodwala. Moyo wa wodwalayo ukhoza kukhala wautali kuposa momwe akudwala matenda a Wolman, komabe, ngakhale ali mwana, wodwalayo amayamba kuwonongeka kwa chiwindi pamlingo wina kapena wina.

• kusanza
• kutsegula m'mimba
• kutulutsa kwambiri,
• kutalika
• jaundice
• kufooka kwa thupi
• kuchepa thupi.

M'mayiko a USA ndi EU, amaphunzira kuchiza matenda a Wolman pogwiritsa ntchito njira ya enzyme, yomwe odwala omwe amalandila mankhwala a Sebelipase alpha ali ndi mwayi wokhala ndi moyo wabwinobwino.

Sebelipase alpha ndi mankhwala olimbikitsa ochizira matenda achilengedwe obwera chifukwa cha kuchepa kwa lysosomal acid lipase, makamaka matenda a Wolman

Zomwe Zimakhudza magazi a Lipase

Kuphatikiza pa matenda omwe alipo komanso odwala kwambiri, kuwonjezereka ndi kuchepa kwa zam'magazi kumatha kuchitika chifukwa chachitatu:

• kumwa mankhwala:
  • Indomethacin
  • analgesics
  • sedative
  • heparin,
• kuvulala kapena mafupa a mafupa aatali okhala ndi mafuta ochulukirapo (kuchuluka kwa lipase kumachulukitsa),
• kudya kwambiri ndi kuchuluka kwa mafuta m'zakudya (lipase yafupika).

Gome: zimayambitsa kusintha kwa lipase ndi chithandizo

Malingaliro anga, kutsatira kwambiri zakudya ndi kukana mowa kuli kutsogolo kwa chithandizo cha kapamba. Mu gawo loyipa la matendawa, kufa ndi njala ndiye njira yabwino kwambiri - mutadikirira masiku angapo pamadzi, mudzapeza zotsatira zabwino kuposa kugwiritsa ntchito mankhwala okwera mtengo. Njala imayambitsa kutupa kwadzaoneni, imasiya kupangitsa kuti kapamba azichita nawo mgaya, potero amayambitsa kubwezeretsanso gawo lomwe lakhudzidwalo. Njira yothanirana ndi njala iyenera kukhala pang'onopang'ono, pambuyo pake ndi bwino kudya zakudya nambala 5, zomwe sizimaphatikizapo zakudya zamafuta, mbale zophika ndi yokazinga ndi zokometsera, zokometsera zokometsera ndi zonunkhira. Zakudya zochepa zimalimbikitsidwa mpaka kasanu ndi tsiku, kupewa njala.

Chithandizo cha matenda

Cancreatitis yomwe yapezeka munthawi yomweyo komanso matenda ena am'mimba amathandizanso kuchiza komanso kupewa kupeana zovuta. Chithandizo choyenera ndi zakudya zimayambitsa kuchepa kwa lipase pambuyo masiku 14.

Ngati odwala awona kuchuluka kwa lipase kwa nthawi 10 kapena kuposerapo ndipo popanda kusintha pambuyo pa mankhwala, mankhwala omwe wodwalayo amawonjezerawa siabwino. Kukana chithandizo kwathunthu komanso matenda othamanga kungayambitse kudwala kwa wodwalayo.

Kupewa kwa milomo ya lipase

1. Kutsatira zakudya zoyenera, kuchuluka kwamafuta, mapuloteni ndi chakudya.
2. Kufunsidwa panthawi yake ndi dokotala kuti adziwe zizindikiro za kapamba.
3. Kukana zizolowezi zoyipa, makamaka mowa, zomwe zimakwiyitsa matendawa.
4. Kutsatira malingaliro onse a dokotala komanso kumwa mankhwala mukachotsedwa.
5. Matenda a kulemera.

Mayeso a lipase ndi chizindikiro chodziwika bwino cha matenda a pancreatic. Kuyeza kwakanthawi kumathandizira kudziwa kuyambika kwa matendawa, kutsata momwe alili komanso kuthandizira kwake.

Zambiri

Ndikofunika kudziwa kuti - lipase, yomwe imayang'anira thupi.

Ndi phula lamadzi losungunuka lamadzi. Ziwalo zingapo za anthu zimatulutsa lipase. Enzyme imathandiza:

• gawani mafuta, kuwagawa tizigawo tating'onoting'ono, kuti agwiritse ntchito pakataya chakudya,
• kuyamwa mavitamini ndi mafuta acids,
• kuchita mphamvu kagayidwe.

Enzyme yogaya chakudya imagwiritsa ntchito mafuta, triglycerides, kumasula gawo limodzi la iwo glycerol ndi asidi apamwamba kwambiri. Chifukwa cha kuthyoka kwamafuta, chimbudzi cha chakudya m'matumbo chimakhala chofulumira komanso chosavuta.

Lipase yopangidwa ndi tiziwalo timene timayamwa timatulutsa glycerin. Ndipo momwe mafuta acids amasinthidwira ndi caustic alkali.

M'mimba, kuphwanya mafuta pafupifupi sikumachitika. Amadutsa osasinthika mu duodenum ndipo amathandizidwa ndi enzyme yosungunuka ndi madzi.

Njira izi zimagwirizanitsidwa ndi metabolism ya carbohydrate, zimapereka mokwanira mphamvu ya thupi.

Zosiyanasiyana

Pali mitundu ingapo ya enzyme yogaya chakudya:

1. Pancreatic lipase imachita imodzi mwazinthu zazikulu pakugaya, kulowa mu ubale ndi madzi a m'mimba. M'matumbo, mukadali yogwira, imaphwanya triglycerides, yomwe imapangitsa kuti isamavute kudya.
2. Lipase yaying'ono yam'mimba imakhala ndi mafuta opaka, monga mkaka. Njirayi ndiyofunika kuti mafuta amwe mkaka wa m'mawere.
3. M'matumbo ang'onoang'ono, mukamakumba chakudya, mumadzaza madzi am'madzimo momwemo. Ngakhale atachotsa kapamba, mafinya amalowetsedwa ndi matumbo a m'mimba.
4. Mwa zochita zake, ma enzyme omwe amapangidwa ndi chiwindi amakhala pafupi ndi mitundu ya pancreatic. Kuphatikizika kwake kumachitika m'chiwindi, kenako enzyme imalowa yomweyo m'magazi. Polumikizana ndi makoma amitsempha yamagazi, lipase imayang'anira kuchuluka kwa lipids m'madzi am'magazi.
5. Pali mtundu wa leukocyte ndi pulmonary wa enzyme.
6. Amadziwika ndi chilankhulo kuti zimapangidwa ndi tiziwalo tomwe timatulutsa pakamwa pa ana omwe angobadwa kumene. Zimathandizira kuyamwa zigawo za mkaka wa m'mawere. Kufunika kwa izi kukazimiririka, tiziwopsezo timasiya kutulutsa chimbudzi.

Pancreatic lipase ndikofunikira. Ngati m'mimba thirakiti liyamba kugwira bwino ntchito, kuchuluka kwa mapangidwe ake m'mwaziwo kumasintha.

Kodi chizolowezi ndi chiani?

Kudziwona kuchuluka kwa enzyme pakuwunika magazi a biochemical ndikofunikira kwambiri masinthidwe a ziwalo zam'mimba akachitika.

1. Mwa ana, mulingowo umachokera ku ziro mpaka magawo 130 pa millilita imodzi yamagazi.
2. Mwa anthu akuluakulu (anthu azaka zopitilira 17) - kuchokera ku 0 mpaka 190 mayunitsi. Chikhalidwe kwa akazi ndi chimodzimodzi.

Kuwunikaku kumawonetsa gawo lokha la encyme ya pancreatic, monga momwe ziwalo zina zimakhalira m'magazi ochepa.

Pamene magazi zamankhwala amuzolengedwa zotchulidwa

Ntchito ya enzyme imatha kutsimikiziridwa ndi kuyezetsa magazi a biochemical. Mlingo wa enzyme umakhala ndi gawo lofunikira mukafuna kuzindikira moyenera.

Chiyeso cha lipase cha matenda apachifupa chimawerengedwa ngati mayeso enieni. Pancreatitis pachimake imapangitsa kuti chiwonjezeke chake chikugwirizana ndi nthawi ziwiri kapena zingapo.

Mukazindikira matenda a kapamba, muyeso wa ma enzyme awiri umayang'aniridwa. Osangokhala lipase zokha, komanso amylase ndikofunikira kudziwa zomwe zimayambitsa kuvutitsidwa kovuta. Mtundu wa chidakwa cha matendawa chimatsimikiziridwa ngati chiŵerengero cha michere iyi ndichoposa ziwiri.

Zochita za Amylase zimawonjezeka pang'onopang'ono, mpaka zimafika pachimake tsiku litatha kuukira. Mitsempha yamagazi yomwe idatengedwa kuti iwunikidwe imawunikidwa mu labotale, ndipo lipase yogwira imapezeka m'mbuyomu. Izi zimathandiza wodwala mwachangu. .

Perekani cheke cha kuchuluka kwa magazi a lipase pamene wodwalayo akuwaganizira kuti samangokhala ndi pancreatitis yokhazikika kapena yapakati. Malinga ndi izi, ma process a chiwindi mu chiwindi, chikhodzodzo chimatha kuzindikira.

Kuwunikiranso ndikofunikanso pakuwonetsetsa kuti matumbo amatsekeka, zilonda zam'mimba.

Kupenda kwa zamankhwala amuzolengedwa kumatha kudziwa kuti wodwalayo akupanga matenda ashuga a ketoacidosis, omwe amayamba chifukwa cha kufooka kwa kagayidwe kazakudya kapena kulephera kwaimpso.

Ngati pali zopatuka pantchito ya ziwalo zamkati, ndiye kuti zolemba zowunikira zikuwonetsa kuchepa kapena kuwonjezeka kwa milingo ya enzyme.

Zoyambitsa mfundo zapamwamba mwa akulu ndi ana

Lipase imatha kuwonjezeka m'magazi pamene wodwala ali ndi matenda apamba. Izi zitha kukhala mtundu wa kapamba, komanso zotupa zosiyanasiyana.

Matenda a metabolism omwe amaphatikizidwa ndi kunenepa kwambiri, shuga ndi gout, amakhudza kuchuluka kwa lipase.

Mu ana, kuchuluka kwa enzyme kumalumikizidwa ndi mamps pa kufalikira kwa matenda opatsirana pancreatic minofu.

Zomwe zimapangitsa milingo yokhala ndi lipase yayikulu kugwiritsidwa ntchito kwa mankhwala monga mapiritsi ogona, ma narcotic painkillers, indomethacin.

Pambuyo pakuvulala, maopareshoni, kuwundana, komanso munthawi yakukula kwa impso kulephera, ntchito ya enzyme imawonjezeka, koma izi sizokhudza mikhalidwe yotere ndipo sizimaganiziridwa pakuzindikiridwa.

Fupa la tubular likakhudzidwa pakavulala, kupenda kuchuluka kwa enzyme kumathandiza kupewa kukula. Zovuta za zoopsa kwambiri ndi njira zam'mapapo.

Kuzindikira koyambira kwa embolism kudzapulumutsa wodwalayo kuimfa . Chifukwa chake, kuwunikira kwa enzymatic kuyenera kuchitidwa chifukwa cha fractures pamene mafupa a tubular akukhudzidwa.

Kuchotsera kwa zotsatira za kusanthula

Kutengera mtundu wa nthendayo, index ya lipase m'magazi imasinthanso.

Ngati pancreatic edema imayamba, ndiye pang'onopang'ono, kuchuluka kwa michere kumakhala koyenera. Zimawonjezeka pang'ono panthawi ya mafuta pancreatic necrosis. Ngati chochitikacho chikuwonjezeka kupitilira katatu, ndiye kuti mawonekedwe a hemorrhagic amadziwika.

Koma ndikusintha kwa pancreatitis pachimake kukhala mawonekedwe osakhazikika, cholozera cha enzyme mu seramu chikhala chokhazikika kapena chocheperako.

Kusungika kwa kuchuluka kwa enzyme m'magazi kumachitika mkati mwa sabata limodzi kapena awiri. Ngati kutsika sikumachitika, ndiye kuti izi zikuwonetsa zovuta za matendawa.

Zolinga zamtengo wotsika

Kuchepetsa kwa enzyme kumachitika pamene ziwalo zamkati mwa munthu zimagonjetsedwa ndi kukula kwazodwala. Koma ndi zotupa mu kapamba, lipase yayikulu m'magazi imawonetsedwa.

Amayambitsa kuchepa kwa enzyme mu seramu matumbo. Mu ana, amatha kuphatikizidwa ndi matenda obadwa nawo a cystic fibrosis, omwe amakhudza tiziwalo timene timakhala m'mapapu.

Ntchito ya enzyme imachepetsedwa ndi kuperewera kwa zakudya m'thupi pamene njira za metabolic m'thupi zimasokonekera. Odwala nthawi zambiri amakhala ndi triglycerides yambiri m'magazi awo chifukwa chodya zakudya zamafuta.

Imachepetsedwa mwa odwala omwe kapamba amachotsedwa.

Momwe mungabwezeretse kuchuluka kwa ma enzyme kukhala abwinobwino

Ndikothekanso kubweretsera cholozera cha lipase pamlingo woyenera wopanga njira zamankhwala am'kati mwa ziwalo zamkati:

1. Zochizira kapamba, mankhwalawa amagwiritsidwa ntchito kuthetsa mavuto, kuthana ndi kuledzera kwa thupi. Inhibit pancreatic ntchito pogwiritsa ntchito puloteni ya enzyme zoletsa. Woopsa milandu, lota.
2. Ndi complication ya pachimake kapamba - kapamba necrosis - njira zofunika kupulumutsa wodwalayo. Chifukwa chake, njira zochizira komanso zotsika mtengo zimagwiritsidwa ntchito.
3. Ndi ma mumps, ndikofunikira kuti mupereke mankhwala ochepetsa mphamvu ya kutupa - onse omwe si a antiidal ndi mahomoni.
4. Kugwiritsa ntchito bwino kwa neoplasms kukweza mulingo wa chakudya chamagetsi m'magazi kukhala zabwinobwino.

Pambuyo mankhwala a matenda am'mimba, odwala ayenera kukayezetsa magazi kuti adziwe kuchuluka kwa ntchito ya lipase m'magazi.

Ngati pancreatitis ikukayikiridwa, dokotala amakupangira kuyesedwa kwa lipase, komwe kumatsimikiza kuchuluka kwa puloteni iyi m'magazi.

Zikondamoyo zimatulutsa lipase panthawi ya chimbudzi. Enzyme imeneyi imathandizira matumbo kugwetsa mafuta. Zikondazo zikagundika, zimabisala.

Kuyesedwa kwa lipase kumatha kuwonetsa ngati misempha ya lipase ya magazi ndi yokwera. Mulingo wokwera ungathe kuwonetsa vuto ndi kapamba.

Dokotala wanu amathanso kutsimikizira kuchuluka kwa enzyme ina yotchedwa amylase pamodzi ndi kuyesa kwa lipase. Izi zitha kupereka chidziwitso chowonjezereka chomwe chithandizira kuzindikira vuto la pancreatic.

Ganizirani machitidwe, zotsatira ndi miyambo ya lipase m'magazi, komanso zomwe muyenera kuchita ngati lipase ndi yokwezeka.

Dokotala nthawi zambiri amakupangira kuyesedwa kwa lipase yamagazi ngati munthu ali ndi vuto la kapamba.

Zizindikiro zina zimaphatikizapo:

• malungo
• chopondapo mafuta
• kusanza ndi kapena kusanza
• kupweteka kwambiri kumtunda kwa m'mimba,
• kugunda kwa mtima
• kuwonda
• kusowa kwa chakudya
• kupweteka kumbuyo.

Dokotala wanu atha kuyitanitsa kuyesa kwa amylase pamodzi ndi kuyesa kwa lipase. Zotsatira zakuyesa kwa Amylase zitha kuwonetsa ngati munthu ali ndi matenda apamba.

Miyezo ya Amylase ikhoza kuwonetsa zovuta zotsatirazi:

• kapamba kapena kutupira kwa kapamba, amene amakhala wopweteka kapena pachimake,
• kutupa kwa ndulu,
• matenda a celiac
• matenda a impso
• khansa ya kapamba.

Pambuyo pakuzindikira, dokotala amatha kugwiritsa ntchito mayeso a lipase ndi amylase kuti awone momwe wodwalayo alili.

Kodi kuwunika kwa lipase kumachitika bwanji?

Kuyesedwa kwa lipase kumachitika ngati kuyezetsa magazi kulikonse. Katswiri wa labu amakoka mtsempha wokhala ndi alendo. Kenako amasankha mtsempha, ndikuthira magawo pamalowo ndikutulutsa magazi kuchokera mu mtsempha.

Wothandizira labotaleyo ndiye kuti amatumiza zitsanzo zamagazi ku labotale, komwe milingo ya lipase imayezedwa ndikuwunikiridwa.

Nthawi yazotsatira zimadalira momwe zinthu ziliri. Funsani dokotala wanu pamene zotsatira zoyesa zakonzeka.

Momwe mungakonzekerere kusanthula?

Kukonzekera kuwunika kwa lipase yamagazi ndikochepa. Nthawi zambiri ndikofunikira kuyesedwa m'mimba popanda kudya kwa maola 8 mpaka 12, musanakayezetse magazi.

Munthu yemwe amamwa mankhwala aliwonse kapena othandizira ayenera kudziwitsa adokotala pasadakhale chifukwa zinthu zina zimasokoneza zotsatira zoyenera za mayeso a lipase. Dokotala angakulangizeni kuti musamwe mankhwala ena musanayesedwe.

Mankhwala otsatirawa angakhudze milingo ya magazi lipase:

• codeine
• kulera
• thiazide okodzeya,
• morphine.

Mitundu ya lipase m'magazi

Magawo azotsatira amapezeka malinga ndi izi:

• zaka
• mbiri yazachipatala
• njira yoyesera

Chifukwa cha kusiyanasiyana, ndikofunikira kukambirana pazotsatira ndi dokotala. Zotsatira zomwezi zitha kuonetsa vuto mwa munthu m'modzi, koma khalani mwa mtundu wina.

Ma labotale akapereka zotsatira zoyeserera, milingo ya lipase nthawi zambiri imayezedwa m'magawo pa millilita yamagazi.

Mitundu ya lipase m'magazi:

Kuchulukitsa kwa kapamba kumapangitsa kuchuluka kwa lipase m'magazi mkati mwa maola 4-8. Magawoli amatha kukhala okwera mpaka milungu iwiri.

Miyezi yambiri ya lipase imatha kuwonetsanso zovuta zina, monga impso kapena matumbo.

Miseru yokhala ndi lipase yachilendo mwadzidzidzi imatha kuwonetsa mavuto osiyanasiyana.

Kodi kukwezedwa kwa magazi lipase kumatanthauza chiyani?

Milingo yokwezeka ya lipase ikhoza kuwonetsa zinthu zingapo, monga:

• pachimake kapamba
• gastroenteritis ya gallstones, yomwe imachitika pamene kachilombo kamayambitsa kutupa m'mimba,
• matumbo
• cholecystitis kapena mwadzidzidzi kutupa kwa ndulu
• matenda a celiac
• matenda amatsenga
• khansa ya kapamba
• kulephera kwa aimpso
• mumps
• peritonitis.

Kuchulukitsa kwa lipase ya m'magazi kungayambenso chifukwa chotenga mankhwala osiyanasiyana - maantibayotiki, ma analgesics, etc.

Kutanthauzira kwa zotsatira za kusanthula ndi kuwunika kuyenera kupangidwa ndi adokotala.

Kodi kuchepa kwa magazi lipase kumatanthauza chiyani?

Lipase yotsika kwambiri imatha kuwonetsa kuwonongeka kosatha kwa maselo a pancreatic omwe amapanga lipase. Izi zitha kukhala chifukwa cha kuphwanya kwanthawi yayitali, monga:

• aakulu kapamba
• cystic fibrosis.

Komanso kuchepa kwa magazi lipase kungasonyeze:

• chotupa mu ziwalo zosiyanasiyana,
• peritonitis
• kutupa ndi mitsempha ya ndulu,
• zotupa ndi zotupa za kapamba,
• zilonda zam'mimba zopangidwa, etc.

Momwe milili ya lipase imachepera

Kuti muchepetse lipase m'magazi, ndikofunikira kuchita zochizira matenda omwe adakula.

Acute pancreatitis ndi amodzi mwa mavuto omwe amabwera chifukwa cha kuthamanga kwa magazi m'magazi. Dokotala akapeza matenda am'mbuyomu, chithandizo chitha kuphatikizaponso:

• jekeseni wa intravenous wa mankhwala
• mankhwala a ululu
• kukana kudya panthawi yoyenera, ndiye kudya kofewa.

Dokotala amathandizanso mavuto aliwonse omwe amayamba chifukwa cha kapamba, monga ma gallstones kapena calcium. Mankhwala ena amatha kuyambitsa pancreatitis yovuta kwambiri, pomwepo dokotala angasinthe mtundu wa mankhwala kapena mlingo.

Mutha kuchepetsa chiopsezo chokhala ndi pancreatitis pachimake pakudya zakudya zopatsa thanzi komanso zopewera kupewa komanso kumwa mopitirira muyeso.

Mankhwalawa atathandizira pazomwe zimayambitsa, milomo ya magazi lipase iyenera kubwerera mwakale.

Chiyeso cha lipase sichimazungulira ndipo sichingayambitse zovuta zina.

Zotsatira zakuyesa zitha kuthandiza dokotala wanu kuzindikira pancreatitis yachuma komanso mavuto ena azaumoyo omwe akukhudza kapamba wanu.

Kuzindikira ndi kuchiza pancreatitis pachimake kumayambiriro kumalepheretsa kuchepa kwaumoyo. Kuperewera kwa mankhwala a kapamba kumatha kupha.

Chakudya chovuta kulowa mthupi lathu sichingavomerezedwe ndi dongosolo la m'mimba m'njira yakeyera. M'mbuyomu, ziyenera kugawidwa m'magawo ang'onoang'ono. Enzymes zimathandizira pa izi: amylase, lipase, proteinase, yomwe imapangidwa mwachilengedwe ndi minofu. Ngati kupanga kwawo sikokwanira, dokotala atha kukulemberani zakudya zamagulu ena. Mwa kuchuluka kwa michere yazachilengedwe m'magazi, nthawi zina zimakhala zotheka kupanga zowonera za ziwalo zina, mwachitsanzo, kapamba.

Ngati lipase ndi yokwezeka m'magazi, zomwe zimayambitsa zimatha kubisika m'matenda osiyanasiyana amthupi. Koma musanatchule mtundu wazomwe zikuwonjezera kapena kuchepa kwa lipase, ndikofunikira kumvetsetsa zomwe zili zambiri, ntchito ndi chikhalidwe cha lipase mwa munthu.

Kodi lipase ndi chiyani?

Ichi ndi chakudya chamagulu amtundu wama hydrolases. Kutanthauzaku mwina sikukufotokozera zambiri. Mwachidule, lipase ndi mapuloteni omwe amapangidwa mbali zingapo za thupi lathu kuti athe kuchita mbali zingapo, kuphatikizapo:

• Kusweka ndi kupatula kwamafuta. Ili ndiye ntchito yawo yayikulu,
• Kutenga mbali pakupanga mphamvu kwa thupi,
• Kutenga nawo gawo pa mayamwidwe ena a mavitamini ndi mafuta acids,

Kodi lipase limachokera kuti?

Kutengera minyewa yomwe lipase imapangidwa, imasiyana pang'ono ndikugwira ntchito, ngakhale gawo lawo lalikulu ndikuphwanya mafuta kumakhalabe kosasinthika. Lipase amapangidwa:

Awa ndi otchedwa pancreatic lipase, nthawi zambiri amakhala ndi gawo lalikulu kwambiri m'magazi poyerekeza ndi mitundu ina.

1. Kuwala
2. Maso amkati mwa makanda.

Pankhaniyi, amalankhula za lingase lipase, gawo lake lalikulu ndikuthandizira kuthana ndi mafuta omwe amaperekedwa mkaka wa m'mawere.

Lipase yotere imayang'anira kuchuluka kwa lipids mu plasma, ndipo popanda iyo sikungatheke kuzindikira mankhwala ena (mwachitsanzo, ma chylomicrons).

Apa, lipase imalimbikitsanso kuwonongedwa kwa mafuta a tributyrin kuti apange zinthu zina zakumba.

Pancreatic lipase imakhulupirira kuti ndiyofunika kwambiri.Mwa mulingo wake, wina akhoza kuganiza kukhalapo kwa kapamba, mawonekedwe ndi zovuta zake.

Komabe, potengera kuchuluka kwa pancreatic lipase yokhayo, sikunachitike msanga kuti matenda ena alipo kapena kulibe. Kuunika wodwalayo ndikofunikira. Kuphatikiza apo, assay ya amylase (enzyme yomwe imaphwanya wowuma), yomwe imathandizanso kwambiri pakakhala matenda a pancreatic, ikhoza kulembedwa. Nkhani zina zatsatanetsatane za enzyme monga amylase zidanenedwa m'nkhani yathu ina.

Mulingo wamagazi

Ngati tikulankhula za kupatuka mobwereza, pali kuchuluka kwa kuchuluka kwa lipase, kutengedwa ngati chizolowezi.

Kufikira zaka 18, ndizovomerezeka kukhala ndi zigawo za 0-130 za lipase mu 1 ml ya magazi, kwa anthu okalamba nthawi imeneyi imakulitsa mpaka magawo a 190.

Kuchuluka kwa lipase m'mwazi mwa akazi sikusiyana ndi chikhalidwe cha abambo.

Poyerekeza ndi magazi amylase, lipase imatha kukhala yabwinobwino m'matenda ena a chiwindi, mimba ya ectopic ndi zina zowopsa, zomwe zimapangitsa kusanthula kwa lipase.

Lipase lokwezeka m'mwazi

Kwa adotolo, ichi ndi chidziwitso chofunikira chofufuzira, chomwe chingapangitse kuti mufufuzenso kapena kulandira chithandizo china. Matenda omwe mulingo wa enzyme m'magazi amawonjezeka akhoza kukhala motere:

• Pachimake kapamba
• Cholecystitis
• Matenda a Endocrine
• Cholestasis
• Mapampu
• Matenda a mtima
• Kunenepa kwambiri
• Pancreatic oncology,
• Gout
• Kutsekeka kwamkati,
• Zilonda zam'mimba kapena minofu ina
• Kumwa mankhwala angapo

Ndikofunikanso kunena kuti kuwonjezeka kwa lipase yamagazi kumayendera ndi kuvulala ndi ma fractures.

Kukula kwa kapamba sikuchitika nthawi yomweyo, ntchito ya lipase imatha kupezeka patsiku lachitatu, pomwe patsiku loyamba ndi lachiwiri lipase imachulukirachulukira. Pali zovuta zina zapadera za matenda a kapamba. Mwachitsanzo, ndi mafuta pancreatic necrosis, lipase yamagazi imakhala yokhazikika, ndipo ndi pancreatitis yovuta kwambiri, imachulukanso katatu. Acute pancreatitis imayamba msanga, ndipo lipase imayamba kuchuluka kwambiri pambuyo pa maola 2-5 atagonjetsedwa ndi gland.

Lipase kutsitsidwa ndi magazi

Chinanso chosiyanitsa ndi kuphatikizika kwa lipase pamachitidwewo ndikuchepa kwake. Kuchuluka kwa enzyme iyi m'magazi kungasonyeze chimodzi mwazinthu izi:

1. Chotupa cha khansa chachilengedwe chilichonse, kupatula chamba chokha.
2. Zakudya zopanda pake ndi mafuta ochulukirapo.
3. Gawo lachiberekero: lipids yamagazi ambiri.
4. Kusintha kwa chifuwa chachikulu cha pancreatitis.
5. Kuchotsa kapamba.
6. Cystic fibrosis.
7. Herederal hyperlipidemia.

Kukonzekera kwa enzyme

Musanapereke magazi kuti mufufuze lipase, ndikofunikira kukana mafuta, zonunkhira komanso zonunkhira kwambiri kwa tsiku. Kusanthula kumaperekedwa m'mawa pamimba yopanda kanthu.

Njira ya enzymatic yodziwira lipase ndiyofala masiku ano, koma ilipo ya immunochemical. Amasiyana mumakanidwe ndi zofunikira kwa ogwira ntchito kuchipatala.

Nthawi zina, kuwunika kwa lipase sikuchitika malinga ndi zomwe tafotokozazi, popanda kukonzekera kwa odwala ochepa. Izi zimachitika ngati pakufunika thandizo mwachangu.

Ngati mukukadali ndi mafunso okhudza lipase yomwe ili pakayezetsa wamagazi osiyanasiyana, asiye mu ndemanga.

Lipase - ndi chiyani? Mu thupi la munthu mumakhala ma enzymes omwe ndi ofunikira. Amapereka njira yachilendo yogaya chakudya, amathandizira kuti mavitamini, ma amino acid ndi michere azitha. Zonsezi ndizofunikira osati thanzi labwino, popanda zinthu izi munthu sangakhale moyo. Mmodzi wa enzyme oterewa ndi lipase.

Ntchito za zinthu za m'thupi

Mu makanda atsopano, am'milomo yonse m'thupi, lingase lipase ndiye woyamba kulowa mu masewerowa - enzyme yomwe imagwira emulsify (kusamutsa fomu yoyenera kunyamula) mafuta mkaka wa m'mawere (triacylglycerols) mwachindunji mkamwa, chifukwa chinthuchi chimapangidwa ndi tiziwalo timene timagwira pakamwa.

Thupi la ana lili ndi mawonekedwe ake:

• Kukula msanga ndi chitukuko cha thupi ndi ziwalo sizitanthauza kupangidwa kwa nkhokwe zazikulu za glycogen,
• njira yampweya ya glucose sichinapangidwebe.

Poona izi, ma triacylglycerols (nawonso ndi a triglycerides, ma triglycerols, mafuta osalowerera, mafuta owala), omwe amasiyana muzochitika zazikulu za mafuta achilengedwe, ndizomwe zimangopatsa mphamvu zokha, komanso kutentha kwa thupi la mwana.

Popeza malovu amakulu a michere omwe amachititsa kuti milomo isagundike pakamwa sipangakhalenso, komanso kuti mlingo wa triacylglycerols wozikika m'mimba ndi lipase ya msuzi wake ndi wocheperako, chinsinsi chachikulu chokhala ndi moyo watsopano chimalumikizidwa ku lumen ya gawo lamatumbo, lomwe limatchedwa matumbo ochepa , yotchedwa duodenum (lomwe ndi dipatimenti yawo yoyamba).

Ngati ntchito ya encyme ya lingual ikuphatikizidwa ndi mafuta amkaka wam'mawere, ndipo pamimba ya m'mimba ndiye chindapusa chamtundu wamafuta ambiri, ndiye (mosiyana ndi lipase ya hepatic, yomwe imagwiritsidwa ntchito pakupanga kwa VLDLPs yotsika kwambiri ndi ma chylomicrons, pancreatic gland lipase all in the pancreatic gland lipase. - mafuta omwe adalandiridwa ndi chakudya ndipo adapangidwapo kale ndi michere ya m'mimba.

Koma "mphero" yofunika kwambiri ya chimbudzi siyigwiranso ntchito yokha - pakugwira bwino ntchito kwake, pali zinthu zinanso zingapo zofunika:

• calcium ions (chifukwa pancreatic lipase ndi enzyme yodalira calcium)
• choyambirira emulsization wa edible mafuta ndi bile umatulutsidwa mu matumbo lumen ndi chiwindi.

Chowonadi ndikuti kuti "zipse" proenzyme (poyambira yopanda mphamvu) ya prolipase kupita ku pulogic ya encyme yodzaza, ndikofunikira kuyiyambitsa mu duodenum mwa zochita za bile acid, komanso colipase, imodzi mwazomwe zimapangidwa mu pancreatic madzi.

Kumvetsetsa chifukwa chake "kuyesa kwazinthu zambiri" kumapangidwa, zimathandiza kuzindikira kuti lipase ndiyofunika kwa:

• Kuwonongeka, kukonza ndi kugawa mafuta kukhala magawo awiri,
• kutsimikiza kwamagulu osakanikirana ndi mavitamini (A, K, E, D), komanso mafuta achilengedwe amaso owoneka bwino;
• kukhalabe okwanira kuchuluka kwa mphamvu yosinthana ndi plasma lipids.

Mkhalidwe wamasisitimu ambiri amthupi zimatengera mulingo wa pancreatic lipase.

Chifukwa chake, chifukwa cha kuchepa kwake, kupezeka kwa:

• dyslipoproteinemia (makamaka, lembani IA hyperlipoproteinemia),
• triglycerides owonjezera wa serum lipoproteins,
• IHD (matenda a mtima)
• xanthomas (yofalikira)
• chodabwitsa cha malabsorption (chimbudzi chamadimbidwe) cha mafuta amafuta ambiri.

Ikuwonjezeranso kuti ntchito yayikulu ya pancreatic gland enzyme imapezeka pa pk ya alkal ya 8-9 (pomwe chisonyezo cha 4-5 chimachepetsa mphamvu ya kutsekeka kwa gulcerols ya emulsified pracyl).

Chifukwa chakuti matenda angapo, ntchito ya enzyme imeneyi imachulukirachulukira (ndikulowa kwake m'magazi), zomwe zimapezeka m'madzi am'magaziwo zimatilola kuweruza kukhalapo kwa matenda amthupi ndi zikhalidwe za pancreatic gland. Chifukwa chake, zomwe zili mu enzyme m'magazi (zonse kumtunda ndi pansi) zimagwira ntchito ngati njira yodziwira mitundu yamavuto ena.

Makanema ophunzitsa pa ma enzymes:

Zifukwa Zokulitsa Mphamvu

Popeza kuchuluka kwa lipase m'magazi (malinga ndi kafukufuku wopangidwa ndi njira ya turbidimetric) ndi pafupifupi zigawo za 190 / ml kwa amuna ndi akazi achikulire, kwa ana ochepera zaka 18 - mkati mwa mayunitsi 130 / ml (ziwalo za enzymatic mu 1 ml ya magazi), kuwonjezeraku Ikhoza kuwonetsa zovuta zonse za kugaya chakudya komanso dongosolo la matenda.

Chifukwa chake, kuchuluka kwambiri m'magazi (ndi kuperewera kofanana mumimba) kumadziwika ndi:

• kapamba
• zotupa za pancreatic gland,
• matenda okalamba a ndulu,
• zovuta pachimake (magawo a biliary colic, infarction ya myocardial).

Chithunzi chomwechi chikuchokera:

• matumbo,
• peritonitis,
• mafupa kuchekedwa kapena kuvulala kwamphamvu minofu.

Zomwezi zimawonedwa ndi zochitika zadongosolo:

Zifukwa Zotsika

Zomwe zimapangitsa kutsitsa kuchuluka kwa seramu lipase ndi:

• mafuta ochulukirapo a triglyceride muzakudya zomwe amadya (zopanda chakudya, zopanda chakudya),
• zokhudza (oncological) matenda (kupatula khansa ya kapamba),
• zina, zomwe sizichitika kawirikawiri (kapena sizipezeka kawirikawiri) chifukwa.

Magazi otsika a lipase amathanso kukhala ndi:

• cholowa cham'magazi,
• ndi kusintha kwa chifuwa chachikulu cha pancreatitis chovuta.

Pomaliza, izi zitha kukhala zotsatirazi:

• cystic fibrosis,
• cystic fibrosis,
• kusowa kwa kapamba (chifukwa chakuchotsa kwake kwa ntchito).

Kodi lipase - kutanthauzira ndi mitundu

Milomo ndi michere, i.e. agologolo, zomwe ndi chita ntchito yolondola imodzi: imathandizira kuwonongeka kwa ma triglycerides (mafuta), omwe glycerin ndi mafuta acids amamasulidwa.

Malilime amapangidwa m'thupi lathu ndipo chitani njira yonse mpaka mgaya: pakamwa, m'mimba, matumbo, komanso m'chiwindi, m'magazi, m'maselo apadera (ma adipocytes omwe mafuta amasungidwa) ndi ma cell organelles (lysosomes).

Pali mitundu ingapo ya lipase, yomwe imasankhidwa molingana ndi komwe akukhala ndi cholinga chochitira.

• lilase lipase ndi malovu lipase: imayamba kuphwanya mafuta kuyambira nthawi yoyamba kugaya, i.e. m'kamwa.
• chapamimba lipase: Uperekeni mumadzi am'mimba, pomwe sing'anga ndi acidic yambiri. Mwa munthu wamkulu, imaphwanya mpaka 30% ya triglycerides yopezeka ndi chakudya, chifukwa ntchito zambiri zimachitika ndi pancreatic lipase, mu gawo lotsatira. Mwa makanda, M'malo mwake, ma lipases am'mimba ndi zilankhulo ndizogwira ntchito kwambiri, chifukwa zikondamoyo sizimagwira mokwanira.
• kapamba kapamba: Kapamba ndiye amene amapanga lipase yayikulu. Ma enzyme awa ochokera ku madzi a kapamba amalowa mu duodenum, pomwe amapanga mafuta acids, omwe amatha mosavuta kulowa m'matumbo a matumbo. Zikondazo zimapanganso co-lipase, mapuloteni ena omwe amalumikiza lipases zina ndikupanga kuti azigwira bwino ntchito.
• lipase yokhala ndi ma cell: iyi ndi puloteni yomwe imayang'anira lipolysis, i.e. kusweka kwamafuta m'maselo a adipose minofu (lipase iyi imaphatikizidwa mwachindunji mkati mwa adipocytes) kuyambitsa nkhokwezi kuti zizipeza mphamvu. Dzina la enzyme limawonetsa kudalira kwake kwapafupi ndi mahomoni monga adrenaline ndi norepinephrine, omwe amathandizira, ndi insulin, zomwe zimalepheretsa zochita za lipase kupititsa patsogolo kupangika kwa triglycerides ndi kuchuluka kwa mafuta.
• lipoprotein lipase: yomwe ili pamlingo wamakoma a capillaries komanso imayankha pamaso pa mahomoni ena. Dzinali limagwirizanitsidwa ndi zochita zenizeni za enzyme zomwe zimatengedwa kupita ku magazi.

Zilipo mitundu iwiri ya lipoprotein lipase:

• Adipose minofu lipoprotein lipase: yothandizidwa ndi insulin, imaphwanya triglycerides mu mafuta acids, omwe amadziunjikira mu adipocytes (ndiye kuti, zotsatira zake zimakhala zosemphana ndi mahaseti okhudzana ndi mahomoni).
• Zokhudza minofu ya mafupa ndi lipoprotein lipase: yothandizidwa ndi glucagon ndi adrenaline (komanso yoletsedwa ndi insulin), imakhudza ma hydrolysis a LDL triglycerides kuti apange mphamvu.

Masautso a hydrolytic michere

Ma enzymes a Hydrolytic amayendayenda m'magazi, ndiye kuti, ma lipases omwe amapangidwa pamlingo wa kapamba, izi zimakupatsani mwayi wambiri kudzera magazi kuyezetsa magazi.

Mlingo wa Lipase Siphatikizidwe ndi kuchuluka kwa mayeso a "chizolowezi", koma phunziroli limachitika ngati kapamba (kapena ma pathologies ena omwe angaphatikizidwe ndi kapamba) amakayikiridwa, akuphatikizidwa ndi zizindikiro monga kugonja, kupweteka kwam'mimba, komanso kusowa chilakolako cha chakudya.

Mfundo zam'mbuyo kuchuluka kwa magazi a lipase kumasiyana ma laboratori kupita ku labotale, koma malangizo ndi awa:

• mpaka zaka 50 - 5-58 IU / l
• wamkulu kuposa zaka 50 - 5-67 IU / l

High Lipase Amayambitsa

Miyezo yomwe ikupita pang'ono ikhoza kukhala yokhudzana ndi:

• kutukusira kwa England, zomwe zimatsogolera kubisalira kwa enzyme,
• zilonda zam'mimba, makamaka pamlingo wa duodenum, popeza m'dera lino enzyme ndiyothandiza kwambiri,
• matenda a celiac, chifukwa cha zovuta zamatumbo a malabsorption okhudzana ndi tsankho kwa gluten, kapena zambiri za malabsorption phenomena (mwachitsanzo, kuchepa kwa magazi m'thupi ngati matenda a vitamini B12),
• kulephera kwa aimpsozomwe zimapangitsa kuti ma enzyme athe kutuluka,
• ndi cholecystitis, popeza kupangidwa kwa miyala mu ndulu kapena kutupika kwake kungasokoneze gawo la bile ndi kapamba wam'mimba, zomwe zimabweretsa kutupa kwa kapamba,
• kugwiritsa ntchito mankhwala enamwachitsanzo odana ndi yotupa ndi okodzetsaamasintha kuchuluka kwa khungu, ndikulimbikitsa kutulutsa kwa lipase.

Ngati zotsalira zikuchuluka (kawiri mpaka kasanu poyerekeza ndi zomwe zimachitika), pamakhala kukayikira kwa:

• pachimake kapamba: ngati magazi ataphatikizika ndi magazi pakapita ola limodzi pambuyo povutitsidwa ndi kupweteka kwambiri pamimba ndipo amatha masiku 4 kapena kupitilira apo, kuwonjezera apo, mu chifuwa chachikulu cha pakhungu, milingo yayikulu ya lipase imalumikizidwa ndi milingo yayikulu ya amylase,
• mavuto ena apamba (samakonda khansa). Zikondazo zikaonongeka kapena kupunduka, chiwalocho chimayamba kuchuluka, motero lipase yambiri imatha "kudumphira" ndikulowa m'magazi.

Mankhwala ochepetsa magazi a lipase - omwe amayambitsa

Kutsika kwa ndende ya magazi pakhungu kumawonedwa pazochitika izi:

• aakulu kapamba: amylase ndi lipase milingo imachepetsedwa chifukwa cha kuwonongeka kwa maselo a pancreatic omwe amalephera kupanga ma enzyme,
• matenda ashuga, popeza mphamvu ya lipases imagwirizana kwambiri ndi kuchuluka kwa insulin m'magazi,
• Matenda a Crohnmomwe ntchito ya enzyme m'matumbo imakhudzidwa kwambiri chifukwa cha kutupa kwamphamvu kwa chiwalo,
• cystic fibrosischifukwa cha kusokonekera kwa kapamba.

Mitundu yotsika kwambiri ya lipase nthawi zambiri imaphatikizidwa ndi milingo yayikulu magazi cholesterol ndi triglycerides, kuthamanga kwa magazi, mitsempha ya varicose komanso zovuta zamafuta.

Magulu asinthidwe a lipase - choti achite

Mulingo wa lipase ukakhala wambiri kwambiri kapena wotsika kwambiri, adokotala amafotokozera maphunziro owonjezera kuti adziwe chomwe chimayambitsa kusinthaku (kapamba, kulephera kwa impso, ndi zina).

Komabe, pali mitundu yamakhalidwe yomwe titha kutsata pofuna kupewa, komanso yomwe imathandizira kuti mapangidwe azinsinsi a lipase.

Pankhani ya milingo yayikulu

Kuphatikiza pa mankhwalazotchulidwa ndi dokotala ngati kapamba, cholecystitis, etc. atapezeka, kusintha zizolowezi zina zodya kudya kumathandiza kwambiri.

Nayi zitsanzo:

• siyiratu kumwa zakumwa zoledzeretsazomwe zimapweteka kapamba ndi chiwindi,
• lipase yayikulu "imatidziwitsa za kuphwanya kwa mafuta, choncho kusinthana ndi chakudya kumakhala kothandiza mkulu mu fiber,
• imwani madzi ambiri (machitidwe abwino - magalasi 8-10 patsiku), chifukwa lipase ndi enzyme ya hydro-soluble ndipo imafunikira dilution.

Pankhani ya otsika lipase

Kodi muyenera kuchita bwanji ngati magazi a lipase ya magazi ndi otsika kwambiri?

• masewera olimbitsa thupi: Kuchita masewera olimbitsa thupi pafupipafupi ndi chizolowezi chabwino! Kafukufuku akuwonetsa kuti kuchita masewera olimbitsa thupi kumathandizira kuchepetsa magazi a triglycerides komanso kumathandizanso ku cholesterol.
• gwiritsani ntchito zakudya zopatsa thanzi: Mutha kupeza zowonjezera zamalonda a lipase zogulitsa zonse nyama ndi masamba. Nthawi zambiri, zowonjezera izi ndizosakaniza ma enzymes angapo (lipase + amylase + pectin +.), Kuthandizira kugaya,
• Monga ndi milingo yayitali kwambiri, kalembedwe ka chakudya ndizofunika kwambiri. Mitundu yotsika ya lipase imayambitsa zovuta kwambiri ndi chimbudzi cha mafuta, motero muyenera kuchepetsa kudya (mwanzeru, osapitirira 20 g patsiku)! Chakudya chopatsa thanzi zipatso, masamba ndi chimanga, komanso yogurt yamafuta ochepa komanso tchizi, ndi njira yabwino!

1 Kufotokozera kwa chisonyezo

Chachilendo cha ma enzyme ndikuti zimagwira ngati zothandizira zomwe zitha kulimbikitsa mawonekedwe a mgwirizano wa zinthu zofunika ndikuchirikiza. Koma nthawi yomweyo, ma enzyme omwe, omwe amapangidwa ndi thupi, samadyedwa. Momwemonso, enzyme monga lipase, yomwe imasungunuka m'madzi, imapangidwa. Lipase ndi kuphatikiza ma mamolekyulu a protein omwe amakhudza ma insoluble, amathandizira momwe iwo amathandizira, amasweka ndikugulitsa mafuta osafunikira, kusungunuka kwawo ndi kugawidwa kwawo.

Polimbikitsa njira yogaya mafuta, lipase sakhala yekha ndipo amachita limodzi ndi bile. Pamodzi ndi mafuta, lipase imasweka ndikugaya mafuta acids. Kuphatikiza apo, ma enzyme amatenga nawo mbali pokonza kutentha kwa mavitamini osungunuka monga A, E, D, ndi K. Pamodzi ndi kutentha, thupi limalandiranso mphamvu.

Lipase amatha kutulutsa milomo ya lipids, chifukwa chomwe amasungunuka. Chifukwa cha izi, mafuta acids amalowa mwachindunji mu minofu ya ziwalo zamkati ndi machitidwe.

2 Kupanga kwa enzyme

Ma enzyme omwe amafunsidwa amapangidwa osati ndi thupi limodzi, koma angapo, chifukwa amafunikira zambiri. Pofuna kukola munthu, chilengedwe chimamupatsa mawonekedwe omwe mamembala angapo amapangidwa ndi michere nthawi imodzi, monga:

Makanda, enzyme imeneyi imapangidwa kamkamwa. Izi zimatsimikiziridwa ndi kupezeka kwa gland yapadera. Zotsatira zake, mu makanda mumakhala njira ya kaphatikizidwe wa lingase lipase, yomwe imafunikira kuti imvekedwe ndi mafuta a mkaka.

Ndikofunika kumvetsetsa kuti ziwalo zamkati sizimapanga michere imodzimodzi, koma iliyonse ili ndi mtundu wake, chifukwa chomwe zinthu zomwe sizipangidwazo sizingathe kugwetsa magulu onse a mafutawa, koma zina zokha.

Mitundu itatu ya ma enzymes

Zadziwika pamwambapa kuti enzyme (kapena enzyme) lipase imapangidwa ndi ziwalo zingapo zamkati. Koma ziwalo zosiyanasiyana zimapatsa zinthu zosiyanasiyana pazinthu zomwe zimapangidwa. Amakhulupirira kuti zofunika kwambiri ndizo mamolekyulu a protein omwe amapangidwa ndi kapamba. Pancreatic lipase imakhala ndi iwo, omwe amatsimikizira kukhudzidwa kwa lipids kwathunthu.

Pancreatic lipase ikangolowa m'matumbo am'mimba, colipase imayamba kuchitapo kanthu. Ichi ndi chinthu, enzyme yomwe imatulutsa tinthu tofanana ndi pancreatic lipase. Zotsatira zake, enzyme pamafunso amayamba kutembenukira ku mawonekedwe ake atatha kuphatikiza ndi ma acid a bile. Udindo waukulu womwe enzymeyi imachita ndikuwononga mafuta osafunikira, kapena ma triglycerides, m'magawo awo. Chifukwa cha cleavage, mafuta ochulukirapo am'mafuta ndi glycerin amapezeka.

Ndipo pali kusiyana kotani pakati pa mitundu ina ya enzyme imeneyi, yomwe imasungidwa ndi ziwalo zina? Ngakhale onse amapangidwa kuti azilumikizana ndi mafuta, enzyme iliyonse imachita zamafuta amtundu wina wamafuta. Monga chowongolera kuchuluka kwa plasma lipids, hepatic lipase amachita, yomwe imagwira ntchito pamlingo wotsika wa lipoproteins.

Ma molekyulu a protein omwe amatulutsidwa ndi m'mimba amagwira ntchito mwamphamvu kwambiri pamafuta a mafuta ndikuwaphwanya bwino. Ntchito ya tiziwalo timene timatulutsa mkamwa m'molekyu atsopano a protein ndiye kuti mutha kuthyola mafuta omwe amapezeka mkaka wa m'mawere.

4 Sinthani kuchuluka kwa zinthu

Thupi limafunikira zinthu zonse zofunika kuti thanzi lake lonse m'magazi likhale labwinobwino. Izi zikugwira ntchito mokwanira pamilomo ya lipase. Ngati zomwe zili m'magazi ziwonjezereka kapena kuchepa, izi zikuwonetsa kuwonongeka kwa thanzi la munthu. Chifukwa chake, madokotala amagwiritsa ntchito izi kuti azindikire za matendawa molondola kwambiri.

Ngati mutenga enzyme lipase, ndiye enzyme iyi imawonetsa zovuta mu metabolic process. Kuzindikirika kwa kupatuka pamlingo wazomwe zili m'magazi kumatilola kuzindikira matenda omwe akuphatikizidwa ndi m'mimba. Ndipo ngati wodwalayo akudandaula za kupweteka kwam'mimba, adokotala amamuwuza kuti awonenso. Malinga ndi zotsatira za phunziroli, akuwunikira kuchuluka kwa lipase m'magazi.

Kodi kuchuluka kwa enzyme yomwe ikufunsidwa kumadziwika kuti ndiyabwino? Choyamba, zimatengera zaka za wodwalayo, ndipo chachiwiri, pamlingo wotani wa lipase lomwe latsimikizika. Amawongoleredwa pazotsatira izi, malinga ndi momwe zimakhazikitsidwa nthawi zonse:

• kwa ana, muyezo ndimakhala zomwe zimapangidwa ndimagazi mu kuchuluka kwa magawo 0 mpaka 130,
• kwa akulu, chizolowezi chimakhala chachikulu - kuyambira 0 mpaka 190 mayunitsi,
• kwa enzyme yomwe imasungidwa ndi kapamba, kuchuluka kwa magawo 13 mpaka 60 mu 1 ml ya magazi imadziwika kuti ndi njira yodziwika bwino.

Ngati mayesowa akuwonetsa kuti mulingo wa lipase ndiwokwera kapena wotsika kuposa womwe wawonetsedwa, ndiye kuti njira ya pathological ikuchitika m'thupi.

5 Kodi mtengo pamwamba umakhala wabwinobwino?

Osati muzochitika zonse pamene lipase imachulukitsidwa, ndiye kuti, imaposa zokhazikitsidwa, izi zimawonetsa matenda omwe amapezeka m'thupi. Kuwonjezeka kwa kuchuluka kwamapuloteni m'magazi kungayambitse kugwiritsa ntchito mankhwala monga Heparin kapena Indomethacin. Kugwiritsa ntchito narcotic analgesics ndi barbiturates kumathandizanso ku izi.

Mwachitsanzo, munthu akavulala, mwachitsanzo, panthawi yomwe mafupa a tubular aphulika, kuchuluka kwa ma enzymes m'magazi kumawonjezeka. Koma muzochitika zotere, kusanthula kumachitika nthawi zambiri, pokhapokha kuphatikiza kuwonongeka, matenda ena kapena kuvulala kwa ziwalo zamkati kumawonedwa. Kenako dokotalayo ayenera kuganizira kuti kuchuluka kwa lipase kungayambitse kuwonongeka, osati matenda am'mimba okha.

Zina zidzafunikira zomwe zimatsimikizira kapena kupatula matenda am'mimba. Kuphatikiza pa kuwonongeka kwa mafupa amachubu, kuwonjezeka kwa kuchuluka kwa enzyme m'magazi kumayambitsanso kuvulala kwina kwakukulu.

Chofunika kwambiri ndi mulingo womwe pancreatic lipase yopangidwa ndi kapamba amawonetsera. Koma ndizodziwika kwa iye kuti ndi kuchuluka kwa kapamba, chisonyezo cha kuchuluka kwake patsiku loyamba sichipereka chilichonse, chifukwa chimakula pang'onopang'ono. Zochita zazikulu zimatha pokhapokha patatha masiku atatu kapena anayi kuchokera pamene exacerbation yayamba.

Si matenda onse a ziwalo zamkati zomwe zingakhudze kuwonjezeka kwa kuchuluka kwa enzyme yomwe ikukhudzidwa. Zikondazo zikavutikira ndi edema, lipase sikhala yopitilira muyeso wabwino. Koma ndi hemorrhagic pancreatic necrosis, komwe ndi kupitiliza kwachulukidwe kapamba, kupindika kwake, kuchuluka kwa lipase m'mwazi kumachulukitsa katatu kapena kupitirira apo. Koma ngati pancreatic necrosis ndi mafuta, zotsatira za mayeso wamba sizowonetsa zovuta za enzyme.

Ndizabwino kwambiri ngati mayesowo adawonetsa kuti mulingo wa lipase m'magazi ndi nthawi 10 kapena kuposa. Izi zimapereka kulosera kwakusadalirika. Potere, adotolo amatenga njira zadzidzidzi kuti amachepetse chizindikirochi katatu pakadutsa masiku atatu otsatira.

Ili ndi yankho ku funso loti kuda nkhawa pamene enzyme iyi ipitilira muyeso. Inde, ndikofunika, ndipo thandizo limangofunika ndi katswiri woyenera, yemwe amadzipatsa yekha mankhwala osagwiritsa ntchito mankhwala mwanjira imeneyi. Njira ya pathological ikachitika m'thupi yomwe imatsogolera kuchuluka kwa enzyme yomwe ikufunsidwa, ntchito zake zapamwamba zimawonedwa osaposa sabata limodzi. Mlingo uwu umabwezeretseka mkati mwa masabata 1-2.

Kuphatikiza pa kapamba, milingo ya lipase imachulukanso ndi matenda otsatirawa a ziwalo zamkati mwamimba:

• matenda omwe amaphatikizidwa ndi zovuta za metabolic: matenda a shuga, gout, kunenepa kwambiri,
• peritonitis
• matumbo kulowetsedwa
• m'mimba
• intrahepatic cholestasis,
• kuvulala kwachikondwerero

Mndandanda wamatenda omwe amachititsa kuti enzyme iyi iwonjezeke. Izi zimaphatikizapo cirrhosis ya chiwindi komanso kugwiritsa ntchito molakwika mankhwala osokoneza bongo. Zochita zilizonse za opaleshoni zomwe zimakhudza njira ya metabolic zingayambitse kupanga enzyme kwambiri.

Mulingo 6 pansipa

Ngati kuchuluka kwa puloteni yomwe ili pamwambapa ndi yocheperako, ndiye kuti izi zikuwonekeranso kupezeka kwa matenda akulu mthupi la munthu. Tikulankhula za njira zotsatirazi:

• chotupa cha ziwalo zamkati zilizonse kupatulapo kapamba,
• kuwonongeka kwa kugwira ntchito kwa kapamba,
• Amawona mafuta ochulukirapo m'magazi,
• cystic fibrosis, yomwe imadziwonetsera yokha chifukwa chakuti gland ya endocrine imakhudzidwa.

Kuchepa kwa enzyme imeneyi sikuwonetsa kuti ndi matenda oopsa. Zochita zina zolakwika za wodwala iyemwini zitha kubweretsa izi. Izi zimagwira ntchito kwa iwo omwe amamwa mafuta osokoneza bongo kapena samayang'anira zakudya zawo. Ngati pali masamba otsika ndi zipatso zabwino zochepa, ndipo mmalo mwake mumakhala zakudya zama calorie ambiri, zakudya mwachangu, confectionery, ndiye kuti kuchuluka kwa lipase m'magazi kumatsika.

Kuphatikiza apo, kuchuluka kosakwanira kwa enzyme kungasonyeze mtundu watsopano wa kapamba, yemwe amayamba pachimake mpaka matenda. Ngati magazi amakhala ndi lipids yambiri, chodabwitsa chimachitika chomwe chimatchedwa cholowa cha hyperlipidemia, ndipo izi zimaperekanso chofananacho.

7 Kuyesa

Monga tafotokozera pamwambapa, kuti tidziwe kuchuluka kwa ma enzymus m'magazi omwe akuwunikira, kuwunika kofunikira ndikofunikira. Adauzidwa ndi dokotala yemwe, mwa kufunsidwa, kufufuza ndikuwerenga mbiri yachipatala, amapeza njira yoyambira. Pakadali pano, amaika patsogolo Mabaibulo ena, chifukwa izi kapena zizindikiro zina zimatha kuwonetsa njira zosiyanasiyana za pathological.

Ngati wodwala akuvutika ndi ululu wokhala ngati lamba, ndiye kuti chizindikiro chotere chikusonyeza kuti zina mwa ziwalo zotsatirazi zapsa:

• kapamba
• bile ducts
• chiwindi.

Kuphatikiza apo, kupweteka kotereku kumatha kuwonetsa kukhalapo kwa kulephera kwa impso kapena zilonda zam'mimbazi. Malingaliro oterewa amayamba chifukwa cha kutsekeka kwa matumbo aang'ono ndi chidakwa.

Kwa kusanthula, magazi amatengedwa kuchokera m'mitsempha ya wodwalayo. Ayenera kukonzekera izi, zomwe malamulo ena ayenera kutsatira, akuti:

• osachepera maola 8 mayeso asanakhale mayeso akhale chakudya chomaliza,
• Maola 12 pamaso pa njirayi simungadye zakudya zamafuta,
• Pewani kumwa mowa tsiku lisanafike mayeso,
• ndizosatheka kuchita fluorography kapena radiology, ultrasound kapena physiotherapy njira musanapereke magazi,
• osachepera ola limodzi musanapereke magazi simuyenera kusuta.

Magazi amatengedwa m'mawa pamimba yopanda kanthu. Ndikulimbikitsidwa kwambiri kuti musamwe khofi ndi tiyi, koma khalani ndi madzi ochepa. Akatswiri amati data yolakwika imatha kubweretsanso chisokonezo chamtendere komanso mwathupi. Chifukwa chake, pewani kuthamanga kwa m'mawa ndikuchita masewera olimbitsa thupi, kusakhazikika komanso mikangano.

Osati odwala omwe ali ndi matenda a ziwalo zamkati okha amafunikira kuwunikiridwa kawirikawiri kuti pakhale enzyme m'magazi. Kwa odwala omwe amachitidwa opaleshoni yachiberekero, zimafunikiranso.

Lipase ndi puloteni yapadera yomwe imayambitsa kuwola kukhala zigawo zikuluzikulu ndi kukonza mafuta m'mimba. Thupi limapangidwa ndi kapamba, matumbo, chiwindi ndi mapapu. Komanso, zinthu zimapangidwa mkamwa mwa khanda - mtundu wake. Enzyme imagwira ntchito zofunika kwambiri: imagwira ntchito mwachangu mu metabolism yamphamvu, imathandizira kuyamwa mavitamini ndi ma polyunsaturated mafuta acids. Chosangalatsa chachikulu ndi kapamba wa kapamba wobisika.

Kuzunza kwa zinthu m'magazi a munthu wathanzi kuli pafupifupi osasinthika. Mu ana ndi achinyamata kuyambira pakubadwa mpaka pomwe amafika zaka 17, kuyambira 0 mpaka 130 magawo a zinthu mu 1 ml ya magazi amatsimikiza. Mwa munthu wamkulu, mfundo zabwinobwino zimakhala m'gulu kuyambira 0 mpaka 190 magawo 1 ml. Zizindikirozi ndizofanana kwa amuna ndi akazi onse. Kutsimikiza kwa lipase level kumachitika molingana ndi zotsatira za mayeso a labotale.

The kuchuluka kwa lipase aakulu ndi pachimake kapamba amasiyana ndi chizolowezi, kotero, kusanthula kwa thunthu la thunthu m'magazi kumayikiridwa kuti aikidwe pozindikira matenda a kapamba. Kuwonjezeka kwa milingo ya enzyme kukuwonetsa kutukusira kwa kapamba.

Musanapereke kusanthula, muyenera kukonzekera bwino: kwa maola pafupifupi 12 muyenera kupewa kudya mafuta, tsabola, zakudya zamchere. Kusanthula kumachitika pamimba yopanda kanthu, magazi a venous amatengedwa.

Zizindikiro zakusanthula

Gastroenterologists adzafunika zotsatira za kafukufuku wa kuchuluka kwa enzyme m'magazi pakuwonetsa ma pathologies otsatirawa:

• The pachimake gawo la kapamba. Chodziwikiratu ndi kuyezetsa magazi, zitsanzo zomwe zimachitika patatha masiku atatu pambuyo povutikapo, panthawiyi, ndi pancreatitis yovuta kwambiri, lipase idzafika pandende yayikulu.
• Matenda a kapamba. Phunziro lalitali la kutupa m'matumbo limalepheretsa kupanga michere, motero magawo a chinthucho sanena bwino.
• Matendawa ndi "mumps." Matenda opatsirana omwe amakhumudwitsa ziwalo zina mwa odwala.

Zoyambitsa High Lipase

Mlingo wa pancreatic lipase chizindikiro umasiyana ndi chizolowezi pakuwonjezeka kwa matenda osiyanasiyana am'mimba. Komanso, kugwiritsa ntchito mankhwala ena (mwachitsanzo, barbiturates, mankhwala a analgesic) kumatha kuwonjezera zomwe zili m'thupi. Kuphatikiza apo, ma enzyme m'magazi amadzuka atalandira kuvulala kwambiri kwa minofu yamafupa.

Matenda omwe mulingo ukukula

Pancreatic lipase imakula motere:

• pachimake kapamba
• aakulu mawonekedwe a kapamba,
• kapamba
• matumbo kulowetsedwa
• matumbo,
• peritonitis
• mtundu uliwonse wa matenda ashuga
• kunenepa
• intrahepatic cholestasis,
• kukongoletsa maliseche.

Ndikofunikira kuganizira mawonekedwe a chizindikiro cha pancreatic lipase. Patsiku loyamba la kuchuluka kwa kapamba, kuchuluka kwa zinthu kumachulukako pang'ono, kukula kwakukulu kumawonedwa patatha masiku atatu.Ngati kutupa kwa kapamba kunayambitsa kukhalapo kwa edema, ndiye kuti mlingowo supita pamlingo wabwino, ndi hemorrhagic pancreatic necrosis, kugundika kwa enzyme kudzapindulidwa katatu kapena kupitirira apo.

Mu mtundu wa matendawa, enzyme yoyamba imachulukitsa pang'ono, kenako imabwezeretsa mwakale.