Kuyerekezera kwa Ampicillin ndi Amoxicillin

Benzipenicillin, yomwe ndi monobasic acid, samasungunuka bwino m'madzi komanso osakhazikika, kotero umagwiritsidwa ntchito ngati wabwino! mchere wosungunuka wa sodium, potaziyamu, ndi esters. Imagwira pazinthu zopanda kanthu zomwe zimakhala makamaka kunja kwa maselo.

Gram-cocci yokhala ndi cocci ndi coli imazindikira kwambiri mchere wa benzylpenicillin sodium, makamaka pneumococci (mpaka 95% ya zovuta), hemolytic ndi pyogenic streptococci. Komabe, benzylpenicillin imagwira pa 10% yokha ya Staphylococcus aureus tizilombo, ndipo epidermal staphylococcus imakana. Enterococci nthawi zambiri sagwirizana ndi penicillin

Ndi kuyambitsa kwa IM, mankhwalawa amalowetsedwa mwachangu ndikuchotsedwa msanga m'thupi. Ikamamwa, imawonongeka posachedwa ndi ma penicillinases a matumbo. Ndiosakhazikika m'malo okhala acidic, kotero amangogwiritsidwa ntchito ngati makolo. Ambiri achire ndende ya mankhwala a m'magazi amatha maola 3-4.

Kuchuluka kwa benzylpenicillin m'magazi kumatsimikiziridwa ndi boma la chiwindi ndi impso. Ndi matenda aimpso opuwala | (mwachitsanzo, odwala omwe ali ndi anuria) T1 / 2 amafika maola 4-10, ndipo kwa iwo omwe akudwala matenda a chiwindi amatha kutalika mpaka maola 16-30. Benzylpenicillin amalowa mu minyewa yonse yamadzimadzi ndi ziwalo za thupi kupatula ubongo, minyewa yamaso, ma serous ndi ma membrane a khungu.

Mlingo wa kumasulidwa kwa mankhwalawa zimatengera mtundu wa njira, momwe makonzedwe ake amafotokozera wodwala. Kuchotsa mwachangu m'thupi kumaphatikizapo kufunika kwa jakisoni pafupipafupi kuti magazi azikhala mozama mokwanira. Kuti athetse vuto ili, mankhwalawa amapangidwa omwe amakhala ovuta kupukusa komanso kuyamwa pang'onopang'ono, ndikupereka mphamvu yayitali.

Ambiri achire mlingo umodzi wa parenteral makonzedwe a benzylpenicillin 1 miliyoni, tsiku lililonse - 6 miliyoni. Itha kuwonjezereka mpaka mamiliyoni 20 kapena kuposa.

Muyenera kupewa kusakaniza mayankho a penicillin ndi ma acid, ma alkali, alcohols, potaziyamu permanganate, hydrogen peroxide.

Masewera ovuta kwambiri, penicillin amatumizidwa iv mu yaying'ono-jet kapena kulowerera m'madzi osungunuka a jekeseni kapena isotonic sodium chloride solution. Powonjezera zinthu zina zamankhwala munjira yovomerezeka sikovomerezeka. Anayambitsidwa mu mtsempha 1-2 kawiri pa tsiku limodzi ndi kukhazikitsa minofu

Kutengera ndi kuopsa kwa matenda opatsirana, kuchuluka kwa chithandizo cha penicillin kumayamba masiku angapo mpaka miyezi iwiri kapena kupitilira apo. Kugwiritsa ntchito benzylpenicillin kukuwonetsedwa pazochitika zonse zakupezeka kwa pathogen. Mankhwala amakhalabe antiotic mankhwala osokoneza mankhwalawa chifukwa cha tizilomboti. Ndi endocarditis, kutsimikizika kwa kudziwa kwa pathogen kwa benzylpenicillin kumayesedwa kuvomerezedwa.

Contraindies: mbiri ya chifuwa cha penicillin, mphumu ya bronchial.

Mchere wa Oxacillin

• Ikutanthauza ma penicillin opanga pang'ono. Malinga ndi mawonekedwe a antimicrobial action, mankhwalawa ndi ofanana ndi methicillin. Amamwa kwambiri pakamwa, kupindika kwake kumadalira chakudya, chifukwa chake ndibwino kumwa oxacillin pamimba yopanda kanthu.

The achire ndende ya mankhwala mu magazi kumatha 3 mawola kumwa 0,5 ga pakamwa ola limodzi pamaso chakudya kapena maola awiri itatha.

Mayankho aubwino wa makolo amakhala akugwira ntchito masiku 9 kapena kupitirira. Oxacillin amalowa m'magulu osiyanasiyana a minyewa monga penicillin. Ndi kuyambitsa / m, kuchuluka kwa oxacillin m'magazi ndiwokwera kuposa momwe amamwa.

Amayikidwa mu / mu kapena / m 2-3 g komanso pamwamba 4-6 pa tsiku.

Ampicillin ali ndi mawonekedwe osiyanasiyana ochitapo kanthu, makamaka ma gram-negative microflora amawadziwa. Mankhwala amawonongeka ndi staphylococcal penicillinase, koma amakhalanso kukana kwa asidi mukamamwa pakamwa. Mwa mphamvu yake pazomera zabwino za gramu, imagwira ntchito kwambiri kuposa penicillin, koma imaposa methicillin ndi oxacillin, tetracycline ndi chloramphenicol. Ampicillin ndiwogwira kwambiri kuposa tetracycline ndi chloramphenicol motsutsana ndi hemophilic bacillus, proteina, shigella, enterococci, komanso Escherichia coli. Mphamvu ya antibacterial ya ampicillin imalimbikitsidwa ikaphatikizidwa ndi aminoglycosides ndi oxa-cillin. The bioavailability wa ampicillin pamene kumwedwa kuchokera 40 mpaka 60% ndipo zimatengera mkhalidwe wamatumbo.

Kutengera kinetics ya mankhwalawa (kuchuluka kwake mkodzo ndi bile), ndi matenda a urogenital komanso matenda amtundu, kugwiritsa ntchito ampicillin mkati kuyenera kuganiziridwa ngati njira yosankhira yomwe imatsimikizira kukhazikika kwa magazi. Mukakonza regimen ya chithandizo, ndikofunikira kuyerekezera kuchuluka kwa maantibayotiki m'magazi ndi zomwe MP / C imayang'anira pazosankhidwa. Ampicillin alibe nephrotoxic kwenikweni.

Zochizira matenda oyambitsidwa ndi non-hemolytic streptococcus, pneumococcus, meningococcus ndi hemophilic bacillus, omwe amakhudzidwa kwambiri ndi ampicillin, kugwiritsidwa ntchito kwake m'magazi sikungadutse 1 μg / ml, womwe ndi 2 g, kawirikawiri 4 g patsiku.

Mlingo wapamwamba wa mankhwalawa umalekeredwa bwino, popanda kupezeka kwa poizoni mkati mwa miyezi 1-1,5 komanso ngakhale utali wocheperako.

Ampicillin (m'mapiritsi kapena mapiritsi) amatumizidwa pakamwa pa 0,5 g maola 4 aliwonse aliwonse. Mlingo wa tsiku ndi tsiku ndi 2-4 g, milandu yoopsa - mpaka 10 g kapena kupitilira. Ndi kuyambitsa / m - 0.5 g pambuyo pa maola 4-6, mlingo wa tsiku ndi tsiku ndi 1-Zg.

Kuchepa kwambiri komanso kusapezeka kwa vuto la bongo kumapangitsa kuti munthu azigwiritsa ntchito ampicillin popanda ziletso zina zapadera popewa matenda aimpso. Komabe, dongosolo la mankhwalawa limakonzedwa, kuchepetsa mlingo wa mankhwalawa kapena kuwonjezera nthawi pakati pa oyang'anira. Ndi yotsalira wa nayitrogeni 80 mg, mlingo wa mankhwalawo umachepetsedwa mpaka 2/3, ndipo woposa 80 mg% - mpaka 1/3 tsiku lililonse.

Tsankho, Hypersensitivity kuti penicillin, aimpso kuwonongeka.

• Malinga ndi mawonekedwe a antibacterial, ampicillin ali pafupi ndi Amoxicillin, koma ntchito yake yolimbana ndi mabakiteriya achilengedwe imakhala yochulukirapo nthawi 5-7. Mankhwala olimbana ndi mankhwalawa amamwa bwino kwambiri ngati amamwa pakamwa ndikugawa bwino m'ziwalo ndi minyewa.

Mlingo umodzi wa amoxicillin ndi 0,25-0,5 g pamlomo uliwonse wa ana 8, kwa ana, tsiku lililonse ndi 20-40 mg / kg katatu.

Mukumwa Mlingo wofanana wa amoxicillin m'magazi ndi wokulirapo kuposa kawiri kuposa kuchuluka kwa ampicillin. Ma pharmacokinetics a mankhwalawa sasintha malinga ndi kuchuluka kwa chakudya.

Kuyerekeza mawonekedwe a ampicillin ndi amoxacillin

Feature

Amoxicillin

Ampicillin

Mlingo

Zokhudza pakamwa

Zokhudza pakamwa komanso pa uchemberera

Mafuta am'mimba (%)

Mphamvu ya chakudya

Sizikhudza

Amachepetsa kuyamwa

Kuzungulira kwamikodzo

Kwambiri kwambiri

Pamwamba

Kulimbikitsidwa ku Sputum

Wokwezeka kapena wolimbikira

Zabwino kapena zochepa

Ntchito yolimbana ndi penicillin zosagwira staphylococci

Zotsatira zoyipa

Matenda ofatsa

Kutsegula m'mimba, zotupa

Wowoneka bwino ali pafupi ndi carbenicillin, piperacillin akugwira ntchito motsutsana ndi Klebsiella, enterobacteria, Neisseria, hemophilic ndi Pseudomonas aeruginosa. Mitundu yambiri ya Pseudomonas aeruginosa ndi mabakiteriya oyandikana nawo amakhalabe ndi chidwi ndi piperacillin: ntchito yake imakhala yokwera maulendo 8 kuposa ntchito ya carbenicillin. Komabe, chidwi chake cha zovuta zogwiritsa ntchito carbenicillin cha Pseudomonas aeruginosa ndichotsika kwambiri. Beta-lactamases opangidwa ndi Staphylococcus aureus, ndi mtundu wa TEM, OXA, ndi CAPB wa mabakiteriya osagwiritsa ntchito gramu amawononga piperacillin. Ndi kugonjetsedwa ndi zochita za cephalosporinases.

Piperacillin imayendetsedwa mu / mu kapena / m. Ndi pa / kumayambiriro kwa bolus ya 2, 4, 6 g ya mankhwala pambuyo pa mphindi 30, kuchuluka kwambiri mumagazi kumatsimikiziridwa - 300, 4U ndi 775 μg / ml, motero, stationary - 42 μg / ml. Ndi kuyambitsa / m, kuphatikiza kwakukulu kumafikiranso patatha mphindi 30, koma ndi 40 μg / ml.

Ndi kulephera kwa aimpso, T1 / 2 piperacillin imawonjezeka: ndi zolimbitsa - 2, kwambiri - 5-6. Mwa ana obadwa kumene komanso odwala okalamba, T1 / 2 kutalika, ndipo chiwonetsero chonse chimachepa. Ndi mapuloteni a seramu, mankhwalawa amamangidwa mpaka 16-20%. Imagawika bwino ziwalo komanso minyewa, kuphatikizapo mtima, imadziunjikira mu ndulu kwambiri (mpaka 3-4 μg / ml), imalowa bwino kudzera mu magazi ndi chotchinga cha mu mtima mwa odwala omwe ali ndi meningitis.

Kugwiritsa ntchito mphamvu kwa piperacillin kuphatikiza maantibayotiki ena odwala omwe ali ndi zotupa ndi neutropenia ndikofanana ndi zomwe pogwiritsa ntchito cefotaxime ndi amikacin kapena moxolactam ndi amikacin. Mu monotherapy pochiza matenda oopsa a bakiteriya, zotsatira za piperacillin zimawoneka zofanana ndi ceftazidime.

Zotsatira zoyipa: thrombophlebitis (4%), hemorrhagic diathesis (17.2%), leukopenia (4%), eosinophilia (5-6%), wosakhalitsa hyper-Fermentemia (2.3%).

Khalidwe la Ampicillin

Chofunikira chachikulu ndi pawiri wa dzina lomweli. Kuphatikiza apo, zida zina zothandizira zimapezekanso pakuphatikizidwa. Opanga ndi makampani aku Russia (mwachitsanzo, Synthesis).

Ampicillin ndi Amoxicillin ali ndi zochitika zambiri ndipo amalimbana ndi mitundu yambiri ya tizilombo tating'onoting'ono.

Mitundu ingapo yomasulira yapangidwa:

Mapiritsi Chidutswa chimodzi chili ndi 0,25 g ya mankhwala othandizira.
Makapisozi Mu chidutswa chimodzi, 0,25 g ya mankhwala othandizira alipo.
Kuyimitsidwa 5 ml muli 0,25 ga pazomwe zimagwira.

Ampicillin ndi amodzi mwa othandizira kwambiri antibacterial. Imalepheretsa njira yopanga makoma a maselo a cell mu mabakiteriya. Mankhwalawa amagwira ntchito zamagulu omwe ali m'gulu la cocci. Izi zikugwira ntchito kwa staphylococci, streptococci, gonococci, meningococci, pneumococci.

Mankhwalawa amathandizira mabakiteriya ambiri opanda gramu. Mwachitsanzo, E. coli, enterobacteria, salmonella, ndi zina zotere. Koma mankhwalawa sathandiza pa zolengedwa zomwe zimapanga penicillin, popeza ampicillin amawonongeka chifukwa cha zomwe amachita.

Kuchuluka kwa gawo logwira ntchito m'magazi kudzakwaniritsidwa maola ochepa atatha kugwiritsa ntchito mankhwalawa. Hafu ya moyo ili pafupifupi maola awiri. Thupi limachoka m'thupi ndi ndulu ndi mkodzo. Mankhwala amawonedwa ngati oopsa. Samadzikundana m'thupi la munthu. Chifukwa cha izi, amaloledwa kutengedwa pamiyeso yayitali kwa nthawi yayitali.

Ampicillin amathandizira mabakiteriya ambiri opanda gramu.

Mankhwalawa amapatsidwa mankhwala ochizira matenda omwe amakhudzidwa ndi ampicillin. Zizindikiro zogwiritsidwa ntchito ndi motere:

matenda a kutupa kwa zigawo zam'munsi za kupuma, komanso matenda amphuno, pakamwa, pharynx, makutu (amagwiritsidwa ntchito ndi chibayo, bronchitis, tonsillitis, pharyngitis, sinusitis, otitis media, tonsillitis, chimfine.
urological pathologies okhala ndi njira yotupa (monga urethritis, cystitis, pyelonephritis, prostatitis, gonorrhea, etc.),
matenda azamankhwala oyambitsidwa ndi matenda,
njira yotupa yopatsirana mu bile ducts (imagwira ntchito ku cholangitis ndi cholecystitis),
matenda opatsirana a m'matumbo (matenda oterewa amaphatikizapo gastroenteritis, kamwazi, enterocolitis, salmonellosis, typhoid, etc.),
Kutupa kwa khungu ndi minofu yofewa yomwe imayambitsidwa ndi matenda,
endocarditis
rheumatism
mapa,
malungo ofiira,
meningitis
peritonitis
sepsis.

Contraindication ndi zoyipa

Aliyense tsankho kwa yogwira zigawo zikuluzikulu za mankhwala. Opanga amazindikira mosamala pakugwiritsa ntchito Amoxicillin, kwa anthu omwe akudwala matenda oopsa a chiwindi ndi impso. Simalimbikitsidwa kuti mugwiritse ntchito kutentha kwambiri, kuzizira, komanso kuwonjezeka kwa ma lymph node.

Kugwiritsa ntchito pa nthawi ya pakati kumachitika pang'onopang'ono moyang'aniridwa ndi dokotala.

Zovuta zina zimaphatikizira chifuwa, kufiira khungu, kuzimiririka, kuyabwa, edema ya Quincke. Chida chimayambitsa kutupa kwa mucous nembanemba (mucinitis), profuse lacrimation (conjunctivitis), kumakwiyitsa kupweteka kwapafupipafupi, nthawi zina, kungayambitse mantha anaphylactic.

Kodi pakati pa ampicillin ndi amoxicillin ndi chiyani?

Mankhwalawa ndi atsogoleri osagulitsa mumunda wawo. Adziwonetsa okha ngati njira yothandiza yolimbana ndi matenda osiyanasiyana ndi tizilombo tating'onoting'ono.

Ndi omwe ali mgulu limodzi la maantibayotiki omwe ali ndi zowononga zosiyanasiyana, ndi ma pinicillin opangidwa ndi theka. Zogulitsa zonsezi zimakhala ndi zofananira pakugwiritsa ntchito, ndizosavuta, zotsika mtengo komanso zopezeka mosavuta.

Kodi pali kusiyana kotani?

Kusiyana pakati pa Ampicillin ndi Amoxicillin ndiko mbiri yopanga mankhwala. Chowonadi ndi chakuti Ampicillin adapezeka zakale kwambiri, ndipo tizilombo tambiri timatha kusintha ndikulimbana ndi chitetezo cha antibayotiki. Chifukwa chake, madokotala akugwiritsa ntchito Ampicillin mocheperako.

China chomwe chimasiyanitsa ndikuwoneka kwakukulu kwa zotsatira za Amoxicillin pazinthu zachilengedwe. Kutengera ndi gulu la zinthu za hydroxyl, mankhwalawo amalowa m'magazi mwachangu kwambiri, zomwe zimakupatsani mwayi wopanga zinthu zomwe zimagwira m'magazi, ndikupatsanso chidwi.

Kutengera zomwe tafotokozazi, ndi bwino kunena kuti kugwiritsa ntchito Amoxicillin kumakhala kothandiza kwambiri. Ichi ndi mankhwala opita patsogolo kwambiri, omwe kulandiridwa kwake kumaloledwa ngakhale kwa ana osakwana zaka ziwiri. Amoxicillin alibe contraindication kutchulidwa, amavomerezedwa bwino ndi thupi ndipo angagwiritsidwe ntchito onse mu mawonekedwe a piritsi komanso ngati jakisoni. Kuphatikiza apo, kumwa Amoxicillin kumaloledwa panthawi yokhala ndi pakati komanso nthawi yotsekemera.

Ngati mankhwalawa ndiwotalikirapo, ndibwino kupatsa chidwi ndi Amoxicillin. Ndi kugwiritsa ntchito nthawi yayitali kwa Ampicillin, kukula kwa zozizwitsa kungatheke. Zodabwitsazi zimachitika pamene ma tizilombo tosavomerezeka amathandizira pazochitikazo, ndipo motsogozedwa ndi malo ankhanza, amayamba kupanga zotchinga ndikuchulukitsa pa liwiro lalikulu, potero amachepetsa kukana kwa thupi ku matenda oyambira.

Malangizo ogwiritsira ntchito Ampicillin ndi mlingo

Musanayambe chithandizo, kuyezetsa koyenera kuyenera kuchitidwa kuti muzindikire tizilombo tating'onoting'ono tomwe timayambitsa matendawa ndikuwunikira mphamvu ya ampicillin.

Mlingo umayikidwa payekhapayekha, poganizira kuopsa kwa matendawa, malo omwe matendawa akumva komanso kuzindikira kwa tizilombo toyambitsa matenda.

Mapiritsi ndi kuyimitsidwa ayenera kumwedwa pakamwa, kutsukidwa ndi madzi, osasamala chakudya.

Mlingo umodzi wa akulu akamwedwa ndi 250-500 mg. Mlingo wa tsiku ndi tsiku ndi 1-3 g .Pamwamba kwambiri ndi 4 g patsiku.

Mlingo wa tsiku ndi tsiku wa ana ndi 50-100 mg pa 1 kg ya kulemera kwa thupi. Ndi thupi lolemera zosakwana 20 makilogalamu, 12,5-25 mg pa kilogalamu 1 ndi mankhwala. Mlingo wa tsiku ndi tsiku umagawidwa mu 4 waukulu.

Kutalika kwa maphunzirawa kumatengera kuopsa kwa matendawa komanso kutha kwa mankhwalawa.

Kukonzekera kuyimitsidwa - onjezerani madzi mu vial m'botolo mpaka zoopsa ndikugwedezeka bwino. Kuyimitsidwa okonzedweratu ndikokhazikika kwa kutentha kwa masiku 14. Musanagwiritse ntchito iliyonse, kuyimitsidwa kuyenera kugwedezeka. 5 ml ya kuyimitsidwa okonzeka (1 scoop) ali ndi 250 mg ya ampicillin.

akhanda kuyambira mwezi umodzi - kulemera kwa 150 mg / kg /,
mpaka chaka 1 - kutengera 100 mg / kg kulemera kwa thupi patsiku.
kuyambira zaka 1 mpaka 4 - 100-150 mg / kg patsiku la thupi patsiku.
ana opitilira zaka 4 zimapatsidwa 1-2 g patsiku.

Mlingo wa tsiku ndi tsiku umagawidwa mu Mlingo wa 4-6.

Kutalika kwa chithandizo kumatengera kuopsa kwa matendawa (kuyambira masiku 5 mpaka 2 mpaka 2 mpaka 2 mpaka sabata), komanso kwa miyezi ingapo.

Ndi parenteral intramuscular and intravenous flow or Drip, limodzi mlingo wa akulu ndi 250-500 mg. Mlingo wa tsiku ndi tsiku ndi 1-3 g .. Ngati matenda akulu, mankhwalawa amawonjezereka mpaka 10 g kapena kupitilira.

Kwa akhanda opitilira mwezi umodzi, mlingo wa tsiku lililonse wa 100 mg pa kilogalamu imodzi ya kulemera kwa thupi. Ana a mibadwo ina amapatsidwa 50 mg pa kilogalamu imodzi. Pankhani ya matenda oopsa, mlingo umakulitsidwa. Mlingo wa tsiku ndi tsiku umagawidwa jakisoni 4-6 maola aliwonse a 4-6. Kutalika kwa mankhwalawa ndi jakisoni wamitsempha ndi masiku 7 mpaka 14, ndi mtsempha wa magazi - masiku 5-7. Malinga ndi umboni wa wodwalayo amatha kuthandizira jakisoni wa mu mnofu.

Kukonzekera yankho la jakisoni wa mu mnofu, zomwe zili mkati mwa vial zimasungunuka mu 2 ml ya madzi a jekeseni.

Kuti akonze yankho la kulowetsedwa kwa mtsempha wa magazi, muyezo umodzi wa mankhwalawa (osaposa 2 g) umasungunuka mu 5-10 ml ya madzi a jakisoni kapena isotonic sodium chloride solution.

Kuyambitsa kumachitika pang'onopang'ono kwa mphindi 3-5 (1-2 g kwa mphindi 10-15). Ngati mlingo umodzi upambana 2 g, mankhwalawa amaperekedwa kudzera mu mtsempha wa magazi.

Zotsatira zoyipa

Ampicillin akhoza kuphatikizidwa ndi zotsatirazi zoyipa:

Thupi lawo siligwirizana monga: kuyabwa, rhinitis, conjunctivitis, urticaria, exermative dermatitis, erythema multiforme exudative. Si kawirikawiri momwe mtundu wa edincke's edema komanso anaphylactic mantha,
Minyewa yam'mimba: mkamwa owuma, nseru, kusanza, kupweteka m'mimba, kutsekula m'mimba, dysbiosis yamatumbo, gastritis, stomatitis, kusintha kwa kukoma,
Kuwonetsedwa kuchokera mu dongosolo la hepatobiliary ndi chiwindi: cholestatic jaundice,
Kuchokera pakatikati kwamanjenje: mutu, neuropathy, kugwedezeka, kugwiritsidwa ntchito (mutagwiritsidwa ntchito muyezo waukulu).

Zomwe zimachitika mderalo zimatheka ndi jakisoni wamkati mwa njira yolowera, ululu pamalowa.

Ampicillin amatsutsana milandu zotsatirazi:

ndi chidwi chachikulu cha penicillin, cephalosporin, carbapenem,
ndi lymphocytic leukemia, matenda mononucleosis.

Ndi kulephera kwa chiwindi, mankhwalawa amagwiritsidwa ntchito pofufuza momwe amapangidwira m'magazi a magazi. Ngati mwadzidzidzi, umagwiritsidwa ntchito pa mphumu ya bronchial, hay fever ndi zina zomwe sizigwirizana ndi matenda.

Mosamala, Ampicillin ayenera kumwedwa ndi kulephera kwaimpso, kutenga pakati, ana osakwana chaka chimodzi.

Zizindikiro zosokoneza bongo - kuwonetsera kwa poizoni wamkati mwa mtima

Chithandizo - chapamimba chapamimba, makala othandizira, mankhwala a saline, mankhwala osungirako madzi amagetsi komanso amodzi. Amachotseredwa ndi hemodialysis.

Ma analogi a Ampicillin, mtengo pama pharmacies

Ngati ndi kotheka, mutha kusintha Ampicillin ndi analogue yogwira ntchito - awa ndi mankhwala:

Posankha analogi, ndikofunikira kumvetsetsa kuti malangizo ogwiritsira ntchito Ampicillin, mtengo ndi kuwunika kwa mankhwala omwe ali ndi zotsatira zofananira sizikugwira ntchito. Ndikofunikira kupeza upangiri wa dokotala komanso kuti usasinthe popanda mankhwala.

Mtengo wa mapiritsi mumafakisi ku Moscow kuchokera ku ruble 19.

Moyo wa alumali ndi zaka zitatu. Sungani pamalo owuma, amdima pamtunda wa 15 ° C mpaka 25 ° C.

Ampicillin ndi mankhwala opha tizilombo tating'onoting'ono tomwe timayambitsa matenda enaake ndipo timagwiritsidwa ntchito pochiza matenda angapo omwe amayambira bakiteriya.

Kutulutsa mawonekedwe ndi kapangidwe kake

Ampicillin wa mankhwala akupezeka mu mawonekedwe a mapiritsi, makapisozi ndi ufa pokonzekera kuyimitsidwa. Mapiritsi ndi makapisozi amapangidwa mu 0.25 g iliyonse.Phukusi limodzi lili ndi mapiritsi 10 kapena 20 amtundu woyera wokhala ndi mawonekedwe a cylindrical. Mankhwalawa amtundu wa ufa ali ndi mtundu woyera ndi tint wachikasu. Imakoma kukoma ndipo imakhala ndi fungo linalake. Ufa umapezeka m'mitsuko yagalasi 60 ya lalanje.

Mumitundu yonse ya Ampicillin, chophatikiza chophatikizika ndi ampicillin trihydrate. Piritsi limodzi lili ndi 0,25 g ya mankhwala othandizira, komanso othandizira mawonekedwe a wowuma, talc, calcium stearate ndi magnesium stearate.

5 ml ya kuyimitsidwa okonzeka kugwiritsa ntchito Ampicillin ufa uli ndi 125 mg ya ampicillin trihydrate ndi zotsatirazi:

Silicon diamondi kolloidal,
Sodium carboxymethyl cellulose,
Sodium citrate amadzimadzi,
Ponceau 4R (E124),
Sodium benzoate (E211),
Kubweza
Kukoma kwa Cherry.

Zisonyezero zakugwiritsa ntchito Ampicillin

Malinga ndi malangizo a Ampicillin, mankhwalawa amapangidwira zochizira matenda osiyanasiyana obwera chifukwa cha microflora yovuta. Zina mwa izi ndi matenda opatsirana a kupuma thirakiti:

Malinga ndi malangizo a Ampicillin, mankhwalawa amagwira ntchito pachimake komanso matenda opatsirana am'mimba, kuphatikizapo cystitis, cholecystitis, pyelitis, salmonellosis ndi ena.

Malinga ndi malangizo a Ampicillin, mankhwalawa amagwiritsidwanso ntchito pochiza matenda otsatirawa:

Khutu, mphuno ndi mmero matenda
Meningitis
Scarlet fever,
Endocarditis
Khungu ndi matenda ofewa am'mimba.
Septicemia
Rheumatism
Matenda a Odontogenic
Sepsis
Mangochika
Gonorrhea

Mlingo ndi makonzedwe a Ampicillin

Ampicillin m'mitundu yonse ayenera kumwedwa theka la ola kapena ola limodzi asanadye. Mlingo wa mankhwalawa umakhazikitsidwa payekhapayekha kwa wodwala aliyense, kutengera kuuma ndi mawonekedwe a matendawa, komanso kuganizira malo omwe matendawa ali ndi matenda.

Mlingo umodzi wa mankhwalawa mapiritsi a akulu ndi 250-500 mg. Mlingo wa tsiku ndi tsiku ndi 1-3 g. Kwa ana olemera zosakwana 20 kg, mlingo wa tsiku lililonse wa Ampicillin ndi 12,5-25 mg / kg, ndipo kwa ana olemera kuposa 20 kg ndiye 50-100 mg / kg. Monga lamulo, tsiku lililonse mlingo wa mankhwalawa umagawidwa mu 4 waukulu.

Kukonzekera kuyimitsidwa, 62 ml ya madzi owiritsa amathiridwa mu vial ndi mankhwalawa ndikugwedezeka kwathunthu. Kwa odwala okulirapo, mlingo wamba wa Ampicillin mu mawonekedwe a ufa ndi 500 mg maola 6 aliwonse.

Nthawi zambiri, kuphatikizapo chibayo, bronchitis, ndi matenda osiyanasiyana amtundu wamatumbo ndi m'mimba, mlingo wa 500 mg 4 pa tsiku umagwiritsidwa ntchito. Ndi chinzonono, 2 ga mankhwalawa nthawi zambiri amatengedwa 1 nthawi patsiku.

M'matenda ena opatsirana, pangafunikire kuwonjezera kuchuluka kwa Ampicillin mwa mawonekedwe a kuyimitsidwa. Ngati zimachitika kwambiri mawonekedwe, mlingo wa mankhwalawa kwa achikulire akhoza kukhala 3 g patsiku.

Mlingo wa tsiku ndi tsiku wa Ampicillin ufa wa ana osakwana zaka 3 ndi 100-200 mg / kg thupi. Iagawidwa pawiri. Kwa ana okulirapo kuposa zaka 3, mlingo umakhala motere: 50-100 mg / kg kulemera kwa thupi, logawidwa ndi 4.

Zotsatira zoyipa za Ampicillin

Kugwiritsa ntchito Ampicillin nthawi zina kumatha kubweretsa zotsatirapo zoyipa. Ena mwa iwo ndi awa:

Edincke's edema,
Zotupa pakhungu ndi kuyabwa,
Conjunctivitis
Erythema multiforme,
Rhinitis
Dermatitis yapadera,
Urticaria.

Nthawi zina, ampicillin angayambitse kupweteka kwam'mbuyo, mantha anaphylactic, eosinophilia, ndi malungo. Nthawi zina mankhwalawa amayambitsa zotsatira zoyipa zamagetsi monga kugaya mseru, kusanza, kuchuluka kwa mpweya m'matumbo ndi m'mimba.

Kugwiritsa ntchito ampicillin kungayambitsenso:

Stomatitis
Anemia
Chikalinda,
Leukopenia
Kuchulukitsa kwa zochitika za hepatic transaminases,
Supombocytopenia
Pseudomembranous colitis,
Glossitis.

Njira yayitali yothandizidwa ndi Ampicillin imatha kupangitsa kuti odwala asafooke. Zikatero, ndikofunikira kuti mutenge mavitamini.

Migwirizano ndi magwiritsidwe akusungidwa

Ampicillin iyenera kusungidwa m'malo amdima ndi owuma osafikirika ndi ana, kutentha kwa firiji. Alumali moyo wa makapisozi ndi ufa ndi zaka 3, komanso mapiritsi - 2 zaka.

Opanga mankhwala pano amapereka mitundu yambiri ya mankhwala a bacteriostatic. Ena mwa iwo ali ndi zochita zambiri, ena amangomenya ndi tizilombo tating'onoting'ono. Mankhwala oterowo amaletsedwa kumwa okha, chifukwa zotsatira za mankhwala zimatha kukhala zosiyana kwambiri. Nkhani ya lero ikuuzani za Ampicillin. Malangizo ogwiritsira ntchito, kuwunikira, analogi ndi njira yolondola yogwiritsidwira ntchito idzaperekedwa kuti mudziwe.

Nthawi yomweyo onetsetsani kuti zomwe mwalandirazi siziyenera kukulimbikitsani kuti muzisinkhasinkha. Ngati muli ndi mavuto azaumoyo ndipo mukusowa mankhwala oopsa ngati maantibayotiki, muyenera kufunsa chithandizo chamankhwala. Pokhapokha pamenepa pali mwayi wochira mwachangu.

Kufotokozera mwachidule Ampicillin

Chofunikira chachikulu ndi ampicillin. Ichi ndi mankhwala othana ndi chitetezo, omwe amapezeka mu mawonekedwe a mapiritsi, makapisozi, kuyimitsidwa.

Chidachi chimalepheretsa mapangidwe a makoma a bakiteriya. Komanso, Ampicillin imagwira ntchito pokhapokha polimbana ndi tizilombo tating'onoting'ono ta gulu la cocci: staphylococci, gonococci, pneumococci. Komanso mankhwalawa amathandizira Escherichia coli, Salmonella, amalimbana ndi mabakiteriya ena opanda gramu.

Koma nthawi yomweyo, ndizopanda ntchito ndi mitundu ya tizilombo tating'onoting'ono, tomwe timawonongeka pansi pa zochita zawo.

Pakupita maola awiri pambuyo pa utsogoleri, kuchuluka kwa kogwira ntchito mthupi kumafika. Nthawi yochotsa ndi pafupifupi maola awiri - mankhwalawa amuchotsa mkodzo.

Mankhwalawa amadziwika kuti ndi oopsa chifukwa sadziunjikira m'thupi. Chifukwa chake, amaloledwa kuitenga pamtunda waukulu kwa milungu ingapo bwinobwino kuti ikhale ndiumoyo, malinga ndi zomwe zikuwonetsa.

Zisonyezero zogwiritsidwa ntchito:

bronchitis, tonsillitis, sinusitis, otitis media,
urethritis, pyelonephritis, chinzonono,
cholecystitis
gastroenteritis, salmonellosis,
rheumatism, malungo ofiira, sepsis.

Mankhwalawa atha kutumizidwa ndi dokotala yemwe akuwonetsetsa kuti ali ndi mulingo wotani, chithandizo chamankhwala, poganizira zaka za wodwalayo komanso mbiri yakale yakuchipatala. Ndikosatheka kusiya njira yochotsera yochizira kuti matenda asachulukitse matenda.

Kufotokozera mwachidule za Amoxicillin

Amoxicillin ndi mankhwala oteteza khungu ku matenda omwe amalembera mankhwalawa chifukwa cha mabakiteriya omwe amalimbana nawo.

Amoxicillin amagwiritsidwa ntchito chifukwa cha bronchitis, chibayo, komanso matenda opatsirana a pakhungu.

Zizindikiro zazikulu zogwiritsidwa ntchito:

bronchitis, chibayo,
matenda opatsirana a pakhungu
cystitis, pyelonephritis,
matenda a m'matumbo.

Nthawi zina, Amoxicillin amatchulidwa ngati prophylactic panthawi zosiyanasiyana zamankhwala pakamwa zamkati, kuthetsa kwa Helicobacter Pylori. Kuonjezera mphamvu ya mankhwalawa, clavulanic acid ikhoza kutumikiridwa nthawi yomweyo ngati mumwa mankhwalawo.

Amapezeka m'mitundu ingapo: mapiritsi, makapisozi, kuyimitsidwa, yankho la kulowetsedwa kwamkati.

Zotsatira za mankhwalawa zimagwira mabakiteriya okha - Amoxicillin sichikhudza bowa, ma virus. Osagwiritsa ntchito maantibayotiki chifukwa cha chimfine, izi zingapangitse kukulira kwa kukana kwa ma virus.

Kodi pali kusiyana kotani?

Kusiyana kofunikira ndi chinthu chogwira ntchito. Chifukwa chake, pakupanga Ampicillin pali sodium ampicillin, mu mawonekedwe ake - amoxicillin trihydrate. Mankhwala amasiyananso mosiyanasiyana. Kwa ampicillin, nseru, kutsegula m'mimba, dysbiosis, ndi kukula kwa candidiasis ndizodziwika bwino.

Amoxicillin amathanso kukhala ndi dyspeptic reaction, kukula kwa superinitness, komwe kumachitika chifukwa cha kuchuluka kwa tizilombo tina.

Zomwe zili bwino Ampicillin ndi Amoxicillin

Nenani kuti ndibwino - simungathe. Ndi dokotala yekhayo amene angakupatseni mankhwala othandizira, malinga ndi madandaulo a wodwala, zotsatira za mayeso ake. Koma nthawi zambiri pakuchiza matenda opatsirana a bakiteriya omwe amachitika kwambiri, tikulimbikitsidwa kutenga Amoxicillin, wothandizidwa ndi clavulanic acid kuti tithandizire.

Ampicillin amagwiritsidwa ntchito makamaka pochiza matenda opatsirana.

Pa nthawi yoyembekezera komanso mkaka wa m'mawere, mutha kumwa mankhwalawa pokhapokha mukaonana ndi dokotala ngati phindu kwa mayi limaposa zovuta zomwe zingachitike kwa mwana wosabadwayo kapena mwana. Ndipo ana kuyambira ali aang'ono amatha kupatsidwa Amoxicillin, kupatsidwa kulemera ndi msinkhu wa wodwalayo.

Kodi ndingamwe Amoxicillin m'malo mwa Ampicillin?

Malinga ndi mankhwala, 2 mwa othandizira awa ali ndi zofanana. Pazifukwa izi, akatswiri ambiri amapereka Ampicillin kapena Amoxicillin. Komabe, sizingatheke kusankha mankhwala ndikuchita nokha - ndi dokotala yekha amene angachite izi.

Komabe, ngati chithandizo chikufunika kugwiritsa ntchito mapiritsi kwa nthawi yayitali, Ampicillin amatchulidwa chifukwa cha kuchepa kwa thupi. Ngati mumwa Amoxicillin pafupipafupi, izi zimatha kuyambitsa mavuto.

Ngati mungalowe m'malo Amoxicillin ndi mankhwala achiwiri, ndiye kuti chifukwa cha kuchepa kwa thupi, kuchuluka kwa mankhwalawo m'magazi sikungakhale kokwanira. Pankhaniyi, matendawa atha kudwala kwambiri, ndiye kuti chithandizo kuchipatala chikufunika.

Maganizo a madokotala ndi kuwunika kwa odwala

Olga, wazaka 42, wochita zamatsenga

Zochizira za ENT pathologies ndi matenda am'matumbo, Amoxicillin amaperekedwa kwa odwala. Chipangizochi sichotsika mtengo, chimalimbana ndi tizilombo tambiri, tili ndi bioavailability wambiri, zomwe zimatithandizira kuchepetsa kutalika kwa mankhwalawa komanso kuwonjezereka kwa mphamvu ya mankhwalawa. Nthawi zambiri, palibe zoyipa zimachitika.

Irina, wazaka 35, Moscow

Chifukwa cha kudwala kwambiri, adayamba chibayo, ndipo matendawa adatenga mawonekedwe osakhazikika. Dokotala adalemba Amoxicillin monga gawo la zovuta mankhwala. Pambuyo masiku 7, adayamba kumva kupepuka, chifuwa ndi malungo ake zidatha. Pambuyo pa chithandizo, adokotala adalangiza kumwa mankhwala osokoneza bongo.

Elena, wazaka 24, Perm

Ndinkadya zipatso zosasamba bwino, chifukwa cha poyizoni chifukwa cha matumbo. Anachitira ndi Ampicillin 5 masiku. Munthawi imeneyi, zinali zotheka kuchotsa zizindikilozo. Ndinamwa maantibayotiki bwino, kunalibe zotsatirapo zake.

Kuzindikira koyambirira: mawonekedwe omasulidwa, mtengo wake ndi kapangidwe kake

Mphamvu yogwira ya mankhwala ndi pawiri yotchedwa ampicillin trihydrate. Ma Analogs a antibayotiki awa amathanso kukhala ndi mawonekedwe omwewo kapena amasiyana magawo ake. Muphunzira za iwo mtsogolomo m'nkhaniyi. Ampicillin amapezeka kwambiri monga mapiritsi ndi ufa. Chotsirizachi chimakonzekera makonzedwe amkati kapena mtsempha. Njira yothetsera vutoli iyenera kukhala yokonzekera. Momwe mungachite bwino - amafotokozera malangizo mwatsatanetsatane. Pocheperapo pakugulitsa mutha kupeza kuyimitsidwa.

Mtengo wa mankhwalawo ndiwotsika mtengo. Ampicillin adakhalapo pamsika wamankhwala kwa nthawi yayitali. Mutha kugula popanda mankhwala. Mapiritsi okhala ndi kuchuluka kwa zidutswa 20 za ma milligram 250 adzakuwonongerani ma ruble 20. Kutengera ndi wopanga, mtengo wake ungasunthire pang'ono kapena pansi. Mutha kugula botolo ndi ufa jakisoni wa ma ruble 15. Zomwe zili ampicillin mumtsuko wotere zingasiyane: 200, 250, 500 ndi 1000 milligrams.

Kodi Ampicillin amagwira ntchito bwanji?

Mankhwala "Ampicillin" amatanthauza antibacterial semisynthetic mankhwala a penicillin. Chidachi chimakhala ndi zochita zambiri, chifukwa chake, chimatumizidwa kwa odwala popanda kumera koyamba kuti mumveke. Mankhwalawa amalepheretsa kuphatikizika kwa khungu la bakiteriya, lomwe limakhala ndi bactericidal.

Mankhwala omwe amagwira ntchito amagwira ntchito motsutsana ndi tizilombo tambiri ta aerobic, tokhala ndi gramu komanso gram alibe.Mankhwalawa ali ndi opanda. Simatha kuletsa kuchulukitsa kwa mabakiteriya omwe amapanga penicillinase. Tsoka ilo, alipo ambiri pano. Nthawi zambiri michere yamagetsi imeneyi imapangidwa chifukwa chogwiritsa ntchito molakwika maantibayotiki. Izi zimatsimikiziranso kuti simungathe kudzilimbitsa, koma muyenera kulumikizana ndi madokotala kuti akuthandizeni.

Penicillin

Kodi ndingasankhe ndekha za Ampicillin ndekha? Madokotala onse komanso anthu omwe ali ndi maphunziro azachipatala amayankha funsoli mogwirizana: ayi. Chowonadi ndi chakuti ena osinthana ndi mawonekedwe owoneka bwino; akhoza kukhala osathandiza pamachitidwe ena. Ngati pazifukwa zina simungagwiritse ntchito Ampicillin, mbadwo watsopano wa analogues kapena cholowa m'malo mwake uyenera kuvomerezedwa ndi dokotala.

Mukudziwa kale kuti mankhwalawo ndi a gulu la penicillin. Chifukwa chake, mankhwala ena osankhidwa nthawi zambiri amasankhidwa kwa iwo. Ngati tikulankhula za mankhwala omwe mankhwala omwe ali ndi ampicillin trihydrate, ndiye kuti mankhwala otsatirawa amatha kusiyanitsidwa: Zetsil, Stanzacillin, Penodil, Purcillin, Pentrexil, ndi zina zambiri. Kumbukirani kuti mankhwalawa "Ampicillin" akhoza kupangidwa ndi opanga osiyanasiyana. Chifukwa chake, dzina la malonda ake likusinthidwanso: "Ampicillin trihydrate", "Ampicillin sodium salt", "Ampecillin Innotek".

Mutha kusintha chida ndi ma penicillin mankhwala ndi zinthu zina zogwira ntchito. Pankhaniyi, zithunzi za Ampicillin zidzakhala ndi gawo ili:

amoxicillin (Augmentin, Ecobol, Flemoxin),
phenoxymethylpenicillin ("Clacil", "Ospen"),
oxacillin ("Prostaflin"),
piperacillin (Pizellin, Pipraks) ndi ena.

Njira ina: Maantibayotiki otchuka

Analogues a Ampicillin amatha kukhala ndi zinthu zina zogwira ntchito. Izi ndi mankhwala okhudzana ndi ena. Nthawi zambiri amasankhidwa monga choloweza mmalo mukakumana ndi ziwopsezo za wodwala. Mankhwala ena amagwirizana ndi m'badwo watsopano wa maantibayotiki. Chifukwa chake, chida "Ampicillin" analogues chili ndi izi.

Cephalosporins: Cefatoxime, Ceftriaxone, Suprax.
Macrolides: Sumamed, Vilprafen, Klacid.
Tetracyclines: Minolexin, Unidox, Tigacil.
Aminoglycosides: "Gentamicin", "Neomycin", "Streptomycin".
Lincosamides: Nerolen, Dalacin, ndi ena ambiri.

Zizindikiro zogwiritsidwa ntchito komanso zoletsa kugwiritsa ntchito Ampicillin

Mtheradi analogi wa Ampicillin, monga penicillin antibayotiki pawokha, nthawi zambiri amapatsidwa mankhwala opatsirana kudzera kupuma: bronchitis, chibayo. Mankhwalawa amagwiritsidwa ntchito mu ENT pochita matenda a mphuno, pakhosi ndi khutu. Amalembera bakiteriya matenda am'mimba, genitourinary system. Zizindikiro zogwiritsidwa ntchito ndi meningitis, sepsis, matenda a pakhungu, rheumatism.

Musanagwiritse ntchito mankhwala a "Ampicillin" a antiotic, ndikofunikira kuwerengera malangizo. Samalani kwambiri contraindication ndi zovuta zimachitikira. Chifukwa chake, mwachitsanzo, mankhwalawa "Ampicillin" ndiosavomerezeka kugwiritsa ntchito mwachidwi kwambiri pazinthu zake, chifuwa kwa ena. Kugonjera kudzapatsanso matenda a mononucleosis, chiwindi ndi magazi. Mankhwalawa ndi osathandiza motsutsana ndi ma virus a virus.

Ampicillin: malangizo ogwiritsira ntchito

Mitu ya mankhwalawa nthawi zonse imakhala ndi njira yosiyanasiyana yogwiritsira ntchito. Yang'anirani izi. Kugwiritsa ntchito molakwika mankhwala opha maantibayotiki kumabweretsa zotsatira zosayembekezereka: kuyambira pakukanika kwa mankhwala mpaka imfa. Mukudziwa kale kuti Ampicillin akupezeka m'mitundu iwiri: mapiritsi ndi jakisoni (mutha kupeza kuyimitsidwa, koma sikotchuka kwambiri). Momwe mungagwiritsire ntchito moyenera?

Mapiritsi amatchulidwa muyezo 1 mpaka 2 magalamu a yogwira patsiku (wogawidwa mu 4 waukulu). Kwa ana, mankhwalawa amayikidwa mogwirizana ndi kulemera kwa thupi. Sikulimbikitsidwa kugwiritsa ntchito mapiritsi pochiza ana.
Mwanjira ya jakisoni, mankhwalawa amalembera achikulire pa 250-500 mg aliyense maola 4 kapena 6 (kutengera matenda ndi kuuma kwa vutolo). Zochizira ana, "Ampicillin" amagwiritsidwa ntchito pazigawo 25 mpaka 50 mg ya mankhwala pa kilogalamu ya kulemera kwa thupi. Ndikofunika kusamala ndi malamulo aseptic mukamapereka jakisoni.

Kutalika kwa chithandizo kumatsimikiziridwa payekhapayekha, koma sikuyenera kukhala kosakwana masiku asanu. Mlingo wapamwamba wa tsiku lililonse kwa munthu wamkulu ndi magalamu 4 a piritsi ndi 14 mu mawonekedwe a jakisoni.

Chithandizo pa mimba ndi mkaka wa m`mawere

Zofanizira zina za Ampicillin zimaloledwa kugwiritsidwa ntchito panthawi yomwe ali ndi pakati, koma malinga ndi zomwe akuwonetsa. Nthawi zambiri, awa ndi mankhwala a penicillin. Amayi amtsogolo amatha kupatsidwa macrolides, koma izi ndizochepa. Mankhwala "Ampicillin" angagwiritsidwe ntchito pa nthawi yomwe mayi ali ndi pakati malinga ndi dokotala. M'pofunika kupewa kumwa mankhwala okhawo oyamba ndi ma trimester oyamba. Kwa amayi oyembekezera, mankhwalawa amawayikidwa mu Mlingo wa munthu malinga ndi dongosolo linalake.

Zatsimikiziridwa kuti chinthu chogwira - ampicillin trihydrate - chimatha kulowa mkaka wa m'mawere. Chifukwa chake, pali mwayi kuti mankhwalawa alowa m'thupi la mwana. Ngati pakufunika chithandizo pakamachitika mkaka wa m'mawere, muyenera kuganizira za kuthetseratu kuyamwitsa.

Zowonjezera zamankhwala

Ngati mumagwiritsa ntchito ma ampicillin analogue pamapiritsi limodzi ndi antibayotiki woyambirira, mphamvu ya mankhwalawa imatha kukula kwambiri. Chifukwa chake, ndikofunikira kusankha chithandizo choyenera. Osaphatikiza Ampicillin ndi maantigenerti am'badwo watsopano ndi othandizira ena omwe ali ndi bactericidal.

Popeza mankhwalawa amachepetsa matumbo am'mimba, izi zingayambitse kuphwanya kwa ntchito. Ma diuretics, ma sorbyt ndi ma laxatives amachepetsa kuyamwa kwa maantibayotiki. Ascorbic acid, mosiyana, amawonjezera. Chonde dziwani kuti mankhwalawa amachepetsa mphamvu zakulera pakamwa.

Zotsatira zoyipa zamankhwala

Mankhwalawa sakukhudzana ndi mankhwala obwera mwatsopano. Sizipitilira kuyeretsa kwapamwamba. Chifukwa chake, mankhwalawa angayambitse zolakwika zingapo. Pakati pawo, pafupipafupi:

kudzimbidwa, mseru, kusanza,
matumbo dysbiosis, kutsekula m'mimba kapena kudzimbidwa,
zotupa zamkamwa, maliseche, khungu,
thupi lawo siligwirizana mu mawonekedwe a edema, urticaria, mantha.

Chiwopsezo kupita ku Ampicillin

Mndandanda wa "Ampicillin" (mu ma jakisoni kapena mapiritsi - zilibe kanthu) kuchokera ku gulu la penicillin, monga mankhwala pawokha, nthawi zambiri kumayambitsa mkangano. Komabe, imatha kukhala ndi mawonekedwe osiyanasiyana. Ngati mudachitapo zotere, muyenera kukumbukira. M'tsogolomu, popereka mankhwala a antibacterial, onetsetsani kuti mwawauza dokotala izi.

Zomwe zimayipa kwambiri ku Ampicillin ndizotupa pakhungu. Zilonda zazing'ono zimatha kupezeka thupi lonse kapena m'malo osiyanasiyana. Chidacho chimayambitsanso kupweteka komanso kulimbitsa khungu. Chochepa chambiri ndikutupa. Ngati ziwonetsero zimachitika, muyenera kufunsa dokotala posachedwa, musamwe mankhwalawa. Mankhwala ena amaphatikizapo kugwiritsa ntchito ma sorbents ndi ma antihistamines. Ndikofunikanso kusankha analog ya antibayotiki.

Ampicillin ndi mowa

Kodi malangizowo akuti chiyani za mankhwalawa "Ampicillin"? Maupangiri amndandanda wa penicillin, komanso maantibayotiki ofotokozedwawo, sawonetsa kuti kuphatikiza zakumwa zoledzeretsa. Kuphatikiza kotereku kumawonjezera mwayi wazotsatira zoyipa. Kuphatikiza apo, Mowa kuphatikiza ndi Ampicillin zimawononga chiwindi ndi m'mimba. Kuphatikiza kwa mankhwala kungapangitse mphamvu ya mankhwalawo.

Ngakhale izi zili choncho, ogula ena amatha kudumpha magalasi angapo nthawi yamankhwala. Odwala amati palibe chomwe chidawachitikira. M'malo mwake, izi ndi mwayi chabe. Mwinanso zovuta zake zidzadziwonekeranso mtsogolo.

Broad-spectrum penicillin antiotic, kusokonezedwa ndi penicillinase

Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD

Mapiritsi loyera, lathyathyathya-cylindrical mawonekedwe a chamfer ndi notch.

Othandizira: wowuma wa mbatata, magnesium wouma, talc, polyvinylpyrrolidone, wapakati pa 80.
Ma PC 10 - matumba otumphuka (1) - mapaketi a makatoni.
Ma PC 10 - mapaketi opanda ma cell contour (1) - mapaketi a makatoni.

Mphamvu yakuyimitsidwa pakamwa loyera ndi tachikasu chachikasu, ndi fungo linalake, kuyimitsidwa koyera ndi utoto wachikasu.

Omwe amathandizira: polyvinylpyrrolidone, 1-amadzi sodium glutamate, disubstituted sodium phosphate kapena anhydrous disodium phosphate, Trilon B, dextrose, vanillin, zonunkhira za chakudya (rasipiberi), shuga woyengetsa kapena shuga woyengedwa.
60 g (5 g yogwira ntchito) - mabotolo (1) athunthu ndi supuni ya mulingo - mapaketi a makatoni.

Mabotolo 10 ml (1) - mapaketi a makatoni.
Mabotolo 10 ml (10) - mapaketi a makatoni.
Mabotolo 10 ml (50) - makatoni.

Ufa wa yankho la jakisoni yoyera, ya hygroscopic.

Mabotolo okhala ndi voliyumu ya 10 kapena 20 ml (1) - mapaketi a makatoni.
Mabotolo okhala ndi voliyumu ya 10 kapena 20 ml (10) - mapaketi a makatoni.
10 kapena 20 ml mabotolo (50) - makatoni.

Zotsatira za pharmacological

Antibiotic gulu la semisynthetic penicillin wambiri zochita. Imakhala ndi bactericidal zotsatira poletsa kapangidwe ka khoma la bakiteriya.

Yogwira polimbana ndi mabakiteriya a grob-zabwino: Staphylococcus spp. (kupatulapo penicillinase yopanga tizilombo ta), Streptococcus spp. (kuphatikiza Enterococcus spp.), Listeria monocytogene, Bakiteriya wa gram-negative aerobic: Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Shigella spp., Salmonella spp., Bordetella pertussis, ena tizilombo ta Haemophilus fuluwenza.

Amawonongeka ndi penicillinase. Acid kugonjetsedwa.

Pharmacokinetics

Pambuyo pakukonzekera pakamwa, imayamwa bwino kuchokera m'mimba, osawononga m'malo am'mimba. Pambuyo pa makonzedwe a makolo (i / m ndi i / v) amapezeka m'magazi mwakuya kwakukulu.

Imalowetsa bwino mu minyewa ndi madzi amthupi, imapezeka muzoyimira zochizira mu pleural, peritoneal and synovial fluid. Imalowa mkati mwa chotchinga chachikulu. Amalowa bwino kudzera mu chotchinga cha magazi -mwazi, pomwe, ndi kutupa kwa ziwalo za muubongo, kupezeka kwa BBB kumawonjezeka kwambiri.

30% ya ampicillin imapukusidwa mu chiwindi.

T 1/1 - maola 1-1.5. Amachotsedwa makamaka ndi mkodzo, ndipo ndende zozama kwambiri zosasinthika zimapangidwa mumkodzo. Pafupifupi pang'ono ndi bile.

Ndi kubayidwa mobwerezabwereza sikumachitika.

Matenda opatsirana komanso otupa omwe amayambitsidwa ndi tizilombo tating'onoting'ono ta ampicillin, kuphatikizapo:

- matenda amtundu wa kupuma (kuphatikiza bronchitis, chibayo, chotupa cha m'mapapo),

- matenda a ziwalo za ENT (kuphatikiza tonsillitis),

- matenda oyamba ndimatenda am'mimba (kuphatikizapo cholecystitis, cholangitis),

- matenda a kwamkodzo thirakiti (kuphatikizapo pyelitis, pyelonephritis, cystitis),

- matenda am'mimba (kuphatikizapo kunyamula kwa salmonella),

- matenda a pakhungu ndi minofu yofewa,

- sepsis, septic endocarditis,

Kuyanjana kwa mankhwala

Probenecid wogwiritsidwa ntchito munthawi yomweyo ndi Ampicillin-AKOS amachepetsa katulutsidwe ka madzi a ampicillin, chifukwa chomwe chikhazikitso chake m'madzi a m'magazi chikuwonjezeka komanso chiwopsezo cha zotsatira zakupha chikuwonjezeka.

Ndi munthawi yomweyo kugwiritsa ntchito Ampicillin-AKOS ndi mwayi wowonjezereka wa zotupa pakhungu.

Pogwiritsa ntchito nthawi yomweyo Ampicillin-AKOS, mphamvu ya mankhwala okhala ndi pakamwa ya estrogen imatsika.

Pogwiritsa ntchito nthawi yomweyo Ampicillin-AKOS, kugwiritsa ntchito mankhwala aminoglycoside kumakulanso.

Malangizo apadera

Mankhwala ndi Ampicillin, kuyang'anira chiwindi ndi impso nthawi zonse ndikofunikira. Akaphwanyidwa, mankhwalawa azisinthidwa.

Mlingo wamphamvu wa mankhwalawa odwala omwe amalephera kupweteka aimpso amatha kukhala ndi vuto loyipa pakhungu lamanjenje.

Ampicillin analogues

Mwa zofananira za Ampicillin, mankhwala otsatirawa amatha kusiyanitsidwa:

Ampicillin-AKOS,
Mchere wa Ampicillin,
Ampicillin-Ferein,
Puricillin
Zetsil
Chikalinda,
Penodil.

Migwirizano ndi magwiritsidwe akusungidwa

Ampicillin iyenera kusungidwa m'malo amdima ndi owuma osafikirika ndi ana, kutentha kwa firiji. Alumali moyo wa makapisozi ndi ufa ndi zaka 3, komanso mapiritsi - 2 zaka.

Kuzindikira koyambirira: mawonekedwe omasulidwa, mtengo wake ndi kapangidwe kake

Kodi Ampicillin amagwira ntchito bwanji?

Mankhwala omwe amagwira ntchito amagwira ntchito motsutsana ndi tizilombo tambiri ta aerobic, tokhala ndi gramu komanso gram alibe. Mankhwalawa ali ndi opanda. Simatha kuletsa kuchulukitsa kwa mabakiteriya omwe amapanga penicillinase. Tsoka ilo, alipo ambiri pano. Nthawi zambiri michere yamagetsi imeneyi imapangidwa chifukwa chogwiritsa ntchito molakwika maantibayotiki. Izi zimatsimikiziranso kuti simungathe kudzilimbitsa, koma muyenera kulumikizana ndi madokotala kuti akuthandizeni.

Penicillin

Mukudziwa kale kuti mankhwalawo ndi a gulu la penicillin. Chifukwa chake, mankhwala ena osankhidwa nthawi zambiri amasankhidwa kwa iwo.Ngati tikulankhula za mankhwala omwe mankhwala omwe ali ndi ampicillin trihydrate, ndiye kuti mankhwala otsatirawa amatha kusiyanitsidwa: Zetsil, Stanzacillin, Penodil, Purcillin, Pentrexil, ndi zina zambiri. Kumbukirani kuti mankhwalawa "Ampicillin" akhoza kupangidwa ndi opanga osiyanasiyana. Chifukwa chake, dzina la malonda ake likusinthidwanso: "Ampicillin trihydrate", "Ampicillin sodium salt", "Ampecillin Innotek".

Mutha kusintha chida ndi ma penicillin mankhwala ndi zinthu zina zogwira ntchito. Pankhaniyi, zithunzi za Ampicillin zidzakhala ndi gawo ili:

amoxicillin (Augmentin, Ecobol, Flemoxin),
phenoxymethylpenicillin ("Clacil", "Ospen"),
oxacillin ("Prostaflin"),
piperacillin (Pizellin, Pipraks) ndi ena.

Njira ina: Maantibayotiki otchuka

Cephalosporins: Cefatoxime, Ceftriaxone, Suprax.
Macrolides: Sumamed, Vilprafen, Klacid.
Tetracyclines: Minolexin, Unidox, Tigacil.
Aminoglycosides: "Gentamicin", "Neomycin", "Streptomycin".
Lincosamides: Nerolen, Dalacin, ndi ena ambiri.

Zizindikiro zogwiritsidwa ntchito komanso zoletsa kugwiritsa ntchito Ampicillin

Ampicillin: malangizo ogwiritsira ntchito

Mapiritsi amatchulidwa muyezo 1 mpaka 2 magalamu a yogwira patsiku (wogawidwa mu 4 waukulu). Kwa ana, mankhwalawa amayikidwa mogwirizana ndi kulemera kwa thupi. Sikulimbikitsidwa kugwiritsa ntchito mapiritsi pochiza ana.
Mwanjira ya jakisoni, mankhwalawa amalembera achikulire pa 250-500 mg aliyense maola 4 kapena 6 (kutengera matenda ndi kuuma kwa vutolo). Zochizira ana, "Ampicillin" amagwiritsidwa ntchito pazigawo 25 mpaka 50 mg ya mankhwala pa kilogalamu ya kulemera kwa thupi. Ndikofunika kusamala ndi malamulo aseptic mukamapereka jakisoni.

Chithandizo pa mimba ndi mkaka wa m`mawere

Zowonjezera zamankhwala

Zotsatira zoyipa zamankhwala

Mankhwalawa sakukhudzana ndi mankhwala obwera mwatsopano. Sizipitilira kuyeretsa kwapamwamba. Chifukwa chake, mankhwalawa angayambitse zolakwika zingapo. Pakati pawo, pafupipafupi:

kudzimbidwa, mseru, kusanza,
matumbo dysbiosis, kutsekula m'mimba kapena kudzimbidwa,
zotupa zamkamwa, maliseche, khungu,
thupi lawo siligwirizana mu mawonekedwe a edema, urticaria, mantha.

Chiwopsezo kupita ku Ampicillin

Ampicillin ndi mowa

Broad-spectrum penicillin antiotic, kusokonezedwa ndi penicillinase

Zogwira ntchito

Ampicillin (mu mawonekedwe a trihydrate) (ampicillin)

Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD

Mapiritsi loyera, lathyathyathya-cylindrical mawonekedwe a chamfer ndi notch.

Mphamvu yakuyimitsidwa pakamwa loyera ndi tachikasu chachikasu, ndi fungo linalake, kuyimitsidwa koyera ndi utoto wachikasu.

Mabotolo 10 ml (1) - mapaketi a makatoni.
Mabotolo 10 ml (10) - mapaketi a makatoni.
Mabotolo 10 ml (50) - makatoni.

Ufa wa yankho la jakisoni yoyera, ya hygroscopic.

Mabotolo okhala ndi voliyumu ya 10 kapena 20 ml (1) - mapaketi a makatoni.
Mabotolo okhala ndi voliyumu ya 10 kapena 20 ml (10) - mapaketi a makatoni.
10 kapena 20 ml mabotolo (50) - makatoni.

Zotsatira za pharmacological

Antibiotic gulu la semisynthetic penicillin wambiri zochita. Imakhala ndi bactericidal zotsatira poletsa kapangidwe ka khoma la bakiteriya.

Amawonongeka ndi penicillinase. Acid kugonjetsedwa.

Pharmacokinetics

Pambuyo pakukonzekera pakamwa, imayamwa bwino kuchokera m'mimba, osawononga m'malo am'mimba. Pambuyo pa makonzedwe a makolo (i / m ndi i / v) amapezeka m'magazi mwakuya kwakukulu.

30% ya ampicillin imapukusidwa mu chiwindi.

T 1/1 - maola 1-1.5. Amachotsedwa makamaka ndi mkodzo, ndipo ndende zozama kwambiri zosasinthika zimapangidwa mumkodzo. Pafupifupi pang'ono ndi bile.

Ndi kubayidwa mobwerezabwereza sikumachitika.

Matenda opatsirana komanso otupa omwe amayambitsidwa ndi tizilombo tating'onoting'ono ta ampicillin, kuphatikizapo:

- matenda amtundu wa kupuma (kuphatikiza bronchitis, chibayo, chotupa cha m'mapapo),

- matenda a ziwalo za ENT (kuphatikiza tonsillitis),

- matenda oyamba ndimatenda am'mimba (kuphatikizapo cholecystitis, cholangitis),

- matenda a kwamkodzo thirakiti (kuphatikizapo pyelitis, pyelonephritis, cystitis),

- matenda am'mimba (kuphatikizapo kunyamula kwa salmonella),

- matenda a pakhungu ndi minofu yofewa,

- sepsis, septic endocarditis,

Contraindication

- Hypersensitivity maantibayotiki kuchokera ku gulu la penicillin ndi maantiretalactam ena,

- Kuwonongeka kwakukulu kwa chiwindi (chogwiritsa ntchito mwauma).

Khazikitsani payekhapokha potengera maphunziridwe ake, malo omwe matendawa akuwonera komanso chidwi cha pathogen.

Mukamwa, pakamwa kamodzi kwa akuluakulu ndi 250-500 mg, mlingo wa tsiku ndi tsiku ndi 1-3 g.Mwambiri mlingo wa tsiku ndi tsiku ndi 4 g.

Kwa ana The mankhwala mankhwala tsiku lililonse 50-100 mg / kg, ana olemera 20 kg - 12.5-25 mg / kg.

Mlingo wa tsiku ndi tsiku umagawidwa mu 4 waukulu. Kutalika kwa chithandizo kumatengera kuopsa kwa matendawa komanso kutha kwa mankhwalawo.

Mapiritsi amatengedwa pakamwa, ngakhale zakudya.

Kukonzekera kuyimitsidwa, 62 ml ya madzi osungunuka amawonjezeredwa ndi vial ufa. Kuyimitsidwa kwamalizo kumachotsedwa ndi supuni yapadera yomwe ili ndi zilembo ziwiri: m'munsi umafanana ndi 2.5 ml (125 mg), wapamwamba kwambiri - 5 ml (250 mg). Kuyimitsako kuyenera kutsukidwa ndi madzi.

Ndi kholo la makolo (i / m, iv / jet kapena iv drip) limodzi mlingo kwa akuluakulu ndi 250-500 mg, mlingo wa tsiku ndi tsiku ndi 1-3 g, mu matenda oopsa, tsiku ndi tsiku mlingo ungathe kuchuluka mpaka 10 g kapena kuposa.

Makanda obadwa kumene The mankhwala mankhwala tsiku lililonse 100 mg / kg, ana a mibadwo ina - 50 mg / kg. Mu matenda opatsirana kwambiri, mankhwalawa amatha kuwirikiza kawiri.

Mlingo wa tsiku ndi tsiku umagawidwa jakisoni wa 4-6 ndikupangika kwa maola 4-6. Kutalika kwa kachitidwe ka / m ndi masiku 7-14. Kutalika kwa ntchito ya IV ndi masiku 5-7, kutsatiridwa ndi kusintha (ngati kuli kotheka) kumayambiriro kwa IM.

Njira yothetsera makulidwe a mu mnofu imakonzedwa ndikuwonjezera 2 ml ya madzi a jekeseni pazomwe zili mu vial.

Pa jakisoni wa iv, muyeso umodzi wa mankhwalawa (osaposa 2 g) umasungunuka m'madzi a 5-10 ml ya jakisoni kapena yankho la isotonic ndikuwubayira pang'onopang'ono kwa mphindi 3-5 (1-2 g kwa mphindi 10-15). Pa mlingo umodzi wopitirira 2 g, mankhwalawa amaperekedwa. Pazomwezi, muyezo umodzi wa mankhwalawa (2-4 g) umasungunuka mu madzi a 7.5-15 ml ya jakisoni, ndiye kuti yankho lake limawonjezeredwa ndi 125-250 ml ya isotonic sodium chloride solution kapena 5-10% yodzilowetsa komanso jekeseni mwachangu madontho a 60-80 / mphindi Ndi iv drip mu ana, njira ya shuga ya 5-10% (30-50 ml malinga ndi zaka) imagwiritsidwa ntchito ngati zosungunulira.

Malangizo amagwiritsidwa ntchito mukangokonzekera.

Zotsatira zoyipa

Zotsatira zoyipa: zotupa pakhungu, urticaria, edema ya Quincke, pruritus, exfoliative dermatitis, erythema multiforme, kawirikawiri - anaphylactic mantha.

Kuchokera m'mimba: nseru, kusanza, kutsekula m'mimba, glossitis, stomatitis, pseudomembranous colitis, dysbiosis yamatumbo, kuchuluka kwa hepatic transaminases.

Kuchokera ku hemopoietic system: kuchepa magazi, leukopenia, thrombocytopenia, agranulocytosis.

Zotsatira chifukwa chemotherapeutic kanthu: candidiasis mkamwa, candidiasis.

Bongo

Kuyanjana kwa mankhwala

Ndi munthawi yomweyo kugwiritsa ntchito Ampicillin-AKOS ndi mwayi wowonjezereka wa zotupa pakhungu.

Pogwiritsa ntchito nthawi yomweyo Ampicillin-AKOS, mphamvu ya mankhwala okhala ndi pakamwa ya estrogen imatsika.

Pogwiritsa ntchito nthawi yomweyo Ampicillin-AKOS, kugwiritsa ntchito mankhwala aminoglycoside kumakulanso.

Malangizo apadera

Mochenjera ndi poyambira kugwiritsa ntchito nthawi imodzimodziyo mankhwala ogwiritsa ntchito mankhwala, mankhwala ayenera kuperekedwa chifukwa cha mphumu ya bronchial, fever fever ndi zina.

Pakukonzekera kugwiritsa ntchito Ampicillin-AKOS, kuyang'anira mwatsatanetsatane aimpso, chiwindi ndi chithunzi cha magazi ndizofunikira.

Ngati vuto la chiwindi likulephera, mankhwalawa ayenera kugwiritsidwa ntchito motsogozedwa ndi chiwindi.

Odwala omwe ali ndi vuto la impso amafunikira kukonza mankhwalawa malinga ndi QC.

Mukamagwiritsa ntchito mankhwalawa muyezo waukulu mwa odwala omwe amalephera kuwonongeka, aimpso zimatheka.

Mukamagwiritsa ntchito mankhwalawa mankhwalawa sepsis, zimachitika ndi bacteriolysis (Yarish-Herxheimer reaction).

Ngati thupi lanu siligwirizana ntchito Ampicillin-AKOS, mankhwalawa ayenera kusiyidwa ndipo mankhwala osafunikira ayenera kuyikidwa.

Odwala ofooka omwe amatha kugwiritsa ntchito mankhwalawa kwa nthawi yayitali amatha kuyamba kupatsidwa mphamvu chifukwa cha tizilombo tating'onoting'ono tokhala ndi ampicillin.

Popewa kukula kwa candidiasis nthawi imodzi ndi Ampicillin-AKOS, nystatin kapena levorin ayenera kutumikiridwa, komanso mavitamini a gulu B ndi C.

Mimba komanso kuyamwa

Ndikotheka kugwiritsa ntchito mankhwalawa panthawi yomwe muli ndi pakati malinga ndi zomwe zimachitika nthawi yomweyo pamene phindu kwa mayi limaposa chiwopsezo cha mwana wosabadwayo.

Ampicillin amapukusidwa mkaka wa m'mawere mozama. Ngati ndi kotheka, kugwiritsa ntchito mankhwalawa panthawi yoy mkaka wa m'mawere ayenera kuganizira za kuyamwitsa.

Ndi chiwindi ntchito

Kugwiritsa ntchito kwa makolo kumalimbikitsidwa pakhungu la chiwindi.

Migwirizano ndi magwiritsidwe akusungidwa

Mndandanda B. Mankhwalawa amayenera kusungidwa m'malo owuma, amdima, mapiritsi ndi ufa pokonzekera kuyimitsidwa - kutentha kwa 15 ° mpaka 25 ° C, ufa pokonzekera yankho la jekeseni - pa kutentha osaposa 20 ° C. Alumali moyo mapiritsi, ufa kuyimitsidwa ndi ufa yankho la jekeseni ndi zaka 2.

Kuyimitsidwa okonzekeraku kuyenera kusungidwa mufiriji kapena kutentha firiji kwa zosaposa masiku 8. Mayankho okonzekera a i / m ndi utsogoleri wa iv samakhala osungika.

Terms a Tchuthi cha Pharmacy

Mankhwala ndi mankhwala.

Malangizo ogwiritsira ntchito. Contraindication ndi mawonekedwe omasulidwa.

Mankhwala othana ndi penicillin ambiri. Amagwira bactericidal, akuletsa kaphatikizidwe ka khoma la bakiteriya. Yogwira polimbana ndi tizilombo toyambitsa gramu: cocci - Staphylococcus spp. (kupatulapo penicillinase yopanga tizilombo ta), Streptococcus spp. (kuphatikiza Enterococcus), mabakiteriya osapanga spore - Listeria monocytogene. Ampicillin imagwiranso ntchito polimbana ndi tizilombo tating'onoting'ono ta gram-hasi: aerobic - Neisseria gonorrhoeae, Neisseria meningitidis, Escherichia coli, Shigella spp., Salmonella spp. Ampicillin amawonongedwa ndi penicillinase. Acid kugonjetsedwa.

Pambuyo pakukonzekera pakamwa, imatengedwa bwino kwambiri kuchokera m'mimba. Ampicillin imagawidwa mu ziwalo zambiri. Imalowa m'matumbo, kusalowa bwino BB. Ndi kutupa kwa meninges, kuvomerezeka kwa BBB kumawonjezeka kwambiri. 30% ya ampicillin imapukusidwa mu chiwindi. Amachotseredwa mkodzo ndi bile.

Matenda opatsirana komanso otupa omwe amayambitsidwa ndi tizilombo tating'onoting'ono tokhala ndi ampicillin: incl. matenda a khutu, mmero, mphuno, matenda odontogenic, matenda a bronchopulmonary, matenda apakati ndi matenda am'mimba, kuphatikizapo matenda am'mimba, cholecystitis, matenda am'mimba, meningitis, endocarditis, septicemia, sepsis, rheumatism, erysipelas matenda a pakhungu ndi minofu yofewa.

Khazikitsani payekhapokha potengera maphunziridwe ake, malo omwe matendawa akuwonera komanso chidwi cha pathogen.
Mukamamwa pakamwa kwa akulu, muyezo umodzi ndi 250-500 mg, pafupipafupi makonzedwe a 4 / tsiku. Ana omwe ali ndi thupi lolemera mpaka 20 makilogalamu amapatsidwa 12,5-25 mg / kg maola 6 aliwonse.
Kwa makina a intramuscular, intravenous, muyezo umodzi wa akulu ndi 250-500 mg maola 6 kapena 6. Kwa ana, mlingo umodzi ndi 25-50 mg / kg.
Kutalika kwa chithandizo kumatengera malo omwe matendawa ali ndi matendawa komanso mawonekedwe a matendawa.
Mulingo woyenera: kwa akulu, tsiku lililonse pakamwa makonzedwe a 4 g, tsiku lililonse mlingo wa intravenous ndi mu mnofu makonzedwe ndi 14 g.

Zotsatira zoyipa: urticaria, erythema, edi ya Quincke, rhinitis, conjunctivitis, kawirikawiri - malungo, kupweteka kwa molumikizana, eosinophilia, osowa kwambiri - anaphylactic.
Kuchokera mmimba: kukhumudwa, kusanza, dysbiosis yamatumbo, colitis yoyambitsidwa ndi C. bidi.
Zotsatira chifukwa chemotherapeutic kanthu: candidiasis pamlomo wamkati, vagidi candidiasis.

Hypersensitivity kuti ampicillin ndi penicillin ena, chiwindi ntchito.

Mimba komanso kuyamwa

Mwinanso kugwiritsa ntchito ampicillin pa nthawi ya pakati malinga ndi mawonekedwe. Ampicillin amapukusidwa mkaka wa m'mawere mozama. Ngati ndi kotheka, kugwiritsa ntchito ampicillin pa mkaka wa m`mawere ayenera kusankha pa kuyamwitsa.

Munthawi ya chithandizo ndi ampicillin, kuwunika mwatsatanetsatane ntchito za impso, chiwindi ndi chithunzi cha magazi ndizofunikira. Odwala omwe ali ndi vuto laimpso amafunika kukonza njira ya dosing malinga ndi mfundo za QC.
Mukamagwiritsa ntchito Mlingo wambiri kwa odwala omwe amadziona kuti aimpso amalephera, zotsatira zoyipa zamkati mwa mtima zimatheka.
Ampillillin akagwiritsidwa ntchito kwa odwala omwe ali ndi bacteremia (sepsis), zimapangitsa bacteriolysis reaction (the Yarish-Herxheimer reaction).

Probenecid munthawi yomweyo kugwiritsa ntchito ndi ampicillin amachepetsa kubisalira kwa masamba, zomwe zimapangitsa kuchuluka kwa ampicillin m'madzi a m'magazi komanso kuwonjezeka kwa poizoni.
Pogwiritsa ntchito munthawi yomweyo ampicillin okhala ndi mankhwala okhala ndi estrogen, pamakhala kuchepa kwawo, mwina chifukwa chakuchepa kwa kufalikira kwa ma hepatic a estrogens.

Kusunga ndi nyengo ndi malo Osungira malo owuma, amdima, mapiritsi ndi ufa kuti ayimitsitse kukonzekera - kutentha kwa 15 ° mpaka 25 ° C, ufa wowonjezera jakisoni - pamtunda osapitirira 20 ° C.

Moyo wa alumali ndi zaka 2.
Kuyimitsidwa okonzekeraku kuyenera kusungidwa mufiriji kapena kutentha firiji kwa zosaposa masiku 8. Zomwe zakonzedwa kale ku kayendetsedwe ka IM ndi IV sizikusungidwa.