Kuyerekezera kwa Mankhwala Pentoxifylline kapena Trental Ndibwino Chiyani? Zomwe mungasankhe: Pentoxifylline kapena Trental

Zokonzekera zimakhala ndi zomwe zimagwira - pentoxifylline. Katunduyu ali ndi izi:

• kuchitidwa
• chitetezo
• kuchuluka kwamasamba ofiira a m'magazi,
• ntchito mankhwalawa nyamakazi, arthrosis, varicose mitsempha ndi zina matenda,
• mkulu bioavailability
• kulolerana kwachete.

Pentoxifylline kapena Trental ndizofananira wina ndi mnzake.

Mankhwala amagwiritsidwa ntchito pochiritsa kwakanthawi. Amakhala ndi chogwira ntchito kwambiri pochiza matenda a mtima komanso a magazi. Kuphatikiza apo, amatha kugwiritsidwa ntchito poletsa kukhazikika kwa kulowerera kwa myocardial mwa kukonza mkhalidwe wa choroid. Trental ndi Pentoxifylline ali ndi zotsutsana zomwezo:

• manja
• yoyamwitsa
• kwambiri hypotension,
• kusokonezeka kwa mtima,
• matenda a chiwindi
• zotupa m'makutu,
• atherosulinosis
• magazi.

Mankhwala amathandizira kuti athetse ziwopsezo zam'mimba mu bedi lamitsempha ndikuthandizira njira zamagazi. Poyerekeza ndi mankhwala am'deralo, mitundu ya piritsi ingagwiritsidwe ntchito zotupa. Mankhwala onse awiri amathandizira kuchira konse. Komabe, sayenera kuperekedwa kwa odwala omwe akumana ndi vuto la mtima posachedwapa. Pankhaniyi, ndi matenda am'mitsempha, mankhwala ena amakhazikika.

Pentoxifylline imagwiritsidwa ntchito pochiza mtima wa mtima.

Kodi pali kusiyana kotani pakati pa Pentoxifylline ndi Trental

Mankhwalawa ali ndi zambiri zochizira, koma ali ndi zosiyana zochepa zomwe zimagwirizanitsidwa ndi wopanga ndi mtengo.

Kuphatikiza apo, Pentoxifylline imapezekanso ngati yankho. Trental alibe mtundu wofanana ndi kumasulidwa. Izi zimapangitsa kukhala kosavuta komanso mosamala mlingo womwe adokotala akuwonetsa. Mu magawo ena, mankhwalawa ndi omwewo. Ngakhale atachokapo kwambiri, tikulimbikitsidwa kugwiritsa ntchito mankhwala mogwirizana ndi adokotala.

Phukusi lopangidwa ndi Czech lamapiritsi 20 okhala ndi mulingo wa 400 mg limatengera ma ruble 280. Pentoxifylline yokhala ndi dzina la "SZ" yatulutsa nthawi yayitali chogwira ntchito. Mankhwalawa amapangidwa ndi kampani yaku Russia. Amagulitsidwa pamtengo wa ma ruble 240. mapiritsi 20 okhala ndi mulingo wa 400 mg. Mapiritsi a 100 mg yogwira ntchito amtengo kuchokera 235 ma ruble. ma 60 ma PC. Mankhwala osungunuka a mankhwalawa amapezeka mu 5 ml ampoules. Mtengo wa paketi ya ma ampoules 10 ndi ma ruble 50.

Paketi ya mapiritsi 60 a Trental 400 mg opanga French amawononga ma ruble 1,400. Mtundu waku India wa mankhwalawo amagulitsidwa pamtengo wa 650 rubles. mapiritsi 20.

Trental imagwiritsidwa ntchito poletsa kukhazikika kwa myocardial infarction.

Kusankha pakati pa Trental ndi Pentoxifylline, muyenera kufunsa dokotala yemwe adzasankhe mtundu woyenera wa mitundu ndi njira yabwino. Akatswiri amalimbikitsa kupereka zokonda pazoyambira zamankhwala, chifukwa chitetezo ndi kuyenera kwa ntchito kwake kumatsimikiziridwa ndi ziphaso ndi zotsatira za mayeso azachipatala.

Kusamala makamaka posankha mankhwala kuyenera kuwonetsedwa kwa odwala omwe ali ndi mtima wamitsempha yamagazi komanso matenda a hypoxic.

Ndemanga za madokotala za Pentoxifylline ndi Trental

Svyatoslav Pchelintsev (phlebologist), wazaka 40, Bryansk

Mankhwalawa amagwira ntchito mochizira matenda am'mitsempha mwa odwala omwe ali ndi chiopsezo cha thrombosis ndi pathologies a circulatory.Kuti mukwaniritse bwino kwambiri, kudya kwawo kuyenera kutsagana ndi kugwiritsa ntchito mafuta am'deralo ndi mafuta onunkhira. Odwala amalekerera bwino mankhwala.

Arthur Moiseev (phlebologist), wazaka 37, Vladivostok

Nthawi zambiri ndimalandira odwala omwe amadandaula za kutupa, ma mesh venous ndi zowawa m'matumbo. Zikatero, ndimalimbikitsa kugwiritsa ntchito Trental kapena Pentoxifylline. Mankhwala ali ndi zotsatira zofananira ndipo zimapangitsa kuti athetse mwachangu mawonetsero oyipa a matenda amitsempha.

Ngakhale ndalama zitha kutetezedwa, ndikofunikira kukaonana ndi dokotala ndipo mukayezetsa mayeso angapo motsutsana musanawatenge. Izi kupewa mavuto.

Nikolay Brovkin (phlebologist), wazaka 42, Smolensk

Ndikupereka pentoxifylline chifukwa chophwanya ma microcirculation njira ndi venous kusowa nthawi zambiri kuposa Trental. Chithandizo cha mankhwalawa chimatenga nthawi yayitali, choncho ndibwino kuti musankhe chotsika mtengo.

Ndemanga za Odwala

Sergey Lavrentiev, wazaka 49, Balashikha

Pamene ndimachiza matenda a thrombophlebitis, adotolo adamuuza Trental. Gwiritsani ntchito mankhwalawa Mlingo woyenera. M'masiku 2 oyambilira ndimakhala ndi mseru pang'ono, koma nthawi yonseyi chithandizo sichinayambenso. Mankhwalawa ndi othandizadi, mothandizidwa nawo ndinatha kuchira kwathunthu. Nditamaliza maphunziro a mankhwalawa, ndinayamba kumva bwino.

Nika Sablina, wazaka 53, Voronezh

Kwa pafupifupi zaka 5, akhala akuvutika ndi mitsempha ya varicose. Poyamba, matenda a zamatsenga sanadzipangitse okha. Komabe, pakapita nthawi, mitsempha ya kangaude, kulemera kwamiyendo ndi kutupa kunayamba. Pang'onopang'ono kusokonezekaku kunakulirakulira. Zotsatira zake, ndidaganiza zopita kwa phlebologist wodziwika bwino kuti andisankhire njira zabwino komanso zabwino kwa ine. Dokotala adalemba Pentoxifylline. Ndinagula ku pharmacy. Ndinayamba kugwiritsa ntchito mankhwalawa pafupipafupi kwa milungu 4. Panthawiyi, sanaphonyepo muyezo komanso kuwona Mlingo womwe katswiri adawonetsa. Maphunzirowa atatha, mawonekedwe osasangalatsa anasowa.

Mikhail Smagin wazaka 50, Sergiev Posad

Kuchita ndi varicose mafuta. Mwezi ndi theka zapitazo, adotolo adalangiza kugwiritsa ntchito mapiritsi a Trental. Zotsatira zake, ndinatenga kuvomereza kwathunthu. Munthawi imeneyi, ndasiya zonse zoipa za matenda am'mimba, kupweteka komanso kutupa. Mankhwala abwino. Posachedwa, ndidamlangiza kwa mchimwene wanga, yemwe adakumana ndi vuto lofananalo.

Kutulutsa Mafomu

Chofunikira chachikulu pa mankhwalawa ndi pentoxifylline. Mankhwalawa amapezeka m'mitundu iwiri:

• madzi amkati ndi makonzedwe amkati,
• piritsi

Njira yothetsera jakisoni mu ma ampoules (5 ml) imakhala ndi 100 mg ya pentoxifylline. M'makhosi a mankhwala, Pentoxifylline ampoules amagulitsidwa m'matumba a ma ampoules 10. Liquid for intravenous management amapangidwa mumtsuko wa 100, 250 kapena 500 ml, womwe umakhala ndi 0,08, 0,2 ndi 0,4 g yogwira ntchito.

Mapiritsi okhala ndi mphamvu yoyera kapena yapinki, aliyense ali ndi 100, 200 kapena 400 mg ya pentoxifylline. Phukusi la makatoni limakhala ndi matuza a 1-2 a mapiritsi 10 kapena chikho cha galasi chomwe chili ndi mapiritsi 60 kuti muchite bwino.

Mankhwala

Pentoxifylline angioprotector amasintha kuyenda kwa magazi pochepetsa kuchulukitsa kwa magazi kumaundana ndimitsempha yamagazi. Mwa kuchuluka kwamitsempha yamagazi kumathandizira njira zama metabolic m'makoma amitsempha yamagazi, kubwezeretsanso kwachilendo. Kuchita kwa mankhwalawa kumafikira m'mitsempha, mitsempha ndi ma capillaries, omwe amathandizira kukulitsa mawonekedwe awo, kusintha mawonekedwe a oksijeni pakati pa ziwalo, komanso kupewa kusokonekera m'malo omwe akukhudzidwa. Popeza kuti amapezeka m'magazi, mankhwalawo amachepetsa mitsempha ya magazi ndi kulimbitsa makhoma.

Zizindikiro zogwiritsidwa ntchito

The mankhwala zotchulidwa mankhwala a matenda omwe amachepetsa magazi ndi mitsempha yamagazi.

Kukhazikitsidwa kogwira ntchito kwa Pentoxifylline kumaganiziridwa chifukwa cha ma pathologies:

• kusintha kwamitsempha yamagazi ndi rheumatism, osteochondrosis, matenda a msana,
• matenda ashuga
• atherosulinosis ndi zizindikiro zake (kupweteka pamutu, mavuto a kukumbukira, kusowa tulo),
• zotumphukira zamagazi zamagetsi komanso kusowa kwa venous,
• Kuchepetsa mphamvu ya m'mitsempha yamagazi,
• matenda a mtima
• post-stroke, post-infarction and post-apoplectic therapy,
• Matenda a Raynaud
• matenda a ma cell zakudya zama minofu ndi ziwalo (varicose mitsempha, gangrene, frostbite wa malekezero, trophic mwendo zilonda zam'mimba,
• matenda okhudzana ndi zovuta zamagazi mu ubongo,
• discirculatory encephalopathy,
• kuperewera kwa virology etiology,
• matenda amitsempha ya diso,
• Kusintha koyipa kwa ziwiya za khutu lapakatikati ndikukumva kwapang'onopang'ono kwa khutu.
• Mphumu ya bronchial,
• Matenda oletsa kupweteka m'mapapo,
• kusabala kwa mtima.

Gwiritsani ntchito pa nthawi yoyembekezera

Popeza mankhwalawa sanayesedwe pa amayi oyembekezera, madokotala samapereka mankhwala a Pentoxifylline pa nthawi yapakati. Malangizo omwewo amagwiranso ntchito pa nthawi yoyamwitsa, popeza mankhwalawa amalowera mkaka wa mayi. Popereka mankhwala kwa amayi oyamwitsa, tikulimbikitsidwa kuti musamayamwitsa pakadali pano kapena m'malo mwake ndi analogue yoopsa yakhanda kwa mwana.

Mlingo ndi nthawi ya chithandizo

Kutalika kwa mankhwala ndi mlingo zimadalira kuuma kwa matenda. Mapiritsi kapena jakisoni - adokotala amasankha potengera momwe wodwalayo alili. Mapiritsi a Pentoxifylline nthawi zambiri amatchulidwa ngati chithandizo chothandizira kupweteka kwa msana ndi molumikizana, ndi radiculitis, osteochondrosis mu siteji yovuta, ma intraarterial droppers a yankho kapena jekeseni wamitsempha amalembedwa.

Amodzi mwa mankhwalawa amaphatikizidwa ndi 250 ml ya saline, pambuyo pake amayamba kupanga pang'onopang'ono. Nthawi zambiri kudulira kumatenga pafupifupi maola awiri. Ngati ndi kotheka, adotolo amawonjezera ndende ya Pentoxifylline.

Zochizira ndi osteochondrosis, jekeseni 2-3 patsiku ndi mankhwala, nthawi ya chithandizo imayambira milungu iwiri mpaka mwezi.

Radiculitis mankhwala amatenga pafupifupi miyezi iwiri ndi mtsempha wa magazi a 100-200 mg wa yogwira mankhwala kapena kudzera m`mitsempha. Chifukwa chaichi, kuchuluka kwa mankhwalawa kumaphatikizidwa ndi 50 ml ya saline ndikulowetsedwa mu mtsempha kwa mphindi 15.

Osteochondrosis mu pachimake gawo amathandizidwa ndi intra-ochepa ogwetsa, zomwe zimathandizira kukwaniritsa zabwino zabwino.

Fomu ya piritsi imalembedwa pamlingo wokhululukidwa komanso pakalibe zizindikiro zapadera. Mankhwalawa amatengedwa katatu patsiku, piritsi limodzi. Mlingo womwe umafunika (100 kapena 200 mg) - akuwonetsa dokotala. Ndi radiculitis, mlingo waukulu wa 400 mg katatu patsiku tikulimbikitsidwa. Kutalika kwa chithandizo ndikochepera mwezi, zizindikiritso zoyambirira zimapezeka pambuyo masiku 14 akuvomerezedwa. Pankhani ya matendawo kwambiri, othandizira amapereka chithandizo cha Pentoxifylline pakamwa komanso mwamphamvu.

Kodi Trental ndi chiyani?

Trental ndi vasodilator. Amapangidwa kuchokera ku Xanthine. Chida ichi chimagwiritsidwa ntchito pochiza matenda omwe amayambitsidwa ndi zovuta zamagazi m'matumbo.

Kuchita bwino kwa chida kumatsimikiziridwa ndi kukhoza kwake kuwonjezera magazi at kuchepa kwakukulu m'maso ake.

Trental amachita maselo ofiira a m'magazianagonjetsedwa kwambiri kuwonongeka pa matenda enaake, ndi mapulatele kulimbikitsa njira yophatikiza.

Chidacho chimalimbikitsa Sinthani ma microcirculation m'malo a thupi komwe magazi amayenda.

Trental imathandizira kuchepetsa zizindikiritso zomwe zimawonedwa ndimatenda owenderera.

Werengani zambiri zamomwe mungabwezeretsere ndikusintha kayendedwe ka magazi m'thupi lathu.

Zotsatira za pharmacological

Chipangizocho chili ndi mphamvu zambiri zamankhwala:

• imathandizira kukulitsa khoma lamitsempha, popanda kusintha kwambiri kugunda kwa mtima,
• Amayenda ndi magazi,
• bwino kagayidwe kachakudya njira mu chapakati mantha dongosolo,
• bwino kagayidwe kachakudya kagayidwe kachakudya,
- imathandizira kukweza,
• Amachepetsa magazi,
• imalimbikitsa bwino erythrocyte elasticity,
• imathandizira kutuluka kwa mpweya kupita ku myocardium,
• Amachepetsa kutumphukira kwamitsempha,
- imamasula minofu yosalala yotupa,
• otsika kupatsidwa zinthu za m'magazi,
- imalimbikitsa kusungunuka kwabwino kwambiri kwa magazi m'zotengera,
• imakhudza kuthamanga kwa magazi popanda kusintha kugunda kwa mtima,
• amadziunjikira asidi wa adenine m'makoma a mtima,
- amalimbikitsa kupuma bwino ma cell a impso, dongosolo lamanjenje lamanja ndi miyendo,
• Imachepetsa kuchititsa phosphodiesterase, kukulira kwamphamvu mtima,
• imakhala ndi analgesic zotsatira,
• imakulitsa kuunikira kwa ziwiya zam'mapapo,
• Amasintha mamvekedwe a minofu yopuma,
• Amathandizira ntchito zam'madzi mkati mwa ubongo,
• imalimbikitsa kayendedwe ka magazi kupita ku ziwalo zotumphukira miyendo.

Zofunika! Mankhwala akaphatikizidwa pokhudzana ndi kulumikizana mosakhalitsa. Mukamalandira ndalama zogulira usiku, wodwalayo amachepetsa ng'ombe. Kuchiza ndi mankhwalawa kumakulitsa mtunda woyenda wodwalayo.

Chofunikira chachikulu cha mankhwalawa ndi pentoxifylline. Zolemba zake piritsi limodzi ndi 100 mg. Pentoxifylline imapezeka m'malo ambiri a Trental. Kuti muchepetse njira yogwiritsira ntchito mankhwalawa, zotsatirazi zimawonjezeredwa monga zokopa:

• talc,
• silicon dioxide,
• magnesium yakutha,
• wowuma,
• lactose.

Mapiritsi ali ndi:

• sodium hydroxide,
• talc,
• macrogol,
• titanium dioxide,
• Copolymer wa methaconic acid.

Mapiritsi osokoneza bongo opangidwa ndi 400 mgkuwonjezera apo povidone ndi hyetellose.

Kutulutsa Fomu

Chipangizochi chimapezeka m'njira ziwiri zazikulu:

• mapiritsi 100 ndi 400 mg
• yang'anani, pamaziko a njira yothetsera jakisoni 5 ml.

Zomwe zimapangidwira zimaphatikizira pentoxifylline kuchuluka 20 mlkomanso sodium chloride ndi madzi a jakisoni.

Kodi mankhwalawa amwedwa bwanji?

Chida chimagwiritsidwa ntchito pochiza matenda:

• myocardial infaration,
• matenda a mtima,
• matenda a ubongo
• kudalirana kwina,
• mphumu,
• otosulinosis,
• encephalopathy,
• zilonda zam'mimba,
• Ischemic stroke,
• wolanda,
• Matenda a Raynaud,
• chisanu,
• mitsempha ya varicose,
• zogonana chifukwa chosayenda bwino,
• zovuta kuzungulira kwa diso retina.

Kuyerekeza kwa Trental ndi Pentoxifylline

Pentoxifylline ndiye mndandanda waukulu wa Trental. Mankhwala onse awiriwa ali ndi chinthu chimodzi chogwira ntchito, pentoxifylline. Mankhwala amagawana zofanana pofotokoza mwatsatanetsatane, koma pali zosiyana zingapo.

Trental ndi dzina lamalonda Pentoxifylline. Ubwino waukulu wa mankhwala oyamba ndi:

• Kuchita bwino komanso chitetezo,
• zotsatira zabwino zama cell ofiira m'magazi potukula ma pulasitiki,
Kugwiritsidwa ntchito ngati mankhwala ochizira matenda amitsempha,
• mkulu bioavailability wa mankhwala, mankhwala 93%,
• kuleza mtima kwabwino.

Choyipa chachikulu chazida ndi chake mtengo. Watha 250 ma ruble pa paketi iliyonse ya mapiritsi 100 mg. M'masitolo ena ogulitsa, mtengo umafika 480 ma ruble kunyamula.Mtengo wonyamula Trental mu mawonekedwe a mapiritsi a 400 mg amasiyana mderali 400-550 ma ruble. Ampoules a mankhwalawa ndi otsika mtengo kwambiri Ma ruble 150.

Chidacho chidapangidwa kuti chizigwiritsidwa ntchito kwa nthawi yayitali, zomwe zimawonanso zosankha zake ngati chithandizo chachikulu.

Pentoxifylline kapena Trental chimodzimodzi mankhwalawa zotumphukira magazi matenda. Njira zonse ziwirizi zimalimbikitsidwa pochizira lamisi.

Njira zimathandizanso pochiza mtima wa mtima. Mankhwala amalimbikitsidwa kuti ndiwo njira yoyambira yothanirana ndi matenda a sitiroko.. Onse a Trental ndi Pentoxifylline ndi ofanana analimbikitsa ngati prophylactic mankhwala ndi chiwopsezo chachikulu cha munthu yemwe akupanga kulowetsedwa kwa myocardial.

Mankhwalawa onse ali ndi mndandanda umodzi wa zotsutsana, kuphatikizapo:

• kuthamanga kwa magazi,
• mimba ndi kuyamwitsa,
• kutaya magazi kwambiri,
• arrhythmia,
• coronary arteriosulinosis,
• kukoka kwa khungu m'maso.

Yang'anani! Trental ndi Pentoxifylline sichilandiridwa ndi odwala omwe angokhala ndi myocardial infaration. Mankhwala onse awiriwa amaperekedwa pokhapokha ngati wodwala akuchira.

Kusiyanitsa ndalama kuli motere.

Ndemanga pazabwino za Trental kapena Pentoxifylline zikuwonetsa kukhalapo kwa mavuto omwewo m'mankhwala onse awiri. Pentoxifylline ili ndi mtengo wotsikirapo poyerekeza ndi Trental. Ndikulimbikitsidwa kuti ndizikonda mankhwalawo kutengera mtundu wake ndi wopanga.

Kuyerekeza kwa Trental ndi Wasonite

Flowerpot, ngati Trental, ili ndi zofanana:

• Amachepetsa kuchepa kwa magazi,
• Amakongoletsa kukoka kwam'mimba,
• imathandizira kuti pakhale mpweya wabwino kumankhwala,
• limafinya mitsempha yamagazi.

Chipangizocho chimathandizira pakukulitsa kwamitsempha yama coronary.

Mankhwalawa ali ndi zabwino zingapo poyerekeza ndi zoyambirira. Wasonite amadziwika ndi mkulu bioavailability. Ubwino wake ndi 94%, chomwe ndi chizindikiro chokwanira kwambiri pazofanizira zonse za katundu wokhazikika, wopitilira mtengo wake wa Trental yomwe.

Mankhwala ali ndi theka moyo. Amakhala ndi dongosolo Maola 2-3. Hafu ya moyo wa mankhwala imagwirizanitsidwa ndi mawonekedwe a kumasulidwa kwake.

Flowerpot imapezeka m'mapiritsi. Piritsi limodzi lili 600 mgntchito yogwira.

Mankhwala onse awiriwa ali ndi mndandanda womwe ungachitike pazotsatira zoyipa.

Mtengo wazogulitsa ndiwokwera kuposa mtengo wa Pentoxifylline, koma wotsika kuposa Trental. Mtengo wa kunyamula Wazonite ndi 280-345 rubles.

Poyankha funso, lomwe ndi labwino, Flowerpot kapena Trental, ndikofunikira kutuluka mankhwala zonse zikutanthauza. Ali munjira zambiri ndi ofanana chifukwa cha kukhalapo kwa yogwira chimodzimodzi pentoxifylline pokonzekera zonse ziwiri. Flowerpot ili ndi mtengo wotsikirapo poyerekeza ndi yoyambayo.

Fananizani ndi ma fanizo ena

Zofanizira za Trental ndizophatikizira:

• Agapurin,
• Pentilin,
• Kusinthasintha,
• Latren.

• mankhwalawa rheumatism,
• Ndi mavuto ndi kufalikira kwa magazi khutu lamkati,
• kupewa magazi kuundana,
• kuti magazi azitha kupita kumalire.

Pentilin amagwiritsidwa ntchito kwambiri pa matenda a Raynaud, otosulinosis, matenda a mtima, matenda a shuga, komanso mavuto okhudzana ndi ubongo.

Flexital nthawi zambiri imagwiritsidwa ntchito pa ngozi ya cerebrovascular and atherosulinosis.

Latren ali ndi katundu wofanana ndi mankhwala ena onse.

Kuphatikiza apo, imagwiritsidwa ntchito pochotsa dermatitis. Chidacho chimagwira ntchito bwino limodzi ndi mankhwala ena omwe amagwiritsidwa ntchito pochiza mitsempha ya varicose, gangrene, zilonda zam'mimba, frostbite.

Ndalama izi ndizotsimikizira zotsatirazi:

• Agapurin 90%,
• Pentilin 93%,
• Flexital 92%,
• Latren 91%.

Wocheperako theka-moyo kusangalatsidwa ndi Latrena. Ali theka la ola. Mulingo wapamwamba ndi maola 1.5. Zofananira zina zimawonetsedwa ola limodzi kuposa chida chachikulu.

Mitundu yosiyanasiyana yotulutsira zaperekedwa Agapurina. Mankhwalawa amapezeka pamapiritsi malinga 100, 400, 600 mgkomanso ma ampoules.

Mukulozera kwamtengo njira yabwino kwambiri ya analog ndiy Latren. Mankhwalawa amapezeka pokhapokha pobayira jekeseni malinga 100, 200, 400 ml. Mtengo wa ma ampoules ndi 130 ma ruble. Ndalama zomwe zatsala zili pagululi 82-320 rubles kutengera mtundu wa kumasulidwa kwawo.

Werengani nkhani zathu pazomwe zimapangitsa kuti magazi azikula, komanso kuchuluka kwa magazi m'magazi ndi chiyani.

Pomaliza

Mankhwala onse amadziwika ndi mndandanda wazotsatira zoyipa zofanana ndi Trental.

Ndiye chabwino ndi chiani, Trental kapena Pentoxifyline, kapena ma analogu ake ena? Ubwino wa ma analogu onse mumtengo wawo wotsika mtengo. Zoyenera kutengera ndi mtengo, mtundu ndi mawonekedwe a kumasulidwa kwake ndi Pentilin. Ndi chithandizo chankhanza, Pentoxifylline sikhala yofunikira kwenikweni chifukwa cha kuchuluka kwa mankhwalawa. Ngati njira ina, tikulimbikitsidwa kugwiritsa ntchito vasonite mu mlingo wa 600 mg. Chofala kwambiri pakati pa zithunzi zonse ndi kuchuluka kwa Latren.

Makhalidwe a Pentoxifylline

Ichi ndi antispasmodic omwe ali ndi antiaggregational ndi angioprotective zotsatira. Amapezeka m'mapiritsi komanso yankho la kulowetsedwa. Gawo lalikulu ndi pentoxifylline. Mankhwalawa amathandizira kuchepetsa kuthamanga kwa magazi komanso kusiya kupweteka kwambiri pamutu. Mothandizidwa ndi mankhwalawa, kupatsidwa zinthu za m'magazi ndi erythrocyte kumalephereka, kutsanulira kwawo kumawonjezereka, fibrinolysis imayatsidwa, plasma fibrinogen ndende imachepetsedwa, mamasukidwe amwazi amachepetsa.

Kuphatikiza apo, pentoxifylline ili ndi zotsatirazi:

• amalowetsa magazi m'mitsempha,
• imathandizira atherosulinosis yamitsempha yamagazi,
• imasunga mpweya wofunikira mu kayendedwe kazinthu,
• chimalimbikitsa kuphatikizana kwa masheya,
• amachulukitsa kukula kwa makoma amitsempha yamagazi,
• amathandiza ndi kulephera kwa mtima
• bwino mantha a mantha.

Kuphatikiza apo, mankhwalawa amathandizira kamvekedwe ka minofu ya kupuma, minofu yamkati ndi diaphragm. Mankhwala amakhudzanso ntchito ya mitsempha ndi ntchito yachilengedwe, kumawonjezera ndende ya ATP mu ubongo. Pamalo pomwe magazi amayenda, mankhwalawa amayenda bwino.

Zisonyezero zogwiritsidwa ntchito:

• paresthesia
• Matenda a Raynaud
• ngozi yamatenda,
• Kuchepetsa mphamvu ya zotumphukira mitsempha,
• kusamva
• bowa wa msomali
• kuthamanga kwa magazi
• kusokoneza endarteritis,
• chisokonezo pakufalikira kwapanthawiyo,
• encephalopathy
• kulankhulirana
• kuphwanya kuchuluka kwa ziwiya zam'mimba.

Pentoxifylline nthawi zambiri imagwiritsidwa ntchito popanga thupi kuti akwaniritse zotsatira za kupompa.

Mankhwalawa nthawi zambiri amagwiritsidwa ntchito popanga thupi kuti akwaniritse zotsatira za kupompa. Pentoxifylline imayendetsedwa kudzera mkati kapena m'mitsempha yamagazi kapena zotumphukira zamagazi, komanso kupsinjika kwa ischemic.

Contraindations akuphatikiza:

• kumva kwambiri pazogulitsa,
• mimba
• yoyamwitsa
• pachimake hemorrhagic sitiroko,
• matenda am'mimba
• magazi akulu
• pachimake myocardial infaration,
• galactose kapena glucose malabsorption syndrome, sucrose ndi lactase akusowa, lactose ndi fructose tsankho,
• wazaka 18.

Chenjezo mukamamwa mankhwalawa amayenera kuonedwa ndi odwala omwe ali ndi matenda a chiwindi ndi impso, osalephera a mtima, omwe ali ndi zilonda zam'mimba komanso zilonda zam'mimba, atachitidwa opaleshoni yamagazi osakhazikika.

Mukamamwa mankhwalawo, zotsatirapo zake zimakhala zotsatirazi:

• matenda aseptic meningitis, kukokana, chizungulire, mutu,
• kuda nkhawa, kusokoneza tulo, kukwiya,
• kutsitsa magazi, angina pectoris, arrhythmia, tachycardia,
• magazi kwambiri (m'mphuno, m'mimba, kuchokera kumatumbo a pakhungu),
• misomali yoluka, zotupa, ming'oma, redness, kuyabwa,
• hypersalivation, kudzimbidwa, kamwa yowuma, kutsekula m'mimba, kusanza, kuphuka, kupweteka kwa epigastric dera, matumbo a atom, anorexia,
• intrahepatic cholestasis,
• scotoma, kuwonongeka kwa mawonekedwe,
• hypofibrinogenemia, pancytopenia, neutropenia, leukopenia, thrombocytopenia,
• bronchospasm, anaphylactic mantha, angioedema.

Ngati mankhwala osokoneza bongo, zizindikiro zotsatirazi zingachitike: chizungulire, kufooka, kukokana, kusokonezeka kwa chikumbumtima, kukwiya, kugona, kumva kutentha kwamphamvu.

Zochita

Izi ndi vasodilating wothandizira amene amachepetsa mitsempha yamagazi ndikuwongolera ma microcirculation. Amapezeka mu mapiritsi ndi njira yothetsera. Gawo lalikulu ndi pentoxifylline. Mankhwala amalepheretsa phosphodiesterase, amakhudza kwambiri masoka a magazi, amasinthasintha ma cellcirculation ndikuwonjezera ndende ya ATP m'maselo ofiira a m'magazi.

Mankhwalawa amakulitsa kuunikira kwa mitsempha ya coronary, chifukwa chomwe mpweya wakuyenda m'matumbo amtundu ukuwonjezeka, ndikupanga antianginal.

Oxygenation yamagazi imayenda bwino chifukwa cha kufutukuka kwa lumen kwa ziwiya zam'mapapu. Kuphatikiza apo, mothandizidwa ndi mankhwalawa, kamvekedwe ka minofu ya kupuma kumakula. Mankhwalawa, operekedwa kudzera m'mitsempha, amatha kupititsa patsogolo magazi.

Trental imabweretsa kuwonjezereka kwa kutanuka kwa maselo ofiira am'magazi, kupatsirana kwa maselo a m'magazi, ndi kuchepa kwa mamvekedwe amwazi. Chifukwa cha kuwonongeka kwa mitsempha yodutsa komanso kupindika kwapang'onopang'ono, mankhwalawa amachotsa zowawa, kukokana usiku mu ana ang'ono, ndikuthandizira kutalika koyenda.

Trental imathandizira kupweteka, kukokana usiku mu ana a ng'ombe, kumathandizira kutalika kwa mtunda woyenda.

Zisonyezero zogwiritsidwa ntchito:

• zotumphukira ochepa ochepa matenda a matenda ashuga kapena atherosulinotic (mwachitsanzo, matenda ashuga angiopathy, malankhulidwe apakati),
• zovuta zamagazi mu retina,
• pambuyo pa sitiroko ndi mkhalidwe wa ischemic,
• ngozi yamitsempha: kusokonezeka kwa kukumbukira, chizungulire, kusasamala
• zovuta zamatenda, monga gangrene, zilonda zam'miyendo.

Contraindations akuphatikiza:

• magazi akulu
• mimba
• yoyamwitsa
• wazaka 18
• pachimake myocardial infaration,
• matenda am'mimba,
• kukhathamiritsa kwakukulu kwa retinal,
• kumva kwambiri pazigawo za mankhwala.

Chenjezo mukatenga Trental liyenera kuonedwa ndi anthu omwe ali ndi vuto lalikulu la mtima.

Pa chithandizo, zotsatirazi zoyipa zimachitika nthawi zambiri:

• kukokana, aseptic meningitis, chizungulire, mutu,
• kuda nkhawa, kusokoneza tulo, kukwiya,
• m'matumbo, magazi am'mimba, kutsekeka kwa khungu, angina pectoris, kutsika kwa mavuto, arrhythmia, tachycardia,
• Hypersalivation, kudzimbidwa, kutsegula m'mimba, kusanza, kusanza, kumva kupweteka m'mimba, matumbo a m'matumbo, kukomoka, mkamwa wowuma,
• intrahepatic cholestasis,
• hypofibrinogenemia, pancytopenia, thrombocytopenia, neutropenia, leukopenia,
• scotoma, kuwonongeka kwa mawonekedwe,
• kutupa, kuchuluka kwa misomali, urticaria, erythema, zotupa, kuyabwa,
• bronchospasm, anaphylactic mantha, angioedema.

Pakakhala vuto losokoneza bongo, chizindikiritso monga chizungulire, kusanza kwa magazi, mseru, kutsika kwamphamvu kwa magazi, kusokonezeka kwa phokoso la mtima, kusokonezeka kwa chikumbumtima, komanso kupweteka.

Kodi kusiyana ndi kufanana kwa Pentoxifylline ndi Trental ndi kotani?

Mankhwala osokoneza bongo amafanana kwambiri:

• mawonekedwe a mapiritsi (mapiritsi ndi jakisoni)
• kupezeka kwa chinthu chimodzi - pentoxifylline,
• momwemonso momwe amagwirira ntchito pa thupi,
• onse ndi angioprotectors
• magawo a pharmacological: mankhwala amalowetsedwa kwathunthu m'magazi, ndi kuthira mkodzo patsiku,
• zotchulidwa angiopathy ndi thrombosis,
• Zithandizo za mitsempha ya varicose, kuthandiza ndi mitsempha ya varicose,
• kumwa pambuyo chakudya ndi madzi ambiri
• bongo
• mavuto omwewo
• mndandanda wazonse wazopondera
• kuwonjezera mphamvu ya maantibayotiki, ma antiplatelet othandizira ndi antihypertensive mankhwala,
• zoperekedwa ndi mankhwala.

Kusiyana pakati pa mankhwala ndi:

• Dziko lomwe adachokera: Trent ikupezeka ku India, Pentoxifylline - ku Russia ndi Ukraine,
• kuchuluka kwa yogwira piritsi limodzi.

Malingaliro a madotolo

Ekaterina, wazaka 49, phlebologist, ku Moscow: “Anthu omwe ali ndi mitsempha yapamwamba ya varicose nthawi zambiri amabwera kudzalandira. Matendawa amatengera zilonda zam'mimba komanso zilonda zam'mimba. Pankhaniyi, ndikuwapatsa Pentoxifylline. Amathana bwino ndi vutoli, koma amatha kuyambitsa mavuto. "

Igor, wazaka 52, phlebologist, Kazan: "Machitidwe anga, nthawi zambiri ndimapereka mankhwala a Trental kwa odwala anga omwe ali ndi vuto lozungulira la cellcirculatory. Zimathandizira kuchotsa zilonda zam'mimba, zimapangitsa khungu kukhala lofewa komanso kuthetsa kutsekeka. Ndi bwino kuyiyendetsa bwino, chifukwa pamenepa imachitika mofulumira. ”

Contraindication

Mankhwalawa sanalembedwe kwa odwala omwe ali ndi izi:

• tsankho pazigawo za mankhwala (ziwengo),
• mtima pathologies mu pachimake gawo (kugunda kwa mtima, sitiroko, myocardial necrosis),
• ngozi yamatenda,
• magazi
• aimpso ndi chiwindi kulephera,
• kukonzanso pambuyo ntchito
• kuchepetsedwa kupanikizika
• ana ochepera zaka 12
• kuyamwitsa ndi kubereka mwana.

Zotsatira zoyipa

Pentoxifylline ndi mankhwala wololera mosavuta. Zotsatira zoyipa nthawi zambiri zimayambitsidwa ndi zifukwa ziwiri:

• bongo
• kuphwanya malamulo a kulowetsedwa kwa mankhwala kudzera mu mtsempha wa magazi kapena mtsempha wa magazi.

Gawo lomaliza ndilofunikira - kuwonjezereka kwa liwiro la kayendetsedwe ka mankhwala kumabweretsa zotsatirapo zoyipa, chifukwa chake, malangizo a Pentoxifylline amawonetsa nthawi yayitali, kuchepetsa kwake komwe sikungovomerezeka.

Madokotala amalingalira izi kuchokera pazifukwa zomwe zalembedwa:

• kusowa tulo, kupweteka m'mutu ndi khosi, kuchepa kwa mawonekedwe, nkhawa zopanda pake,
• arrhasmia, kuthamanga kwa magazi,
• kudzimbidwa, kusowa kudya, kumva kuwuma komanso kuwawa mkamwa.
• redness khungu, kuyabwa ndi khungu,
• malungo, kukomoka, kusazindikira, stenosis ya larynx.

Mbali Yapadera

Mankhwala ali ndi izi:

1. Kutulutsa mawonekedwe ndi kapangidwe kake. Mankhwala obwera ali ndi mawonekedwe a mapiritsi okhala ndi 100 kapena 400 mg ya mankhwala othandizira komanso magawo ena othandiza. Trental imatha kupangidwa mwanjira yokhazikika, kuchokera komwe yankho la jakisoni limakonzedwa. 1 ml ya mankhwalawa imakhala ndi 200 mg ya pentoxifylline ndi 800 mg ya madzi a jakisoni.
2. Zotsatira za pharmacological. Mankhwalawa amachepetsa kuyanjana kwa magazi, kumawonjezera kuchuluka kwa maselo ofiira am'magazi, komanso kupewa kuphatikizana kwa maplatelet. Kugwiritsa ntchito mankhwalawa kumathandizira kukulitsa ziwiya zazing'ono ndikubwezeretsa microcirculation. Minofu imayamba kulandira mpweya wokwanira, zomwe zimapangitsa kuti ululu komanso kukokana zizichoka.
3. Zizindikiro zogwiritsidwa ntchito. Mankhwalawa amagwiritsidwa ntchito kupewetsa ndikuchotsa kufalikira kwa venous. Nthawi zambiri amamuikira varicose mitsempha ndi matenda ena a mtima, kupangitsa kuti magazi asokonekera.
4. Njira yogwiritsira ntchito. Mapiritsi amatengedwa pakamwa katatu patsiku. Zomwe zili pamapulogalamuwa zimaphatikizidwa ndi 250-500 ml ya mchere. Mankhwalawa amaperekedwa pang'onopang'ono, kawiri kawiri pa tsiku.
5. Zotsatira zoyipa. Ndi kuyambitsa kwa yankho, chizungulire, malingaliro osokoneza, kusowa tulo, kuwulutsa kutentha kumaso ndi chifuwa, kupweteka kwamtima kumatha kuchitika. Zotsatira zoyipa za mapiritsi pamatumbo am'mimba zimafotokozedwa kuchepa kwa chilimbikitso, ziwalo zamkamwa zowuma, komanso kuwonjezeka kwa ntchito ya michere ya chiwindi. Kukhazikitsidwa kwa Mlingo wambiri kungayambitse magazi. Ndi kusalolera kwa zigawo zikuluzikulu za mankhwalawa, matupi awo sagwirizana amachitika mu uritisaria, anaphylactic mantha ndi edincke's edema.
6. Contraindication Trental sinafotokozeredwe magazi othamanga, myocardial infarction, hemorrhagic stroke, mtima mungoli chisokonezo, hypersensitivity kuti pentoxifylline. Mndandanda wa contraindication umaphatikizapo pakati ndi kuyamwa. Mosamala, jakisoni ndi mapiritsi amagwiritsidwa ntchito pochotsa impso ndi chiwindi.

Zabwino ndi zoyipa zazinthu zoyambirira

Odwala nthawi zambiri amafunsa: ndizabwino - Trental kapena pentoxifylline. Pankhaniyi, ndikofunikira kukumbukira kuti Trental ndilo dzina lamalonda la pentoxifylline. Izi ndi mankhwala apachiyambi, omwe adayambitsidwa pamsika wamankhwala ndi Sanofi-Aventis. Mtsogolomo, makampani ena adayamba kupanga mankhwalawo pansi pa mayina osiyanasiyana ogulitsa. Mankhwala ofanana ndi a majenito.

Mwa zabwino zamankhwala odziwika, mfundo zotsatirazi zitha kusiyanitsidwa:

1. Mankhwalawa adapangidwa koyambirira kwa 70s ku Germany ndipo lero ndi amodzi othandiza kwambiri komanso otetezeka.
2. Kugwiritsa ntchito mankhwalawa kumapangitsa kuti mapuloteni azikhala ndi magazi ofiira.
3. Chipangizochi chimagwiritsidwa ntchito kwambiri pochita opaleshoni ndipo kuyambira 2004 amadziwika kuti ndi imodzi mwazonse zamankhwala otupa.
4. Mankhwalawa amatengeka ndi zoposa 90%.
5. Zotsatira zamaphunziro ambiri azachipatala zimatsimikiziranso kulekerera bwino komanso njira zoyenera zochizira.

Mankhwala amathandizira popereka zotsatira za angioprotective, amatulutsa magazi m'mitsempha yaying'ono ndipo amathandizira pakukula kwawo. Mankhwalawa ali ndi zochizira komanso prophylactic, kugwiritsa ntchito kwake kumakupatsani mwayi woletsa kupitilira kwa matenda enaake.

Kukhazikitsidwa kwa mankhwalawa pamsika wamankhwala kwasintha kwambiri malingaliro a madokotala pakuwongolera kwamankhwala osokoneza bongo. FDA yavomereza kugwiritsa ntchito mankhwalawa pochiza ma cell angapo a mtima.

Mwa zoperewera, mtengo wokwera kwambiri wa mankhwala a Trental amatha kusiyanitsidwa poyerekeza ndi analogues. Mankhwalawa amapangidwira kuti azigwiritsidwa ntchito kwa nthawi yayitali, chifukwa chake izi zimatha kukhala zochepa kwa odwala angapo.

Pentoxifylline kanthu

Mankhwala ali ndi izi:

• sinthidwa kusintha kwa magazi ndikusintha magazi m'thupi,
• amachepetsa ntchito ya phosphodiesterase, imathandizira kuti pakhale cyclic adenosine monophosphate mu maselo a minyewa yosalala ya minyewa yamagazi ndi zinthu zamagazi,
• amalepheretsa kulumikizana kwa maselo ofiira am'magazi ndi mapulateleti, amathandizira kuchuluka kwa maselo amwazi,
• amachepetsa kuchuluka kwa fibrinogen mu madzi am'magazi, kumathandizira kuchepa kwa fibrin, kumachepetsa mawonekedwe am magazi ndikuwonjezera kuthamanga kwa magazi m'mitsempha,
• imakulitsa kuwunikira kwamitsempha yamagazi (pentoxifylline samangochepetsa kukana kwamitsempha yamagazi, komanso imabwezeretsa kuzungulira kwa ziwalo za mthupi)
• kubwezeretsa kuperekanso kwa oksijeni ndi michere ku minyewa yaubongo, impso ndi m'munsi mwake.

Kodi pali kusiyana kotani komanso kufanana pakati pa Trental ndi Pentoxifylline?

Makhalidwe ofanana a Trental ndi Pentoxifylline ndi awa:

• mtundu wa kumasulidwa (onsewa ali ndi mitundu ya piritsi ndi jakisoni),
• kukhalapo kwa mankhwala omwewo (pentoxifylline),
• gulu la pharmacological (onse mankhwala ali m'gulu la angioprotectors),
• zomwe zimachitika mthupi la munthu.
• magawo a pharmacokinetic (onse a Trental ndi Pentoxifylline amalowetsedwa kwathunthu m'magazi ndikuwikamo mkodzo patatha maola 24),
• Zisonyezero zogwiritsira ntchito (onsewa ndi mankhwala omwe amaperekedwa ndi mitsempha ya varicose, thrombosis ndi angiopathy),
• dongosolo la dosing (mapiritsi a Trental ndi Pentoxifylline amatengedwa mukatha kudya ndi madzi ambiri)
• mndandanda wazonse wazopondera
• kulephera kugwiritsa ntchito pochizira amayi apakati kapena oyembekezera, komanso ana osakwana zaka 18,
• Zotsatira zoyipa (mankhwalawa onse amatha kuyambitsa matenda osokoneza bongo, kusokoneza ma cell am'magazi ndi kugaya chakudya),
• Zotsatira za bongo,
• mogwirizana ndi mankhwala (onse a Trental ndi Pentoxifylline amalimbikitsa mphamvu ya antihypertensive mankhwala, antiplatelet othandizira ndi maantibayotiki),
• kusiya kupita.

Kusiyana pakati pa mankhwalawa ndi:

• kudziko lomwe adachokera (Trental amapangidwa ku India, Pentoxifylline amapangidwa ndi makampani opanga mankhwala ku Russia ndi ku Ukraine),
• kuchuluka kwa yogwira piritsi 1 (Trental imatha kukhala ndi 100 kapena 400 mg yogwira ntchito, Pentoxifylline imapezeka mu gawo limodzi - 100 mg).

Ndibwino - Pentoxifylline kapena Trental?

Khalidwe la Pentoxifylline lopangidwa ndi Russia silisiyana ndi kugwira ntchito kwa Trental. Mnzake waku Ukraine akhoza kukhala wopanda tanthauzo.

Trental sakonda kuyambitsa zovuta zilizonse, chifukwa madokotala nthawi zambiri amakonda izi.

Njira yothetsera jakisoni imadutsanso magawo ambiri owongolera.

Mtengo wa Pentoxifylline

Mtengo wa Pentoxifylline pamapiritsi ndi ma ampoules zimatengera wopanga. Nthawi zambiri wodwala amasankha pakati pa nkhawa za mankhwala aku Russia, Belarusi ndi Czech. Mankhwala okwera mtengo kwambiri amawonedwa kuti amapangidwa ku Czech, otsika mtengo - Belarusi.

• Pentoxifylline, mapiritsi, 100 mg, zidutswa 60 pa paketi - kuchokera 85 ma ruble (Russia)
• Pentoxifylline, mapiritsi, 100 mg, 60 phukusi lililonse - kuchokera ma ruble 285 (Czech Republic)
• Pentoxifylline, mapiritsi, 400 mg, zidutswa 20 - kuchokera ma ruble 255 (Russia)
• Pentoxifylline, mapiritsi, 400 mg, zidutswa 20 - kuchokera ma ruble 350 (Czech Republic)
• Pentoxifylline, ma ampoules 2%, 5 ml, zidutswa 10 - kuchokera 17 ma ruble (Belarus)
• Pentoxifylline, ma ampoules 2%, 5 ml, zidutswa 10 - kuchokera ma ruble 38 (Russia)

M'malo a Pentoxifylline

Zofanana ndi angioprotective zodziwika ndi zotengera za Pentoxifylline:

• Xanthinol chikonga.
• Mgwirizano.
• Maluwa.
• Agapurin.
• Kusinthasintha.
• Trental.

Trental kapena Pentoxifylline - pali kusiyana kotani?

Mankhwalawa onse ndi angioprotectors omwe amasintha magazi. Pansi pali pentoxifylline, yomwe imalepheretsa mapangidwe a maselo, kupendekeka kwamitsempha, ndikuyenda bwino kwa magazi. ndipo Pentoxifylline imapezeka mu mapiritsi ndi njira zovomerezeka; mawonekedwe ampikisano amafanana.

Kusiyanako kumakhala mumtengo ndi wopanga: Trental imapangidwa ku Europe kapena India, yokhala ndi chiyeretso chachikulu ndi kuwongolera. Nthawi yomweyo, mtengo umakhala wokwera kuposa momwe analogue yaku Russia - Pentoxifylline. Malinga ndi zotsatira za mayeso, analog yachilendo mu mawonekedwe a jakisoni amawonetsa zotsatira zake mwachangu, zitsanzo zaku Russiazo zamaphunziro zotere sizinathe.

Fomu yamapiritsi imasiyana m'mitengo yokha - ku Trental imakhala yokwanira 2 kutalika. Chifukwa chake, poganiza za wodwala, dokotala amalimbikitsa mapiritsi a Pentoxifylline ndi mayankho a Trental.

Pentoxifylline kapena Wasonite - pali kusiyana kotani?

Wazonite ndi chitukuko cha ku Austria chokhazikitsidwa ndi pentoxifylline. Mosiyana ndi pentoxifylline, amapezeka mu mawonekedwe a piritsi okha ndi Mlingo wa 600 mg. Pakati pa mapiritsi onse okhala ndi chinthu chogwira ntchito, Wazonite amawonetsa kuyamwa kwambiri m'mimba. Koma kuchuluka kwa pentoxifylline piritsi kumafunikira magawo ake azithandizo, zomwe ndizovuta kwa odwala.

Agapurin kapena Pentoxifylline - zoti musankhe?

Monga Pentoxifylline, Agapurin amapezeka mu mawonekedwe a mapiritsi ndi madzi a jakisoni. Zolemba za mankhwala ndizofanana, momwe zimagwiritsidwira ntchito komanso mavuto ake. Odwala amakonda kusankha Agapurin, chifukwa mosiyana ndi mnzake waku Russia, mtundu wake umakhala wokwera ndi kusiyana pang'ono pamtengo.

Flexital ndi Pentoxifylline - zotsika mtengo?

Flexital ndi Indian generic Pentoxifylline yothandizanso chimodzimodzi. Poyerekeza ndi yotsirizira, mankhwalawa amamasulira ma vasospasms pamlingo wokulirapo kuposa kukulitsa lumen. Nthawi yomweyo, imakhudza magazi omwe amapezeka kwa ziwalo zina mokakamizidwa hypoxia. Amapangidwa piritsi.

Ngati tizingolankhula za Flexital ndi Trental - zopangidwa ku Indian pharmacology - Flexital ndi yotsika mtengo pamene tikukhalabe apamwamba. Komabe, mankhwalawo sagulitsidwa m'matcheni onse a mankhwala.

Mankhwala "Pentoxifylline" ndi gawo limodzi mwa gulu la hemorheological othandizira, ndi angioprotector. Chifukwa cha malo angapo, zimapangitsa magazi kulowa m'matipi, kuthetsa zizindikiritso ndi zotsatira za hypoxia m'malo ovuta. Chidacho chinalowa machitidwe azachipatala kumapeto kwa zaka 70s zomalizira pansi pa dzina loyambirira la malonda "Trental". Popita nthawi, maupangiri osiyanasiyana a Pentoxifylline adawonekera, zomwe zidapangitsa kuwonjezeka kwa njira zamankhwala. Ngakhale kupezeka kwa mapiritsi komanso kukhalapo kwa iwo mwa zomwezi, zomwe zikuyenera kuchitika, dokotala amayenera kutenga nawo mbali posankha wogwirizira.

Zatsopano zamakono zaku Russia komanso zakumwa zakunja

Kusintha kwa Pentoxifylline ndi maulumikizidwe ake ndi ma jini, madokotala amawongoleredwa osati ndi mtundu wa mankhwala, mtengo ndi mbiri ya wopanga. Kusankha komaliza kumadalira magawo a mankhwala, kuzindikira, komanso kuopsa kwa mkhalidwe wa wodwalayo. Pachifukwa ichi, simuyenera kuyesa kusintha njira yokhazikikayo ngati siyabwino pazifukwa zina.

Trental ndi dzina lamalonda lomwe pentoxifylline limapezeka pamsika wamankhwala. Ngakhale zili zofanana, pali zosiyana zingapo. Trental imapezeka mu mawonekedwe a mapiritsi ndipo mumangofunika kwambiri pakukonzekera kulowetsedwa.

Mankhwalawa amalembera encephalopathies a osiyanasiyana etiologies, ischemic stroke, mavuto a mtima. "Trental" imagwiritsidwa ntchito molimbika kuposa ma fanizo ena mu otolaryngology. A Inde mankhwala amathandiza mavuto a magazi mu vertebrobasillar dongosolo, zomverera kumva, zosiyanasiyana kukhumudwa motsutsana maziko a kuchepa magwiridwe antchito am'mbali.

• magwiridwe antchito ndi chitetezo, zotsatira zabwino pa boma la maselo ofiira amwazi chifukwa chobwezeretsanso mphamvu zawo,
• bioavailability wa mankhwala oposa 93%,
• kulolerana kwabwino, zotsatira zoyipa zochepa kuposa Pentoxifylline,
• hafu ya moyo ndi maola 1-2, omwe ndi mphindi 30-90 poyerekeza ndi omwe anali oyamba.

Choyipa chachikulu cha mankhwalawo ndi mtengo wake. Kwa Trental m'mapiritsi, mafakisoni amafunsira ma ruble 500. Mtengo wamitundu yina yamalonda ungafike mpaka ma ruble 1800. Mankhwalawa amayenera kumwedwa kwa nthawi yayitali kuti mankhwalawa akhale othandizira, chifukwa, mankhwalawa amatha kukhala okwera mtengo kwambiri.

Osati kofala kwambiri, koma kakhalidwe kabwino komanso kogwira mtima ka mankhwala a Pentoxifylline. Imapezeka mu mawonekedwe a mapiritsi, dragees, makapisozi, yankho ndikukhazikika pamakonzedwe ake. Madzi mawonekedwe a mankhwalawa amapangidwira intravenous kapena intraarterial. Mitundu yamitundu yosiyanasiyana ngati imeneyi imalola kugwiritsa ntchito mankhwala aliwonse. Matenda a wodwalayo sangathe kukhala cholepheretsa kuchira.

"Flexital" imathandiza kwambiri pochiza ngozi za cerebrovascular, atherosulinosis ndi mtima. Amagwiritsidwa ntchito pamafungo owopsa a mitsempha ya varicose ndi mwayi wabwino wokulira mphamvu zabwino. Bioavailability wa mankhwalawa akuyandikira 92%. Hafu yake ya moyo ndi maola 1-1,5.

Mankhwalawa amaimiridwa ndi mapiritsi a nthawi yayitali. Kudya kwake kumachepetsa magazi. imakhazikitsa ma microcirculation m'malo ovuta, limasinthasintha njira yoperekera minofu ndi mpweya. Mosiyana ndi analogues, cholowa m'malo mwa mankhwala a Pentoxifylline sichikukula kokha ayi, komanso mitsempha ya coronary.

Ubwino wake ndi kukwera kwake kwachilengedwe - pafupifupi 94%, yomwe imapereka njira yowonjezereka yogwira ntchito. Poterepa, theka la moyo wawo limapangidwira mpaka maola atatu. Mankhwalawa amapezeka kokha mwa mapiritsi, omwe amachepetsa mawonekedwe owagwiritsa ntchito. Mtengo ndi wotsika pang'ono poyerekeza ndi wa Trental, ndichifukwa chake nthawi zambiri malonda amalisinthidwa ndi analogues.

Mankhwala omwe ali ndi mitundu yambiri yogwiritsidwa ntchito pazofanizira zonse zomwe zaperekedwa. Kuphatikiza pazinthu zonse zomwe zidatchulidwa kale, zimagwiritsidwanso ntchito pochotsa dermatitis. Mankhwalawa amagwira ntchito kwambiri pamatenda a Raynaud, mavuto aliwonse okhala ndi minofu yam'mimba. Ophthalmologists amalembera izi chifukwa chophwanya ma cellcirculation a m'maso, otolaryngologists amagwiritsa ntchito kulimbana ndi mtima wamakutu m'makutu, kumvetsera kwakanthawi. The anentoue pentoxifylline Latren nthawi zambiri imaphatikizidwa ndi zovuta mankhwala othandizira zilonda zam'mimba zotupa, gangren, frostbite, mitsempha ya varicose. Itha kugwiritsidwa ntchito pakuwonongeka kwa minofu motsutsana ndi matenda a shuga, pakubwezeretsa nthawi ya ischemic stroke.

The bioavailability wa mankhwala pafupifupi 91%. Hafu ya moyo wawo ndiyofupikitsa pakati pa oloweza - m'malo angapo sizipitilira theka la ola. Chotsatira chake ndi kupezeka kwa mtundu umodzi wokha wa mankhwala - yankho la jakisoni. Izi nthawi zambiri zimayambitsa kuthekera kochiritsira kunja kwa chipatala. Zomwe zimapangidwira zimapezeka pamtengo wotsika bwino.

Chida chachilendo chomwe kwa zaka zambiri chogwiritsa ntchito chalengeza zaudindo wake komanso kudalirika kwawo. Nthawi zambiri, chidwi ichi cha Pentoxifylline chopanga chimalembedwa kwa odwala omwe ali ndi rheumatism, kusokonezeka kwa microcirculation mkati mwa khutu lapakati, komanso mphumu wa bronchial. Mankhwala amaphatikizidwa popewa magazi, omwe amagwiritsidwa ntchito kuti magazi azithamanga m'malo otsika.

Kukhalapo kwa mitundu yosiyanasiyana ya mankhwala kumanenedwa ngati kuphatikiza, komwe kumakulitsa mwayi wakuchitikira. Mosiyana ndi ma analogues, Anapurin amatha kugwiritsidwa ntchito panthawi yoyembekezera ndi chilolezo cha dokotala komanso moyang'aniridwa naye. Zowonongera izi zimaphatikizira kuchepa kwachilengedwe kwa mankhwalawa - 90%.

Kuyerekeza mtengo

Madokotala samalimbikitsa kuti asankhe ma fanizo a mankhwalawo, kutengera mtengo wawo. Ngati mphindi iyi ikakhala yolimba, ziyenera kukumbukiridwa kuti Pentoxifylline ndiye wotsika mtengo kwambiri.Mtengo wake umachokera ku ruble 30-110. Pamalo achiwiri malinga ndi chizindikiro ndi Latren. Itha kugulidwa kwa ma ruble 80-160, koma mankhwalawo ndiwovuta kupeza m'mafakisi. Chotsatira chimabwera Flexital pamtengo wa 90-210 rubles, komabe, sizivuta kugula. Agapurin yotsika mtengo kwambiri imakhala ndi ma ruble 130 pa jakisoni aliyense komanso kuchokera ku ruble 200 piritsi limodzi. "Maluwa" ndi okwera mtengo kwambiri - ma ruble 380. Odula kwambiri pazifanizo zake - Trental mtengo kuchokera kuma ruble 500 ndi pamwamba.

Iliyonse mwa mawu akuti "Pentoxifylline" ali ndi mawonekedwe ake, ngakhale ali ndi zinthu zomwezo. Zofananira zake zonse zimakhala zothandiza komanso zotetezeka ndi njira yoyenera. Chachikulu ndichakuti musachite nawo nokha chithandizo, koma kuti muchite mogwirizana ndi zomwe dokotala wakupatsani.

Microcirculation bwino, angioprotector, dimethylxanthine zotumphukira. Pentoxifylline imachepetsa kukhuthala kwa magazi, imayambitsa kusagwirizana kwa maselo, kumachulukitsa kuchuluka kwa maselo ofiira a m'magazi (chifukwa cha kusokonezeka kwaposachedwa kwa maselo ofiira am'magazi), kumapangitsa kusintha kwakachulukidwe kazinthu zam'magazi komanso kumapangitsa kuti mpweya uzikhala ndi mpweya. Zimawonjezera kuchuluka kwa cAMP m'mapulateleti ndi ATP mu erythrocyte ndi nthawi imodzi yamagetsi yamagetsi, yomwe imayambitsa vasodilation, kuchepa kwa kugunda kwa mtima, kuwonjezeka kwa stroke stroke ndi mphindi yamagazi popanda kusintha kwakukulu pamtima.

Kukula kwamitsempha yama coronary, kumawonjezera kuperekera kwa oksijeni ku myocardium, kumachepetsa ziwiya zam'mapapu, kumapangitsa kuti mpweya wa magazi ukhale wabwino. Kuchulukitsa kamvekedwe ka minofu ya kupuma (minofu yamimba ndi diaphragm).

Mu / kumayambiriro, pamodzi ndi zomwe tafotokozazi, zimabweretsa kufalikira kogwirizana, kuwonjezeka kwa kuchuluka kwa magazi oyenda kudzera m'chigawo cha mayunitsi.

Kuchulukitsa ndende ya ATP muubongo, zimakhudza bwino ntchito ya biioelectric ya mkuu mantha dongosolo. Amasintha kukhathamiritsa kwa magawo m'magazi opatsikira magazi.

Ndi occlusive zotupa za zotumphukira mitsempha (pang'onopang'ono claudication), kumabweretsa kuchuluka kuyenda, kuchotsedwa kwa usiku kukokana kwa minofu ya ng'ombe ndi kupweteka popuma.

Pambuyo pakukonzekera pakamwa, imatengedwa bwino kwambiri kuchokera m'mimba. Pali kagayidwe kakang'ono panthawi ya "gawo loyamba" kudzera m'chiwindi. Amamangirira ma membrane ofiira a magazi. Amakhala woyamba wa maselo ofiira m'magazi, ndiye m'chiwindi. Ma metabolites ena amagwira ntchito. T 1/2 kuchokera ku plasma ya mankhwala osasinthika ndi maora a 0,4-0.8, ma metabolites - maola 1-1.6 Pambuyo maola 24, mlingo waukulu umaperekedwa mkodzo ngati metabolites, gawo laling'ono (pafupifupi 4%) - kudzera m'matumbo.

Kuwonongeka kwa pentoxifylline kumachepetsedwa mwa okalamba odwala ndi matenda a chiwindi.

Matenda oyenderera (kuphatikiza kupatsirana kwina) komwe kumachitika chifukwa cha zovuta zina zamagetsi zamagetsi. Ischemic cerebrovascular ngozi, ischemic stroke ndi pambuyo-stroko, matenda atherosulinosis (chizungulire, kupweteka kwa mutu, kusokonezeka kwa kukumbukira, kusokonezeka kwa kugona), discepulopal encephalopathy, neuroinawon ya viral (kupewa zovuta zam'mimba). Ischemic matenda a mtima, mkhalidwe pambuyo myocardial infaration. Matenda a shuga Matenda oyamba ozungulira a retina ndi choroid, pachimake ischemic optic neuropathy. Otosulinosis, kusintha kwina kozungulira pa maziko a matenda a ziwalo zamkati ndikuchepa pang'onopang'ono kwa kumva. COPD, mphumu ya bronchial. Kupanda mphamvu kwa mtima.

Lowetsani mu / a (ndege kapena malovu), mu / mu (ndege kapena malovu), mu / m, mkati. Mlingo ndi njira zochizira zimakhazikitsidwa payekhapayekha.

Kuchokera kumbali yamanjenje yapakati: mutu, chizungulire, nkhawa, kusokonezeka kwa tulo, kukokana.

Dermatological zimachitika: Hyperemia pakhungu la nkhope, kuthira magazi pakhungu la nkhope ndi chifuwa chapamwamba, kutupa, kuchuluka kwa misomali.

Kuchokera m'mimba: pakamwa youma, kuchepa kwa chakudya, matumbo atomu, kuchuluka kwa cholecystitis, hepatitis ya cholestatic, kuchuluka kwa hepatic transaminases ndi zamchere phosphatase.

Kuchokera kumbali ya gawo la masomphenyawo: kuwonongeka kwa mawonekedwe, scotoma.

Kuchokera pamtima: tachycardia, arrhythmia, cardialgia, angina patsogolo, kutsitsa magazi.

Kuchokera ku hemopoietic system: thrombocytopenia, leukopenia, pancytopenia.

Kuchokera pakupanga magazi: hypofibrinogenemia, magazi ochokera m'mitsempha ya pakhungu, mucous nembanemba, m'mimba, matumbo.

Zotsatira zoyipa: kuyabwa, kumva kwa khungu, urticaria, angioedema, anaphylactic.

Contraindication

Pachimake m`mnyewa wamtima infarction, porphyria, kwambiri magazi, hemorrhagic sitiroko, retinal kukha magazi, pakati, kuyamwa. Kwa iv oyang'anira (osakakamiza) - arrhythmias, atherosclerosis yayikulu ya ubongo kapena mitsempha ya mitsempha, yosagwirizana ya hypotension.

Hypersensitivity kwa pentoxifylline ndi zina zokhudzana ndi xanthine.

Mimba komanso kuyamwa

Maphunziro okwanira komanso olamulidwa bwino azachipatala pachitetezo cha pentoxifylline pa nthawi yomwe ali ndi pakati sanachitike.

Pentoxifylline ndi ma metabolites ake amuchotseredwa mkaka wa m'mawere. Ngati ndi kotheka, ntchito pa mkaka wa m`mawere ayenera kusiya kuyamwitsa.

Gwiritsani ntchito ana

Gwiritsani ntchito mosamala ana ndi achinyamata osakwana zaka 18 (kuchita bwino ndi chitetezo sizinaphunzire).

Zizindikiro zoyambirira za bongo: kufooka, chizungulire, tachycardia ndi kutsitsa magazi, kukulitsa kugona, kukomoka, kukwiya, kupweteka.

Chithandizo Chizindikiro: Kusunga kapena kubwezeretsa magazi, kukhalabe ndi kupuma.

Pentoxifylline imatha kuyambitsa zochitika za antihypertensive mankhwala.

Poyerekeza ndi kholo la makonzedwe a pentoxifylline mu milingo yayikulu, kuchuluka kwa insulin kwa odwala matenda a shuga ndikotheka.

Kugwiritsa ntchito munthawi yomweyo ndi ketorolac, kuwonjezereka kwa magazi komanso / kapena kuwonjezeka kwa nthawi ya prothrombin ndikotheka, ndi meloxicam, kuwonjezereka kwa magazi, ndi sympatholytics, ganglioblockers ndi vasodilators, mwina kuchepetsa kuthamanga kwa magazi, ndi heparin, fibrinolytic mankhwala, kuchulukitsa mphamvu ya anticoagulant.

Cimetidine amachulukitsa kuchuluka kwa pentoxifylline m'madzi a m'magazi, motere, pogwiritsa ntchito munthawi yomweyo, mwayi wazotsatira zoyipa umatha.

Terms a Tchuthi cha Pharmacy

Mankhwala ndi mankhwala.

Migwirizano ndi magwiritsidwe akusungidwa

Pewani kufikira ana pa kutentha osapitirira 25 ° C. Moyo wa alumali ndi zaka zitatu.

Gwiritsani ntchito ntchito yolakwika ya chiwindi

Pakukanika kwambiri kwa chiwindi, makonzedwe a dongosolo la pentoxifylline amafunikira.

Gwiritsani ntchito ntchito yolakwika yaimpso

Ngati vuto la impso, kuwongolera kwa dongosolo la pentoxifylline kumafunika.

Gwiritsani ntchito odwala okalamba

Mwa anthu achikulire, mawonekedwe a mankhwalawa amachepetsedwa, chifukwa chake, kuchepetsa mankhwala kungafunike.

Gwiritsani ntchito mosamala vuto la kuthamanga kwa magazi (kuthana ndi kuchepa kwa magazi), mtima kulephera, zilonda zam'mimba ndi duodenum (pakulimbitsa pakamwa), atachitidwa maopaleshoni posachedwapa, mwa ana ndi achinyamata osakwana zaka zakubadwa. Zaka 18 (zoyenera ndi chitetezo sizinaphunzire).

Ngati aimpso ntchito kapena matenda a chiwindi ntchito, kuwongolera kwa dongosolo la pentoxifylline kumafunika.

Pa chithandizo, kuthamanga kwa magazi kuyenera kuyang'aniridwa.

Pogwiritsa ntchito munthawi yomweyo mankhwala a antihypertensive, insulin, pakamwa hypoglycemic, kuchepetsa kwa pentoxifylline kungafunike.

Pogwiritsa ntchito munthawi yomweyo ndi ma anticoagulants, magawo othandizira magazi amayang'aniridwa mosamala.

Pentoxifylline Ndi chida chamakono chothandiza kusintha kwa microcirculation, angioprotector ndi dimethylxanthine.

Mlingo komanso njira ya makonzedwe: mapiritsi, jakisoni, dontho

Mukamamwa pakamwa, mapiritsi okhala ndi mulingo wa 100 mg amagwiritsidwa ntchito. Amayamba kumwa, makamaka, ndi 200 mg - mapiritsi 2 katatu patsiku mukatha kudya. Kenako, chithandizo chamankhwala chikakwaniritsidwa, mlingo umachepetsedwa, ndipo piritsi limapitilizidwa kumwa katatu patsiku. Njira ya mankhwala piritsi kukonzekera kumatenga mwezi.

Mu matenda owopsa komanso oopsa a ziwalo zamkati, pentoxifylline ndi mankhwala ampoules. Pali njira ziwiri zoperekera mankhwala: intraarterial and intravenous.

Wothandizirayo amayendetsedwa kudzera m'mitsempha ngati woponya. Mbale umodzi umagwiritsidwa ntchito pa 250 ml ya sodium chloride solution, kapena shuga. Mlingowu umaperekedwa kwa ola limodzi ndi theka mpaka maola awiri, pang'onopang'ono.

Mlingo wa tsiku ndi tsiku utha kuwonjezeredwa ndi kulekerera kwabwino kwa 0-0-0.3 g (malingana ndi zisonyezo).

Intraarterally, amayamba kupereka kwa mlingo wa 0,1 g wa mankhwalawa 50 ml ya sodium mankhwala enaake, ndiye 0-0-0.3 g iliyonse.

Njira yothetsera vutoli imalowetsedwa pang'onopang'ono kuposa mphindi 10. Maphunzirowa amagwiritsa 10 infusions.

Thandizo la bongo

Chithandizo cha bongo chimayamba ndi chapamimba thovu, kuyambitsa kukhazikitsidwa kwa kaboni mkati, kubwezeretsa kupuma pantchito ndi matenda a magazi. Panthawi yamavuto owopsa, pakafunika thandizo la akatswiri, dokotala wa ambulansi amafunika. Pankhaniyi, kuyambitsa adrenaline ndikoyenera. Ndi kusanza, thandizo limaperekedwa mwa njira yanthawi yochepetsera kutulutsa magazi m'matumbo.

Zotsatira zakuchipatala

Chiwerengero chachikulu cha mayeso azachipatala atsimikizira kuti mankhwalawa omwe amagwiritsidwa ntchito ndi pentoxifylline ndi amodzi mwa mankhwala omwe amaphunziridwa bwino kwambiri omwe amachotsa mavuto omwe amabwera chifukwa cha kufalikira kwa zotumphukira. Izi zimapangitsa Trental Pentoxifylline mankhwala osankhidwa pa mankhwala a lameness.

Zina mwa zotsatirazi zamankhwala omwe amadziwika ndi mankhwalawa:

1. Kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumalimbikitsidwa: nthawi zina, osachepera miyezi iwiri ndi iwiri mpaka itatu.
2. Mankhwala sayambitsa achire matenda, okhala ambiri antispasmodic mankhwala.
3. Kugwiritsa ntchito pentoxifylline mu mlingo waukulu kwakanthawi kochepa kukuwonetsa kuwongolera kwa mankhwalawa pochiza matenda amitsempha yamagazi.
4. Kugwiritsa ntchito mankhwalawa kumakupatsani mwayi wokana kumwa mankhwala kuchokera pagulu la antispasmodics: Drotaverin, Spazmolitina, Papaverina.
5. Dokotala ali ndi mwayi wosankha mulingo woyenera wa mankhwalawa kwa wodwala aliyense. Nthawi zina, mpaka 1200 mg wa chinthu patsiku amafunikira.

Pentoxifylline imagwiritsidwa ntchito kwambiri pothandizira matenda a trophic. Zotsatira za kafukufuku wazachipatala zimawonetsa, kugwiritsa ntchito mankhwalawa kumathandizira kwambiri kuchiritsa kwa zilonda zam'mimba. Mu maphunziro amodzi, mankhwala a Trental adagwiritsidwa ntchito pa 400 mg kwa miyezi isanu ndi umodzi:

• Zotsatira zabwino zidakwaniritsidwa m'milandu yoposa 84%.
• Ngakhale atagwiritsidwa ntchito nthawi yayitali, mankhwalawa awonetsa kulolera kwambiri.
• Mankhwala amakhalanso achire zotsatira nthawi yonse ya mankhwala.
• Njira yakuchiritsira zilonda zam'mimba imatha kupitilizidwa mwa kuphatikiza kuphatikizira kuluka kwa nsalu.

Mankhwalawa amathandizidwa kuti azitha kuchiza matenda a angiopathy, nephropathy, retinopathy komanso matenda a trophic omwe amapezeka chifukwa cha matenda osokoneza bongo. Zotsatira zakufufuza zimatsimikizira kuti mankhwalawa amathandizira kuchepetsa hyperglycemia. Mphamvu yofuna kupewetsera zinthu zimapangidwa poletsa kupangika kwa glycation. Kudzikundikira kwa zinthuzi kumathandizira kukulitsa zovuta za matenda ashuga.

Kafukufuku wothandiza pa zamankhwala okhudzana ndi chitetezo cha mankhwalawa panthawi ya bere sichinachitike.

Zizindikiro zogwiritsidwa ntchito ndi mankhwala opangidwa ndi pentoxifylline

Mankhwala a Pentoxifylline ndi trental angagwiritsidwe ntchito ngati zikutsimikiziridwa kuti zikuvomerezedwa, monga momwe akunenera komanso moyang'aniridwa ndi dokotala. Zomwe zikugwiritsidwa ntchito ndi mankhwalawa ndi njira yovuta yochizira matenda ndi zinthu zotsatirazi:

• Pambuyo myocardial infaration.
• Panthawi yoperekera zakudya ku minofu yofewa ndi kupangika kwa zovuta za trophic.
• Zomwe zimayendetsedwa ndi zovuta zamagazi: kuphatikiza polankhula pang'onopang'ono.
• Matenda a Raynaud.
• Matenda a mtima.
• Otosulinosis.
• Pankhani ya matenda amitsempha yamagazi yotsekereza yomwe imayambitsidwa ndi chitukuko cha atherosulinosis.
• Kuphwasika kwa masinthidwe abwinobwino m'munda wamasomphenya.
• Mphumu ya bronchial.
• Emphysema m'mapapo.
• Kuchepetsa kapena kumva kwathunthu kwamakutu chifukwa cha kuwonongeka kwa khutu mkati.

Mitsempha yosakanikirana yamankhwala imakupatsani mwayi wopanga ma workaround omwe mumathandizira mitsempha ndi magazi.

Mankhwalawa amagwiritsidwa ntchito kwambiri pochiza matenda osiyanasiyana amitsempha yamagazi, komanso zovuta zamagazi. Mankhwalawa ndi omwe amapanga maziko oyambira, omwe amagwiritsidwa ntchito kuti athetse mavuto omwe amachitika chifukwa cha stroke, komanso panthawi yopewera kulowerera kwa myocardial.

Zokhudza kugwiritsa ntchito mankhwala osokoneza bongo

Pochita ndi mankhwala Trental ndi mawonekedwe ake, wina ayenera kukumbukira za mawonekedwe ogwiritsira ntchito mankhwalawa.

Mankhwala amalimbikitsidwa kuti amwe limodzi ndi zolimbitsa thupi. Mankhwala osakanikirana omwe amaphatikizidwa ndi clopidogrel panthawi yochizira pang'onopang'ono amaloledwa.

Pankhani yogwiritsidwa ntchito nthawi yomweyo ndi mankhwala othamanga magazi, mankhwala omwe amaphatikizapo insulin, komanso mankhwala a hypoglycemic, kusintha kwa mlingo kungafunike.

Ngati kuphwanya kwachilendo kwa kwamikodzo dongosolo, kusintha kwa mankhwala, kuphatikizapo pentoxifylline, kungafunike.

Pankhani yophatikiza ndi mankhwala ochokera ku gulu la anticoagulants, ndikofunikira kuwunika mwadongosolo zizindikiro za magazi.

Ndi kholo makonzedwe a mankhwala pa kuchuluka kwa odwala matenda a shuga, zotsatira za insulin zitha kuchuluka.

Kuwonetsedwa kwa wodwalayo zizolowezi zoyipa (makamaka kusuta) kungasokoneze mphamvu ya mankhwalawa. Poterepa, pali cholepheretsa kagayidwe kake, ndipo kugwiritsidwa ntchito kwa madzi mu plasma kumachepetsedwa ndi oposa 15%.

M'nthawi yonse ya mankhwala ayenera kuwunika magazi.

Ngati ndi kotheka kugwiritsa ntchito mankhwalawa panthawi yoyamwa, muyenera kuganizira kuyimitsa HB.

M'mayeso onse, mayendedwe opanda mayendedwe opanda ululu, komanso zizindikiro zamagazi zakuyezetsa magazi zidawunikiridwa.

Kuyeserera kwa Chitetezo cha Mankhwala

Trental pentoxifylline, komanso mankhwala analog angayambitse kukulitsa zotsatira zoyipa.Izi zimaphatikizapo kukula kwa zovuta zam'mimba, kugaya kwamitsempha, dongosolo lamanjenje, komanso ziwalo zamawonedwe.

Nthawi zambiri zomwe zimanenedwa pakukula kwa kupweteka m'mutu, kusokonezeka kwa tulo, nkhawa zowonjezereka, kukhumudwa, kuwona kwakhungu, mtima arrhythmias, tachycardia, kupita patsogolo kwa angina pectoris, kutsitsa magazi.

Ndizothekanso kukula kwa zoyipa zam'kati ndi matupi awo mutatenga Pentoxifylline ndi Trental: kuwonetsa nkhope, kuwonjezeka kwa msomali wa msomali, zodandaula za kutentha ndi kutentha kwa nkhope ndi chifuwa, urticaria, kuyabwa.

Mankhwalawa sayenera kumwa ngati awa:

• Nthawi yomweyo wodwala akayamba kuvutika ndi myocardial infarction (kokha panthawi yochira moyang'aniridwa ndi dokotala).
• Ndi kuchepa kwamphamvu kwa kuthamanga kwa magazi.
• Pankhani ya kukula pang'onopang'ono, atherosulinosis yamphamvu yam'mimba.
• Ndikukha magazi kwambiri.
• Panthawi ya retinal kukha magazi.
• Pa nthawi ya gestation ndi mkaka wa m`mawere.
• Ndi arrhythmias, osavomerezeka kuperekera mankhwala kudzera m'mitsempha.

Ngati mankhwala okhala ndi pentoxifylline atagwiritsidwa ntchito popanda mankhwala a dokotala komanso kuvomerezedwa kwa muyeso, chiopsezo chokhala ndi mavuto osafunikira chikuwonjezeka. Ngati mankhwala osokoneza bongo, kuchipatala wodwala angafunike.

Kuyanjana kwa mankhwala

Kugwiritsa ntchito nthawi yomweyo kwa meloxicam ndi ketorolac kumawonjezera kutuluka kwa magazi. Pankhaniyi, kuwonjezereka kwa prothrombin index sikungapeweke. Mukamayanjana ndi mankhwala monga ganglion blockers ndi vasodilators, kuchepa kwa magazi kumatheka. Ngati Pentoxifylline amatengedwa limodzi ndi heparin ndi mankhwala ena a fibrinolytic, ndiye kuti ndizotheka kuwonjezera mphamvu ya anticoagulant.

M'zaka zaposachedwa, madera atsopano apezedwa ndikugwiritsa ntchito Pentoxifylline. Pakadali pano, zabwino za mankhwalawa ndi mankhwalawa pamatenda monga matenda oopsa a hepatitis zatsimikiziridwa.

Malangizo apadera

Moyang'aniridwa ndi dokotala, kumwa mankhwalawo kumasonyezedwa chifukwa chophwanya kwambiri impso ndi chiwindi, mukumwa mankhwala a antihypertensive, hypoglycemic othandizira, insulin. Muzochitika izi, kusintha kwa mankhwalawa kwa mankhwala akuluakulu kumafunika.

Pogwiritsa ntchito mankhwala othandizira awa, kuwunika pafupipafupi kuchuluka kwa kuthamanga kwa magazi ndikofunikira.

Mukamagwiritsa ntchito limodzi ndi anticoagulants, kuyang'anira magawo a mapangidwe a magazi kumafunika.

Kwa achikulire, ndikofunika kugwiritsa ntchito Mlingo waung'ono wa mankhwalawa.
Kusuta, monga lamulo, kumachepetsa mphamvu ya mankhwalawa.

Mukamagwiritsa ntchito njira yothetsera kulowetsedwa kwa misempha, ndikofunikira kuyang'ana kuyenderana ndi mankhwala ena nthawi iliyonse. Wodwala ayenera kutenga dontho m'malo osakwiya, osakwiya msanga.

Mitu ya mankhwalawa

Pentoxifylline analogues ndi:

• Agapurin: piritsi la 100 mg, yankho la jakisoni wa 100 mg mu ampoules a 5 ml.
• Vasonite: mapiritsi a 600 mg okhala ndi mafilimu.
• Trental: mapiritsi a 100 mg ndi 400 mg, mapiritsi 100 mg, 100 mg jakisoni mu 5 ml ampoules.

Kugwiritsa ntchito kwake mu otoneurology ndikosangalatsa. Trental imalembedwa kwa odwala ambiri omwe ali ndi vuto lozungulira mu dongosolo la vertebrobasilar. Mwachitsanzo, mwachitsanzo, chifukwa cha kafukufuku womwe anthu 60 adatenga nawo gawo, zotsatira zabwino za kugwiritsidwa ntchito kwa Trental m'matenda a ziwalo zam'makutu zidawululidwa. Zinatsimikizidwanso kuti kumwa mankhwalawa kumathandiza kuti kumva kwamvekedwe komanso zotupa zina zamkati mwa khutu lothandizira. Chifukwa chakuchita bwino kwake, Trental amadziwika ngati mankhwala amakono a chilengedwe. Amalekerera mosavuta ndi odwala ambiri, okwera mtengo, komanso osavuta kugwiritsa ntchito.

Tengani Agapurin mkati, kuyambira piritsi limodzi katatu patsiku. Ndi dontho la kuthamanga kwa magazi, mlingo umachepetsedwa ndikakola kamodzi pakanthawi 2 pa tsiku. Nthawi zambiri njira ya mankhwala ndi masiku 20.

Mwanjira ya jakisoni, mankhwalawa amaperekedwa kudzera m'mitsempha, mkati mwa magazi, komanso mu mawonekedwe a infusions, mumtsinje kapena dontho.

Kumayambiriro kwa chithandizo ndi Agapurin, ampoule umodzi amagwiritsidwa ntchito, omwe amasakanikirana ndi 50 ml ya yankho la 0.9% sodium chloride. Ndi chithandizo chotenga nthawi yayitali, mlingo umatha kuwonjezeka mpaka 200-300 mg. Mlingo wa Agapurin ndi pafupifupi mphindi 10. Maphunzirowa amatenga otsalira a 10-12 tsiku lililonse, kapena tsiku lililonse.

Mtengo wa mankhwalawa umachokera ku ruble 90 mpaka 137. Wopanga - Zentiva AC, Czech Republic.

Mtundu waukulu wamasulidwe ndi piritsi ya nthawi yayitali, mu chigoba choyera, chopanda chopondera mbali zonse ziwiri. Piritsi limodzi lili ndi 600 mg yogwira ntchito - pentoxifylline.

Vasonite imathandizira kupezeka kwa zimakhala ndi magazi ndi okosijeni m'malo omwe akhudzidwa, monga ubongo, chapakati mantha, miyendo ndi malo ena. Imayesa kuchepetsa ziwiya zamagetsi.

Mankhwala amatchulidwa piritsi 2 kawiri pa tsiku - m'mawa ndi madzulo.
Mapiritsi ayenera kumwedwa mutatha kudya ndi madzi pang'ono.
Amakhala ndi zovuta zomwezi monga Pentoxifylline.
Mtengo wa mankhwalawo ndiwokwera kwambiri - pafupifupi ma ruble 330.
Moyo wa alumali ndi zaka 5.

Mtengo wa Pentoxifylline

Mtengo wa Trental umachokera ku ruble 157 mpaka 319, Agapurin amatenga ndalama kuchokera ku 90 mpaka 137 rubles.

Kodi chitha kusintha chiyani ndi mankhwala "Pentoxifylline"? Analogue ya mankhwalawa adzaperekedwa munkhaniyi. Kuchokera pamenepo muphunzira zomwe mankhwalawa amapangidwira, momwe amagulitsira, momwe angagwiritsidwire ntchito, ndi zina zambiri.

Kuphatikizika, mawonekedwe, ma CD

Kodi mankhwala Pentoxifylline amagulitsidwa mwamtundu wanji? Malangizo ogwiritsira ntchito (ma fanizo a mankhwalawa amatha kupezeka mu mankhwala aliwonse) amawonetsa kuti mankhwalawa amapezeka m'njira zosiyanasiyana, monga:

• Mapiritsi (400 ndi 100 mg), omwe amaphatikizidwa ndi zokutira zapinki. Makatoni amodzi amatha kukhala ndi zidutswa 60 kapena 20.
• Mu dragee (400 ndi 100 mg). Mu paketi amodzi mwa makatoni pamakhoza kukhala zidutswa 60 kapena 20.
• Mapiritsi otulutsidwa (600 ndi 400 mg), omwe amakhala ovomerezeka ndipo amakhala ndi mzere wogawa. Makatoni oikidwa nthawi zambiri amakhala ndi zidutswa 50.
• Mu ma ampoules omwe ali ndi jakisoni. Kuphatikizika kwa mankhwalawa kumaphatikizapo pentoxifylline, komanso sodium chloride ndi madzi.

Zotsatira za pharmacological

Kodi Pentoxifylline ali ndi katundu wotani? Analogue ya chida ichi ali ndizofanana ndi mankhwalawo pawokha. Ndi m'gulu latsopanolo la hemorheological othandizira. Imatha kubwezeretsa kuchuluka kwa maselo ofiira am'magazi ndikuchepetsa kuwonongeka kwawo. Izi zimawonjezera kupezeka kwamitsempha yamagazi yomwe imakhala ndi kuwala pang'ono.

Katundu wa mankhwalawa amachititsa kuti magazi azikhala ochepa, zomwe zimakhudza minyewa nthawi yayitali.

Kodi Pentoxifylline amagwira ntchito bwanji? Analogues ochokera kunja ndi Russian ali ndi achire ofanana ndi chida chokha. Mukatha kugwiritsa ntchito mankhwalawa, amachepetsa kusakanikirana kwa maselo ofiira, omwe pambuyo pake amawonjezera magazi mu ziwalo ndikulowetsa kama.

Ndizosatheka kunena kuti mankhwalawo omwe amafunsidwa amachepetsa kukhuthala kwa magazi, potero amathandizira kuti magawo azigawika. Zotsatira zamphamvuzi za mankhwalawa, miniti ndi ma stroke ochepa omwe magazi amawonjezeka, koma zowonetsa zamtima sizisintha.

Chifukwa chake, kufalikira kwa ziwiya zam'mapapu kumathandizira kudzaza kwa magazi a O 2, ndikukula kwa mitsempha ya coronary kumawonjezera kutumiza kwa O 2 kupita ku myocardium.

Mankhwala omwe amafunsidwa amatha kukulitsa kamvekedwe ka diaphragm ndi minofu yopuma.Mothandizidwa ndi iye, kuchuluka kwa magazi omwe amayenda m'mipangiri kumawonjezeka, ndipo magazi amayenda mkati mwake akuchuluka.

Ndi zinthu zina ziti zomwe Pentoxifylline ali nazo? Kuthandizira kwa mankhwalawa ndi mankhwalawo pawokha kumakulitsa kuchuluka kwa ATP muubongo, komanso kusintha kayendedwe ka magazi m'malo osokonezeka (mwachitsanzo, ndi ischemic stroke).

Tiyeneranso kudziwa kuti mankhwalawo omwe atchulidwa ali ndi zotsatira zabwino pa mtima wamanjenje ndi ntchito yake. Chifukwa cha kuwonongeka kwa mitsempha yotupa, kugwiritsa ntchito kothandizirawa kumawonjezera kuyenda mtunda, kuphatikizapo matenda monga kufalikira kwa endarteritis.

Zizindikiro za Pharmacokinetic

Pentoxifylline amatenga nthawi yayitali bwanji? Malangizo ogwiritsira ntchito (ma fanizo a mankhwalawa alembedwa pansipa) amatidziwitsa kuti mankhwalawa ali ndi luso lofika, kuphatikizira kudzera mu chotchinga cha ubongo.

Hafu ya moyo wa mankhwala ndi mtsempha wama mtsempha kwamphindi 30. Mukamamwa mankhwalawo mkati, zimangotsala pang'ono kugaya.

Mankhwala amasinthika m'chiwindi, komwe amapanga dimethylxanthine metabolites. M'magazi, pazipita kuchuluka kwa mankhwalawa kumafika maola 4 mutatha kugwiritsa ntchito. Kuphatikiza apo, amakhalabe pamankhwala osakhalitsa pafupifupi tsiku limodzi.

Mankhwalawa amachotseredwa makamaka ndi impso (pafupifupi 95%). Kudzera m'matumbo, mankhwalawa amatuluka pang'ono.

Mwa akazi, omwe amayamwitsa, mankhwalawa amatha kuchotseredwa mkaka pamodzi ndi mkaka. Tiyeneranso kudziwa kuti kuchotsedwa kwa mankhwalawa kumachepetsedwa kwa odwala omwe ali ndi matenda oopsa a impso, chiwindi ndi okalamba.

Zizindikiro zogwiritsidwa ntchito

Kodi wodwala angafotokozere Pentoxifylline pazifukwa ziti? Ma Analogs ndi choloweza mmalo mwa mankhwalawo ali ndi zofananira zomwe zimagwiritsidwa ntchito.

Pakadali pano, mankhwala othandiza ngati amenewa amagwiritsidwa ntchito pochiza matenda ambiri. Tiyeni tiwayike pamndandanda pompano:

Njira zogwiritsira ntchito

Kodi Pentoxifylline amagwiritsidwa ntchito bwanji? Malangizo ogwiritsira ntchito, ndemanga (zoyerekeza za chida ichi zingakhale ndi Mlingo wambiri) ndi madotolo odziwa zambiri amati mankhwalawa amatengedwa pakamwa komanso kwa makolo (kutengera kuuma kwa matendawa).

Kukonzekera kwamlomo wamankhwala kumayamba ndi 200 mg (ndiye kuti, mapiritsi 2 katatu patsiku, mukatha kudya). Mukakwaniritsa zochizira, kuchuluka komwe kukuwonetsedwa kumatsitsidwa. Njira ya mankhwala ndi mapiritsi sayenera kupitirira mwezi umodzi.

Woopsa ndi matenda owopsa a ziwalo zamkati, mankhwalawa ndi mankhwala opatsidwa. Pali njira ziwiri zoperekera mankhwala: mtsempha wa magazi ndi mtsempha. Njira yoyamba imachitika pogwiritsa ntchito dontho. Kuti muchite izi, gwiritsani ntchito 1 ampoule pa 250 ml kapena sodium chloride. Mlingo womwe akuwonetsedwa umaperekedwa mkati mwa 2 maola.

Koma intra-ochepa makonzedwe a mankhwala, zotchulidwa muyezo wa 0 ga g pa 50 ml ya sodium mankhwala enaake.

Zotsatira zoyipa

Zina mwazotsatira zoyipa ndizotsatira:

• chizungulire, nkhawa, kugona kugona, kukokana, kusintha kwa mutu, mutu,
• kuchuluka kwa cholecystitis, kuchuluka kwa chiwindi transaminases, kukula kwa cholestatic hepatitis,
• kusanza, kumverera kwadzaza m'mimba, nseru, kutsegula m'mimba, kusowa chilakolako cha chakudya,
• urticaria, anaphylactic, kuyabwa, redness khungu la nkhope,
• kupezeka kwa arrhythmias, kupweteka kwa mtima, kuchepa kwa magazi, angina pectoris,
• thrombocytopenia, leukopenia,
• malo okhala, kuwonongeka kowonekera,
• kuchuluka kwa mphumu ya bronchial, bronchospasm, kulephera kupuma,
• magazi a mitundu yambiri.

Mankhwala "Pentoxifylline": analogues, mtengo

Mankhwala otsatirawa ndi fanizo la mankhwala omwe amafunsidwa:

• mapiritsi "Agapurin" (100 mg), komanso yankho la jakisoni mu ma ampoules (100 mg),
• mapiritsi okhala ndi "Vazonit" (600 mg),
• mapiritsi, mapiritsi ndi jakisoni wa Trental.

Tiyenera kudziwa kuti Trental ndi mankhwala oyamba. Amalembedwa kwa odwala omwe ali ndi encephalopathies ochokera kosiyanasiyana.

Ponena za mtengo, ndiye pa mankhwala onse omwe atchulidwa, ndizosiyana. Analogue ya Trental Pentoxifylline ingagulidwe kwa ma ruble 120, mankhwala oyamba a ruble 520, Agapurin a ruble 300, ndi Vasonit ma ruble 400.