Mankhwala cholestyramine: malangizo, ntchito, analogi ndi ndemanga

Kusintha kwa odwala omwe ali ndi cholesterol yambiri yamthupi ndi kuwonongeka kwa ma asidi a bile kuchokera mthupi, kugwiritsa ntchito mankhwala apadera. Chodziwika kwambiri mwa izi ndi Cholestyramine. Malangizo ogwiritsira ntchito kuti mupeze kuti mankhwalawa amalekeredwa bwino, chifukwa samachokera m'matumbo ndipo samakhudza kugwira ntchito kwa ziwalo zina ndi machitidwe ena. Koma zimadziwika ndi odwala makamaka kuchokera kwa odwala ena omwe adalandira mankhwalawa. Zowonadi, tsopano "Cholestyramine" sichigwiritsidwa ntchito konse ngati mankhwala aku Russia. Chifukwa chake, musanagwiritse ntchito mankhwalawa, muyenera kufunsa dokotala.

Zochita zamankhwala

"Cholestyramine" ndi anion exchange resin insoluble m'madzi.

amachepetsa mafuta m'thupi,
amachepetsa zomwe zili lipoproteins ndi triglycerides,
Amachita bwino kupanga ma asidi amadzimadzi kuchokera ku cholesterol m'chiwindi,
Imachepetsa kuyabwa khungu chifukwa cha kusokonezeka kwa ndulu.

Zizindikiro zogwiritsidwa ntchito

Sikuti odwala onse omwe ali ndi cholesterol yowonjezera amadziwa bwino phindu la mankhwalawa "Cholestyramine". Malangizo ogwiritsira ntchito amalimbikitsa kuti mugwiritse ntchito pazinthu zotere:

popewa matenda a atherosulinosis,
ndi matenda a mtima kupewetsa kulowetsedwa kwa mtima,
ndi cholesterol yayikulu magazi,

Pazochitika zonsezi, mankhwalawa amakhala othandiza.

"Cholestyramine": malangizo ogwiritsira ntchito

Mtundu womasulidwa wa mankhwalawa ndi ufa wokonzekera kuyimitsidwa. Kuti musungunuke, muyenera kutenga theka kapu yamadzi.

Contraindication ndi zotheka zovuta

Ngakhale kuti mankhwalawo amatetezedwa komanso momwe amathandizira thupi, sikuti aliyense akhoza kumwa Cholestyramine. Malangizo ogwiritsira ntchito amaletsa kugwiritsa ntchito pazinthu zotere:

ndi chotchinga m'mimba,
odwala phenylketonuria,
pa mimba ndi kuyamwa,
ndi tsankho laumwini.

Mosamala, mankhwalawa amalembedwa kwa anthu okalamba azaka zopitilira 60 ndi ana, popeza ali ndi chiopsezo chokhala ndi mavuto. Nthawi zambiri, zotsatira zoyipa zimawonetsedwa ndimatumbo am'mimba: nseru, kusanza, matenda am'mimba, kutentha kwa mtima ndi kuphwanya mtima. Mankhwalawa amatha kuyambitsa magazi, chifukwa amachepetsa m'magazi a m'magazi. Pakhoza kukhalanso malabsorption mavitamini ena osungunuka a mafuta ndi acid. Ndi mankhwala osokoneza bongo, kutsekeka kwa m'mimba kumatha kuyamba. Koma kwenikweni, mankhwalawa "Cholestyramine" amaloledwa bwino (malangizo ogwiritsira ntchito ali ndi chidziwitso cha izi).

Kukonda kwa mankhwala

Palibe mankhwala ambiri okhala ndi vuto lofananalo. Nthawi zambiri amakhala ndi mawonekedwe ofanana. Malangizo a "cholestyramine" wa mankhwala ogwiritsira ntchito amatchedwa othandiza kwambiri. Mutha kugula izi pansi pa mayina "Kolestir", "Questran", "Cholestan" ndi "Kolestiramin." Kuchita kotereku kumakhalanso ndikukonzekera: Lipantil, Ezetrol, Tribestan, Ipokol ndi ena. Koma funso la kusankha mankhwala liyenera kuganiziridwa ndi adokotala. Kupatula apo, onse ali ndi zotsutsana zosiyanasiyana komanso zoyipa.

Ndemanga pa "Cholestyramine"

Mankhwalawa ndiokwera mtengo kwambiri: phukusi la 100 Mlingo lingagulidwe kwa ma ruble a 1000-1500. Izi ndichifukwa adalamulidwa ku Germany ndikupulumutsidwa mwachindunji kuchokera kwa wopanga. Tsopano mankhwalawa sanalembetsedwe ku Russian Federation. Koma ngakhale izi zili choncho, odwala ambiri amapeza chithandizo cha "Cholestyramine". Malangizo ogwiritsira ntchito, ndemanga zokhudzana ndi mankhwalawa komanso zotsatira zake zoyipa zimakhala pamavuto ambiri. Odwala omwe adathandizidwa ndi wothandizirawa, akuwonetsetsa kuti zinthu zikuyenda bwino komanso kuti palibe mavuto omwe amayambitsidwa. Mankhwalawa amalekeredwa bwino, amasintha kagayidwe ndipo amakonza magwiridwe antchito a chiwindi ndi ndulu.

Limagwirira a zochita za mankhwala

Cholestyramine (Colestyramine) amapangidwira bile bile acid m'matumbo. Awa ndi adsorbent, otchedwa ionic kapena ion-exchange resin, omwe amatha kulowa pazosinthana ndi mayankho ion. Mankhwala ndi a gulu la bile acid sequestrants.

Limagwirira ntchito ya sequestrants ndikoletsa yachilendo njira kuwola ndi kuchira kwa bile acids wolemera mu mafuta. Kamodzi m'matumbo, mankhwala amalowa m'magulu a mankhwala omwe amapezeka ndi bile acids, ndikupanga zovuta zomwe sizimalowa mu thupi, koma zimangotulutsidwa. Poyankha izi, kuphatikiza kwa cholesterol m'chiwindi kumawonjezeka, koma nthawi yomweyo mawonekedwe ake amaphatikizidwanso.

Mukayika pambali mankhwala, njira yonseyo imawoneka ngati iyi: ma asidi amaphatikizidwa m'chiwindi ndi cholesterol, ambiri mwa asidi omwe amalowa m'matumbo amadzipaka m'magazi ndikubwerera ku chiwindi kuti atenge nawo gawo limodzi la bile. Ngati gawo la asidi sililowa m'magazi, koma litulutsidwa m'thupi, chiwindi chimakakamizidwa kugwiritsa ntchito cholesterol amana. Chifukwa chake, cholestyramine imathandizira kuwonjezera kuchuluka kwa bile acid komanso kumachepetsa cholesterol yonse mthupi.

Zofunika! Kuchepa kochepa kwa cholestyramine kuphatikiza kulekerera bwino kumabweretsa kuchepa kwapang'onopang'ono pakugwiritsa ntchito kwake. Ku Russia, mankhwalawa sagwiritsidwa ntchito ngati mankhwala.

Chifukwa chiyani cholestyramine imalembedwa?

Mankhwalawa amakhudza kwambiri cholesterol yotchedwa "yoyipa" - lowensens lipoproteins (LDL). Izi zimachepetsa chiopsezo cha:

matenda amtima
atherosulinosis (mitsempha yotsekeka ndi zolembera za cholesterol).

Chidacho ndichofunikanso:

Kuchepetsa kuyamwa ndi kupindika pang'ono kwa ndulu,
monga chowonjezera pazakudya zomwe cholinga chake ndi kutsitsa cholesterol.

Monga adsorbent, Cholestyramine siili yofanana ndi Smecta, chifukwa mosiyana ndi iwowo, kugwira kwake ntchito kumadalira acidity yankho: kukwera kwa acidity, ndikoipa kwambiri komwe kumagwiranso ntchito.

Zofunika! Mankhwalawa sayenera kumwedwa ndi matenda obadwa nawo a amino acid (phenylketonuria), panthawi yoyembekezera komanso mkaka wa m`mawere.

Malangizo ogwiritsira ntchito

Mwachizolowezi, cholestyramine imatulutsidwa mu mawonekedwe a ufa kukonzekera kuyimitsidwa. M'thumba limodzi 4 g yazogulitsa, mu phukusi - 0,5 kg. Chofunikira kwambiri ndi utoto wopangira utomoni wa colestyramine. Zabwino zake ndi sucrose, citric acid, mitundu ya chakudya ndi owongoletsa.

Pa gawo loyambirira logwiritsira ntchito, kuyimitsidwa kumatengedwa musanadye kamodzi kamodzi kapena kawiri pa tsiku. M'tsogolomu, kusinthasintha kwa madongosolo kumawonjezeka mpaka atatu. Koma mlingo umadalira makamaka momwe wodwalayo alili, kupezeka kapena kusapezeka kwa matenda ena, kulekerera kwa mankhwalawo, kufunika kophatikiza maphunziro angapo a mankhwalawa. Ndiye kuti, maphunzirowa akuyenera kuwerengedwa ndi dokotala potengera mbiri ya wodwala. Pafupifupi, mlingo wa 8-6 g umalimbikitsidwa, umagawidwa pakati Mlingo wa 2-3.

Pogwiritsa ntchito cholestyramine kwanthawi yayitali, vuto la mavitamini osungunuka la mafuta lingachitike. Chifukwa chake, pamodzi ndi mankhwalawa, mavitamini ovomerezeka nthawi zambiri amapatsidwa mankhwala. Ngati mankhwalawa atengedwa limodzi ndi ena othandiza pa mankhwalawa, amayenera kuti azitha kuledzera mosiyana ndi zomwe zimachitika: Maola 1-2 asanachitike kapena maola 4 atatha. Kugwiritsidwa ntchito mosiyanasiyana kumatha kusokoneza kuyamwa kwa mankhwala.

Zofunika! Gawo lolimbikira la cholestyramine silinalembedwe mwalamulo ku Russian Federation.

Mndandanda wa cholestyramine

Gulu la bile acid sequestrant, kuwonjezera pa cholestyramine, limaphatikizapo:

Colestipol (kumangika kumakhala koyipa pang'ono)
Colestipol (kuthekera bwino kumangirira, kusayanjana ndi mankhwala ena, zovuta zochepa).

Cholestyramine ndiye mankhwala oyamba m'gululi. Imatsitsa cholesterol yokwanira pafupifupi 20%.

Pakadali pano, m'mafakitala palibeogulitsa cholestyramine, koma pali fanizo:

Roxer - mtengo wake udachokera ku ma ruble 178.,
Lipantil - kuchokera 40 rubles.,
Lipantil 200M - kuchokera 871 rub.,
Vitrum Cardio Omega-3 - kuchokera 1250rub.

Mitengo ya mankhwala osokoneza bongo itha kusiyana pamadera. Ngakhale ma analogu ndi gulu limodzi la mankhwalawo, kusintha kwa cholestyramine ndi iliyonse mwa iwo kuyenera kuvomerezana ndi adokotala.

Malangizo a cholestyramine ufa

Malangizo omwe ali ndi chidziwitso chachidule chokhudza mankhwalawa amasindikizidwa mwachindunji pa phukusi ndi ufa / kuyimitsidwa kwa cholestyramine. Zambiri pazakugwiritsa ntchito bwino mankhwalawa zitha kupezeka m'mabuku kapena kwa dokotala.

Pharmacology

Makina amakono a cholestyramine ndi chifukwa cha kuthekera kwa bile bile acid m'matumbo ndi mapangidwe apangidwe a chelate zovuta kusungunuka, mwachilengedwe amachotsedwa m'thupi ndi ndowe.

Wothandizirayi amathandizira kuchepetsa kuyamwa kwa mafuta acids ndi cholesterol. Zimathandizanso kapangidwe ka bile acid mu chiwindi minofu ndi makina amachitidwe.

Chifukwa cha zotsatira za cholestyramine, lipoprotein yotsika kwambiri komanso kuchuluka kwa mafuta m'thupi amachepetsa kwambiri. Kuchuluka kwa mafuta acids kumakakamizidwa kuti athe kuyesedwanso m'matumbo, kuyambiranso m'chiwindi ndikumasungidwa ndi bile. Kuphatikiza ma asidi awa, chiwindi chimayamba kugwiritsa ntchito mafuta ochulukirapo.

Odwala omwe ali ndi vuto la metabolic la lipid chibadwa, pamene kuchuluka kwa cholesterol mu seramu yamagazi ndikachuluka, mankhwalawa amachepetsa vutoli pochepetsa milingo ya lipoprotein ndi cholesterol. Komanso, cholestyramine imathandizira kuthetsa kuyimitsidwa ndi zotsekeka zomwe zidalipo mwa ndulu za bile, kutsitsa zomwe zili asidi m'magazi, potero zimaletsa kuyika kwawo pakhungu.

Kuti achire akwaniritsidwe, chithandizo cha nthawi yayitali chimaperekedwa. Mankhwala akulimbikitsidwa kugwiritsa ntchito osachepera mwezi. Kuchita chithandizo choterocho kumafunikira kuwunika momwe wodwalayo amapangira folic acid mu kapangidwe ka maselo ofiira am'magazi ndi magazi, komanso kuwunika momwe chimbudzi chikupangidwira komanso kutha magazi.

Zotsatira zoyipa

Kutenga cholestyramine kwa wodwala kumakhala kovuta chifukwa cha zovuta zina. Madandaulo otsatirawa adalandiridwa kuchokera kwa odwala omwe amamwa mankhwalawa:

Pakakhala mankhwala azitali, odwala adati:

magazi a m'matumbo,
vuto la magazi,
chitukuko cha zotsekemera m'mimba,
kupezeka kwa magazi mkati mwa malo a duodenum / m'mimba,
kukula kwa acidosis ya hyperchlorimia.

Kupanga ndi mawonekedwe a kumasulidwa

Mu cholestyramine, mawonekedwe omasulidwa ndi mapiritsi ndi ufa, womwe umagwiritsidwa ntchito pokonzekera kuyimitsidwa kwamankhwala. Amagwiritsidwa ntchito mkati.

Gawo lalikulu la mankhwalawa ndi colestyramine. Pambuyo kulowa mkatikati mwa thupi, ma asidi a bile amayamba kumanga m'mimba. Chifukwa cha njirayi chelate zovuta zimawonekera - mankhwala osakwanira.

Chifukwa cha zomwe zigawo zomwe zimagwira, kuchuluka kwa mafuta acid, cholesterol imachepetsedwa ndipo njira yopanga ma bile acids imayambitsidwa.

Ndi bile blockage, kuyabwa kuyimitsidwa. Kuti mukwaniritse izi, mankhwalawa amayenera kumwedwa kwa nthawi yayitali. Nthawi zambiri, njira yochiritsira imatha mwezi umodzi. Chifukwa cha kuchuluka kwa mankhwalawa kwa mankhwalawa, kuchuluka kwa folic acid kumachepa, njira yotseka imasokonekera.

Munthawi ya chithandizo, katswiri amayenera kuwunika momwe wodwalayo alili ndikuwunika maphunziro onse ndikusanthula.

Chosakaniza chophatikiza sichikhala ndi poizoni m'thupi la wodwalayo chifukwa chakuti sichiyipa m'matumbo. Kuchuluka kwa mankhwalawa m'magazi kumafika ola limodzi mutatha kumwa mankhwalawo.

Zizindikiro ndi contraindication

Musanagwiritse ntchito mankhwalawa, ndikofunikira kuphunzira malangizo ogwiritsira ntchito mankhwalawa, popeza ali ndi zisonyezo zina ndi zotsutsana ndi ntchito. Mankhwala wololeza kuti apangidwe monga:

kuledzera kwa digito,
matenda a mtima
kupewa myocardial infarction, atherosulinosis,
cholesterol yayikulu mthupi,
kupezeka kwa kuyabwa chifukwa cha kusayenda kwa ndulu,
cholelithiasis.

Mankhwala sangathe kugwiritsidwa ntchito ndi hypersensitivity pazinthu zomwe zimapanga mankhwalawa, pamene mukuyamwitsa ndi kubereka mwana, ndikulepheretsa njira yothandizira. Mosamala kwambiri komanso moyang'aniridwa ndi dokotala, mankhwalawa amamwa munthu ali ndi zaka 60. Mankhwala ali kuchuluka kwa zotsatira zoyipa. Izi zikuphatikiza:

kutsegula m'mimba
kudzimbidwa
kuchepa kwamtima
chisangalalo
kapamba
kupweteka m'mimba
mavitamini akumwa ndi mavitamini,
kuchuluka libido
acidosis
zotupa pakhungu.

"Cholestyramine": malangizo ogwiritsira ntchito

Mtundu womasulidwa wa mankhwalawa ndi ufa wokonzekera kuyimitsidwa. Kuti musungunuke, muyenera kutenga theka kapu yamadzi. Madzi ndi abwino, koma mutha kumwa mankhwalawo ndi msuzi kapena mkaka. Kuyimitsidwa kumakonzedwa mphindi 10 isanayambike, popeza ufa umayenera kusungunuka bwino. Mlingowo umatsimikiziridwa ndi adotolo malinga ndi thanzi la wodwalayo. Nthawi zambiri 4 magalamu a mankhwala amaperekedwa kawiri pa tsiku. Koma mlingo utha kuwonjezeredwa mpaka 4 mg wa 4. Muyenera kumwa "Cholestyramine" musanadye. Njira ya mankhwala ndi mankhwala osachepera mwezi. Panthawi imeneyi, muyenera kumwa madzi ambiri momwe mungathere ndikuwongolera kuchuluka kwa prothrombin ndi folic acid. Nthawi zina, mavitamini owonjezereka akuwonetsedwa, makamaka vitamini K. Ngati wodwala akutenga mankhwala ena, tikulimbikitsidwa kuti azitha kuledzera maola 4 pambuyo pa Cholestyramine.

Ndemanga pa "Cholestyramine"

Mankhwalawa ndiokwera mtengo kwambiri: phukusi la 100 Mlingo lingagulidwe kwa ma ruble a 1000-1500. Izi ndichifukwa adalamulidwa ku Germany ndikupulumutsidwa mwachindunji kuchokera kwa wopanga. Tsopano mankhwalawa sanalembetsedwe ku Russian Federation. Koma ngakhale zili choncho, odwala ambiri amapeza chithandizo cha "Cholestyramine". Malangizo ogwiritsira ntchito, ndemanga zokhudzana ndi mankhwalawa komanso zotsatira zake zoyipa zimakhala pamavuto ambiri. Odwala omwe amathandizidwa ndi wothandizirawa, akuwonetsetsa kuti zinthu zikuyenda bwino komanso kuti palibe mavuto omwe amayambitsidwa. Mankhwalawa amalekeredwa bwino, amasintha kagayidwe ndipo amakonza magwiridwe antchito a chiwindi ndi ndulu.

Cholestyramine: mawonekedwe a kumasulidwa, mawonekedwe ndi zotsatira zake

Gawo lalikulu la mankhwalawa ndi cholestyramine anion exchange resin, lomwe silisungunuka m'madzi. Kapangidwe ka cholestyramine mulinso zigawo za polymer zomwe zimapangidwa ndi styrene ndi divinylbenzene mankhwala.

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Zigawozi sizimadziwika ndi mayamwidwe, ndipo iwo, atamangirira ku zigawo za cholesterol ndi asidi a bile, amachotsedwa popanda kusintha mawonekedwe awo. Ndi njira imeneyi yomwe imayambitsa zomwe Cholestyramine amagwira.

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Pofotokoza momwe mankhwalawa amathandizira thupi, mfundo zotsatirazi zitha kudziwika:

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chifukwa cha zomwe chinthu chachikulu komanso zinthu zina zomwe zimapanga cholesterol, pali kuchepa kwakukulu kwa cholesterol,
pali kuchepa msanga kwa kuchuluka kwa lipoproteins ndi triglyceride mankhwala,
amalimbikitsa mapangidwe a bile acids, omwe amasinthidwa chifukwa cha kuwonongeka kwa cholesterol m'magazi a chiwindi,
amathetsa mawonekedwe a kuyabwa kwa khungu, komwe kumawonekera chifukwa cha kusalinganika pantchito ya ndulu.

Mukamapereka mankhwala, mu mankhwala achi Latin dzina la Cholesteramine. Nthawi zambiri, malonda amapezeka mu mawonekedwe a ufa, womwe umapangidwira kukonzekera kuyimitsidwa. Palinso mapiritsi olemera 4 g.

Cholestyramine: mavuto

Mukamagwiritsa ntchito mankhwala a Cholestyramine monga njira yochizira, Mutha kukumana ndi izi:

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kudzimbidwa
mawonekedwe a ululu mu epigastrium,
chisangalalo ndi kuphuka,
akukumbutsa
nseru
maonekedwe a mafuta odzaza ndi ndowe,
kutentha kwa mtima
kudzimbidwa
kusowa kwa chakudya
mawonekedwe a pakhungu pakhungu,
mawonekedwe a kutupa kwa kapamba,
kukulitsa chilakolako chogonana.

ku nkhani zake ↑

Momwe mungagwiritsire ntchito cholestyramine

Mankhwala a Cholestyramine amathandizidwa pakamwa, mosasamala mawonekedwe a mankhwalawa. Mlingo komanso nthawi yayitali ya maphunzirowa imangokhazikitsidwa ndi katswiri, popeza wodwalayo ndi munthu payekha.

Ngati mankhwalawo agulidwa mu mawonekedwe a ufa, ndiye kuti kuyimitsidwa kuyenera kukonzedwa ndikuphatikiza mankhwalawa ndi madzi, madzi kapena mkaka. Kuchuluka kwa madzi pokonzekera ndi 50-80 ml. Kuyimitsidwa kukakonzeka, kuyenera kusiyidwa kwa mphindi 10 musanagwiritse ntchito. Kudzinyenga kotero kumachitika kuti ukwaniritse chinthu cha ufa ndi madzi.

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Mukamagwiritsa ntchito mankhwala a Cholestyramine, ndikofunikira kukumbukira kuti ndizoletsedwa mopitilira muyeso womwe adokotala adauza. Izi zimalonjeza mawonekedwe a kutsekeka m'mimba. Ngati wodwala akukumana ndi zoopsa zotere, ndikofunikira kuyimba ambulansi posachedwa ndikusiya kugwiritsa ntchito Cholestyramine.

Chofunikira ndikutsatira boma lakumwa. Nndikofunikira kumwa madzimadzi ambiri momwe mungathere potenga Cholestyramine ndikuwunika kuchuluka kwa cholesterol triglyceride mankhwala m'magazi.

Ndemanga za Odwala

Mankhwalawa ali ndi ndemanga zochepa, amakhala abwino.

Ndinafunika kugwiritsa ntchito mankhwalawa nditalandira mayeso a cholesterol. Ndinadabwa kwambiri ndi zotsatirazi, chifukwa sindimayembekezera kuti nditenga mankhwalawa. Ndimalimbikitsa kwambiri kwa aliyense. Ndipo analogue idathandizanso. Musanatenge Questran, ndikupangira kuti muphunzire malangizo omwe mungagwiritse ntchito.

Ndinagula mankhwalawa m'sitolo yapaintaneti, chifukwa simunali mumafakitore. Zotsatira zake za kumwa mankhwalawa zilidi. Ndikufuna kuchenjeza za kukhalapo kwa zoyipa zingapo. Musanagwiritse ntchito mankhwalawa, onetsetsani kuti mwawonana ndi dokotala.

Mzanga adandiwuza ine cholestyramine. Chifukwa cha kulandira kwake, mkhalidwe wanga wayenda bwino kwambiri. Mutatha kugwiritsa ntchito mankhwalawa kamodzi, mayesowo adawonetsa cholesterol yabwinobwino m'magazi.

Cholestyramine: malangizo, analogi, mtengo, ndemanga

Zochita Zamankhwala

Mukaphatikiza mankhwalawa ndi ena mwa mankhwalawa, machitidwe omwe mungagwiritsire ntchito mankhwalawa:

ndi furosemide - mphamvu yake yotsitsa imachepa,
sulindac / raloxifene - mayamwidwe awo amachepetsedwa ngakhale pakhale pakati pakumwa mankhwalawo.
levothyroxine (mahomoni a chithokomiro) - mphamvu zawo zimachepa,
phenylbutazone / iron sulfate - kuchepa kwathunthu kwa plasma ndende,
hydrochlorothiazide - kuthekera kwa kuyamwa ndi kuchepa kwa mphamvu kumachepa,
vancomycin - imataya mphamvu,
amiodarone - kuchuluka kwa magazi a mankhwalawa,
ma tridclic antidepressants - kuphatikizika kwa plasma kumachepa,
acarbose - kugwira kwake kumawonjezera,
hydrocartisone, sodium valproate, glipizide, anticoagulants - kugwira kwawo kumachepa,
ibuprofen, diclofenac - kuthekera kwawo kuyamwa kumachepa,
loperamide, paracetamol, metronidazole, metatrexate - zotsatira zawo zimachepa,
piroxicam, meloxicam, tenoxicam - kuwachotsa m'thupi mwachangu,
spironolactone - nthawi zambiri ndi kuphatikiza uku, hypochloric alkalosis imayamba.

Ndemanga za Cholestyramine

Cholestyramine sichimakonda kutchulidwa, koma moyenera. Awa ndi mankhwala okwera mtengo komanso osagwiritsidwa ntchito masiku onse m'mankhwala apakhomo.

Marina: Ngakhale adachenjezedwa za zovuta zoyipa, adalandira chithandizo cha mankhwala a cholestyramine. Ndikutha kudziwa kuti ziwengo ndi zovuta sizinandivutitse, koma ndinatha kukhazikitsa kagayidwe. Chida ichi ndiokwera mtengo koma zotsatira zabwino ndizowonekera.

Taisia: Magwiridwe anga a chiwindi ndi w / chikhodzodzo anali operewera kwambiri. Dotolo adalimbikitsa chithandizo ndi cholestyramine, koma sanamuike. Ndanena za zovuta zomwe zingachitike komanso kuwononga kwa mankhwalawo. Komabe, ndinapeza. Zowona, ndimayenera "kuyenda" mozungulira mankhwala azamalonda a pa intaneti. Sindikudandaula. Mankhwalawa adathandizadi.

Snezhana: Ndi mankhwala a cholesterol mwa mwamuna wake, mankhwalawa anali ololedwa bwino. Analimbikitsidwa kuti azimwa mankhwala awa kwa mwezi umodzi kuti apewe zovuta pambuyo pa vuto la mtima.

Zotsatira zoyipa zinali mu mawonekedwe a mseru ndi kudzimbidwa, koma sizowopsa. Chinthu chachikulu tsopano akumva bwino ndipo atha kukhala ndi moyo wamphumphu. Timalimbikitsa chida ichi kwa iwo omwe adotolo awalangize. Osakana.

Chipangizocho ndiokwera mtengo, koma chothandiza.

Diarol: malangizo ogwiritsira ntchito

Hydrasec: malangizo, mtengo, analogi

Mapiritsi a Norbactin: malangizo, ndemanga

Octreotide: malangizo, ndemanga

Vero-Loperamide: ndemanga, malangizo

Kufotokozera kwa mankhwala Cholestyramine

Hypercholesterolemia ndi chiyani? Chi Greek chimamasulira kuti cholesterol yapamwamba. Izi ndizodziwika ndi matendawa. Hypercholesterolemia sindiwo matenda, koma matenda am'mimba.

M'malo mwake, hypercholesterolemia ndiyomwe imayambitsa zovuta zambiri pakugwira ntchito kwa mtima ndi mitsempha yamagazi. Ngati muli ndi mawonekedwe a izi, ndiye kuti muyenera kufunsa kuchipatala mwachangu kuti mupeze thandizo.

Nthawi zina, dokotala amakupangira cholestyramine kuchiza matenda. Kodi njira yothetsera vutoli ndi iti?

Momwe mungamwe mankhwalawa?

Kutalika konse kwa chithandizo chamankhwala ndi kuchuluka kwa mankhwalawa kungathe kutsimikiziridwa ndi adokotala.

Ufa uyenera kutengedwa pakamwa. Iyenera kutengedwa musanakhale pansi kuti mudye. Supuni ya ufa iyenera kusakanizidwa ndi madzi, msuzi kapena zonona. Kusagwirizana komwe kumachitika kuyenera kusakanikirana ndikuledzera Mphindi 10 atatha kusakaniza.

Monga lamulo, kuchuluka kwa zakudya patsiku sikupitirira 2 times, koma nthawi zina kumatha kuwonjezeka mpaka 4. Ngati mankhwalawa adapangidwanso ndi mankhwalawa, ndiye kuti maola 4 okha ayenera kudutsa pakati pawo.

Kuphatikiza ndi mankhwala ena

Mankhwala amachepetsa diuretic kwenikweni pamene akumwabe ndi furosemide.
Mankhwalawa amachepetsa kuyamwa kwa raloxifene ndi sulindac.
Pankhani ya munthawi yomweyo makonda a levothyroxine kapena mahomoni ena a chithokomiro omwe ali ndi mankhwala, kugwiritsa ntchito mphamvu yomaliziraku kumachepetsedwa kangapo.

Mankhwala amalimbikitsa mphamvu ya acarbose.

Mankhwalawa amachepetsa mphamvu ya warfarin, fenprocoumone, dicumarol, ethyl biscum acetate, glipizide.

Sitikulimbikitsidwa kuti mutenge ndi diclofenac kapena ibuprofen nthawi yomweyo.

Mankhwalawa amatha kuchepetsa mphamvu ya paracetamol, methotrexate, metronidazole.

Mimba

Ngati mayi ali woyembekezera kapena woyamwitsa, ndiye kuti mankhwala saloledwa. Kuchita koteroko kumalumikizidwa ndi chakuti zinthu zomwe zimagwira zimatha kukhala zowononga osati kwa mkazi, komanso kwa mwana wake wosabadwa.

Chifukwa cha kuwonekera kotere, mwana amabadwa ndi matenda osiyanasiyana.

Kuphatikiza apo, ngati mtsikana akufuna kukhala ndi pakati, ndiye kuti mwezi umodzi asanakhale ndi pakati, mankhwalawo amaleka.

7. Momwe mungasungire bwino mankhwala?

Mankhwalawa amayenera kusungidwa pa kutentha kwa madigiri 15 mpaka 25 m'chipinda momwe chikhala chouma komanso chopanda. Nthawi yomweyo, ndikofunikira kuti ana ang'onoang'ono mulimonse sangapeze mankhwalawa. Malo abwino osungirako akhoza kukhala shelufu patebulo la kama.

Tsiku lotha ntchito likuwonetsedwa pamaphukusi. Ndikofunika kwambiri kuti musagwiritse ntchito mankhwalawa tsiku lawo likatha.

Kutengera ndi dera, mtengo wake umatha kusiyanasiyana. Ichi ndichifukwa chake cholembacho chikuwonetsa kuchuluka kwa mankhwalawo.

Mtengo wa mankhwalawa ku Russia kuyambira 3200 mpaka 3650 rubles

Ku Ukraine mankhwalawa amatenga pafupifupi 1,500 hryvnia.

Ku Russia, ma analogu sanatchulidwe, kale panali mankhwala a Questran.

Mankhwala monga Atoris, Vasilip, Krestor ali pafupi ndi mankhwalawa.

Ngati mwadziwa mwadzidzidzi kugwiritsa ntchito mankhwalawa, chonde siyani ndemanga yanu. Ndizotheka kuti lingaliro lanu lipange chisankho kwa munthu amene akukumana ndi chisankho.

Nthawi zambiri anthu amalabadira mankhwalawa. Amakondwera kuti mankhwalawa amayamba kuchita mwachangu momwe angathere. Kuphatikiza apo, ali okondwa kuti mankhwalawa ali ndi mndandanda wocheperako wa zotsutsana, ndipo zoyipa ndizosowa kwambiri.

Mwa mphindi, mtengo wa mankhwalawo ndiwokwera. Kuphatikiza apo, mankhwalawa ndizovuta kwambiri kulowa m'masitolo, chifukwa odwala amakakamizidwa kuti aziwongolera kudzera m'masitolo a pa intaneti.

Pali maupangiri omwe simuyenera kuwanyalanyaza. Ganizirani izi:

Musanayambe nthawi yopangana, upangiri waukatswiri umafunika.
Mankhwala osokoneza bongo.
Palibe chifukwa choti mutenge ufa uli pamalo owongoka.
Ngati mwadzidzidzi, mutatenga zizindikiro, pali zizindikiro zomwe sizinali kalepo, ndiye kuti mankhwalawo amayimitsidwa.
Mukakalamba, kusintha kwa mankhwala kungafunikire.
Chidziwitso chonse chomwe chaperekedwa pano chitha kugwiritsidwa ntchito pazophunzitsira zokha.
Ndi kusiyiratu kukamwa kwa mankhwalawo, matendawo obwera sangachitike.
Mukamamwa mankhwalawa, muyenera kuwonedwa ndi dokotala.

Kodi nkhaniyo inali yothandiza? Mwina izi zithandiza anzanu! Chonde dinani chimodzi mwa mabataniwo:

Mankhwala cholestyramine: zikuonetsa ntchito, mtengo, ndemanga

Ngati wodwala wakweza cholesterol, ndiye kuphatikiza pazithandizo zosiyanasiyana, mankhwalawa amagwiritsidwa ntchito.

Chithandizo chodziwika bwino kwambiri ndi cholestyramine. Malangizo ogwiritsira ntchito adzakuthandizani kuzindikira kufunika kogwiritsa ntchito chinthucho, komanso kumvetsetsa momwe zimakhudzira thupi.

Pofotokoza momwe mankhwalawa amathandizira thupi, mfundo zotsatirazi zitha kudziwika:

chifukwa cha zomwe chinthu chachikulu komanso zinthu zina zomwe zimapanga cholesterol, pali kuchepa kwakukulu kwa cholesterol,
pali kuchepa msanga kwa kuchuluka kwa lipoproteins ndi triglyceride mankhwala,
amalimbikitsa mapangidwe a bile acids, omwe amasinthidwa chifukwa cha kuwonongeka kwa cholesterol m'magazi a chiwindi,
amathetsa mawonekedwe a kuyabwa kwa khungu, komwe kumawonekera chifukwa cha kusalinganika pantchito ya ndulu.

Mukamapereka mankhwala, mu mankhwala achi Latin dzina la Cholesteramine. Nthawi zambiri, malonda amapezeka mu mawonekedwe a ufa, womwe umapangidwira kukonzekera kuyimitsidwa. Palinso mapiritsi olemera 4 g.

Mawonekedwe ndi kipimo

Cholestyramine ndi m'gululi lipid-kutsitsa kukonzekera. Mwachilengedwe chake, ndi ion exchange resin.

Mosiyana ndi mapiritsi a mankhwala a statin, omwe tanthauzo lawo ndi kuthana ndi enzymatic yolumikizana ndi kusintha kwa cholesterol, cholestyramine imagwira mwachindunji m'matumbo enieni, ndikumanga ma asidi a cholic, monga tafotokozera mu malangizo.

Chifukwa chake, mankhwala osakwanira amapangidwa, omwe amatchedwa "chelate complexes" - samatengedwa ndi kuchotsedwa m'thupi.

Nthawi zambiri, cholestyramine wa mankhwala amapezeka mu mawonekedwe a hydrochloride, omwe amaphatikiza ndi copolymer (divinylbenzene ndi styrene). Malangizowo akuti nthawi zambiri mu cholestyramine mawonekedwe amamasulidwa ndi ufa. Kuchokera kwa iwo, mapiritsi kapena kuyimitsidwa kwakonzedwa, okonzeka kugwiritsidwa ntchito.

Ngati piritsi paperekedwa, ndiye kuti iyenera kumwedwa pakumwa asanadye. Ngati mankhwalawo adapangidwira mu mawonekedwe a ufa, ndiye kuti amafunikanso kumwa musanadye, koma osakanikirana ndi madzi kapena madzi, gwiranani bwino ndikuwulola kuti atuluke kwa mphindi 10.

Tsiku lililonse Mankhwala a cholestyramine amasankhidwa ndi akatswiri opezekapo kutengera mtundu womwe wapezeka ndi zotsatira za kuyesedwa kwa ma laboratori. Malinga ndi malangizo, mlingo woyambira tsiku lililonse umasiyanasiyana pakati pa 4 mpaka magalamu.

Imagawika m'magulu angapo - kuyambira awiri mpaka anayi patsiku. Kuti mukwaniritse zochizira zomwe mukuyembekeza, ziyenera kukhala zazitali komanso kukhala mwezi umodzi.

Munthawi yonseyi, muyenera kutsatira zakudya komanso malangizo onse azachipatala.

Gwiritsani ntchito pa nthawi yoyembekezera

Malinga ndi malangizo, Cholestyramine, monga ma ion ena osinthana ndi ion, sangathe kutumikiridwa panthawi yomwe ali ndi pakati ndikuyikayikira.

Pazoyeserera zamankhwala pazinyama, mankhwalawo adapatsidwa gulu "C", ndiye kuti, malinga ndi zotsatira za zoyesazi, umboni wamphamvu wa mankhwala opezeka mwana wosabadwa wakhazikitsidwa.

Komanso, singathe kulembedwera panthawi ya mkaka wa m'mawere, popeza imatha kulowa mkaka wa m'mawere.

Malinga ndi malangizo, m'mabukuwo mulibe deta yonse yokhudza kugwiritsa ntchito mankhwalawa m'zipatala za ana. Chifukwa chake, ana satchulidwa cholestyramine.

Kuchita ndi mankhwala ena

Monga tafotokozera, cholestyramine ili ndi zinthu zingapo zomwe zimapangitsa kuti mankhwala azigwirizana ndi mankhwala ena:

Mukumwa mankhwala ion osinthana ndi ma ion ndi ma diuretics - malupu (wogwiritsa ntchito furosemide - mankhwala "Lasix" ndi ena) ndi thiazide (yogwira mankhwala - hydrochlorothiazide, "Hypothiazide"), pharmacokinetics of diuretics. Awo okodzetsa zotsatira amachepetsedwa ngakhale mankhwalawa sitimadzipereka pakapita nthawi yoposa maola atatu.
Ndi chithandizo chammbuyo chokhala ndi anticomic vancomycin, zochita zaumwini zotayika zimatayika.
Cholestyramine imachedwetsa kuyamwa kwa phenylbutazone ndi sodium sodium.
Ndikulimbikitsidwa kwambiri kuti musamamwe ma bizinesi ion osinthiratu ndi nthawi imodzi. Kuphatikizika kwa mankhwalawa m'magazi am'magazi kumatsala pang'ono kutha, monga akuwunikira.
Ntchito zamankhwala okhala ndi L-thyroxine ndi mahomoni ena a chithokomiro amachepetsedwa kwambiri.
Simungathe kutumizira nthawi yomweyo cholestyramine ndi okodzetsa a gulu la aldosterone okonda - Veroshpiron. Malinga ndi malangizo, pogwiritsa ntchito njira yolumikizira, hypochloremic alkalosis imatha kukhala.

Mtengo wa mankhwala

M'gawo Russian Federation kulibe cholestyramine pamsika wogulitsa - sawerengedwa mdziko muno. Mutha kugula kokha mumasitolo ogulitsa pa intaneti. Mwa iwo, mtengo wa cholestyramine ndi mpaka ma ruble 1800. mapiritsi 12 ndi muyezo wa 4 g.

Ku Ukraine Utali wosinthanitsa wa ion uyu umalembetsedwa ndikugulitsidwa kuzipatala wamba. Mtengo wa cholestyramine kuchokera ku Canada wopanga Madokotala amachokera ku 750 mpaka 830 UAH pamapaketi 30 a ufa pa magalamu 9.

Kugwiritsa Ntchito

Ndemanga pakugwiritsa ntchito bwino kwa mankhwalawa kwa onse odwala ndi madokotala ndiwofanana, chifukwa limodzi ndi zotsatira zabwino zamankhwala, pali zovuta zingapo.

Vakulenko T.G., endocrinologist wa gulu lapamwamba kwambiri, Kiev. “Ndakhala ndikugwiritsa ntchito cholestyramine kwakanthawi. Si chaka choyamba kumsika wathu ndipo adziyambitsa chokha.

Zachidziwikire, mankhwalawa siwopsewa ndipo ndizosatheka kuti aliyense athe kupereka mankhwala, koma ndili ndi milandu yachipatala pomwe palibe china koma cholestyramine yathandizira odwala. Nthawi zonse ndimakumbutsa odwala anga kuti mankhwalawa ali ndi zotsatira zoyipa zambiri.

Chifukwa chake, muyenera kuyang'anitsitsa malangizo ndi mankhwala a chipatala, chifukwa ngakhale mankhwala ocheperako amakhala ndi mavuto osangalatsa - kuyambira m'mimba mpaka m'matumbo. "

Pakuwunika kwa odwala, munthu amatha kumva madandaulo okhudzana ndi mtengo wokwera kwambiri wa cholestyramine komanso kuti ndizovuta kupeza, makamaka kwa okalamba, omwe ali kutali ndi zaluso zamakono ndipo amagwiritsidwa ntchito kugula mankhwala mumafakitala wamba, m'malo mowayamula pa intaneti.

Dimitrova K.A., wazaka 69, penshoni, tawuni ya Magdalinovka. “Ndakhala ndikuvutika ndi cholesterol yayikulu kwa zaka pafupifupi khumi ndi zisanu, kapena kupitirira apo. Chilichonse chomwe adayesera, chikuwoneka ngati chothandiza, koma palibe chomwe chidachitika kwina kulikonse.

Masabata awiri a cholesterol abwinobwino, kenako kamodzi, ndipo adapitanso padenga. Tsopano dotolo pachipatala chachigawo amandipatsa cholestyramine ndipo adandipatsa malangizo a momwe ndingatengere. Kudera lathu, sindinkagula kulikonse, mwana wanga wamkazi wandibweretsa kuchokera mumzinda.

Tsopano ndili ndi miyezi isanu ndi umodzi. Ndipo mukudziwa, ndimakhala wathanzi ndi izi kuposa momwe ndidamwa kale. Ndakhala ndamwa mankhwala a cholestyramine kwa miyezi iwiri tsopano, madokotala amati mayeso anga ndi okhazikika, koma ndi ovomerezeka.

Inde, ndakalamba, ndipo zonse sizingakhaleko, koma ndikumva bwino. ”

Chifukwa chake, malinga ndi malangizo, mankhwalawa Cholestyramine ndi ion-exchange resin, amene amathandiza kwambiri pazovuta zingapo zamankhwala.

Cholestyramine imakhala ndi ndemanga zabwino kuchokera kwa madokotala komanso odwala, komabe, zimatha kuyambitsa zovuta zambiri, ndizodula kwambiri ndipo sizipezeka pama shelufu m'mafamu onse.

Mutha kumwa mankhwalawa pokhapokha mutakumana ndi katswiri, ndikutsatira mosamalitsa malangizo ake onse.

Mankhwala cholestyramine: kumasulidwa mawonekedwe, ndemanga ndi fanizo la mankhwala

Cholestyramine ndi mankhwala a hypocholesterolemic, omwe amayimilidwa ndi resin ya ion-exchange yomwe imamanga asidi a m'matumbo a m'mimba. Mankhwalawa amagwira ntchito ngati Copolymer (mtundu wa ma polima wokhala ndi zigawo zosiyanasiyana) za styrene ndi divinylbenzene.

Mankhwalawa amagwiritsidwa ntchito pofuna kukonza mkhalidwe wa odwala omwe ali ndi cholesterol yayikulu mthupi komanso kuwonongeka kwa bile acid. Mankhwalawa amalekeredwa bwino ndi odwala, kawirikawiri samatsogolera pakukula kwa zoyipa.

Cholestyramine sichifotokozedwa kawirikawiri ngati mankhwala amakono. Nthawi zambiri, odwala amaphunzira za mankhwalawa pophunzira ndemanga za anthu ena. Mwina izi zikuchitika chifukwa cha kukwera mtengo kwa mankhwalawo. Mtengo ndi ma ruble a 1800-2000, phukusi lili ndi mapiritsi 12 a 4000 mg.

Mutha kugula mankhwala pa intaneti kokha, koma osagulitsidwa, chifukwa zinthu zomwe sizinalembetsedwe ku Russian Federation. Ganizirani malangizo omwe mungagwiritse ntchito, contraindication ndi fanizo la cholestyramine.

Pharmacological zochita ndi zikuonetsa ntchito

Mankhwalawa amalimbikitsa kumangiriza kwa ma asidi a bile m'mimba, chifukwa chotsatira chomwe mapangidwe osakira a chelate amapangidwa omwe amachotsedwa m'thupi la munthu m'njira zachilengedwe - limodzi ndi ndowe.

Mankhwalawa amathandizira kuchepetsa kuyamwa kwa cholesterol ndi ma lipid acid ena, amathandizira kupanga mapangidwe a bile acid mu chiwindi (mu mankhwala, mankhwala achire amatchedwa "ndemanga").

Mankhwala onse omwe ali ndi chophatikizira ichi amayang'ana kwambiri kuchepetsa kutsika kwa cholesterol.

Poyerekeza ndi kuzungulira kwa enterohepatic, zoposa 97% za ma asidi a bile zimabwezeretsedwanso m'matumbo, ndiye kuti amalowa m'chiwindi ndikuchotsedwanso limodzi ndi bile.

Chifukwa chake, chiwindi chimangokakamizidwa kuti "achotse" cholesterol kuti apange kuchuluka kwina kwa asidi a bile.

Malangizo ogwiritsira ntchito amalimbikitsa kugwiritsa ntchito mankhwalawa pazinthu zotsatirazi:

Hyperlipoproteinemia yamtundu wachiwiri, makamaka wachiwiri "a",
Kupewa kwa kusintha kwa atherosulinotic ndi matenda monga angina pectoris, infarction ya myocardial, matenda a mtima. Dokotala amatha kukupatsani mankhwala ngati njira zina sizinapatsidwe mankhwala,
Kupuma kwa kuyimitsidwa kwina kosayang'ana kumbuyo kwa kutsekeka kwamtundu wa biliary.

Mankhwala opangidwa ndi Cholestyramine samalimbikitsidwanso kuti azikhala ndi vuto lililonse.

Mitu ya mankhwalawa

Mankhwala ofanana ndi awa ndi monga Studran, Colestir, Ipokol, Cholestan, Colestyramine, ndi mankhwala ena. Cholestan si mankhwala, koma zakudya zowonjezera, zomwe zimapangitsa rutin ndi allicin. Muli akupanga kuchokera ku masamba a artichoke, mababu a adyo, glycine, turmeric muzu wochotsa ndi zinthu zina.

Cholestan ali ndi contraindication: hypersensitivity kwa mankhwala, nthawi ya pakati ndi yoyamwitsa, kapamba kapenanso biliary. Musanagwiritse ntchito, ndikulimbikitsidwa kukaonana ndi dokotala kuti mugwirizane ndi mankhwala ena.

Akuluakulu amatenga mapiritsi 5 kapena makapisozi awiri patsiku ndi zakudya. Njira ya mankhwalawa imachokera ku milungu itatu mpaka isanu ndi umodzi. Ndemanga za odwala ndizabwino, malingaliro a madokotala sawonetsedwa.

The fanizo la achire zotsatira zimaphatikizapo mankhwala kuchokera gulu la statins:

Atorvastatin
Lovastatin,
Simvastatin
Pravastatin et al.

Kapangidwe kamankhwala kamayimiriridwa ndi magawo omwe amagwira ntchito omwe amatha kuchepetsa kuchuluka kwa cholesterol "yoyipa". Mlingo umakhazikitsidwa kutengera ndi zaka, poganizira zotsatira za mayeso.

Cholestyramine ndi mankhwala a hypocholesterolemic, koma pakadali pano madokotala sawalemba, popeza mankhwalawa sanalembetsedwe mwalamulo. Chifukwa chake, kuti muchepetse magazi m'magazi, amalimbikitsa kufananiza kwa mankhwala, omwe amaperekedwa m'njira zosiyanasiyana.

Zambiri pa cholesterol zimaperekedwa mu kanema munkhaniyi.

Sonyezani shuga yanu kapena sankhani jenda kuti muyimikize.

Malangizo ogwiritsira ntchito kuti mupeze kuti mankhwalawa amalekeredwa bwino, chifukwa samachokera m'matumbo ndipo samakhudza kugwira ntchito kwa ziwalo zina ndi machitidwe ena. Koma zimadziwika ndi odwala makamaka kuchokera kwa odwala ena omwe adalandira mankhwalawa.

Inde, tsopano "Cholestyramine" sigwiritsidwa ntchito konse ngati mankhwala ku Russia. Chifukwa chake, musanagwiritse ntchito mankhwalawa, muyenera kufunsa dokotala.

Ndemanga pa ntchito ya "Cholestyramine"

Malangizo ogwiritsira ntchito, ndemanga zokhudzana ndi mankhwalawa komanso zotsatira zake zoyipa zimakhala pamavuto ambiri. Odwala omwe amathandizidwa ndi wothandizirawa, akuwonetsetsa kuti zinthu zikuyenda bwino komanso kuti palibe mavuto omwe amayambitsidwa.

Mankhwalawa amalekeredwa bwino, amasintha kagayidwe ndipo amakonza magwiridwe antchito a chiwindi ndi ndulu.