Formetin kapena Metformin

Fomu ndi Metformin ali m'gulu lomwelo la zamankhwala ndi zamankhwala "othandizira a Hypoglycemic", gululi - Biguanides ogwiritsira ntchito mkati. The achire zotsatira za mankhwala amatengera zimatha metformin - waukulu yogwira mankhwala.

Kuti mudziwe kusiyana pakati pa Fomu ndi Metformin ndipo ndilabwino, ndikofunikira kuyerekezera mankhwalawa malinga ndi njira zosiyanasiyana.

Mitundu ndi kapangidwe kake

Kuti mufananitse mankhwala, mawonekedwe akuluakulu amitundu yonse yamankhwala amawaganizira.

Wopanga ndi kampani ya ku Russia yotchedwa Pharmstandard Tomskkhimfarm.

Mankhwalawa amasulidwa ngati mapiritsi.

Pali mitundu iwiri:

• Fomu,
• Formethine Long - Kumasulidwa Kutulutsidwa.

Chosakaniza chophatikizacho ndi metformin hydrochloride.

Zinthu zazing'ono:

• povidone
• magnesium wakuba,
• Hyprolose
• lactose monohydrate,
• primellose,
• silika.

Opanga Makulidwe:

• Makampani opanga ku Russia - Biochemist, Canonpharma Production, Izvarino Pharma, Vertex, Rafarma, Atoll, Biosynthesis, Medisorb,
• Hemofarm, Serbia,
• Zentiva, Slovakia,
• Chomera cha Borisov chokonzekera zamankhwala, Belarus,
• Teva, Israeli
• A George Richter, aku Hungary.

Kutulutsa mawonekedwe - mapiritsi.

Mitundu:

• Metformin.
• Metformin Zentiva.
• Kutalika, MV-Teva - kuchitapo kanthu kwa nthawi yayitali.
• Long Canon, MV - kumasulidwa kosasunthika.
• MS.
• Richter
• Teva.

Chofunikira kwambiri ndi metformin hydrochloride.

Zigawo zing'onozing'ono zopezeka m'njira zosiyanasiyana zamankhwala:

• povidone
• glyceryl
• Mg wakuba
• Hyprolose
• crospovidone
• lactose monohydrate,
• kukhuthala
• calcium owawa
• silicon dioxide
• cellulose
• sodium croscarmellose,
• talcum ufa
• hypopellose,
• prosv.

Kuyerekeza kwa Metformin ndi Formmetin ndi opanga kukuwonetsa kuti Metformin imapangidwa ndi makampani osiyanasiyana opanga mankhwala - kuchokera kunyumba mpaka opanga odziwika padziko lonse lapansi, ndipo Fomati limapangidwa ndi kampani yaku Russia.

Mitundu ya kumasulidwa kwa mankhwalawa ndiofanana - mapiritsi ndi mtundu wa mapiritsi a nthawi yayitali.

Zomwe zimachitika popanga Metformin ndi Formetin zimabwerezedwa.

Kusankhidwa

Mankhwala Metformin ndi Formmetin amawonetsedwa chifukwa chodwala matenda a shuga osadalira insulin, makamaka kwa odwala omwe ali onenepa kwambiri komanso ngati kudya ndi kuchita masewera olimbitsa thupi sizothandiza. Zithandizo zimayambitsa kuchepa thupi.

Mankhwala angagwiritsidwe ntchito onse mu mawonekedwe a monotherapy, ndiko kuti - palokha, komanso movutikira - kuphatikiza othandizira ena achi hypoglycemic omwe amagwiritsidwa ntchito mkati, komanso jakisoni wa insulin.

Contraindication

The achire zotsatira ndi chitetezo cha mankhwala zimatengera kukhalapo kwa contraindication. Popeza onse Metformin ndi Formmetin ali mgulu lamankhwala amodzi, ali ndi zinthu zomwezo ndipo ali ndi fanizo, ali ndi zotsutsana zomwezo.

Mndandanda wa ziletso zazikulu:

• wodwala matenda ashuga
• lactic acidosis
• metformin tsankho,
• kulephera kwa aimpso
• ketoacidosis
• uchidakwa wambiri,
• vuto la mtima
• matenda oopsa
• kulephera kupuma
• kusowa kwamadzi
• acidosis
• chiwindi ntchito,
• kulephera kwa mtima
• kuyambitsa kwa zinthu zophatikizana ndi ayodini.

Ponena za kugwiritsa ntchito mankhwala pa nthawi ya pakati, Foromu ndi mitundu ina ya Metformin (Teva, Richter, Zentiva), malinga ndi malangizo, amatsutsana kwathunthu panthawiyi. Mtundu wautali ndi mitundu ina ya Metformin sioyenera kugwiritsidwa ntchito ndi amayi oyembekezera pokhapokha ngati kuli koyenera komanso chilolezo cha adokotala.

Mankhwala salimbikitsidwa kwa amayi oyamwitsa, komanso kwa odwala azaka zopitilira 60 omwe achita ntchito yayikulu.

Kugwiritsa

M'pofunika kumwa mankhwala mosamalitsa ndi malangizo a mankhwalawa, mukumvera malangizo ndi malangizo a dokotala.

Malinga ndi kufotokozeredwa kwa yankho, tikulimbikitsidwa kumwa mapiritsi mukamadya chakudya kapena mukangodya. Mlingo wake umasankhidwa payekha, kutengera mtundu womwe umagwiritsidwa ntchito, poganizira msinkhu wa wodwalayo.

Kodi mankhwalawa amafanana bwanji?

Mfundo zodziwika bwino ndi izi:

• Njira yomweyo yotulutsira ndi kumwa.
• Chizindikiro chogwira ntchito.
• Zofanana zoyipa zimachitika, contraindication.
• Ntchito mtundu 2 shuga, kunenepa kwambiri.
• Mtengo wovomerezeka.
• Thandizo labwino.

Kufanana kumeneku kumapangitsa kuti zikhale zovuta kusankha pakati pa mankhwala awiri.

Kodi pali kusiyana kotani pakati pa mankhwala?

1. Imaperekedwa ndi makampani osiyanasiyana, mayiko.
2. Amasiyana mu kapangidwe ka ochulukitsa.
3. Metformin imawononga ndalama zochulukirapo.
4. Metformin, malinga ndi odwala ndi madokotala, sangakhale ndi vuto lalikulu.

Kodi ndi bwino kusankha?

Mankhwalawa amapangidwa chifukwa cha chinthu chimodzi chogwira ntchito, amakhala ndi chinthu chimodzi chogwirira ntchito ndikuwonetsa. Chifukwa chake, ndizovuta kwambiri kuyankha funsoli, lomwe ndilabwino, Formmetin kapena Metformin. Apa ndikofunikira kuti muchoke kuchokera pazachuma komanso kusinthika kwa zinthu zothandizira.

Ngati mukufuna kupulumutsa ndalama pamankhwala, ndiye kuti muyenera kusankha Forethine. Ngati mukufuna kugula mankhwala abwinoko, ndiye kuti muyenera kugula Metformin yoitanitsidwa kunja. Monga lamulo, limavomerezedwa bwino ndi thupi.

Makhalidwe a Metformin

Ichi ndi mankhwala a hypoglycemic, mawonekedwe ake omwe mapiritsi ndi matulutsidwe. Chosakaniza chophatikizacho ndi metformin, ndipo zina zowonjezera ndi talc, magnesium stearate, ndi wowuma. Mankhwalawa amachepetsa mapangidwe a glucose m'thupi ndikuthamanga kupasuka kwake. Ndi matenda a shuga, kuchuluka kwamafuta acids kumachulukitsa, zomwe zimapangitsa kuti thupi lizikula, ndipo mankhwalawa amalepheretsa mapangidwe awo.

Kuphatikiza apo, kunenepa kumachitika chifukwa cha insulin, yomwe imasungidwa nthawi zonse pamlingo waukulu, ndipo Metformin imatsitsa. Izi ndizofunikira popewa zovuta za mtima komanso kuwonda. Mankhwala amalowetsa magazi bwino, salola makoma amitsempha yamagazi kuti achepetse, amachepetsa kuchuluka kwamafuta oyipa, ndikuwonjezera kuchuluka kwa lipoproteins yapamwamba. Mankhwala amachepetsa kuyambika kwa matenda ashuga angiopathy.

Mankhwalawa akuwonetsedwa kuti azigwiritsidwa ntchito mu mtundu 2 wa matenda ashuga omwe amalephera kudya:

• mwa akulu - monga njira yokhayo kapena molumikizana ndi mankhwala ena a hypoglycemic,
• mwa ana azaka zapakati pa 10 ndi akulu - omwe ali ndi insulin kapena ngati chida chokha.

• matenda ashuga ketoacidosis, precoma ndi chikomokere,
• chiwindi ndi impso ntchito.
• opaleshoni ndi kuvulala (pa mankhwala a insulin),
• lactic acidosis,
• kutsatira zakudya zochepa zopatsa mphamvu,
• zakumwa zoledzeretsa kwambiri, uchidakwa wambiri,
• tsankho pamagawo a mankhwala,
• mimba
• nthawi yoyamwitsa,
• zilonda zapakhosi, zomwe zimayendera limodzi ndi chiwopsezo chaimpso ntchito: kuchepa kwamadzi, kutentha thupi, matenda a impso, matenda am'mapapo, kugwedezeka, sepsis,
• kupuma kapena kulephera kwa mtima, kulowetsedwa kwa myocardial.

Metformin contraindication: diabetesic ketoacidosis, pachimake ndi chikomokere, matenda a chiwindi ndi impso.

Mankhwalawa amaletsedwa kumwa pakati pa masiku awiri isanachitike komanso pambuyo pa kuyeserera kwa radioisotope kapena X-ray, momwe adagwiritsa ntchito iodine wogwirizira. Sitikulimbikitsidwa kugwiritsa ntchito mankhwalawa kwa odwala omwe ali ndi zaka zopitilira 60, chifukwa amatha kupangitsa kukhazikitsa lactic acidosis.

Nthawi zina kumwa mankhwalawa kumayambitsa zotsatirazi, monga:

• kusanza, kusanza,
• kulawa kwazitsulo mkamwa
• kuchepa kwamtima
• chisangalalo
• kupweteka m'mimba
• kukula kwa hypoglycemic zimachitika,
• anemia yam'magazi,
• zotupa pakhungu
• lactic acidosis,
• hypovitaminosis B12.

Metformin mu mlingo wa 85 g ungayambitse bongo, zomwe zimakwiyitsa kukula kwa lactic acidosis. Uku ndikuvutikira kowopsa, limodzi ndi mseru, kutsekula m'mimba, kusanza, kupweteka m'mimba, kupweteka kwa minofu, ndi kutentha thupi. Ngati wodwala sanathandizidwe mwachangu munthawi yake, chizungulire chimatha, amapumira mofulumira, amakhala ndi chikumbumtima chododometsa.

Kugwiritsa ntchito Metformin sikumapangitsa hypoglycemia, koma chisamaliro chimayenera kutengedwa kuphatikiza ndi insulin ndi sulfonylurea. Zinthu zina zimachepetsa kuthamanga kwa mankhwalawa ndikupangitsa chithandizo kukhala chothandiza: adrenaline, glycogen, mahomoni a chithokomiro, etc.

Kuphatikiza kwa mankhwalawo ndi mankhwala okhala ndi ayodini kumapangitsa kuti pakhale lactic acidosis. Odwala omwe amamwa chlorpromazine ayenera kuwonjezera kuchuluka kwa Metformin, chifukwa mankhwala oyamba mu Mlingo waukulu umatseka kupanga insulin.

Kuchita kwa Forethine

Ichi ndi cholumikizira cha hypoglycemic, mtundu wake womwe mapiritsi ndi mapiritsi. Kuphatikizika kwa mankhwalawa kumaphatikizapo gawo lalikulu - metformin hydrochloride.

Formetin imathandizira kugwiritsidwa ntchito kwa shuga, imachepetsa kulemera.

Mankhwalawa ali ndi izi:

• imathandizira kugwiritsidwa ntchito kwa shuga,
• amateteza kulemera
• zimawonjezera chidwi cha minofu pazovuta za insulin,
• Imachepetsa kupangika kwa shuga m'magazi.

Mankhwala sayambitsa extraneous hypoglycemic reaction. Mankhwalawa amachotseredwa limodzi ndi mkodzo, amadziunjikira m'chiwindi, impso ndi minofu.

Zisonyezero ntchito: lembani matenda a shuga a 2 odwala akulu ndi ana opitilira zaka 10 pang'onopang'ono chifukwa cha zovuta kuchita pakudya.

• pachimake kapena matenda acidosis, matenda a shuga ndi chikomokero, ketoacidosis,
• hypoglycemic shock, kuchepa magazi, komwe kumatha kusokoneza kugwira ntchito kwa impso,
• kuwonongeka kwaimpso,
• kulephera kwa aimpso
• Hypersensitivity pamagawo a mankhwala,
• uchidakwa wambiri, kuledzera
• kugwiritsa ntchito mankhwala osiyanitsa ndi ayodini chifukwa opaka misempha.

Ngati kuli kofunikira, formin imatengedwa panthawi yomwe muli ndi pakati, ndipo sikulimbikitsidwa kuti mugwiritse ntchito yoyamwitsa. Ndi zoletsedwa kumwa mankhwalawa kwa odwala azaka zopitilira 60, chifukwa chiopsezo chokhala ndi lactic acidosis chikuwonjezeka.

• kusanza, kusanza, kusasangalala pamimba, kusefukira kwam'mimba, kutsegula m'mimba,
• kawirikawiri - lactic acidosis,
• chosowa kwambiri - malabsorption a vitamini B12,
• kuchepa magazi kwa megaoblastic, komwe kumayendetsedwa ndi kuzizira, miyendo, kupindika, kufooka kwapafupipafupi, kukhumudwa,
• kutopa, kuda nkhawa, kukokana, kuyerekezera zinthu zina,
• achina,
• zotupa pakhungu.

Kuchita kwa mankhwala osokoneza bongo a Formetin: ndizoletsedwa kuphatikiza ndimankhwala monga anticoagulants, kulera kwapakamwa, thiazide-mtundu diuretics, cimetidine, chlorpromazine, danazole, MAO ndi zoletsa ACE.

Kuyerekeza kwa Metformin ndi Fomu

Kuti mudziwe mankhwala omwe ndi othandiza kwambiri, muyenera kudziwa zomwe zimakonda pakati pawo, komanso momwe zimasiyana.

Metformin ndi formin amafanana:

• yemweyo yogwira pophika ndi kumasulidwa mawonekedwe,
• Zizindikiro zomwezo
• Mlingo wofanana
• angagwiritsidwe ntchito mankhwala a insulin,
• okhala ndi zotsutsana zofanana
• mutha kugula kokha ndi mankhwala.

Ma Analogs a Metformin

• Bagomet,
• Glycon
• Glyminfor,
• Glyformin
• Chikwanje,
• Glucophage Long,
• Langerine
• Methadiene
• Metospanin
• Metfogamma 1000,
• Metfogamma 500,
• Metfogamma 850,
• Metformin
• Metformin Richter,
• Metformin Teva,
• Metformin hydrochloride,
• Nova Met
• NovoFormin,
• Siofor 1000,
• Siofor 500,
• Siofor 850,
• Sofamet
• Fomu,
• Forin Pliva.

Zizindikiro za matenda ashuga - kanema

Kuyerekeza kwa Metformin ndi Fomu

Metformin ndi formin si mankhwala omwewo. Kuti mudziwe njira yabwino, ndikofunikira kufananiza mankhwala ndikuwona kusiyana kwawo, kufanana kwawo.

Sizikupanga nzeru kusankha mankhwala omwe ali bwino kutengera mawonekedwe ake. Mankhwala onse awiriwa ali ndi chinthu chimodzi chomwe chikugwiritsidwa ntchito pakuphatikizika ndi zisonyezo zogwiritsidwa ntchito.

Metformin ndi formin amatengedwa Mlingo wofanana.

Mapiritsi sayenera kutafuna. Amadyedwa yonse ndikutsukidwa ndimadzi ambiri. Izi zimachitika bwino mukamadya kapena mukatha kudya. Kuchuluka kwa madyerero patsiku kumatengera kuuma kwa mkhalidwe wa wodwalayo.

Kumayambiriro kwa mankhwalawa, 1000-1500 mg patsiku amalembedwa, ndikugawa kuchuluka kwa 3 waukulu. Pambuyo pa masabata 1-2, mlingo umatha kusintha malingana ndi kuchuluka kwa zinthu zomwe zimafunikira kuti magawo azikhala ndi kuchuluka kwa shuga.

Mutha kusinthira ku Metformin kapena Formmetin kuchokera kuma analogi ena patsiku limodzi lokha, popeza kuchepetsa mlingo sikufunika.

Ngati mulingo wonjezeredwa pang'onopang'ono, ndiye kuti kulekerera kwa mankhwalawo kudzakulirakulira, popeza mwayi wazotsatira zoyambira m'mimba zimachepa. Mlingo wofanana patsiku ndi 2000 mg, koma oposa 3000 mg ndi oletsedwa.

Mutha kusinthira ku Metformin kapena Formmetin kuchokera kuma analogi ena patsiku limodzi lokha, popeza kuchepetsa mlingo sikufunika. Koma onetsetsani kuti mwadya moyenera.

Mankhwala amatha kumwedwa panthawi ya insulin.

Pankhaniyi, mlingo woyamba ukhale 500-850 mg patsiku. Gawani chilichonse katatu. Mlingo wa insulin amasankhidwa pamalangizo a madokotala kutengera zotsatira za kuyezetsa magazi.

Kwa ana, onse mankhwala amaloledwa kuchokera zaka 10. Poyamba, mlingo ndi 500 mg patsiku. Mutha kumwa kamodzi patsiku ndi chakudya madzulo. Pambuyo pa masabata awiri, mlingo umasintha.

Popeza Metformin ndi Formmetin ali ndi zomwe zimapangidwanso, zomwe zimabweretsa ndizofanana. Dzuka:

• mavuto ndi chakudya cham'mimba, chomwe chimaphatikizidwa ndi kupweteka kwam'mimba, kutsegula m'mimba, kusanza, kusanza, kutsekemera kwazitsulo mkamwa, bata,
• kusowa kwa vitamini, makamaka B12 (mogwirizana ndi izi, odwala amathandizanso kukonzekera mavitamini),
• thupi lawo siligwirizana ndi zigawo zikuluzikulu za mankhwalawa (zoonekera pakhungu, pakhungu, kuyabwa, kuwawa),
• kuchepa magazi
• lactic acidosis,
• kutsitsa shuga m'magazi m'munsi mwabwinobwino.

Contraindication a Metformin ndi Formetin ndi awa:

• aakulu ndi pachimake metabolic acidosis,
• glycemic coma kapena mkhalidwe patsogolo pake,
• Kusokonezeka kwa chiwindi,
• kusowa kwamadzi,
• kuphwanya impso ntchito,
• kulephera kwamtima komanso kulowerera m'mitsempha,
• matenda opatsirana
• mavuto kupuma
• uchidakwa.

Kwa ana, onse mankhwala amaloledwa kuchokera zaka 10.

Mankhwalawa onse ndi oletsedwa kugwiritsa ntchito musanachite opareshoni. M'pofunika kudikirira masiku 2 musanachitike opareshoni.

Zomwe zimakhala zotsika mtengo

Mwa mankhwala onsewa, opanga ndi makampani monga Canon, Richter, Teva, ndi Ozone.

Mlingo wa mankhwala ophatikizira piritsi limodzi ndi 500, 850 ndi 1000 mg uliwonse. Pamtengo, onse a Metformin ndi Formmetin ali mgulu lofanana: woyamba ungagulidwe ku Russia pamtengo wa pafupifupi ruble 105 kwa phukusi la mapiritsi 60, ndipo kwa chachiwiri, mtengo wake uzikhala pafupifupi ma ruble 95.

Zolemba Zosintha Zosankha za Fomuine

Choyamba, ndikofunikira kuzindikira kuti Forthine sanapangidwe poyambirira kuti athetse thupi lolemera. Koma amachepetsa kwambiri njira yobwera ndi chakudya chamafuta. Nthawi zambiri mankhwalawa amagwira ntchito pama carbohydrate othamanga. Zotsatira zake, kuchuluka kwa shuga kumachepa, ndipo zochitika za pancreatic zimabwereranso.Koma chifukwa chiyani zonsezi zimagwirizanitsidwa ndi kuchepa thupi? M'malo mwake, kulumikizana ndikulunjika.

Mothandizidwa ndi Formetin, mutha kupanga zinthu zomwe zimapangitsa kuti kuchepetsa thupi kuzikhala kosavuta komanso kosavuta. Ngakhale muyenera kutsatira zina zowonjezera. Kuti muchepetse kunenepa mukamamwa mapiritsi otere, muyenera kuganizira izi:

• Siyani kugwiritsa ntchito zakudya zokhala ndi shuga,
• chakudya chilichonse ayenera kuchepetsedwa
• Kuti muchepetse kuchepa thupi, muyenera kudzipatsa zolimbitsa thupi.
• Pambuyo masiku 20 motsatana, ayenera kupuma kwa mwezi umodzi.

Chifukwa chake, Forethine alibe chozizwitsa china chilichonse. Ndipo lonjezo loti "athetsa mafuta" ndiwongochenjera chabe. Koma, komabe, ndizotheka kukwaniritsa kuchepetsa thupi pogwiritsa ntchito. Ndipo ndemanga zomwe zimaperekedwa pa Formetin kuti muchepetse thupi zimangotsimikizira izi. Zikuwonekerabe kuti tanthauzo la kugwiritsa ntchito mapiritsiwo ndi liti kwenikweni. Kenako zotsatira zakuvomera kwawo ndizabwino kwambiri.

Limagwirira ntchito ya Metformin

Glucophage - amatchedwanso metformin hydrochloride, piritsi lomwe limapangidwa kuti likhale ndi akulu akulu odwala matenda ashuga a mtundu 2. Mankhwala amatha kuthetsa shuga mu chiwindi ndikuchepetsa kuyamwa kwa glucose m'matumbo. Komabe, ngati mulibe insulin m'magazi a anthu, metformin sapereka zotsatira.

Kuchokera pazomwe tafotokozazi, funso limabuka: chifukwa chiyani anthu amasankha mapiritsi awa kuti achepetse thupi? Ndipo chinthu apa ndikuti mankhwalawa amalepheretsa kupangika kwamafuta mthupi lathu. Komanso, mafuta amasinthidwa kukhala mphamvu. Ndi chifukwa chake othamanga ambiri amagwiritsa ntchito glucophage kuti achepetse thupi.

Magwiridwe a mapiritsi ndi awa:

• Imachepetsa mayamwidwe am'mimba m'matumbo,
• amalimbikitsa kukhatikiza kwamphamvu kwa mafuta acids,
• Amathandiza kuchepetsa thupi komanso kukhazikika pamtunda,
• bwino minyewa yodwala,
• amachepetsa kupanga insulin
• nkhondo yolimba.

Munthu aliyense amene anaganiza zochepetsa thupi mothandizidwa ndi metformin ayenera kumvetsetsa bwino mfundo imodzi: mankhwalawa si panacea yowonjezera kulemera. Metformin siziwotcha mafuta, zimangothandiza kuonetsetsa kuti thupi lathu limagwiritsa ntchito ma deposits amafuta, osati minofu ya minofu. Choyambirira cha ichi ndichakudya choyenera.

Kutenga metformin, muyenera kusiya zakudya zamafuta othamanga (shuga, maswiti, nthochi, ndi zina), komanso mpunga woyera, mbatata, pasitala, "zipatso" zothamanga "m'matumba. Pazakudya za tsiku ndi tsiku, ngati simudzipatsa nokha masewera olimbitsa thupi, pazikhala zosaposa 1199 kcal.

Iwo ali osavomerezeka kuti apereke mankhwala kwa odwala:

• ndi vuto la impso ndi chiwindi,
• ndi matenda ashuga a ketoacidosis,
• ngati akudwala matenda ashuga komanso okoma.
• ndi matenda opatsirana nthawi yayitali kapena pachimake, omwe angayambitse kusokonekera kwa impso (hypoxia, kuchepa madzi m'thupi, sepsis, malungo, matenda a impso, kugwedezeka) kapena kutsogolera kwa minofu hypoxia (myocardial infarction, kupuma, komanso kulephera kwa mtima),
• Mankhwala a insulin chifukwa cha opareshoni kapena kuvulala kwambiri,
• ndi uchidakwa woperewera kapena pambuyo poyamwa poizoni,
• ndi chidwi chachikulu,
• pa mimba ndi kuyamwa,
• ndi acidosis,
• ndi chakudya chama hypocaloric.

Kuphatikiza apo, simuyenera kugwiritsa ntchito mawonekedwe a Formetin 2 m'mbuyomu komanso pambuyo pa maphunziro a x-ray ndi radioisotope, pomwe ma reagents okhala ndi ayodini amagwiritsidwa ntchito ngati njira yosiyanitsa.

Sitikulimbikitsidwanso kugwiritsa ntchito mankhwalawa pochiza odwala omwe ali ndi zaka zopitilira 60 omwe amagwira ntchito yayikulu, kuti apewe kukula kwa lactic acidosis mwa iwo.

Zotsatira Zogwiritsa Ntchito Mankhwala

Formmetin ndi mankhwala apadziko lonse: angagwiritsidwe ntchito monotherapy kapena kuphatikizidwa ndi mankhwala ena a hypoglycemic, kuphatikiza jakisoni wa insulin.

Koma nthawi zina, pochiza matenda othandizira, kuchira kwovuta kumatha kukhala ndi zotsatirapo zoyipa.

1. Ndi makonzedwe omwewo a Danazol, pali chiopsezo cha zotsatira za hypoglycemic, kotero mlingo wa mankhwalawo uyenera kuyang'aniridwa mosamalitsa kapena kusinthanitsa ndi analog.
2. Akaphatikizidwa ndi cimetidine, mawonekedwe a metformin amalephereka, kuchuluka kwake mthupi kumatha kupereka mphamvu yosagwirizana ndi hypoglycemic.
3. Kutha kwa coumarin kumachokera ku ziletsa metformin.
4. Mankhwala osakanikirana ndi carbazole, NSAIDs, clofibrate, insulin, ACE inhibitors, cytophosphamide, β-blockers, sulfonylureas, oxytetracycline amathandizira ntchito ya metformin.
5. Kuphatikiza komweko kwa glucagon, epinephrine, thiazide diuretics, mahomoni a chithokomiro amalepheretsa kugwira ntchito kwa formin.

Pogwiritsa ntchito njira zakulera zamkamwa, mayi ayenera kuuza mitundu ya mankhwalawo kwa endocrinologist kuti asinthe mlingo wa Formetin. Osam'patsa mankhwala komanso kuphatikiza ndi Nifedipine, womwe umakulitsa kuchuluka kwa metformin m'magazi, imathandizira kuyamwa kwake, imachepetsa kuchoka. Ngati pali vuto ndi impso, zotsatira zake zingayambitse kukomoka.

Ngati mankhwalawa adakhazikitsidwa ndi ethanol, kuphatikiza ndi metformin, chiopsezo cha lactic acidosis chimawonjezeka kwambiri.

Formethine si vuto lotchedwa panacea, ngati mankhwala aliwonse osokoneza bongo, koma ngati zonse zofunika zikutsatiridwa, zimathandiza kuwongolera matenda ashuga kwa nthawi yayitali, osalimbikitsa thupi, monga mawonekedwe ake.

Mankhwala osokoneza bongo a "Fomu" amawonetsedwa pamene amatenga 0,85 magalamu patsiku ndikuyambitsa lactic acidosis. Komanso, zomwe zili zapamwamba kwambiri za metformin zimachitika chifukwa chosagwira bwino impso.

Zizindikiro zoyambirira za lactic acidosis ndi kufooka kwa thupi lonse, kumatulutsa, kuchepetsa kutentha kwa thupi, kupweteka m'mimba ndi minofu, kutsitsa magazi, Reflex bradyarrhythmia. Nthawi zina, mumakhala mukuwonetsa kupuma pafupipafupi, kusokonezeka kwa chikumbumtima, chizungulire, ndipo zotsatira zake, mumatha kupuma.

Pakangoyamba kumene chizindikiro cha bongo, ndikofunikira kusiya kugwiritsa ntchito mankhwalawo ndikuyang'ana kwa dokotala kuti mutsimikizire matenda a lactic acidosis. Kuchotsa zomwe zimagwiritsidwa ntchito popanga mankhwalawa ndi lactic acid mthupi, hemodialysis yofanana ndi chithandizo chamankhwala ingathandize.

Makampani ogulitsa mankhwala amapanga mankhwala omwe ali ofanana ndikupanga ndi mawonekedwe a formin. The fanizo la mankhwala ndi:

• Bagomet. Mankhwalawa ndi piritsi ya nthawi yayitali, chinthu chomwe chimagwira ndi metformin. Bagomet imakhala ndi hypoglycemic effect, kugwiritsidwa ntchito kwake kumathandizira kukhazikika kapena kuchepetsa thupi. Amagwiritsidwa ntchito mu zovuta za matenda a shuga a insulin.
• Glucophage. Zomwe zimagwiritsidwa ntchito ndi metformin hydrochloride. Glucophage imamasulidwa mu mawonekedwe am'mapiritsi a pakamwa. Mankhwalawa amathandiza kutsitsa shuga m'magazi popanda kuchititsa hypoglycemia. Poyerekeza ndi kagwiritsidwe ntchito ka odwala, kuchepa thupi kumachitika. Glucophage amalembedwa mtundu wa matenda ashuga 2.
• Glformin. Mankhwalawa ali ndi vuto la hypoglycemic. Mankhwala piritsi. Amasankha mtundu 1 komanso mtundu wa matenda ashuga 2. Kugwiritsidwa ntchito kwake kumathandiza odwala omwe ali ndi matendawa kuti azisamalira kapena kuchepetsa thupi.
• Metformin. Mapiritsi ndi a Biguanides, amathandizira kuletsa kayendedwe ka gluconeogenesis m'chiwindi, kuchepetsa kuyamwa kwa glucose, kumathandizira kugwiritsidwa ntchito kwake. Kutumiza, mogwirizana ndi malangizo, kusintha kulemera kwa odwala omwe ali ndi matenda amtundu wa 2 komanso a 2.
• Siofor. Hypoglycemic mankhwala opangidwa piritsi. Mankhwala ali antidiabetes, tingati kuyamwa kwa shuga, kumawonjezera mphamvu ya zotumphukira zimakhala kuti insulin. Kugwiritsa ntchito kwa Siofor kumathandizira pakumanga kwa lipid, njira yozizira. Malinga ndi malangizo, amamulembera mtundu wachiwiri wa matenda osokoneza bongo, ngati wodwalayo atopa kunenepa kwambiri.
• Metformin hydrochloride. Mafuta osungunuka a crystalline. Mankhwala amachepetsa kupanga shuga ndi chiwindi, amachepetsa mayamwidwe m'mimba, amachepetsa kaphatikizidwe ka glycogen, amakhudza kagayidwe ka lipids, kuchepetsa kuchuluka kwa cholesterol, lipoproteins, triglycerides. Kugwiritsa ntchito kwanyengoyi kumathandizira kuchepetsa kapena kukhazikika pamenepa. Malinga ndi malangizowo, umagwiritsidwa ntchito ngati matenda a shuga 2 kwa odwala omwe ali ndi kunenepa kwambiri.
• Sofamet. Chidacho chimanena za mankhwala a hypoglycemic omwe cholinga chake ndi pakamwa. Malinga ndi malangizo, Sofamet imatha kupondereza gluconeogenesis, oxidation yamafuta, komanso mapangidwe a mafuta achilengedwe aulere. Pa mankhwala, kuchepa kwapang'onopang'ono kapena kukhazikika kwa kulemera kwa wodwalayo kumachitika. Imafotokozedwa chifukwa chosagwira ntchito kuchokera ku zakudya komanso zolimbitsa thupi kwa odwala omwe ali ndi matenda a shuga a 2.
• Novoformin. Mankhwalawa amagawidwa mu mawonekedwe a mapiritsi. Novoformin ali ndi vuto la hypoglycemic, amachepetsa kuchuluka kwa shuga m'thupi. Kugwiritsa ntchito mankhwalawa kumathandizira kukhazikika kapena kuchepetsa pang'onopang'ono kulemera kwa 2 shuga kwa odwala onenepa kwambiri.

Ali ndi mawonekedwe apiritsi yotulutsidwa. Chofunikira chachikulu pakuphatikizidwapo ndi pawiri wa dzina lomweli. Amapezeka mu Mlingo wa 500 ndi 850 mg.

Metformin ili ndi chinthu chofunikira kwambiri cha dzina lomweli.

Mankhwala ndi a gulu la Biguanides. Kupanga kwamankhwala kumapangidwa ndikuwonetsa kulepheretsa kupanga kwa chiwindi mu chiwindi ndikuchepetsa mayamwidwe ake m'matumbo. Mankhwala samakhudzana ndi kupanga kwa insulin mu kapamba, motero palibe chiopsezo cha hypoglycemic reaction.

Mankhwalawa ali ndi phindu pamtima wamatumbo, amaletsa kukula kwa angiopathy mu shuga.

Mothandizidwa ndi pakamwa pakumwa mankhwala, muyezo waukulu wa yogwira pophika umapezeka m'magazi 2,5. Kuyamwa kwa piritsi kumayima maola 6 mutatha kumwa mapiritsi. Kuchotsa hafu ya moyo wa chinthucho ndi pafupifupi maola 7. Bioavailability wafika 60%. Amathira mkodzo.

Zizindikiro zogwiritsidwa ntchito Metformin - matenda osokoneza bongo a mitundu yoyamba komanso yachiwiri. Mankhwalawa amatchulidwa ngati njira yothandizira insulin mankhwala komanso kugwiritsa ntchito mankhwala ena, popeza kuyanjana kwa mankhwalawa kwawonetsa zotsatira zabwino. Metformin imalembedwanso monga chida chachikulu munthawi yamankhwala.

Mankhwala amalepheretsa kupanga shuga mu chiwindi komanso amachepetsa kuyamwa kwake m'matumbo.

Mankhwalawa sakukhudza momwe amapangira insulin mu kapamba.

Mankhwalawa amagwiritsidwa ntchito ngati kunenepa kwambiri, ngati mukufuna kuwongolera kuchuluka kwa shuga m'magazi, bola ngati zakudya sizipereka zotsatira zabwino. Mankhwala ena amatha kuthandizira kuti apezeke ovomerezeka a polycystic, koma mu nkhani iyi, mankhwalawa amagwiritsidwa ntchito moyang'aniridwa ndi dokotala.

Kodi formetin ndi iti?

Formetin ndi analogue ya mankhwala achijeremani a Glucophage: ili ndi zinthu zomwezo, ili ndi mitundu yofanana ya mapiritsi. Kafukufuku ndi kuwunika kambiri kwa odwala kunatsimikizira kufanana kwa onse a mankhwalawa a shuga. Opanga Formetin ndi gulu la ku Russia la makampani opanga mankhwala a Pharmstandard, omwe tsopano ali ndi udindo waukulu pamsika wamankhwala.

Monga Glucophage, Formetin imapezeka m'mitundu iwiri:

Pakadali pano, metformin imagwiritsidwa ntchito osati pochiza matenda a shuga, komanso matenda ena a pathological omwe amaphatikizidwa ndi insulin.

Madera ena ogwiritsira ntchito mankhwala Fomu:

1. Kupewa matenda a shuga Ku Russia, kugwiritsa ntchito metformin kumaloledwa pachiwopsezo - mwa anthu omwe ali ndi mwayi wambiri wodwala matenda a shuga.
2. Formetin imakupatsani mwayi wolimbikitsira ovulation, chifukwa chake amagwiritsidwa ntchito pokonzekera kutenga pakati. Mankhwalawa amavomerezedwa ndi American Association of Endocrinologists ngati mankhwala a mzere woyamba wa polycystic ovary. Ku Russia, chizindikiro ichi chogwiritsidwa ntchito sichinalembetsedwe, chifukwa chake, sichikuphatikizidwa pamalangizo.
3. Formethine imatha kukonza chiwindi ndi steatosis, yomwe nthawi zambiri imayendera limodzi ndi shuga ndipo ndi amodzi mwa zinthuzi.
4. Kuchepetsa thupi ndi insulin kukana. Malinga ndi madotolo, mapiritsi a Foromu amathandizira kuti pakhale zakudya zochepa zama calorie ndipo amatha kuthandizira kuchepetsa kuwonda kwa odwala omwe ali ndi kunenepa kwambiri.

Pali malingaliro oti mankhwalawa amatha kugwiritsidwa ntchito ngati antitumor othandizira, komanso kuchepetsa kuchepa kwa ukalamba. Zizindikiro izi sizinalembetsedwebe, chifukwa zotsatira za kafukufukuyu ndizoyambiriratu ndipo zimafunanso kuyambiranso.

Kodi metformin kapena formin yabwino ndi chiani?

Mankhwala onse awiri, chinthu chachikulu chomwe chimagwiritsidwa ntchito ndi chinthu chimodzi - metformin. Pankhaniyi, mphamvu zamankhwala ndizofanana. Komanso ndalama izi zimasinthana.

Kukhala wamkulu! Dokotala adakhazikitsa metformin. (February 25, 2016) METFORMIN ya matenda ashuga komanso kunenepa kwambiri.

Dokotala wokhayo ndi amene angadziwe mankhwala omwe ali abwino kwa wodwala aliyense, kutengera momwe alili.

Potere, m'badwo, momwe thupi limakhalira, momwe wodwalayo alili, mawonekedwe ndi kuuma kwa matendawo zimawerengedwa.

Ndi matenda ashuga

Mu matenda a shuga a mtundu woyamba, pakakhala kuphwanya kwathunthu kapena pang'ono pazomwe zimapangidwira insulin, Metformin ndi Formmetin amagwiritsidwa ntchito kuti achepetse kuchuluka kwa inshuwaransi, kuwonjezera mphamvu ya mankhwala, kusinthira ku mitundu yatsopano ya insulin (kukhala otetezeka panthawiyi), komanso kupewa kunenepa kwambiri.

Mu matenda a shuga amtundu wachiwiri, mankhwalawa amayenera kumwa pafupipafupi. Amathandizira wodwalayo atavulala kwambiri minyewa yomwe imayamba kutulutsira insulin. Chifukwa cha njirazi, mwayi wokhala ndi zovuta za matenda a shuga umachepa.

Mukamachepetsa thupi

Metformin ndi formin samangokhala ndi shuga, komanso zimachepetsa kuchuluka kwa lipoproteins, cholesterol ndi triglycerides m'magazi. Chifukwa cha izi, amagwiritsidwa ntchito ngati chowonjezera pa chakudya. Chilichonse chophatikizika mumakina chimathandizira kuti muchepetse kunenepa.

Mankhwala a classainin antidiabetic biguanide kalasi

Malangizo a formethine ogwiritsira ntchito amadziwika kuti ndi mankhwala othandizira odwala omwe ali ndi vuto la Biguanide. Chilendo cha mankhwalawa ndizogwiritsidwa ntchito mosiyanasiyana: mapiritsi angagwiritsidwe ntchito pochiza matenda amishuga a 2, tengani Foromu ndi omwe mtundu wawo wanenepa kwambiri samalola kuti muchepetse thupi kokha kudzera mu zakudya komanso masewera.

Ambiri odwala matenda ashuga amaloleza chithandizo mosavuta, zotsatira zosayenerera zimachitika mosavuta ngati malangizo ndi malamulo operekedwa ndi adotolo sanatsatidwe. Mtundu wa malangizo omwe ali patsamba lino amasinthidwa, amathandizidwa ndi owunika ndi ndemanga. Ndikosatheka kuzimva ngati chitsogozo chodzidzipangira nokha.

Mlingo wa Mlingo ndi malo osungira

Kunja, mankhwalawa amawoneka ngati piritsi loyera loyimbira loyera lokhala ndi mzere wogawika wopanda kukoma kapena kununkhira kwapadera.Mapiritsiwo amakhala ndi matuza, mu bokosi pamakhala zidutswa 10 kapena 12 za mitundu yosiyanasiyana: 0,5 g, 0,85 g kapena 1 g iliyonse. Amapangidwa kuti azigwiritsa ntchito pakamwa.

Mankhwalawa safuna mikhalidwe yapadera kuti asungidwe. Pamtunda wofunda (+ 25 ° C) kutali ndi kuwala kowala ndi chidwi cha ana, Fomu likhoza kusungidwa kwa zaka 2 - moyo wa alumali ukusonyezedwa phukusi. M'tsogolomu, mankhwalawa ayenera kutayidwa.

Limagwirira a zochita za formin

Gawo loyambirira la mankhwala ndi metformin hydrochloride. Kuphatikiza pazogwira ntchito, palinso zokopa zomwe zimapangidwa: magnesium stearate, croscarmellose sodium, povidone.

Mphamvu za Formetin, zomwe chithunzi chake chitha kuwonekera m'gawoli, ndizambiri:

• Lowers glycemia
• Kuchulukitsa chidwi cha insulin,
• Imalepheretsa mayamwidwe a shuga,
• Ilamulira kagayidwe ka lipid:
• Sichimupangitse kulemera.

Mankhwala samathandizira kupanga insulin ya insulin, ma β-cell a kapamba, omwe amachititsa kuti pakhale kapangidwe kake, osadzaza. Metformin imatengedwa mwachangu: nsonga ya kuchuluka kwake imawonedwa patatha maola awiri.

Ubwino wina wa metformin ndi kuyanjana kochepa ndi mapuloteni amwazi. Formetin siyabwino pakukula kwa hypoglycemia. Gawo lolimbikira limadziunjikira mu minofu, impso, chiwindi, tiziwalo timene timagwira. Imapukutidwa makamaka ndi impso. Kuwunika kwa metformin kumatheka pokhapokha ndikuwonetsa matenda a impso. Pambuyo pa ola limodzi ndi theka, kumasulidwa kwa chinthu chogwira ntchito ndi mkodzo kumayamba.

Popeza mankhwalawa ali ndi katundu wowonjezera pamtundu wa genitourinary, mawonekedwe a impso ndi matenda ashuga amayenera kuwunikiridwa kawiri pachaka.

Ngati myalgia akukayikira, kupezeka kwa lactate m'mayesero amwazi kuyenera kuwunikidwa.

Momwe mungamwere mapiritsi

Mlingo wa tsiku ndi tsiku wa mankhwalawo nthawi zambiri amagawika pawiri. Malingaliro olondola kwambiri amakonzedwa ndi adokotala. Chithandizo chimayamba ndi Mlingo wochepa (0.5-0.85 g / tsiku), kamodzi pa sabata endocrinologist amatha kusintha mlingo kutengera zotsatira za kuyezetsa magazi. Mulingo woyenera ndi 3 ma PC / tsiku.

Metformin nthawi zambiri imatengedwa mphindi 20 asanadye. Kenako magawo azakudya ndi mankhwala amanjana.

Kudumpha zakudya mukatha kumwa mankhwalawa ndizowopsa: mutha kuyambitsa shuga.

Forimetin imatengedwa momasuka ndi odwala matenda ashuga omwe amayendetsa kayendedwe kazinthu zovuta, chifukwa sizimayambitsa zotsatira zosasangalatsa zomwe zimachepetsa chidwi komanso kuthamanga kwa zomwe zimachitika.

Pazovuta zovuta, zovuta zimatha, chifukwa chake, mfundo zoterezi zimayenera kufotokozedwa ndi endocrinologist.

Ndani amalimbikitsidwa komanso pamene mankhwalawa apangika

Formetin adapangidwa kuti azilamulira matenda ashuga amtundu wa 2. Imakhala ndi jakisoni wa insulin pophatikiza mankhwalawa, angagwiritsidwe ntchito ngati mankhwala osinthika ngati zakudya zosinthika (zakudya zama carb ochepa, zochitika zolimbitsa thupi zokwanira) sizipereka zotsatira zomwe zikuyembekezeka.

Zabwino za piritsi kukonzekera

Zizindikiro zazikulu pakugwiritsa ntchito mankhwalawa ndi motere:

• kukhalapo kwa metabolic syndrome kapena mawonekedwe a insulin kukana,
• Monga lamulo, pamaso pa insulin kukana, kunenepa kumakula kwambiri mwa odwala, chifukwa cha zotsatira za metformin komanso kuyang'anira zakudya zapadera zamagulu, kuchepa thupi pang'onopang'ono kumatheka.
• ngati pali kuphwanya kwa kulekerera kwa glucose,
• Matenda a ovary ovulala kwambiri,
• shuga yodalira matenda a shuga monga monotherapy kapena gawo limodzi la chithandizo chovuta kwambiri,
• mawonekedwe a shuga omwe amadalira insulin molumikizana ndi jakisoni wa insulin.

Ngati tiyerekeza mankhwala a Fomutiamu ndi mankhwala ena ochepetsa shuga, zotsatirazi zazikuluzikulu za metformin ziyenera kufotokozeredwa:

1. Zake pakuchepetsa kukana kwa insulin wodwala. Metformin hydrochloride imatha kuwonjezera kukhudzika kwa maselo ndi minyewa ku glucose wopangidwa ndi kapamba.
2. Kutenga mankhwalawo kumayendetsedwa ndi mayamwidwe ake ndi ziwalo zam'mimba. Chifukwa chake, kuchepetsa kuchepa kwa shuga ndi matumbo kumakwaniritsidwa.
3. Imathandizira kuletsa shuga wa chiwindi, zomwe zimatchedwa kuperekera shuga.
4. Zimathandizira kuchepetsa kulakalaka, komwe ndikofunikira kwambiri kwa odwala matenda ashuga onenepa kwambiri.
5. Zimakhala ndi phindu pa cholesterol, kuchepetsa zoyipa ndikuwonjeza zabwino.

Kuphatikiza apo, mankhwalawa amathandizira kuti magawo azikhala ochepa.

Malangizo ogwiritsira ntchito mapiritsi

Sonyezani shuga kapena kusankha jenda

pa malingaliro

Zindikirani zaka za mwamunayo

Sonyezani zaka za mkazi

Malangizo a formethine ogwiritsira ntchito ali ndi kunena kuti mankhwalawa amapezeka piritsi la mawonekedwe a biconvex oyera mapiritsi.

Kuphatikizika kwa mankhwalawa kumaphatikizapo ntchito yogwira ntchito ya Metformin hydrochloride ndi zigawo zina zothandizira mu mawonekedwe a magnesium stearate, povidone ndi croscarmellose sodium.

Mlingo wotsatira wa mankhwalawa amaperekedwa pamsika wa pharmacological - 0,5 g, 0,85 g ndi 1 g yogwira ntchito. Kutengera ndi kuopsa kwa hyperglycemia, dokotala amapereka mankhwala omwe amafunikira. Mapiritsi onse a formin amatha kugulidwa m'makatoni a zidutswa 30, 60 kapena 120. Kugwiritsa ntchito kwawo ndizotheka pokhapokha ngati adokotala adanenanso (masiku ano azimayi ambiri amagwiritsa ntchito njira yochepetsera thupi).

Njira yoyendetsera ndi kumwa Mlingo wakhazikitsidwa kwa wodwala aliyense payekhapayekha, kutengera magawo ake:

• kuopsa kwa matenda komanso kuchuluka kwa kuchuluka kwa shuga m'magazi
• gulu la odwala ndi odwala and
• kukhalapo kwa matenda oyanjana.

Musanayambe chithandizo, ndikulimbikitsidwa kuyesedwa ndikuyesedwa kuti mupeze zoopsa zomwe zingachitike ndikuwonetsa kugwiritsidwa ntchito molakwika mukamagwiritsa ntchito mankhwalawa.

Mankhwala Formetin, monga lamulo, amatengedwa molingana ndi malingaliro otsatirawa:

1. Pakamwa pakudya, kumwa madzi ambiri.
2. Mankhwala oyambira ayenera kuyamba ndi kuchuluka kwa ntchito yogwira ndipo akhale ma milligram mazana asanu patsiku.
3. Pakumapeto kwa nthawi (nthawi zambiri pakadutsa milungu iwiri), adotolo, kutengera zotsatira za mayeso ndi kuchuluka kwa glucose m'magazi, amapanga chisankho pakusintha kwa mankhwalawa. Tiyenera kukumbukira kuti pafupifupi tsiku lililonse mlingo wa 500 mpaka 1000 mg wa yogwira metformin hydrochloride.
4. Kuchuluka kwa mankhwala osokoneza bongo omwe amapezeka patsiku sikuyenera kupitirira 3000 mg ya mankhwala othandizira, kwa anthu achikulire chiwerengerochi ndi 1000 mg.

Mutha kumwa formin kamodzi kapena kangapo patsiku, kutengera mtundu womwe wakhazikitsidwa.

Ngati wodwala akufunika Mlingo wambiri wa mankhwalawa, ndibwino kumawagawaniza kangapo patsiku.

Mawonekedwe olakwika a mankhwala

Mankhwala amatha kusokoneza thupi, kuwonetsa zochita zake zoipa.

Kuti muchepetse chiwopsezo cha kupezeka kwawo, ndikofunikira kutsatira malangizo onse a akatswiri azachipatala.

Ndikulimbikitsidwanso kuti muzolowere zomwe mukudziwa zomwe zimapezeka piritsi.

Zotsatira zoyipa zomwe zimachitika chifukwa chotenga mapiritsi a Formetin, mosatengera Mlingo,

• kupezeka kwa mavuto osiyanasiyana ndi m'mimba thirakiti. Izi ndi, zoyambirira, monga kupusa mseru ndi kusanza, kutsegula m'mimba, kutuphuka ndi kukomoka pamimba.
• mankhwala kumawonjezera chiopsezo cha anorexiaꓼ
• mwina kusintha kwa kakomedwe, komwe kumawonekera pakachitika chinthu chosasangalatsa chachitsulo chamkati pamlomo
• kuchepa kwa vitamini B, kumakukakamizani kuti mumwe mankhwala ena owonjezera ndi mankhwala othandizira ꓼ
• chiwonetsero cha kuchepa magazi
• ndi bongo wambiri, pamakhala chiwopsezo cha hypoglycemiaꓼ
• mavuto ndi khungu, ngati pali kuwonetseredwa kwa thupi lawo siligwirizana.

Odwala ena amawona kuti formin ndi antiotic. M'malo mwake, mankhwala sakhala m'gulu la mankhwala otere. Nthawi yomweyo, kwa ana, kugwiritsa ntchito mankhwala kuti athetse hyperglycemia ndi koletsedwa.

Zotsatira zoyipa zimathanso kuchitika chifukwa chogwiritsa ntchito molakwika mankhwalawo kapena pogwiritsa ntchito mankhwala enaake. Kuphatikiza Fomu ndi zida zina zamankhwala (mwanjira ya mapiritsi, kuyimitsidwa, mayankho a jekeseni amakalasi osiyanasiyana ndi magulu) ndizotheka kokha mwa chilolezo cha katswiri wazachipatala.

Kodi zoletsa kugwiritsa ntchito mankhwalawa ndi ziti?

Kuponderezedwa kwa formethine kumasonyezedwa patsamba lamasamba mpaka kukonzekereratu.

Wopanga amafotokozera anthu onse omwe angakhale ogwiritsa ntchito mwatsatanetsatane za milandu yomwe sikovomerezeka kugwiritsa ntchito mankhwalawa.

Kuphatikiza apo, malangizowo ali ndi chidziwitso chomwe formmetin imagwirizana ndi omwe mankhwalawa ndi zinthu.

Sizoletsedwa kumwa mankhwala ngati zotsatirazi zadziwika:

1. Acidosis mu mitundu kapena pachimake.
2. Atsikana pa nthawi yobereka mwana kapena yoyamwitsa.
3. Odwala a zaka zopuma pantchito, makamaka atatha zaka makumi asanu ndi limodzi ndi zisanu.
4. Kusagwirizana ndi gawo la mankhwalawa, chifukwa kuyambitsidwa kwa ziwengo zovuta kumatheka.
5. Ngati wodwala wapezeka ndi vuto la mtima.
6. Ndi vuto lapamtima lakale ndi matenda ashuga.
7. Ngati hypoxia imachitika.
8. Pakusowa kwamadzi, komwe kumayambanso chifukwa cha matenda osiyanasiyana opatsirana.
9. Kugwira ntchito kwambiri.
10. Matenda am'mimba, kuphatikizapo kukhalapo kwa zilonda.
11. Kulephera kwa chiwindi.

Kuphatikiza apo, kuphatikiza kwa chithandizo chamankhwala ndi mowa (mowa pakuwonetsedwa kulikonse) sikovomerezeka.

Ngati wodwala ali ndi ntchito ya impso, chiopsezo chokhala ndi lactic acidosis chitha kuchuluka, popeza kuchuluka kwa lactic acid mthupi kumayamba kudziunjikira.

Kodi Metformin ndi chiyani?

Metformin ndi wa gulu la pharmacotherapeutic - mankhwala ochizira matenda a shuga. Ndi mankhwala ochepetsa shuga kuti mugwiritse ntchito pakamwa.

Limagwirira ntchito a Metformin

Mphamvu zakuchiritsa za Metformin zimawonetsedwa pakuchepetsa kwa matenda ndi kuwonda. Chotsatira chofunikira ndikuchepetsa kwa mayamwidwe a glucose m'matumbo pomwe akuwonjezera kutulutsa kwake. Mphamvu ya Metformin pa kapamba ndikuti imayambitsa kutulutsa insulin.

Kupanga kwa mapiritsi Metformin

Amapezeka mu kipimo cha 500, 850 ndi 1000 mg.

Piritsi lililonse limakhala ndi zinthu zina zogwira ntchito ndi zinthu zina zothandiza: cellcrystalline cellulose, madzi, magnesium stearate, povidone, croscarmellose sodium.

Ubwino ndi Ma Metformin a Metformin

Ubwino wa Metformin watsimikiziridwa pofotokoza kusintha kwa matenda a shuga a 2. Zizindikiro zogwiritsidwa ntchito ndizokhazikitsidwa ndi matendawa.

1. Kwa odwala akuluakulu mawonekedwe awo oyera kapena limodzi ndi njira zina.
2. Kwa ana a zaka 10 kapena insulin.

Metformin yokhudza matenda ashuga

The antiglycemic katundu wa mankhwala bwino. Imayitanitsa:

1. Kuchepetsa chakudya.
2. Kupititsa patsogolo kwa kusintha kwa monosaccharides kuti akonze.
3. Ndime yofulumira ya glucose kudzera minofu.
4. Mitengo yotsika kwambiri ya triglyceride.

Kuunika kwa chithandizo ndi Metformin kunachitika ndi asayansi ambiri ndipo kuwululira mphamvu yayitali.

Ichi ndi mankhwala amkamwa a hypoglycemic ochokera ku banja la Biguanide. Amadziwika kuti woyamba kukhala woyamba antidiabetesic monotherapy pochizira odwala omwe adapezeka ndi matenda a 2. Katundu wa mankhwala amalola kuti ligwiritsidwe ntchito poyimitsa zizindikiro mwa odwala omwe ali ndi zaka zambiri. Odwala ena, kulephera kugwiritsa ntchito kuti akwaniritse kuyendetsa glycemic kosatha kumapangitsa kulumikizidwa kwa othandizira ena odwala.

Cholinga chachikulu chovomerezeka ndi kukhazikika kwa glucose wamagazi ndikuchepetsa kwa kuchuluka kwa zovuta. Ubwino ndi kuvulaza kwa Metformin mu prediabetes ndi madokotala akhala akuphunzira kwambiri kwazaka zambiri. Katundu wa zinthuyu amaletsa kukula kwa matendawa.

Kutenthetsa kwa Metformin

Ntchito yofunikira ndikuthandizira njira yochepetsera kunenepa. Malinga ndi kafukufuku wina, chinthu chogwira ntchito chimachepetsa njala, chomwe chimathandiza kwambiri pochepetsa mawonedwe. Mankhwalawa sangolembedwera kuchepa thupi kokha, koma katundu wake amalola kukhudzidwa kwathunthu ndi matendawa. Phindu lalikulu lidzakhala kuphatikiza kwa Metformin ndi zakudya zama carb ochepa komanso kuchita masewera olimbitsa thupi mwamphamvu.

Metformin imalembedwa kwa anthu athanzi omwe ali ndi mapaundi owonjezera. Pankhaniyi, muyenera kupimidwa pafupipafupi, kuunika kuchuluka kwa magazi, makamaka kuchuluka kwa shuga, cholesterol ndi michere ya chiwindi.

Zambiri polandila ndi Mlingo wa Metformin

Mankhwalawa amalembedwa ndi adokotala mosamalitsa kuti apewe kuvulala. Malangizo apadera akukhudzana ndi kuchuluka kwa kuchuluka kwa mlingo. Izi zimachepetsa chiopsezo ndikuwonjezera phindu.

• piritsi limodzi la 500 mg pakudya kadzutsa kamodzi kapena sabata limodzi,
• mlingo womwewo 2 pa tsiku 1 sabata,
• sabata yakuvomerezedwa katatu patsiku.

Ngati kulephera kwakanthawi kwa muyezo wapezeka ndi dokotala, dokotalayo angaganize kuti musinthe ndikusintha katundu pang'onopang'ono.

Anthu okalamba sayenera kumwa zoposa 1 g patsiku, kuti apewe kuvulaza.

Ndi bwino kumwa mankhwalawo ndi chakudya, chifukwa zimawonjezera kuyamwa m'mimba ndikuchepetsa mavuto - m'mimba kukokana, nseru. Mukamamwa Metformin kumayambiriro kwa chithandizo chamankhwala komanso musanadye, matenda am'mimba amatha.

Kugwiritsa ntchito Metformin pamimba yopanda kanthu sikofunikira chifukwa chakuchepa kwa ntchito ndi vuto chifukwa chakukwiya kwambiri kwa m'mimba. Usiku, Metformin sidzapindulanso ngati dokotalayo sanapange mwayi wa chiwembu chotere. Pofuna kuti musayiwale kumwa mankhwalawa, muyenera kuyeserera kumwa monga momwe munapangidwira - nthawi yomweyo. Mfundo yofunikira ndikukhazikitsa alarm kuti ikumbukireni.

Metformin Yovuta ndi zoyipa

Mankhwala amatha kubweretsanso mavuto ena. Vuto limakhalapo munthu akangoyamba kumwa mankhwalawa, koma nthawi zambiri pakatha milungu ingapo kusamvana kumatha. Zovuta zilizonse ziyenera kudziwitsidwa kwa asing'anga kuti atsimikizire phindu lokha kutsatira.

Zotsatira zoyipa kwambiri:

• kutentha kwa mtima
• kupweteka m'mimba
• kusanza kapena kusanza
• kapangidwe ka mpweya
• kutsegula m'mimba
• kudzimbidwa
• chifuwa
• migraine
• kulawa kwazitsulo mkamwa.

Katundu woyipa akhoza kukhala woopsa kwambiri. Amatha kuvulaza kwambiri anthu omwe ali ndi matenda a impso komanso chiwindi. Chimodzi mwazinthu izi ndi lactic acidosis - kudzikundikira kwa lactic acid mu minofu. Kuvulaza kumawoneka pachiwopsezo cha atrophy ya minofu.

Mwa odwala ena, kuperewera kwa vitamini B12 kumachitika, zomwe zimapangitsa kuvulaza kwamanjenje. Izi zimatha kudzetsa matenda a stroke, kuchepa magazi, komanso kukhumudwa.

Nthawi zina, kuvulaza mwa mtundu wa hypoglycemia kumachitika ngati mankhwala aphatikizidwa:

• ndi zakudya zopanda thanzi,
• zolimbitsa thupi,
• kuvutitsidwa kwa ethanol,
• mankhwala ena am'magazi omwe ali ndi matenda osakhazikika.

Contraindication potenga Metformin

Mankhwalawa amatha kuvulaza thupi. Zoyipa zotsutsana ndi izi:

• pali matenda a chiwindi ndi impso,
• wapezeka ndi vuto la mtima komanso matenda oopsa,
• kumwa mowa pafupipafupi.
• kusowa kwamadzi
• ntchito pamaso maphunziro a x-ray, tomography, ntchito,
• mavuto pambuyo sitiroko,
• mimba ndi mkaka wa m`mawere
• zaka mpaka 10 ndi zaka zoposa 70.

Kugwirizana kwa Metformin ndi mankhwala ena

Mankhwala ena amasokoneza ntchito yogwira ntchito ya Metformin ndipo imatha kuvulaza wodwalayo limodzi ndi iye.

Ngati mukugwiritsa ntchito zilizonse zotsatirazi, mungafunike kuwunika kuchuluka kwa shuga komanso kusintha momwe mulili:

• mapiritsi a steroid, mwachitsanzo, prednisone,
• okodzetsa monga furosemide,
• mankhwala ochizira matenda amtima komanso kuthamanga kwa magazi,
• maimuna achimuna ndi achikazi monga testosterone, estrogen ndi progesterone,
• anticoagulants
• mankhwala ena a shuga.

Amayi ena adzafunikira kusintha pang'ono kwa Metformin atangoyamba mapiritsi oletsa kubereka. Mankhwala a Hormonal ali ndi mphamvu yowonjezera shuga.

Kuphatikiza kwa Metformin ndi Mowa

Kugwiritsidwa ntchito kwa Ethanol kumawonjezera chiopsezo cha hypoglycemia ndi lactic acidosis. Mu malangizo, kugwiritsa ntchito palimodzi nkoletsedwa.

Ma Analogs a mankhwalawa ndi omwe ali ndi chinthu chofanana - ichi ndi Siofor, Bagomet, Glyukofazh, Formmetin, Glformin. Zawo ndi zofanana kwambiri. Osasankha mapiritsi pamalangizo a dokotala, ndi adokotala okha omwe angapereke malingaliro. Phindu lomwe mungayembekezere lodzilowetsa ndekha silingakhale.

Phindu ndi zovuta za Metformin zimatha kungoyesedwa payekhapayekha, kutengera njira ya matendawa komanso kuyang'aniridwa ndi dokotala. Metformin amachepetsa shuga m'magazi ndikumachepetsa matenda ashuga a 2. Ndi mtundu 1, khansa komanso kuchepa thupi, pamakhala zotsatira zabwino kuchokera ku mayeso azachipatala. Palinso chidziwitso chazinthu zabwino za Metformin za ovary ya polycystic, koma pokhapokha ngati kuphwanya glucose kumachitika. Mapiritsi omwe amadzipaka okha sakanenedwa kuti apewe kuvulazidwa.

Kravtsova Victoria, endocrinologist, Taganrog

Metformin imalembedwa kwa odwala omwe ali ndi matenda ashuga a 2. Kwambiri ololera. Palibe zovuta zoyipa zomwe zidadziwika. Ndikukhulupirira kuti phindu limawonekera bwino mu monotherapy, pomwe mankhwalawo amawonetsa bwino zomwe ali.

Seregina Tatyana, endocrinologist, Perm.

Metformin imalembedwa kwa odwala matenda ashuga. Asanaikidwe, amayesedwa mozama kuti apewe ngozi. Ndimayesetsa kuyang'ana mochitira ndimalingalira za phindu la wodwalayo. Mwambiri, odwala amalekerera mankhwalawo osakhala oyipa, phindu lawo limawonekera. Anthu angapo anali ndi matenda am'mimba kwa kanthawi kochepa, kunalibe zodandaula zina. Sindinachitepo kanthu m'malo, popeza momwe mankhwalawo amafananira ndi omwe adanenedwa ndi wopanga.

Ndemanga yakuchepetsa thupi komanso kutenga

Pavlyuchenko Irina, Kostroma.

M'chaka chonsecho, kunenepa kwanga kunachepa. Kutayika konse kunali 19 kg. Munthu akhoza kusangalala ndi izi, koma matenda amtundu wanga adakula. Ndinafunika kusiya kumwa ndikuyamba kubwezeretsa m'mimba. Komabe, ndinganene kuti mankhwalawa ndiwothandiza kuti muchepetse kunenepa. Mwina pambuyo pake ndiyambanso kumwa. Mantha kwambiri kuti mukhale bwino.

Ignatova Anna, Pyatigorsk.

Saw Metformin yopulumutsa matenda ashuga kwa miyezi isanu ndi umodzi. Zidakhala zothandiza kwambiri kwa ine, kuphatikiza ndidataya 8 kg. Ndibwereza maphunzirowa kuphatikiza zotsatira. Dokotala wanga amandiwonetsa kutipumula kwa mwezi umodzi ndikupitilirabe.

Kodi nkhaniyi idakuthandizani?

Mbali ya momwe mankhwalawo alili

Odwala ena amati akumwa mankhwalawa sanafune kudya zakudya zamafuta kwambiri komanso zomanga thupi. Izi zikusonyeza kuti Siofor amathandiza kulimbana mapaundi owonjezera. Ngakhale madotolo adatsimikizira kuti mankhwalawa amatha kuchepetsa njala, zomwe zimapangitsa kuti achepetse thupi.

Tiyenera kumvetsetsa kuti kugwiritsa ntchito mapiritsi nthawi zonse kungakhudze mkhalidwe waumoyo. Makamaka ngati munthuyo alidi wathanzi, ndipo alibe kudwala matenda ashuga.

Kuphatikizika kwa mapiritsiwo kuli ndi metamorphine, yomwe imatha kuchepetsa cholesterol m'mwazi, komanso kumva kumenyedwa. Cholinga chachikulu cha mapiritsiwo ndi kuthandiza anthu omwe ali ndi matenda ashuga. Koma chifukwa cha katundu wawo, iwo amatengedwa ndi anthu athanzi lathunthu, nthawi zambiri, amadalira zotsatira zogwira ntchito zomwe sizichita khama kwambiri.

Mapiritsiwa amatengedwa ndi atsikana athanzi omwe amalota zaumoyo wabwino, koma sangathe kudzipangitsa okha kusiya maswiti komanso zakudya zina. Chifukwa chake, mankhwalawa amathandizira kukonza zakudya komanso kupanga moyo wathanzi chizolowezi.

Ubwino ndi zovuta za Formethine

Mankhwalawa ndi amodzi mwa oyamba omwe amapatsidwa kunenepa kwambiri komwe kumayenderana ndi matenda osokoneza bongo omwe amadalira shuga. Formetin ndiokwera mtengo, ndalama zosakwana ma ruble 100 pamwezi zimagwiritsidwa ntchito pa mankhwala.

• amalimbana ndi kuchuluka kwambiri mwa kuchepetsa kulakalaka kwa maswiti ndi zoyipa,
• Amachepetsa shuga m'magazi,
• kutalika
• otetezeka komanso opezeka
• chida chachikulu komanso chothandiza
• chogwirira ntchito sichimalowa mu kayendedwe kazinthu ndipo sichimapukusidwa, chimatulutsa mkodzo,
• amachita mwachindunji pamatenda amtundu wa plasminogen activators,
• sizikhudzana ndi kapamba,
• sizisokoneza kupanga insulin.

Zabwino zomwe mankhwalawa amaphatikiza ndi monga kugwiritsa ntchito mankhwalawa monga monotherapy komanso gawo limodzi la zovuta zochizira matenda ashuga. Fomu imaloledwa kugwiritsidwa ntchito limodzi ndi jakisoni wa insulin.

Mankhwala amachepetsa cholesterol yoyipa, pamene ikuthandizira kuwonjezera kuchuluka kwa cholesterol yabwino.

Zoyipa zake ndi monga:

• kufunika kotenga nthawi yomweyo
• zimayambitsa mavuto am'mimba, monga kusanza, kusanza, kutsegula m'mimba, kupweteka kwam'mimba,
• Mlingo wokhawo sungathe kuchuluka, ungayambitse matenda a anorexia,
• nthawi yomweyo muyenera kutenga mavitamini a B,
• sikowoneka bwino kumeza mapiritsi chifukwa cha kukula kwake kwakukulu ndi mawonekedwe ake.

Forethine imatha kuvuta kwambiri momwe wodwalayo alili. Nthawi zina, zimayambitsa kunjenjemera, chizungulire komanso kuperewera, kufooka komanso kugona.

Simungamwe kumwa mwachangu mlingo waukulu, kutsekula m'mimba pankhaniyi sikungapeweke (mpaka 10 pa tsiku). Ndikofunikira kuyamba ndi mlingo wochepa. Chifukwa chake thupi limazolowera mankhwalawa, sizimayambitsa mavuto ambiri.

Ubwino ndi zoyipa za Metformin

Amadziwika kuti ndi woyamba mzere mankhwala ochizira matenda a shuga a mtundu wachiwiri. Kuphatikiza kwakukulu ndikuti samayambitsa hypoglycemia.

Kuzindikira kwa shuga - ingomwani tsiku lililonse.

The yogwira pophika mankhwala linalake ndipo tikulephera mapangidwe a dextrose mu chiwindi, kutsitsa ndende yake m'magazi.

Ubwino wachiwiri wa mankhwalawa ndikuti umachepetsa kudya ndipo samayambitsa kulemera, umalimbana ndi kunenepa kwambiri.

Kuphatikiza kwachitatu kwa mankhwalawa ndikotheka kuti mugwiritse ntchito limodzi ndi insulin. Mankhwalawa amaperekedwa kwa odwala popanda chizolowezi cha ketoacidosis.

• zimathandiza kuchepetsa kunenepa, ngati mumatsatira malamulo onse,
• imalepheretsa kupanga maselo atsopano amafuta,
• kulimbana ndi insulin kukana.

Kuti mankhwalawa athandizidwe, ndikofunikira kutsatira zakudya. Wodwala matenda ashuga sayenera kupitirira 2500 Kcal patsiku. Ndikofunikira kupatula maswiti, pasitala ndi mbatata.

Zoyipa za mankhwalawa zimaphatikizira mavuto. Zotsatira zabwino, odwala ayenera kulipira ndi thanzi lawo.

• pafupipafupi zotayirira
• kunyansidwa kwambiri atamwa mankhwalawa pamimba yopanda kanthu,
• kufooka ndi wopepuka
• kupweteka kwam'mimba.

Kutsegula m'mimba kumatha mu masabata 1-2. Zotsatira zoyipa pafupifupi nthawi zonse zimatsagana.

Timapereka kuchotsera kwa owerenga tsamba lathu!

Kuyerekezera Mankhwala

Fomu ndi Metformin ndi ma genetic. Mankhwalawa amapangidwa pamaziko a Glucofage yoyambirira. Mankhwala amapangidwa ku Russia, zomwe zimachitika.

Gome: Mapangidwe a mankhwala.

Kusiyana kwapangidwe ndikofunikira. Metformin ili ndi zigawo zina zothandizira, motero, zimatha kuyambitsa zovuta zina.

Poyerekeza kapangidwe ka mankhwalawa, titha kunena kuti Foramu ndiyotetezeka, chifukwa ili ndi zinthu zovulaza.

Kwa mtengo, Metformin ndi Formetin sizosiyana kwambiri. Wotsiriza mankhwala pafupifupi mtengo 58-217 rubles, woyamba - 77-295 rubles.

Mankhwala onsewa amaperekedwa chifukwa cha matenda aimpso osakhazikika, ana osaposa zaka 10, matenda ashuga a ketoacidosis, uchidakwa, matenda osokoneza bongo, kuperewera kwa zakudya zopatsa mphamvu, kukhala ndi pakati, poyizoni wa zakumwa zoledzeretsa, komanso matenda oopsa opatsirana.

Dzina lamankhwalaChogwira ntchitoZowonjezera Metforminmetamorphine hydrochloride (500, 850 kapena 1000 mg)povidone, Mg (C18H35O2) 2(C6H10O5) n, microcrystalline cellulose, Opadry II ((C2H4O) x, macrogol 3350, Mg3Si4O10 (OH) 2, titanium dioxide, E 132, quinoline yachikasu yowonjezera chakudya. Forethinecroscarmellose sodium

Kusiyana kwapangidwe ndikofunikira. Metformin ili ndi zigawo zina zothandizira, motero, zimatha kuyambitsa zovuta zina.

Poyerekeza kapangidwe ka mankhwalawa, titha kunena kuti Foramu ndiyotetezeka, chifukwa ili ndi zinthu zovulaza.

Kwa mtengo, Metformin ndi Formetin sizosiyana kwambiri. Wotsiriza mankhwala pafupifupi mtengo 58-217 rubles, woyamba - 77-295 rubles.

Mankhwala onsewa amaperekedwa chifukwa cha matenda aimpso osakhazikika, ana osaposa zaka 10, matenda ashuga a ketoacidosis, uchidakwa, matenda osokoneza bongo, kuperewera kwa zakudya zopatsa mphamvu, kukhala ndi pakati, poyizoni wa zakumwa zoledzeretsa, komanso matenda oopsa opatsirana.

Zotsatira zoyipa kuchokera m'mimba thirakiti, kagayidwe, hematopoiesis, endocrine dongosolo ndi chapakati mantha dongosolo ndizofanana. Zodziwika kwambiri ndi:

• nseru kutembenukira kusanza
• zimbudzi zotayirira
• anemia yam'magazi,
• hypoglycemia (nthawi zina).

Pharmokinetics ndi pharmacodynamics ndi ofanana. Mankhwala amatha kugwiritsidwa ntchito mosiyanasiyana ngati wodwala ali ndi vuto losagwirizana ndi zina.

Fomu ndi Metformin amasintha momwe wodwalayo amapezeka ndi matenda a shuga. Kuchita kwawo ndikufuna kukonza chidwi cha minofu kuti ipangire insulin.

Mlingo wofananira siwofanana. Fomu ndi Metformin amatengedwa chimodzimodzi. Mlingo umakhazikitsidwa kutengera kuchuluka kwa shuga m'magazi. Imwani mapiritsi osatafuna, kumwa madzi ambiri.

Kupatula mankhwala oyipa, kumwa mankhwalawa kumalimbikitsidwa ndi zakudya. Mlingo wa tsiku ndi tsiku umagawidwa pakudya zingapo.

Madokotala malangizo

Kudziyendetsa nokha pakumwa sikungatibweretsere chilichonse chabwino. Musanagwiritse ntchito Formetin kapena Metformin, muyenera kufunsa dokotala.

Malangizo ochokera kwa madokotala:

• Tengani mlingo womwe mwawonetsedwa. Kupanda kutero, zovuta zamkati ndi kutsegula m'mimba zimawonekera. Awa ndi mankhwala apamwamba kwambiri pochiza matenda ashuga, koma kugwiritsa ntchito kwawo mosavomerezeka sikutetezedwa.
• Mukamamwa kwambiri, zimakuthandizani. Mankhwalawa, komanso milingo yayikulu imatsogolera ku hypoglycemia, makamaka mukamamwa Formetin. Chiwopsezo chotengera mbali iyi ndi Metformin ndiyotsika.
• Onani zina zowonjezera. Othandizira amatha kukhala osiyana, cholinga chake chimatengera izi, makamaka ngati wodwalayo sakhudzidwa ndi chimodzi mwazinthuzi. Zowonjezera zochepa, zimakhala bwino. Alipo ena a iwo omwe akupezeka ku Metformin, zomwe zikutanthauza kuti Formetin ali bwino pankhaniyi.

Ngati mukukayika za mankhwala omwe mwalandira, funsani dokotala. Katswiri wazachipatala yekha ndiamene angadziwe kusiyana pakati pa mankhwalawa ndikukuwuzani chifukwa chake chida chotere ndi choyenera kwa munthu winawake.

Ndemanga Zahudwala

Ndemanga za odwala matenda ashuga ndizosiyana kwambiri. Mankhwala amodzi amathandizira kuchepetsa thupi komanso kuphatikiza shuga;

Kuzindikira kwa matenda osokoneza bongo kunapangidwa mosayembekezereka ndipo nthawi yomweyo adapereka mankhwala a shuga a Metformin aulere. Maphunzirowa atatha, zotsatira zoyesa zinawonetsa kuti kuchuluka kwa glucose kumachepera pang'ono, kulemera kunayamba kuchepa. Ndinayenera kutenga Formetin, koma zotsatira zake zimakhala bwino ndi Metformin.

Ndakhala ndikumwa Metformin kwa miyezi isanu ndi umodzi, ndinali nditamwa kale Formetin. Mankhwalawa onse amagwira ntchito bwino, koma oyambawo ankayambitsa mseru komanso kutsegula m'mimba. Metformin imachepetsa mofulumira, ndipo ndiye kuti salemanso, pambuyo pa maphunziro a Metformin adayambanso kulemera. Malingaliro anga enieni ndikuti Metformin imagwira bwino, ngakhale pali zovuta zoyipa zomwe zimatha kulekerera.

Tatha kufotokozera za mankhwalawo moyerekeza, titha kunena kuti Metformin ndi Formetin ndi ofanana. Mankhwala amasinthasintha ndipo amasiyana m'magawo othandizira okha.

Matenda a shuga nthawi zonse amayambitsa zovuta zakupha. Mwazi wamagazi ochulukirapo ndi woopsa kwambiri.

Aronova S.M. adafotokoza za chithandizo cha matenda ashuga. Werengani kwathunthu

Kodi zikuwonetsa chiyani kugwiritsa ntchito mankhwala othandizira?

Metformin yogwira yogwira imaphatikizidwa ngati gawo m'mankhwala ambiri ochepetsa shuga. Ndi gawo lothandizika kuchokera ku gulu la Biguanides a m'badwo wachitatu ndipo limathandizira kuchepetsa milingo yamagazi.

Pulogalamu ya antidiabetesic imalepheretsa njira ya gluconeogenesis, kayendedwe ka elekitironi mu kupumula kwa ma metachondria. Njira za glycolysis zimakonzedwa, zomwe zimapangitsa kuti chiwonetsero champhamvu cha glucose chikhale ndi zotumphukira ndi maselo; Komanso, metformin imachepetsa mayamwidwe ake kudzera khoma lamatumbo kuchokera ku lumen ya m'mimba.

Chimodzi mwazinthu zabwino za gawo lomwe limagwira ndi chakuti sizimayambitsa kugwa kwamphamvu pama protein m'magazi. Izi zimatheka chifukwa chodziwika kuti metformin satha kulimbikitsa kupanga kwa insulin ya mahomoni m'maselo a pancreatic beta.

Zizindikiro zazikulu pakugwiritsira ntchito mankhwala motengera metformin ndi:

1. Kukhalapo kwa metabolic syndrome kapena mawonekedwe a insulin kukana.
2. Monga lamulo, pamaso pa insulin kukana odwala matenda ashuga, kunenepa kwambiri kumayamba. Chifukwa cha zotsatira za metformin ndikutsatira zakudya zapadera, kuchepa thupi pang'onopang'ono kumatheka.
3. Ngati pali kuphwanya kwa kulolerana kwa shuga.
4. Zikachitika kuti ovarian cleopolycystosis amakula.
5. Pamaso pa shuga mellitus wa mawonekedwe odziimira payekha - monga monotherapy kapena gawo limodzi la chithandizo chokwanira.
6. Ngati wodwala ali ndi matenda ashuga, mawonekedwe omwe amadalira insulin limodzi ndi jakisoni wa insulin.

Ngati tiyerekeza mapiritsi omwe atchulidwa pa metformin ndi mankhwala ena ochepetsa shuga, ndiye kuti tiyenera kuwunikira zabwino zazikuluzikulu za metformin:

• Zake pakuchepetsa kukana kwa insulin wodwala, metformin hydrochloride imatha kuwonjezera kuchuluka kwa maselo ndi minyewa yake ku glucose opangidwa ndi kapamba
• kumwa mankhwalawo kumayenderana ndi mayamwidwe am'mimba, motero, kuchepa kwamphamvu kwa glucose m'matumbo kumachitikaꓼ
• amathandizira kuletsa chiwindi gluconeogeneis, otchedwa glucose complication processensation
• Amathandizira kuchepetsa kulakalaka, komwe ndikofunikira makamaka kwa odwala matenda ashuga kwambiri
• imakhala ndi phindu pa cholesterol, kutsika koyipa ndikuwonjeza zabwino.

Kuphatikiza apo, mwayi wa Metformin ndikuthekera kwake kopetsa bioprocesses ya lipid peroxidation.

Metformin - mitundu, kapangidwe ndi njira yogwiritsira ntchito

Mpaka pano, mutha kupeza zosiyana zamitunduyi piritsi. Kusiyana pakati pawo kungakhale muyezo wa mankhwalawa, kampani yopanga ndi mawonekedwe akumasulidwa (mapiritsi kapena mapiritsi). Kutengera wopanga ndi mtundu wa mankhwalawo, mtengo wa mankhwalawa umasinthanso.

Metformin Teva ndi mankhwala ochepetsa shuga omwe amapangidwa mwanjira ya mapiritsi. Kutengera ndi zomwe dokotala wakupatsani, mutha kugula mankhwalawa pazotsatira zotsatirazi - 0,5, 0,85 ndi gramu imodzi. Kuphatikiza apo, pali mapiritsi a Metfrmin Teva MV omwe ali ndi kuchuluka kwa 500 ndi 750 mg kukhudzana kwanthawi yayitali. Metformin Teva ndi chinthu chakunja chopangidwa ndi kampani yopanga mankhwala ku Israeli.

Metformin Canon ndi chida chachipatala chomwe chikuyambitsidwa pamsika wa pharmacology wa imodzi mwa makampani aku Russia. Mankhwala a hypoglycemic amatha kupangidwa mu milingo ya 0,5, 0,85 ndi 1 gramu ya mankhwala osakaniza a metformin hydrochloride. Fomu yotulutsidwa imawonetsedwa ngati mawonekedwe a makapisozi.

Metformin Canon amathandizira kuchepetsa kuchuluka kwa chakudya chamagulu am'magazi m'magazi a chiwindi, amachepetsa kuyamwa kwa matumbo m'matumbo ndikuthandizira kugwiritsidwa ntchito kwa shuga ndi zotumphukira zama cell mwa kukonza insulin. Mankhwala sangathe kuyambitsa kukula kwa chikhalidwe cha hypoglycemia, zotsatira zabwino zamafuta kagayidwe. Kugwiritsa ntchito mankhwalawa kumathandizira kuchepetsa kuchuluka kwa triglycerides ndi cholesterol yoyipa m'thupi la wodwalayo, zomwe zimathandiza kuchepetsa kulemera kwambiri kwa thupi.

Metformin Richter ndi woimira wina m'gulu lino la mankhwalawa. Ikhoza kugulidwa pamankhwala ofanana omwe atchulidwa pamwambapa. Wopanga ndiye bungwe la Russia-Hungary a George Richter. Mankhwala amathandizidwa kuti odwala achepetse kuchuluka kwa chakudya chamagulu m'magazi, komanso ngati zizindikiro za kunenepa kwambiri zapezeka. Mankhwalawa mosamala kwambiri ayenera kumwedwa ndi odwala atatha zaka makumi asanu ndi limodzi ndi zisanu.

Slovak Pharmacological Company imapatsa ogula ake mankhwala ochepetsa shuga a Metformin Zentiva. Mankhwalawa amawonetsa kwambiri zotsatira za hypoglycemic, amathandizira kuchepetsa kukana kwa insulin, komanso amakhudza bwino njira ya metabolic m'maselo a thupi.

Kodi mfundo yamitengo yamankhwala awa imati chiyani? M'misika yamzindawu mutha kugula mankhwala omwe ali pamwambawa pamitengo zotsatirazi:

1. Metformin Teva - kuchokera ku ma ruble a 77 mpaka 280, kutengera mlingo wa mapiritsi.
2. Metformin Canon - mtengo wake umasiyana kuchokera pa 89 mpaka 130 ma ruble.
3. Metformin Zentiva - kuchokera ku 118 mpaka 200 ma ruble.
4. Metfirmin Richter - kuchokera ma ruble a 180 mpaka 235.

Kusiyana kwakukulu pamtengo wa mankhwala omwewo m'dera la Russian Federation ndi chifukwa cha dera lomwe mankhwalawo adagulitsidwa.

Zotsatira zoyipa zomwe zingachitike?

Kugwiritsa ntchito molakwika kwa Metformin kumatha kuyambitsa zovuta zambiri zomwe zingakulitse thanzi la wodwala yemwe akudwala matenda ashuga.

Kukhazikitsidwa kwa mankhwala kuyenera kuchitidwa kokha ndi adokotala, poganizira mawonekedwe onse a thupi la wodwalayo, kuopsa kwa kupitirira kwa matenda a zam'thupi ndi zovuta zina.

Malangizo ogwiritsira ntchito mankhwalawa akuwonetsa kuthekera kwa wodwala kukhala ndi zovuta zina.

Zotsatira zoyipa zoyipa za mankhwalawa ndi izi:

• kukula kwa mavuto ndi ziwalo zam'mimba, kudzimbidwa, komwe kumatha kutsagana ndi kuchuluka kwa mpweya, kupweteka m'mimba kapena m'mimba,
• utoto wopanda mchere mkamwa utha kuwonekera mutatha kudya,
• kusanza ndi kusanza
• kusowa kwamagulu angapo a mavitamini, makamaka B12, ndichifukwa chake akulimbikitsidwa kuti mitundu ingapo yama mankhwala apadera omwe amatha kusintha mitundu yonse ya zinthu zofunika mthupi
• kukulitsa kwa matupi awo sagwirizana ndi zigawo za piritsi,
• kutsika kwa shuga m'magazi pazomwe zikuwonetsa,
• mawonetseredwe a lactic acidosis,
• megaloblastic anemia.

Metformin ndi yoletsedwa kugwiritsa ntchito pamaso pa chinthu chimodzi kapena zingapo:

1. Metabolic acidosis mu mafupa owopsa kapena aakulu.
2. mkhalidwe wa glycemic coma kapena kholo.
3. Ndi mavuto akulu pantchito ya impso.
4. Chifukwa chakutha kwamadzi.
5. Matenda akuluakulu opatsirana akaonekera kapena pambuyo pawo.
6. Kulephera kwa mtima kapena kulowerera kwamtima.
7. Mavuto ndi magwiridwe antchito amlengalenga.
8. Uchidakwa wambiri

Kuphatikiza apo, ndizoletsedwa kumwa mankhwalawa mutangoyamba kumene kuchita opareshoni (ziyenera kutha masiku osachepera masiku awiri ntchito isanachitike komanso masiku awiri itatha

Mankhwala ndi Foromu

Mankhwala Forethine ndi amodzi mwa oimira gulu la Biguanide. Ichi ndi hypoglycemic, chophatikiza chachikulu chomwe ndi metphromine hydrochloride.

Formetin imakonda kutumikiridwa kwa odwala omwe ali ndi matenda a shuga 2, makamaka ngati matendawa amapezeka ndi kunenepa kwam'mimba.

Mankhwalawa amathandizira kuchepetsa kuchuluka kwa shuga m'magazi, amachepetsa kutulutsa shuga ndi chiwindi, komanso amachepetsa kuyamwa kwake ndi ziwalo zam'mimba. Kuphatikiza apo, kukonzekera kwa piritsi kumakhudza bwino kusalolera kwa chiwonetsero cha insulin, kukulitsa chidwi cha maselo ndi minofu.

Kulandila kwa Formetin ndikotheka kokha malinga ndi zomwe dokotala wakupatsani. Kulephera kutsatira malangizo azachipatala kapena kumwa mankhwala kungapangitse kuti pakhale zovuta zingapo kuchokera mkati ndi ziwalo zamkati.

Tisaiwale kuti zotsatirapo zoyambirira za kutenga formetin zitha kukhala:

• kusanza ndi kusanza
• kupweteka pamimba,
• chisangalalo,
• kuoneka ngati chitsulo chosasangalatsa pamkamwa,
• dermatitis a pakhungu.

Zotsatira zoyipa monga lactic acidosis kapena kuchepa kwa magazi m'maselo a shuga sizingawoneke.

Pakachitika vuto limodzi kapena zingapo zoyipa, mankhwalawo amwe amayenera kusinthidwa.

Ndi piritsi iti yomwe imagwira ntchito kwambiri?

Kodi pali kusiyana kotani pakati pa Metformin ndi Formmetin? Kodi mankhwala amodzi ndi osiyana ndi ena?

Monga tafotokozera pamwambapa, chinthu chomwe ndi Metformin hydrochloride chimagwiritsidwa ntchito ngati chofunikira chachikulu pazida zamankhwala zotere. Chifukwa chake, zotsatira za kumwa mankhwalawa ziyenera kukhala zofanana (mukamagwiritsa ntchito Mlingo womwewo).

Kusiyanaku kungakhale mu zigawo zowonjezera, zomwe zimakhalanso gawo la mapiritsi. Izi ndi zokopa zosiyanasiyana. Mukamagula, muyenera kuyang'anira zomwe ali nazo - ocheperako kuchuluka kwa zowonjezera, ndizabwino. Kuphatikiza apo, dokotala yemwe akupezekapo angalimbikitse kumwa mankhwala ena ake, kutengera mtundu wa wodwalayo.

Posankha mankhwala, munthu amayeneranso kuganizira zinthu monga mtengo wa mankhwalawo. Nthawi zambiri, ma analogi achilendo amakhala ndi mtengo wokwirirapo kuposa mankhwala akwathu. Monga momwe masewera amasonyezera, momwe amalandirira zilinso zosiyana. Mpaka pano, Formetin ndiye njira yabwino kwambiri yowerengera ndalama pakati pa zida zamankhwala zomwe zimakhala ndi metformin hydrochloride.

Ngati wodwala matenda ashuga akukayika kena kake ndipo sakudziwa ngati zingatheke kusintha wina ndi mnzake, muyenera kufunsa dokotala. Katswiri wazachipatala azitha kufotokoza kusiyana pakati pa mankhwala angapo a analogue, ndikufotokozeranso chifukwa chake mankhwalawa ndi oyenera kwa munthu wina.

Zambiri pa Metformin ndi malo omwe amachepetsa shuga zimaperekedwa mu kanema munkhaniyi.

Ndemanga za madotolo za Metformin ndi Formetin

Dmitry, wazaka 56, wodwala matenda a endocrinologist, ku Moscow: "Ndimaona Metformin kukhala yothandiza pochiza matenda a endocrine (matenda a carbohydrate metabolism, matenda a shuga mellitus). Koma ndimawachenjeza odwala kuti nthawi zina amakumana ndi mavuto. Kwa mankhwalawa, izi sizachilendo. Ndimapereka mankhwala pandekha komanso m'njira zovuta kuchipatala. ”

Marina, wazaka 49, wazopeza za matenda a ana, Saratov: “Nthawi zambiri ndimayambitsa matenda a shuga. Ichi ndi mankhwala othandizadi, ndipo ngati mankhwala omwe wapezeka ndi omwe amawonekera, amakhala otetezeka. Kupanda kutero, mavuto amabwera, ena mwa owopsa. ”

Ndemanga za Odwala

Margarita, wazaka 33, Tver: “Zaka zingapo zapitazo ndinadwala matenda ashuga a 2. Dokotala adandipangira Metformin, yomwe ndimatenga jakisoni wa insulin. Mankhwalawa amachepetsa shuga ya magazi bwino. Ndili wokondwa ndi chithandizochi, ndipo sizinakhalepo ndi zotsatila zake. ”

Tatyana, wazaka 29, Kostroma: “Ndinagula fomu motsimikizira dokotala. Sindivutika ndi shuga, koma ndine wonenepa kwambiri. Ndimagwiritsa ntchito mankhwalawa pofuna kuchepetsa thupi kuphatikiza zakudya zamagulu ochepa. Kwa miyezi itatu adataya makilogalamu 10, pomwe khungu lake lidasintha. Ndimakondwera ndi mankhwalawa. "