Thioctacid 600: malangizo, ntchito, zikuonetsa

Thioctacid BV: malangizo ogwiritsa ntchito ndi kuwunikira

Dzina lachi Latin: Thioctacid

Code ya ATX: A16AX01

Yogwira pophika: thioctic acid (thioctic acid)

Wopanga: GmbH MEDA Production (Germany)

Kusintha kwamalingaliro ndi chithunzi: 10.24.2018

Mitengo muma pharmacies: kuchokera ku 1604 rubles.

Thioctacid BV ndi metabolic mankhwala okhala ndi antioxidant zotsatira.

Kutulutsa mawonekedwe ndi kapangidwe kake

Thioctacid BV imapezeka mu mawonekedwe a mapiritsi, ophatikizidwa ndi filimu: wobiriwira wachikasu, oblong biconvex (30, 60 kapena ma PC. M'mabotolo amdima amdima, botolo limodzi mumtolo wa makatoni).

Piritsi limodzi lili:

• yogwira mankhwala: thioctic (alpha-lipoic) acid - 0,6 g,
• othandizira zigawo: magnesium stearate, hyprolose, Hyperose-mmalo otsika,
• makanema ophatikizira amakanema: titanium dioxide, macrogol 6000, hypromellose, varnish aluminium yozikidwa pa indigo carmine ndi utoto wa quinoline chikasu, talc.

Mankhwala

Thioctacid BV ndi metabolic mankhwala omwe amasintha trophic neurons, ali ndi hepatoprotective, hypocholesterolemic, hypoglycemic, ndi lipid-kuchepetsa.

Mankhwala omwe amagwira ntchito ndi thioctic acid, omwe ali m'thupi la munthu ndipo amaletsa antioxidant. Monga coenzyme, imatenga nawo gawo la oxidative phosphorylation wa pyruvic acid ndi alpha-keto acid. Limagwirira ntchito thioctic acid ali pafupi ndi michere ya michere ya B. Amathandizira kuteteza maselo ku poizoni wa zotsatira zoyipa zamagetsi zomwe zimachitika machitidwe a metabolic, komanso zimalepheretsa zinthu zina zakupha m'thupi zomwe zalowa m'thupi. Kuchulukitsa msanga wa amkaka antioxidant glutathione, kumayambitsa kuchepa kwa zizindikiro za polyneuropathy.

Mphamvu ya synergistic ya thioctic acid ndi insulin ndiwonjezere pakugwiritsa ntchito shuga.

Pharmacokinetics

Mafuta a thioctic acid kuchokera m'matumbo am'mimba (GIT) akaperekedwa pakamwa amachitika mofulumira komanso kwathunthu. Kumwa mankhwala ndi chakudya kumachepetsa mayamwidwe. C_max (kuchuluka kwa ndende) m'magazi am'madzi mutangotenga muyezo umodzi umatheka pambuyo pa mphindi 30 ndipo ndi 0,004 mg / ml. Mtheradi wa bioavailability wa Thioctacid BV ndi 20%.

Asanalowe kufalikira kwatsatanetsatane, thioctic acid imadutsa gawo loyambira kudzera mu chiwindi. Njira zazikulu za kagayidwe kake ndi oxidation ndi conjugation.

T_1/2 (theka-moyo) ndi mphindi 25.

Kutupa kwa Thioctacid BV yogwira ntchito ndipo ma metabolites amachitika kudzera mu impso. Ndi mkodzo, 80-90% ya mankhwalawa amachotsedwa.

Malangizo ogwiritsira ntchito Thioctacid BV: njira ndi mlingo

Malinga ndi malangizo, Thioctacid BV 600 mg imatengedwa pamimba yopanda kanthu, maola 0,5 asanadye kadzutsa, kumeza lonse ndikumwa madzi ambiri.

Mlingo woyenera: 1 pc. Kamodzi patsiku.

Popeza kupezeka kwa chipatala, pochizira mitundu yayikulu ya polyneuropathy, kukhazikitsidwa koyambirira kwa yankho la thioctic acid kwa mtsempha wa mtsempha wa magazi (Thioctacid 600 T) ndikotheka kwa masiku 14 mpaka 28, kutsatiridwa ndikusintha kwa wodwala tsiku lililonse chifukwa cha mankhwalawa (Thioctacid BV).

Zotsatira zoyipa

• Kuchokera mmimba: Nthawi zambiri - nseru, kawirikawiri - kusanza, kupweteka m'mimba ndi matumbo, kutsekula m'mimba, kuphwanya kwamva kukomoka,
• Kuchokera kwamanjenje: Nthawi zambiri - chizungulire,
• thupi lawo siligwirizana: kawirikawiri - kuyabwa, zotupa pakhungu, urticaria, anaphylactic mantha,
• mbali ya thupi lonse: kawirikawiri - kuchepa kwamagazi m'magazi, mawonekedwe a hypoglycemia m'mutu, mutu, kusokonezeka, thukuta, komanso kuwonongeka kwa mawonekedwe.

Bongo

Zizindikiro: motsutsana ndi maziko a mlingo umodzi wa 1040 g wa thioctic acid, kuledzera kwambiri kumatha kukhala ndi mawonetseredwe okhudzana ndi kukhudzika kwakukulu, hypoglycemic chikomokere, kusokonezeka kwakukulu mu acid-base usawa, lactic acidosis, kusokonezeka kwamatenda akulu a magazi (kuphatikizapo imfa).

Chithandizo: ngati mankhwala osokoneza bongo a Thioctacid BV akuwoneka kuti ali ndi mapiritsi 10 akulu, mwana woposa 50 mg pa kilogalamu imodzi ya kulemera kwake kwa thupi, wodwalayo amafunikira kuchipatala msanga poika chithandizo chamankhwala. Ngati ndi kotheka, mankhwala a anticonvulsant amagwiritsidwa ntchito, njira zadzidzidzi zofunika kukonza ziwalo zofunika.

Malangizo apadera

Popeza ethanol imakhala pachiwopsezo chotukuka kwa polyneuropathy ndipo imayambitsa kuchepa kwamankhwala othandizira a Thioctacid BV, kumwa mowa kumatsutsana kwambiri ndi odwala.

Pochiza matenda a shuga a polyneuropathy, wodwalayo ayenera kupanga zinthu zomwe zimatsimikizira kuti shuga ipezeka m'magazi.

Contraindication

• ana ndi achinyamata ochepera zaka 18 (palibe chidziwitso pakugwiritsa ntchito mankhwalawa),
• nthawi ya pakati komanso mkaka wa m'mawere (palibe chokwanira pakugwiritsa ntchito mankhwalawa),
• Hypersensitivity kuti ndi thioctic acid kapena mbali yothandizira ya mankhwala.

Mlingo ndi makonzedwe

Mapiritsi a Thioctacid BV amatengedwa pakamwa, osati kutafuna, koma kuwameza athunthu ndikutsukidwa ndi madzi. Mankhwala amatengedwa pamimba yopanda kanthu, m'mawa, mphindi 30 musanadye chakudya cham'mawa.

Mlingo wa tsiku ndi tsiku ndi 600 mg (piritsi 1) kamodzi.

Woonda polyneuropathy, mankhwala amayamba ndi kuyamwa kwamankhwala osokoneza bongo monga njira yothetsera vutoli (Thioctacid 600 T). Pambuyo 2-5 milungu ya mankhwala ndi parenteral mawonekedwe a thioctic acid, wodwalayo asamutsidwa kumwa Thioctacid BV mapiritsi.

Kuyanjana kwa mankhwala

Asidi a Thioctic (α-lipoic) amachepetsa mphamvu ya cisplatin ndipo amatha kupititsa patsogolo mphamvu ya othandizira pakamwa kapena a insulin. Nthawi zina, ndizovomerezeka kuchepetsa mlingo wa mankhwala a hypoglycemic pofuna kupewa kukula kwa zizindikiro za hypoglycemia.

Mowa wa Ethyl ndi metabolites ake amachepetsa mphamvu ya Thioctacid BV.

Ndemanga pa Thioctacide BV

Ndemanga za Thioctacide BV nthawi zambiri zimakhala zabwino. Odwala omwe ali ndi matenda ashuga amawonetsa kuchepa kwa shuga m'magazi ndi cholesterol, thanzi labwino motsutsana ndi maziko amagwiritsidwa ntchito mankhwalawa kwa nthawi yayitali. Chimodzi mwa mankhwalawa ndikutulutsidwa kwa thioctic acid, komwe kumathandizira njira zamatenda ndikuchotsa mafuta achilengedwe m'thupi, kusintha kwa chakudya champhamvu m'mthupi.

Njira yothandiza yochizira imadziwika mukamagwiritsa ntchito mankhwalawa pochiza chiwindi, matenda amitsempha, komanso kunenepa kwambiri. Poyerekeza ndi analogues, odwala amawonetsa kuchepetsedwa kosafunikira.

Mwa odwala ena, kumwa mankhwalawo kunalibe chiyembekezo chozama chochepetsera cholesterol kapena kunathandizira kukulitsa urticaria.

Zisonyezero zogwiritsira ntchito Thioctacid 600

Zizindikiro zogwiritsidwa ntchito ndi Thioctacid 600 ndi:

• matenda ashuga ndi mowa wamphamvu,
• Hyperlipidemia,
• mafuta amchiwindi,
• chiwindi matenda a chiwindi ndi chiwindi,
• kuledzera (kuphatikizapo mchere wa zitsulo zolemera, zodonthetsa zakuda),
• mankhwalawa komanso kupewa coronary atherosulinosis.

Malangizo a Thioctacid 600, mlingo

Mlingo wofanana

Jakisoni Thioctacid 600 amathandizidwa mu / mu (ndege, dontho). Mapiritsi a Thioctacid mazana asanu ndi awiri - kuchuluka kwa 600 mg / tsiku kwa 1 mg m'mawa m'mimba yopanda 30-30 mphindi musanadye kadzutsa, 200 mg katatu patsiku sagwira ntchito kwenikweni.

Zapadera

Mitundu yayikulu ya polyneuropathy - iv pang'onopang'ono (50 mg / min), 600 mg kapena iv drip, mu 0.9% NaCl yankho kamodzi patsiku (muzovuta, mpaka 1200 mg imayendetsedwa) kwa masabata a 2-4. Pambuyo pake, amasinthira ku mankhwala amkamwa (akuluakulu - 600-1200 mg / tsiku, achinyamata - 200-600 mg / tsiku) kwa miyezi itatu. Mu / kumayambitsa ndikotheka ndi mothandizidwa ndi perfuser (nthawi ya makonzedwe - osachepera mphindi 12).

Njira yochizira ndi thioctacid kwa odwala omwe ali ndi matenda ashuga polyneuropathy akhazikitsidwa bwino ndipo ali ndi maziko olimba a sayansi komanso othandiza. Chithandizo cha mankhwalawa chimayamba ndi kuyambitsa thioctacide kudzera mu mtsempha wa 600 mg kwa masabata awiri.

Ndi mankhwala omwewo munthawi yomweyo ndimankhwala amphamvu a Thioctacid, malingaliro a adokotala amayenera kuonedwa mosamala.

Zolemba ntchito

Odwala ambiri amadandaula za nthawi yayitali kuti apereke mankhwala a Thioctacid 600 T mu njira yothetsera kulowetsedwa kwa mtsempha. Ngakhale izi, madokotala amalimbikitsa mtundu uwu wa mankhwalawa koyambirira kwa matenda. Imapinda bwino kwambiri ndipo imakupatsani mwayi woti mulinganize molondola.

Mukamagwiritsa ntchito mankhwalawa, munthu ayenera kupewa kuyendetsa magalimoto ndikugwiritsa ntchito njira zowopsa.

Ngati pakufunika kuperekera limodzi mankhwalawa mankhwalawa, ndiye kuti muyenera kulimbana ndi nthawi yayitali pakati pa kayendetsedwe kake maola asanu mpaka asanu ndi limodzi.

Mankhwala mu ampoules samawululidwa mpaka pakugwiritsidwa ntchito mwachindunji. Njira yotsirizidwa imagwiritsidwa ntchito kwa maola asanu ndi limodzi komanso yotetezedwa pakuwala.

Kumwa mowa kumatha kuchepetsa mphamvu ya mankhwalawa. Chifukwa chake, tikulimbikitsidwa kuti musamwe zakumwa zilizonse zakumwa zoledzeretsa mukamalandira mankhwalawa.

Mosamala, phatikizani ndi othandizira okhala ndi zitsulo, chisplatin, insulin, ndi mankhwala a shuga.

Pa magawo oyambirira a chithandizo, kulimbitsa kosasangalatsa kwa zotheka ndi neuropathy ndikotheka, komwe kumalumikizidwa ndi njira yobwezeretsa kapangidwe ka minyewa yamitsempha.

Zotsatira zoyipa ndi contraindication Thioctacid 600

Ndi kuyendetsa mwachangu kwa Thioctacid 600 T, kupanikizika kwa mkati nthawi zina kumatha kuwonjezeka ndipo kumangidwa kwamapumidwe kumatha kuonedwa. Monga lamulo, izi kuphwanya kumachoka zokha.

Pogwiritsa ntchito Thioctacid nthawi zina, kuchuluka kwa glucose m'magazi kumatha kuchepa (chifukwa cha kusintha kwa magwiritsidwe ake). Pankhaniyi, hypoglycemia imatha kuchitika, zizindikiro zazikulu zomwe ndi: chizungulire, kupweteka mutu, thukuta kwambiri (hyperhidrosis) ndi kusokonezeka kowoneka.

Ndemanga ya thioctacide mu mawonekedwe a jakisoni amatero kawirikawiri milandu yamavuto amanjenje. Ngati mulingo woyenera umaposa kwambiri, zizindikiro za kuledzera zingachitike, zofotokozedwera pansipa.

Bongo

Kuchuluka kwa mlingo wa mankhwalawa kapena kugwiritsidwa ntchito kwa Thioctacid ndi mowa kumatha kuyambitsa zizindikiro za kuledzera kwathunthu.

Pakakhala vuto la bongo, nseru, kusanza, ndi mutu. Pambuyo mwangozi kapena mukamayesera kudzipha pakamwa pa thioctic acid mu Mlingo wa 10 g mpaka 40 g osakanikirana ndi mowa, kuledzera kwambiri kumadziwika, nthawi zina kumatha kupha.

Kumayambiriro kwake, kuledzera ndi mankhwala a Thioctacid BV kumawonetsedwa ndi kukhudzika kwa chikumbumtima ndi vuto la psychomotor. Ndiye lactic acidosis ndi kukomoka kosakhazikika kumayamba. Ndiwowonjezera kuchuluka kwa alpha-lipoic acid, hemolysis, hypokalemia, mantha, kufooka kwamitundu yambiri, rhabdomyolysis, DIC, ndi myelosuppression.

Ngati kuledzera kwakukulu kwa mankhwalawa kukukayikiridwa, kuthandizidwa kuchipatala mwachangu ndi kugwiritsa ntchito miyeso molingana ndi mfundo zodziwika bwino za poyizoni mwangozi ndikulimbikitsidwa (mwachitsanzo, kusanza, kutsuka m'mimba, kutsitsa makala, etc., ambulansi isanafike).

Contraindication

• Hypersensitivity kuti alpha-lipoic acid kapena zigawo zina za mankhwala.
• Ana a zaka mpaka 15.
• Nthawi ya pakati ndi kuyamwa.

Analogs Thioctacid 600, mndandanda

Zofananira zazikulu za Thioctacid pazomwe zimagwira ndi monga mankhwala: Berlition 300, Oktolipen, Lipothioxon, Thiogamma, Lipamide, Tiolept, Thiolipon, Lipoic acid, Espa-Lipon ndi Neurolepone.

Mwa analogues, mtengo wogwira komanso wogwira mtima ndi:

1. Kuvan Mapiritsi,
2. Mapapu Curtain ndi Orfadin,
3. Mankhwala a Homeopathic Gastricumel,
4. Mapiritsi a Bifiform Ana otsekemera.

Chofunikira - malangizo ogwiritsira ntchito Thioctacid 600, mtengo ndi kuwunika sizigwira ntchito pa analogues ndipo sizingagwiritsidwe ntchito ngati chitsogozo pakugwiritsa ntchito mankhwala omwe ali ndi kapangidwe kake. Nthawi zonse zochizira ziyenera kupangidwa ndi dokotala. Mukasankha Thioctacid 600 ndi analogue, ndikofunikira kuti mupeze upangiri waluso, mungafunike kusintha njira zamankhwala, mankhwalawa, etc. Osadziletsa!

Mu matenda ashuga, amakakamizika kutenga maphunziro a Thioctacid 600 kamodzi kapena kawiri pachaka. Ngati mankhwalawa siabwino, ndiye kuti ayenera m'malo mwake ndi analog. Ndikosatheka kukana maphunziro amtunduwu.

Odwala ambiri omwe amagwiritsa ntchito mankhwalawa amawona kuti amagwira ntchito kwambiri polimbana ndi matenda osokoneza bongo komanso kuwononga kuwonongeka kwa minyewa yaziphuphu. Ndemanga ya Thioctacid 600 ikuwonetsa kuchepa kwamphamvu kwa zizindikiro monga kupweteka m'munsi, kusapeza mpumulo, kumva kukomoka komanso kupindika.

Mankhwala Thioctacid

Thioctic acid, yomwe ndi gawo lalikulu la mankhwala, imapangidwa ndi thupi lathanzi pakuchita bwino kwa minofu ndi kupewa kuwonongeka kwa maselo. Thioctacid imathandizira kuwonongeka kwa ma cellular ndikutsitsa magazi m'magazi chifukwa cha kusintha kwa kapangidwe ka zipupa zamitsempha yamagazi, kupezeka kwa zolembera za atherosselotic.

Kupanga ndi mawonekedwe a kumasulidwa

Mankhwala amapezeka mu mawonekedwe a mapiritsi otulutsira mwachangu ndi kulowetsedwa. Zilembo zomwe zimaphatikizidwa ndi dzinali zimapangitsa kuti zikhale zosavuta kudziwa mtundu womwe wagulitsidwa. Mankhwala amadziwika ndi zinthu zotsatirazi:

Dzinalo Lopanda Padziko Lonse

thioctacid 600 t

Mapiritsi okhala ndi mafilimu

Njira yothetsera mtsempha wa magazi

Thioctic (alpha lipoic) acid - 600 mg

Hyprolose-wogwirizira wotsika, magnesium stearate

Madzi osalala, trometamol

Mapangidwe a chipolopolo

hypromellose, macrogol 6000, titanium dioxide, talc, varnish ya aluminium

Mapiritsi okhala ndi chikasu chobiriwira wachikaso ndi oblong biconvex

Chikasu chowoneka bwino

Kuchuluka kwa Phukusi

30 kapena 100 mapiritsi

Ma ampoules 5 a 24 ml

Mankhwala

Chida chimagwiritsidwa ntchito kuteteza njira ya metabolic m'maselo. Thioctic acid ndi antioxidant wachilengedwe wopangidwa ndi thupi laumunthu ndipo wokhala ndi ulusi wamitsempha kuti ateteze maselo ku zotsatira zoyipa za mankhwala oyipa - ma free radicals, omwe amapangidwa ndi metabolism. Mu thupi, chinthu chimagwira gawo la coenzyme.

Kukhalapo kwa thioctic acid mumagazi a cellellular ndi cell membrane kumakulitsa kuchuluka kwa glutathione, yemwe amachititsa chiwonetsero cha minyewa. Chithandizo cha matenda amathandizira kuthamanga kwa magazi, kumathandizira kuchepetsa cholesterol ndikuletsa kutalika kwa mitsempha ya magazi, potero kusintha magazi. Kutha kwa alpha-lipoic acid kupangira zochita za insulin kumapangitsa kuti akhale nawo gawo lofunikira pakugwiritsa ntchito shuga pamagulu odwala omwe ali ndi matenda ashuga.

Kuphatikizika, mawonekedwe omasulidwa ndi dzina la thioctacid

Pakadali pano, thioctacid imapezeka m'mitundu iwiri:
1. Mapiritsi otulutsira mwachangu makonzedwe akumlomo,
2. Njira yothetsera kulowetsedwa kwa mtsempha.

Mapiritsi a Thioctacid BV amagwiritsidwa ntchito kamodzi patsiku, 1 tabu.pamimba yopanda kanthu m'mphindi 20-30. chakudya chisanachitike. Nthawi yolandila ikhoza kukhala yabwino kwa wodwala.

Njira yothetsera kulowetsedwa kwa mitsempha imatchedwa molondola Thioctacid 600T . Chifukwa chake, zilembo zingapo zomwe zidawonjezeredwa ku dzina lenileni la mankhwalawa zimapangitsa kuti zosavuta kumva mtundu wa mtundu womwe umakhudzidwa.

Monga yogwira pophika, mapiritsi ndi zolingalira zimakhala thioctic acid (alpha lipoic). Yankho lake ndi mchere wa trometamol wa thioctic acid, womwe umakhala wotetezeka kwambiri komanso wotsika mtengo kwambiri popanga. Zinthu za Ballast kulibe. Tromethamol imagwiritsidwa ntchito pobwezeretsa magazi omwe ali m'magazi. Njira yothetsera vutoli imakhala ndi 600 mg ya thioctic acid mu 1 ampoule (24 ml).

Monga zigawo zothandiza zimakhala ndi madzi osalala a jakisoni ndi trometamol, mulibe ma propylene glycols, ethylenediamine, macrogol, etc. Mapiritsi a Thioctacid BV amakhala ndi kuchuluka kwa maipi, omwe alibe lactose, wowuma, silicon, mafuta a castor, etc., omwe nthawi zambiri amawonjezeredwa ndi mankhwala otsika mtengo.

Mapiritsiwo ali ndi mawonekedwe oblong, a biconvex ndipo ndi achikuda achikuda. Amapezeka m'matumba a zidutswa 30 ndi 100. Njira yothetsera vutoli ndi yowonekera, yopakidwa utoto wachikasu. Wopezeka ma ampoules a 24 ml, mmatumba a 5 pcs.

Thioctacid - kuchuluka ndi zochizira

The yogwira thunthu la Thioctacid nawo metabolism ndi mphamvu zochitidwa mu mitochondria. Mitochondria ndimapangidwe am'm cell omwe amapereka kupezeka kwa chilengedwe chonse mphamvu ATP (adenosine triphosphoric acid) kuchokera kumafuta ndi chakudya. ATP imagwiritsidwa ntchito ndi maselo onse ngati gwero lamphamvu. Kuti timvetsetse za molekyulu ya ATP, imatha kufananizidwa ndi mafuta, omwe amafunikira kayendedwe kagalimoto.

Ngati ATP sikokwanira, ndiye kuti cell siyitha kugwira bwino ntchito. Zotsatira zake, zovuta zina zimangokhala osati m'maselo omwe akusowa ATP, komanso gawo lonse kapena minofu yomwe amapanga. Popeza ATP imapangidwa mu mitochondria kuchokera ku mafuta ndi chakudya, kusowa kwa michere kumangobweretsa izi.

Mu shuga mellitus, uchidakwa ndi matenda ena, mitsempha yamagazi yaying'ono nthawi zambiri imakhala yokhazikika komanso kusayenda bwino, chifukwa chomwe minyewa yam'mitsempha ya minyewa sikulandila michere yokwanira, chifukwa chake, ndiyosakwanira ku ATP. Zotsatira zake, njira ya mitsempha ya mitsempha imayamba, yomwe imadziwonetsera yokha ndikuphwanya kumverera kwazinthu zamkati ndi magalimoto, ndipo munthu akumva ululu, kuwotcha, kumva tulo ndi zina zomverera zosasangalatsa m'dera lomwe minyewa yomwe yakhudzidwa idutsa.

Kuti muchepetse kusamvetseka uku ndikumasokoneza, ndikofunikira kubwezeretsa zakudya zama cell. Thioctacid ndi gawo lofunikira mu kayendedwe ka metabolic, ndikutenga nawo gawo komwe kuchuluka kwakukulu kwa ATP kungapangike mu mitochondria, kukwaniritsa zosowa za maselo. Ndiye kuti, thioctacid ndi chinthu chomwe chitha kuthetsa zoperewera pazakudya zam'mimba ndipo, potero, kuthetseratu mawonekedwe owawa a neuropathy. Ichi ndichifukwa chake mankhwalawa amagwiritsidwa ntchito pochiza polyneuropathies ochokera kumitundu yosiyanasiyana, kuphatikizapo chidakwa, matenda ashuga, ndi zina zambiri.

Kuphatikiza apo, Thioctacid imakhala ndi zotsatira za antitoxic, antioxidant ndi insulin. Monga antioxidant, mankhwalawa amateteza maselo a ziwalo zonse ndi machitidwe kuti asawonongeke ndi ma radicals aulere opangidwa pakuwonongeka kwa zinthu zina zakunja (mwachitsanzo, kufuna kwa zitsulo zolemera, tinthu tating'onoting'ono, ma virus ofooka, ndi zina zotere) zomwe zalowa m'thupi la munthu.

Mphamvu ya Titoctacid ndikuchotsa zotsatira za kuledzera mwachangu chifukwa chofulumizitsa kuchotsera komanso kusakhazikika kwa zinthu zomwe zimayambitsa poizoni m'thupi.

Kuchita ngati Tulinctacid monga insulini ndikochepetsa mphamvu ya shuga m'magazi mwakuwonjezera kudya kwake ndi maselo. Chifukwa chake, mwa anthu omwe ali ndi matenda ashuga, thioctacid imachepetsa kuchuluka kwa shuga m'magazi, imasintha matendawa ndipo imagwira ntchito m'malo mwa yake insulin. Komabe, zomwe amachita sizokwanira kuthana ndi insulin yakeyomwe, motero ndi matenda ashuga, muyenera kumwa mapiritsi omwe amachepetsa shuga, kapena jekeseni insulin. Komabe, mukamagwiritsa ntchito Thioctacid, mutha kuchepetsa kwambiri kuchuluka kwa mapiritsi kapena insulini kuti musunge shuga wambiri m'magazi ovomerezeka.

Thioctacid ali ndi hepatoprotective zotsatira ndipo angagwiritsidwe ntchito ngati gawo la zovuta kuchiza matenda osiyanasiyana a chiwindi, monga hepatitis, cirrhosis, etc. Kuphatikiza apo, mafuta owopsa amtundu wa asidi (lipotroteins yotsika kwambiri komanso yotsika kwambiri) omwe amachititsa kuti chitukuko cha atherosulinosis, IHD ndi ena matenda a mtima dongosolo. Kuchepa kwa kuchuluka kwa mafuta "owopsa" kumatchedwa hypolipidemic zotsatira za Thioctacid. Chifukwa cha izi, atherosulinosis imalepheretseka. Kuphatikiza apo, thioctacid imachepetsa njala, imaphwanya ma deposits a mafuta ndikulepheretsa zatsopano kudziunjikira, zomwe zimagwiritsidwa ntchito bwino kuchepetsa mafuta.

Zizindikiro zogwiritsidwa ntchito

Chizindikiro chachikulu chogwiritsa ntchito Thioctacid ndi chithandizo cha zizindikiro za neuropathy kapena polyneuropathy mu shuga mellitus kapena uchidakwa.

Kuphatikiza apo, Thioctacid akuwonetsedwa kuti agwiritse ntchito ngati gawo la zovuta pazochita zotsatirazi kapena matenda:

• Matenda a ziwiya zosiyanasiyana zamatumbo, kuphatikizapo
• Matenda a chiwindi (hepatitis ndi cirrhosis),
• Poizoni ndi mchere wazitsulo zolemera ndi zinthu zina (ngakhale grebe yoyera).

Solution Thioctacid 600 T - malangizo ogwiritsira ntchito

Woopsa matendawa ndi zizindikiro zazikulu za neuropathy, tikulimbikitsidwa kuti mankhwalawa ayenera kuperekedwa kwa masabata awiri mpaka 4, kenako ndikusintha kukonzanso kwa Thioctacid kwa nthawi yayitali pa 600 mg patsiku. Njira yothetsera vutoli imaperekedwa mwachindunji, kudzera pang'onopang'ono, kapena kugwiritsidwa ntchito kukonzekera yankho la kulowetsedwa kwa mtsempha. Kuti izi zitheke, zomwe zili mgulu limodzi ziyenera kuchepetsedwa mu kuchuluka kulikonse (mwina kuchepera) kwamchere wamankhwala. Pokhapokha utoto wa mchere ndi womwe ungagwiritsidwe ntchito pochotsa.

Mu neuropathy yayikulu, Thioctacid imayendetsedwa kudzera mu mawonekedwe a njira yokonzekera yopangidwa ndi 600 mg patsiku kwa masabata awiri mpaka anayi. Kenako munthu amamuthandiza kukonzanso Mlingo - 600 mg wa Thioctacid BV patsiku monga mapiritsi. Kutalika kwa mankhwalawa sikungokhala, ndipo zimatengera kuchuluka kwa kusintha komanso kutha kwa zizindikiro, kuchotsedwa kwa zinthu zowonongeka. Ngati munthu alandira infusions wa Thioctacid mu chipatala tsiku, ndiye kumapeto kwa sabata mungathe kusintha kwa mtsempha wa magazi mankhwala mapiritsi yemweyo mlingo.

Malamulo akukhazikitsa yankho la Thioctacid

Tsiku lililonse mlingo wa mankhwalawa uyenera kuperekedwa limodzi kulowetsedwa. Izi zikutanthauza kuti ngati munthu akufuna kulandira 600 mg wa Thioctacid, ndiye kuti gawo limodzi la kuchuluka kwa 24 ml liyenera kuchepetsedwa mu kuchuluka konse kwa saline yakuthupi, ndikuvulaza kuchuluka konse komwe kumapezeka panthawi. Kulowetsedwa kwa yankho la Thioctacid kumachitika pang'onopang'ono, mwachangu kwambiri kuposa mphindi 12. Nthawi yoyang'anira imadalira kuchuluka kwa thupi. yankho. Ndiye kuti, 250 ml ya yankho liyenera kuperekedwa mkati mwa mphindi 30 mpaka 40.

Ngati thioctacid imayendetsedwa ngati jakisoni wamkati, ndiye kuti yankho kuchokera pamwambalo limakokedwa mu syringe ndipo umayikiridwira umunthu wake. Intravenous makonzedwe amayenera kukhala osakwiya komanso otsiriza mphindi 12 kwa 24 ml ya mtima.

Popeza yankho la Thioctacid limakhudzidwa ndi kuwala, liyenera kukonzedwa nthawi yomweyo lisanayambike. Ma Ampoules omwe amakhala ndi chidwi amafunikanso kuchotsedwa pokhapira pokhapokha asanagwiritse ntchito. Munthawi yonse ya kulowetsedwa, kuti tipewe zoyipa zamagetsi pazotsirizidwa, ndikofunikira kuphimba chidebe chomwe chili ndi zojambulazo. Njira yotsirizidwa mumtsuko wokutidwa ndi zojambulazo imatha kusungidwa kwa maola 6.

Mimba komanso kuyamwa

Tsoka ilo, zomwe ophunzira adachita pompopompo komanso zotsatira za kuunika kwa mankhwalawa kwa Thioctacid sizimalola kutsimikiza kosatsimikiza za chitetezo cha mankhwalawa amayi apakati ndi amayi oyamwitsa. Palibe deta yotsimikizika komanso yotsimikizika pazokhudza Thioctacid pakukula ndi kukula kwa mwana wosabadwayo, komanso momwe amalowerera mkaka wa m'mawere. Komabe, mankhwala othandizira Thioctacid ndi otetezeka komanso osavulaza kwa anthu onse, kuphatikiza amayi oyembekezera.

Koma chifukwa chosowa deta yotsimikizika pachitetezo cha mankhwalawa, sayenera kugwiritsidwa ntchito panthawi yonse yomwe ali ndi pakati. Amayi oyembekezera amaloledwa kugwiritsa ntchito Thioctacid moyang'aniridwa ndikuyang'aniridwa ndi dokotala pokhapokha ngati phindu lomwe lingapezeke likuposa zoopsa zilizonse zomwe zingachitike. Mukamagwiritsa ntchito Thioctacid ndi amayi oyamwitsa, mwana ayenera kusamutsidwa kukhala zosakanikirana zochita kupanga.

Zochita Zamankhwala

Thioctacid imachepetsa mphamvu ya Cisplastine, chifukwa chake, pogwiritsa ntchito munthawi yomweyo, Mlingo wotsiriza uyenera kuchuluka.

Thioctacid imalowa mu kulumikizana kwa mankhwala ndi zitsulo, chifukwa chake singagwiritsidwe ntchito nthawi imodzi ndi kukonzekera komwe kumakhala ndi chitsulo, magnesium, calcium, aluminium, etc. Ndikofunikira kugawa kudya kwa Thioctacid ndikukonzekera komwe kumakhala ndi zitsulo kwa maola 4 - 5. Ndizabwino kwambiri kutenga Thioctacid m'mawa, ndikukonzekera ndi zitsulo - masanawa kapena madzulo.

Thioctacid imathandizira mphamvu ya insulin ndi mankhwala omwe amachepetsa shuga ya magazi (lipid-kuchepetsa mankhwala), chifukwa chake, mlingo wawo ungafunikire kuchepetsedwa.

Zakumwa zoledzeretsa zimachepetsa mphamvu ya thioctacid.

Thioctacid sigwirizana ndi mayankho a shuga (glucose, fructose, Ringer, etc.).

Mothandizidwa

Njira yothetsera ya thioctic acid imayendetsedwa mu mlingo wa 600 mg tsiku lililonse kwa masiku 14 mpaka 30. Mwina pang'onopang'ono mtsempha wowonjezera wa fomu yomalizira kapena pokonza njira yothetsera mtsempha wamkati. Mlingo wa tsiku ndi tsiku amaperekedwa limodzi ndi kulowetsedwa. Kulowetsa zinthu zosavomerezeka kuyenera kukhala pafupifupi mphindi 12. Nthawi yoyendetsa madontho amatengera kuchuluka kwa saline ndipo ayenera kukhala osachepera theka la ola kwa 250 ml.

A Alpha lipoic acid amamvera kuwala. Njira yothetsera makonzedwe yakonzedwa musanayambe kugwiritsidwa ntchito, chotengera chakecho chimayenera kukulunga ndi zojambulazo nthawi yonse ya kulowetsedwa, kuti kuwala kusalowe mumadzi okonzeka. Alumali moyo wa yankho lotere mumalo opanda mphamvu ndi maola 6. Mothandizidwa ndi mtsempha wa intrate, ampoule amachotsedwa phukusi lokha jakisoni.

Mapiritsi a Thioctacid

Fomu ya piritsi imafunikira kumwa mankhwalawa pamimba yopanda mphindi 30 musanadye chakudya cham'mawa. Piritsi liyenera kumeza lonse ndi madzi osachepera 125 ml. Sizingathe kutafunidwa, kugawidwa m'magawo kapena kuphwanyika. Mlingo wa tsiku ndi tsiku umatengedwa 1 nthawi. Maphunzirowa adapangidwa kuti agwiritse ntchito kwa nthawi yayitali (osachepera 1-2 miyezi), popeza chinthu chomwe sichichita chimakhala ndi ziwalo zathupi. Ndikothekanso kuyambiranso maphunzirowa (mpaka kanayi pachaka) mutakambirana ndi adokotala.

Migwirizano yogulitsa ndikusunga

Mankhwalawa amaperekedwa ndi mankhwala kuchokera kwa dokotala. Pogula, muyenera kulabadira kutsatira malamulo osungira mankhwalawo ndi moyo wake wa alumali. Njira yothetsera vutoli ndi mapiritsi ziyenera kusungidwa m'malo abwinobwino pa kutentha osaposa 25 ° C. Ayenera kutetezedwa kwa ana ndikupewa dzuwa. Alumali moyo wa mapiritsi ndi zaka 5, yokhazikika yankho - zaka 4.

Mankhwala otsatirawa atha kuonedwa ngati ma analogues a kachitidwe:

• Berlition - ili ndi chinthu chomwechi, koma chokhala m'misasa yochepa,
• Oktolipen - ali ndi mtengo wotsika, koma, malinga ndi odwala, pali zotsatira zoyipa zambiri,
• Tialepta, Thiolipon, Neuroleepone - mapiritsi opangidwa ku Ukraine omwe ali ndi bioavailability wotsika komanso mndandanda wazovuta (amalembedwa motsutsana ndi matenda ashuga a polyneuropathy).

Mtengo wa Thioctacid

Mutha kugula mapiritsi ndi kukhazikika m'masitolo ogulitsa mankhwala ku intaneti ku Moscow pamitengo zotsatirazi:

Yankho la jakisoni

Mtengo uliwonse wa 30 ma PC, ma ruble

Mtengo pa paketi ya 100 ma PC, ma ruble

Chiwerengero cha ampoules, ma PC

Olga, Thioctacid wazaka 23 adafotokozedwa ngati gawo limodzi la chithandizo chokwanira cha bambo anga kuchokera ku chiwindi cha chiwindi, chomwe chidayamba pamaso pake motsutsana ndi uchidakwa. Maphunzirowa atatha, chiwindi chimamuvutitsa, zonse zimakhazikika. Tikukhulupirira kuti kuyang'anira mobwerezabwereza kumathandizira kwambiri ndipo kupita patsogolo kudzakulitsa, ndipo zotsatira zake zidzaphatikizidwa.

Aleksey, wazaka 45 ndikutenga Thioctacid kuti muchepetse kukokana kwa miyendo komanso zizindikiro za polyneuropathy zomwe zimandivutitsa chifukwa cha matenda ashuga. Ndakhala ndikumwa mankhwalawa m'mapiritsi zaka zingapo, m'maphunziro. Ndimatenga masiku 14 kawiri pa tsiku komanso mwezi wina m'mawa. Pambuyo pake, wina akumva bwino, kutsekemera kwa glucose kumachepa, ndipo miyendo siyikhudzidwa.

Anastasia, wazaka 40 Kuzindikira kwanga - hepatitis - kumafuna kuchiritsika mosalekeza. Posachedwa, dokotala wandisankhira Thioctacid wokhala ndi Maksar kuteteza maselo a chiwindi. Pambuyo pa chithandizo, ndimamvanso bwino; ndikhululukidwa. Ndikhulupirira kuti kusankhidwa kwa chiwembuchi ndikusintha m'mbiri yanga ya zamankhwala, chifukwa asadakhalepo kanthu kosakhalitsa.

Svetlana, wazaka 50. Kuledzera kwa mwamuna wake kunapangitsa kuti miyendo yake iyambe kuchotsedwa, adati "ndi thonje". Dokotala wakuchipatala adamupangira ndondomeko yovomerezeka, yomwe idaphatikizapo Thioctacid. Maphunziro omwe adamwa adapereka zotsatira zabwino - patatha milungu ingapo adasiya kudandaula za mapazi ake. Pansi pake pali mtengo wake wokwera. Koma zimathandizadi.

Zotsatira zoyipa za Thioctacid

Zodziwika pang'onopang'ono ndi mapiritsi a Thioctacid ndizotsatira zoyipa, zomwe ndi zizindikiro zomwe zimayamba chifukwa cha kuchepa kwa shuga m'magazi, monga chizungulire, mseru, thukuta kwambiri, kupweteka kwa mutu komanso kuwona kawiri.

Thioctacid Yang'anirani zitha kuyambitsa zotsatirazi zosiyanasiyana kuchokera ku ziwalo ndi machitidwe osiyanasiyana:
1.Kuchokera ku dongosolo lamanjenje lalikulu:

• Zingwe
• Masomphenya apawiri (diplopia)
• Ngati mankhwalawa amaperekedwa mwachangu kwambiri, kuwonjezeka kwa kuthamanga kwa magazi, kumva kuthamanga kwa magazi kumutu, ndi kupuma komwe, komwe kumadutsa palokha ndipo sikufuna chithandizo kapena kuthetsedwa kwa thioctacide, ndikotheka.

• Zikhungu pakhungu,
• Urticaria,
• Kuyabwa
• Anaphylactic mantha,
• Eczema
• Kuchepa kwa khungu.

• Malo ochepa akhungu pakhungu kapena mucous nembanemba (petechiae),
• Kuthetsa magazi
• Kuchepa kwa mapulozi,
• Pumbwa
• Thrombophlebitis.

• Kuchepetsa mseru
• Kubweza
• Kuphwanya kukoma (kukoma kwazitsulo mkamwa).

Mapiritsi a Thioctacid zingayambitse zotsatirazi:

• Kuchepetsa mseru
• Kubweza
• Kupweteka kwam'mimba
• Kutsegula m'mimba
• Zotupa pakhungu
• Urticaria,
• Kuyabwa
• Anaphylactic mantha,
• Kusintha kwamakomedwe
• Chizungulire
• Jaundice

Thioctacid (BV, 600) - analogies

Pakadali pano pali zokonzekera zomwe zimakhala ndi thioctic acid pamsika wamankhwala amayiko, koma sizofanana ndi Thiotacid, popeza ali ndi mtundu wina wamasulidwe ndipo, chifukwa chake, kutayika kwa chinthu chogwira ntchito, kuchepa kwa m'mimba.Kuphatikiza apo, kuti muchepetse mtengo wa ma CD, mapiritsi ochepa okhala ndi mapiritsi ochepa alipo, ndipo chifukwa chake, njira yochepetsetsa ya chithandizo - miyezi itatu - imakhala yodula kwambiri, makamaka ngati phwando lakhala lalitali, kupitilira chaka. Zotsatira zakuchiritsira zamankhwala wamba sizinafanane ndi thioctacid; "Ma analogues" ena amadzisintha ngati mankhwala opangidwa ku Europe, koma chinthu chomwe chikugwiridwacho chagulidwa ku China, zinthu za ballast zimawonjezeredwa, chifukwa chake muyenera kusamala kwambiri ndizomwe zili phukusili.