Antibiotic flemoklav solutab: malangizo, ntchito, ndemanga, mtengo

Nkhaniyi ndi ya zidziwitso zokhazokha. Musanagwiritse ntchito mankhwalawa, ndikulimbikitsidwa kufunsa dokotala.

Flemoklav solutab ndi anti-penicillin wokhala ndi zochita zambiri. Imawononga tizilombo tating'onoting'ono tating'onoting'ono, tokhala pamakoma a maselo awo. Muli clavulanic acid, yomwe imatha kulepheretsa ntchito ya mabakiteriya a beta-lactamase, kuwapanga kukhala pachiwopsezo cha antiotic.

Kenako, tikambirana mwatsatanetsatane flemoklav solyutab. Malangizo ogwiritsira ntchito, mtengo, ndemanga, analogi - zonse zofunika kwambiri za mankhwalawa m'nkhaniyi.

Mukawerenga nkhaniyi, muphunzira kuti:

Momwe mungatenge flemoklav.
Kuli kuti ndibwino kugula.
Kodi maantibayotiki amagwira ntchito bwanji?
Momwe mungasinthire flemoklav.
Kwa iye yemwe adaphatikizidwa.
Zomwe amachiritsa.
Zomwe zili mukuphatikiza.
Zotsatira zoyipa zomwe zingachitike.

Malangizo ogwiritsira ntchito antibayotiki

Malangizo ogwiritsira ntchito mankhwala a flemoklav solyutab gawo ndi gawo akukuuzani momwe mungamwe mankhwalawa.

Imwani piritsi musanadye.
Swallow lonse, kumwa madzi ambiri, kapena kusungunuka theka la kapu yamadzi, yambitsa mosamala musanatenge.
Kwa ana a zaka 12 ndi akulu, flemoclave nthawi zambiri amawayika pa mlingo wa 500 mg / 125 mg katatu patsiku, nthawi yayitali pakati pa Mlingo uyenera kukhala osachepera maola 8.
Kwa ana a zaka 7 mpaka 12 - pa mlingo wa 250 mg / 62,5 mg katatu pa tsiku.
Kwa ana ochepera zaka 12, mlingo watsiku ndi tsiku amawerengedwa molingana ndi kulemera kwa matendawa, kutengera mphamvu ya matendawa, kuyambira 20 mg / 5 mg mpaka 60 mg / 15 mg wa amoxicillin / clavulanic acid pa kilogalamu ya thupi. Mlingo wa tsiku ndi tsiku umagawidwa katatu.
Ana a zaka 2 mpaka 7 zotchulidwa mlingo wa 125 mg / 31.25 mg katatu patsiku.
Mu matenda oopsa, mlingo ndi wovomerezeka.
Mlingo wokwanira sayenera kupitirira 60 mg / 15 mg ya amoxicillin / clavulanic acid pa kilogalamu ya thupi.
Njira ya mankhwalawa imatengera kuopsa kwa matendawa ndipo osapitilira masiku 14.

Ndi malo ati omwe amapezeka bwino kugula + mtengo

Flemoklav imapezeka popanda mankhwala mumasitolo ogulitsa kapena pa intaneti, nayi ena a iwo:

Rigla - Imapatsa makasitomala ake ufulu wolandila kuchotsera pamakhadi ochezera.
Thandizo Loyamba ndi Utawaleza - mitengo yapadera ndi kuchotsera pazakukonzekera ndi nyengo.
Mankhwala.ru - phukusi la mapiritsi 20 okhala ndi mulingo wa 500 mg / 125 mg umawononga 403 rubles.

Mtengo wa flemoklav umadalira mlingo wa yogwira:

Flemoklav 125 mg - kuchokera 290 p.
Flemoklav 250 mg - 390-440 p.
Flemoklav 500 mg - 350-430 p.
Flemoklav 875 mg - kuchokera 403 p.

Ndemanga

Flemoklav solutab amaphatikiza zigawo ziwiri zikuluzikulu, chilichonse chimagwira ntchito yake.
Amoxicillin - kapangidwe kake kamene kamakhala ndi mankhwala osokoneza bongo omwe amagwiritsidwa ntchito motsutsana ndi tizilombo tambiri. Koma imatha kuwonongeka chifukwa cha beta-lactamases, chifukwa chake zotsatira za amoxicillin sizikugwira ntchito pazinthu zazing'onoting'ono zomwe zimapanga enzyme iyi.

Clavulanic acid amagwira pamakoma a mabakiteriya opanga beta-lactamases, potero amateteza amoxicillin kuti asawonongeke ndi ma enzyme.

Zomwe zimathandiza

Mankhwala ntchito mankhwalawa matenda:

m'munsi komanso kumtunda kwa kupumira
Ziwalo za ENT,
Matenda amtunduwu
khungu ndi minofu yofewa,
kupewa matenda opaleshoni.

Madokotala amafufuza

Ndemanga za madokotala za flemoklava zikuwonetsa kukhathamira ndi kuyambika kwakanthawi kogwiritsiridwa ntchito kwa mankhwalawa.

Mankhwala abwino okhala ndi mawonekedwe osiyanasiyana a gulu la penicillin. Amagwira motsutsana ndi aerobic ndi anaerobic gram-positive ndi gram-negative bacteria. Nthawi zonse ndimapereka mankhwala ochotsera zovuta, koma nthawi zonse ndimatsutsana ndi kukonzekera komwe kumakhala ndi mabakiteriya a lactic acid. Zachidziwikire, chilichonse ndimunthu payekha.

Ndimagwiritsa ntchito lymphadenitis yamitundu yambiri. Ndikugawira Flemoklav 875/125 ku 1 tabu. 2 pa tsiku kwa masiku 7. Pakatha masiku 7, palibe njira zokulira zotsalira zomwe zimatsala. Kuphatikiza ndi chithandizo chakomweko. Mwambiri, odwala ndimakhutira ndi mankhwalawa.

Ubwino wosakayikira wa mankhwalawa ndikuti ndizotheka kuutenga mu mawonekedwe osungunuka. Chimafanana ndi madzi otsekemera, ndipo ndi oyenera kumwa ana. Ubwino waukulu pamankhwala ena opha maantibayotiki ndikuti samayambitsa zotsatira zoyipa monga dysbiosis.

Ndemanga za anthu

Pansipa pali ndemanga zochepa chabe mwa ambiri komanso osiyanasiyana omwe amachititsa odwala za mankhwalawo.

Anandiuza kuti akhale dokotala wa opaleshoni nditalowetsa dzino. Zowona piritsi limodzi 2 kawiri pa tsiku kwa masiku 7. Sindinazindikire chilichonse chokhudzana ndi kumwa mankhwalawo. Ngakhale malangizo adalembedwa zambiri zomwe zimapangitsa kuti thupi lizisintha, monga mseru. Ichi ndi mankhwala amphamvu. Adandithandiza, chilichonse chidachira mwangwiro. Chitetezo chokwanira chidagwa ndipo matumbo ake adachepa.

Ndinakhala ndikugwiritsidwa ntchito ndi flemoklav kangapo, popeza ndakhala ndikudwala matenda opha ziwalo kwa zaka zoposa zisanu. Zachidziwikire, tsopano ndimayesetsa kuti ndisathamangire pamalo ozama, pomwe maantibayotiki okha amathandiza, koma nthawi zina zimachitika. Imalimbana bwino ndi bronchitis. Pali m'modzi “koma.” Ndi mankhwala amphamvu kwambiri, motero amapatsanso zovuta zina ziwalo zina. Nditamwa mankhwalawa, ndidamva ululu m'matumbo ndi impso. Kenako ndinayenera kutenga zofunikira ndi linex kuti ndichiritse.

Mwana wanga "Flemoksiklav solutab" adalembedwa ndi dokotala wakuchipatala. Adazindikira kuti mwana ali ndi vuto. Kutentha pa madigiri 40 sikunasokere konse. Pambuyo pakuyamba kwa mankhwalawa, kutentha kunatsitsidwa mpaka madigiri 39, tsiku lachiwiri linagwa mpaka madigiri 37. Ndipo tsiku lachitatu malungo adadutsa ndipo kuyimilira koyera kudatuluka. Tinamwa kwathunthu masiku 7. Khosi, komabe, linapitilirabe kuthandizidwa ngakhale atamwa maantibayotiki. Kuchira kwathunthu kunabwera patatha masiku 10. Dotoloyo akuti kuyambiranso kumachitika, ndipo zilonda zapakhosi zidzabwezeranso, koma zonse zidapita popanda zovuta zapadera.

Dokotala wathu wa ana nthawi zonse amatipatsa mankhwalawa kwa ife kuzizira. Adanenanso kuti pa maantibayotiki onse, amalekeredwa bwino ndi ana ndipo palibe mavuto. Ndimagwirizana naye kwathunthu. Ana anga amanyamula popanda mavuto.

Pansipa pali ndemanga yaying'ono yamankhwala.

Flemoklav solutab adalembedwa matenda osiyanasiyana opatsirana, pakati pawo:

Matenda opumira kwambiri a m'mapapo. Matenda amenewa akuphatikizira matenda amkhutu, mphuno ndi mmero, kuphatikizira matendawa (kutupa kwamatumbo), pharyngitis (kutupa kwa pharynx), kutupa kwa khutu lapakati (otitis media), sinusitis ndi frontal sinusitis. Zambiri mwa ma pathologies amenewa zimagwirizanitsidwa ndi matenda a streptococci, hemophilic bacillus, moraxella, streptococcus. Izi zikufotokozera mphamvu ya mankhwalawa mu purulent, lacunar ndi bacterillion tonsillitis.
Matenda ochepetsa kupuma thirakitindiko, bronchitis ndi chibayo, chomwe chibayo streptococcus, hemophilus bacillus ndi moraxella nthawi zambiri amakhala ndi vuto.
Matenda a urogenital thirakitikuphatikiza cystitis (kutupa kwa chikhodzodzo), matenda otupa a urethra (urethritis), impso (pyelonephritis), matenda ena opatsirana a m'matumbo obwera chifukwa cha mabakiteriya omwe amakhala ndi chidwi cha flemoclave (staphylococci kapena enterococci). Kuphatikiza apo, amoxicillin wokhala ndi clavulanic acid awonetsedwa kuti amagwira ntchito m'njira yovuta kwambiri ya chinzonono, koma sizikutanthauza konse kuti odwala atha kuyamba mankhwala othandizira okha popanda thandizo la katswiri.
Khungu ndi matenda ofewa a minofu (erysipelas, abscesses ndi zina). Izi pathologies nthawi zambiri zimayamba chifukwa cha Staphylococcus aureus, streptococcus ndi bacteroids omwe amamva flemoklava.
Mafupa ndi mafupa olowa. Osteomyelitis, yomwe nthawi zambiri imayamba chifukwa cha matenda a Staphylococcus aureus. Malangizo a akulu ndi ana akutsindika kuti ndi osteomyelitis ndizovomerezeka kuchitira mankhwalawa nthawi yayitali.
Matenda opatsirana a mano. Periodontitis, maxillary odontogenic sinusitis yolumikizidwa ndi matenda amano mu minyewa ya nsagwada yapamwamba ndi zina zotero.
Matenda ena opatsirana. Postpartum sepsis (poyizoni wamagazi) ndi matenda ena oopsa (monga mbali ya zovuta mankhwala a antibayotiki).

Contraindication

Flemoklav sanalembedwe kwa odwala:

Ndi tsankho la munthu la amoxicillin, mankhwala a clavulanic acid ndi beta-lactam (kuphatikizapo penicillin ndi cephalosporins).
Ndi matenda am'mimba, limodzi ndi matenda am'mimba komanso kusanza.
Odwala omwe adayamba kukanika kwa chiwindi ndi kugwiritsidwa ntchito kale kwa clavulanic acid kapena amoxicillin.
Mankhwala ali osavomerezeka zochizira ana masekeli zosakwana 13 makilogalamu.
Flemoklav imaphatikizidwa mu matenda opatsirana a mononucleosis ndi lymphocytic leukemia.

Gwiritsani ntchito mosamala poyendetsa galimoto ndikugwiritsa ntchito makina owopsa.

Zotsatira zoyipa

Mukatenga flemoklav, zotsatirazi zotsatirazi zingachitike:

Mitsempha yamkati yotupa: kupweteka, kupweteka mutu, chizungulire (ndi mankhwala osokoneza bongo kapena kuwonongeka kwa impso), nthawi zina nkhawa, kuda nkhawa, kuchita zinthu mwamtopola, kusowa tulo, kuchepa mphamvu, kusokonezeka kwa chikumbumtima.
Dongosolo la Hematopoietic: kawirikawiri hemolytic anemia, thrombocytosis, nthawi zina magazi, leukopenia, thrombocytopenia, granulocytopenia, pancytopenia (zotsatirazi zimatha kusintha ndikusowa mankhwala atatha.
Matenda a mtima: kawirikawiri - vasculitis.
Dongosolo la genitourinary: kawirikawiri - kuwotcha, kuyabwa, kumeta, maliseche nephritis.
Makina othandizira: nthawi zina - kuwonjezeka kwa magazi nthawi ndi prothrombin nthawi.
Chiwindi: kuwonjezeka pang'ono pa ntchito ya michere ya chiwindi, kawirikawiri - cholestatic jaundice ndi hepatitis.
Matumbo: kunyansidwa (kumachitika ndi mankhwala osokoneza bongo), kupweteka kwam'mimba, kusanza, kutsegula m'mimba, kusakhalitsa, pseudomembranous colitis (wolimbikira komanso kutsegula m'mimba kwambiri chifukwa cha mankhwala kapena kwa masabata asanu atatha kumapeto kwa chithandizo).
Mawonekedwe a mziwi: pachimake ngati exanthema yomwe imachitika tsiku la 5 mpaka 11 atayamba kumwa mankhwala, zotupa pakhungu ndi kuyabwa.
Zina: fungal kapena bakiteriya wamphamvu (wokhala ndi chithandizo chokhalitsa kapena maphunziro achiwerewere).

Bongo

Mankhwala osokoneza bongo a Flemoclave ndi osowa. Nthawi zambiri izi zimachitika mosemphana ndi malamulo a kumwa maantibayotiki. Zizindikiro Zambiri:

nseru
kutsegula m'mimba
kusanza
kuledzera thupi
kukokana
matenda a hemolytic, kulephera kwa impso, acidosis, crystalluria, vuto ladzidzidzi limachitika kawirikawiri.

Chochita choyamba ngati bongo chikuyenera kupweteka. Kuti athane ndi vuto la bongo, wodwalayo ayenera kumwa makala opaleshoni. Ndikofunika kusungitsa electrolyte ndi madzi moyenera.

Mapiritsi a Flemoclave amaphatikiza zigawo ziwiri zazikulu:

Amaperekedwa ndi mitundu yosiyanasiyana ntchito:

Mankhwala ochepetsa mphamvu a m'badwo watsopano amatsogola kwambiri pakulimbana ndi matenda oyambitsidwa ndi bakiteriya, koma nthawi zina, odwala amafunika kusintha mankhwalawo ndi analogue yapamwamba. Zomwe zimayambitsa zimatha kukhala zosalolera pazinthu zomwe zimapangidwira, chidwi cha mabakiteriya osokoneza bongo, kusowa kwa mankhwala kapena mtengo wokwera.

Zosangalatsa. Odwala ndi tsankho kwa zigawo zikuluzikulu za flemoklav solutab. The yogwira pophika mankhwala ndi azithromycin dihydrate. Mtengo 400-600 rub.
Wilprafen. Chogulacho chimapezeka ngati mapiritsi osungunuka, koma tanthauzo lake ndi josamycin. Ndikosatheka kudziwa kuti ndi mankhwala ati omwe ali othandiza komanso othandiza, vilprafen kapena flemoklav. Mtengo 450-650 rub.
Zinnat. Amatengera mankhwala osankha achiwiri, amawonetsedwa akalandira mankhwala a antibayotiki m'miyezi iwiri yapitayo, komanso matenda a nosocomial akapezeka. Ili ndi mphamvu kwambiri kuposa flemoklav. Mtengo wa ma ruble a 150-250.
Klacid. Mankhwala apakhomo, otsika mtengo komanso amphamvu kuposa mankhwala flemoklav. Imapezeka mu njira yothetsera kuyimitsidwa koyima kwa kuyimitsidwa, odwala amawona kukoma kwake kosasangalatsa. Mtengo 200-300 rub.

DZIFUFUZO: Mafunso Ofunsidwa Kawirikawiri

Flemoklav pa nthawi yapakati?

1 trimester. Kugwiritsa ntchito flemoklav ndikosayenera. Miyezi yoyambirira ya bere ndi nthawi yoopsa kwambiri pankhani ya kugwiritsa ntchito mankhwala, makamaka maantibayotiki. Mwana wosabadwayo satetezedwa, ziwalo zake zikukula mwachangu, ndipo kulowerera kwa zinthu zakuthambo kungavulaze mwana. Ngati, mukuganiza za dotolo, simungathe kuchita popanda mankhwala othandizira, tengani mosamala ndi kuyang'aniridwa ndi adokotala mosamala kwambiri.
2 trimester. Mankhwala ndikuwunikira pakugwiritsa ntchito flemoklav amakhalabe ofunikira kwambiri pakumwa mankhwala a antiquapter wachiwiri.
3 trimester. Nthawi yotetezeka kwambiri ya kumwa maantibayotiki, yodziwika ngati ali pachipatala chovomerezeka. Koma adotolo amawerengetsa, dokotala amawongolera mankhwalawo, dokotala amawunika momwe wodwalayo alili. Mankhwala omwe amadzilimbitsa thupi samachotsedwa panthawi iliyonse yomwe mayi ali ndi pakati.

Kodi flemoklav imagwirizana ndi mowa?

Monga momwe amachitira mankhwala ena aliwonse a antibayotiki, mowa umapangidwa pakumwa flemoklav. Imfa yakugwiritsidwa ntchito munthawi yomweyo simatha, koma ziwalo zina zimatha kulimbikitsidwa kwambiri.

Kodi flemoklav ndalama zingati?

Mtengo wa flemoklav umadalira mlingo wa yogwira:

Kutulutsa mafomu ndi kapangidwe kake

Flemoslav imapezeka mu mawonekedwe a mapiritsi omwazika (amasungunuka mkamwa ndipo safuna kumeza) pakhungu lowala (loyera mpaka lachikasu). Mitengo ya brown imakhalapo nthawi zina.

Kugwiritsa ntchito kwa mankhwala ndi chifukwa cha kapangidwe kake:

amoxicillin 500 mg - penicillin opanga maantibayotiki omwe ali ndi mphamvu zambiri pamagulu osiyanasiyana a tizilombo toyambitsa matenda, tizilombo ta matenda ndi kuperewera,
clavulanic acid 125 mg - zoletsa, zoteteza ma enzymatic, zimakhala ndi antibacterial pamitundu ina ya ma bacteria a anaerobic,
microcrystalline cellulose - gawo lazomera, zomwe zimathandizira kagayidwe kazinthu,
kununkhira kwa apurikoti, vanillin - mamvekedwe ndi zowonjezera zonunkhira,
crospovidone bwino magazi, imagwira ntchito monga plasma m'malo mwa chitetezo chamthupi,
mchere wa magnesium (E572) - gawo lothandiza,
saccharin (E954) ndiwotsekemera.

Chotupacho chili ndi mapiritsi 4, pamakatoni a makatoni - matuza 5.

Chotupacho chili ndi mapiritsi 4, pamakatoni a makatoni - matuza 5. Phukusi lililonse lili ndi malangizo ogwiritsa ntchito, omwe muyenera kudziwa musanayambe kugwiritsa ntchito mapiritsi.

Pharmacokinetics

Mapiritsiwo amatengedwa chifukwa cha michere ya m'mimba. Ma inhibitors omwe amapanga mapiritsi opondereza beta-lactamases (ma enzymes omwe amalepheretsa zochita za antibayotiki). Kagayidwe kazinthu zazikulu zomwe zimagwira m'chiwindi. Amachotsa impso.

Kagayidwe kazigawo zikuluzikulu zimagwira m'chiwindi, zotulutsidwa ndi impso.

Zizindikiro zogwiritsidwa ntchito

Lembani mankhwalawa mu milandu iyi:

bakiteriya matenda am'mapapo thirakiti - laryngitis, tonsillitis, pharyngitis, bronchitis, chibayo, sinusitis, ndi zina zambiri.
pa matenda a pakhungu (abrasions, mabala, zilonda zam'mimba, abscess, erysipelas),
ndi poyizoni wamagazi, omwe amawonetsedwa ndi zithupsa, zilonda ndi zotupa
Chithandizo ndi kupewa matenda opaleshoni,
matenda opatsirana a genitourinary ndi kwamikodzo dongosolo - urethritis, cystitis, pyelonephritis, vaginitis, gonorrhea,
matenda osachiritsika a minofu yama cartilage (antibayotiki amatengedwa ndi zovuta mankhwala).

Bacteria matenda a kupuma thirakiti - laryngitis, tonsillitis, pharyngitis, bronchitis, chibayo, sinusitis, ndi chifukwa kukhazikitsidwa kwa mankhwala.
Flemoklav solutab amachiritsa mabala abwino
Mankhwalawa amatchulidwa pambuyo pa opareshoni.
Woopsa matenda a mafupa-cartilaginous, flemoklav solutab ndi mankhwala.

Flemoklav Solutab adalembedwa matenda osiyanasiyana omwe amayamba chifukwa cha anaerobic, gram-positive ndi gram-negative bacteria.

Momwe mungatenge Flemoklav Solutab 500?

Flemoklav - mapiritsi okhala ndi madzi, motero amasungunuka mkamwa ndikutsukidwa ndi madzi ambiri oyera (mkaka, mkaka, tiyi - pansi pa chiletso).

Mlingo umatengera mtundu wamatenda, zaka za wodwala komanso machitidwe a thupi.

Odwala akuluakulu omwe ali ndi angina, sinusitis, cystitis ndi matenda ena opatsirana amafunika kumwa piritsi limodzi la 500 mg (2 mg) kawiri pa tsiku. Nthawi zina adotolo amatha kulowetsamo mlingo ndi 1 mlingo mu 875 mg.

Masiku angati kuti amwe?

Njira ya mankhwalawa imatengera kuwonongeka kwake komanso momwe wodwalayo alili. Chithandizo chokwanira chimatenga masiku 7. Ngati ndi kotheka, maphunzirowa amawonjezedwa, koma Flemoklav Solutab sayenera kumwedwa kwa milungu yopitilira 2.

Flemoklav - mapiritsi okhala ndi madzi, motero amasungunuka mkamwa ndikutsukidwa ndi madzi oyera ambiri.

Hematopoietic ziwalo

Kuchulukitsa matupi oyera ndi ofiira am'magazi - maplateleti, maselo oyera am'magazi, maselo ofiira am'magazi, kuchepa kwa magazi, kutsika kwa kuchepa kwa matendawo. Nthawi zambiri, magazi amatuluka mkati.

Kupezeka kwa kutsekula m'mimba kapena kudzimbidwa kumayambitsidwa ndi vuto la m'mimba.

Kuchokera kwamikodzo dongosolo

Interstitial nephritis ndimatenda a impso otupa komanso kutulutsa kwina kwa ndere.

Thupi lawo siligwirizana kumachitika ndi mankhwala osokoneza kapena osokoneza mankhwala ena. Urticaria, kuyabwa, redness la khungu ndi chizindikiro cha kupsa mtima.

Thupi lawo siligwirizana kumachitika ndi mankhwala osokoneza kapena osokoneza mankhwala ena.

Zokhudza mphamvu pakuwongolera njira

Phunziroli silinawonetsetse zoyipa zilizonse zomwe zingakhale choletsa kuyendetsa galimoto. Kupatula ndiko kusokonezeka kwamanjenje, komwe kumayambitsa kugona kapena kukwiya.

Phunziroli silinawonetsetse zoyipa zilizonse zomwe zingakhale choletsa kuyendetsa galimoto.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Mu trimester yoyamba, mankhwala othandizira ayenera kutayidwa, chifukwa zimatha kuyambitsa kusokonezeka kapena kuchedwa kwa chitukuko cha fetal. Pa trimesters ya II ndi III, Flemoklav imatha kutengedwa pokhapokha ngati dokotala watchulidwa, ngati zotsatira zomwe zikuyembekezeredwa zikupitilira chiwopsezo chomwe chitha. Kumwa maantibayotiki mukamakhala ndi vuto kumabweretsa mwana wosabadwa. Pa HB, mumafunikiranso kusiya maantibayotiki kapena kuwamwa mutatha kuwonongeka kuti mankhwalawa asalowe mkaka. Mlingo ndi 500 mg kamodzi patsiku.

Momwe mungapereke Flemoklav Solutab kwa ana 500?

Ngati pakufunika kuthandiza ana, mtundu wina wa mankhwalawa umaperekedwa ndi mlingo wotsika, mwachitsanzo, 125 mg.

Kugwiritsa ntchito kwa vuto la chiwindi

Kwa matenda a chiwindi, amoxicillin osavomerezeka. Mankhwala othandizira amangoperekedwa pokhapokha ngati pakufunika, mlingo umachepetsedwa.

Kwa matenda a chiwindi, amoxicillin osavomerezeka.

Kuchita ndi mankhwala ena

Allopurinol kuphatikiza ndi amoxicillin kumawonjezera chiopsezo cha ziwopsezo, zotupa pakhungu, kuyabwa. Ndikulimbikitsidwa kupewa mankhwalawa munthawi yomweyo (ndikofunikira kupewetsa maantibayotiki ndi omwe alibe amoxicillin).
Minyewa, glucosamine, ndi aminoglycosides amachepetsa kuyamwa kwa maantibayotiki.
Clavulanic acid imachepetsa mphamvu ya mapiritsi oteteza kubadwa ndipo imatha kuyambitsa kamvekedwe ka chiberekero, komwe kumayambitsa magazi ambiri otuluka.
Kuphatikiza ndi cephalosporins kumapangitsa kuti bactericidal ikhale.
Diuretics ndi Flemoklav (okodzetsa mankhwala) zimachulukitsa kuchuluka kwa amoxicillin m'thupi, zomwe zimatha kuyambitsa zovuta zingapo.

Clavulanic acid imachepetsa mphamvu ya mapiritsi oteteza kubadwa ndipo ingayambitse kamvekedwe ka chiberekero.

Pali mankhwala ambiri a analog omwe angalowe m'malo mwa Flemoklav popanda kupezeka kapena zotsutsana:

kutengera amoxicillin ndi clavulanic acid - Abiclav, Amoxiclav, Betaclav, Teraclav, Amoxicillin Trihydrate,
pa amoxicillin - Neo Amoxiclav,
ampicillin + sulbactam - Ampiside, Ampicillin, Sulbacin, Unazin,
Amoxicillin ndi Cloxacillin - Vampilox.

Flemoklav ikhoza kusinthidwa ngati palibe kapena ikuphatikizidwa ndi Amoxiclav.

N`zosatheka kugwiritsa ntchito fanizo nokha, kuyankhulana ndi adokotala ndikofunikira.

Njira yamachitidwe

Amoxicillin ndi mankhwala osokoneza bongo owoneka bwino ochulukirapo omwe ali ndi ntchito yolimbana ndi ma gram ambiri komanso gram alibe tizilombo. Nthawi yomweyo, amoxicillin amatha kuwonongedwa ndi beta-lactamases, chifukwa chake ntchito yokhala ndi amoxicillin sinafikira tizilombo tomwe timatulutsa timadzi tambiri. Clavulanic acid, beta-lactamase inhibitor yokhudzana ndi penicillin, amatha kuyambitsa mitundu yambiri ya beta-lactamases yomwe imapezeka mu penicillin ndi cephalosporin zosagwira tizilombo. Clavulanic acid ili ndi mphamvu yokwanira yolimbana ndi plasmid beta-lactamases, yomwe nthawi zambiri imatsimikiza kukana kwa mabakiteriya, ndipo sagwira ntchito motsutsana ndi mtundu wa 1 wa chromosomal beta-lactamases, womwe suletsedwa ndi clavulanic acid.

Kukhalapo kwa clavulanic acid mu Flemoklav Solutab kukonzekera kumateteza amoxicillin kuti asawonongedwe ndi ma enzyme - beta-lactamases, omwe amalola kukulitsa mawonekedwe a antibacterial a amoxicillin. Otsatirawa ndi ntchito ya vitro yosakanikirana ya amoxicillin yokhala ndi clavulanic acid.

Yogwira motsutsa mabakiteriya okhala ndi aerobic gram - kuphatikiza mabakiteriya opanga beta-lactamases: Staphylococcus aureus, aerobic gram-negative bacteria: Enterobacter spp., Escherichia coli, Haemophilus influenzae, Klebsiella spp., Moraxella catarrhalis. Tizilombo toyambitsa matenda totsatirayi timangokhala tokha mu vitro: Staphylococcus epidermidis, Streptococcus pyogene, Streptococcus anthracis, Streptococcus pneumoniae, Streptococcus viridans, Enterococcus faecalis, Corynebacterium spp. Listeria monocyicolis (kuphatikiza zingwe zopanga beta-lactamases): Proteus mirabilis, Proteus vulgaris, Salmonella spp., Shigella spp., Bordetella pertussis, Yersinia enterocolitica, Gardnerella vaginalis, Neisseria meningitidis, Neisseria gonorrhoeae, Haemophi libelee Campus jejuni, bakiteriya wa anaerobic gram-negative (kuphatikizapo beta-lactamase yopanga tizilombo ta): Bacteroides spp. Tiyi Bacteroides fragilis.

Kuphatikiza kwa amoxicillin ndi clavulanic acid akuwonetsedwa kuti azichiza matenda a bakiteriya a malo otsatirawa omwe amayamba chifukwa cha tizilombo tomwe timayang'ana pakuphatikizidwa kwa amoxicillin ndi clavulanic acid:

Matenda opumira kwambiri a m'mapapo (kuphatikizapo matenda a ENT), mwachitsanzo.
Matenda ochepetsa kupuma am'mimba, monga kufalikira kwa chifuwa cham'mimba, chibayo, ndi bronchopneumonia, omwe amayamba chifukwa cha Streptococcus pneumoniae, Haemophilus fuluwenza, ndi Moraxella catarrhalis.
Matenda a urogenital thirakiti, mwachitsanzo, cystitis, urethritis, pyelonephritis, matenda amtundu wamkazi, omwe nthawi zambiri amayamba chifukwa cha mitundu ya banja la Enterobacteriaceae (makamaka Escherichia coli), Staphylococcus saprophyticus ndi mitundu ya genus Enterococcus, komanso gonorrhea yoyambitsidwa ndi Neisseria gonorrhoeae.
Matenda a pakhungu ndi minofu yofewa, yomwe nthawi zambiri imayamba chifukwa cha Staphylococcus aureus, Streptococcus pyogene, ndi mitundu ya mtundu wa Bacteroides.
Kutupa kwa mafupa ndi mafupa, mwachitsanzo, osteomyelitis, yomwe nthawi zambiri imayamba chifukwa cha Staphylococcus aureus, ngati pakufunika kutero, chithandizo cha nthawi yayitali ndizotheka.
Matenda a Odontogenic, mwachitsanzo, periodontitis, odontogenic maxillary sinusitis, zotupa zamano kwambiri ndi kufalitsa kwa cellulitis.

Matenda ena osakanikirana (mwachitsanzo, kuchotsa mimba kwa septic, sepsis ya pambuyo pake, intra-m'mimba sepsis) monga gawo la njira yothandizira.

Matenda oyambitsidwa ndi tizilombo tating'onoting'ono ta amoxicillin amatha kuthandizidwa ndi Flemoklav Solutab, chifukwa amoxicillin ndi chimodzi mwazomwe zimagwira. Flemoklav Solutab amasonyezedwanso ntchito yochizira matenda osakanikirana oyambitsidwa ndi tizilombo tating'onoting'ono tokhala ndi amoxicillin, komanso ma tizilombo tating'onoting'ono timene timatulutsa beta-lactamase, tcheru ndi kuphatikiza kwa amoxicillin ndi clavulanic acid.

Mphamvu ya mabakiteriya kuphatikiza kwa amoxicillin ndi asidi wa clavulanic amasiyanasiyana malinga ndi dera komanso nthawi. Ngati kuli kotheka, zosowa zamderalo ziyenera kukumbukiridwa. Ngati ndi kotheka, zitsanzo za tizilombo ting'onoting'onoting'ono ziyenera kusungidwa ndikuwunikiridwa kuti mumve ma bacteria.

Mlingo ndi makonzedwe

Zokhudza pakamwa.

Mlingo wa mankhwalawa umayikidwa payekha kutengera zaka, kulemera kwa thupi, impso ya wodwalayo, komanso kuopsa kwa matendawa. Kuti muchepetse kusokonezeka kwa m'mimba ndikuwonjezera kuyamwa, mankhwalawa ayenera kumwedwa kumayambiriro kwa chakudya. Piritsi limamezedwa lonse, kutsukidwa ndi kapu ya madzi, kapena kusungunuka ndi theka kapu yamadzi (osachepera 30 ml), kuyambitsa bwino musanagwiritse ntchito. Njira yochepetsetsa ya mankhwala opha maantibayotiki ndi masiku 5.

Kuchiza sikuyenera kupitilira masiku opitilira 14 osanenapo za matenda. Ngati ndi kotheka, ndikotheka kuchitapo kanthu mankhwala oyambira (makolo oyamba a amoxicillin + clavulanic acid, otsatiridwa ndi makonzedwe apakamwa).

Akuluakulu ndi ana osaposa zaka 12 okhala ndi kulemera kwa thupi ≥ 40 kg Mankhwala ndi 500 mg / 125 mg katatu / tsiku.

Mlingo wapamwamba wa tsiku lililonse sayenera kupitirira 2400 mg / 600 mg patsiku.

Ana a zaka 1 mpaka zaka 12 ndi thupi lolemera 10 mpaka 40 kg Mlingo wa mankhwalawa umakhazikitsidwa payekhapayekha potengera matenda komanso kuopsa kwa matendawa.

Mlingo wovomerezeka tsiku lililonse umachokera pa 20 mg / 5 mg / kg patsiku mpaka 60 mg / 15 mg / kg patsiku ndipo umagawidwa pawiri.

Zotsatira zamankhwala pazogwiritsira ntchito amoxicillin / clavulanic acid pazowerengeka 4: 1 pa Mlingo> 40 mg / 10 mg / kg patsiku la ana osakwana zaka ziwiri. Mlingo wapamwamba wa tsiku lililonse wa ana ndi 60 mg / 15 mg / kg patsiku.

Mlingo wochepa wa mankhwalawa amalimbikitsidwa pochizira matenda amkhungu komanso minyewa yofewa. Palibe zambiri zachipatala zomwe zingapangitse kuti mankhwalawa agwiritsidwe ntchito mopitilira 40 mg / 10 mg / kg / tsiku mu 3-mgawo wogawika (4: 1) mwa ana osakwana zaka ziwiri.

Njira yolondola ya odwala omwe ali ndi ana yaperekedwa patebulo pansipa:

Flemoklav Solutab ® - malangizo a mapiritsi 500 mg

Mankhwalawa ndi mankhwala osakanikirana omwe amachokera ku gulu la zoletsa zoteteza penicillin.

Chofunikira chachikulu pa ntchito ndi amoxicillin + clavulanic acid.

- yodziwika ndi bactericidal zotsatira zolimbana ndi tizilombo tating'onoting'ono tambiri:

Gram-positive ndi gram-hasi aerobes Enterococcus faecalis, Gardnerella vaginalis, Streptococcus pyogene, Nocardia asteroids, Staphylococcus saprophyticus ndi aureus, Listeria monocytogene, Helicobacter pylori, Haemophilus fuluwenza, ndi paraleibiza.
Anaerobes Peptostreptococcus micros ndi magnus, Eikenella corrodens, mitundu ina ya fusobacteria, clostridia ndi peptococci.
Atypical causative wothandizila wa leptospirosis ndi syphilis.

Potaziyamu clavulanate (kapena clavulanic acid) mu kapangidwe kamankhwala amachulukitsa kuwonekera kwa zochita za antimicrobial za antibayotiki ndi kukhazikika kwake chifukwa cha kuletsa kwa beta-lactamases opangidwa ndi mabakiteriya. Kupanga kwa bactericidal kanthu ndikoyambitsidwa kwa chinthu chogwira ntchito mu khungu ndikutchingira biosynthesis ya peptidoglycan. Izi ndizofunikira pakumanga khoma la maselo, motero kusowa kwake kumayambitsa kufa kwa ma microorganism.

Kupanga kwamankhwala

Gawo lalikulu la mankhwalawa ndi amoxicillin, yomwe imapangidwa ndi clavulanic acid.

Inapangidwa mu 1972, amoxicillin adawonetsa kukana kwambiri kwa asidi ndi ntchito ya bactericidal kuposa ampicillin, koma adawonongedwa ndi beta-lactamases. Imalowetsedwa ndi thupi pafupifupi kwathunthu (ndi 94%), imagawidwa mwachangu, yopukutidwa makamaka ndi impso.

Kuwonongeka kwa mabakiteriya ndi beta-lactamases kuthetsedwa ndi kuwonjezeredwa kwa clavulanic acid, choletsa champhamvu cha ma enzymes owononga. Chifukwa cha mphete yowonjezereka ya beta-lactam, mankhwalawa apeza kukana kwambiri komanso mawonekedwe owonjezera a antimicrobial. The bioavailability wa potaziyamu clavulanate pafupifupi 60%, monga ndi gawo lalikulu, sizimatengera kupezeka kwa chakudya m'mimba.

Kutulutsa Fomu

Mankhwalawa amapangidwa mwa mawonekedwe a piritsi ndi kampani yopanga mankhwala Astellas ® kuchokera ku Netherlands. Mapiritsiwo ndi oyera (nthawi zina amakhala ndi zodera zofiirira) za utoto, zokulirapo, wopanda malo, wopanda zoopsa. Amasungunuka m'madzi, ndiye kuti, amwazikana, amalembedwa mbali imodzi. Manambala akuwonetsa zosankha, momwe mankhwalawa ali ndi anayi:

"421" - mapiritsi ali ndi 125 mg a amoxicillin ndi 31.25 mg wa clavulanic acid,
"422" - 250 ndi 62,5 zogwira ntchito, motsatana,
"424" - 500 ndi 125 milligram,
"425" - 875 ndi 125 (njirayi imatchulidwanso Flemoklav Solutab ® 1000 - poyerekeza kuchuluka kwa zosakanizira zazikulu).

Zojambulazo Flemoklav ® 875 mg + 125 mg kuchokera ku Astellas ®

Othandizira kupanga othandizira ndi microcrystalline cellulose, crospovidone, magnesium stearate, saccharin, vanillin ndi kununkhira kwa apricot. Mapiritsiwo ali ndi matuza a zojambulazo za zidutswa 5, zomwe zili phukusi ndi 20 tabu. Kusiyana ndi njira yodziwika ndi nambala ya "425" - pabokosi lamakatoni pamakhala matuza awiri, mapiritsi 7 aliwonse.

Zizindikiro za Flemoclav ®

Flemoklav Solutab ® wa mankhwalawa, malinga ndi malangizo, ayenera kugwiritsidwa ntchito ngati pakukula kwa matenda otsatirawa:

kutupa kwa mucous paranasal sinuses (sinusitis) - sinusitis, kutsogolo sinusitis, sphenoiditis, etc.
otitis media,
tonsillitis (tonsillitis) ndi pharyngitis,
bronchitis
chibayo chopezeka pagulu,
matenda a genitourinary (kuphatikizapo gynecological) - cystitis, pyelonephritis ndi ena,
zotupa zapakhungu za pakhungu, minofu ndi mafupa (osteomyelitis, nyamakazi yotsuka mafupa),
machira, phlegmon,
peritonitis
zovuta za septic.

Flemoklav Solutab ® yokhala ndi mkaka ndi pakati

Popereka mankhwala kwa amayi apakati mothandizidwa ndi mankhwalawa, palibe teratogenic zotsatira zomwe zapezeka, ngakhale kuti amoxicillin ndi potaziyamu clavulanate amalowa bwino kudzera chotchinga cha hematoplacental. Zinthu zomwe zimagwira mwachangu sizikhudza mwana wosabadwayo;

Kusamala kwakukulu mukamagwiritsa ntchito kuyenera kuwonedwa mu trimester yoyamba (panthawiyi, kuthekera kwa chithandizo ndi zoopsa zomwe zingachitike ziyenera kuyesedwa ndi dokotala). Ndikofunikira kugwiritsa ntchito mankhwalawa mosamalitsa malinga ndi malingaliro a katswiri kapena katswiri wina.

Ndikothekanso kutumiza Flemoklav Solutab ® ya HS: ziwalo zonsezo zimalowa mkaka wa m'mawere m'miyeso yayikulu, koma sizimavulaza mwana. M'maphunziro azachipatala, panalibe zoyipa za mankhwala opatsirana pa microflora ndi mkhalidwe wamba wa makanda.Komabe, ngati hypersensitivity yapezeka mwatsopano komanso m'mimba, mucosal candidiasis kapena matupi awo amachitika, kuyamwitsa kuyenera kuyimitsidwa nthawi yayitali ya mankhwalawa. Pankhaniyi, ndikofunikira kufotokoza mkaka kuti mkaka wa m'mawere usathe.

Flemoklav Solutab ®: ndandanda ya Mlingo ndi Mlingo

Mapiritsi amatha kumwedwa m'njira ziwiri: poyambira kusungunulira kapu ya madzi oyera kapena kungomeza ndi kumwa. Izi zikuyenera kuchitika musanadye, popeza mitundu ya zipatso imatha kutulutsa msana. Kupezeka kwa chakudya m'mimba m'mimba sikumakhudza mayamwidwe ndi bioavailability wa clavulanic acid ndi amoxicillin.

Mlingo wothandizira komanso nthawi yoyenera yovomerezeka imatsimikiziridwa ndi dokotala wodziwa nokha (mankhwala omwe amadzichiritsa okha ndi osavomerezeka) malinga ndi kuopsa kwa maphunziridwe ake komanso momwe matendawo aliri.

Kuwerengera Mlingo kumachitika pa amoxicillin.

Nthawi zambiri, mankhwala amaikidwa motere:

Odwala akulu ndi ana opitirira zaka khumi ndi ziwiri amalimbikitsidwa kuti atenge 500 mg maola 8 aliwonse (kutanthauza katatu patsiku), kapena ma milligram 875 a chinthu chogwiritsidwa ntchito ndi maola 12. Ngati mukudwala matenda obwereza komanso makamaka osakhazikika, muyezo wa tsiku ndi tsiku uwonjezeke. Perekani 875-1000 mg wa amoxicillin katatu patsiku.
Kwa ana ochepera zaka khumi ndi ziwiri, Flemoklav Solutab ® 125 mg ndi mankhwala, ndiye kuti. Mapiritsi okhala ndi maantibayotiki okhala ndi 250 ndi 500 mg amagwiritsidwanso ntchito ngati matendawa ali oopsa. Kuyambira kuyambira wazaka ziwiri, mlingo wa tsiku ndi tsiku uyenera kuwerengedwa malinga ndi kulemera kwa thupi - 20-30 mg pa kilogalamu ya kulemera. Pafupipafupi, izi ndi 125 mg katatu patsiku kwa mwana kuyambira zaka 2 mpaka 7 ndi milligram 250 molingana ndi chiwembu chomwechi kwa ana azaka 7 mpaka 12.
Mapiritsi okhala ndi 875 mg yogwira ntchito samayikidwa kwa anthu omwe ali ndi vuto la impso komanso osasinthika a glomerular osakwana 30 ml pa mphindi. Pankhaniyi, mlingo nthawi zambiri umatheka.

Kusamala kugwiritsa ntchito mosamala kumafuna chithandizo cha odwala omwe ali ndi vuto lalikulu la chiwindi. Kuyang'anira wodwala nthawi zonse ndikuwongolera kwake ndikuyenera kuvomerezedwa.

Kutalika kwa mankhwala opha maantibayotiki nthawi zina sayenera kupitirira masabata awiri.

Kuchulukitsa Mlingo wolimbikitsidwa kumakhala ndi vuto la dyspeptic. Wodwalayo amakhala ndi mseru, kusanza, kutsegula m'mimba. Zotsirizazi zimatha kuchitika kwambiri ndipo zimayambitsa kusowa kwamadzi. Mankhwala osokoneza bongo amathandizidwa mosiyanasiyana ndi ntchito ya enterosorbent (yodziyambitsa kaboni) ndikubwezeretsa mulingo wa electrolyte wamadzi. Chizindikiro chotsutsa chikachitika, Diazepam ® imayikidwa, ndipo kulephera kwa impso kumafunika hemodialysis.

Flemoklav Solutab ®: bongo ndi zotsatira zoyipa

Amoxicillin osakanikirana ndi potaziyamu clavulanate samasokoneza thupi la wodwalayo, chifukwa ma penicillin maantibayotiki nthawi zambiri amakhala ndi poizoni. Komabe, pa mayesero azachipatala ndi maphunziro owerengera otsatsa, zotsatirazi poyankha mankhwalawo kuchokera ku ziwalo zamkati ndi machitidwe zidazindikirika:

Tizilombo ta m'mimba ndi chiwindi. Ululu wa epigastric, vuto la chopondapo (m'mimba), kusanza, ndi mseru ndizosowa. Ngakhale kawirikawiri, kukanika kwa chiwindi mu mawonekedwe a jaundice kunadziwika, komanso kukula kwa pseudomembranous colitis padera. Monga lamulo, mavuto a chimbudzi samachitika ngati mumwa mankhwalawa monga momwe analangizira - musanadye.
Chitetezo cha mthupi. Pafupipafupi (pazochitika zochepa pa chikwi) zimatha kusokoneza monga exanthema ndi urticaria zimachitika. Vuto lakhansa komanso multiform erythema, vasculitis, angioedema, ndi exfoliative dermatitis ndizochulukirapo.
Ziwalo zoberekera. Mwina chitukuko cha interstitial nephritis.

Zotsatira zina zoyipa zimaphatikizira ndi candidiasis yokhala ndi mankhwala opha maantibayotiki, omwe amakwiya chifukwa cha kutseguka kwa microflora ya pathogenic ya mucous nembanemba. Palinso kuthekera kwa kudalirika kopitilira muyeso komanso mantha anaphylactic.

Mndandanda wa zoyipa zomwe zimachitika mthupi zimadziwika ndi mankhwala Mlingo wa 125 mpaka 500 mg. Mlingo wowonjezereka (mapiritsi olembedwa "425") amatha kuyambitsa mavuto ena osowa: kusinthika kwa hematopoiesis (hemolytic anemia), chifuwa, kupweteka mutu, kukokana, kuchuluka kwa nkhawa, kusowa tulo, kuchuluka kwa mphamvu ya chiwindi.

Flemoklav ndi Amoksiklav ®: pali kusiyana kotani?

Mankhwala Amoxiclav ®, opangidwa ndi kampani ya mankhwala Lek (Slovenia), nawonso ali m'gulu la penicillin otetezedwa ndi zoletsa.

Chofunikira chachikulu ndi mankhwala amooticillin omwe amapanga mphamvu ngati hydrosrate, yoteteza khungu la clavulanic acid. Ndiko kuti, mankhwalawa ndi analogue yathunthu ya Flemoklav ® ndipo amagulitsidwa m'makementi a pharmacy pamitengo yovomerezeka.

Kusiyana pakati pa ma antibacterial othandizira awa ali mumitundu yosiyanasiyana ya mtundu wa Chisiloveniya ndi zina mwazomwe zimapangidwira. Amoxiclav ® imapangidwa zonse ngati mapiritsi omwazika komanso ochiritsira, komanso mu mawonekedwe a ufa wophatikizira ndi njira yothandizira yogwiritsa ntchito.

Mapiritsi okhala ndi mafilimu amakhala ndi mitundu yosiyanasiyana ya maantibayotiki (kuyambira 250 mpaka 875 mg), komabe, kuchuluka kwa potaziyamu clavulanate nthawi zonse kumakhala chimodzimodzi - 125 milligrams. Mitundu yosiyanasiyana ya Amoxiclav-Quicktab ® imadziwika ndi zomwezi. Ufa umakhala ndi zosakaniza zofananira zosiyanasiyana.

Mitundu yambiri ya Mlingo imakulitsa kukula kwa antiotic. Matenda am'mimba, chancre ndi gonorrhea amawonjezedwa pamndandanda wazowonetsa. Kuphatikiza apo, yankho la mankhwalawa limagwiritsidwa ntchito ngati prophylactic pakuchita maopaleshoni. Komanso, zoletsa zaka zimachotsedwa: kholo, mankhwalawa amatha kukhazikitsidwa kuyambira masiku oyamba a moyo wa mwana, ndipo mwa mawonekedwe a kuyimitsidwa - kuyambira miyezi iwiri.

Ndemanga ya Flemoklav Solutab ®

Madokotala osiyanasiyana apadera adziwa kuyamikiridwa kwa mankhwalawo ndipo nthawi zambiri amalimbikitsa kuti athandizire odwala ndi ana. Mu ana a matenda a kupuma, ma atitis media ndi sinusitis, mankhwalawa amatenga imodzi mwazomwe akutsogolera pamndandanda wa mankhwala. Kuchita kwake kwapamwamba kumadziwika pamodzi ndi ma contraindication ochepa komanso zoyipa.

Ndemanga za odwala zilinso zabwino. Anthu ambiri omwe amagwiritsa ntchito mankhwalawa amati kusinthaku kwathanzi komanso kutha kwa zizindikiro za matendawa, kuchiritsa kwamatenda amtundu komanso matenda opatsirana osalephera (ndizodziwika bwino kuti kubereka si kuphwanya). Ngakhale zili choncho, wina amathanso kupeza nkhani zabodza zokhudza Flemoklava ®. Monga lamulo, mwa iwo odwala amadandaula za zotsatira za mankhwalawa (thrush, nseru, kupweteka m'mimba, kutsegula m'mimba, ndi zina zambiri).

Komabe, kusanthula kwa chidziwitso ichi kumatipatsa mwayi woweruza kuti milandu yonse yomwe ikufotokozedwayi imachepetsedwa ndikugonjera panthawi ya mankhwala othandizira. Komabe, vuto lalikulu ndi nseru ndi kupweteka kwa epigastric, komwe kumachitika chifukwa chosagwiritsidwa ntchito molakwika (i., Pamimba yopanda kanthu). Palinso kusakhutira kwapang'onopang'ono ndi kukoma kwa mapiritsi (sikuti aliyense amakonda fungo), zomwe sizimalola ena kuti awasungunule.

Ndemanga za Flemoklava Solutab 500

Tamara, wazaka 30, Krasnodar.

Banja lonse limagwiritsa ntchito Flemoklav ndi angina, sinusitis kapena otitis media. Zimathandiza mwachangu mokwanira, sizifunikira kutsatira malamulo apadera, sipanakhalepo zoyipa zilizonse.

Alena, wazaka 42, Samara.

Chimodzi mwazida zabwino kwambiri pamtengo wotsika mtengo. Amathandizira msanga, amathandizanso kutentha, kutupa, kukonza bwino zinthu kuchokera muyezo woyamba. Ndikupangira izi kwa aliyense.

Irina, wazaka 21, Omsk.

Amayi amadwala matendawa komanso pharyngitis. Nthawi zonse nthawi yowonjezera imagwiritsa ntchito Amoxiclav kapena Flemoklav. Chida chabwino kwambiri chomwe chimachotsa bwino zomwe zimayambitsa matendawa komanso zomwe zimayambitsa matendawa.

Mankhwala

Amoxicillin ndi anti-spectrum yoteteza antijeni wina wama semisynthetiki, akuwonetsa zochita motsutsana ndi michere yambiri yama gramu-gram komanso gram. Komabe, thunthu limatha kuwonongeka motsogozedwa ndi beta-lactamases, chifukwa chake, tizilombo tating'onoting'ono tomwe timapanga enzyme imeneyi timagwirizana ndi amoxicillin. Clavulanic acid ndi beta-lactamase inhibitor ndipo imafanana ndi ma penicillin, omwe amachititsa kuthekera kosakhazikika kwamtundu wa beta-lactamase omwe amapezeka mu tizilombo tating'onoting'ono ta cephalosporins ndi penicillin.

Clavulanic acid imawonetsa mphamvu yokwanira yolimbana ndi plasmid beta-lactamases, yomwe imakonda kupangitsa mabakiteriya kukana, komabe, kugwira kwake ntchito motsutsana ndi chromosomal beta-lactamase a mtundu 1, omwe palibe zoletsa za clavulanic acid, ndizochepa. Kuphatikiza kwa amoxicillin ndi clavulanic acid kumateteza ku chiwonongeko ndi ma enzymes a beta-lactamase, omwe amathandizira kukulitsa mawonekedwe a antibacterial a amoxicillin.

Mu vitro, ma tizilombo totsatirawa timakonda kwambiri mankhwala:

gram-negative anaerobes: Prevotella spp., Bacteroides fragilis, Bacteroides spp., Porphyromonas spp., Fusobacterium spp., Fusobacterium nucleatum, Capnocytophaga spp., Eikenella corrodens,
grid-ana anaerobes: Peptostreptococcus spp., Peptostreptococcus micros, Peptostreptococcus magnus, Peptococcus niger, Clostridium spp.,
gram-negative aerobes: Vibrio cholerae, Bordetella pertussis, Pasteurella multocida, Haemophilus influenzae, Neisseria gonorrhoeae, Moraxella catarrhalis, Helicobacter pylori,
gram-positive aerobes: coagulase-negative staphylococci (kuwonetsa kukhudzika kwa methicillin), Staphylococcus saprophyticus ndi Staphylococcus aureus (tizilombo ta chidwi cha methicillin), Bacillus anthracis, Streptococcus spp. (beta hemolytic streptococci), Streptococcus agalactiae, Streptococcus pyogenes, Enterococcus faecalis, Listeria monocytogene,
osiyana: Treponema pallidum, Leptospira icterohaemorrhagiae, Borrelia burgdorferi.

Ma tizilombo totsatirawa amakhulupirira kuti ali ndi mphamvu zotsutsana ndi Flemoklav Solutab:

gram-aerobes gram: streptococci of the Viridans group, Streptococcus pneumoniae, Enterococcus faecium, Corynebacterium spp.,
gram-negative aerobes: Shigella spp., Escherichia coli, Salmonella spp., Proteus spp., Proteus vulgaris, Proteus mirabilis, Klebsiella spp., Klebsiella pneumoniae, Klebsiella oxytoca.

Zamoyo zotsatirazi zikuwonetsa kukana kwachilengedwe pakuphatikizidwa kwa amoxicillin ndi clavulanic acid:

gram-negative aerobes: Yersinia enterocolitica, Acinetobacter spp., Stenotrophomonas maltophilia, Citrobacter freundii, Serratia spp., Enterobacter spp, Pseudomonas spp., Hafnia alvei, Providencia spp.
Ena: Mycoplasma spp., Chlamydia spp., Chlamydia psittaci, Chlamydia pneumoniae, Coxiella burnetii.

Malangizo ogwiritsira ntchito Flemoklava Solutab: njira ndi mlingo

Mapiritsi amatengedwa pakamwa musanadye, kumeza lonse ndikumwa 200 ml ya madzi kapena kusungunuka mu 100 ml ya madzi ndikusunthira bwino musanagwiritse ntchito.

Mlingo woyenera wa akulu ndi ana omwe ali ndi thupi lolemera kuposa 40 kg:

Flemoklav Solutab 875 mg + 125 mg: piritsi limodzi katatu patsiku (maola 12 aliwonse),
Flemoklav Solutab 500 mg + 125 mg: piritsi limodzi katatu patsiku (maola 8 aliwonse). Mankhwalawa aakulu, pafupipafupi, matenda oopsa, mankhwalawa atha kuchulukitsidwa kawiri.

Mlingo wa tsiku ndi tsiku wa ana osaposa zaka 12 ndi thupi lofika mpaka 40 makilogalamu nthawi zambiri amadziwonetsa pa 20-30 mg ya amoxicillin ndi 5-7,5 mg wa clavulanic acid pa 1 kg ya kulemera kwa mwana.

Mlingo woyenera wa ana:

Zaka 7 - 12 (25-37 makilogalamu): Flemoklav Solutab 250 mg + 62,5 mg - piritsi limodzi katatu patsiku,
Zaka 2 - 7 (13-25 makilogalamu): mankhwala a 125 mg + 31.25 mg - piritsi limodzi katatu patsiku,
Miyezi itatu - zaka ziwiri (5-12 makilogalamu): mapiritsi a 125 mg + 31.25 mg - imodzi iliyonse. 2 pa tsiku.

Ndi chiwonetsero chazachipatala chachikulu, mankhwalawa a ana amatha kuchulukitsidwa, pokhapokha ngati mlingo wa tsiku ndi tsiku usapitirire 60 mg ya amoxicillin ndi 15 mg ya clavulanic acid pa 1 kg ya thupi.

Kutalika kwa chithandizo sikupitilira masiku 14. Ngati mukufuna kugwiritsa ntchito mankhwalawa kwa nthawi yayitali muyenera kuonana ndi dokotala.

Amoxicillin dosing regimen ya odwala omwe amalephera kuwonongeka a impso amasinthidwa ndi GFR:

10-30 ml / mphindi: achikulire - 500 mg 2 kawiri pa tsiku, ana - 15 mg pa 1 kg 2 pa tsiku,
osakwana 10 ml / mphindi: achikulire - 500 mg patsiku, ana - pa mlingo wa 15 mg pa 1 kg patsiku.

Odwala a Hemodialysis akulangizidwa kuti atenge Flemoklav Solutab mu kumwa: akulu - 500 mg patsiku ndi 500 mg nthawi yochepa ndi kuyimba, ana - 15 mg pa 1 kg ya kulemera kwa tsiku ndi 15 mg pa 1 kg ya kulemera panthawi ndi pambuyo pa dialysis.

Zotsatira zoyipa

Kuchokera mmimba dongosolo: Nthawi zambiri - nseru, kusanza, kupweteka kwam'mimba, kuphwanya, kutsegula m'mimba, matenda am'mimba, kawirikawiri - hemorrhagic colitis, matumbo a m'mimba, discoloration ya kumtunda kwa dzino enamel,
thupi lawo siligwirizana: Nthawi zambiri - kuyabwa khungu, zotupa, ngati supanthema pambuyo masiku 5-11, urticaria, kawirikawiri mankhwala kutentha, exfoliative kapena oxous dermatitis (Stevens-Johnson syndrome, erythema multiforme, poyizoni epermermal necrolysis), erosis, anaphylactic mantha, laryngeal edema, Quincke edema, hemolytic anemia, seramu matenda, interstitial nephritis, Matupi vasculitis,
Kuchokera ku hemopoietic dongosolo: kawirikawiri - hemolytic anemia, thrombocytosis, kawirikawiri - kuchepa kwa magazi, leukopenia, thrombocytopenia, granulocytopenia, pancytopenia (zimachitika ndikusintha),
Kuchokera pakupangika kachulukidwe: kawirikawiri - kuwonjezeka kwa nthawi yamagazi ndi nthawi ya prothrombin (zochita zimasintha),
Kuchokera pamtima dongosolo: kawirikawiri - vasculitis,
kuchokera kwamanjenje: kawirikawiri - kupweteka mutu, chizungulire, kupweteka, kawirikawiri - kusowa tulo, kukhudzika, nkhawa, kuda nkhawa, kuchita zinthu mwamtopola, chikumbumtima chovulala,
mbali ya chiwindi: Nthawi zambiri - kuwonjezeka pang'ono kwa ntchito ya michere ya chiwindi, kawirikawiri - cholestatic jaundice, hepatitis (chiwopsezo chikuwonjezeka ndi kutalika kwa mankhwalawa kwa masiku opitilira 14, zovuta zimasinthidwa, koma nthawi zina zimatha kukhala zovuta, komanso mwa odwala omwe ali ndi zovuta zambiri). kwambiri concomitant pathologies kapena mankhwalawa akaphatikizidwa ndi mankhwala omwe angakhale ndi hepatotoxic, imfa ndiyotheka),
Kuchokera kwamtundu wa genitourinary system: pafupipafupi - kuwotcha ndi kumaliseche, kuyabwa, kawirikawiri - nephritis
ena: pafupipafupi - motsutsana ndi maziko ogwiritsidwa ntchito kwa nthawi yayitali kapena maphunziro obwereza, kungayambitse matenda a fungal kapena bakiteriya.

Malangizo apadera

Pali chiopsezo chotenga kukana kwamtanda ndikuwonjezera chidwi mukamagwiritsa ntchito Flemoklav Solutab ndi mankhwala ena a penicillin kapena cephalosporin.

Ndi chitukuko cha anaphylactic reaction, makonzedwe a mapiritsi ayenera kuthetsedwa mwachangu ndi kupeza chithandizo chamankhwala choyenera. Wodwala angafunike kuyambitsidwa kwa adrenaline (epinephrine), glucocorticosteroids (GCS), kubwezeretsa mwachangu ntchito yopuma.

Kuchepetsa kukula kwa zoyipa m'mimba, Flemoklav Solutab tikulimbikitsidwa kuti adyedwe musanadye.

Maonekedwe a urticaria m'masiku oyambirira a mankhwalawa kwambiri mwina angawonetse mavuto omwe amabwera chifukwa cha mankhwalawa, motero, kuchotsedwa kwake kumafunika.

Sipangakhale chofunikira kupatsa Flemoklav Solutab panthawi yovutitsa kwambiri m'mimba limodzi ndi kusanza komanso / kapena m'mimba, popeza kuyamwa kwa mankhwalawa kumatupa.

Ndi kukula kwa mphamvu, ndikofunikira kubwereza moyenera mankhwala othandizira kapena kusiya mankhwala.

Pankhani ya kukalamba kwa hemorrhagic colitis kapena pseudomembranous colitis, chizindikiro chomwe chingakhale mawonekedwe a kupitilira kwam'mimba kwambiri m'mimba, tikulimbikitsidwa kuti Flemoklav Solutab aletsedwe ndipo wodwala amayenera kupatsidwa chithandizo choyenera chothandizira. Muzichitika izi, othandizira ofooketsa matumbo a matumbo sangathe kugwiritsidwa ntchito.

Odwala omwe ali ndi vuto la chiwindi amayenera kuperekedwa pafupipafupi. Popanda kuwunika momwe chiwindi chikugwirira ntchito, mapiritsi sayenera kumwa kwa masiku opitilira 14.

Zizindikiro za vuto la chiwindi chogwira ntchito zimatha kuchitika pakumwa komanso pambuyo poti mwasiya mankhwala, nthawi yomweyo kapena patatha milungu ingapo. Nthawi zambiri amapezeka mwa odwala azaka zopitilira 60 ndi amuna, osadziwika kwambiri mwa ana.

Ndikofunikira kuyang'anira ma coagulation am'magazi mwa odwala omwe amalandila chithandizo cha anticoagulant, popeza momwe Flemoklav Solutab amatha kuwonjezera nthawi ya prothrombin.

Chifukwa cha kuchuluka kwa amoxicillin mu mkodzo ndi kuchuluka kwake pamakoma a catheter kwamkodzo, odwala amafunika kusintha kawirikawiri catheters awo. Kugwiritsa ntchito njira kukakamiza diuresis imathandizira kutuluka kwa amoxicillin ndipo idzachepetsa ndende yake mu plasma.

Panthawi yamankhwala, kugwiritsa ntchito njira zopanda enzymatic pakupanga shuga mu mkodzo komanso kuyeserera kwa urobilinogen kungapereke zotsatira zabodza.

Tiyenera kukumbukira kuti potaziyamu wambiri wopezeka piritsi limodzi la 875 mg / 125 mg ndi 25 mg.

Panthawi yamankhwala, kuwunika bwino ntchito ya chiwindi, impso, ndi ziwalo za hematopoietic kumafunika.

Ukakomoka kumachitika wodwala, Flemoklav Solutab amachotsedwa.

Kukopa pa kuthekera koyendetsa magalimoto ndi njira zowerengeka

Kafukufuku wazokhudza mphamvu ya mankhwalawa pa kuyendetsa magalimoto ndi kugwira ntchito zovuta sanachitidwe. Popeza kugwiritsa ntchito Flemoklav Solutab kumatha kuyambitsa mavuto (mwachitsanzo, chizungulire, kukhumudwa, matupi awo), odwala ayenera kudziwa za kusamala poyendetsa kapena kugwira ntchito yomwe imafuna kuti anthu azikhala ndi chidwi.

Kuyanjana kwa mankhwala

Akaphatikizidwa mu vitro ndi othandizira ena a bacteriostatic (kuphatikizapo sulfonamides, chloramphenicol), kukhudzana ndi mankhwala kunadziwika.

Sayenera kuphatikizidwa ndi disulfiram.

Pogwiritsa ntchito munthawi yomweyo Flemoklav Solyutaba:

phenenecid, oxyphenbutazone, phenylbutazone, acetylsalicylic acid, sulfinpyrazone, indomethacin - amachedwetsa kuphipha kwa impso ndi amoxillin ndikuwonjezera kuchuluka kwa nthawi yayitali ndikutsalira kwa amoxicillin mu bile ndi plasma ya magazi (izi sizimakhudzana ndi excretion ya clavulanic acid)
Maantacid, zotupa, glucosamine, aminoglycosides - amachepetsa ndikuchepetsa kuyamwa kwa amoxicillin,
ascorbic acid - imayambitsa kuwonjezeka kwa mayamwidwe a amoxicillin,
allopurinol - chiopsezo chotenga chotupa pakhungu chikuchulukitsidwa,
sulfasalazine - ingachepetse mawonekedwe ake a seramu,
methotrexate - imachepetsa kukhudzika kwa impso, imawonjezera chiopsezo chakuwonjezera kwake poizoni.
digoxin - imakulitsa mayamwidwe,
anticoagulants - angawonjezere ngozi yotulutsa magazi,
njira zakulera za pakamwa za mahomoni - zimatha kuchepa mphamvu.

Zofanizira za Flemoklav Solutab ndi: Trifamox IBL, Amoxiclav 2X, Rekut, Augmentin, Augmentin SR, Panclave, Bactoclav, Medoclav, Klavam, Arlet, Ekoklav, Sultasin, Oxamp, Oxamp-Sodium, Amoxil K 625, Ampisid.

Mtengo wa Flemoklav Solyutab m'masitolo ogulitsa mankhwala

Mitengo yoyandikira ya Flemoklav Solyutab m'masitolo azachipatala kutengera mtundu wake:

Flemoklav Solutab 125 mg + 31.25 mg (20 ma PC mu phukusi) - 304-325 ma ruble,
Flemoklav Solutab 250 mg + 62.5 mg (20 zidutswa zikuphatikizidwa) - 426‒437 rubles,
Flemoklav Solutab 500 mg + 125 mg (20 zidutswa zikuphatikizidwa) - 398‒456 rubles,
Flemoklav Solutab 875 mg + 125 mg (zidutswa 14 zimaphatikizidwa ndi phukusi) - 430‒493 rubles.

Malangizo a Flemoklav Solutab

Malangizo ogwiritsira ntchito Flemoklav Solutab amalimbikitsa kuti akuluakulu, ana osaposa zaka 12 ndi ana osaposa zaka khumi ndi ziwiri okhala ndi kulemera kwama kilogalamu oposa 40 amatenga maantibayotiki pa mlingo wa 875 + 125 mg (kuchuluka kwathunthu kwa zosafunikira - 1000 mg) kawiri pa tsiku (kwa matenda aakulu, oopsa, kubwereza matenda opatsirana kawiri).

Ana osaposa zaka 12 ndi osaposa 40 kilogalamu amawagwiritsa ntchito mankhwalawa muyezo wofooka (Flemoclav 250 mg + 62,5 mg ndi Flemoclav 500 mg + 125 mg).

Flemoklav Solyutab 500mg + 125mg katatu patsiku amalimbikitsidwa kwa akuluakulu ndi ana olemera 40 kg kapena kupitilira.

Mlingo wa tsiku ndi tsiku wa ana osakwana zaka 12 ndi masekeli mpaka 40 ndi 5 mg clavulanic acid ndi 25 mg amoxicillin pa kilogalamu ya kulemera.

Mu matenda opatsirana opatsirana komanso otupa, Mlingo uwu ukhoza kuchulukitsidwa, koma ndizoletsedwa kupitirira mlingo wa 60 mg amoxicillin ndi 15 mg clavulanic acid pa kilogalamu ya kulemera kwa thupi patsiku.

Kutalika kwa mankhwala ndi mankhwala sayenera kupitilira milungu iwiri.

Odwala ndi concomitantkulephera kwa aimpso Flemoklav Solutab 875 mg / 125 mg ungagwiritsidwe ntchito ngati kuchuluka kwa mafupa a impso ndi oposa 30 ml pa mphindi.

Kuchepetsa chiwopsezo cha mavuto obwera chifukwa chogaya chakudya, mankhwalawa amalimbikitsidwa kuti atenge mankhwala musanadye. Piritsi liyenera kumezedwa lonse, kutsukidwa ndi madzi, kapena kusungunuka mu 50 ml ya madzi, kukonzedwa kwathunthu musanagwiritse ntchito.

Kodi pali kusiyana kotani pakati pa Flemoxin Solutab ndi Flemoklav Solutab?

Nthawi zambiri, odwala amafunsidwa mafunso - kusiyana kwake ndi chiyani Flemoxin kuchokera kwa Flemoklav? Kuti mumvetsetse kusiyana kwake ndikosavuta: Flemoklav, mosiyana ndi Flemoxin, ali ndi clavulonic acid, amene amaletsa kuwonongedwa kwa mamolekyulu atizilombo toyambitsa matenda, omwe amakhudza bwino zambiri zomwe zikusonyeza mphamvu ya mankhwalawa.

Flemoklav Solutab wa ana

Gawo "Malangizo a Flemoklav Solutab"Zikuwonetseratu momwe mungamwere mankhwalawa kwa ana. Mlingo woyenera tsiku lililonse wa ana sayenera kupitirira 15 mg clavulanic acid ndi 60 mg amoxicillinndi kilogalamu ya kulemera.

Mauthenga okhudzana ndi zovuta zomwe zimachitika nthawi zambiri sizachilendo kuwunika ana. Mtengo wa Mlingo wocheperako wa mankhwalawa umafananizidwa bwino ndi mtengo wa Flemoklav Solutab pa mlingo wa 875/125 mg.

Pa mimba ndi mkaka wa m`mawere

Adanenanso zakupweteka kwa mwana wosabadwa kapena wakhanda amoxicillin ndi clavulanic acid osalembedwa.

Kugwiritsa ntchito pakatha milungu 13 ya mimba ndikotheka pokhapokha malinga ndi madokotala. M'milingo yoyambirira 12 ya mimba, mankhwalawa amadziwikiridwa mu mlingo wa 875/125 mg.

Zinthu zogwira zimalowa placenta ndi kudutsa mkaka wa m'mawere. Izi sizikuletsa kugwiritsa ntchito mankhwalawa panthawi yoyamwa, koma iyenera kugwiritsidwa ntchito mosamala.