Vitaxone - mankhwala ochepetsa mavitamini othandizira kupweteka
Vitaxone ndi mankhwala a neurotropic Mavitamini Bzomwe zimakhala ndi phindu pa kusokonekera ndi / kapena yotupa nyengo zopweteka musculoskeletal ndi wamanjenje kachitidwe. Gulu la mankhwalawa limawonetsedwa kuti lipewe zoperewera.
Mlingo wambiri umakhala bwino magazikuwonetsera analgesic kwenikweni, kumathandizira kusintha kwa njira hematopoiesis ndi zochitika dongosolo lamanjenje.
Chimodzi mwazomwe zimagwira vitamini b1 phosphorylating mu thupi amapanga biologicia zinthu: thiamine triphosphate (TTR) ndi thiamine diphosphate (cocarboxylase) Zingatheke bwanji coenzyme, cocarboxylase amatenga nawo mbali kagayidwe kachakudya njira ulusi wamitsempha ndi njira chakudya kagayidwe kachakudyamosiyanasiyana amakhudza mayendedwe misempha.
Ndi kuperewera Vitamini B1kukopa kwa metabolites mu minofu kumachitika, choyambirira pyruvic ndi lactic acid, zomwe zimatha kudzetsa mavuto osiyanasiyana komanso mawonekedwe amomwe magwiridwe antchito amanjenje.
Fosphorylated mawonekedwe vitamini b6 (pyridoxal-5'-phosphate, PALP) ndi coenzyme magulu a ma enzymes omwe amagawidwa pofanana Amino acid kagayidwe (non-oxidative). Pogwiritsa ntchito decarboxylation, amatenga nawo mbali popanga ma amino olimbitsa thupi (histamine, adrenaline, serotonin, tyramine, dopamine etc.), kudzera transamination nawo catabolic ndi anabolic kagayidwe kachakudya njira (mwachitsanzo glutamate oxalacetate transaminase) ndi njira zingapo zobwereza komanso zomveka bwino ma amino acid.
Pyridoxine imakhudza magawo anayi osiyanasiyana a kutembenuka kwa metabolic tryptophanat hemoglobin kaphatikizidwe imagwira ntchito ngati chothandizira kupangira asidi α-amino-β-ketoadinin.
Vitamini B12chofunikira pakuchita cell kagayidweimakhudza hematopoietic ntchito (antianemic factor), akukhudzidwa ndi mapangidwe methionine, choline, ma nucleic acid, creatininechikuwonetsa ntchito ya analgesic.
Mukamamwa pakamwa, mothandizidwa ndi matumbo phosphatases, dephosphorylation benfotiamine limapezeka kwa mafuta osungunuka a S-benzoyl thiamine (SBT), yemwe ali ndi mphamvu zochulukirapo ndipo amakamizidwa popanda kutembenuka kwakukulu thiamine.
Zogulitsa pyridoxine, monga zotumphukira zake, zimachitika mwachangu kumtunda kwam'mimba pogwiritsa ntchito kulowetsedwa, ndikamasulidwa kwa maola 2-5. Pyridoxal ndi pyridoxal-5-phosphate mu plasma albin. Pyridoxal ndi mawonekedwe onyamula. Zolowera kudzera mu cell zimagwira ndi cell albin pyridoxal 5-phosphate ndi hydrolyzed mkati pyridoxal ndi thandizo zamchere phosphatase.
Benfotiaminosati thiamine, ziwonetsero za kudzikongoletsa sizachilendo. Pa nthawi yomwe mayamwidwe amadzimadzi amadzimadzi Vitamini B1 amakhalabe otsika kwambiri, bioavailability benfotiamine chikufanana pafupifupi 100%. Komanso benfotiamine amakhala nthawi yayitali mu minofu.
Ndi kuyambitsa kwa mankhwalawa, kugawa kwa makolo kumachitika thiamine mthupi. Pafupifupi 1 mg thiamine zotheka kagayidwe tsiku lililonse, ndi excretion wa metabolites kudzera impso. Njira ya dephosphorylation imawonedwa mu impso, ndi T1 / 2 pafupifupi mphindi 21. Chifukwa otsika mafuta solubility wa cumulation thiamine mu thupi samawonedwa.
Kusintha kwa jekeseni ndikuchotsa pyridoxine zimachitika molingana ndi chiwembu chofanana ndi chakumwa pakamwa.
Ndi kholo makonzedwe cyanocobalamin amapanga mapuloteni onyamula ma protein omwe amatengeka mwachangu m'mafupauvunieWatsopano ndi matupi ena. Vitamini B12 amalowa mu bile ndipo amatenga mbali m'matumbo-hepatic, komanso amalowa placenta.
Mapiritsi a Vitaxone
Zizindikiro mankhwala osiyanasiyana opweteka amanjenje:
- mowa ndi matenda ashuga polyneuropathy,
- zamitsempha matenda a systemic chikhalidwe, chifukwa kuchepa kwa mavitamini B1, B6.
Jakisoni wa Vitaxon
Pathological zikhalidwe za minyewa mbali zosiyanasiyana:
- neuralgia,
- tinea versicolor,
- myalgia,
- mowa ndi matenda ashugapolyneuropathy,
- radicular syndrome,
- neuritis,
- ziwalo,
- retrobulbar neuritis.
Makhalidwe
Kuphatikizika kwa mankhwalawa kumaphatikizapo mavitamini a B, omwe mu zovuta kuchipatala amathandizira kuthana ndi mavuto mu minofu ndi mafupa ochiritsa matenda amanjenje. Imayendetsa magazi ndi njira yopanga magazi. Chifukwa cha izi, kagayidwe ndi momwe machitidwe amanjenje amayambira.
Vitaxone imagwira ntchito munthawi ya rekodi chifukwa imayamwa mu mnofu woyamba mphindi 15 pambuyo pa mankhwala. Chodabwitsa cha mankhwalawa ndikuti zigawo zomwe zimagwira zimadziunjikira m'thupi ndikupatsa munthu kuchuluka kwa vitamini B, ngakhale atatha kulandira chithandizo.
"Vitaxone" imapangidwira chitetezo chamthupi. Kutsogolera maphunziro a matendawa, mankhwalawa amatchulidwa muyezo, womwe umakuthandizani kuti muchepetse ululu
Malinga ndi malangizo, mankhwala amakonzekera matenda amitsempha yamaukadaulo osiyanasiyana:
- matenda a mtima wamitsempha,
- kupweteka minofu yomwe imadziwika kuti imakhala yopepuka komanso yopsinjika,
- kuwonongeka kwamitsempha yamagetsi, yomwe imatha kukhazikitsidwa chifukwa cha uchidakwa kapena matenda ashuga,
- mpumulo wa radicular syndrome,
- kupuwala nkhope
- mankhwalawa retobulbar neuritis,
- tinea versicolor
- pa matenda a chapakati ndi zotumphukira mantha dongosolo poizoni ndi mtima,
- matenda amitsempha, akukhala motsutsana ndi maziko a kuchepa kwa mavitamini a gulu B.
Kuphatikizika ndi mawonekedwe a kumasulidwa kwa mankhwalawa
Mankhwala "Vitaxone", kwenikweni, mavitamini a gulu B. Mankhwalawa amapezeka mu mawonekedwe a mapiritsi ndi yankho la jakisoni. Mapiritsi okhala ndi mawonekedwe ndi zokutira. Zinthu zomwe zimagwira ntchito pamenepa ndi benfotiamine ndi pyridoxine hydrochloride. Piritsi limodzi lili ndi 100 mg ya zinthu izi.
Monga zida zothandizira, chimanga, cellcrystalline cellulose, komanso calcium stearate, anhydrous colloidal silicon dioxide, talc ndi povidone zilipo pano. Kuphatikizako kwa kanema kumakhala ndi talc, titanium dioxide, mowa wa polyvinyl, komanso polyethylene glycol. Mapiritsi okhala ndi matuza 10 zidutswa. Mu mankhwala mungagule ma CD okhala ndi mapiritsi 30.
Njira yothetsera jakisoni ndi madzi osapaka utoto, omwe amaikidwa m'milazi yamagalasi awiri. 1 ml yankho lotere lili ndi 50 mg ya pyridoxine hydrochloride, 50 mg ya thiamine hydrochloride ndi 0,5 mg wa cyanocobalamin. Zinthu zina zilipo mu yankho, makamaka lidocaine hydrochloride, benzyl mowa, sodium hydroxide solution, sodium polyphosphate, potaziyamu hexacyanoferrate III ndi madzi oyeretsedwa. Mankhwala amagulitsa mapaketi a mabotolo 5 kapena 10.
Pharmacological zimatha mankhwala
Kodi mankhwala a "Vitaxone" ndi amtundu wanji? Malangizo ogwiritsira ntchito akuwonetsa kuti mankhwalawa ali ndi phindu pa kugwira ntchito kwamanjenje. Makamaka, mavitamini a B awa ndi othandiza pamaso pa njira yotupa komanso yoipa m'mitsempha ndi minyewa. Pa Mlingo wapamwamba, zinthu izi zimathandizira kupangika kwa magazi, kusintha magazi, komanso kukhala ndi mphamvu ya analgesic.
Thiamine (Vitamini B1) amatenga nawo mbali machitidwe a metabolic. Makamaka, zimakhudza kayendedwe ka metabolic mu minofu ya mitsempha komanso kuthamanga kwa kusokonekera kwa magetsi. Ndi akusowa kwa chinthu ichi mthupi chimadziunjikira kuchuluka kwama metabolites: lactic ndi pyruvic acid.
Vitamini B6 imakhudzana ndikusinthana kwa amino acid, komanso imapereka kapangidwe kabwinobwino ka amines monga tyramine, histamine, serotonin ndi dopmin. Zosafunikanso kwambiri m'moyo ndi vitamini B12, yomwe imatenga gawo mu syntic acid acid, imapereka njira zamtundu wa metabolic m'maselo, komanso imakhudzanso mapangidwe a magazi. Mlingo wambiri, uli ndi ma analgesic katundu.
Kutulutsa mawonekedwe ndi kapangidwe kake
Njira ya Mlingo wa Vitaxone ndi yankho la makina a intramuscular (IM): madzi ofiira omveka bwino okhala ndi fungo lozungulira (2 ml mu galasi ampoules, ma ampoules 5 mu chithuza chamtundu wa polymer, 1 kapena 2 matuza okhala pamakatoni.
1 ml yankho lili:
- yogwira popanga 100% youma (anhydrous) chinthu: pyridoxine hydrochloride - 50 mg, thiamine hydrochloride - 50 mg, lidocaine hydrochloride - 10 mg, cyanocobalamin - 0,5 mg,
- excipients: sodium polyphosphate, sodium hydroxide solution 0.1 M, potaziyamu hexacyanoferrate III, mowa wa benzyl, madzi a jekeseni.
Pharmacokinetics
Mothandizidwa ndi intramuscularly, thiamine imamenyedwa mwachangu kwambiri kuchokera pamalowo jekeseni ndikulowa m'magazi (mphindi 15 pambuyo pa kuperekedwa kwa 50 mg ya Vitaxone patsiku loyamba kugwiritsa ntchito, kugwiritsidwa ntchito kwa zinthu ndi 484 ng / ml). Vitamini B1 imagawidwa mosasiyanasiyana mthupi: m'madzi am'magazi mwake mulibe kupitirira 10%, mu leukocytes imafika 15%, ndipo m'magazi ofiira - 75%. Izi zimadutsa muubongo-wamagazi ndi zotchinga zina ndipo zimapezeka mkaka wa m'mawere. Thiamine amachotseredwa kudzera mu impso mu gawo la α pambuyo pa maola 0.15 atatha kukhazikitsa, mu gawo la β pambuyo pa ola limodzi, mu gawo lofunikira kwa masiku awiri. Ma metabolites akuluakulu ndi piramidi, thiaminocarboxylic acid ndi zinthu zingapo zosadziwika za metabolic. Mwa mavitamini onse, thiamine imapangidwira mu kuchuluka kochepa. Wachikulire amakhala ndi pafupifupi 30 mg ya vitamini B1, 10% ya kuchuluka mu mawonekedwe a thiamine triphosphate, 80% mu mawonekedwe a thiamine pyrophosphate, ndi ena onse mu mawonekedwe a thiamine monophosphate.
Mothandizidwa ndi intramuscularly, pyridoxine imatengedwa mwachangu mu kayendedwe ka magazi ndikugawika mu ziwalo ndi minofu. Metabolite yake yogwira ndi pyridoxalphosphate, yopangidwa nthawi ya phosphorylation ya CH2Magulu a OH omwe ali mumalo a 5. Pafupifupi 80% Vitamini B6 limamangidwa ndi mapuloteni a plasma. Pyridoxine imagawidwa mthupi lonse, imadutsa chotchinga ndikuzindikira mkaka wa m'mawere. Thupi limayikidwa m'chiwindi ndipo limatenga nawo mbali pokhudzana ndi okosijeni, ndikupanga 4-pyridoxic acid, yomwe imatulutsidwa mu mkodzo (nthawi yayitali ya excretion ndi maola 2-5 atamwa). Thupi laumunthu limakhala ndi 40 mpaka 150 mg ya pyridoxine, ndipo kutsika kwake tsiku lililonse kumakhala pafupifupi 1.7-3.6 mg ndi kuchuluka kwa mavitamini a 2.2 mpaka 2.4%.
Pambuyo pa makonzedwe a makolo, cyanocobalamin amapanga mapuloteni a transcobalamin, omwe amatengeka mwachangu ndi m'mafupa, chiwindi, ndi ziwalo zina. Vitamini B12 obisika ndi bile ndipo amatenga nawo mbali ya matumbo-a hepatic recirculation, komanso amawoloka chotchinga.
Zizindikiro zogwiritsidwa ntchito
Malinga ndi malangizo, Vitaxone imagwiritsidwa ntchito ngati gawo la zovuta za zotsatirazi:
- kupweteka kwa neuropathic komwe kumadza chifukwa cha matenda ashuga, mowa komanso mitundu ina ya polyneuropathies,
- neuralgia ndi neuritis: trigeminal neuralgia, neuralgia wamkati, kupweteka kwamatenda a msana (lumbar ischialgia, dorsalgia, plexopathy, radicular syndrome ndikusintha kwa msana), neuritis.
Contraindication
- pachimake mtima kulephera,
- kusokonezeka kwakukulu kwa conduction pamtima,
- nthawi yokhala ndi pakati komanso yoyamwitsa chifukwa cha kuchuluka (kwa 100 mg) pa vitamini B6,
- zaka za ana
- kusalolera payekha pazinthu za Vitaxone.
Malangizo ogwiritsira ntchito Vitaxone: njira ndi mlingo
Jekeseni wa Vitaxone amathandizidwa kwambiri intramuscularly.
- kwambiri kapena / kapena kupweteka kwapweteka kwapadera: 2 ml kamodzi patsiku kwa masiku angapo (nthawi yofunikira kuti akwaniritse kuchuluka kwa mankhwalawa m'magazi a m'magazi),
- mawonekedwe ofatsa a chithokomiro, kuphatikiza pambuyo pa kuchepa kwambiri kwa ululu: 2 ml kamodzi patsiku masiku onse atatu, pakatikati pa jakisoni wamkati, mitundu yofanana ya pakamwa imayenera kutengedwa.
Kugwiritsira ntchito Vitaxone kuyenera kumayendera limodzi ndi kuwunika kwachipatala sabata iliyonse, zomwe zingathandize, ngati mkhalidwe wachipatala wasintha, kusamutsa wodwala kuti alandire mankhwala ofananawo mkati mwachangu.
Zotsatira zoyipa
Kugwiritsa ntchito Vitaxone kungayambitse kukulitsa zotsatirazi zosasangalatsa:
- Nthawi zina: thukuta lochulukirapo, tachycardia, ziphuphu, zotupa pakhungu (kuphatikizapo kuyabwa, urticaria), mphamvu ya hypersensitivity mu mawonekedwe a zidzolo, kufupika, kunjenjemera, anaphylactic, angioedema,
- osati kawirikawiri: chifukwa cha benzyl mowa wama mankhwala - hypersensitivity reaction,
- pafupipafupi sizikudziwika: kuwotcha pamalo a jakisoni,
- ena: motsutsana ndi maziko akumayambiriro kwa mankhwalawo kupita mthupi (chifukwa chakuyambitsidwa kwa tiziwalo tambiri tokhala m'magazi kapena jekeseni wamitsempha wosazindikira) kapena Mlingo wowonjezera - zomwe zimachitika, kuphatikizapo chizungulire, kusanza, chisokonezo, arrhythmia, bradycardia, kupweteka.
Mimba komanso kuyamwa
Kulimbikitsidwa Kudya Tsiku ndi Tsiku kwa Vitamini B1 mukagwiritsidwa ntchito mwa amayi apakati komanso akumiyamwa ndi 1.4-1.6 mg, ndi vitamini B6 - 2.4-2.6 mg. Kupitilira Mlingo uwu pa nthawi yovomerezeka ndizovomerezeka pokhapokha ngati pali mtundu wina wa thiamine ndi pyridoxine, popeza chitetezo cha kasitomala wa mavitaminiwa pamlingo wambiri kuposa zomwe zimafunikira tsiku lililonse sizinatsimikizidwe. Komanso Vitamini B1 ndi B6 mtima mu mkaka wa m'mawere, ndi kuchuluka kwa vitamini B6 kuchepetsa mkaka. Pazifukwa izi, kugwiritsa ntchito Vitaxone pa nthawi yoyembekezera komanso mkaka wa m`mawere ndi zovomerezeka.
Kuyanjana kwa mankhwala osokoneza bongo
Pogwiritsa ntchito nthawi yomweyo Vitaxone:
- Zomwe zili ndi sulfite zomwe zimapangitsa kuti ziwonongeke kwathunthu za thiamine, kupezeka kwa zinthu zowola za vitamini B1 itha kuyambitsa mavitamini ena mu yankho,
- levodopa akhoza kuchepetsa ake achire,
- epinephrine ndi norepinephrine, chifukwa cha kupezeka kwa lidocaine mu kapangidwe kake ka mankhwalawa, kumakulitsa chiopsezo chogwira ntchito kuchokera pansi pamtima (ngati mankhwala osokoneza bongo amaletsedwa, samaloledwa).
Kuphatikiza apo, kuyanjana ndi penicillamine, isoniazid, cyclosporine, sulfonamides ndikotheka.
Ma analogi a Vitaxon ndi awa: Hypoxene, Neurox, Vitagamm, Trigamm, Combilipen, Mexicoiprim, Mexicoidant, Mexicoidol, Cytoflavin.
Ndemanga za Vitaxone
Nthawi zambiri madokotala ndi odwala amasiya ndemanga zabwino za Vitaxone. Amatsimikizira kugwira ntchito kwake komanso chiopsezo chochepa cha zoyipa, komabe, amalangizidwa kuti azigwiritsa ntchito mankhwalawa pokhapokha atakumana ndi katswiri.Amachotsa kupweteka kumbuyo (mwachitsanzo, ndi osteochondrosis) ndi njira yotupa m'matumbo a minyewa ndi minofu, imagwira ntchito bwino ndikuthandizira kuuma molumikizana. Nthawi zina mankhwalawa amadziwitsidwa ndi gastroenterologists chifukwa cha kutupa m'matumbo. Komabe, jakisoni wa Vitaxone amatha kupweteka kwambiri.
Momwe mungagwiritsire ntchito Vitaxone?
Mankhwala Vitaxone - mtundu watsopano wa mavitamini B, omwe amatchedwa neurotropic, machitidwe awo ali ndi njira yosankha. Mankhwalawa ali ndi mphamvu yokhudzana ndi kugwira ntchito kwa mtima wamanjenje (ubongo) komanso ku zotumphukira (ma nerve endings, node).
Muzochita zamankhwala, matenda omwe amachitika ndi kufooka kwamphamvu kwa mavitamini B, zomwe sizipangidwa ndi thupi laumunthu ndipo zimangobwera ndi zakudya zam'mera kapena zopangidwa ndi nyama.
Chakudya chamafuta kwambiri, chizolowezi chomwa mowa komanso fodya, mankhwala osatha, matenda osachiritsika amatsatiridwa ndi kutsika kwakukuru kwa vitamini B m'thupi, zomwe zimayambitsa kusokonezeka kwamanjenje.
- Kufotokozera zamphamvu za vitamini vitamini Vitaxone
- Kuphatikizika, mawonekedwe a kumasulidwa kwa mankhwalawa
- Zisonyezero zakugwiritsa ntchito yankho ndi mapiritsi
- Malangizo ogwiritsira ntchito
- Zochita Zosiyanasiyana Mapiritsi ndi Majekesi
- Contraindication
- Zowonjezera zowgwiritsira ntchito
- Ndemanga
Zizindikiro zake za matendawa ndi chifukwa chiyani ndiyenera kumwa mankhwala a multivitamin Vitaxone? Malinga ndi madotolo, mankhwalawa adatsimikizira okha mu chithandizo chamankhwala omwe amayamba chifukwa cha zinthu zotsatirazi:
- Kusokonezeka kwa kayendedwe ka magazi muubongo komwe kumachitika chifukwa chosowa vitamini B, zomwe zimayambitsa kukayika kwa minofu ndi mafupa.
- Matenda amkati mwa zotumphukira za mitsempha yomwe imayambitsidwa ndi njira zopweteka zotupa ndipo zimagwirizanitsidwa ndi kuphwanya kapangidwe ka mafupa amitsempha.
- Kutupa kwa mbali zina zam'mitsempha yam'mimba kumadera akutali a mikono ndi miyendo, ndikuyambitsa kuwonekera kwawo pang'ono, mitsempha ya mitsempha ya mitsempha, ziwindi zina.
Vitaxone imakhala ndi ma multivitamini mu milingo yayikulu, yomwe imakhudza bwino kukula ndi mapangidwe a maselo atsopano amitsempha, imabwezeretsa makina awo operewera m'mitsempha yamitsempha, imathandizira kufalikira kwa magazi mu maselo aubongo, ndipo imakhudzanso ma analgesic.
Kufotokozera zamphamvu za vitamini vitamini Vitaxone
Mankhwala a neurotropic ali ndi mavitamini atatu ofunikira m'thupi la munthu:
- Thiamine kapena Vitamini B1 amatenga kagayidwe kazakudya, imathandizira kayendedwe kazinthu zobweretsa ubongo ku maselo amitsempha. Kuperewera kwa vitaminiyu kumabweretsa kudzikundikira kwa amino acid owopsa, zomwe zimayambitsa kusokonezeka kwamanjenje.
- Pyridoxine, aka Vitamini B6, imathandizira kupanga michere yogwira michere yogwiritsira ntchito michere yofunika m'thupi. Amatchedwa vitamini. Pamodzi ndi mavitamini ena a B, amalepheretsa matenda amitsempha yama ziwongo, amateteza thupi ku matenda, amasunga mphamvu ya mahomoni, ndikuwongolera magwiridwe antchito am'maganizo.
- Madzi a Vitamini B12 (cyanocobalamin) imayang'anira ntchito yopanga magazi, imalimbikitsa kupangidwa kwa maselo ofiira, imagwira nawo gawo lomwe limasokoneza mapuloteni osavuta amino acid, imasinthasintha kuchuluka kwa hemoglobin m'magazi, ndikuwonetsa ntchito ya analgesic.
Chifukwa cha kuphatikiza kumeneku, Vitaxone ya mankhwala imapangitsa kuti manjenjenje azigwira ntchito moyenera, kukhazikika pa ntchito yake, komanso kumasula mtima wachisangalalo.
Kuphatikizika, mawonekedwe a kumasulidwa kwa mankhwalawa
Pamsika wamankhwala, amaimiridwa ndi mapiritsi amkamwa pakamwa ndi yankho la jakisoni.
- Mapiritsi wokutidwa ndi chipolopolo, chokhala ndi mbali zokulirapo, kuzungulira, zoyera, zodzala ndi matuza a zidutswa 10 chimodzi. Piritsi limaphatikizira: benfotiamine 100 mg yogwira popanga vitamini B1 ndi pyridoxine 100 mg (vitamini B6), yomwe ndiyo chinthu chachikulu chogwira ntchito. Zina mwa mapiritsi zimathandizira kuti thupi lizitulutsa mwachangu komanso mosatetezeka.
- Yankho la jakisoni kupezeka m'magalasi abuluu a bulauni, mu 2 ml yamadzi amadzi oyera okhala ndi tint yofiyira. Atadzaza m'matumba, 5 kapena 10 ampoules, omizidwa m'mbale ndi maselo. Zinthu zosungunuka zam'madzi mu 1 ampoule: 50 mg ya mavitamini B1, B6, B12 (thiamine hydrochloride, pyridoxine, cyanocobalamin). Zosakaniza zingapo zomwe zimawonjezeredwa ku yankho zimathandizira kugawa yunifolomu ya zinthu zogwira ntchito mthupi.
Mlingo
Mapiritsi okhala ndi mafilimu
Piritsi limodzi lili
ntchito yogwira - benfotiamine 100 mg malinga ndi 100% youma, pyridoxine hydrochloride 100 mg malinga ndi 100% youma,
zokopa: microcrystalline cellulose (101) ndi (102), wowuma chimanga, povidone (K 29/32), calcium stearate, talc, silicon dioxide anhydrous colloidal dioxide (Aerosil 200),
kapangidwe ka chipolopolo Opadry II 85 F 18422 Choyera: mowa wa polyvinyl, polyethylene glycol, talc, titanium dioxide (E 171).
Mapiritsi oyera kapena pafupifupi oyera, ozungulira mawonekedwe, okhala ndi biconvex pamwamba, filimu yokutira
Malangizo ogwiritsira ntchito
The pakamwa mawonekedwe a mankhwala zotchulidwa piritsi 1 katatu patsiku. Onetsetsani kuti mumamwa madzi ambiri.
Jakisoni wa "Vitaxone", amagwiritsidwa ntchito pothandiza kuchepetsa ululu waukulu. Inayambitsidwa mwamphamvu mu 2 ml kamodzi patsiku. Mlingo umachepetsedwa pang'onopang'ono mpaka 2 ml patsiku, ndikupanga kupuma kwa tsiku limodzi pakati pa jakisoni.
Mankhwalawa amasankhidwa masiku 30. Dokotala wokhayo ndi okhayo amene angakulitse nthawi ya mankhwalawo kapena kupereka mankhwala kuti asadzayambenso. Ndikofunika kukumbukira kuti musanagwiritse ntchito mankhwala omwe ali ndi lidocaine, kuyesedwa kwa munthu payekha kuyenera kuchitidwa.
Wobayira jakisoni
- Hypersensitivity,
- yoyamwitsa
- decompensated pachimake kulephera kwa mtima,
- kukwiya zamkati mtima pachimake
- mimba
- psoriasis,
- zaka za ana.
Zotsatira zoyipa
Mankhwalawa amadziwika bwino, koma ngati pakhale mankhwala osokoneza bongo kapena osalolera, zotheka zimachitika:
- urticaria kapena mavuto ena azakhungu,
- ziphuphu.
- kukokana
- kukomoka mtima,
- chizungulire
- thukuta kwambiri
- kupuma movutikira kapena kufupika kwa mpweya
- pachimake thupi lawo siligwirizana, zomwe zingayambitse anaphylactic mantha.
Chizindikiro chimodzi chikayamba kuchitika, siyani kumwa mankhwalawo ndipo pitani kuchipatala msanga.
Zochita Zosiyanasiyana Mapiritsi ndi Majekesi
M'mawunikidwe awo, madokotala amagogomezera kuti mavitamini onse a B ndi achilengedwe kwa anthu ndipo zovuta zomwe zimachitika chifukwa chotenga Vitaxone ndizochepa, ndizosowa komanso chifukwa cha mawonekedwe amunthu.
- Kumwa mapiritsi kumatha kuyambitsa zotupa pakhungu, limodzi ndi kuyabwa pang'ono. Mankhwalawa amalowetsedwa m'matumbo ang'onoang'ono, kotero kuti zovuta zake zina zimatha: kupweteka kwapweteka m'mimba, kumverera mseru, m'mimba.
- Kubaya jekeseni mwachangu kumayambitsa zotsatirazi zosakhalitsa: chizungulire, kulephera kwa mtima, kulefuka, komanso kutuluka thukuta. Nthawi zina, thupi lawo siligwirizana zimatheka: zotupa, kuyatsidwa khungu, urticaria. Patsamba la jakisoni, edema nthawi zina imachitika, redness imawoneka ndi mafomu olimbitsa minofu.
Kugwiritsa ntchito mapiritsi nthawi yayitali kapena njira zake ndi jakisoni, nthawi zina, kumapangitsa wodwalayo kukhathamiritsa thupi ndi mankhwala a vitamini. Pali chizungulire chachikulu, kusanza, kupsinjika, arrhythmia, kutaya chikumbumtima. Muyenera kuyimbira foni dokotala ndikupereka chithandizo kwa wodwala woyamba: chitani zam'mimba ndikupatsa anti-kuledzera wothandizila, enterosorbent.
Zizindikiro za kumwa mankhwalawa
Kodi Vitaxone imaperekedwa kwa odwala nthawi ziti? Malangizowo akuwonetsa kuti mitundu ya mapulogalamu pano ndi yotakata. Mankhwala amagwiritsidwa ntchito pochizira matenda osiyanasiyana amanjenje. Makamaka, imathandizira neuralgia, neuritis, polyneuropathies, komanso zotupa zam'mimba komanso zowopsa zamanjenje. Zisonyezero zamagwiritsidwe ntchito ndizovuta zomwe zimachitika chifukwa cha kusowa kwambiri kwa mavitamini a B. Mankhwalawa ndi gawo limodzi la mankhwalawa kufooka kwamanja, myalgia, matenda ashuga komanso mowa mwauchidakwa. Imagwiritsidwanso ntchito kupumula radicular syndrome ndi kusapeza bwino ndi shingles.
Mapiritsi a Vitaxone, malangizo ogwiritsira ntchito
Mapiritsiwo akuwonetsedwa pakumwa pakamwa (pakamwa) ndi madzi.
Mlingo wovomerezeka tsiku lililonse ndi piritsi limodzi m'mitundu itatu yogawika.
Mukumva kupweteka kwambiri komanso m'malo ovuta kwambiri, kuti muwonjezere msanga plasma ya mankhwalawa, yankho la jakisoni limagwiritsidwa ntchito. Kupitiliza mankhwala, monga lamulo, kumafunikira kudya piritsi limodzi kwa masiku 30.
Mankhwala "Vitaxone": malangizo ntchito (mapiritsi)
Masiku ano, odwala ambiri amathandizidwa ndi mankhwalawa. Nanga mutenge bwanji mankhwalawa "Vitaxone"? Mapiritsi amatha kuledzera mosasamala chakudyacho, koma onetsetsani kuti mumamwa madzi oyera ambiri. Monga lamulo, madokotala amalimbikitsa kutenga 1 tabu. Katatu patsiku. Kutalika kwa chithandizo kumatsimikiziridwa payekhapazokha. Komabe, nthawi zambiri njira yochizira imatenga pafupifupi mwezi.
Ndizofunikira kudziwa kuti muzovuta kwambiri, pakamwa pobayira jekeseni ndikololedwa. Njira yofananira imalimbikitsidwa ngati mukufunikira mwachangu komanso mwachangu kuwonjezera ndende yogwira mankhwala omwe ali m'magazi. Zizindikiro zikayamba kuchepa, wodwalayo amapatsidwa pang'onopang'ono pamapiritsi.
Bongo
Ndi mankhwala osokoneza bongo a mtundu uliwonse wa Vitaxone, kuwonjezereka kwa zotsatirapo za mankhwalawa. chizungulire, arrhythmianseru bradycardia, kukokanakuchuluka thukuta.
Chithandizo cha chizindikiro chikuwonetsedwa.
Kuchita
Akaphatikizidwa ndi mankhwala, kuphatikizapo Levodopa, zotumphukira zake decarboxylation zimawonjezeka ndipo kugwira ntchito kwa antiparkinsonia kumachepa.
Benfotiamine yosagwirizana ndi mankhwala a alkaline ndi othandizira oxidizing: iron-ammonium citrate, ayodiniMercury mankhwala enaake kaboni, tannic acid, acetate, komanso ndi Riboflavin, Phenobarbital, Benzylpenicillinmetabisulfite ndi shuga, popeza pamaso pawo am'peza kusachita.
Ndi kuwonjezeka kwa pH yoposa 3 mfundo thiamine kutaya ntchito.
Kukonzekera mkuwa imathamanga cleavage benfotiamine.
Mukamayanjana ndi mayankho sulfates kuwola kwathunthu kumachitika thiamine.
Malangizo apadera
Mosamala kwambiri, mapiritsi a Vitaxone amayenera kuperekedwa kwa odwala omwe ali ndi vuto lalikulu komanso oopsa mtima wowonda.
Kulembera mapiritsi kwa odwala omwe ali ndi tsankhogalactosemalabsorption galactose ndi shugakuchepa mkanda.
Odwala Hypersensitivitykuyambitsa Vitamini B12 intramuscularly kungayambitse anaphylactoid zimachitika.
- Hypoxene,
- Vitagamm,
- Kombilipen,
- Montidant,
- Mexicoiprim,
- Mexicoidol,
- Neurox,
- Trigamma,
- Cytoflavin etc.
- Combigamma,
- Milgamma,
- Neurobion,
- Neurolek,
- Neurorubin,
- Neuromax,
- Neovitam,
- Neurobion etc.
Palibe zokumana nazo ndi mapiritsi a Vitaxone muubwana.
Kugwiritsa ntchito jakisoni yankho la mankhwala sikuletsedwa.
Zowonjezera zowgwiritsira ntchito
Vitaxone sangaphatikizidwe ndi ma multivitamini ena.
Ndi chithandizo chamankhwala, kuyanjana kwa mankhwala ena omwe ali ndi Vitaxone yokonzekera mavitamini kuyenera kuganiziridwanso kuti muchepetse kuwonongeka kwa mankhwala ake.
Jakisoni sayenera kusakanikirana ndi kutumizidwa nthawi yomweyo ndi mankhwala ena.
Eni magalimoto kapena othandizira magalimoto amaloledwa kugwiritsa ntchito Vitaxone pochiritsa.
Mu pharmacy, Vitaxone ya neurotropic yokonza ikupezeka pamankhwala. Mtengo wa mapiritsi ndi jakisoni umapezeka kwa wogula.
Njira yogwiritsira ntchito
Mankhwala Vitaxon jekeseni pang'onopang'ono kulowa mu minofu.
Woopsa matenda ndi ululu waukulu, kuti muwonjezere mavitamini m'magazi, 2 ml yankho limayikidwa intramuscularly 1 nthawi patsiku. Mochulukitsa atacheperachepera matendawa, 2 ml amatchulidwa 2 mpaka 3 pa sabata.
Njira ya mankhwala kumatenga pafupifupi mwezi umodzi.
Zosankha
:
Jakisoni wambiri wa vitamini B12 angayambitse anaphylactoid zimachitikira odwala hypersensitivity.
Kutha kusinthitsa kuchuluka kwa zochita mukamayendetsa kapena kugwiritsa ntchito njira zina. Sizikhudzanso kuchuluka kwa magalimoto akamayendetsa magalimoto ndikugwiritsa ntchito njira zina. Odwala chizungulire pambuyo kukhazikitsa mankhwala sayenera kuyendetsa magalimoto kapena kugwira ntchito ndi zina.
Mankhwala "Vitaxone" (jakisoni): malangizo ogwiritsira ntchito
Mwachilengedwe, ndi dokotala yekhayo amene angadziwe mankhwala ndi kudziwa mlingo woyenera kwambiri - malangizowo ali ndi malingaliro onse. Ndiye momwe mungagwiritsire ntchito mankhwalawa? Yankho limagulitsidwa lokonzeka, ndiye apa mukungofunikira kutsatira malamulo aukhondo wamba a jakisoni. Jakisoni amachitidwa kudzera m'mitsempha.
Pa ululu waukulu, mlingo womwe umalimbikitsidwa ndi 2 ml ya yankho (imodzi yokwanira) kamodzi patsiku. Muzocheperachepera, kuchuluka kwa mankhwala omwe amathandizidwa amatha kuchepetsedwa - jakisoni amaperekedwa kamodzi masiku awiri.
Kodi pali zotsutsana?
Anthu ambiri ali ndi chidwi ndi funso loti Vitaxone ingatengedwe pamagulu onse a odwala. Malangizowa akuwonetsa kuti palinso ma contraindication pochiritsa, ngakhale alipo ambiri a iwo. Poyamba, ndikofunikira kunena kuti mankhwalawa ali ndi zoletsa zina - sanakhazikitse odwala. Kuphatikiza apo, ma contraindication amaphatikizanso kukhudzidwa kwazinthu zilizonse zomwe zimapangidwa, kotero onetsetsani kuti mumadziwa bwino mawonekedwe ake musanayambe kugwiritsa ntchito.
Mankhwala sangathe kumwedwa ndi matenda ena ammimba, makamaka pachimake matenda a mtima, komanso mawonekedwe owopsa a mtima wosakhazikika. Zotsutsana zina zimaphatikizapo psoriasis.
Tiyeneranso kulankhula za kugwiritsa ntchito mankhwalawa panthawi yapakati. Kugwiritsa ntchito mankhwala panthawiyi ndizoletsedwa. Nthawi zina, adotolo atha kukulemberani mapiritsi, koma muyenera kumwa mosamalitsa komanso pokhapokha ngati phindu lomwe likuyembekezeka ku thupi la mzimayi limapitilira zovuta zomwe zingavulaze mwana wosabadwayo.
Zotheka kukhala zovuta komanso zoyipa
Ndi zovuta ziti zomwe mankhwalawa "Vitaxone" angadzetse? Malangizo ogwiritsira ntchito akuwonetsa kuti kupezeka kwa zotsatira zoyipa sikujambulidwa kwenikweni. Komabe, zovuta ndizotheka, choncho muyenera kuzolowera mndandanda wawo.
Mapiritsi nthawi zina amayambitsa zina za dyspeptic, mwachitsanzo, kupweteka kwam'mimba, mseru, komanso vuto la chopondapo. Mwina chitukuko cha thupi lawo siligwirizana, limodzi ndi kuyabwa, totupa, khungu redness, urticaria. Ndi chidwi chochulukirapo, kugwedeza kwa anaphylactic ndikotheka.
Kodi Vitaxone imabweretsa mavuto enanso otani? Kutemera kungapangitse kusokonezeka kwakanthawi, kuphatikiza chizungulire, mseru, kukomoka, ndi thukuta kwambiri. Edema ya Quincke, zovuta kupuma komanso mawonekedwe a kugwidwa ndizofala kwambiri.
Kodi bongo ndizotheka? Zizindikiro ndi Chithandizo
Kodi pali milandu ya bongo ndi Vitaxone? Malangizo ogwiritsira ntchito akuwonetsa kuti zofanana ndizotheka. Kumbali ina, kafukufuku wa mawerengero amatsimikizira kuti mankhwala osokoneza bongo amakono ndi osowa kwambiri ndipo nthawi zambiri amagwirizanitsidwa ndi kugwiritsidwa ntchito kwa nthawi yayitali.
Monga lamulo, zinthu zoterezi zimayendera limodzi ndi kukokoloka kwa mavuto. Odwala ena amadandaula ndi nseru, zomwe nthawi zambiri zimasanduka kusanza. Chizungulire chachikulu chingachitike. Zizindikiro zake zimaphatikizira kupweteka kwa minofu, komanso bradycardia. Nthawi zambiri kumakhala kuchepa kwa kuthamanga kwa magazi, thukuta limachulukirachulukira. Woopsa milandu, bongo ndi limodzi chopinga wa mantha dongosolo, kupuma kumangidwa.
Munthu wokhala ndi zizindikiro zofananira ayenera kuwonetsedwa dokotala. Kutupa kwam'mimba ndi kugwiritsa ntchito ma sorbents (mwachitsanzo, kaboni yokhazikitsidwa) ndikofunikira pokhapokha ngati mankhwalawo adatengedwa posachedwa ndipo sanayende nawo pakukodwa m'mimba. Kuperekanso chithandizo kumalimbana ndikuchotsa zizndikiro ndipo zimatengera chithunzi cha chipatala. Mwachitsanzo, pamaso pa kugwidwa, ma anticonvulsants amalembedwa kwa odwala, ndipo akapuma amasiya, makulitsidwe ndi mpweya wokwanira amapatsidwa.
Kodi mankhwalawo ndi angati?
Inde, nkhani ya mtengo ndiyofunika kwa wodwala aliyense. Koma ndikofunikira kumvetsetsa kuti kuchuluka komwe mudzalipira mankhwalawa kumatengera zinthu zambiri, kuphatikiza wopanga, ndondomeko ya zachuma zamankhwala, etc. Kodi mankhwala a Vitaxone angatenge ndalama zingati?
Mtengo wa mapiritsi olongedza (zidutswa 30) umachokera ku 200 mpaka 300 rubles. Koma kuyika ma ampoules asanu a yankho kumawononga ndalama pafupifupi ma ruble 150-250. Vomerezani, poyerekeza ndi mankhwala ena, mtengo wa mankhwalawa ndi wokwera mtengo.
Kodi pali ma fanizo othandiza?
Odwala ambiri omwe adalembedwa mankhwalawa ali ndi chidwi chofuna kudziwa zambiri za Vitaxone. Mapiritsi, malangizo ogwiritsira ntchito, kupezeka kwa ma contraindication, etc. - izi ndizofunikira kwambiri. Koma nthawi zina munthu samakhala ndi mwayi woti amwe mankhwalawa (mwachitsanzo, ndi hypersensitivity kapena kusowa kwa mankhwala m'mafakitena). Kodi ndizotheka kusintha m'malo mwake ndi china chake?
Mwachilengedwe, msika wamakono wamankhwala umapereka mankhwala ambiri omwe ali ndi katundu wofanana. Mwachitsanzo, ndi neuralgia, ndizovomerezeka kugwiritsa ntchito mankhwala monga Vipratox, Neurobeks, Neurorubin, Neuromultivit, Nerviplex ndi ena ambiri. Ndipo musaiwale kuti zilonda zitha kuchotsedwa ndimankhwala oyenera osagwiritsa ntchito mankhwala a anti-yotupa, kuphatikiza Nurofen ndi Ibuprofen. Komanso, musayang'ane nokha analogue nokha - adokotala azikusankhirani malo omwe angakukonzereni.
Ndemanga za odwala ndi madokotala
Inde, anthu ambiri ali ndi chidwi ndi mafunso okhudza Vitaxone kwenikweni. Malangizo, mtengo, zikuwonetsa ndi contraindication ndizochita zazikulu. Komabe, ndikofunikira kudziwa malingaliro a madokotala pankhaniyi.
Akatswiri ambiri amakhulupirira kuti mankhwalawo amagwiradi ntchito yake, amachepetsa ululu, amatithandizanso kugwira ntchito kwamanjenje, ndipo amakwaniritsa kuchepa kwa mavitamini. Kuphatikiza apo, mankhwalawa ali ndi zotsutsana zochepa, ndipo zovuta zake ndizosowa kwambiri.
Wodwalayo amayankhanso mosamala mankhwalawa. Zotsatira zabwino zitha kudziwika kale kuyambira masiku oyamba ovomerezeka. Kuphatikiza apo, chiwopsezo chaumoyo pankhaniyi ndi chochepa, popeza mavitamini a B ndi zinthu zachilengedwe zathupi. Chokhacho chofunikira kukumbukira: muyenera kutsatira malangizo a dokotala mosamala. Ndipo, zoona, mtengo wotsika mtengo ndi mwayi wina wa mankhwalawa.
Mawonekedwe a phwando
Mankhwala samakhudza kuchuluka kwa zomwe akuchita. Zololedwa kwa anthu omwe amayendetsa magalimoto.
Mankhwala amathandizidwa mosamala kwa odwala omwe ali ndi mbiri ya kulephera kwa mtima, mu gawo la kuwonongeka. Ndi kuyambitsa jekeseni, kuyang'anira pafupipafupi ogwira ntchito azachipatala pazokhudza wodwalayo kumafunikira.
Vitaxone imasungidwa kwa miyezi 24. Pambuyo pa nthawi yomwe yatchulidwa, mankhwalawo amaletsedwa. Onetsetsani kuti mwayeretsa malowa m'malo amdima omwe ana sangathe kuwapeza. Kutentha kosasungirako kuposa 15 ° C.
Ndemanga pa "Vitaxone"
Pafupifupi mayankho onse okumwa mankhwalawo ndi abwino. Odwala amawona kuchuluka kwa mankhwalawa komanso mtengo wake wotsika mtengo.
"Vitaxon" imathandizira mwachangu ndi zovuta zochizira matenda amanjenje ndi musculoskeletal system.
Choipa chachikulu cha jakisoni ndi kupweteka kwa njirayi, koma pambuyo pa jekeseni woyamba, mphamvu zabwino zimadziwika.
Ngati thupi lonselo likuchitika, zizindikiro zonse zimazimiririka ndi kuchepa kwa mulingo.
Mankhwala amakwaniritsa zonse zofunikira zomwe zikufotokozedwa m'malangizo.
"Vitaxone" ndi chida chothandiza kwambiri chomwe chingathandize kuthana ndi unyinji wa matenda osasangalatsa ndikuchotsa zomverera zopweteka.