Omacor: malangizo ogwiritsira ntchito, ma fanizo ndi ndemanga, mitengo yamafesi ku Russia

Omacor ndiye lipid-kutsitsa mankhwala omwe mankhusu ake ali mgululi omega-3 polyunsaturated mafuta acids (eicosapentaenoic ndi maidosahexaenoic) ndipo ndizofunikira (zofunika) mafuta acids.

Omacor amathandizira kuchepetsa milingo triglycerides chifukwa chochepetsera VLDLkomanso kuchepetsa kaphatikizidwe thromboxane A2 ndi kutalikitsa kwa nthawi magazi, yomwe imawonetsedwa ndi mphamvu yake yogwira HERE ndi makulidwe. Panalibe phindu lililonse la mankhwalawo pazinthu zina zophatikizana.

Chifukwa choletsa kuyesa kwa EPA ndi DHA, kuchedwa kwakaphatikizidwe kumawonedwa hepatic triglycerideszikubweretsa kuchepa kwa kupsinjika kwawo, zomwe zimathandizira kuwonjezeka kwa β-oxidation kwamafuta acids peroxisome (kuchepetsa kuchuluka kwamafuta amafuta achilengedwe oyenera kuphatikizika triglycerides) Kuponderezedwa kwa njira za kaphatikizidwe kameneka kumakondwera kuchepa kwa mulingo wa VLDL. Odwala ena akuvutika hypertriglyceridemia, Chithandizo cha Omacor chimawonjezera milingo yambiri LDL cholesterolpomwe milingo ikukula HDL ndi yocheperako komanso yocheperako pang'ono poyerekeza ndi chithandizo mafupa.

Kutalika lipid-kutsitsa Kugwiritsa ntchito kwa mankhwala Omacor kwa miyezi yopitilira 12 sikunaphunzire. Magawo ofufuzira samapereka umboni wotsimikizika wa chiopsezo chochepetsedwa cha mapangidwe Matenda a mtima wa Ischemic ndi kuchepa kwa ndende triglycerides.

Malinga ndi zotsatira za mayeso azachipatala, kudya kwa pakamwa tsiku lililonse kwa 1000 mg ya Omacor kwa zaka 3.5 kunapangitsa kutsika kwakukulu kwa chisonyezo chophatikiza, kuphatikiza sitiroko, myocardial infaration komanso kufa mwambiri kwa odwala ochokera kuzifukwa zonse.

Pochita izi, komanso mukamaliza kuyamwaomega 3 mafuta acidsm'matumbo ang'onoang'ono, njira zazikuluzikulu zitatu zosinthira zawo zimawonedwa:

• kutumiza koyamba kwa mafuta achilengedwe m'chiwindi, komwe amaphatikizidwa m'magulu osiyanasiyana lipoprotein ndi kupatsanso chiwopsezo lipid masheya
• m'malo phospholipids ma cell membrane lipoprotein phospholipids ndi kugwira ntchito kwamafuta acids ngati othandizira ena osiyanasiyana eicosanoids,
• oxidizing mafuta ochulukirapo kuti akwaniritse zosowa zamagetsi.

Zizindikiro zogwiritsidwa ntchito

Zisonyezero zogwiritsira ntchito Omacor zikuphatikiza:

• yachiwiri prophylaxis wa womupeza myocardial infaration (munthawi ya mankhwala ndi zovuta zina mankhwala muzochitika zotere: ACE zoletsa, antiplatelet agents, ma statins, opanga beta,
• amkati hypertriglyceridemiamonga kuwonjezera pa zakudya mankhwala chifukwa cha kuchepa kwake: mu monotherapy ndi mtundu IV matenda komanso ma statins ndi mtundu IIb / III matenda (pamene ndende triglycerides osungidwa pamalo okwera).

Contraindication

Kusankhidwa kwa Omacor sikuvomerezeka ndi:

• mimba
• zanga zokha Hypersensitivity kuti omega-3-triglycerides,
• yoyamwitsa
• zakunja hypertriglyceridemia (Ndikuyimira hyperchilomicronemia).

Kugwiritsa ntchito Omacor mosamalitsa ndikuloledwa:

• ntchito pakamwa anticoagulants ndi michere,
• ofotokozedwa matenda a kwa chiwindi ntchito,
• kuchita opareshonindi chithandizo kuvulala kwambiri (chifukwa chakuwonjezera nthawi magazi),
• pa zaka 18 (chifukwa chosadziwika bwino pakubwezeretsa mankhwala kumeneku komanso kugwira ntchito kwake), komanso okalamba (pambuyo pa zaka 70).

Zotsatira zoyipa

Panthawi ya chithandizo ndi Omacor, ndimawonekedwe osiyana siyana (nthawi zambiri samadziwika), adadziwika:

• dyspeptic zovuta
• kutsitsa magazi,
• nseru,
• chitukuko gastroenteritis,
• mphuno yowuma
• zochitika za chidwi chamunthu,
• zam'mimba thirakiti,
• hyperglycemia,
• kuyaka,
• chizungulire,
• mawonekedwe a zakuda,
• kukoma kosokoneza (dysgeusia),
• zilonda zam'mimba
• mutu,
• kapangidwe ka gastritis,
• urticaria,
• kuphwanya kwa chiwindi ntchito,
• Kutaya magazi kwa GI.

Popanga kafukufuku, sizinkachitika kawirikawiri:

• kuchuluka pazambiri lactate dehydrogenase ndi maselo oyeramagazi,
• kuchuluka kwapakati transaminase (ALT, AST).

Mwapadera, zolembedwa:

• kuchuluka kwa odwala insulin,
• kuchuluka kwa ntchito michere ya chiwindi,
• zotupa pakhungu
• maphunziro rosacea,
• redness/erythema,
• zochitika urticaria m'malo mwa chifuwa, mapewa ndi khosi,
• kupweteka kwa minofu,
• kuchuluka kwa magazi creatine phosphokinase,
• kunenepa.

Omacor, malangizo ogwiritsira ntchito (Njira ndi Mlingo)

Malangizo ogwiritsira ntchito Omacor akutsimikizira kukonzekera kwa pakamwa (pakamwa) kwa makapisozi a mankhwala limodzi ndi kudya.

Chifukwa chachiwiri kupewa myocardial infaration Kudya kwa tsiku ndi tsiku kwa kapisozi yoyamba ya mankhwalawa kumasonyezedwa kwa nthawi yomwe dokotala amakupatsani (kutengera mkhalidwewo).

At hypertriglyceridemia Poyamba, ndikulimbikitsidwa kutenga makapisozi awiri mu maola 24, ndikuthekera kochulukitsa tsiku lililonse la mkazi wamasiye (makapu anayi). Kutalika kwa mankhwalawa kumatsimikiziridwa ndi dokotala.

Kuchita

Makamaka a omacor ndi michere osavomerezeka.

Kugwiritsa ntchito Omacor kuphatikiza Warfarin sanapereke chilichonse hemorrhagic zochitika zoyipa. Komabe, pankhani yophatikiza mankhwalawa kapena kusiya kwa mankhwala a Omacor, chizindikirocho chikuyenera kuyang'aniridwa.prothrombin nthawi.

Kugwirizana pakamwa anticoagulants kumaonjezera ngozi ya magazi ndi nthawi yawo.

Malangizo apadera

Chifukwa cha kuchuluka kwapakati pakutalika kwa magazi muyezo wa 4 makapisozi a Omacor patsiku, odwala omwe alimankhwala anticoagulant, ndipo ngati pangafunike sinthani anticoagulants. Malangizowa samatengera kuyenera kwawongolera kuzisonyezo zina kwa odwala otere.

Kukongola kwa nthawi magaziodwala omwe ali pachiwopsezo chachikulu cha kutulutsa magazi (kuphatikizapo opaleshoni kapena kuvulala kwambiri).

Kafukufuku yemwe adakhalapo wachiwiri kwachiwiri hypertriglyceridemia (makamaka ponena za osalamulirika matenda ashuga) ndi ochepa. Palibe kachitidwe kachipatala kogwiritsa ntchito Omacor pochiritsira hypertriglyceridemia mukutenga michere.

Mukamapereka chithandizo pogwiritsa ntchito Omacor, kuwonjezeka kwapakati pa ntchito kumaloledwa chiwindi transaminase.

Pankhani ya wodwala wapezeka kuphwanya kwa chiwindi ntchito (makamaka ndi kudya kwa mapiritsi a 4 a tsiku ndi tsiku a makapisozi) amafunikira kuyang'anira ntchito ya chiwindi pafupipafupi (kuwunika ma ALT ndi milingo ya ACT).

Zambiri zodalirika za zotsatira za Omacor muubwana (mpaka zaka 18) ndi okalamba (zaka 70), komanso okhudza odwala omwe ali ndi matenda a chiwindikulibe.

Ikawonedwa aimpso Kusintha kwa Mlingo sikofunikira.

Omacor Analogs

Zofananira za mankhwalawa ndi:

Mtengo wa Omacor analogues umasiyana kwambiri ndipo zimatengera zinthu zambiri zomwe zimapanga mtengo wamankhwala ena (kuphatikiza wopanga, kuchuluka kwa magawo, mawonekedwe amamasulidwe, ndi zina). Mwachitsanzo, makapisozi 60 Vitrum Cardio Omega-3 zitha kugulidwa pafupifupi ma ruble 1100, ndi mapiritsi 60 Tribestan - kwa ma ruble 2000.

Omacor ndi oletsedwa kugwiritsa ntchito ana osakwana zaka 18.

Ndemanga za Omacore

Kutsatira ndemanga za Omacor pamaforamu, munthu akhoza kupeza malingaliro otsutsana kwathunthu ndi odwala omwe amawalandira, kuyambira kwa abwino kwambiri, kukambirana za kufunikira kwakukulu ndi chitetezo chogwiritsa ntchito mankhwalawa, ndikutha ndi opanda pake, ndikuyika mankhwalawa ngati osathandiza konse.

Kuunikira kwa cholinga chakufotokozera othandizira oterewa kumatha kuganiziridwa ngati lingaliro la akatswiri omwe safuna kugulitsa kwambiri Omacor. Mayankho a akatswiri a mtima pankhaniyi amatsikira ku chipembedzo chimodzi chomwe chithandiziro chanthawi yomweyoMafuta a nsomba palibe wotsika kuposa Omakor.

Zotsatira za pharmacological

Wothandizira antihypertensive. Ndi block-non peptide angiotensin II receptor blocker. Ili ndi kusankha kwapamwamba komanso kulumikizana kwa receptors a mtundu wa AT1 (ndi kutenga nawo gawo komwe zotsatira zazikulu za angiotensin II zimadziwika). Potseka ma receptor awa, Losacor imalepheretsa ndikuchotsa mphamvu ya vasoconstrictor ya angiotensin II, mphamvu yake yotsitsimutsa ya secretion ya aldosterone ndi gren adrenal komanso zina zina za angiotensin II. Amadziwika ndi zochita zazitali (maola 24 kapena kupitilira), chifukwa cha kupangika kwa metabolite yake yogwira.

Ndemanga za madotolo zokhudza omacor

Mtundu wa PUFA womwe umafunsidwa ndiwopadera kuti ukwaniritse zosowa za thupi makamaka khazikika.

Ndili ndi ubale wovuta ndi mankhwalawa. Zikuwonekeratu kuti ma PUFA mu mawonekedwe awa amatengeka bwino, koma ngati izi zili ndi tanthauzo lachipatala sizikudziwika bwinobwino. Chomwe ndimaganiza ndichakuti supuni ya mafuta a azitona patsiku imatha kukhala yopindulitsa kuposa kudya kwa Omacor nthawi zonse. Tsoka ilo, maphunziro azachipatala nawonso samatsimikizira kufunika kwa kupulumuka kwa wodwala. Komabe, zitha kukhala zofunikira mu zovuta zina zamagetsi zamagetsi zam'mnyewa kuti zikhazikitse zolimba, komwe kumakhala umboni wothandiza.

Mafuta ambiri okhala ndi asidi.

Zokwera mtengo, chilichonse chomwe munthu anganene. Makhoza kukhumudwitsa m'mimba.

Ndiwosavuta kugwiritsa ntchito moyang'aniridwa ndi wopanga zakudya ndi kuwonongeka koyambirira kwamafuta a metabolism, ndikuwonjezereka pang'ono kwa cholesterol. Kuthandizidwa bwino ndi chakudya chopanda malire, kugwiritsa ntchito nsomba zochepa zam'nyanja yamafuta (komabe, Omacor idzakhala yotsika mtengo kusiyana ndi kumwa pafupipafupi kwa nsomba zamafuta abwino).

Mankhwala apamwamba kwambiri omwe ali ndi mlingo wokwanira wa mafuta a omega 3 acid, malinga ndi kafukufuku waposachedwa, kutenga omega 3 mafuta acids kwa nthawi yayitali sikulepheretsa kukula kwa matenda a mtima.

Zodula kwambiri, makamaka zogwiritsa ntchito nthawi yayitali.

Sindimagwiritsa ntchito pochita chifukwa chosowa kutsimikizira deta yake pamaluso ake.

Omacor ndi mankhwala abwino. Zatsimikiziridwa kuti zimatha kuchepetsa kufa kwa odwala omwe ali ndi contractility yochepa. Amatsika triglycerides m'mwazi, koma osati cholesterol. Mankhwalawa amagwira ntchito kwa nthawi yayitali. Ndimayamwa 1 kapu imodzi 1 pa tsiku kwa nthawi yayitali.

Pogwiritsa ntchito nthawi yayitali, kuchuluka kwa ALT, AST kunawonedwa. Mtengo ndiwokwera kwambiri, si odwala onse omwe amapezeka.

Zambiri za polyunsaturated omega 3 mafuta acids. Chiwerengero cha EPA ndi duodenum 1.2: 1 ndichabwino kwambiri. Kukonzekera koyera, kopanda zosayera. Ngati muyika mufiriji, kapisolo kamakhala kowonekera. Imagwira ntchito bwino.

Mtengo Kutsika mtengo pang'ono. Zimayambitsa nseru kwa odwala ena, koma izi ndizosowa. Nthawi zambiri wodwala amakhala ndi vuto la ndulu.

Gawirani onse. Osati kokha zaka 40. Awa ndi mafuta osasinthika osakwaniritsidwa; munthu sangathe kuwapanga. Simupeza mlingo wotere kuchokera ku nsomba.

Kukonzekera bwino kwamafuta a omega-3. Muzochita zanga, mankhwalawa amawonjezera HDL, amachepetsa pang'ono triglycerides, kuphatikiza mlingo wa cholesterol yonse umachepetsedwa motsutsana ndi maziko amankhwala osankhidwa bwino. Mankhwalawa samakhudza LDL, chifukwa chake, kuti muchepetse LDL, gulu lina la mankhwala limagwiritsidwa ntchito - statins.

Chofunikira tsiku lililonse kwa munthu ndi 1000 mg patsiku, chofunikira chofunikira ndi 300 mg patsiku. Ngati simudya pafupipafupi nsomba zamafuta (mackerel, salmon, hering), muyenera kukonzekera zowonjezera za omega-3 acid acid mu tsiku lililonse la 1000 mg kuti mupewe matenda a mtima.

Omacor sangagwiritsidwe ntchito kutsitsa cholesterol yamagazi, ngakhale nthawi zambiri imayikidwa popanda chifukwa. Itha kutsika ma triglycerides m'magazi, koma pazilingo zochepa zomwe zimakwanitsa. Adawonetsera kuthekera kwake kuchepetsa odwala mu mtima wochepa. Komabe, iwo omwe amayenera kutengedwa omacor ayenera - palibe odwala ambiri chotere.

Nthawi zambiri imakhazikitsidwa popanda chifukwa chomveka, chomwe chimachepetsa bajeti yaying'ono ya odwala ena. Ndikutsimikizira: pokhapokha ngati mulibe zifukwa zomveka zokwanira.

Ngati mukungofunika kumwa ma omega-3 mafuta achilengedwe monga gawo lofunikira la chakudya (monga mavitamini), ndiye kuti simuyenera kutenga omacor. Zowonjezera zokhala ndi omega-3 acid - omeganol, eikonol, etc. ndizokwanira.

Chenjezo ndi matenda a chiwindi.

Mankhwala apadera Omega - 1000 mg. Palibe wina aliyense yemwe ali ndi mlingo waukulu wamafuta a polyunsaturated mafuta acids - ndipo ndiwabwino! Kapisozi 1 imatengedwa kamodzi patsiku - kwa nthawi yayitali. Mankhwala okwera mtengo, koma ofunikira kutalika kwa moyo. Udindo wake waukulu ndikuchepetsa VLDL yoyipa ndikuwonjezera HDLP yopindulitsa. Ku Europe ndizovomerezeka kuyambira zaka 12, ndipo tili ndi zaka 18. Mtengo wake ndi wokwera mtengo pang'ono popeza wopanga ndi Denmark. Mankhwala athu apakhomo, mlingo ndiwotsika 2, ndipo mtengo ndi wokwera ku Russia. Ndimasankha Omacor!

Mankhwala omwe ndimakonda a omega-3 ndi mankhwala osokoneza bongo, osati othandizira pakudya. Mukumvetsa kwanga, patatha zaka 40, ziyenera kuledzera ndi aliyense yemwe alibe zotsutsana ndi kuvomereza kwake. Uku ndikupewa wabwino wamatenda amtima, kwa anthu onenepa kwambiri, nthawi zambiri mankhwalawa amachepetsa kwambiri lipid.

Muzochita zanga, miseru ndi m'mimba zodziwika zokha zomwe zimadziwika ndi mavuto, kenako ochepa odwala.

Ndimapereka mankhwala nthawi zambiri, mosiyanasiyana, kutengera BMI.

Ndemanga za Odacor za Omacor

Mankhwala "Omacor" mumsika wathu akhala mankhwala ambiri kwa odwala ambiri mdziko lathu. Kafukufuku wambiri pamunda wamtima amawonetsa kugwira bwino ntchito kwa mankhwalawa. Akatswiri athu azachipatala akugwiritsa ntchito mankhwalawa mwachangu.

Ndimagwira ntchito zolimbitsa thupi, chifukwa cha izi, mavitamini ndi michere ndizofunikira kwambiri m'zakudya zanga, ndikufuna kunena kuti mankhwalawa ali ngati, ndikofunikira kwambiri kumwa. Zotsatira zoyipa, sindinazindikire chilichonse, ngakhale mnzakeyo anali ndi mseru. Kukonzekera ndi kwabwino, ndinakhuta!

Ndikufuna kugawana nkhani yanga: nthawi inayake idabwera m'moyo wanga nditazindikira kuti kunenepa kwambiri ndi cholepheretsa kukhala ndi moyo. Zimasokoneza maubwenzi ndi ena, makamaka atsikana komanso thanzi lawo. Kenako ndidaganiza momveka bwino kuti ndiyenera kudya zakudya. Ndinayesa mulu wa chilichonse, m'njira zambiri zosiyanasiyana, zakudya zopatsa thanzi zinabwera. Adataya 10 kg ndipo adayamba kuwona kuti china chake chikuchitika ku thanzi lake. Chizungulire, kufooka, mavuto ndi kapamba, ndipo kulemera kwake kunakwera panthawi imeneyi, ndiye ndinalangizidwa omacor, ndikuganiza kuti ndizowonjezera pa zakudya zilizonse. Ndipo mukudziwa, kulemera kunayamba kuchokapo, ndipo mwachangu kuposa momwe ndimayembekezera, ngati kagayidwe kamafulumira. Sindikumvetsa momwe mankhwalawa amagwirira ntchito, koma ndikudziwa motsimikiza zomwe zimagwira! Zotsatira zake ndi: kusiya 25 kg. Ndikumva bwino. Palibe mavuto m'mimba (ndipo izi ndizofunikira kwambiri, chifukwa sizobisika kuti mankhwala ambiri amakhudza m'mimba). Ndipo pambali pake, izi ndizotengera chidziwitso chokha chogwiritsira ntchito omacor.

Kufotokozera kwapfupi

Omacor ndi mankhwala ochiritsira mawonekedwe a lipid. Kuphatikiza ndi mankhwala ena, imagwiritsidwa ntchito popewa kulowetsedwa kwa myocardial. Ngati zakudya sizikuyenda bwino ndi hypertriglyceridemia, zitha kugwiritsidwa ntchito ngati chithandizo chokhacho, komanso kuphatikiza ndi ma statins.

Omacor amagwiritsidwa ntchito kwambiri mwa odwala pambuyo poyambira myocardial infracation ngati njira yolepheretsedwera. Pokhudzana ndi odwala a mbiri iyi, adotolo amachita zinthu ziwiri zazikulu: kukonza moyo ndi kuwonjezera kuchuluka kwa moyo, kuphatikiza kupewa kumangidwa kwamtima mwadzidzidzi. Kutha kwa Omacor kuchepetsa chiopsezo chamangidwa mwadzidzidzi kwamtima kumatsimikiziridwa ndi kafukufuku wamkulu wazachipatala wokhudzana ndi odwala oposa 10,000. Chimodzi mwazofunikira pakutsimikizika kwake ndikuti sizinadzozedwe ndi wopanga, koma zidachitika ndi asayansi odziyimira okha a Italy Association of Cardiology mwa iwo okha. Omacor wakhala chida chachisanu cholimbikitsidwa ndi European Cardiology Society kuti chigwiritsidwe ntchito ngati chida chachiwiri chothandizira kupewa odwala omwe atengedwa pambuyo pake. Omacor wapadera amapanga zingapo zake. Chifukwa chake, mosiyana ndi zowonjezera zomwe zimagwiritsa ntchito kwachilengedwe zomwe sizomwe zimagwiritsa ntchito mankhwala osokoneza bongo, zimakhala ndi mafuta acids a omega-3-polyunsaturated acid acid (pano - omega-3-PUFA) osakhala triglycerides, koma ethyl esters omwe ali ndi maselo osiyanasiyananso motero Makhalidwe abwino kwambiri a pharmacokinetic ndi pharmacodynamic. Ziyenera kuwonjezera kuti kuchuluka kwa omega-3-PUFAs ku Omacor ndi okwera kwambiri: amaika 90% ya kulemera konse kwa kapisozi, ndipo mu dziwe lonse la omega-3-PUFA 84% ndiye mafuta acids - eicosapentaenoic ndi docosahexaenoic ambiri.

Kutsika kwa triglycerides motsogozedwa ndi Omacor kumachitika chifukwa chakuchepa kwa kuchuluka kwa komwe kumatchedwa "Cholesterol yoyipa" - lipoprotein yotsika komanso yotsika kwambiri. Omacor amatsutsana mwa anthu omwe ali ndi vuto la mankhwala, odwala omwe ali ndi vuto lochulukirapo la triglycerides (mtundu I hyperchylomicronemia), amayi apakati ndi amayi oyamwitsa. Nthawi yokwanira kudya ndi chakudya. Pazifukwa zodzitetezera, mankhwalawa amatengedwa 1 nthawi patsiku. Mulingo umodzi - 1 kapisozi. Kutalika kwa nthawi ya maphunzirowa kumatsimikiziridwa ndi adokotala. Ndi hypertriglyceridemia, pharmacotherapy imayamba ndi makapisozi awiri patsiku ndi mwayi woti ungachite mobwerezabwereza mlingo osakwanira achire. Mukamamwa ndi mapiritsi opatsirana piritsi, Omacor amawonjezera chiopsezo cha kuchuluka kwa magazi nthawi yayitali. Zomwezi zimachitikanso ndi monotherapy yogwiritsa ntchito Mlingo wa Omacor wapamwamba (4 makapisozi). Omacor amatha kuyambitsa hepatic transaminases.

Pankhani yakukambirana zakuyenda bwino kwa Omacor, kafukufuku wina wochitidwa mothandizidwa ndi European Congress of Cardiology ndiwokondweretsa. Zinatenga pafupifupi zaka zinayi ndikuchiritsa odwala oposa sikisi. Kafukufukuyu adawonetsa kuti Omacor amachepetsa kwambiri kuchuluka kwa kufa mwadzidzidzi komanso kuchipatala kwa odwala omwe ali ndi mtima wamtima. Pogwiritsa ntchito Omacor pafupipafupi, kufa kwatsika ndi 9,2%, ndi kuchipatala - ndi 8.7%. Malingana ndi izi, mankhwalawa amapitilira chithandizo chazomwe amagwiritsa ntchito angiotensin-converting enhibme inhibitors, beta-blockers, diuretics, etc.

Pharmacology

Hypolipidemic mankhwala. Mafuta a polyunsaturated acids a kalasi la omega-3 - eicosapentaenoic acid (EPA) ndi docosahexaenoic acid (DHA) - ndi osagwiritsidwa ntchito (ofunikira) amafuta acid (NEFAs).

Omacor amachepetsa ndende ya triglycerides chifukwa cha kuchepa kwa ndende ya VLDL, kuwonjezera apo, imakhudza kuthamanga kwa magazi ndi hemostasis, ndikuchepetsa kapangidwe ka thromboxane A₂ ndi kuchuluka kwakuchulukitsa magazi nthawi. Palibe phindu lililonse pazinthu zina zovuta

Omacor amachedwetsa kapangidwe ka triglycerides mu chiwindi (poletsa mphamvu ya EPA ndi DHA). Kutsika kwa ndende ya triglyceride kumathandizidwa ndi kuwonjezeka kwa peroxisome ya beta oxidation yamafuta acids (kuchepa kwa kuchuluka kwamafuta acids omwe amapezeka pakuphatikizidwa kwa triglycerides). Kuletsa kaphatikizidwe kameneka kumachepetsa VPLL. Omacor amadzutsa cholesterol ya LDL mwa odwala ena omwe ali ndi hypertriglyceridemia. Kuwonjezeka kwa ndende ya HDL ndikochepa komanso kotsika kwambiri kuposa mutatha kutenga ma fibrate.

Kutalika kwa zotsatira za lipid-kuchepetsa mukamagwiritsa ntchito mankhwala Omacor kwa chaka chopitilira sikunaphunzire. Kupanda kutero, palibe umboni wotsimikiza kuti kutsitsa triglycerides kumachepetsa chiopsezo chokhala ndi CHD.

Zotsatira zamankhwala zamaphunziro a Omacor pa mlingo wa 1 g / tsiku kwa zaka 3.5 zinawonetsa kuchepa kwakukulu kwa chizindikiro, kuphatikiza kufa kwathunthu kuzomwe zimayambitsa, komanso kupha infrction komanso kopanda magazi myocardial.

Pharmacokinetics

Pakati kapena pambuyo kunyamula m'mimba yaying'ono ya omega-3 mafuta acid, pali njira zitatu zazikulu za kagayidwe kake:

• mafuta acids amaperekedwa koyamba pachiwindi, komwe amaphatikizidwa m'magulu osiyanasiyana a lipoprotein ndipo amatumizidwa m'masitolo ophatikizira a lipid,
• phospholipids a membrane wamaselo amaloledwa ndi lipoprotein phospholipids, pambuyo pake mafuta acids amatha kukhala ngati patsogolo pa ma eicosanoids osiyanasiyana,
• mafuta ochulukirapo amakhatidwa kuti akwaniritse zofunika zamagetsi.

Kuphatikizika kwa omega-3 mafuta acids (EPA ndi DHA) mu phospholipids wa plasma amafanana ndi kuchuluka kwa mafuta awa omwe amaphatikizidwa ndi cell membrane.

Kutulutsa Fomu

Makapisozi otsekemera a gelatin, owoneka bwino, saizi No. 20, zomwe zili m'mabotolo ndi madzi owala achikasu amadzimadzi.

Othandizira: α-tocopherol - 4 mg.

Mapangidwe a chipolopolo cha kapisozi: gelatin - 293 mg, glycerol - 135 mg, madzi oyeretsedwa - q.s.

28 ma PC. - mabotolo a polyethylene (1) - makatoni.
Ma PC 100 - mabotolo a polyethylene (1) - makatoni.

Mankhwalawa amatengedwa pakamwa pakudya kuti asayambitse zovuta zoyipa zam'mimba.

Ndi hypertriglyceridemia, muyeso woyamba wa Omacor ndi 2 kap./day. Palibe achire zotsatira, n`zotheka kuwonjezera mlingo kuti pazipita tsiku lililonse mlingo 4 zisoti. Kutalika kwa mankhwalawa komanso maphunziro obwereza amakhazikitsidwa ndikuvomereza kwa dokotala.

Popewa yachiwiri ya kulowetsedwa kwa myocardial, tikulimbikitsidwa kutenga 1 makapu / tsiku. Kutalika kwa mankhwalawa komanso maphunziro obwereza amakhazikitsidwa ndikuvomereza kwa dokotala.

Malangizo ogwiritsira ntchito Omacor, mlingo

Mankhwalawa amatengedwa pakumwa pakudya (kuti muchepetse chiopsezo chokhudzana ndimatumbo).

Mlingo wovomerezeka ndi malangizo a Omacor:

• Kupewera kwachiwiri kwa kulowerera kwa myocardial - 1 kapisozi 1 nthawi patsiku.
• Hypertriglyceridemia: mlingo woyamba ndi makapisozi awiri patsiku (pakalibe njira zochiritsira kuchokera ku chithandizo, ndizotheka kuwonjezera mlingo wa makapiritsi 4 patsiku).

Kutalika kwa maphunzirowa kumachitika ndi dokotala payekhapayekha.

Malangizo apadera

Odwala omwe amamwa mankhwala a anticoagulant ayenera kutumikiridwa mlingo wa tsiku ndi tsiku wa mapiritsi oposa 4 mosamala.

Anthu omwe ali ndi vuto la chiwindi ndi chiwopsezo chakutuluka magazi ayenera kutenga Omacor mosamala kwambiri.

Zotsatira zoyipa

Malangizowa akuwachenjeza za mwayi wokhala ndi zotsatirazi zomwe zingapatsidwe mankhwala Omacor:

• Kuchokera pamimba yogaya chakudya: Reflux kapena burping ndi fungo kapena kukoma kwa nsomba, nseru, kusanza, kugona mosatekeseka, kutsekula m'mimba kapena kudzimbidwa.
• Kuchokera pakhungu, kawirikawiri: eczema, ziphuphu.
• Pa mbali ya kupuma dongosolo: kuyanika kwa mucosa wammphuno.
• Thupi lawo siligwirizana ndi zigawo zikuluzikulu.
• Zizindikiro zasayansi: kuchuluka kwakukulu kwa ntchito za "chiwindi" transaminases.

Contraindication

Amatsutsana kuti apereke Omacor pazochitika zotsatirazi:

• Kusalolera payekhapayekha pazigawo za mankhwala,
• Zofika zaka 18 (palibe zambiri pazokhudza ana)
• Mimba komanso kuyamwa
• Hyperchilomicronemia mtundu I.

Mosamala, mankhwalawa amayenera kulembedwa kwa odwala okalamba (azaka zopitilira 70), omwe ali ndi vuto la chiwindi, kugwiritsa ntchito pamodzi ndi anticoagulants pamlomo, mafupa, hemorrhagic diathesis, kuvulala kwambiri, opareshoni (chifukwa chakuwonjezeka kwa kuchuluka kwa magazi nthawi).

Zomwe zimachitika ndi sekondaleos hypertriglyceridemia ndizochepa (makamaka ndi matenda osokoneza bongo a shuga).

Bongo

Ngati bongo wa mankhwala osokoneza bongo, zotsatira zoyipa zimachitika. Mankhwalawa ndi chizindikiro.

Analogs Omacor, mtengo pama pharmacies

Ngati ndi kotheka, mutha kubwezera Omacor ndi analogue mu achire - awa ndi mankhwala:

Mechi ya ATX:

Mukamasankha analogi, ndikofunikira kumvetsetsa kuti malangizo ogwiritsira ntchito Omacor, mtengo ndi zowunikira sizikugwira ntchito ndi mankhwalawa ofanana. Ndikofunikira kupeza upangiri wa dokotala komanso kuti usasinthe popanda mankhwala.

Mtengo m'mafakitale aku Russia: Omacor 1000mg 28 makapisozi - kuyambira 1887 mpaka 2143 rubles, malinga ndi 731 pharmacies.

Pewani kufikira ana pa kutentha osapitirira + 25 ° C. Osamawuma. Moyo wa alumali ndi zaka zitatu.

Zoyenera kufalitsa kuchokera ku mafakitala zimalembedwa ndi mankhwala.

Ndemanga 6 za "Omacor"

Ndiwosavuta kugwiritsa ntchito moyang'aniridwa ndi wopanga zakudya ndi kuwonongeka koyambirira kwamafuta a metabolism, ndikuwonjezereka pang'ono kwa cholesterol. Kuthandizidwa bwino ndi chakudya chopanda malire, kugwiritsa ntchito nsomba zochepa zam'madzi zam'madzi (komabe Omacor imakhala yotsika mtengo kuposa kumwa pafupipafupi kwa mafuta abwino).

Omacor ndi kukonzekereratu kwamafuta a nsomba ndipo, mwina, amathanso kusintha m'malo mwake ndi omaliza. Koma ngati tilingalira za mankhwala othandizira, ndiye kuti Omacor wokhala ndi Omega-3 pa kapisozi iliyonse 1000 mg, wopindulitsa kwambiri ndi voliyumu imodzi patsiku motsutsana ndi makapisozi 3-18 a mafuta a nsomba komanso pamtengo ngati mutatenga mafuta ochokera kumayiko ena otchuka (mwachitsanzo ndi iHerb).

Madokotala alemba kuti mankhwalawa Omega 3, monganso 3-6-9, sanayesedwe mokwanira kuti atsimikizire kuti amagwira ntchito bwino. Zokhudza Omacor zokha.

Pambuyo pa chithandizo chamankhwala, ndimayenera kutsatira mtundu wina, adotolo adandiuza kuti ndisale. Ndinkamwa makapu awiri, mutu wanga unayamba kutuluka. Kudutsa 1 Chilichonse chadutsa. Zimakhudza kwambiri magazi mthupi, kuletsa magazi, mkaka amamwa pambuyo podzisokoneza.

Ndimapanga "Omega-3" ku Germany, ndizotsika mtengo kwambiri, koma zotsatira zake ndizofanana. Ndipo kapangidwe kofanana.

Anandiika mankhwala operewera. Ndili ndi mavuto am'mimba, nseru, gastritis, etc. Kodi ndingomwera mafuta am'madzi?

Analogs ndi mitengo ya mankhwala Losacor

mapiritsi okhala ndi filimu

mapiritsi okhala ndi filimu

mapiritsi okutira

mapiritsi okhala ndi filimu

mapiritsi okhala ndi filimu

mapiritsi okhala ndi filimu

mapiritsi okutira

mapiritsi okhala ndi filimu

mapiritsi okhala ndi filimu

Mavoti onse: madokotala 45.

Zambiri za omwe adayankha mwapadera:

Mapiritsi a Omacor

Omacor ndi m'gulu la mankhwala antisulinotic zochokera ku eicosapentaenoic ndi docosahexaenoic acid, omwe ndi omega-3 acid. Amayang'anira kuchuluka kwa glycerides ndi lipids, ndikuthandizira kupewa chiopsezo cha myocardial infarction ndi matenda ena ogwirizana ndi kuchuluka kwa triglycerides. Omacor ali ndi mawonekedwe ake ogwiritsira ntchito.

The kapangidwe ka mankhwala Omacor

Mankhwala amapezeka mu mawonekedwe a makapisozi a gelatin oonekera omwe amakhala ndi madzi achikasu amadzimadzi. Zadzaza m'mabotolo apulasitiki a zidutswa 28 ndi 100. Zomwe zili mu kapisozi ndi chipolopolo zimaperekedwa pagome:

Ethyl Omega-3-Acids

Docosahexaenoic Acid Ethyl Ester

Eicosapentaenoic Acid Ethyl Ester

Othandizira, kuphatikizapo α-tocopherol

Zigawo za zigamba za kapisozi: glycerol, gelatin, madzi oyeretsedwa

Malangizo ogwiritsira ntchito Omacor

Mankhwalawa adapangira kuti azigwiritsidwa ntchito pakamwa ndi chakudya. Ngati chizindikirocho chikugwiritsidwa ntchito ndikupewa sekondale ina, ndiye kuti mlingo umodzi ndi kapisozi patsiku. Zochizira hypertriglyceridemia, mlingo woyambirira ndi makapisozi awiri / tsiku. Pakadalibe chithandizo chamatenda kwambiri, mankhwalawa akhoza kuchuluka mpaka makapu anayi / tsiku. Dokotala amafotokoza kutalika kwa chithandizo payekha. Odwala ndi mkhutu aimpso ntchito, mlingo sasintha.

Pa nthawi yoyembekezera

Mpaka pano, palibe cholinga komanso chidziwitso chovomerezeka pamakhalidwe omwe amamwa mankhwalawa panthawi yapakati. Pachifukwa ichi, kugwiritsa ntchito mankhwalawa ndizotheka mosamala, pokhapokha ngati pali kumvetsetsa kuti kuthekera kopindulitsa kwa amayi kudzakhala kwakukulu kuposa chiwopsezo cha mwana wosabadwa. Pa mkaka wa m`mawere, mankhwala saloledwa.

Muubwana

Palibe maphunziro a zamankhwala okhudzana ndi mankhwalawa kwa ana ndi achinyamata ochepera zaka 18. Ndikosatheka kudalira molondola komanso motsimikiza za zotsatirapo zake za kumwa mankhwalawo malinga ndi kuthekera ndi chitetezo chokwanira. Pachifukwa ichi, kusankha Omacor onse mu monotherapy komanso kuphatikiza mankhwala ena pamagulu awa ayenera kuonedwa ngati osayenera.

Kukwanira kwa Omacor ndi Mowa

Mowa sayenera kumwedwa panthawi ya mankhwala a Omacor. Zinthu zonse ziwiri zimakonzedwa ndi chiwindi, ndikuwonjezera katundu pa chiwalo. Izi zingayambitse kuledzera kwa thupi, kukulitsa zovuta komanso kuwonongeka kwa zotsatira za mankhwalawo. Pambuyo pa kutha kwa mankhwalawa ndi mankhwalawa, sikulimbikitsidwa kumwa zakumwa zoledzeretsa zamankhwala osokoneza bongo kwa masiku angapo.

Kuyanjana kwa mankhwala osokoneza bongo

Kuphatikizika kwakamodzi kwa Omacor ndi ma fibrate, ma anticoagulants amkamwa ndi mankhwala ena omwe amakhudza hemostasis kumawonjezera chiopsezo chowonjezeka nthawi yakukha magazi. Warfarin (anticoagulant yosagwiritsidwa ntchito) mosakanikirana ndi mankhwala samayambitsa zovuta za hemorrhagic, koma, pankhaniyi, kuyang'anira kuchuluka kwa magazi a matenda apakati padziko lonse lapansi ndikofunikira. Mankhwala amachepetsa mphamvu ya insulin.

Bongo

Madokotala samatchulapo milandu yowopsa ya mankhwala osokoneza bongo. Ngati mulingo woyenera wonjezedwa, kuchulukitsa kwa zotsatira zoyipa ndikotheka. Zikaonekera, muyenera kusiya kumwa mankhwalawo ndi kupita kwa dokotala. Odwala omwe akuyembekezeredwa bongo amawonetsedwa: a chithandizo cha mankhwala, chifuwa cha m'mimba, kutenga ma sorbets.

Migwirizano yogulitsa ndikusunga

Mankhwala atha kugulidwa ndi mankhwala. Iyenera kusungidwa kuti isafikire ana pamatenthe mpaka 25 digiri. Moyo wa alumali suyenera kupitilira zaka zitatu.

Omacor olowa m'malo mwake amaphatikizanso mankhwala omwe ali ndi chinthu chimodzi chomwecho pakapangidwe kena kake, koma amawonetsa zotsatira zofananira ndi thupi la munthu. Zofananira zamankhwala:

• Vitrum Cardio Omega-3 ndi analogue mwachindunji ndi chophatikizira chomwechi,
• Angionorm ndi kukonzekera kwazitsamba pochiza matenda omwe amatsatiridwa ndi vuto la mtima,
• Mafuta a nsomba - muli ma omega-3 ovuta (atha kupezeka kuchokera ku eel, nsomba).