Fervex ya akulu popanda shuga - malangizo, ntchito, kuchuluka, kumwa, mavuto

Fervex ya akulu popanda shuga

Fervex ya akulu popanda shuga (Fervex ya achikulire a shuga yaulere)

Makhalidwe oyambira a physico: ufa wopepuka wa granular,

Kupanga. 1 sachet imaphatikizapo pheniramine amuna 25 mg, paracetamol 500 mg, ascorbic acid 200 mg,

zigawo zina: mannitol, anhydrous citric acid, povidone, trimagnium dicitrate anhydrous, aspartame (shuga wogwirizira), kununkhira kwachilengedwe kwa Antillean.

Njira yotulutsira mankhwala.

Ufa wa yankho lagwiritsira ntchito mkati.

Gulu la Pharmacotherapeutic.

Ma analgesics ndi antipyretics. Nambala ya PBX N02B E51.

Zochita zamankhwala.

Chikhazikitso cha mankhwalawa Fervex ndi kuphatikiza kwa mankhwala othandiza komanso otetezeka omwe amagwira ntchito pazolumikizira zazikulu za pathogene. Paracetamol ili ndi antipyretic ndi analgesic kwenikweni, ascorbic acid - imakwaniritsa zofuna za thupi zofunikira za vitamini C, zomwe zimachulukana ndi chimfine, pheniramine maleate - blocker of H1-histamine receptors, imapereka zotsatira zoyipa, zomwe zimawonetsedwa ndi kuchepa kwa mphamvu ya mucous membranes ya kupumira kwamkati , mphuno zam'mimba zimachepa, kusisima komanso kusuntha kwamtuwa kumatha. Wokonzekera ngati njira yofunda yokhala ndi kukoma ndi fungo labwino, mankhwalawa amachepetsa mavuto a kuledzera.

Pharmacokinetics

Paracetamol pambuyo pakamwa makonzedwe ake imakhala yofulumira ndipo imatsala pang'ono kulowa m'mimbamo. Pazitali zambiri za paracetamol mu plasma zimatheka patatha mphindi 30-60 pambuyo pa makonzedwe. Paracetamol imapangidwa makamaka mu chiwindi kuti ipange mankhwala ndi glucuronic acid ndi sulfates. Pochulukirapo (zosakwana 4%) zimapangidwa ndi oxidation ndikupanga cysteine ndi mercaptopuric acid (ndikuchita nawo cytochrome P450).

Amayikamo mkodzo, makamaka mawonekedwe a metabolites. Pafupifupi 5% ya mankhwalawa amatengedwa osasinthika.

Kuchotsa theka moyo kumapangitsa 2-2, 5 maola. Kagayidwe ka paracetamol mwa odwala omwe ali ndi vuto la chiwindi sikusintha.

Ascorbic acid (Vitamini C) amatengeka mosavuta m'mimba. Pambuyo pa mayamwidwe, imazungulira m'madzi a m'magazi ndipo imazungulira mu gland ya endocrine. Imapezeka pamtunda waukulu wa ubongo komanso ubongo wa adrenal gland. Kuchuluka kwa ascorbic acid mu leukocytes ndi mapulateleti ndi apamwamba kuposa plasma. Ascorbic acid imapangidwa pang'ono ndi oxalic acid kapena ma metabolite ena osungunuka am'madzi, ndikufotokozedwa pang'ono ndi impso mwanjira yosasintha. The catabolism of ascorbic acid ndi 2, 2-4, 1% ya thupi lathunthu, lomwe limatsimikiziridwa kuti 1500 mg. Amakhulupirira kuti kupezeka kwa thupi kumeneku ndikokwanira 1-1, miyezi 5 chifukwa chosowa vitamini C mu chakudya. Kuchiritsa kwamchiwachi kumayamba pakatha kuchuluka kwa malo ogulitsa ndi oposa 1500 mg. Odwala omwe ali ndi malo ochepetsa, mavitamini C sangawonekere mkodzo ngakhale atapatsidwa mankhwala ambiri mkati kapena mwaubwino. Hafu ya moyo wa ascorbic acid imachokera 12, 8 mpaka 29, masiku 5.

Pheniramine maleate amatengeka bwino kuchokera ku alimentary ngalande ndipo amalowa mosavuta minofu. Hafu ya moyo kuchokera ku plasma ndi 1-1, maola 5, imachotsedwa m'thupi makamaka ndi impso.

Zizindikiro zogwiritsidwa ntchito.

Zizindikiro zochizira chimfine, chifuwa chachikulu, chimfine, rhinopharyngitis, omwe amawonetsedwa ndi matenda am'mimba, kupweteka mutu, mphuno, kuzizira ndi kupindika.

Njira yogwiritsira ntchito ndi mlingo.

Mkati, kwa akulu ndi ana opitirira zaka 15, mankhwalawa amayikidwa pakiti limodzi katatu patsiku. Zomwe zili mchikwatacho zimasungunuka kapu yamadzi ozizira kapena ofunda. Odwala omwe ali ndi vuto la chimfine amayenera kutenga njira yofunda. Mlingo woyamba uyenera kuchitika mwachangu atangoyamba kumene kwa matenda. Njira yothetsera vutoli imatengedwa mukatha kukonzekera. The pakati pakati Mlingo ayenera kukhala osachepera 4 maola.

Njira ya mankhwala palibe masiku atatu.

Zotsatira zoyipa.

Kugona, pakamwa pouma, kusokonezeka kwa malo okhala, kusungirako kwamikodzo, kudzimbidwa, kusasamala ndi kukumbukira, kusasamala, makamaka okalamba, ndizotheka.

Kawirikawiri, thupi siligwirizana (zotupa, urticaria).

Osowa kwambiri - thrombocytopenia, kuchepa magazi, agranulocytosis, aimpso colic.

Zolepheretsa ndi zotsutsana pakugwiritsa ntchito mankhwalawa.

Hypersensitivity pamagawo a mankhwala,

chiwindi ndi impso kwambiri.

chizolowezi cha thrombosis,

Prostate adenoma,

osakwana zaka 15

phenylketonuria (popeza mankhwalawa akuphatikizapo aspartame),

Kupitilira muyeso wovomerezeka wa mankhwala (bongo).

Pankhani ya mankhwala osokoneza bongo, kuwopsa kwa mankhwalawa kungayambike chifukwa cha: pheniramine ndi paracetamol, yomwe imawonetsedwa ndi kukomoka, chikumbumtima chovulala, chikomokere. Amadziwika kuti kumwa paracetamol muyezo woposa 4 g patsiku (kwa akuluakulu) kumatha kuwononga chiwindi ndikupangitsa hepatonecrosis.

Zizindikiro za kuledzera (mseru, kusanza, kudwala, kupweteka kwam'mimba, thukuta kwambiri) zimachitika kawirikawiri m'maola 24.

Chithandizo: hospitalization, chapamimba, N-asethylcysteine, womwe umathandizidwa pakamwa, methionine, symptomatic mankhwala, umagwiritsidwa ntchito kwa maola 10 oyambirira monga mankhwala a paracetamol.

Mawonekedwe akugwiritsidwa ntchito.

Gwiritsani ntchito mosamala odwala omwe ali ndi matenda ashuga.

Mowa umapangitsanso kusintha kwa pheniramine maleate, hepatotoxicity ya paracetamol.

Mankhwalawa amatha kuyambitsa kugona, zomwe zimapangitsa kukhala kosavomerezeka kuyendetsa magalimoto ndikugwira ntchito ndi zida.

Palibe zambiri pazovuta za mankhwalawa pamimba ndi mkaka wa m'mawere, komabe, mankhwalawa ayenera kuyikidwa nthawi imeneyi mosamala kwambiri, poganizira kuopsa / kufananiza.

Ascorbic acid imatha kusintha zotsatira za mayeso a labotale (glucose, magazi bilirubin, transaminase).

Popewa mankhwala osokoneza bongo, kukonzekera konse komwe kumakhala ndi paracetamol kuyenera kufotokozedwa ndikusiyidwa.

Kwa odwala mkhutu aimpso ntchito ndi creatinine chilolezo

Fomu ya Mlingo:

Chikwama chilichonse chimakhala ndi:
ntchito: paracetamol - 0,000 g, ascorbic acid - 0,200 g, amuna a pheniramine - 0,2525 g.
obwera: mannitol 3.515 g, citric acid 0,050 g, povidone KZO 0,10 g, magnesium citrate 0,400 g, aspartame 0,050 g, kununkhira kwa limu-rum-0,200 g.

The ufa ndi wopepuka beige. Mabulangete amaloledwa.

Mankhwala

Mankhwala
Fervex ® ndi njira yophatikizira yomwe ili ndi paracetamol, pheniramine ndi ascorbic acid. Paracetamol ndi analgesic yopanda narcotic yomwe imalepheretsa cycloo oxygenase, makamaka mkati mwa mantha am'mimba, imagwira malo opweteka komanso othandizira, ndipo imakhala ndi analgesic komanso antipyretic.
Pheniramine - H blocker₁-histamine zolandilira, amachepetsa rhinorrhea ndi lacrimation, amachotsa zotupa, zotupa ndi hyperemia ya mucous nembanemba wa mucous, nasopharynx ndi paranasal sinuses. Ascorbic acid imakhudzidwa ndi kayendedwe ka njira za redox, kagayidwe kazakudya, kuphatikizika kwa magazi, kusinthika kwa minofu, kaphatikizidwe ka mahomoni a steroid, kumachepetsa kuvulala kwamitsempha, kumachepetsa kufunika kwa mavitamini B₁, Mu₂, A, E, folic acid, pantothenic acid. Imawongolera kulolerana kwa paracetamol ndikuwonjezera mphamvu yake (yogwirizanitsidwa ndi T½).

Pharmacokinetics
Paracetamol
Pambuyo pakukonzekera pakamwa, imatengedwa mwachangu kuchokera m'mimba. Pazitali kwambiri ya mankhwalawa m'madzi a m'magazi amafikira mphindi 10-60 pambuyo pa kuperekedwa. Imagawidwa mwachangu m'thupi lonse, imalowa mu zotchinga magazi. Kulumikizana ndi mapuloteni a plasma ndikosathandiza ndipo kulibe phindu, koma kumawonjezera ndi kuchuluka.
Kutupa kwa metabolism kumachitika m'chiwindi, 80% ya mlingo womwe umatengedwa ndi gawo la glucuronic acid ndi sulfates kuti apange metabolites yogwira, 17% imayatsidwa hydroxylation ndikupanga metabolites 8 yogwira, yomwe imalumikizana ndi glutathione kupanga metabolites kale. Imodzi mwa ma hydroxylated metabolic intermediates amawonetsa hepatotoxic. Metabolite iyi imasinthidwa ndi kulumikizana ndi glutathione, komabe, imatha kudziunjikira ndipo vuto la paracetamol (150 mg ya paracetamol / kg kapena 10 g ya paracetamol pakamwa) imayambitsa hepatocyte necrosis. Amathandizidwa ndi impso mu mawonekedwe a metabolites, makamaka mawonekedwe a conjugates. Mwanjira yosasinthika, ochepera 5% ya mankhwalawa atengedwa. Kutha kwa theka-moyo kumapangika kuyambira 1 mpaka 3 maola.
Feniramine:
Amayamwa bwino m'mimba. Hafu ya moyo kuchokera m'madzi a m'magazi imachokera ku ola limodzi ndi theka. Imapukutidwa makamaka kudzera mu impso.
Ascorbic acid:
Amayamwa bwino m'mimba. Nthawi yoti apange kuchuluka kwa achire kwambiri (TCmax) pambuyo pakukonzekera kwamlomo ndi - maola 4. Amapukusidwa makamaka m'chiwindi. Imafufutidwa ndi impso, m'matumbo, ndi thukuta, losasinthika komanso mawonekedwe a metabolites.

* Makulidwe ophatikizika: maltodextrin, chingamu, α-pinene, ß-pinene, limonene, γ-terpinene, chibwano, mafupa, cy-terpineol, geranial, dextrose, silicon dioxide Е551, butylhydroxyanisole.

Zizindikiro zogwiritsidwa ntchito

Amagwiritsidwa ntchito pa matenda am'mapapo am'mimba, kupuma kwamatenda oyamba, rhinopharyngitis kuti muchepetse zizindikiro zotsatirazi:

matenda a m'mimba,
mutu
malungo
lacure
kusisita.

Contraindication

Hypersensitivity kwa paracetamol, ascorbic acid, pheniramine kapena gawo lina lililonse la mankhwala.
Zilonda zam'mimba komanso zam'minyewa zam'mimba.
Kulephera kwa chiwindi.
Angle -otseka glaucoma.
Kusungika kwamkodzo komwe kumayenderana ndi matenda a prostate komanso matenda amkodzo.
Matenda oopsa a portal.
Mowa
Phenylketonuria.
Zaka za ana (mpaka zaka 15).
Mimba ndi mkaka wa m`mawere (chitetezo sichinaphunzire).

Ndi chisamaliro

Kulephera kwa renal, hyperbilirubinemia wobadwa nawo (Gilbert, Dubin-Johnson ndi Rotor syndromes), hepatitis, uchidakwa wa hepatitis, ukalamba.

Gwiritsani ntchito pa nthawi yoyembekezera komanso nthawi yoyamwitsa

Kafukufuku wokwanira komanso wowongolera bwino wa mankhwala Fervex ® mwa amayi apakati sanachitike, motero kugwiritsa ntchito mankhwalawa m'gulu la odwala sikulimbikitsidwa.

Sizikudziwika ngati zinthu zofunikira za mankhwalazo zimadutsa mkaka wa m'mawere. Mankhwala sayenera kugwiritsidwa ntchito pa mkaka wa mkaka.

Mlingo ndi makonzedwe

Mkati - 1 sachet katatu patsiku. Musanagwiritse ntchito, zomwe zili m'thumba ziyenera kusungunuka mu kapu (200 ml) yamadzi ofunda. Kutalika kwakukulu kwa chithandizo ndi masiku 5. Mlingo wapamwamba wa tsiku ndi tsiku wa paracetamol ndi 4 g (mapaketi 8 a mankhwala a Fervex ®) omwe ali ndi thupi loposa 50 kg. The pakati pakati Mlingo wa mankhwala ayenera osachepera 4 maola.
Odwala omwe ali ndi vuto la impso (creatinine chilolezo ®. Kuphatikiza apo, ethanol, akamagwiritsa ntchito pheniramine, amathandizira kukulitsa pancreatitis ya pachimake.
Pheniramin monga gawo lokonzekera Fervex ® imawonjezera mphamvu ya zomwe zimapangidwira: morphine derivatives, barbiturates, benzodiazepines and tranquilizer, antipsychotic (meprobamate, phenogiazine zotumphukira), antidepressants (amitriptyline, mirtazapine, mianserinent antihtog, antihyper₁-blockers, baclofen, pomwe sizingochulukitsa mphamvu yogwira ntchito, komanso akuwonjezera ngozi ya zotsatira zoyipa za mayikidwe (kwamikodzo posungira, mkamwa wowuma, kudzimbidwa)
Ndikofunikira kulingalira kuthekera kokulitsa zotsatira zapakati pa atropine ngati mugwiritsidwa ntchito limodzi ndi zinthu zina ndi anticholinergic katundu (antihistamines ena, imipramine gulu antidepressants, phenothiazine antipsychotic, m-anticholinergic mankhwala, mankhwala a atropine-antispasmodic, disopyramide).
Mukamagwiritsa ntchito mankhwalawa, limodzi ndi microsomal oxidation inducers: barbiturates, tridclic antidepressants, anticonvulsants (phenytoin), flumecinol, phenylbutazone, rifampicin ndi ethanol, chiopsezo cha hepatotoxicity chikuwonjezeka (chifukwa cha gawo la paracetamol).
Glucocorticosteroids omwe amagwiritsidwa ntchito munthawi yomweyo amawonjezera mwayi wokhala ndi glaucoma.
Kulandiridwa limodzi ndi salicylates kumawonjezera chiopsezo cha nephrotoxicity.
Pogwiritsa ntchito munthawi yomweyo ndi chloramphenicol (chloramphenicol), kuopsa kwa zinthu zomalizirazi kumawonjezeka.
Paracetamol yomwe ili ndi mankhwalawa imapititsa patsogolo zotsatira za anticoagulants osagwirizana ndikuchepetsa mphamvu ya uricosuric mankhwala.

Malangizo apadera

Mankhwalawa alibe shuga ndipo angagwiritsidwe ntchito ndi odwala omwe ali ndi matenda osokoneza bongo.
Fervex ® sayenera kugwiritsidwa ntchito nthawi yomweyo ndi mankhwala ena okhala ndi paracetamol. Popewa kuwononga chiwopsezo cha chiwindi, paracetamol sayenera kukhala limodzi ndi zakumwa zoledzeretsa, komanso zimayenera kutengedwa ndi anthu omwe amakonda kumwa mowa kwambiri.
Chiwopsezo chotenga kuwonongeka kwa chiwindi chimawonjezeka kwa odwala omwe ali ndi chiwindi cha mowa.
Mukapitirira Mlingo woyenera ndi kugwiritsa ntchito nthawi yayitali, kudalira kwa mankhwalawa kumawonekera.
Pofuna kupewa mankhwala osokoneza bongo a paracetamol, onetsetsani kuti mankhwalawa tsiku lililonse la paracetamol omwe ali m'magulu onse a mankhwala omwe wodwala sanadutse 4 g.

Kukopa pa luso loyendetsa magalimoto ndi zida

Popeza kuti mungayambitse mavuto osafunikira monga kugona ndi chizungulire, ndikulimbikitsidwa kuti musayendetse magalimoto pazomwe mukumwa mankhwala.

Wopanga

Wopanga, packer (ma CD oyambira), packer (sekondale / tertiary), kupereka mawonekedwe abwino
UPSASAS, France
979 Avenue de Pyrenees, 47520 Le Passage, France UPSASAS, France
979 avenue des Pyrenees, 47520 Le Passage, France

Zodandaula za ogula ziyenera kutumizidwa kwa:
Bristol-Myers squibb LLC, Russia 105064, Moscow, ul. Zemlyanoy Val, 9

Bungwe lovomerezeka lomwe dzina lake limalembetsedwa
UPSASAS, France
3, ryu Joseph Monnier, 92500 Rueil-Malmaison, France UPSASAS, France
3, rue Joseph Monier, 92500 Rueil Malmaison, France

The zikuchokera mankhwala

ntchito: pheniramine maleate, paracetamol, ascorbic acid (vitamini C)

1 sachet ili ndi pheniramine amuna 25 mg, paracetamol 500 mg, ascorbic acid (vitamini C) 200 mg

zokopa: mannitol (E 421), citric acid, povidone, trimagnium dicitrate anhydrous, aspartame (E 951), kununkhira kwa antillean.

Gulu la mankhwala

Ma analgesics ndi antipyretics. Nambala ya PBX N02B E51.

Zotsatira zamatsenga chifukwa cha zigawo za mankhwala:

Pheniramine Maleate - H blocker ₁ -histamine receptors, imapereka mtima wofooka, wowonekera mwa kuchepa kwa kuyamwa kwa mucous membrane ya kupuma kwam'mimba thirakiti (kupuma kwammphuno kumakhala bwino, mphuno, kutsekeka ndi kuchepa kwamadzimadzi)
paracetamol ali ndi antipyretic ndi analgesic kwenikweni,
ascorbic acid imakwaniritsa kufunikira kwa thupi kwa vitamini C, kumakula ndi chimfine.

Paracetamol Pambuyo pakukonzekera pakamwa, imathamanga ndipo imatsala pang'ono kulowa m'mimba. Pazitali kwambiri paracetamol mu madzi am'magazi amafikira mphindi 30-60 pambuyo pa kuperekedwa. Paracetamol imapangidwa m'chiwindi kuti ipange mankhwala ndi glucuronic acid ndi sulfates.

Amayikamo mkodzo, makamaka mawonekedwe a metabolites. 90% ya mankhwalawa amatengedwa ndi impso mkati mwa maola 24, makamaka mu mawonekedwe a conjugates ndi glucuronic acid (60-80%), sulfate conjugates (20-30%).

Mwanjira yosasinthika, pafupifupi 5% ya mankhwalawa amatengedwa. Kuchotsa theka-moyo pafupifupi 2:00.

Feniramine maleate odzipereka bwino m'mimba. Imapukutidwa makamaka kudzera mu impso.

Ascorbic acid odzipereka bwino m'mimba. Amapakidwa makamaka ndi mkodzo.

Zizindikiro zochizira chimfine, chifuwa chachikulu, chimfine, rhinopharyngitis, owonetsedwa ndi malungo, kupweteka mutu, mphuno, kutsinira ndi kupindika.

Njira zoyenera zotetezera

Ngati thupi lanu latentha kwambiri kapena kutentha kwa nthawi yayitali, komwe kumapitirirabe masiku 5 motsutsana ndi kugwiritsa ntchito mankhwalawa kapena ngati zizindikiro zakusonyezaku zikuwoneka, muyenera kufunsa dokotala kuti muwone kuthekera kwa kugwiritsidwanso ntchito kwa mankhwalawa.

Gwiritsani ntchito mosamala odwala omwe ali ndi matenda ashuga.

Mowa umapangitsanso kusintha kwa pheniramine maleate, hepatotoxicity ya paracetamol.

Ascorbic acid imatha kusintha zotsatira za mayeso a labotale (glucose, magazi bilirubin, transaminase).

Kuopsa kodzidalira kwambiri m'maganizo kumawonekera mukamadutsa mulingo woyenera komanso mukamalandira chithandizo kwa nthawi yayitali.

Popewa mankhwala osokoneza bongo, kukonzekera konse kokhala ndi paracetamol kuyenera kuwunikidwa ndikuchotsedwa.

Kwa akulu omwe ali ndi thupi loposa 50 makilogalamu, kuchuluka kwa paracetamol sikuyenera kupitirira 4 g patsiku.

Kugwiritsa ntchito zakumwa zoledzeretsa kapena kugwiritsa ntchito mankhwala osokoneza bongo (makamaka barbiturates) kumawonjezera mphamvu yogwira ya pheniramine maleate, chifukwa chake, zinthu izi ziyenera kupewedwa panthawi ya chithandizo.

Bongo

Zophatikizidwa ndi pheniramine.

Mankhwala osokoneza bongo a pheniramine amatha kudwala (makamaka ana), kusokonezeka kwa chikumbumtima, com.

Amalumikizana ndi paracetamol.

Pali chiopsezo cha kuledzera kwa okalamba komanso makamaka ana aang'ono (milandu yokhudza mankhwala osokoneza bongo ndi poizoni mwangozi ndizofala kwambiri).

Mankhwala osokoneza bongo a paracetamol amatha kupha.

Kusanza, kusanza, kukwiya, thukuta kwambiri, kupweteka kwam'mimba, nthawi zambiri kumawonekera pakatha maola 24.

Mankhwala osokoneza bongo oposa 10 g ya paracetamol mu 1 piritsi ya akuluakulu ndi ma 150 mg / kg pa kulemera kwa 1 mu ana amachititsa chiwindi cytolysis, zomwe zimapangitsa kuti likhale losakwanira komanso losasinthika, lomwe limayambitsa kuchepa kwa hepatocellular, metabolic acidosis, encephalopathy, yomwe Kenako, kumatha kubweretsa kukomoka komanso kufa.

Nthawi yomweyo, pali kuchuluka kwa ma hepatic transaminases, lactate dehydrogenase ndi bilirubin motsutsana ndi kumbuyo kwa kuchuluka kwa prothrombin, komwe kumatha kuchitika maola 12-48 mutatha kugwiritsa ntchito.

kuchipatala msanga
mtima wa paracetamol yoyambirira ya magazi m'magazi
kusiya mwachangu kwa mankhwala omwe adagwiritsidwa ntchito ndi chapamimba,
Chithandizo cha mankhwala osokoneza bongo cha bongo chimaphatikizanso kugwiritsa ntchito mankhwala a N-acetylcysteine kudzera mkamwa. Mankhwalawa ayenera kugwiritsidwa ntchito koyambirira, makamaka mkati mwa 10:00 pambuyo pa bongo.
methionine monga symptomatic mankhwala.

Zotsatira zoyipa

Kuchokera pa hematopoietic ndi lymphatic system: kuchepa magazi, sulfhemoglobinemia ndi methemoglobinemia (cyanosis, kupuma movutikira, kupweteka kwa mtima), hemolytic anemia thrombosis, hyperprothrombinemia, erythrocytopenia, thrombocytopenia, agranulocytosis, neutrophilic leukocytosis, purpura, leukopenia.

Kuchokera ku chitetezo chamthupi: anaphylaxis, anaphylactic mantha, khungu la hypersensitivity zimachitika, kuphatikiza pruritus, totupa pakhungu ndi mucous nembanemba (nthawi zambiri erythematous totupa, urticaria), angioedema, erythema multiforme (matenda a erythema multiforme (Stevens-Johnson), poizoni wa epermermal necrolysis (matenda a Lyell).

Kuchokera pakapumidwe: bronchospasm mwa odwala omwe ali ndi acetylsalicylic acid ndi ena NSAID.

Kuchokera m'mimba: pakamwa youma, nseru, kutentha mtima, kusanza, kudzimbidwa, kupweteka kwa epigastric, kutsegula m'mimba, chiwindi chokwanira, kuwonjezeka kwa michere ya chiwindi, nthawi zambiri popanda chitukuko cha jaundice, hepatonecrosis (mphamvu yodalira mlingo).

Kuchokera ku endocrine system: hypoglycemia mpaka hypoglycemic chikomokere.

Kuchokera ku dongosolo lamanjenje: kawirikawiri - kupweteka mutu, chizungulire, kugona tulo, kusowa tulo, kusokonezeka, kuyerekezera zinthu m'magazi, mantha, kunjenjemera, nthawi zina - chikomokere, kukokana, kukomoka, kusinthika kwa machitidwe, kuchuluka kwa kusokonekera, kusasamala ndi kukumbukira, kusokoneza, makamaka odwala okalamba zaka.

Kuchokera pamtima: munthawi zina - tachycardia, myocardial dystrophy (njira yodalira mlingo wa nthawi yayitali), orthostatic hypotension.

Kuchokera kumbali ya kagayidwe: kagayidwe kachakudya matenda a zinki, mkuwa.

Kuchokera pamikodzo: kusungika kwamikodzo komanso kuvuta kukodza, aseptic pyuria, colic.

Pa khungu: chikanga

Kuchokera kumbali ya ziwalo zamasomphenya: maso owuma, mydriasis, malo operewera.

Pogwiritsa ntchito kwa nthawi yayitali mulingo waukulu: kuwonongeka kwa zida zama impso, makristali, mapangidwe a mkodzo, cystine ndi / kapena oxalate calculi mu impso ndi kwamkodzo, kuwonongeka kwa zida zapakhungu (hyperglycemia, glucosuria) komanso kusokonekera kwa glycogen.

Kuyanjana ndi mankhwala ena ndi mitundu ina yoyanjana

Chifukwa cha kukhalapo kwa pheniramine, Mowa umachulukitsa mphamvu ya sed ₁ blockers, kotero muyenera kupewa kuyendetsa magalimoto kapena kugwira ntchito ndi zina. Pa chithandizo, kumwa zakumwa zoledzeretsa ndi kugwiritsa ntchito mankhwala okhala ndi ethyl mowa kuyenera kupewedwa.

Kuphatikiza kuyenera kukumbukiridwa.

Chifukwa cha kukhalapo kwa pheniramine, kusunthika kwina komwe kumatha kuyambitsa kupsinjika kwa dongosolo lamkati, monga morphine derivatives (analgesics, suppressants ya chifuwa, ndi mankhwala othandizira), antipsychotic, barbiturates, benzodiazepines, anxiolytics, kupatula benzodiazepines (mwachitsanzo meprobamate) , mapiritsi ogona, antidepressants sedative (Amitriptyline, doxepin, mianserin, mirtazapine, trimipramine), sedative N ₁ -blockers, antihypertensive agents apakati, baclofen ndi thalidomide.

Chifukwa cha kukhalapo kwa feniramine, mankhwala omwe ali ndi mphamvu yofanana ndi atropine, monga: imipramine antidepressants, atropine N yambiri ₁ blockers, anticholinergics, antiparkinsonia mankhwala, atropine antispasmodics, disopramide, phenothiazine antipsychotic ndi clozapine atha kuwonjezera osafunikira atropine zotsatira, monga posungira kwamikodzo, kudzimbidwa komanso pakamwa pouma.

Teraflu: zikuchokera, pharmacological kanthu

Chidachi chimapezeka mu mawonekedwe a ufa, mapiritsi, mafuta ndi mafuta opaka pakamwa. Muli paracetamol, pheniramine maleate ndi ascorbic acid.

Mankhwalawa ali ndi mawonekedwe oyenera, omwe amachititsa kuti asangokhala mankhwala ozizira, komanso amalola kuti aphatikizidwe ndi mankhwala ena a gulu lomwelo la pharmacological.

Ufa uwu ndiwopadera, motero amachotsa zizindikiro zonse za chimfine ndi chimfine wamba, ngakhale ndi shuga. Chifukwa chake, mothandizidwa ndi mankhwala, mutha kuchotsa chifuwa, kutentha thupi, mphuno ndi khosi. Komanso, mankhwalawa amathandizira chitetezo cha mthupi, motero imathandizira kuchira.

Nthawi zambiri, Teraflu, monga Fervex, imagwiritsidwa ntchito popanda shuga pamatenda monga:

hay fever
chimfine
sinusitis
rhinopharyngitis,
ozizira
rhinitis
Rhinorrhea
rhinosinusopathy ndi zina.

Ponena za zizindikiro, mankhwalawa ali ndi vasoconstrictor (phenylephrine), immunostimulating (vitamini C), antipyretic, analgesic (paracetamol), komanso anti-allergenic effect (pheniramine).

Ubwino wa mankhwalawa ndikuti ndizosiyana mawonekedwe ndi mphamvu yowonetsera, zomwe zimaloleza odwala kusankha njira yabwino kwambiri.

Koma nthawi zambiri, zokonda zimaperekedwa kwa iwo omwe zakumwa zotentha zimakonzedwa, chifukwa ndi zothandiza komanso zosavuta kugwiritsa ntchito.

Malangizo ogwiritsira ntchito mankhwalawa

Paketi imodzi ya ufa imatengedwa maola anayi aliwonse. Komabe, masana simumatha kumwa mopitilira matumba 4.

Musanagwiritse ntchito, malonda ake ayenera kusungunuka mu kapu ya madzi owiritsa. Ndikofunika kudziwa kuti odwala matenda ashuga sayenera kuwonjezera shuga pakumwa.

Mankhwalawa amaloledwa kumwa nthawi iliyonse masana. Komabe, imakhala ndi mphamvu yokwanira ngati mumamwa musanagone.

Kumwa mankhwalawa kwa masiku opitilira 5 otsatana kuli koletsedwa. Kuphatikiza apo, kugwiritsidwa ntchito kwake kumaloledwa kokha kuyambira azaka khumi ndi ziwiri.

Ndi zizindikiro zoonekeratu za chimfine kapena chimfine, mutha kusankha mankhwalawa osati molingana ndi kuchuluka kwa achire, komanso kulawa. Ndipo mulingo woyenera kwambiri wa paracetamol (325 mg) umakhala ndi analgesic komanso antipyretic kwambiri.

Mwa mitundu yayikulu yamatenda oyambitsa kupuma kwamankhwala, mutha kugwiritsa ntchito Teraflu Extra, yomwe imakhala ndi kukoma kwa sinamoni ndi apulo. Monga gawo la mtundu wamtunduwu, pali mlingo wowirikiza wa zomwe zimagwira (650 mg). Izi zimakuthandizani kuti muchepetse kutentha msanga komanso kuti muchepetse kuchuluka kwa matendawa, osatinso zovuta za matenda.

Komabe, kugwiritsa ntchito mankhwalawa ngati ufa sikuvuta nthawi zonse, chifukwa ambiri odwala matenda ashuga, ngakhale ali ndi chimfine, amatha kupita kuntchito.

Potere, amatha kugwiritsa ntchito mapiritsi a Teraflu.

Fervex: zikuchokera, achire zotsatira, zoyipa ndi contraindication

Fervex ndi ufa wopukutira wokhala ndi mtundu wowala wa beige. Sachet imodzi imakhala ndi paracetamol (500 mg) pheniramine maleate (25 g) ndi vitamini C (200 mg). Aspartame imagwiritsidwa ntchito ngati shuga.

Maziko a mankhwalawa ndi kuphatikiza kwa mankhwala othandiza omwe amachotsa zizindikiro za chimfine. Chifukwa chake, mutamwa chakumwa chotentha, kutentha kumachepa, kupweteka pakhosi ndi m'mutu kumachepa, kutupa kumatsitsimuka ndikukupukusani mphuno ndi kutsomeka.

Zizindikiro zogwiritsa ntchito Fervex ndizofanana ndi Teraflu.

Ponena za zoyipa, mutatha kumwa mankhwalawa, kudzimbidwa, kugona, kusokonezeka kwa kukumbukira, kuwonongeka kungachitike. Kusungika kwamtsempha, kusokonezeka kwa malo okhala, pakamwa youma ndikothekanso, ndipo odwala okalamba amakhala osazindikira. Pafupipafupi, wodwalayo amatha kudwala matendawa (urticaria, totupa), nthawi zina aimpso, thrombocytopenia, agranulocytosis, ndi kuchepa kwa magazi m'thupi la shuga.

Zoyipa pa kugwiritsa ntchito Fervex ndi:

chizolowezi chopanga magazi,
Hypersensitivity pamagawo a mankhwala,
kutseka-kotsekera glaucoma,
zaka mpaka 15
uchidakwa
Prostate adenoma,
phenylketonuria,
aimpso ndi chiwindi kulephera.

Malangizo ogwiritsira ntchito

Mutha kumwa mpaka ma 2-3 sachets patsiku. Koma choyamba, zomwe zili phukusili ziyenera kusungunuka mu kapu yamadzi ofunda kapena ozizira.

Malangizo osagwiritsa ntchito shuga a Fervex kuti mugwiritse ntchito umati muyezo woyamba wa mankhwalawa ndi wabwinobwino kutulutsa matenda akangoyamba kumene. Njira yothetsera vutoli iyenera kuledzera mukangomaliza kukonzekera, ndipo nthawi yayitali pakati pa Mlingo uyenera kukhala osachepera maola 4. Kutalika kwa mankhwala sikupitilira masiku atatu.

Ngati mulingo wapitirira, paracetamol ndi feniarmin zimatha kukhala ndi poizoni m'thupi, zomwe zimawonetsedwa ndi kusokonezeka kwa chikumbumtima, kupweteka komanso ngakhale kukomoka.

Mankhwala osokoneza bongo amatha kuchitika ngati mlingo wa paracetamol wa munthu wamkulu uposa magalamu 4, omwe angayambitse hepatonecrosis. Zizindikiro za kuledzera zimatha tsiku litatha kumwa Fervex. Chithandizo cha mankhwalawa chimakhala cha kupweteka kwam'mimba komanso makonzedwe a mtsempha wa N-asethylcysteine, methionine ndi dalili.

Mtengo wa Fervex wopanda shuga (ma PC 8. Pakiti iliyonse) umachokera ku 270 mpaka 600 rubles. Mtengo wa Teraflu ufa umatengera kuchuluka kwa mapaketi: ma 4 ma PC. - kuchokera 200 p., ma PC 10. - 380 ma ruble.

Kanemayo munkhaniyi apereka malangizo atsatanetsatane amomwe angachiritsire chimfine cha matenda ashuga.