Gemfibrozil: malangizo ogwiritsira ntchito, analogi, mitengo ndi malingaliro

Wothandizirana ndi lipid, wotsitsa lipoprotein lipase, amachepetsa kuchuluka kwa TG, cholesterol yathunthu, VLDL ndi LDL m'magazi (mpaka pang'ono), amachepetsa mapangidwe a TG mu chiwindi, amalepheretsa kapangidwe ka VLDL ndikuwonjezera chilolezo chawo, kumawonjezera mapangidwe a HDL ndi anti-atherogenic athari. Imalepheretsa zotumphukira za lipolysis, kumachulukitsa kuchuluka kwa mafuta am'mafuta a chiwindi, motero kumachepetsa kaphatikizidwe ka TG m'chiwindi. Amachepetsa kuphatikiza mafuta achilengedwe ambiri mu TG yomwe yangopangidwa kumene, imathandizira kufalikira ndikuchotsa cholesterol ku chiwindi ndikuwonjezera kuchulukana kwake ndi bile.

Kukhazikika kwa zinthu kumachitika pambuyo pa masiku 2-5, ndipo pazotheka masabata anayi pambuyo pake.

Zotsatira zoyipa

Kuchokera kwamanjenje: chizungulire, kupweteka mutu, kutopa kwambiri, kukomoka, paresthesia, kugona, kukhumudwa.

Kuchokera pamimba: kukamwa kouma, kuchepa kwa chakudya, kutentha kwa mtima, mseru, kusanza, gastralgia, kupweteka kwam'mimba, kuphwanya mseru, kutsegula m'mimba kapena kudzimbidwa, hyperbilirubinemia, ntchito yowonjezera ya hepatic transaminases ndi alkaline phosphatase, cholelithiasis.

Kuchokera ku minculoskeletal system: myasthenia gravis, myalgia, arthralgia, rhabdomyolysis.

Kuchokera hemopoietic ziwalo: leukopenia, kuchepa magazi, m`mafupa hypoplasia.

Kuchokera ku genitourinary system: kutsika kwa potency ndi / kapena libido.

Thupi lawo siligwirizana: zotupa pakhungu, dermatitis.

Zina: hypokalemia, alopecia, kuwonongeka kwa mawonekedwe, synovitis.

Malangizo apadera

Pa mankhwala, kuwunika mwadongosolo ma lipids a m'magazi ndikofunikira (ngati chithandizo sichikuyenda bwino, kuchotsedwa kwasonyezedwa kwa miyezi itatu).

Pakukonzekera chithandizo komanso mukamaliza, muyenera kudya zakudya zapadera za hypocholesterol.

Ndi chithandizo chakanthawi yayitali, kuwunika mwanjira ya magazi ndi zotupa za chiwindi ndikofunikira (ndikutembenuka kwakukulu kwa zitsanzo za "chiwindi" kuchokera ku chizolowezi, chithandizo chimayimitsidwa mpaka chitasintha).

Ngati mwaphonya mlingo wotsatira, muyenera kumwa mosachedwa, koma osachulukitsa ngati nthawi yakwana mlingo wotsatira.

Ngati kupweteka kwa minofu kumachitika, kupezeka kwa myositis (kuphatikizapo kutsimikiza kwa CPK) kuyenera kupatulidwa. Ngati wapezeka, mankhwalawo amathetsedwa.

Ngati cholelithiasis yapezeka, chithandizo chatha.

Kuchita

Zosagwirizana ndi lovastatin (kwambiri myopathy ndi kulephera kwaimpso kumatha kuchitika).

Amachepetsa mavuto a ursodeoxycholic ndi chenodeoxycholic acid chifukwa cha kuchuluka kwa mafuta m'thupi ndi bile.

Imawonjezera zotsatira za anticoagulants osalunjika, mankhwala amkamwa a hypoglycemic (zotumphukira za sulfonylurea).

Pogwiritsa ntchito mankhwala oletsa kubereka, ngozi ya mafuta osokoneza bongo imachuluka.

Mankhwala

Gemfibrozil adapezeka chifukwa chofufuza zinthu zamtundu wa clofibrate zokhala ndi poizoni wochepa. Gemfibrozil adatsimikizira kuti ali ndi poizoni wocheperako ndipo, nthawi yomweyo, wogwiritsa ntchito lipid-kuchepetsa wambiri omwe amachepetsa zomwe zili ndi VLDL (otsika kwambiri opanga lipoproteins) m'magazi a odwala omwe ali ndi hypertriglyceridemia (okwera magazi triglyceridemia) omwe samayankha pazakudya ndi mankhwala ena otsitsa a lipid. Kuphatikiza apo, kumawonjezera ndende ya HDL (lipotroteins high).

Zizindikiro zogwiritsidwa ntchito

Gemfibrozil amalembedwa kwa odwala omwe ali ndi hypertriglyceridemia chifukwa chokana mankhwala azithandizo ndi mankhwala ena ochepetsa lipid. Pankhani ya hyperchilomicronemia (magazi ochulukirapo a ma chylomicrons / tinthu tomwe timakhala ndi mafuta osagwirizana ndi mulingo wa 1 μm chifukwa cha kuchepa kwa lipoprotein lipase (enzyme yomwe imawononga lipoprotein), mankhwalawa ndi osathandiza.

Zotsatira zoyipa

Gemfibrozil nthawi zambiri imalekeredwa. Kupweteka kwam'mimba (kupweteka kwam'mimba, nseru, kutsekula m'mimba) ndizotheka. Nthawi zina, kuchepa kwa magazi m'thupi (kuchepa kwa hemoglobin m'magazi), leukopenia (kuchepa kwa maselo oyera a magazi). Monga clofibrate (koma yocheperako) imatha kupangitsa kuti ma gallstones apangidwe.

Contraindication

Gemfibrozil ndi ophatikizidwa mwa odwala, amayi apakati, komanso anthu omwe ali ndi matenda aliwonse a gallbladder kapena cirrhosis ya chiwindi.

Chenjezo amaperekedwa kwa aimpso ndi kwa chiwindi kuchepa, cholecystitis, hypertriglyceridemia.

Gemfibrozil potentiates (imakulitsa) mphamvu ya anticoagulants (othandizira omwe amaletsa kuwundana kwa magazi), ayenera kugwiritsidwa ntchito limodzi mosamala moyang'aniridwa ndi dokotala.

Mawonekedwe ndi kipimo

Gemfibrozil (dzina lamalonda) ndi mankhwala ochepetsa mphamvu ya lipid ogwirizana ndi zotumphukira za fibroic acid (malinga ndi radar). Dzina la pharmacological la gulu la mankhwalawa ndi mafupa. Mankhwala kumawonjezera ntchito ya enzyme lipoprotein lipase, amene amachepetsa ndende ya seramu cholesterol. Gemfibrozil imalepheretsa kupanga cholesterol "choyipa" (LDL, HDL), ndikuwonjezera zomwe zili "kachigawo" kabwino, kamene kali ndi anti-atherogenic katundu (HDL).

Dziko lopanga mankhwalawa ndi Russian Federation, Netherlands kapena Italy. Amapezeka mu mawonekedwe a makapisozi ophimbidwa ndi chipolopolo cha edible gelatin. Chibotili chilichonse chimakhala ndi 300 kapena 600 mg ya yogwira - gemfibrozil. Mitundu ya Mlingo imakhala ndi maselo a foil ndi makatoni amakhadi okhala ndi zidutswa 30 kapena 20, motero.

Zolemba zogwiritsira ntchito

Kuchiza ndi mankhwalawa pa nthawi yoyembekezera komanso nthawi yoyamwitsa imatsutsana. Komanso, simungatenge zotumphukira za fibroic acid mwa odwala omwe ali ndi vuto la chiwindi ndi impso. Ana ochepera zaka 18 sakhala mankhwala osasakanizidwa chifukwa cha kusachita bwino kwawo komanso chitetezo m'gululi.

Gemfibrozil analogues

Monga mankhwala ambiri, mankhwalawa ali ndi cholowa m'malo. Gemfibrozil amafotokozera za yogwira thunthu ndi zamankhwala zochita za Gavilon, Ipolipid, Normolip, Regp. Zina ndizotsika mtengo kuposa mankhwala oyambira. Zomwe zili bwino Gemfibrozil kapena m'malo mwake, wodwala aliyense amasankha yekha.

Kugwiritsa Ntchito

Pakati pa akatswiri a mtima ndi odwala omwe amamwa mankhwalawa, ali ndi mbiri yabwino. Amayang'anitsitsa kutsika kwake kwapang'onopang'ono kwa lipid, kulekerera kwabwino. Ogula osakhutira ndi mtengo wake wokwera komanso kusakhoza kufikirika. Ngakhale ndemanga zabwino za mankhwalawa, simuyenera kuyamba kumwa popanda kuonana ndi katswiri. Dotoloyo amalemba mankhwala a anticholesterol potengera kusanthula deta, komanso momwe wodwalayo alili!

Mankhwala a Omacor

Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.

Mankhwala Omacor amagwiritsidwa ntchito ngati mankhwala popewa matenda amtima, makamaka, atherosulinosis. Mafuta acids ofunikira (vitamini F, ndiye kuti, omega-3 ndi omega-6), omwe ndi gawo la mankhwalawo, sangapangidwe chifukwa cha kagayidwe ndipo amalowa mthupi ndi chakudya.

Zizindikiro ndi contraindication

Ngati mwayikidwa gemfibrozil, malangizo ogwiritsira ntchito ayenera kuphunziridwa bwino. Pamaziko ake, osati kuchuluka kwa kuchuluka kwa mankhwala ndi nthawi yokhazikika yotsimikizika, komanso zoletsa kugwiritsa ntchito ndikukhazikitsidwa.

Zizindikiro zazikulu zogwiritsidwa ntchito:

1. Mankhwala akuwonetsedwa kuti agwiritsidwe ntchito kwa odwala omwe ali ndi kuchuluka kwa magazi lipids, omwe sangathe kuchotsedwa pakudya.
2. Mankhwalawa amagwiritsidwa ntchito popanga zovuta zina zamatenda ena zomwe zimayambitsa kuchuluka kwa plasma cholesterol.
3. Gemfibrozil amalembedwa kuti athetse mtundu wa triglycerides, makamaka posakhala ndi zotsatira zabwino kuchokera kuzakudya komanso kugwiritsa ntchito mankhwala ena ochepetsa lipid.

Mankhwalawa ali osavomerezeka kwa odwala onse, popeza pali zoletsa zina pa nthawi yoikidwiratu. Izi zikuphatikiza ndi izi:

• matenda a chiwindi ndi impso mu gawo la kubwezeretsa,
• nthawi yobala mwana ndi kuyamwitsa,
• kuchuluka kwakukulu kwa ntchito ya hepatic transaminases,
• wazaka 18.

Kwa anthu omwe ali ndi vuto la chiwindi chakumwa choledzeretsa, atasinthika ziwalo kapena ziwalo, komanso ndi kufanana kwa ma immunosuppressants, komanso atachitapo kanthu pakuchita opaleshoni iliyonse, kulimbikitsidwa kwa Gemfibrozil sikuvomerezeka. Komabe, pamaso pa zisonyezo zovuta zogwiritsidwa ntchito ndi mankhwalawa, kugwiritsidwa ntchito kwake ndikotheka, koma kokha moyang'aniridwa ndi achipatala.

Mankhwala ali osavomerezeka kuti mugwiritse ntchito munthu amene akumwa chifukwa chogwira ntchito kapena mankhwala othandizira a Femfibrozil. Izi zikuwopseza kukhala ndi hypersensitivity reaction mu mawonekedwe a zidzolo, atopic rhinitis, dermatitis komanso kufalikira kwa matenda ena okhalitsa, monga psoriasis.

Kugwiritsa ntchito gemfibrozil kumatha kuyambitsa zovuta. Nthawi zambiri, mavuto amayamba chifukwa cha m'mimba. Zimatha kukhala: kutaya chidwi, kusanza, kusanza, kutsegula m'mimba, kuwonjezeka kwa michere ya chiwindi.

Osati pafupipafupi, kupweteka mutu, chizungulire, kutopa kwambiri, kuchepa kwa libido amalemba. Nthawi zina, kupweteka m'misempha ndi molumikizana. Kupezeka kwamasintha ang'onoang'ono m'magulu a magazi sikuphatikizidwa.

Pakachitika zovuta, kugwiritsa ntchito mankhwalawa kuyenera kuyimitsidwa nthawi yomweyo. Muyenera kufunsa dokotala kuti musankhe othandizira ena a lipidemic omwe ali ndi vuto lofananalo. Ma analogi a Gemfibrozil ndi Gavilon, Normolip, Regp, Ipolipid, ndi zina zotero. Musasankhe mankhwala nokha kuti mupewe kukula kwa zovuta.

Mawonekedwe akugwiritsidwa ntchito

Gemfibrozil amachepetsa cholesterol kokha ngati amagwiritsidwa ntchito nthawi zonse. Muyenera kumwa mapiritsi 1-2 kamodzi patsiku, ndikofunika kuti musaphonye kamodzi. Ndi cholesterol yayikulu, adokotala amatha kusankha pakufunika kochulukitsa mapiritsi azomwe amagwiritsidwa ntchito kamodzi, ndipo nthawi zina, amachepetsa. Izi zitha kutsimikizidwa kokha ndi mayeso a labotale.

Kuti mukwaniritse kutsitsa kwa lipid, simuyenera kumangomwa Gemfibrozil, komanso kuwunikira kuchuluka kwa cholesterol m'magazi. Izi ndizofunikira kuti athe kuwunikira moyenera kuchuluka kwa mphamvu ya mankhwalawa. Pakusowa zotsatira zotchulidwa, kusintha kosankhidwa kukufunika.

Kuyang'anira magazi a biochemical ndikofunikira pa matenda a chiwindi. Chifukwa chake, nkwanthawi yake kudziwa kuwonjezeka kwa ntchito ya transaminase ndikusiya mankhwalawo kuti magazi asawonongeke.

Mukamachita maphunziro othandizira, wodwalayo amafunika kutsatira zakudya zochepa zamafuta. Pewani zakudya zamafuta ndi nyama yokazinga. Onjezani kudya zakudya zopatsa thanzi komanso zakumwa.

Popereka mankhwala a gemfibrozil, wodwalayo ayenera kudziwitsa adokotala za kugwiritsa ntchito mankhwala ena. Mankhwala ena saphatikizana ndi mankhwala ochepetsa lipid ndipo amatha kuchepetsa kapena mosemphanitsa - amathandizanso kugwira ntchito kwawo. Gemfibrozil satengedwa molumikizana ndi anticoagulants mwachindunji, chenodeoxycholic acid, ndi othandizira othandizira a lovastatin.

Zochita zamankhwala

Pambuyo potenga Omacor, zigawo zake zimatengedwa ndi maselo amisempha ndipo, ndikulowa m'chiwindi, zimapanga zinthu zofunikira zomwe zimapatsa minofu ya mtima (myocardium), zimathandizira kulimbitsa makhoma amitsempha yamagazi, kutseka mapangidwe amitsempha yamagazi, ndikulepheretsa kukula kwa atherosulinosis. Izi zimachitika chifukwa cha kuchepa kwamlingo wa triglycerides - zigawo za gulu la lipids (mafuta). Komanso kuchuluka kwa cholesterol yoyipa, yomwe imaperekedwa kudzera m'magazi ndi ma lipoproteins otsika, amachepetsedwa.

Omacor amateteza minofu ya mtima mu vuto la kuthamanga kwa magazi mthupi. Kudziwikitsa kwa mankhwalawo kwanthawi yayitali m'thupi, mwayi wobwereza matenda amtima ndi sitiroko, komanso zinthu zosintha mosagwirizana ndi vuto la mtima, umachepetsedwa kwambiri.

Mankhwalawa amathandizira kuwonjezeka pang'ono pa coagulability wamagazi, omwe samakhudzana ndikupatuka kuchoka pachiwonetsero ichi, ndikuwongolera madzi amadzimadzi a m'magazi. Pogwiritsa ntchito kukakamiza, Omacor amatsitsa ngati pakufunika.

Kugwiritsa

Malinga ndi malangizo ogwiritsira ntchito, kapisolo wa Omacor amatsukidwa ndi madzi pakudya. Mlingo wa tsiku ndi tsiku pafupifupi 1 g (kapisozi imodzi), mwachitsanzo, kupewa matenda a mtima. Hypertriglyceridemia imaphatikizapo kutenga makapisozi awiri. Ngati zotsatira zake sizichitika, ndiye kuti muyezowo umachulukitsidwa.

Osavomerezeka kuti musagwiritse ntchito mankhwalawa mankhwala osokoneza bongo, chifukwa zoyipa zimatha kuoneka: kusokonezeka kwam'mimba, nseru, kuyabwa khungu, mutu. Kukhazikika kwa zochitika zovutazi kumathetsedwa ndi mankhwala oyenera.

Kutalika kwa mankhwalawa kumatengera momwe wodwalayo alili ndi kupezeka kwake, kupezeka kwa matenda olimba ndi zinthu zina zambiri.

Kwa oyembekezera

Mankhwala alibe umboni wokwanira wokonda Omacor panthawi yapakati, chifukwa chake, kwa amayi omwe amakhala ndi mwana, mankhwalawa amatsutsana. Pali nthawi zina pomwe Omacor ndiye mankhwala okhawo omwe mayi wodziwitsa ayenera kubereka. Kenako dokotalayo amapanga chisankho cholondola ndipo mosamala kwambiri amafotokoza zamankhwala, pofufuza momwe wodwalayo alili.

Ngati kufunika kwa Omacor kwakhazikika kwa mayi woyamwitsa, ndiye kuti mwanayo ayenera kuyamwa (kwakanthawi kapena pamapeto pake - adotolo adzaganize).

Kodi ndingalowetse bwanji mankhwalawa

Pazogulitsa zamankhwala, zotengera zochokera pazoyambira zimagawidwa:

• analogues (ali ndi zinthu zina zomwe zimagwira ntchito zomwe zili zofanana ndi mankhwala oyamba malinga ndi zomwe zimachitika mthupi),
• masinthidwe (okhala ndi chimodzi kapena zingapo zofanana ndi zoyambirira),
• zamagetsi (kupanga kwawo, mtundu wa zida zopangira zomwe amagwiritsa ntchito komanso mayesowo amatha kupitirira kuwongolera kochepa, chifukwa chake chitetezo chogwiritsa ntchito mankhwalawa nthawi zambiri chimakhala chikaikira). Mitundu yodalirika kwambiri imapangidwa ndi opanga mankhwala oyamba, chifukwa amagwiritsa ntchito zida zomwezo komanso kayendetsedwe ka mafakitale.

Dokotala amatha kupereka mankhwala ofanana, analogue, kapena generic kwa wodwala pazifukwa zitatu:

• mukakumana ndi zovuta pambuyo pakutenga Omacor, yomwe imawoneka motsutsana ndi matenda omwe amakumana nawo,
• ngati Omacor sapezeka m'mafakisi (ndipo izi zitha kuchitika), ndipo mankhwalawo akufunika mwachangu,
• chifukwa cha mtengo wotsika kwambiri wa mankhwalawa. Dokotala wodziwa bwino, kupereka mankhwala, mwachitsanzo, generic, adzakopa chidwi cha wopangayo kuti asagulitse zabodza.

Mapangidwe omwe ali pafupi ndi Omacor ndi ofanana ndi omega-3 triglycerides, omwe nthawi zambiri (osadziwa kuti amachokera pazinthu zake) amatchedwa analogue.Ma Synonyms amakhalanso ndi mankhwala: Vitrum Cardio, mafuta a nsomba a Amber Drop, omeganol, omeganol forte, mafuta a Golden Fish khanda, biafishenol, mafuta a cod chiwindi "Lisi", epadol, eikonol, komanso mankhwala, omwe mayina ake ali ndi kuwonjezera kwa "omega-3" (perfoptin, wapadera, pikovit, ma tabu angapo a Intello Ana, doppelgerz asset).

Pali ma analogi ambiri a Omacor, ndipo onse, monga ma syonyms, ali ndi mtengo wotsika poyerekeza ndi woyamba. Zina mwazinthuzi ndi: angionorm, tribestan, lipantil, ezetrol, alkolex, arachidene, roxer, octolipene, peponen, lysivitis C, atheroclephite, splatinat, chisangalalo, super alistat, phytoTransit, orsoten slim, expon Lipon.

Mankhwala obadwa nawo amatha kukhala ndi mayina a analogues, kapangidwe kake ndiofanana ndi choyambirira, koma osati nthawi zonse. Wopeza, monga lamulo, ndi wosiyana, chifukwa chomwe thupi limakumana ndi mkwiyo wamakoma am'mimba kapena chifuwa.

Njira yopangira zida zamagetsi ndi yosavuta kwambiri, makamaka kupondaponda imagwiritsidwa ntchito, osati kumata. Ngakhale mankhwala omwewo omwe ali gawo la mankhwalawa, koma adutsa matekinoloje osiyanasiyana opanga mitundu, amasiyanasiyana kwambiri, motero kugwiritsa ntchito mankhwalawo moyenera.

Mwanjira ina, kusowa kwa patent yopanga kumapereka mphamvu kwa ena, zomwe pamapeto pake zimakopa ogula pamtengo wotsika. Komabe, ndi chithandizo chosalekeza, pofuna kuteteza komanso kukwaniritsa zotsatira zomwe mukufuna, ndibwino kuti musankhe mankhwalawo oyambira.

Wopanga wamkulu wa Omacor ndi Abbott Products GmbH, Germany, yemwe ali ndi nthambi ndi maofesi oimira padziko lonse lapansi.

M'mafakisi ku Moscow mutha kugula mankhwala opangidwa ndi GM Peck, Denmark kwa ma ruble 1490. Catalent U.K. Swindon Encaps, Great Britain ipereka ma Muscovites Omacor a 1596-1921.86 rubles, ndi Danish wopanga Banner Farmacaps Europe B.V. - za 1617-1770 rubles. Kampani yopanga mankhwala ku America Cardinal Health imapatsa Omacor ma ruble 1677-2061. Mitengo yonse yomwe yatchulidwayi ndi yonyamula makapisozi olemera 1000 mg mu 28 zidutswa.

Malinga ndi akatswiri a mtima, Omacor amathandizira thupi kukhala ndi matenda amtima, kuchepetsa kwambiri zotsatira zosasinthika, zomwe kafukufuku wa sayansi wamankhwala amatsimikizira motsimikiza.

Pambuyo akuvutika ndi myocardial infaration mwa odwala Omacor mu mankhwala, kusintha kwa mtima kumawonedwa. Kuphatikiza apo, madotolo amawona kuchepa kwa mafuta m'thupi (cholesterol), kuchuluka kwa kagayidwe, kulimbitsa tsitsi ndi misomali, kusintha khungu ndi maonekedwe ambiri, kunenepa. Kulandila kwa Omacor moyang'aniridwa ndi katswiri kumathandizanso zochitika za ubongo, kumalimbitsa minofu.

Odwala kuwona kuchotsedwa kwa vuto mu mawonekedwe a chizungulire pambuyo mlingo kuchepetsa. Pankhaniyi, zotsatira zazikulu pambuyo poti vuto la mtima lidagwira, Kuphatikiza apo, chidziwitso cha coagulation chibwerera mwakale.

Zomwe zimagwiritsidwa ntchito ndi mankhwala

Pomwe zakudya zambiri zokhala ndi omega-3 polyunsaturated fat acids zimapangidwa ndi mafuta a triglycerides (mafuta osalowerera), ku Omacor ma asidi awa ali ndi mawonekedwe osiyana ndi ma cell (mawonekedwe a esters) omwe amatha kuphatikizidwa ndi membrane (membrane) wamaselo am'mimba, chilolezo cha potaziyamu, magnesium, calcium, yomwe imateteza ku arrhythmias.

Omacor ndiye mankhwala okhawo omwe amakhala ndi mafuta ambiri okhala ndi mafuta oyeretsa kwambiri, ophatikiza 90% ya zomwe zili pamankhwala. Kapangidwe kofunika ka omega-3 kumapangitsa kuti mugwiritse ntchito bwino mankhwalawa pophatikiza mankhwala othandizira kupewa myocardial infarction.

Kulekerera kwabwino kwa Omacor osakanikirana ndi zotsatira zabwino zabwino kumayambitsa mankhwalawa pakati pazofunikira pa matenda a mtima ndi mtima.

Lembani ndemanga yoyamba

Captopril imakhala ndi hypotensive, imagwiritsidwa ntchito kwambiri pakati pamagulu osiyanasiyana odwala kuti achepetse kuthamanga kwa magazi, kusintha kwa mtima ndi kugunda kwa mtima. Mankhwalawa ali ndi mphamvu, chifukwa chake, ayenera kugwiritsidwa ntchito molingana ndi malangizo ndi malangizo a dokotala. Kulephera kutsatira malingaliro omwe amagwiritsidwa ntchito nthawi zambiri kumadzetsa mavuto obwera chifukwa cha moyo ndi thanzi la wodwalayo.

Kufotokozera ndi kapangidwe

Mapiritsiwo amakhala ndi mawonekedwe oterera, opindika m'mphepete, fungo linalake. Mbali imodzi, mizere iwiri ikuwoneka. Mtundu wa mankhwalawo ndi zoyera kapena zoyera.

Chofunikira chachikulu chomwe chimaphatikizidwa ndikuphatikizidwa ndi capopril. Zolemba zake zimatengera mtundu wa kumasulidwa. Mwa zina zothandizira ndi talc, magnesium stearate, lactose, povidone ndi zinthu zina.

INN (dzina losavomerezeka padziko lonse lapansi) - Captopril.

Mankhwala

Captopril ndi mankhwala osokoneza bongo a antihypertensive, omwe amakhudzanso ACE zoletsa. Enzyme angiotensin II ili ndi mphamvu ya vasoconstrictor m'thupi, kuphipha kwa minofu yosalala ya mitsempha ndi mitsempha, yomwe imapangitsa kuchuluka kwa magazi. Captopril imalepheretsa kusintha kwa angiotensin I kukhala angiotensin II. Katunduyu wa mankhwala amalola kuchepetsa kupsinjika, kuthana ndi nkhawa m'matumbo amtima, kusintha momwe munthu alili, komanso kupewa mavuto obwera chifukwa cha mtima. Kuphatikiza apo, chida chimathandizira kukonza magazi mu impso.

Pharmacokinetics

Mankhwala a Captopril atalowa m'mimba amatengeka mwachangu kuchokera m'mimba, chifukwa chomwe achire chimachitika msanga. Zakudya zomwezi munthawi yomweyo zimachepetsa. The pazipita ndende yogwira zigawo zikuluzikulu m'magazi zimawonedwa pambuyo 1 - 1, 5 maola.

Metabolism imachitika m'chiwindi. Mankhwalawa amachotsa impso. Zosasinthika - kuchokera 40 mpaka 50% pazinthu. Chotsalira chili munjira ya metabolites. Ndi kulephera kwa aimpso, kuwerengera kumatha kuchitika, ndiye kuti, zophatikizika za gawo lomwe limagwira.

Zizindikiro zogwiritsidwa ntchito

Kodi chimathandiza ndi chiyani? Perekani njira yothandizira kuti muime mavuto, osachepetsa magazi. Zizindikiro zama Captopril ndi awa:

• kuchuluka kwa matenda a impso,
• kuchuluka kwa kupsinjika, kutengera kwa zomwe sizikudziwika,
• matenda oletsa kuthana ndi mankhwala,
• Cardiomyopathies odwala
• kusintha kwa mtima pakukanika,
• matenda ashuga,
• autoimmune nephropathies,
• kukanika kwa mtima kumanzere kwamtima chifukwa cha kulowerera kwa mtima,
• matenda oopsa odwala ndi bronchial mphumu.

Kugwiritsa ntchito kwa captopril kuyenera kuchitika pokhapokha ngati adokotala adawauza, popeza mankhwalawo ali ndi zotsutsana zingapo.

Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.

Kwa yemwe mankhwala amatsutsana

Mankhwala omwe amafunsidwawo amagwiritsidwa ntchito kwambiri pazachipatala, koma akapatsidwa mankhwala, makompyuta a Captopril ayenera kukumbukiridwa. Izi zikuphatikiza:

• Kuchepetsa mphamvu yakuwala,
• kuphwanya sodium-potaziyamu bwino m'thupi chifukwa cha kuchuluka kwa aldosterone ndi adrenal cortex,
• kuwonongeka kwa kugwira ntchito kwa mitral valavu, kutsitsa kwake,
• ntchito yowonjezera impso,
• nthawi yobala mwana,
• chizolowezi chotupa
• myocardiopathies
• Edincke's edema,
• kuperewera kwa lactose
• nthawi yoyamwitsa,
• tsankho lanu pazinthu zomwe mankhwalawa ali,
• zaka wodwalayo asanafike zaka 18.

Kulephera kutsatira zomwe wapangidwazo pamwambapa kumayambitsa chitukuko chachikulu, kumatha kuvulaza thanzi komanso moyo wa wodwalayo.

Ndi ochepa matenda oopsa

Mankhwala a Captopril a matenda oopsa amathanso kusankhidwa ndi katswiri, kutengera mbiri ndi kuwonetsa magazi. Kutengera mzere wa mercury, mlingo wa tsiku ndi tsiku kumayambiriro kwa mankhwala nthawi zambiri umachokera ku 100 mpaka 150 mg. Mapiritsi amagawidwa ma Mlingo angapo mosiyanasiyana nthawi. Palibe kupezeka koyenera, mlingo umakulitsidwa. Kuphatikiza pa Captopril, adokotala atha kukulemberani njira zina, mwachitsanzo, okodzetsa.

Ndi kulephera kwa mtima ndi hypovolemia

Odwala omwe ali ndi matendawa amapatsidwa mankhwala kamodzi. Poyamba, odwala amamwa 6.25 - 12.5 mg. Pambuyo pa sabata, mlingo umadutsana, ndikugawikana. Pa mankhwala, ndikofunikira kuyeza kuthamanga kwa magazi. Ngati zotsatira zomwe mukufuna sizikwaniritsidwa, mlingo umakwera mpaka 60-100 mg.

Yaitali mankhwala a myocardial infarction

Captopril imagwiritsidwa ntchito masiku atatu mpaka 16 pambuyo povulazidwa. Mankhwalawa amachitika moyang'aniridwa ndi ogwira ntchito pachipatala. Choyamba, wodwalayo amapatsidwa 6.25 mg. Pambuyo pa tsiku - 12 mg, logawidwa mu 2 waukulu. Pambuyo masiku angapo - 25 mg mu 3 mgulu waukulu. Mwanjira imeneyi, mlingo umakulitsidwa mpaka 100 mpaka 150 mg. Kutalika kwa chithandizo kumatsimikiziridwa kutengera ntchito ya mtima ndi mphamvu ya kuthinikizidwa, kugunda kwa mtima ndi zizindikiro zina.

Chithandizo cha odwala matenda ashuga a Nephropathy

Odwala odwala matenda a shuga a nephropathy amawerengera 75 mpaka 100 mg wa mankhwala patsiku. Mlingo wagawidwa magawo atatu ofanana. Mapiritsi ayenera kumeza madzi okwanira. Captopril nthawi zambiri imagwiritsidwa ntchito ngati zovuta kuchitira pamodzi ndi kugwiritsa ntchito mankhwala enanso amomwe amachepetsa kuthamanga kwa magazi.

Zofunika! Zomwe zaperekedwa pamwambapa zimaperekedwa. Kugwiritsa ntchito zilizonse pazokha kungakhale koopsa thanzi.

Kukhazikika kwa achire zotsatira

Kodi Captopril amatenga nthawi yayitali bwanji komanso kumwa mapiritsi molondola? Chidacho chimapangidwa kuti chigwiritsidwe ntchito pakamwa, koma nthawi zina chimaloledwa pansi pa lilime.

Zochita za mankhwalawa zimayamba pakadutsa mphindi pafupifupi 15, zomwe zimatengera mawonekedwe a chiwalo chilichonse, kuzindikira kwa wodwalayo. Ngati wodwalayo adatenga chakudya posachedwa, zotsatira za piritsi zimatha kuchepa pang'ono. Poterepa, zotsatira zake zimachitika mphindi 15 mpaka 20.

Kugwirizana kwa Mowa

Kuphatikiza kwa captopril ndi mowa ndikosayenera kwambiri. Kuphatikizika kumeneku kumapangitsa kuchepa kwa kuphatikizidwa kwa potaziyamu ndi thupi, chifukwa zakumwa zoledzeretsa zimatsuka michereyi m'thupi. Kuperewera kwa potaziyamu kumadzetsa kuwonjezeka kwa kuthamanga kwa magazi.

Kuphatikiza apo, Captopril ndi mowa zimaloledwa kuphatikizidwa kuti muchepetse vuto lalikulu kwambiri pamaso pa anthu otenga hangover, kupatula odwala omwe ali ndi vuto la impso.

Kuyanjana kwa mankhwala osokoneza bongo

Mukamapereka mankhwala, katswiri ayenera kuganizira momwe amathandizirana ndi mankhwala ena:

• kugwiritsa ntchito munthawi yomweyo ngati wothandizirana ndi ma immunosuppressants ndi cytostatics kumawonjezera mwayi wokhala ndi leukopenia,
• Kuopseza kwa hyperkalemia kumawonjezeka ndi Captopril ndi potaziyamu wotetemera okodzetsa, mavitamini omwe ali ndi potaziyamu, zowonjezera zakudya,
• Ngati wodwala amatenga nthawi yomweyo mankhwala osapatsirana omwe angayambitse kutupa, vuto laimpso lingayambike,
• kuphatikiza kosasamala kwa captopril ndi okodzetsa kumawonjezera mwayi wokhala ndi hypotension yolimbikira,
• hypotension yayikulu imapezeka pamene Captopril imaphatikizidwa ndi mankhwala oletsa kupindika,
• Aspirin amachepetsa mphamvu ya mankhwala omwe amafunsidwa,
• amachepetsa mphamvu ya Captopril indomethacin, ibuprofen,
• munthawi yomweyo kuperekera Captopril mankhwala okhala ndi insulin kumawonjezera chiopsezo cha hypoglycemia. Izi zimachitika chifukwa cha kulolera kwakukulu kwa glucose,
• Ma inhibitors a ACE molumikizana ndi mankhwalawo omwe amafunsidwa angayambitse kuchepa kwa chikakamizo.

Ndemanga za Odwala

Galina, Donetsk
“Ndimagwiritsa ntchito magazi a magazi. Ndili ndi matenda oopsa kwa zaka zoposa 10, munthawi imeneyi ndinakumana ndi mavuto ambiri oopsa. Popewa zovuta zoyipa, ndimayesetsa kutsatira mosamalitsa mlingo womwe dokotala wamulembera. Dotolo adandiwuza kuti ndiziyezera kukakamiza nthawi zonse, kutenga piritsi limodzi ngati kuli kotheka. Mankhwala sakadandaula pano. ”

Anatoly, Moscow
"Dokotala yemwe amandidziwa ananena kuti simungamwe mankhwalawa nthawi zonse. Mankhwalawa amayenera kusungidwa ku khabati yachipatala mwadzidzidzi. Ndikulimbikira kwambiri, ndimatenga Captopril, imathandiza kwambiri, koma mankhwala ena sagwira ntchito. Palinso maulalo ake abwino - Kaptopres. Ngakhale mutu ndi kufooka zimachitika nditamwa mapiritsiwo, Captopril amathandizanso kupanikizika. ”

Nadezhda, Balashikha
“Ndinapita kwa dotolo ndikudandaula za kuthamanga kwa magazi. Ziwerengerozi zidafika 160/100. Ndili ndi zaka 57, ndakhala ndikuvutika ndi matenda oopsa kwa nthawi yayitali. Dokotala adayikapo kapitawo. Pambuyo pa kumwa mankhwalawo, kupanikizika kunatsika, koma kuyuma kosasangalatsa kunatulukira mkamwa. Kuphatikiza apo, mutu wanga udawawa. Mtsogololi ndimalingalira kusiya mankhwalawa. "

Timalankhula za Sodecor ya mankhwala yolembera mapulateleti

Kutsitsa maselo othandiza magazi m'magazi a munthu ndi vuto lotchedwa thrombocytopenia. Matendawa amadziwika ndi kukhazikika kwa magazi mphuno ndi kupindika gingival, mapangidwe a hematomas ndi mikwingwirima, kupezeka kwa magazi mu ndowe, komanso zovuta zina zoletsa magazi osiyanasiyana. Thrombocytopenia akuti ndi pomwe kuchuluka kwa maplateli kumatsikira m'munsi mwa malire a gawo la magawo 150,000 mpaka 450,000 pa lita imodzi yamwazi. Pankhaniyi, thandizo lachipatala loyenerera likufunika, apo ayi vutolo limatha kukhala ndi zotsatirapo zoyipa kwambiri.

Pali zifukwa zingapo zomwe zimapangitsa kuti magazi amwazi m'magazi a munthu alowe kwambiri.

• Matenda a oncological (makamaka khansa ya m'mafupa, khansa ya magazi ndi dongosolo la mitsempha),
• matenda a autoimmune
• matenda a impso
• uchidakwa
• zotsatira za chemotherapy
• kuperewera kwa folic acid kuchepa magazi kapena vitamini B12,
• kumwa mankhwala ena
• matenda a virus.

Wodwala akapezeka kuti ali ndi magazi ochepa m'magazi, chithandizo chamankhwala chimayamba.

Mutha kukulitsa kuchuluka kwa maselo amenewa pakusintha zakudya ndi moyo, komanso kugwiritsa ntchito mankhwalawa.

Chithandizo chogwira mtima kwambiri chomwe chimathandizira kuchulukitsa kwa magazi ndi Sodecor.

Kufotokozera, mawonekedwe ndi mphamvu ya mankhwalawa

Khalani omasuka kufunsa mafunso anu kwa wazachipatala wa nthawi zonse mwachindunji patsamba lino. Tikuyankha motsimikiza: Funsani funso >>

Sodecor ndi madzi akumwa amowa omwe amapangidwa pamaziko a mbewu.

Mankhwala ali ndi tonic komanso obwezeretsa, komanso kutchulidwa odana ndi kutupa komanso radioprotective.

Sodecor ikuphatikiza:

• zipatso zam'madzi am'madzi, zomwe zimakhala ndi zophera tizilombo toyambitsa matenda,
• dandelion muzu, wotchuka ndi choleretic, sedative, kugaya chakudya,
• zipatso za coriander, zomwe zimaphatikizapo zinthu zambiri zothandiza thupi zomwe zimakhala ndi zotsatira zabwino pa chiwindi,
• paini nati, kulimbikitsa chitetezo cha m'thupi ndi kutenga kagayidwe.
• sinamoni bark - antiseptic wachilengedwe,
• zipatso za cardamom zomwe zimakhala ndi antiseptic, carmative and anti-yotupa,
• ma cloves omwe ali ndi analgesic, antimicrobial and antiparasitic katundu,
• elecampane
• ginger
• licorice muzu.

Kuphatikiza pazomera, kukonzekera kumakhala ndi mowa wa ethyl ndi madzi osungunuka.

Sodecor ndi madzi ofiira ofiira okhala ndi fungo labwino. Chogulitsachi chimagulitsidwa m'mabotolo opangidwa ndi galasi lakuda ndi voliyumu ya 30, 50, 100 ml. Bokosi lirilonse limayikidwa m'bokosi lamatoni, lomwe lili ndi malangizo ogwiritsira ntchito mankhwalawa.

Momwe mungatenge Sodecor

Kweza milingo yamapulateni m'magazi, mankhwalawa amatengedwa madontho 15-35, atatha kuwapaka m'magalasi amadzimadzi (madzi ofunda, tiyi).

Kuti muchite bwino, mankhwalawa ayenera kugwedezeka osagwiritsidwa ntchito. Pafupipafupi makonzedwe ndi nthawi ya chithandizo amapatsidwa aliyense payekha kwa wodwala aliyense, kutengera ndi kuchuluka kwa ma protein am'magazi. Ngati palibe malingaliro a dotolo wina, ndiye kuti mankhwalawo amatengedwa maola 8 aliwonse kwa milungu iwiri.

Ndemanga za mankhwala

Malinga ndi kuwunika kwa anthu, kusintha kwamphamvu mu thrombocytopenia kumawonedwa kale masiku 3-4 atatenga Sodecor.

Zachidziwikire, sizotheka nthawi zonse kubwezeretsa zomwe zili mumwazi m'magazi mwa kungomwa mankhwalawo, chifukwa ndikofunikira kuthetseratu chomwe chimayambitsa chitukuko cha matenda. Komabe, phukusi la njira zochizira matendawa, Sodecor, m'maganizo a odwala ndi madotolo ambiri, amatenga gawo lomwe silingachitike.

Pa intaneti, mutha kupeza ndemanga zochepa za mankhwalawa. Ogwiritsa ntchito ena sanazindikire kuchuluka kwa mankhwalawa omwe amawonjezera kuchuluka kwa magazi m'magazi, koma adazindikira kuti Sodecor imabwezeretsa thupi lonse.

Kupezeka kwa mankhwala

Sodecor ikhoza kugulidwa ku malo ogulitsa mankhwala popanda mankhwala kuchokera kwa katswiri. Mtengo wapakati pa botolo wokhala ndi elixir umachokera ku ma ruble 110-250.

Potengera kapangidwe kake, Sodecor alibe mawonekedwe ndipo ndi mankhwala apadera.

Ndikofunika kukumbukira kuti kudzichitira wekhawekha kwa zinthu zomwe kuchepa kwa ziwalo zam'magazi kumakhala kosavomerezeka. Kuchita bwino kwa mankhwalawa kumalumikizidwa ndi mtundu wa matenda komanso njira yoyenera yosankhira njira zamankhwala. Kuti mupewe zovuta zilizonse zomwe zimayambitsidwa ndi thrombocytopenia, ndikofunikira kuperekera chithandizo kwa dokotala wodziwa ntchito.