Glucobay - mankhwala antidiabetes

Glucobai (mawu ofanana ndi mankhwalawa - Acarbose) ndiye mankhwala okhawo a antiidiabetes omwe amasonyezedwa amitundu 1 ndi 2 shuga. Chifukwa chiani sichinapeze kuti anthu ambiri amagwiritsa ntchito, mwachitsanzo, Metformin, ndipo chifukwa chiyani mankhwalawa ndi okongola kwambiri kwa anthu athanzi, kuphatikiza othamanga?

Monga Metformin, Glucobai ikadakhala yolondola kuyitanitsa osati othandizira a hypoglycemic, koma antihyperglycemic, chifukwa chimaletsa kukwera msanga kwa shuga poyankha ma carbohydrate ovuta, koma samayang'anira glycemia. Mtundu wachiwiri wa matenda ashuga, umagwiritsidwa ntchito nthawi zambiri, ndikuchita bwino kwambiri, umagwira ntchito limodzi ndi ena othandizira a hypoglycemic.

Glucobay exposition

Acarbose ndi cholepheretsa ma amylases - gulu la ma enzyme omwe amachititsa kuti maselo azikhala ndi zovuta kusintha, chifukwa thupi lathu limatha kuyamwa monosaccharides (glucose, fructose, sucrose). Njirayi imayamba mkamwa (imakhala ndi ma amylase ake), koma njira yayikulu imapezeka m'matumbo.

Glucobai, kulowa m'matumbo, imalepheretsa kuphatika kwa mafuta ochulukitsa am'molekyulu, kotero mafuta omwe amalowa mthupi ndi chakudya sangathe kumizidwa kwathunthu.

Mankhwalawa amagwira ntchito kwanuko, makamaka m'matumbo a lumen. Simalowa m'magazi ndipo sizikhudza ntchito ya ziwalo ndi machitidwe (kuphatikiza kupanga insulin, kupanga shuga m'magazi).

Mankhwala ndi oligosaccharide - nayonso mphamvu mankhwala aorganorganism Actinoplanes utahensis. Ntchito zake zimaphatikizapo kutsekereza cy-glucosidase, enzyme ya pancreatic yomwe imagwetsa zovuta zam'mimba kukhala mamolekyulu osavuta. Mwa kuletsa kuyamwa kwa zovuta zamankhwala, Acarbose amathandizira kuthetsa shuga wambiri ndikupangitsa matenda a glycemia kuchepa.

Popeza mankhwalawa amachepetsa kuyamwa, amangogwira ntchito mukatha kudya.

Ndipo popeza sizikulimbikitsa maselo a "responsible-cell" omwe amapanga ndi kubisala kwa insulin ya amkati, Glucobai siyonso imayambitsa matenda a glycemic.

Yemwe amawonetsedwa ngati mankhwalawo

Kuchepetsa kwa shuga kwa mankhwalawa sikunatchulidwe monga kwa hypoglycemic analogues, chifukwa chake, sizothandiza kugwiritsa ntchito mankhwalawa ngati monotherapy. Nthawi zambiri imafotokozedwa ngati chothandiza, osati pa mitundu yonse ya matenda a shuga okha, komanso pamikhalidwe ya prediabetes: kusala kwa vuto la glycemia, kusintha kwa kulolerana kwa shuga.

Momwe mungamwere mankhwala

Mu pharmac unyolo Acarbose, mutha kupeza mitundu iwiri: ndi mlingo wa 50 ndi 100 mg. Mlingo woyambira wa Glucobay, mogwirizana ndi malangizo ogwiritsira ntchito, 50 mg / tsiku. Sabata lililonse, posakwanira, mutha kutumiza mapiritsi a kuchuluka kwa 50 mg, ndikugawa mapiritsi onse muyezo waukulu. Ngati mankhwalawa amalekeredwa bwino ndi odwala matenda ashuga (ndipo pali zovuta zokwanira zosayembekezereka), ndiye kuti mankhwalawa amatha kusintha mpaka 3 r. / Tsiku. 100 mg aliyense. Muyezo wapamwamba kwambiri wa Glucobay ndi 300 mg / tsiku.

Amamwa mankhwalawo asanadye kapena ali mkati mwake, akumwa piritsi lonse ndi madzi. Nthawi zina madokotala amalangiza kutafuna mapiritsi ndi supuni yoyamba ya chakudya.

Ntchito yayikulu ndikupereka mankhwalawa mukuwunikira m'matumbo ang'onoang'ono, kotero kuti pofika nthawi yodya mafuta, anali wokonzeka kugwira nawo ntchito.

Ngati menyu mukadakhala kuti mulibe zakudya zamafuta (mazira, tchizi tchizi, nsomba, nyama yopanda buledi ndi mbale zokhala ndi wowuma), mutha kudumpha ndikumwa mapiritsi. Acarbose sagwira ntchito pankhani yogwiritsira ntchito monosaccharides yosavuta - shuga wowona, fructose.

Ndikofunika kuti musaiwale kuti chithandizo cha mankhwala a acarbose, monga mankhwala ena aliwonse osokoneza bongo, sichilowa m'malo mwa chakudya chamagulu ochepa, kuchita masewera olimbitsa thupi mokwanira, kuwongolera zakukhosi, kutsatira kugona ndi kupuma. Mankhwalawa ayenera kuthandizidwa tsiku lililonse mpaka atakhala njira yatsopano.

Mphamvu ya antihyperglycemic ya Glucobay imakhala yofooka, kotero nthawi zambiri imayikidwa ngati chida chowonjezera pakugwiritsira ntchito zovuta mankhwala. Monga tanena kale, mankhwalawo pawokha samayambitsa hypoglycemia, koma mu zovuta zovuta pamankhwala ena a hypoglycemic, zotere zimatheka. Amaletsa kuukiridwa osati ndi shuga, monga zimakhalira nthawi zina, - wozunzidwayo amayenera kupatsidwa chakudya chochepa cham'mimba, chomwe ma acarbose amakumana.

Zotsatira zoyipa

Popeza acarbose imalepheretsa kuyamwa kwa chakudya cham'madzi, chomaliza chimadziunjikira m'matumbo ndikuyamba kupatsa mphamvu. Zizindikiro za kupsya mtima zimawoneka mu mawonekedwe akukulira kwa kupanga kwa gasi, kugwedezeka, kuyimba muluzi, kumatulutsa, kupweteka m'derali, kutsegula m'mimba. Zotsatira zake, wodwala matendawa amaopa ngakhale kutuluka mnyumbamo, chifukwa vuto losalamulirika limasokoneza chikhalidwe.

Kusavutikako kumakulirakudya pambuyo pakupeza zakudya zamafuta ochulukirapo, makamaka mashuga, m'matumbo am'mimba ndipo amachepetsa ngati chakudya chamafuta pang'ono. Glucobai imagwira ntchito ngati mtundu wa mafuta ochulukirapo, ikukhazikitsa malire ake pazopezeka zamtunduwu. Zomwe gawo lililonse limachita palokha, sipangakhale kusinthika kokwanira m'mimba ngati mungayang'anire zakudya zanu komanso kunenepa.

Akatswiri ena amayerekezera makina ochita Glucobay ndi chithandizo cha kudwala kosalekeza: ngati wodwalayo ayesa kubwerera ku zizolowezi zake zoyipa, izi zimabweretsa zisonyezo zakupweteka kwambiri kwa thupi.

Kuphatikiza pa α-glucosidase, mankhwalawa amalepheretsa kugwira ntchito kwa lactase, enzyme yomwe imaphwanya shuga ya mkaka ndi 10%. Ngati munthu wodwala matenda ashuga ataona kale kuchepa kwa ntchito ya enzyme, tsankho la mkaka (makamaka mkaka ndi mkaka) zimathandizira izi. Zinthu zamkaka nthawi zambiri zimakhala zosavuta kugaya.

Nthawi zambiri vuto la kusowa kwa magazi ndilomwe thupi limachita ndipo khungu limatupa.

Monga mankhwala opangira ambiri, imatha kukhala totupa pakhungu, kuyabwa, redness, nthawi zina - ngakhale edema ya Quincke.

Contraindication ndi analogues a acarbose

Osakulemberani Glucobai:

Odwala odwala matenda amitsempha
Ndi zilonda zam'mimba,
Panthawi yotupa kwamatumbo (mu mawonekedwe owopsa kapena aakulu),
Anthu odwala matenda ashuga ndi hernia (inguinal, femal, umbilical, epigastric),
Amayi oyembekezera komanso oyembekezera
Ndi malabsorption syndrome,
odwala matenda a impso.

Pali ma fanizo ochepa a Glucobay: malinga ndi gawo lomwe limagwira (acarbose), lingasinthidwe ndi Alumina, komanso ndi chithandizo chamankhwala - ndi Vox.

Glucobay yochepetsa thupi

Ambiri mwa anthu padziko lapansi sakusangalala ndi kulemera kwawo komanso kuchuluka kwawo. Kodi ndizotheka kuletsa mayamwidwe am'madzi muopanda matenda ashuga ngati ndachimwa ndikudya? Omanga thupi amalangizidwa kuti "achotse keke kapena kumwa piritsi la Glucobay." Imalepheretsa ma pancreatic amylases, gulu la ma enzyme omwe amawononga ma polysaccharides kukhala ma analogi a mono. Chilichonse chomwe matumbo sanamwe, amadzipangira okha madzi, ndikuwotchera m'mimba.

Ndipo malingaliro ofunikira: ngati simungathe kudzikonzera nokha maswiti ndi makeke, idyani mapiritsi amodzi kapena awiri a Acarbose (50-100 mg) musanamwe mlingo wotsatira wa chakudya. Ngati mukuwona kuti mukudya kwambiri, mutha kumeza piritsi lina la 50 mg. Kutsegula m'mimba ndi mazunzo a "zakudya" zotere, koma sikuwongolera monga kutaya thupi, mwachitsanzo, ndi orlistat.

Ndiye kodi ndichabwino "kuzolowera chemistry" ngati mutha kuyambiranso zakudya zopanda pake pambuyo pa phwando lokondwerera? Gala Ref Refx idzapangidwa pakatha mwezi umodzi, ndipo mudzawongolera mwayi uliwonse, ngakhale wopanda madzi ndi zala ziwiri. Ndikosavuta komanso okwera mtengo kuthana ndi matendawa, chifukwa chake ndikosavuta kugwiritsa ntchito matumbo kuti muchepetse thupi. Carbose imapezeka, imakhala ndi zotsatira zoyipa zochepa, komanso imathandizira kuwongolera chakudya.

Glucobay - ndemanga za anthu odwala matenda ashuga

Anton Lazarenko, Sochi "Ndani amasamala, ndikupereka lipoti la miyezi iwiri ya ascarbose. Kuyambira ndi 50 mg / osachepera nthawi, pang'onopang'ono adakwera mpaka 100 mg / panthawi, monga momwe adalangidwira. Kuphatikiza apo, nthawi ya nkhomaliro, ndimapabe piritsi la Novonorm (4 mg). Seti yotere imandilola kuti ndizitha kuwongolera ngakhale masana masana: maola awiri nditatha chakudya chokwanira (malinga ndi zomwe anthu odwala matenda ashuga) amapanga pa glucometer - osaposa 7 ndi theka mmol / l. M'mbuyomu, panthawiyo panali ochepera 10 panthawiyo. "

Vitaliy Alekseevich, dera la Bryansk “Matenda anga a shuga ndi okalamba. Kuti shuga m'mawa zinali zabwinobwino, ndimamwa kuyambira madzulo Glyukofazh Long (1500 ml), ndipo m'mawa - kupita ku Trazhent (4 mg). Asanadye, ndimamwa piritsi la Novonorm nthawi zonse, koma silikhala ndi shuga. Adawonjezeranso 100 mg ya Glucobai pachakudya chamasana, popeza zolakwika zomwe zidapezeka pakadali pano ndizambiri (beets, kaloti, mbatata). Glycated hemoglobin tsopano ndi 5.6 mmol / L. Ngakhale atalemba chiyani, mankhwalawo ali ndi mndandanda wa mankhwala othandizira odwala matenda ashuga, ndipo simuyenera kuwachotsa pa alumali apamwamba. ”

Irina, Moscow "Mtengo wa Glyukobay ndi ma ruble 670-800; matenda a shuga sangandichiritse, koma atha kuwononga. Ndimagwiritsa ntchito ngati chida chimodzi ngati pangafunikire kulipira chakudya chamoto munthawi yachilendo (pamsewu, paphwando, paphwando labungwe). Koma kwakukulu, ndimadutsa ndi Teva Metformin ndikuyesera kusunga zakudya. Glucobai ndi Metformin, zoona, sizingafanane, koma ndikuganiza kuti kuthekera kwake monga wotseka nthawi imodzi ndikulimbikira kuposa Metformin Teva. "

Ndiye kodi ndiyofunika kapena siyabwino kumwa Glucobai? Tiyeni tiyambe ndi zabwino zopanda malire:

Mankhwalawa samamwetsedwa m'magazi ndipo alibe mphamvu m'thupi.
Simalimbikitsa kaphatikizidwe ndi insulin yakeyo, motero palibe hypoglycemia pazotsatira zoyipa.
Kukhazikika kwadziwika kuti kugwiritsa ntchito acarbose nthawi yayitali kumachepetsa cholesterol "yoyipa" komanso kuchuluka kwa atherosulinosis wodwala matenda ashuga,
Kuletsa kuyamwa kwa mafuta kumathandiza kuti muchepetse kunenepa.

Pali zovuta zochepa: kugwira ntchito molakwika ndi kusayenerera kwa monotherapy, komanso kutchulidwa koyipa mwanjira yamavuto a dyspeptic, omwe amathandizira kuchepetsa kunenepa ndi kudya.

Glucobay: malangizo ogwiritsira ntchito, mtengo, ndemanga, analogi

Matenda a shuga ndi njira yodziwika bwino ya endocrinological. Matendawa ndi amitundu iwiri - amadalira insulin komanso osadalira insulini. Matenda a shuga ndi matenda osachiritsika.

Pochiza matenda, mankhwalawa amagwiritsidwa ntchito omwe amathandizira kukula kwa shuga. Glucobai 100 mg imadziwika kuti ndi imodzi mwazamankhwala odziwika kwambiri amtunduwu. Mankhwalawa amagwiritsidwa ntchito pothandizidwa ndi matenda a shuga 1 komanso mankhwalawa amamuuza kuti adwala matendawa.

Mankhwala amapangidwa ngati mapiritsi. Glucobai 50 mg ndi 100 mg akugulitsidwa. Amasiyana pakati pawo pa kuchuluka kwa zinthu zomwe zimagwira piritsi limodzi. Mtengo wa mankhwalawa ndi ma ruble 660-800. Pogula mankhwala, muyenera kupereka mankhwala oyenera kuchokera kwa dokotala.

Glucobai ndi othandizira a hypoglycemic pakugwiritsa ntchito pakamwa. Yogwira pophika mankhwala ndi acarbose. Izi zimakhazikika pamlingo wa glucose m'magazi.

Kodi mankhwalawa amagwira ntchito bwanji? Acarbose ndi chinthu chomwe chimalepheretsa matumbo alpha glucosidase. Yogwira pophika mankhwala amachepetsa kusintha kwa enzymatic kwa ma disaccharides, oligosaccharides ndi polysaccharides kukhala monosaccharides. Chifukwa cha izi, kuchuluka kwa mayamwidwe m'matumbo amachepa.

Ndizofunikira kudziwa kuti kugwiritsa ntchito mapiritsi, hypoglycemia yayikulu sikupita patsogolo. Kugwiritsa ntchito mankhwala pafupipafupi kumachepetsa chiopsezo:

Myocardial infaration.
Kuukira kwa hypoglycemia ndi hyperglycemia.
Kukula kwa matenda opatsirana a mtima.

Pazitali kwambiri pazogwira ntchito m'magazi zimawonedwa pambuyo pa maola 1-2. Zosagwira metabolites za mankhwalawa zimapukusidwa m'matumbo, impso ndi chiwindi.

Mukasankha Glucobai, malangizo ogwiritsira ntchito akuyenera kuphunzira, chifukwa ili ndi chidziwitso chonse, zisonyezo, zotsutsana ndi zoyipa. Kodi ndikofunika kumwa mankhwalawa munthawi iti?

Malangizowo akuti mankhwalawa amayenera kugwiritsidwa ntchito pa zovuta za matenda a shuga 1. Chizindikiro chogwiritsidwira ntchito ndi mtundu wa 2 shuga. Mutha kugwiritsa ntchito mankhwalawa kunenepa kwambiri komanso matenda a shuga.

Koma kuchepa thupi mothandizidwa ndi Glucobay ndizotheka pokhapokha mutatsatira zakudya zapadera. Ndikofunika kudziwa kuti munthu wonenepa ayenera kudya pafupifupi kilomita 1000 patsiku. Kupanda kutero, hypoglycemia ikhoza kukhala, mpaka kuukira kwa hypoglycemic.

Momwe mungamwe mankhwalawo? Imwani mapiritsi musanadye. Mlingo woyambirira ndi 150 mg. Gawani tsiku lililonse mu 3 waukulu. Ngati ndi kotheka, mlingo umakwezedwa ku 600 mg. Koma mu nkhani iyi, tsiku ndi tsiku mlingo uyenera kugawidwa mu 3-4 Mlingo.

Ngati munthawi ya chithandizo, wodwalayo amakhala ndi vuto lotsekula m'mimba, ndiye kuti mlingo wake uyenera kuchepetsedwa, kapena mankhwalawo amayenera kusokonezedwa palimodzi. Kutalika kwa chithandizo ndi Glucobaem amasankhidwa payekhapayekha.

Contraindication kumwa mapiritsi:

Ziwengo magawo a mankhwala.
Zaka za ana. Mankhwalawa sanalembedwe kwa odwala azaka zosakwana 18.
Kukhalapo kwa matenda owopsa kapena matumbo. Ndemanga za madokotala zikuwonetsa kuti mankhwalawa ndiwowopsa kupereka kwa anthu omwe ali ndi vuto la matumbo.
Matenda a shuga ketoacidosis.
Kuphwanya chiwindi. Ndi zoletsedwa kugwiritsa ntchito mankhwalawa ngati munthu akudwala chiwindi, matenda a chiwindi kapena chiwindi.
Zilonda zam'mimba kapena ziwalo zina zam'mimba thirakiti.
Nthawi yapakati.
Nthawi yonyamula. Koma malangizowo akuti mankhwalawa amatha kuikidwa kuti akachulukitse azimayi pokhapokha kuyimitsidwa kwakanthawi kwa bere.
Kulephera kwamkati (ndi zomwe zili ndi creatinine pamtunda 2 ml pa 1 dl).
A Remgeld's syndrome.
Kukhalapo kwa hernias yayikulu mkati mwa khoma lam'mimba.
Malabsorption syndrome kapena maldigestion.

Mosamala, mankhwalawa amaperekedwa kwa anthu atachitidwa opaleshoni. Komanso kusintha mtundu wa mankhwalawo kungakhale kofunikira ngati munthu akudwala matenda opatsirana kapena kutentha thupi. Ndikofunika kudziwa kuti mukamalandira chithandizo, mankhwala omwe amakhala ndi sucrose yambiri sangathe kudya. Kupanda kutero, zizindikiro za dyspeptic zimayamba.

Kodi Glucobai amalumikizana bwanji ndi mankhwala ena? Zinapezeka kuti mankhwalawa sagwira ntchito bwino ngati matumbo amatenga, ma antacid, kapena kukonzekera kwa enzyme. Tiyeneranso kudziwa kuti kugwiritsa ntchito Glucobay munthawi yomweyo pogwiritsa ntchito mankhwala a sulfonylurea kapena insulin, mphamvu ya hypoglycemic imatheka.

Ndikulimbikitsidwa kwambiri kuti musagwiritse ntchito chida ichi limodzi ndi thiazide diuretics, kulera kwamlomo, corticosteroids, nicotinic acid. Ndi kulumikizana kwawo, kuwonongeka kwa matenda ashuga kumatha. Komanso, matenda amtunduwu amatha kupanga ngati mutatenga phenothiazines, estrogens, isoniazid, calcium blockers, adrenomimetics nthawi yomweyo monga Glucobai.

Mukamagwiritsa ntchito mapiritsi a Glucobai, pali kuthekera kwa mawonekedwe a zotsatirapo zake:

Kuchokera pamimba yokhudza chakudya: kupweteka kwa epigastric, nseru, kutsegula m'mimba, kusisita. Ngati bongo, pali mwayi wa kuchuluka asymptomatic mu ntchito ya chiwindi michere. Milandu imadziwikanso pamene kutsekeka m'matumbo, jaundice ndi hepatitis amapezeka panthawi ya chithandizo.
Thupi lawo siligwirizana.
Kutupa.

Pankhani ya bongo, anaphylactic zimachitika. Pankhaniyi, chithandizo chamankhwala chimachitika.

Ngati Glucobay adatsutsana pazifukwa zilizonse, ndiye kuti wodwalayo adapatsidwa gulu lake. Mosakayikira, njira yabwino kwambiri pa chida ichi ndi Glucofage. Mankhwalawa amagwiritsidwanso ntchito pochiza matenda a shuga amtundu 1 komanso 2. Mtengo wa mankhwalawo m'mafakisi ndi 500-700 rubles.

Anthu ambiri ali ndi chidwi ndichomwe pali kusiyana pakati pa Glucofage ndi Glucobay. Kusiyana kwakukulu pakati pa mankhwalawa ndi kapangidwe ndi mfundo zoyenera kuchitapo. Koma onsewa amagwiranso ntchito.

Kodi glucophage imagwira ntchito bwanji? Gawo lomwe limagwiritsa ntchito mankhwalawo limatchedwa metformin. Katunduyu ali ndi tanthauzo la hypoglycemic. Ndikofunikira kudziwa kuti odwala omwe ali ndi shuga omwe ali ndi shuga, metformin ilibe mphamvu.

Mphamvu yamachitidwe a Glucofage imakhazikitsidwa ndi kuthekera kwa chinthu chake yogwira ntchito kuti chiwonjezere mphamvu ya maselo kulowetsedwa ndikuchepetsa kuchuluka kwa mayamwidwe a glucose m'mimba. Chifukwa chake, mankhwalawa amathandizira:

Anachepetsa kapangidwe ka shuga m'chiwindi.
Kukondoweza kwa kugwiritsidwa ntchito kwa glucose mu minofu minofu.
Sinthani kagayidwe ka lipid.
Cholesterol otsika, triglycerides ndi lipoproteins, omwe amakhala ndi otsika kwambiri.

Glucophage imatha kusiyanitsidwa ndi kuthekera kwake kuchokera ku mankhwala ena a hypoglycemic. Izi ndichifukwa choti mankhwalawa ali ndi zizindikiro zambiri za bioavailability. Amapanga pafupifupi 50-60%. Pazitali kwambiri pazogwira zinthu zomwe zimapezeka m'magazi zimawonedwa pambuyo pa maola 2,5.

Momwe mungamwe mankhwalawo? Muyenera kumwa mapiritsi pakudya kapena musanadye. Mlingo wa tsiku ndi tsiku nthawi zambiri amakhala magalamu awiri a 2-3 (2000-3000 mamililita). Ngati ndi kotheka, pakatha masiku 10-15, mlingo umakulitsidwa kapena kuchepa. Mlingo wokonza ndi 1-2 magalamu. Ndikofunika kudziwa kuti mlingo wa tsiku ndi tsiku umasiyana. Munjira zambiri, zimatsimikiziridwa ndi mlingo wa insulin.

Mankhwala oletsedwa ndi:

Matupi a ziwalo zamagulu a glucophage.
Kulephera kwina.
Kuphwanya chiwindi.
Kuthetsa madzi m'thupi.
Kulephera kopindulitsa.
Matenda opatsirana.
Lactic acidosis.
Matenda a shuga.
Acute myocardial infarction (mbiri).
Zakudya za Hypocaloric (zosakwana ma kilocalories 1000 patsiku).
Mimba komanso kuyamwa.

Mukamagwiritsa ntchito mankhwalawa, kusokonezeka kwa ntchito m'mimba, CCC ndi dongosolo lopangira magazi limatha kukhazikika. Palinso kuthekera kwa vuto la metabolic. Nthawi zambiri, mavuto amayamba ndi mankhwala osokoneza bongo.

Kanemayo munkhaniyi akukamba za zabwino komanso zoipa za mankhwala a Glucobay.

Glucobay - Hypoglycemic mankhwala. Acarbose ndi pseudotetrasaccharide wa tizilombo tating'onoting'ono. Limagwirira a zochita za acarbose zachokera kulepheretsa kwamatumbo enzyme alpha-glucosidase, amene amawononga di-, oligo- ndi polysaccharides. Chifukwa cha kuponderezana kwa ntchito ya enzyme, kuchuluka kotenga mphamvu kwa nthawi yochulukirapo kwa mafuta kumachitika, ndipo, chifukwa chake, shuga, yemwe amapangika pamene zakudya zamafuta zimaphwanyidwa. Chifukwa chake, acarbose imachepetsa kuyenda kwa glucose kulowa m'magazi ndikuchepetsa kuchuluka kwa shuga m'magazi mukatha kudya. Pogwiritsa ntchito kuyamwa kwa shuga m'matumbo, mankhwalawa amachepetsa kusinthasintha kwake m'magazi am'magazi ndipo zimayambitsa kutsika kwake.

Pankhani yakuwonjezeka kwa ndende ya glycated hemoglobin, acarbose imachepetsa mulingo wake.

Mu kafukufuku woyembekezeka, wosasankhidwa, wolamulidwa ndi placebo, wofufuza mosatulutsa nthawi yayitali zaka 3-5, zaka pafupifupi 3.3), zomwe zimakhudza odwala 1,429 omwe ali ndi vuto logometsa shuga, chiwopsezo chokhala ndi matenda a shuga a 2 pagulu lachipatala cha Glucobay chatsika ndi 25 %

Odwala awa adawonetsanso kuchepa kwakukulu kwa pafupipafupi pa zochitika zamtima zonse ndi 49%, komanso myocardial infarction (MI) - mwa 91%. Zotsatira izi zidatsimikiziridwa ndi kusanthula kwa meta kwa maphunziro 7 olamulidwa ndi placebo pochiza matenda a shuga 2 a mellitus (2180 odwala onse, omwe 1248 adalandira acarbose ndipo 932 adalandira placebo). Odwala omwe amalandila acarbose, ndipo mwa omwe mtundu wa shuga wachiwiri umapangidwa kwa nthawi yoyamba, chiopsezo chotenga MI chinachepa ndi 68%.

Pansipa aperekedwa Glucobay analogues, mankhwala ofanana akuwonetsa kuti agwiritse ntchito komanso momwe amagwirira ntchito, komanso mitengo komanso kupezeka kwa ma analogues pama pharmacies. Poyerekeza ndi analogues, phunzirani mosamala zosakaniza zomwe zimagwiritsidwa ntchito ndi mankhwalawo, monga lamulo, mtengo wa mankhwala okwera mtengo uli ndi bajeti yake yotsatsa komanso zowonjezera zomwe zimawonjezera mphamvu ya chinthu chachikulu. Malangizo a Glucobay ogwiritsira ntchito
Tikukupemphani kuti musankhe nokha kuti mulowe m'malo mwa Glucobay nokha, malinga ndi momwe akuwongolera komanso chilolezo cha dokotala.

Florateka Diabenol amalimbikitsa odwala matenda a shuga omwe amadalira insulin:
- imawonjezera ntchito ya masisamba a ma cell a beta ya Langerans beta
- samabwezeretsa insulin modalirika, koma imagwiranso ntchito njira ya metabolic, imalepheretsa kuperewera kwa dongosolo la endocrine ku chithokomiro cha chithokomiro, mazira, njira za metabolic, mtima ndi kugaya chakudya
- amalepheretsa kuti thupi lizifa chifukwa chakuwonjezereka kwa mafuta ndi mapuloteni, kuledzera kwa thupi
- amatsuka magazi ndi zamitsempha
- Amalepheretsa zovuta: chikomokere, kusokonezeka kwamitsempha yamagazi, kuphwanya kwamkati, kuwonongeka kwamitsempha, chitetezo chokwanira, ntchito ya kwamikodzo, matenda amisempha

Mankhwala Florateka Diabenol Chimalimbikitsidwa pa matenda a shuga a 2:
- kumawonjezera kukhudzika kwa minofu
- amateteza kagayidwe kazakudya
- Amachepetsa kapangidwe ka shuga ndi chiwindi
- amalepheretsa matenda amtundu wa endocrine, njira yobereka, impso, mtima, matenda a metabolic
- amatsuka magazi ndi zamitsempha
Mankhwala amatha kusintha shuga m'magazi ndipo amalimbitsa thupi
Makapisozi amalimbikitsidwa chifukwa cha kuchuluka kwa shuga m'magazi, kuphwanya gawo la kapamba, matenda ashuga omwe amayamba ndi mankhwala, matenda, ndi hyperglycemia pa nthawi yapakati.

Chitosanovit Ndikulimbikitsidwa kuti mugwiritse ntchito mitundu yonse ya matenda ashuga monga gawo la mankhwala osokoneza bongo, komanso kwa anthu omwe amamwa kwambiri shuga, ufa kapena zakudya zama carb zambiri (anthu omwe ali ndi ntchito yayikulu) monga prophylactic yachilengedwe yomwe imathandizira ntchito zapancon.

Kuperewera kwa insulin m'thupi kumabweretsa kusokonezeka kwa dongosolo la endocrine komanso kukula kwa matenda ashuga ndi hypoglycemia. Kusungitsa kuchuluka kwa glucose m'magazi, odwala amapatsidwa mankhwala, omwe akuphatikizapo Glucobay.

Mankhwalawa amagwiritsidwa ntchito ngati gawo la chithandizo chovuta cha matenda ashuga. Musanagwiritse ntchito mankhwalawa, wodwalayo amalimbikitsidwa kuti adziwe mayeso angapo azachipatala kuti apewe kupezeka kwa zotsutsana ndikupewera kuwoneka.

Kusungitsa kuchuluka kwa glucose m'magazi, odwala amapatsidwa mankhwala, omwe akuphatikizapo Glucobay.

Mankhwalawa amapezeka piritsi la 50 ndi 100 mg. Mankhwala ndi maofesi azachipatala amaperekedwa m'mabokosi okhala ndi 30 kapena 120 mapiritsi.

Zogulitsa zimakhala ndi mtundu woyera kapena wachikasu.

Pali zoopsa ndi zolemba pamapiritsi: logo kampani yopanga mankhwala kumbali ina ya mankhwalawo ndi manambala a kipimo (G 50 kapena G 100) mbali inayo.

Glucobay (mu Chilatini) akuphatikiza:

yogwira pophika - acarbose,
Zowonjezera zina - MCC, wowuma chimanga, magnesium stearate, anhydrous colloidal silicon dioxide.

Mankhwala omwe amagwiritsidwa ntchito pakamwa ali m'gulu la othandizira a hypoglycemic.

Glucobay imaperekedwa ku malo ogulitsira mankhwala ndi malo azachipatala okhala ndi mapepala okhala ndi 30 kapena 120.

Kuphatikizidwa kwa mapiritsiwa kumaphatikizapo acarbose pseudotetrasaccharide, omwe amalepheretsa zochita za alpha-glucosidase (puloteni yamatumbo ang'onoang'ono yomwe imaphwanya di-, oligo- ndi polysaccharides).

Pambuyo poti zinthu zayamba kulowa mthupi, njira yolekeramo mafuta am'mimba imalephereka, glucose amalowa m'magazi m'magawo ang'onoang'ono, glycemia amakhala.

Chifukwa chake, mankhwalawa amalepheretsa kuchuluka kwa ma monosaccharides m'thupi, amachepetsa chiopsezo chokhala ndi matenda a shuga, matenda a mtima ndi matenda ena amthupi. Kuphatikiza apo, mankhwalawa amakhudza kuchepa thupi.

Muzochita zachipatala, nthawi zambiri mankhwalawa amakhala ngati othandizira. Mankhwalawa amagwiritsidwa ntchito popanga zovuta za matenda amitundu 1 komanso mtundu wachiwiri wa matenda ashuga komanso pochotsa matenda ashuga.

Zinthu zomwe zimapanga mapiritsiwo zimatengedwa pang'onopang'ono kuchokera m'mimba.

Zinthu zomwe zimapanga mapiritsi a Glucobai zimatengedwa pang'onopang'ono kuchokera m'mimba.

Cmax yothandizira yogwira m'magazi imawonedwa pambuyo pa maola 1-2 ndi pambuyo pa maola 16-24.

Mankhwalawa amapukusidwa, kenako ndikufotokozedwa ndi impso ndikugaya dongosolo la chakudya kwa maola 12-14.

Mankhwala amalembera:

Chithandizo cha matenda a shuga 1
Kuchotsa matenda asanafike matenda ashuga (kusintha kwa kulolera kwa glucose, kusokonekera kwa kudya kwa glycemia),
letsa kukula kwa matenda a shuga a mtundu 2 mwa anthu omwe ali ndi prediabetes.

Therapy imapereka njira yolumikizira. Pogwiritsa ntchito mankhwalawa, wodwalayo amakulimbikitsidwa kuti azitsatira zakudya zothandizira kuti azikhala ndi moyo wakhama (masewera olimbitsa thupi, kuyenda tsiku ndi tsiku).

Pogwiritsa ntchito mankhwala Glucobai, wodwalayo amakulimbikitsidwa kuti azitsatira zakudya zochizira.

Pali zotsutsana zingapo pakugwiritsa ntchito mapiritsi:

zaka zaana (mpaka zaka 18),
Hypersensitivity kapena kusalolera payekha pazigawo za mankhwala,
nthawi ya bere, kukomoka,
matenda aakulu a m'mimba, omwe amaphatikizidwa ndi kuphwanya chimbudzi ndi mayamwidwe,
matenda a chiwindi,
matenda ashuga ketoacodosis,
zilonda zam'mimba
matumbo stenosis,
hernias wamkulu
Matenda a Remheld
kulephera kwa aimpso.

Mankhwala ayenera kumwedwa mosamala ngati:

wodwalayo wavulala ndipo / kapena akuchitidwa opaleshoni,
wodwalayo apezeka ndi matenda opatsirana.

Pa chithandizo, ndikofunikira kuti muwonane ndi dokotala ndikupimidwa pafupipafupi, chifukwa zomwe zimapanga ma enzymes a chiwindi zimatha kuchuluka m'miyezi isanu ndi umodzi yoyambirira.

Asanadye, mankhwalawa amadya kwathunthu, kutsukidwa ndi madzi pang'ono. Pakati pa chakudya - mawonekedwe osweka, ndi gawo loyamba la mbale.

Mlingo wake umasankhidwa ndi katswiri wazachipatala kutengera mtundu wa thupi la wodwalayo.

Chithandizo chomwe amalimbikitsa odwala omwe ali ndi matenda ashuga ndi awa:

kumayambiriro kwa mankhwala - 50 mg katatu patsiku,
pafupifupi tsiku lililonse 100 mg katatu patsiku,
Mlingo wowonjezereka - 200 mg katatu pa tsiku.

Mlingo ukuwonjezeka pakalibe matenda masabata 4-8 pambuyo poyambira chithandizo.

Ngati, kutsatira zakudya ndi malingaliro a dokotala yemwe wakupezekapo, wodwalayo akuchulukitsa kapangidwe ka mpweya ndi kutsegula m'mimba, kuwonjezeka kwa mlingo sikuvomerezeka.

Asanadye, mankhwala a Glucobai amadyedwa kwathunthu, kutsukidwa ndi madzi pang'ono.

Pofuna kupewa matenda a shuga a 2, momwe mungagwiritsire ntchito mankhwalawa ndizosiyana pang'ono:

kumayambiriro kwa mankhwala - 50 mg 1 nthawi patsiku,
ambiri achire mlingo ndi 100 mg katatu patsiku.

Mlingo ukuwonjezeka pang'onopang'ono masiku 90.

Ngati menyu wodwala alibe zakudya, ndiye kuti mutha kudumpha kumwa mapiritsi. Pankhani ya kudya fructose ndi glucose wangwiro, mphamvu ya acrobase imachepetsedwa kukhala zero.

Odwala ena amagwiritsa ntchito mankhwalawa chifukwa cha kuwonda. Komabe, kugwiritsa ntchito mankhwala alionse kuyenera kuvomerezedwa ndi adokotala.

Kuchepetsa thupi, mapiritsi (50 mg) amatengedwa nthawi imodzi patsiku. Ngati munthu akulemera zopitilira 60 kg, mulingo wake umachulukitsidwa kawiri.

Odwala ena amagwiritsa ntchito mankhwala Glucobay kuti achepetse thupi.

Mankhwalawa, nthawi zina, odwala amakhala ndi mavuto:

kutsegula m'mimba
chisangalalo
kupweteka m'dera la epigastric,
nseru

Zina mwa zomwe zimayambitsa matendawa zimapezeka (kawirikawiri):

zidzolo pa khungu
exanthema
urticaria
Edincke's edema,
kusefukira kwa mitsempha ya magazi ya chiwalo kapena gawo limodzi la magazi ndi magazi.

Nthawi zina, kuchuluka kwa michere ya chiwindi kumawonjezera odwala, jaundice amawoneka, ndipo chiwindi chimayamba (kawirikawiri).

Kugwiritsa ntchito mankhwalawa sikukhudza luso loyendetsa magalimoto payokha. Komabe, mukamakumana ndi zotsatirapo zoyipa (nseru, kutsegula m'mimba, kupweteka) pakumwa mankhwalawa, muyenera kusiya kuyendetsa.

Malinga ndi malangizo ogwiritsira ntchito, osachepetsa kapena kukulitsa mulingo.

Kusintha kwa mankhwalawa sikofunikira.

Ndi contraindicated ngati wodwala wapezeka ndi aimpso kulephera.

Mukamagwiritsa ntchito Mlingo wambiri wa mankhwalawa, kutsekula m'mimba ndi kuphwanya kwamimba kumatha kuchitika, komanso kuchepa kwa ziwalo zam'magazi.

Nthawi zina, odwala amakhala ndi mseru komanso kutupa.

Mankhwala osokoneza bongo amatha kuchitika mukamagwiritsa ntchito mapiritsi limodzi ndi zakumwa kapena zinthu zomwe zimakhala ndi mafuta ambiri.

Kuti muchepetse zizindikiro izi kwakanthawi (maola 4-6), muyenera kukana kudya.

Mankhwala osokoneza bongo amatha kuchitika mukamagwiritsa ntchito mapiritsi limodzi ndi zakumwa kapena zinthu zomwe zimakhala ndi mafuta ambiri.

Hypoglycemic zotsatira za mankhwala zomwe zimafunsidwa zimapangidwira ndi insulin, metformin ndi sulfonylurea.

Kugwiritsa ntchito bwino kwa mankhwalawa kumachepetsedwa ndi kugwiritsa ntchito nthawi yomweyo ya acrobase ndi:

nicotinic acid ndi kulera kwamlomo,
estrogens
glucocorticosteroids,
mahomoni a chithokomiro
thiazide okodzeya,
phenytoin ndi phenothiazine.

Zakumwa zoledzeretsa zimawonjezera shuga m'magazi, kotero kumwa mowa panthawi ya mankhwala kumatsutsana.

Mwa mankhwala omwe ali ofanana mu zamankhwala, zotsatirazi zalembedwa:

Mapiritsi othandizira.

Pali milandu yogulitsa mankhwalawa popanda kulandira dokotala wovomerezeka. Komabe, kudzipereka nokha ndi chifukwa cha zovuta zosasintha.

Mtengo wamapiritsi (50 mg) umasiyanasiyana kuchokera ku 360 mpaka 600 ma ruble pazinthu 30 pa paketi iliyonse.

Pakati pa mankhwala ofanana mu pharmacological, Siofor amadziwika.

Mapiritsi amakulimbikitsidwa kuti asungidwe mu kabati kapena m'malo ena amdima, pamtunda wosaposa + 30 ° С.

Zaka 5 kuyambira tsiku lomasulidwa.

BAYER SCHERING PHARMA AG (Germany).

Mikhail, wazaka 42, Norilsk

Mankhwalawa ndi chida chothandiza pa zovuta kuchiritsa. Odwala onse ayenera kukumbukira kuti mankhwalawa samachepetsa kudya, kotero pakumwa mankhwalawa ndikofunikira kuti muchepetse kunenepa, kutsatira zakudya ndi masewera olimbitsa thupi.

Mankhwala ndi Glucobai, madokotala amalimbikitsa kuti azikhala ndi moyo wakhama (masewera olimbitsa thupi, kuyenda tsiku ndi tsiku).

Elena, wazaka 52, St. Petersburg

Ndili ndi matenda ashuga a 2, onenepa kwambiri. Malinga ndi endocrinologist, adayamba kumwa mankhwalawa malinga ndi chiwembu chowonjezeka, kuphatikiza ndi mankhwala othandizira.Pambuyo pa chithandizo cha miyezi iwiri, adachotsa makilogalamu owonjezera asanu, pomwe kuchuluka kwa shuga m'magazi kumachepera. Tsopano ndikupitilizabe kugwiritsa ntchito mankhwalawa.

Wachiroma, wazaka 40, Irkutsk

Ndikusiyirani ndemanga kwa iwo omwe amakayikira kuyamwa kwa mankhwalawa. Ndinayamba kumwa acrobase miyezi 3 yapitayo. Mlingo ukuwonjezeka pang'onopang'ono, malinga ndi malangizo. Tsopano ndimamwa 1 pc (100 mg) katatu patsiku, makamaka musanadye. Pamodzi ndi izi, ndimagwiritsa ntchito piritsi limodzi la Novonorm (4 mg) kamodzi patsiku. Njira yochizira iyi imakupatsani mwayi kuti muzidya mokwanira ndikuwongolera shuga. Kwa nthawi yayitali, zizindikiro pa chipangizocho sizidutsa 7.5 mmol / L.

Olga, wazaka 35, Kolomna

Mankhwalawa amagwiritsidwa ntchito pochiza matenda ashuga, koma osati kuchepetsa thupi. Ndikuwalangizani odwala kuti amwe mankhwalawo pokhapokha ngati adokotala adakupangitsani, ndipo kwa anthu athanzi ndibwino kusiya lingaliro lochepetsa thupi kudzera pa chemistry. Mnzanu (osati wodwala matenda ashuga) kuchokera pakulandila acrobase adawoneka wamphamvu kwambiri pamakono ndipo chimbudzi chidasweka.

Sergey, wazaka 38, Khimki

Mankhwalawa amalepheretsa kuyamwa kwa zopatsa mphamvu zomwe zimalowa m'thupi kudzera m'mankhwala osokoneza bongo, chifukwa chida chimathandiza kuchepetsa thupi. Mkazi wa miyezi 3 wogwiritsa ntchito acrobase adachotsa ma kilogalamu 15 owonjezera. Komabe, adasunga chakudyacho ndipo amangodya zakudya zabwino kwambiri komanso zatsopano. Sanakhale ndi zotsatila zake. Koma ngati mukukhulupirira ndemanga, kusapeza zakudya zoyenera mukamamwa mapiritsiwo kumakhudza phindu ndi kulolera kwa mankhwalawo.

Endocrine kusinthanitsa diagnostics, Mankhwala ndi maphunziro akuthupi - M., 2014. - 500 p.
Mpukutu, matenda a shuga a Elena. Timalimbana ndikupambana: monograph. / Elena Svitko. - M: Nyumba ya Strelbitsky Multimedia Publishing House, 2013. - 971 p.
Neumyvakin, I.P. Matenda a shuga / I.P. Neumyvakin. - M: Dilya, 2006 .-- 256 p.

Ndiloleni ndidziwitse. Dzina langa ndi Elena. Ndakhala ndikugwira ntchito ya endocrinologist kwa zaka zoposa 10. Ndikukhulupirira kuti pakadali pano ndili katswiri pantchito yanga ndipo ndikufuna kuthandiza alendo onse omwe amapezeka pamalowo kuti athetse zovuta osati ntchito. Zinthu zonse za tsambalo amazisonkhanitsa ndikuzikonza mosamala kuti athe kufotokoza zambiri zofunikira. Musanagwiritse ntchito zomwe zikufotokozedwa pa webusaitiyi, kufunsana ndi akatswiri ndizofunikira nthawi zonse.