Insulin Humalog

Insellitus yodalira matenda a shuga ndi matenda omwe amadziwika kuti amafunikira insulin. Insulin imalowetsedwa.

Mpaka pano, makampani opanga mankhwala amapanga ma insulin ambiri pokonzekera odwala matenda ashuga, omwe adapangira jakisoni. Mankhwalawa osiyanasiyana amatha kukhala ndi mayina osiyanasiyana, mtundu wake komanso mtengo wake. Chimodzi mwa izo ndi Humalog insulin.

Mankhwala

Humalog insulin ndi ma DNA omwe amafunikanso kuchuluka kwa ma cell a thupi la munthu. Kusiyana pakati pa Humalog ndi insulin yachilengedwe ndi njira yotsutsana ya amino acid pamalo a 29 ndi 28 a insulin B. Zotsatira zazikulu zomwe ali nazo ndi kuyendetsa kwa kagayidwe kazakudya

Humalog ilinso ndi anabolic. M'maselo am'misempha, kuchuluka kwa mafuta acids, glycogen ndi glycerol kumawonjezera, kupanga mapuloteni kumawonjezeka, kuchuluka kwa kugwiritsidwa ntchito kwa amino acid kumawonjezeka, koma kuchuluka kwa glycogenolysis, gluconeogeneis, ndi kutulutsidwa kwa ma amino acid kumachepa.

Mthupi la odwala omwe ali ndi matenda ashuga a mitundu yonse iwiri chifukwa chogwiritsidwa ntchito ndi Humalog, zovuta za hyperglycemia zomwe zimawonekera pambuyo chakudya zimachepetsedwa kwakukulu pokhudzana ndi kugwiritsidwa ntchito kwa insulin yaumunthu.

Kwa odwala omwe amalandira mtundu wa insulin nthawi imodzi ndi kanthawi kochepa, muyenera kusankha mlingo wa mitundu yonse ya insulin kuti mukwaniritse zomwe zili ndi shuga tsiku lonse.

Momwemonso kukonzekera kwina kwa insulin, kutalika kwa zotsatira za mankhwala a Humalog kumasiyana mwa odwala osiyanasiyana kapena nthawi zosiyanasiyana wodwala m'modzi. Pharmacodynamics ya Humalog mu ana imagwirizana ndi pharmacodynamics ake akuluakulu.

Odwala omwe ali ndi matenda a shuga a mtundu wachiwiri ndipo amatenga mankhwala akuluakulu a sulfonylurea, kugwiritsa ntchito Humalog kumapangitsa kugwa kwa hemoglobin. Humalog akamagwiritsa ntchito mitundu yonse iwiri ya matenda ashuga, pamakhala kutsika kwamitundu ya hypoglycemic usiku.

Machitidwe a glucodynamic ku Humalog samalumikizidwa ndi kuperewera kwa hepatic ndi impso. Polarity ya mankhwalawa yakhazikitsidwa ndi insulin ya anthu, komabe, mphamvu ya mankhwalawa imachitika mwachangu ndipo imakhala yocheperako.

Humalog imadziwika kuti zotsatira zake zimayamba mwachangu (pafupifupi mphindi 15) chifukwa cha kuchuluka kwa mayamwidwe, zomwe zimapangitsa kuti zizinenedwazo musanadye (m'mphindi 1 mpaka 15), pomwe insulin wamba, yomwe ili ndi nthawi yayitali yogwira ntchito, imatha kutumizidwa mu 30 -45 Mphindi pamaso chakudya.

Kutalika kwa mawonekedwe a Humalog ndikutali ndi insulin yaumunthu.

Pharmacokinetics

Ndi jekeseni wa subcutaneous, kuyamwa kwa lyspro insulin kumachitika mwachangu, Cmax yake imatheka pambuyo pa maola 1-2. Vd ya insulin popanga mankhwala ndi insulin wamba yamunthu ndiofanana, amachokera pa 0,26 mpaka 0,36 malita pa kilogalamu.

Njira yodalira shuga ya insulin: tsankho la munthu payekha pokonzekera insulin, postprandial hyperglycemia, yomwe singathe kuwongoleredwa ndi kukonzekera kwina kwa insulin.

Njira yodalira shuga yosadalira insulin: kukana mankhwala omwe amaletsa matenda ashuga omwe amamwa pakamwa (malabsorption a mankhwala ena a insulin, postprandial hyperglycemia omwe sangathe kuwongolera), kuchitapo kanthu kwa opaleshoni ndi matenda omwe amagwirizana (omwe amaphatikizana ndi matenda a shuga).

Kugwiritsa

Mlingo Humalog umatsimikiziridwa payekhapayekha. Humalog mu mawonekedwe a Mbale imayendetsedwa zonse ndimkati komanso kudzera m'mitsempha komanso intramuscularly. The humalogue mu mawonekedwe a cartridgeges ndi subcutaneous okha.Jekeseni ikuchitika mphindi 1-15 asanadye.

Mwanjira yake yoyenera, mankhwalawa amaperekedwa kamodzi pa tsiku, kuphatikiza ndi insulin kukonzekera ndi nthawi yayitali, katatu tsiku lililonse. Kukula kwa gawo limodzi sikungathe kupitirira 40. Humalog mu Mbale ikhoza kusakanikirana ndi mankhwala a insulin omwe amakhala ndi mphamvu yayitali mu syringe imodzi.

Katoniyo sanapangirepo kuphatikiza Humalog ndi insulin ina yokonzekera mmenemo ndikuigwiritsa ntchito mobwerezabwereza.

Kufunika kochepetsa mlingo wa insulin kumatha kuchitika ngati kuchepa kwamankhwala kumapangidwe azakudya, kupsinjika kwakukulu kwa thupi, mankhwala owonjezera omwe ali ndi vuto la hypoglycemic - sulfonamides, osasankha beta-blockers.

Mukamamwa clonidine, beta-blockers ndi reserpine, zizindikiro za hypoglycemic nthawi zambiri zimachitika.

Zotsatira zoyipa

Zotsatira zazikulu za mankhwalawa zimayambitsa zotsatirazi: kutuluka thukuta, mavuto atulo, chikomokere. Nthawi zina, chifuwa ndi lipodystrophy zimatha kuchitika.

Pakadali pano, palibe zovuta zoyipa za Humalog pamikhalidwe ya mayi woyembekezera komanso mluza wapezeka. Palibe maphunziro omwe adachitika.

Mkazi wazaka zakubadwa yemwe ali ndi matenda ashuga ayenera kudziwitsa dokotala za mimba yomwe yakonzekereratu kapena yomwe ikubwera. Kwa odwala matenda ashuga, mkaka wa m'mawere nthawi zina umafuna kusintha kwa insulin kapena zakudya.

Bongo

Mawonekedwe: kutsika kwa glucose wamagazi, omwe amaphatikizidwa ndi ulesi, thukuta, zimachitika mwachangu, mutu, kusanza, chisokonezo.

Chithandizo: mwa mawonekedwe ofatsa, hypoglycemia imatha kuyimitsidwa ndi kudya mkati mwa glucose kapena chinthu china kuchokera ku gulu la shuga, kapena zinthu zomwe zimakhala ndi shuga.

Hypoglycemia pamlingo wocheperako imatha kuwongoleka ndi jakisoni wa intramuscular kapena subcutaneous wa glucagon ndikuwonjezeranso mkati mwa carbohydrate pambuyo poti wodwalayo athe kukhazikika.

Odwala omwe salabadira glucagon amapatsidwa njira yowonjezera shuga. Pankhani ya chikomokere, glucagon imayendetsedwa mosavuta kapena kudzera m'mitsempha. Pokhapokha glucagon kapena njira yothetsera jakisoni wa chinthuchi, kuyikiridwa kwamkati yankho la glucose kuyenera kuchitidwa.

Wodwala akangodwalanso, amafunika kudya zakudya zopatsa mphamvu. Mungafunike kudya zakudya zam'mtsogolo, mudzafunikanso kuyang'anira wodwalayo, chifukwa pamakhala ngozi yoti mungayambenso hypoglycemia.

Humalog iyenera kusungidwa pa kutentha kwa +2 mpaka +5 (mufiriji). Kuzizira sikuvomerezeka. Bokosi kapena botolo lomwe layamba kale silingathenso kupitirira masiku 28 kutentha kwa firiji. Muyenera kuteteza Humalog ku dzuwa.

Ndizosavomerezeka kugwiritsa ntchito yankho muvuto lomwe lili ndi mawonekedwe amtambo, komanso ngati wokutidwa kapena utoto, komanso pamaso pa tizinthu totsimikizika mkati mwake.

Kuphatikiza kwa mankhwala

Mphamvu ya hypoglycemic ya mankhwalawa imachepetsedwa mukamamwa mankhwala a pakhungu a chithokomiro, beta2-adrenergic agonists, danazole, antidepressants, thiazide-mtundu diuretics, diazoxide, chlorprotixen, isoniazid, nicotinic acid, lithiamu carbonate, lithiamu carbonate.

Zotsatira za hypoglycemic za Humalog zimawonjezeka ndi beta-blockers, ethyl mowa komanso mankhwala osokoneza bongo omwe ali ndi, fenfluramine, anabolic steroids, tetracyclines, guanethine, salicylates, pakamwa hypoglycemic mankhwala, sulfonamides, ACE zoletsa ndi MAO ndi octre.

Mankhwala sayenera kusakanikirana ndi zinthu zina zomwe zimakhala ndi insulin ya nyama.

Humalog ikhoza kugwiritsidwa ntchito (kuyang'aniridwa ndi achipatala) kuphatikiza ndi insulin yaumunthu, yomwe imakhala yothandiza kwakanthawi kochepa, kapena kuphatikiza ndi mankhwala a hypoglycemic omwe amatengedwa pakamwa, omwe ndi zotumphukira za sulfonylurea.

MALANGIZO OGULITSIRA NTCHITO MIYANI

Dzinalo Lopanda Padziko Lonse

Jekeseni 100 IU / ml 3 ml

1 ml yankho lili

yogwira mankhwala - insulin lispro 100 IU / ml,

zotuluka: metacresol, glycerin, zinc oxide, sodium hydrogen phosphate, hydrochloric acid 10% kusintha pH, sodium hydroxide 10% yothetsera kusintha pH, madzi a jakisoni.

Chomveka chopanda utoto

Mankhwala ochizira matenda ashuga. Insulin ndi ma analogi ochita zinthu mwachangu.

Nambala yazosinthira mafoni nambala A10AV04

Kukhazikika kwa lyspro insulin pambuyo pa subcutaneous makonzedwe ndi pafupifupi mphindi 15, pazofunikira kwambiri kuyambira 30 mpaka 70 mphindi, kutalika kwa zochita kumachitika kuyambira maola 2 mpaka 5. Nthawi ya lyspro insulin ingasiyane kutengera mlingo, jakisoni malo, magazi, kutentha, zochitika zolimbitsa thupi ndi ena. Mwazi, lyspro insulin imamangirira ku alpha ndi beta globulins. Nthawi zambiri, kumangiriza kumangokhala 5-25%, koma kumatha kukula kwambiri pamaso pa ma antibodies a seramu omwe amawoneka munthawi ya chithandizo. Kuchulukitsa kwa kugawa kwa insulin lyspro ndikofanana ndi anthu ndipo kumakhala 0,26 - 0,36 l / kg. Lyspro insulin kagayidwe amapezeka m'chiwindi ndi impso. Mu chiwindi, pakumayenda magazi amodzi, mpaka 50% ya mlingo wochotseredwa sichitha, mu impso timadzi timadzi tomwe timasungidwa mu glomeruli ndikuwonongeka mu tubules (mpaka 30% ya mankhwala omwe akhazikika). Pansi pa 1.5% ya inshuwaransi ya lyspro imatulutsidwa mkodzo osasinthika. Hafu ya moyo ili pafupifupi ola limodzi.

Humalog ® ndi mawonekedwe a insulin yaumunthu ndipo amasiyana nayo pokhapokha potsatira kusintha kwa proline ndi lysine amino acid zotsalira pamalo 28 ndi 29 a insulin B. Chochita chachikulu cha Humalog® ndikuwongolera kwa kagayidwe ka glucose. Kuphatikiza apo, ma insulin onse ali ndi zotsatira zosiyana za anabolic komanso anti-catabolic pamitundu yambiri ya thupi. Mu minofu yamatenda ndi minyewa ina (kupatula ubongo), Humalog ® imathandizira kuyendetsa mwachangu ma glucose ndi ma amino acid, imathandizira njira ya anabolic komanso imalepheretsa mapuloteni ena. Mu chiwindi, Humalog® imawonjezera kugulitsa kwa glucose ndi masitolo a glucose mu mawonekedwe a glycogen, amalepheretsa gluconeogeneis ndikuthandizira kusintha kwa glucose owonjezera kukhala mafuta. Kuyankha kwa glucodynamic ku Humalog® sikudziyimira pawokha kwa chiwindi ndi impso. Mankhwala a Humalog® mwa ana ndi ofanana ndi akulu.

Zizindikiro zogwiritsidwa ntchito

shuga mellitus mwa akulu ndi ana opitilira zaka 3, momwe mankhwala a insulin amasonyezedwera kuti azikhala ndi matenda a homeostasis

kukhazikika kwa matenda ashuga koyambira

Mlingo ndi makonzedwe

Mlingo wa Humalog® umatsimikiziridwa ndi dokotala kutengera mtundu wa wodwalayo. Kuzindikira kwa odwala kutuluka kwina insulin ndi kosiyana, 1 unit ya insulin yomwe imayang'aniridwa mosalekeza imalimbikitsa kuyamwa kwa 2 mpaka 5 g shuga. Humalog® imalimbikitsidwa kuti iperekedwe pasanadutse kuposa mphindi 15 musanadye kapena mutangotha ​​kudya kamodzi pa tsiku (monotherapy) kapena katatu patsiku limodzi ndi insulin. Mankhwala omwe atumizidwa ayenera kukhala otentha.

Njira yoyendetsera Humalog® mwa achikulire ndi ana ndi payekha! Mlingo umodzi komanso wa tsiku ndi tsiku umasinthidwa malinga ndi zotsatira za kubwereza kwa magazi m'magazi ndi mkodzo masana komanso kutengera zomwe zimafunikira wodwala.

Zosowa za tsiku ndi tsiku za Humalog® zimatha kusiyanasiyana, nthawi zambiri ndi 0.5-1.0 IU / kg / tsiku.

Kuwongolera kwapakati pa Humalog® kumachitika ngati jekeseni wovomerezeka wamkati.Kupanga kwamitsempha kwa Humalog® kumatha kuchitika kuwongolera kuchuluka kwa shuga m'magazi a ketoacidosis, matenda apakhungu, kapena pakuchita opaleshoni komanso nthawi ya postoperative. Poterepa, nthawi zambiri ndikofunikira kulamula kuchuluka kwa shuga m'magazi. Makina a kulowetsedwa ndi kuchuluka kwa 0.1 IU / ml ndi mpaka 1 IU / ml ya Humalog® mu 0,9% sodium kolorayidi kapena 5% dextrose amakhala okhazikika kutentha kwa chipinda kwa maola 48.

Mwa kulowetsedwa kwa humaloga ndi pampu ya insulin, malangizo a pampu ayenera kutsatiridwa mosamalitsa. Njira yolowetsera imasinthidwa maola 48 aliwonse. Ngati hypoglycemia ikukula, kulowetsaku kumatha. Mukamagwiritsa ntchito pampu, Humalog® sayenera kusakanikirana ndi ma insulini ena.

Jakisoni wotsekemera amayenera kuperekedwa kwa mapewa, m'chiuno, matako kapena pamimba. Masamba a jakisoni amayenera kusinthidwa kuti malo omwewo sawagwiritsanso ntchito mwina kamodzi pamwezi. Mothandizidwa ndi hypodermic ya Humalog®, chisamaliro chimayenera kutengedwa kuti choteteza kulowa mu jakisoni. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa .. Odwala ayenera kuphunzitsidwa njira yoyenera yoyendetsera insulin.

Ma cartridge a Humalog® safuna kupatsidwanso mphamvu ndipo akhoza kugwiritsidwa ntchito pokhapokha ngati zomwe zili bwino ndizopanda madzi, zopanda ma cell.

Osagwiritsa ntchito ngati ali ndi ma flakes. Ma kapangidwe ka makatoni amalola kuti zomwe zili mkati mwake zisakanikirane ndi ma insulin enanso mwachindunji mu cartridge palokha. Makatoniwo sanapangidwe kuti adzazitsidwe. Tsatirani malangizo a wopanga pa cholembera chilichonse mukadzazitsa katoni, ndikulowetsa singano, komanso jakisoni wa insulin.

Sankhani tsamba la jakisoni.

Pukuta khungu pamalo opukutira ndi thonje la thonje.

Chotsani kapu yakunja yoteteza ku singano.

Sinthani khungu lanu pokoka kapena kulikhomera kukhala khola lalikulu.

Ikani singano ndi jakisoni.

Chotsani singano ndikudikirira pang'ono malo a jekeseni kwa masekondi angapo. Osatupa malo a jakisoni.

Pogwiritsa ntchito singano yakunja, mutangoyambitsa mankhwalawo, gulani singano ndikuyipeza pamalo otetezeka.

Ndikofunikira kusinthana mawebusayiti enanso mwanjira yoti malo omwewo sagwiritsidwe ntchito kopitilira kamodzi pamwezi.

Osasakaniza yankho la insulini mu Mbale ndi insulin m'makalata.

Zotsatira zoyipa zomwe zidachitika nthawi zambiri kuposa zomwe zimachitika kamodzi zimalembedwa motsatira izi: Nthawi zambiri (≥ 10%), nthawi zambiri (≥ 1%, 0.1%, 0.01%, 0.1%, 0.01% Fomu ya Mlingo: & nbsp yankho la kupangika kwamkati ndi makonzedwe ake:

1 ml muli:

ntchito yogwira : insulin lispro 100 ME,

obwera : glycerol (glycerin) 16 mg, metacresol 3.15 mg, zinc oxide q .s. pazambiri za Zn ++ 0.0197 mg, sodium hydrogen phosphate heptahydrate 1.88 mg, hydrochloric acid solution 10% ndi / kapena sodium hydroxide solution 10% q .s. kuti pH 7.0-8.0, madzi a jekeseni q .s. mpaka 1 ml.

Yankho lomveka bwino, lopanda utoto.

Gulu la Pharmacotherapeutic: wothandizila wa hypoglycemic - wothandizira insulin analog ATX: & nbsp

A.10.A.D.04 Insulin LizPro

Humalog® ndi DNA yomwe imapangidwanso ndi insulin ya anthu. Amasiyana ndi insulin yaumunthu mu kusintha kwama amino acid m'malo 28 ndi 29 a insulin B.

Chochita chachikulu cha insulin lyspro ndi malamulo a kagayidwe ka glucose. Kuphatikiza apo, imakhala ndi anabolic komanso anti-catabolic zotsatira zosiyanasiyana zamthupi. Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa ma amino acid, koma nthawi yomweyo kumachepa mu glycogenolysis, gluconeogeneis, ketogeneis, lipolysis, proteinabolism ndi kutulutsidwa kwa ma amino acid.

Zimawonetsedwa kuti ndizofanana ndi insulin yaumunthu, koma zochita zake zimachitika mwachangu kwambiri ndikukhalitsa kwakanthawi.

Lyspro insulin imadziwika ndi kuyamba mwachangu (pafupifupi mphindi 15), popeza imakhala ndi kuchuluka kwa mayamwidwe, ndipo izi zimaloleza kuti ziziperekedwa nthawi yomweyo musanadye (0-15 mphindi musanadye), mosiyana ndi insulin yokhazikika (mphindi 30-45) asanadye). imapereka mphamvu yake mwachangu ndipo imakhala ndi nthawi yofupikirako (kuyambira maola 2 mpaka 5) poyerekeza ndi insulin wamba.

Odwala omwe ali ndi mtundu woyamba 1 ndi mtundu 2 matenda a shuga, hyperglycemia yomwe imachitika pambuyo pakumayamwa amachepetsa kwambiri ndi lyspro poyerekeza ndi insulin yaumunthu. Kwa odwala omwe amalandila insulin yochepa komanso woyambira insulin, ndikofunikira kusankha inshuwarini yonse kuti mupeze kuchuluka kwakukulu kwa shuga m'magazi tsiku lonse.

Monga momwe akukonzekera insulin yonse, kutalika kwa nthawi ya lyspro insulin kumatha kukhala kosiyanasiyana mwa odwala kapena nthawi zosiyanasiyana wodwala yemweyo ndipo zimatengera mlingo, malo a jakisoni, magazi, kutentha kwa thupi ndi zochitika zolimbitsa thupi. Mankhwala a lyspro insulin mwa ana ndi achinyamata ali ofanana ndi omwe amawonekera mwa akulu.

Odwala omwe ali ndi matenda a shuga a 2 alandila Mlingo wambiri wa sulfonylurea, kuwonjezera kwa insulin kumabweretsa kuchepa kwakukulu kwa hemoglobin ya glycosylated.

Mankhwala a Lyspro insulin kwa odwala omwe ali ndi matenda amtundu wa 2 ndi mtundu wa 2 amaphatikizidwa ndi kuchepa kwa ziwonetsero za nocturnal hypoglycemia.

Kuyankha kwa glucodynamic sikudalira kulephera kwa impso kapena chiwindi.

Pambuyo pothandizidwa ndi subcutaneous, imalowetsedwa mwachangu ndikufika pakuloweka kwambiri m'magazi pambuyo pa mphindi 30-70.

Kuchulukitsa kwa insulin lispro kumakhala kofanana ndi kuchuluka kwa magawidwe wamba a insulin anthu ndipo ali mulingo wa 0.26-0.36 l / kg

Ndi subcutaneous makonzedwe, theka la moyo wa insulin lispro ili pafupifupi ola limodzi.

Odwala aimpso ndi hepatic kusowa, kuchuluka kwa mayamwa lyspro kumakhalabe kuyerekezera ndi wamba insulin.

Matenda a shuga amapezeka mwa akulu ndi ana, omwe amafunikira chithandizo cha insulin kuti akhalebe ndi shuga.

Hypersensitivity to lyspro insulin kapena aliyense wokonda.

Mimba ndi kuyamwa:

Pakadali pano, palibe zotsatira zosasangalatsa za Lyspro insulin pa mimba kapena thanzi la mwana wosabadwa / wakhanda. Mpaka pano, palibe kafukufuku wothandiza yemwe adachitika.

Pakati pa nthawi yayitali, chinthu chachikulu ndikukhazikitsa chitetezo chabwino cha glycemic mwa odwala matenda a shuga omwe akulandira chithandizo ndi insulin. Kufunika kwa insulin nthawi zambiri kumachepetsa panthawi yoyambirira ndikuwonjezeka panthawi yachiwiri komanso yachitatu. Nthawi yobadwa pambuyo pokhapokha ndipo mwayamba kubadwa, zofunika za insulin zimatha kugwa kwambiri. Odwala omwe ali ndi matenda ashuga ayenera kukaonana ndi dokotala ngati pakati pachitika kapena akukonzekera. Pankhani ya mimba kwa odwala omwe ali ndi matenda ashuga, chinthu chachikulu ndikuwunika shuga, komanso thanzi lathunthu.

Kwa odwala matenda a shuga nthawi yoyamwitsa, zingakhale zofunikira kusankha kuchuluka kwa insulin, zakudya, kapena zonse ziwiri.

Mlingo ndi makonzedwe:

Mlingo wa Humalog® umatsimikiziridwa ndi dokotala aliyense payekha, kutengera kuchuluka kwa shuga m'magazi. Ndondomeko ya insulin makonzedwe ali payekha. Humalog® imatha kuperekedweratu chakudya chisanafike. Ngati ndi kotheka, Humalog® imatha kutumikiridwa patangotha ​​chakudya. Kutentha kwa mankhwala omwe amaperekedwa kuyenera kukhala kutentha kwambiri.

Humalog® iyenera kutumikiridwa ngati jakisoni wofunda kapena ngati kulowetsedwa kofikira pogwiritsa ntchito pampu ya insulin. Ngati ndi kotheka (ketoacidosis, matenda owopsa, nthawi pakati pa ntchito kapena nthawi yothandizira), kukonzekera kwa Humalog® amathanso kuthandizira.

Subcutaneally ayenera jekeseni phewa, ntchafu, matako kapena m'mimba. Masamba a jakisoni amayenera kusinthidwa kuti malo omwewo asagwiritsidwerenso kuposa nthawi 1 pamwezi.

Ndi subcutaneous makonzedwe a Humalog®, chisamaliro chiyenera kutengedwa kuti mankhwalawo asalowe mumtsempha wamagazi. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Wodwala ayenera kuphunzitsidwa njira yolondola ya jakisoni.

Malangizo a kuperekera mankhwala Humalog®

a) Kukonzekera koyambitsa

Yankho la Humalog liyenera kukhala lomveka komanso lopanda utoto. Osagwiritsa ntchito yankho la Humalog® ngati ndi mitambo, yothina, yopanda utoto, kapena tinthu tating'onoting'ono tadziwika.

Mukakhazikitsa cartridge mu syringe cholembera, ndikukhala ndi singano ndikulowetsa insulin, tsatirani malangizo a wopanga omwe akuphatikizidwa ndi cholembera chilichonse.

2. Sankhani tsamba la jakisoni.

3. Pukuta khungu pamalo opaka jekeseni.

4. Chotsani kapu ku singano.

5. Konzani khungu pakukoka kapena kulisonkhanitsani khola lalikulu. Ikani singano molingana ndi malangizo ogwiritsa ntchito cholembera.

6. Kanikizani batani.

7. Chotsani singano ndikufinya pang'onopang'ono malo opaka jakisoni ndi swab ya thonje kwa masekondi angapo. Osatupa malo a jakisoni.

8. Pogwiritsa ntchito chopukutira cha singano, tulutsani singano ndikuitaya.

9. Masamba obayira enanso kuti malo omwewo sawagwiritsanso ntchito kamodzi pamwezi.

Za mankhwalawa Humalog® mu syringe yachangu™

Musanapereke insulin, muyenera kuwerenga Malangizo a QuickPen ™ Syringe pen Institions for Use.

c) Mitsempha ya insulin

Kubayidwa kwapakati pa kukonzekera kwa Humalog® kuyenera kuchitika molingana ndi chizolowezi chachipatala cha jakisoni wamkati, mwachitsanzo, kulowetsedwa kwa bolus kapena kugwiritsa ntchito kulowetsedwa. Poterepa, nthawi zambiri ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi.

Makina a kulowetsedwa ndi zozungulira kuchokera ku 0.1 IU / ml mpaka 1.0 IU / ml ya insulin lispro mu 0,9% sodium chloride solution kapena 5% dextrose amakhala okhazikika kutentha kwa chipinda kwa maola 48.

d) kulowetsedwa kwa insulin

Potengera kulowetsedwa kwa Humalog®, mapampu Ochepera ndi Disetronic angagwiritsidwe ntchito kulowetsedwa kwa insulin. Muyenera kutsatira mosamalitsa malangizo omwe abwera ndi pampu. Njira ya kulowetsedwa imasinthidwa maola 48 aliwonse. Mukalumikiza dongosolo la kulowetsedwa, samalani malamulo aseptic. Pakachitika vuto la hypoglycemic, kulowetsaku kumayimitsidwa mpaka gawo litatsimikiza. Ngati shuga wambiri m'magazi adziwika, ndikofunikira kudziwitsa dokotala za izi ndikupereka kuchepa kapena kufooka kwa kulowetsedwa kwa insulin.

Kuperewera kwa mpope kapena njira yophika yolumikizidwa kungapangitse kuti chiwopsezo cha glucose chiwonjezeke msanga. Ngati mukukayikira kuti ndikuphwanya kupereka kwa insulin, muyenera kutsatira malangizowo ndipo ngati kuli koyenera dziwitsani adokotala. Mukamagwiritsa ntchito pampu, kukonzekera kwa Humalog® sikuyenera kusakanikirana ndi ma insulini ena.

Hypoglycemia Matenda a shuga ndi omwe amapezeka odwala kwambiri. Hypoglycemia yayikulu imatha kutha mphamvu ya chikumbumtima (hypoglycemic chikomokere), ndipo, mwatsatanetsatane, kufa.

Odwala amatha thupi lawo siligwirizana mwanjira yofiyira, kutupa, kapena kuyunkhira pamalo a jekeseni. Nthawi zambiri, zizindikirozi zimatha patatha masiku angapo kapena milungu. Nthawi zambiri sizichitika osiyanasiyana thupi lawo siligwirizana pomwe kuyabwa kumachitika mthupi lonse, urticaria, angioedema, malungo, kufupika, kutsika magazi, tachycardia, kuchuluka thukuta. Milandu ingapo yamomwe thupi limagwirira ntchito ikhoza kukhala yowopsa pamoyo.

Tsamba la jekeseni limatha lipodystrophy.

Milandu yachitukuko yadziwika. edema makamaka ndi kufalikira kwamphamvu kwa shuga m'magazi poyimilira komwe kuli kwambiri mankhwala a insulini oyamba osakhutiritsa glycemic control (onani gawo "Malangizo Apadera").

Mankhwala osokoneza bongo amaphatikizidwa ndi chitukuko Zizindikiro za hypoglycemia : ulesi, thukuta, njala, kugwedezeka, tachycardia, mutu, chizungulire, masomphenya osasunthika, kusanza, chisokonezo.

Zolemba zofatsa Amayimitsidwa ndi kumwa kwa shuga kapena shuga wina, kapena zinthu zina zokhala ndi shuga (tikulimbikitsidwa kuti nthawi zonse muzikhala ndi shuga g). About hypoglycemia yosamutsidwa ndikofunikira kudziwitsa dokotala.

Kuwongolera kwambiri hypoglycemia angathe kuchitidwa ntchito mu mnofu kapena subcutaneous makonzedwe a glucagon, kenako ingestion wa chakudya pambuyo kukhazikika kwa wodwalayo. Odwala omwe samayankha amalumikizidwa ndi jekeseni ya dextrose (glucose) kudzera m'mitsempha.

Ngati wodwala ali comatose , iyenera kuperekedwa mwachisawawa kapena mosazungulira. Popanda glucagon kapena ngati palibe chochita ndi momwe amayambitsira, ndikofunikira kupaka yankho la dextrose kudzera m'mitsempha. Atangochira - chikumbumtima, wodwalayo ayenera kupatsidwa chakudya chopatsa thanzi. Kudya zakudya zowonjezera zamagalimoto ndi kuwunika kwa wodwalayo kungafunike, popeza kuyambiranso kwa hypoglycemia ndikotheka.

About hypoglycemia yosamutsidwa ndikofunikira kudziwitsa dokotala.

Kuopsa kwa hypoglycemic kanthu kumachepetsedwa akaphatikizana ndi mankhwala otsatirawa : kulera kwapakamwa, glucocorticosteroids, mahomoni okhala ndi chithokomiro, beta 2 --adrenomimetics (mwachitsanzo, ritodrin, terbutaline), ma tridclic antidepressants, thiazide diuretics, diazoxide, phenothiazine.

Kuopsa kwa hypoglycemic zochita kumakulaMukamagwirizana ndi mankhwala otsatirawa : beta-blockers, ndi mankhwala okhala ndi ethanol, mankhwala a anabolic, fenfluramine, guanethidine, tetracyclines, mankhwala a m'kamwa a hypoglycemic, salicylates (mwachitsanzo), mankhwala a sulfonamide, ena antidepressants (monoamine oxidase inhibitors), angiotensin inhibitors, angiotensin inhibitorsin, angiotensin inhibitors . Humalog® sayenera kusakanikirana ndi kukonzekera kwa insulin ya nyama.

Mukamamwa mankhwala ena osakanikirana ndi Humalog®, muyenera kufunsa dokotala.

Ngati mukufunika kugwiritsa ntchito mankhwala ena, kuphatikiza insulin, muyenera kufunsa dokotala (onani gawo "Malangizo apadera").

Kusamutsa wodwala kupita ku mtundu wina kapena mtundu wa insulin kuyenera kuchitika moyang'aniridwa ndi achipatala. Kusintha kwa zochitika, mtundu (wopanga), mtundu (Wokhazikika, NPH, ndi zina), mitundu (nyama, munthu, insulin analogue) ndi / kapena njira yopanga (DNA recombinant insulin kapena insulini yachikhalidwe) imatha kutsogolera kufunika kosintha mlingo.

Mikhalidwe yomwe zizindikiro zoyambirira za hypoglycemia zitha kukhala zosakhudzika komanso zochepa zomwe zimaphatikizidwa zimaphatikizapo kukhalapo kwa matenda osokoneza bongo, chidziwitso cha insulin, matenda amanjenje mu matenda osokoneza bongo, kapena mankhwala monga beta-blockers.

Odwala omwe ali ndi vuto la hypoglycemic atasamutsidwa kuchokera ku insulin yochokera ku nyama kupita ku insulin yaumunthu, zizindikiro zoyambirira za hypoglycemia zitha kutchulidwa pang'ono kapena zosiyana ndi zomwe adakumana nazo kale ndi insulin. Hypoglycemic yosasinthika kapena ma hyperglycemic zomwe zimachitika zimatha kuyambitsa chikumbumtima, chikomokere, kapena kufa. Mlingo wosakwanira kapena kusiya kulandira chithandizo, makamaka kwa odwala omwe ali ndi matenda a shuga a I, angayambitse hyperglycemia ndi matenda ashuga a ketoacidosis - mikhalidwe yomwe ikhoza kuwopsa kwa wodwalayo.

Kufunika kwa insulin kumatha kuchepa ngati kulephera kwa impso, komanso kwa odwala omwe ali ndi vuto la kuchepa kwa chiwindi chifukwa cha kuchepa kwa njira ya gluconeogeneis ndi insulin metabolism. Komabe, mwa odwala omwe ali ndi vuto losatha la chiwindi, kukana kwa insulini kungayambitse kuchuluka kwa insulin. Kufunika kwa insulin kumatha kuwonjezeka panthawi yomwe matenda opatsirana, ndi nkhawa, komanso kuchuluka kwa chakudya chamagulu.

Kusintha kwa mlingo kumafunikanso ngati wodwala akuchulukitsa kapena kusintha kwachilendo kwa zakudya. Kuchita masewera olimbitsa thupi mutangotha ​​kudya kumatha kuwonjezera ngozi ya hypoglycemia. Zotsatira za pharmacodynamics za analogs za insulin yogwira ntchito yaumunthu ndikuti ngati hypoglycemia imayamba, ndiye kuti itha kupanga jekeseni m'mbuyomu kuposa jakisoni wa insulle ya munthu wosungunuka.

Ngati dokotala wakupangirani kukonzekera kwa insulini ndi kuchuluka kwa 40 IU / ml mu vial, simuyenera kutenga insulini kuchokera ku cartridge ndi insulin ndende ya 100 IU / ml pogwiritsa ntchito syringe ya jekeseni wa insulin ndi 40 IU / ml.

Mukamagwiritsa ntchito insulin pokonzekera limodzi ndi mankhwala a gulu la thiazolidinedione, chiopsezo chotenga matenda a edema ndi matenda a mtima omwe amalephera chikuwonjezereka, makamaka kwa odwala omwe ali ndi matenda amtima komanso kupezeka kwa zinthu zomwe zingayambitse matenda osalephera a mtima.

MANTHA OGWIRA NTCHITO MALO OGWIRA NTCHITOQuickPen ™

Humalog® QuickPen ™, Humalog® Mix 25 QuickPen ™, Humalog® Mix 50 QuickPen ™

MALANGIZO OTHANDIZA MALO OTSATIRA

CESANI LERANI ZINSINSI izi ASANAYITSE

Quick Pen Syringe chole ndi yosavuta kugwiritsa ntchito. Ndi chipangizo chothandizira kuperekera insulin (cholembera insulini cholembera) yomwe ili ndi 3 ml (ma 300) pakukonzekera kwa insulin ndi ntchito ya 100 IU / ml. Mutha kubaya kuchokera 1 mpaka 60 magawo a insulin pa jakisoni. Mutha kukhazikitsa mlingo molondola ndi umodzi. Ngati mwayika mayunitsi ambiri. Mutha kukonza mankhwalawa osataya insulin.

Musanagwiritse ntchito syPinge ya QuickPen, werengani bukuli ndikutsatira malangizo ake ndendende. Ngati simutsatira malangizowa, mutha kulandira inshuwaransi yotsika kwambiri kapena kwambiri.

Pulogalamu yanu ya insulin ya QuickPen iyenera kugwiritsidwa ntchito povulala panu. Osapatsira cholembera kapena singano kwa ena, chifukwa izi zimatha kufalitsa kachilomboka. Gwiritsani ntchito singano yatsopano jekeseni iliyonse.

Musagwiritse ntchito cholembera ngati gawo lake lina lawonongeka kapena lawonongeka. Nthawi zonse tengani cholembera chopanda kanthu ngati mungataye cholembera kapena chikaonongeka.

Kukonzekera Kwachangu kwa Syninge

Werengani ndikutsatira malangizo ogwiritsira ntchito mankhwalawa.

Onani cholembera pa cholembera asanalowe jakisoni iliyonse kuti muwonetsetse kuti tsiku lakelo linatha ndipo mukugwiritsa ntchito mtundu woyenera wa insulini, musachotse chizindikiro pa cholembera.

Zindikirani : Mtundu wa batani lothamanga la cholembera cha QuickPen umagwirizana ndi mtundu wa Mzere pa cholembera cholembera ndipo zimatengera mtundu wa insulin.Mu buku ili, batani la mlingo limayimitsidwa. Mtundu wamtambo wa cholembera cha syringe wa QuickPen umaonetsa kuti umapangidwa kuti ugwiritse ntchito ndi zinthu za Humalog.

Dokotala wanu wakupangira mtundu wa insulin wabwino kwambiri. Kusintha kulikonse kwa mankhwala a insulin kuyenera kuchitidwa kokha moyang'aniridwa ndi dokotala.

Musanagwiritse ntchito cholembera, onetsetsani kuti singanoyo imalumikizidwa kwathunthu ndi cholembera.

Tsatirani malangizo omwe aperekedwa apa.

Mafunso omwe amafunsidwa pafupipafupi okonzekera kukonzekera Penti ya QuickPen Syringe kuti mugwiritse ntchito

-Kodi kukonzekera kwanga kwa insulin kuyenera kuwoneka bwanji? Kukonzekera kwina kwa insulin ndi kuyimitsidwa kogwiritsa, pomwe ena ndi mayankho omveka, onetsetsani kuti mukuwerenga malongosoledwe a insulin m'mawu omwe aikidwa kuti mugwiritse ntchito.

- Ndichite chiyani ngati mlingo wanga waposa 60? Ngati mlingo womwe wakupatsani uli pamwamba pa mayunitsi 60, mufunika jekeseni wachiwiri, kapena mutha kulankhulana ndi dokotala za nkhaniyi.

- Chifukwa chiyani ndigwiritse ntchito singano yatsopano pa jekeseni iliyonse? Ngati singano agwiritsidwanso ntchito, mutha kulandira mulingo wolakwika wa insulin, singano imatsekedwa, kapena cholembera chimatha, kapena mutha kutenga kachilombo chifukwa cha zovuta zina.

- Ndichite chiyani ngati sinditsimikiza kuchuluka kwa insulini yanga ? Kwezani chogwirira kuti nsonga ya singano ilowe pansi. Mulingo wapa cartridge wosonyeza bwino kuchuluka kwa insulini yotsalira. Manambalawa ASATHA kugwiritsidwa ntchito kukhazikitsa mlingo.

"Ndichite chiyani ngati sindingathe kuchotsa cholembera ku cholembera?" Kuti muchotse chipewa, kokerani. Ngati mukuvutikira kuchotsa chipewa, sinthani mosamala kachulukidwe kake ndi kuyerekezera kuti mumasule, ndiye kuti mukoka kuti muchotse kapuyo.

Kuyang'ana cholembera cha SyPinge cha QuickPen cha Insulin

Onani kuchuluka kwanu kwa insulin nthawi zonse. Chitsimikizo cha kutulutsidwa kwa insulini kuchokera ku cholembera, iyenera kuchitidwa jakisoni aliyense asanafike pang'onong'ono wa insulin kuti awonetsetse kuti cholembera chakonzeka.

Ngati simukuyang'ana insulin yanu musanayambe kudwala, mutha kulandira insulin yochepa kwambiri kapena yambiri.

Mafunso Omwe Amakonda Kufunsa za Kuchita Macheke a Insulin

- Chifukwa chiyani ndiyenera kuwerengera insulin yanga isanadye jakisoni iliyonse?

1. Izi zikuwonetsetsa kuti cholembera chakonzekera kumwa.

2. Izi zikutsimikizira kuti chinyengo cha insulin chimatuluka mu singano mukakanikiza batani la mlingo.

3. Izi zimachotsa mpweya womwe ungatenge mu singano kapena katoni ya insulin panthawi yovomerezeka.

- Ndiyenera kuchita chiyani ngati sindingathe kukanikiza bwino batani la mlingo panthawi yachangu ya insulin?

1. Phatikizani singano yatsopano.

2. Yang'anani insulin kuchokera ku cholembera.

"Ndichitenji ndikawona makamu am'kati mwa katiriji?"

Muyenera kufufuza insulin kuchokera ku cholembera. Kumbukirani kuti simungasunge cholembera ndi singano yolumikizidwa, chifukwa izi zimatha kupangitsa kuti pakhale thovu. Khungu laling'ono la mpweya silikuwakhudza mankhwalawo, ndipo mutha kulowa muyezo wanu mwachizolowezi.

Kukhazikitsidwa kwa mlingo wofunikira

Tsatirani malamulo a asepsis ndi antiseptics omwe adokotala amuuzani.

Onetsetsani kuti mwalowa muyezo wofunikira mwa kukanikiza ndikuyika batani la mlingo ndikuwerengera pang'onopang'ono mpaka 5 musanachotsere singano. Ngati insulin ikudontha kuchokera singano, mwina simunagwire singano pansi pa khungu lanu nthawi yayitali.

Kukhala ndi dontho la insulin pamsana pa singano ndikwabwinobwino. Izi sizingakhudze mlingo wanu.

Cholembera cha syringe sichingakulolezeni kujambula mlingo wopitilira muyeso wamagulu a insulin otsalira mu katoni.

Ngati mukukayika kuti mwapereka mlingo wonse, musamaperekenso mlingo wina. Imbani woimira wanu wa Lilly kapena dokotala wanu kuti akuthandizeni.

Ngati mlingo wanu uposa kuchuluka kwa zigawo zomwe zatsalira mu cartridge, mutha kuyika kuchuluka kwa insulini mu cholembera ichi ndipo mugwiritse ntchito cholembera chatsopano kuti mumalize muyeso wofunikira, Pena lembani mlingo wonse pogwiritsa ntchito cholembera chatsopano.

Osayesa kubaya insulin potembenuza batani la mlingo. Simulandila insulin ngati mutembenuza batani la mlingo. Muyenera kusinthitsa batani la mlingo molunjika kuti mulandire mlingo wa insulin.

Musayese kusintha mlingo wa insulin panthawi ya jakisoni.

Singano yomwe imagwiritsidwa ntchito iyenera kutayidwa malinga ndi zofunikira zotaya zinyalala zakuchipatala.

Chotsani singano pambuyo pa jekeseni iliyonse.

Mafunso Ofunsidwa Kawirikawiri

- Chifukwa chovuta kukanikiza batani la mlingo, ndikuyesera liti kubaya?

1. Singano yanu itha kumangidwa. Yesani kuphatikiza singano yatsopano. Mukachita izi, mutha kuwona momwe insulin imatuluka mu singano. Kenako yang'anani cholembera.

2. Makina osindikiza mwachangu pa batani la mlingo amatha kupangitsa batani kukanikiza. Kutsinikiza pang'onopang'ono batani la mlingo kungapangitse kukanikiza mosavuta.

3. Kugwiritsa ntchito singano yayikulu kukuthandizira kuti musakanize kubatani.

Funsani othandizira anu azaumoyo za kukula kwaku singano kopambana.

4. Ngati kukanikiza batani pakati pa dongosolo la kumwa kumakhalirabe zolimba pambuyo poti mfundo zonse pamwambazi zithe, ndiye kuti cholembera sichingasinthidwe.

- Ndiyenera kuchita chiyani ngati syringe yachala ya Peneni ikagwiritsidwa ntchito?

Cholembera chako chidzakhala cholimba ngati nkovuta kuti ugwiritse kapena kubayira. Popewa cholembera kuti chisamatirire:

1. Phatikizani singano yatsopano. Mukachita izi, mutha kuwona momwe insulin imatuluka mu singano.

2. Chongani insulin.

3. Ikani mlingo wofunikira ndi jakisoni.

Musayesere kupaka cholembera, chifukwa izi zitha kuwononga gawo la cholembera.

Kukanikiza batani la mlingo kumatha kulowa ngati zinthu zakunja (dothi, fumbi, chakudya, insulini kapena zakumwa zilizonse) zikalowa mkatikati mwa syringe. Musalole zodetsa kuti zilowe mu cholembera.

- Chifukwa chiyani insulini imatuluka mu singano nditamaliza kupereka mlingo wanga?

Mwina mwachotsa singano mwachangu kwambiri pakhungu.

1. Onetsetsani kuti mukuwona nambala ya "0" pazenera la chisonyezo.

2. Kupereka mlingo wotsatira, kanikizani ndikuyika batani la mlingo ndikuwerengera pang'onopang'ono mpaka 5 musanachotsere singano.

- Ndichitenji ngati mlingo wanga wayikidwa, ndipo batani loyamwa mwanjira mwangozi limakumbukiranso mkatikati popanda singano yolumikizidwa ndi cholembera?

1. Sinthani batani la mlingo kukhala zero.

2. Phatikizani singano yatsopano.

3. Chitani insulin.

4. Ikani mlingo ndi jakisoni.

- Ndingatani ngati nditayikapo mlingo woyipa (wotsika kwambiri kapena wotsika kwambiri)? Sinthani batani la mlingo kumbuyo kapena kutsogolo kuti mukonze uthengawo.

- Ndichitenji ngati nditaona kuti insulini imatuluka m'chimangirizo panthawi ya kusankha kapena kusintha kwa mankhwala? Musamapereke mlingo, chifukwa mwina simungalandire mlingo wathunthu. Khazikitsani cholembera ku nambala ya zero ndikuyang'ananso kuchuluka kwa insulini kuchokera ku cholembera (onani gawo "Kuyang'ana Pangongole Yotumizira Ya QuickPen Kuti Ipatsidwe Insulin"). Khazikitsani mlingo woyenera ndi jakisoni.

- Ndichite chiyani ngati kumwa kwathunthu sikukwaniritsidwa? Cholembera sichingakulorerenso kukhazikitsa mlingo wowonjezera wa kuchuluka kwa magawo a insulin omwe atsalira mukatoni. Mwachitsanzo, ngati mukufuna mayunitsi 31, ndipo magawo 25 okha atsala mu katiriji, ndiye kuti simungathe kudutsa nambala 25 mukamayikiratu. Osayesa kukhazikitsa mlingowo podutsa nambala iyi. Ngati gawo loyenera latsala m'khola, mutha:

1. Lowetsani gawo ili, kenaka lembani mlingo wotsalira pogwiritsa ntchito cholembera chatsopano, kapena

2. Lowetsani mlingo wathunthu kuchokera ku cholembera chatsopano.

- Chifukwa chiyani sindingathe kukhazikitsa mlingo kuti mugwiritse ntchito insulin yaying'ono yomwe yasiyidwa mu katiriji yanga? Cholembera chimbalecho chimapangidwa kuti chilolere kuyamwa kwa magawo 300 a insulin. Chida cha cholembera sichitha kuteteza katiriji kuti lisatheretu, chifukwa kuchuluka kwa insulini komwe kumakhalabe ndi kathumba sikungavulazidwe ndikulondola.

Kusunga ndi kutaya

Cholembera sichingagwiritsidwe ntchito ngati chakhala kunja kwa firiji kwa nthawi yopitilira nthawi yodziwika m'Malamulo Ogwiritsa Ntchito.

Osasunga cholembera ndi singano yake. Ngati singano yatsala kuti ikanikizidwe, insulin ingatuluke m'timalo, kapena insulini itha kuwuma mkati mwa singano, ndikupangitsa kuti singano iduke, kapena kuti thovu la mpweya lithe mkati mwa cartridge.

Zilembera zomwe sizikugwiritsidwa ntchito ziyenera kusungidwa mufiriji kutentha kwa 2 ° C mpaka 8 ° C. Osagwiritsa ntchito cholembera kuti chitauma.

Cholembera cha syringe chomwe mukugwiritsa ntchito pano chiyenera kusungidwa pa kutentha osaposa 30 ° C komanso pamalo otetezedwa kuti asatenthe ndi kutentha.

Fotokozerani Malangizowo kuti mugwiritse ntchito pozindikira bwino malo osungirako cholembera.

Sungani cholembera kuti chisafike kwa ana.

Taya singano zogwiritsidwa ntchito polemba-maumboni, zopangira zofananira (mwachitsanzo, zotengera zama biohazardous zvinhu kapena zinyalala), kapena monga momwe katswiri wanu wazachipatala adakulimbikitsira.

Taya zolembera zomwe mugwiritse ntchito singano popanda singano zophatikizidwa kwa iwo komanso mogwirizana ndi malingaliro a dokotala.

Osabwezanso zotengera zazitali.

Funsani dokotala wanu za momwe mungathere kutaya zotengera zotayidwa m'dera lanu.

Humalog ®, Humalog ® in the QuickPen ™ syringe cholembera, Humalog® Mix 50 mu cholembera cha syringe ya QuickPen ™, Humalog® Mix 25 mu cholembera chiphaso cha QuickPen ™ ndi zizindikiro za Eli Lilly ndi Company.

The QuickPen ™ Syringe pen imakwaniritsa zofunikira zenizeni za dosing ndi zofunikira za ISO 11608 1: 2000

Onetsetsani kuti muli ndi zinthu zotsatirazi:

□ Kuthamangitsa Pen Syringe

□ Chingwe chatsopano cha cholembera

□ Swab wothira mowa

Zophatikizira ndi Zingwe za QuickPen Syringe * onani chithunzi 3 .

Kukongoletsa Mtundu wa Dzu Lobatani - onani chithunzi 2 .

Kugwiritsa ntchito cholembera

Tsatirani malangizo awa kuti mumalize jakisoni aliyense.

1. Kukonzekera kwa Syninge Yachangu

Kokani kapu ya cholembera kuti muchotse. Osazungulira kapu. Osachotsa cholembera ku cholembera.

Onetsetsani kuti mwayang'ana insulini yanu:

Tsiku lotha ntchito

Chidwi: Nthawi zonse werengani cholembera cholembera kuti onetsetsani kuti mukugwiritsa ntchito mtundu woyenera wa insulin.

Kwa kuyimitsidwa kwa insulin kokha:

Lungunulani cholembera maulendo 10 pakati pama manja anu

tembenuza cholembera maulendo 10.

Kusakaniza ndikofunikira kuti mukhale otsimikiza kuti mupeze mlingo woyenera. Insulin iyenera kuwoneka yosakanikirana.

Tengani singano yatsopano.

Chotsani chomata papepala ndi singano yakunja.

Gwiritsani ntchito swab wothira mowa kuti mupukutire disc ya mphira kumapeto kwa cholembera.

Valani singano mu cap kulondola pamphepete mwa cholembera.

Skani pa singano kufikira mutalumikizidwa kwathunthu.

2. Kuyang'ana cholembera cha QuickPen Syringe cholembera Insulin

Chenjezo: Ngati simukuyang'ana insulin musanadye jakisoni iliyonse, mutha kutsika kwambiri kapena kutsika kwambiri ndi insulin.

Chotsani singano yakunja. Osataya.

Chotsani thumba lamkati la singano ndikuitaya.

Khazikitsani magulu awiri mutembenuza batani la mlingo.

Lowetsani cholembera.

Dinani pazosungira cartridge kuti mulole mpweya kuti utuluke

Ndi singano ikuloza, kanikizani batani la mlingo mpaka litayime ndipo nambala ya "0" ipezekere pazenera.

Gwiritsani ntchito batani la muyeso poti mwaweleranso ndipo muwerenge pang'onopang'ono mpaka 5.

Kuyang'ana kudya kwa insulin kumawonedwa ngati kwathunthu ngati insulin ikupezeka kumapeto kwa singano.

Ngati phula la insulin silikuwoneka kumapeto kwa singano, ndiye kuti mubwereze njira zomwe mungayang'anirenso insulin kanayi, kuyambira pa point 2B ndikutha ndi point 2G.

Chidziwitso: Ngati simukuwona kupsinjika kwa insulin ikuwoneka kuchokera ku singano, ndikuyika mankhwalawo kumakhala kovuta, ndiye kuti siyani ndi singanoyo ndikubwereza kuyang'ana kuchuluka kwa insulini kuchokera mu cholembera.

Sinthani batani la mlingo kuti mupeze chiwerengero chomwe mukufuna jakisoni.

Ngati mwayika magulu ambiri mwangozi, mutha kuwongolera uthengawo mosinthanitsa ndi batani lolowanalo.

Ikani singano pansi pa khungu pogwiritsa ntchito jakisoni yemwe dokotala wanu wakupatsani.

Ikani chala chanu pa batani la mlingo ndikulimbikira batani la mlingo mpaka litayima kwathunthu.

Kuti mulowetse mlingo wathunthu, gwiritsani batani la mlingo ndikuwerengerani pang'onopang'ono mpaka 5.

Chotsani singano pansi pa khungu.

Zindikirani : Yang'anani ndikuonetsetsa kuti mukuwona nambala ya "0" pazenera la dokotala, kuti muwonetsetse kuti mwalowa muyezo wonse.

Ikani chotseka chakunja pa singano.

Chidziwitso: Chotsani singano pambuyo pa jekeseni aliyense kuti muchepetse thovu m'malembedwe.

Osasunga cholembera ndi singano yake.

Tulutsani singano ndi chophimba chakunja ndikuitaya mogwirizana ndi malangizo a dokotala.

Ikani chipewa pa syringe cholembera, chikugwirizana ndi cholumikizira cholumikizira ndi chisonyezo cha kukoka ndi kukankhira cap mwachindunji mu axis pa cholembera.

Kuwonetsa magawo 15 (onani chithunzi 4) .

Ngakhale manambala amasindikizidwa muwindo la chizindikiro ngati manambala, manambala osamvetseka amasindikizidwa ngati mizere yolunjika pakati pa manambala.

Chidziwitso: Cholembera sichingakuloreni kukhazikitsa kuchuluka kwa mayunitsi mopitilira kuchuluka kwa zigawo zomwe zatsala mu cholembera.

Ngati mulibe chitsimikizo kuti mwapereka mlingo wonse, musamaperekenso mankhwala ena.

Kukopa pa kuthekera kuyendetsa ma transp. Wed Ndi ubweya:

Mphamvu ya wodwalayo yokhazikika komanso kuchuluka kwake momwe angachitire chifukwa cha hypoglycemia kapena hyperglycemia yolumikizana ndi njira yolakwika. Izi zitha kukhala zowopsa nthawi zomwe maluso amenewa ali ofunikira kwambiri (mwachitsanzo, kuyendetsa magalimoto kapena kugwira ntchito ndi makina).

Odwala ayenera kusamala kuti apewe hypoglycemia poyendetsa. Izi ndizofunikira kwambiri kwa odwala omwe ali ndi kuchepetsedwa kapena samatha kuzindikira zamankhwala obwera kwa hypoglycemia kapena omwe zochitika za hypoglycemia nthawi zambiri zimawonedwa. Muzochitika izi, ndikofunikira kuyesa kuyendetsa koyenera.

Kutulutsa Fomu / Mlingo: Njira yothetsera kulowetsedwa kwamkati ndi panjira, 100 IU / ml. Kulongedza:

3 ml ya mankhwala pa cartridge. Makatiriji asanu pachimake. Chithuza chimodzi pamodzi ndi malangizo ogwiritsira ntchito pakatoni.

3 ml ya mankhwalawa mu cartridge wophatikizidwa ndi cholembera cha syringe ya QuickPen ™.Ma syringe asanu a QuickPen ™ aliyense, limodzi ndi malangizo ogwiritsira ntchito ndi malangizo a QuickPEN ™ Syringe cholembera ogwiritsira ntchito pabokosi la makatoni.

Sungani mufiriji kutentha kwa 2-8 ° C.

Mankhwala omwe agwiritsidwa ntchito mu cholembera / syringe Iyenera kusungidwa kutentha kwambiri osati 30 ° C, osapitirira masiku 28.

Kuteteza ku dzuwa mwachindunji ndi kutentha. Osalola kuzizira.

Pewani kufikira ana. 10/27/2015 Malangizo ofotokoza

Malangizo ogwiritsira ntchito:

Humalog ndi njira yochizira matenda ashuga.

Mankhwala

Humalog ndi chithunzi chopangidwa cha insulin yofupikitsa anthu. Imayendetsa kagayidwe ka glucose m'thupi, kuchepetsa magazi ake. Poterepa, kuchuluka kwa glucose mu mawonekedwe a glycogen kumadziunjikira minofu ndi chiwindi. Insulin Humalog imathandizira kapangidwe kazinthu zomanga thupi, kumwa ma amino acid, kuchepetsa kuchepa kwa glycogen kupita ku glucose, ndikuchepetsa kupanga kwa glucose kuchokera m'mafuta ndi mapuloteni.

Insulin yofupikitsa nthawi zambiri imaphatikizidwa ndi basal yopewa magazi. Kutalika kwa zochita za Humalog kumasiyana pakati pa odwala osiyanasiyana ndipo zimatengera zinthu zambiri.

Pankhani ya matenda a shuga 2, pamene wodwala amalandira mapiritsi amodzi munthawi yomweyo mapiritsi ndi insulin, kuwongolera shuga kumakhala wodalirika kwambiri. Izi zimawonetsedwa kuchepa kwa mphamvu ya hemoglobin ya glycated panthawi yowunika chithandizo. Humalog imachepetsa pafupipafupi kuchepetsa shuga m'magazi usiku. Mkhalidwe wa chiwindi ndi impso za wodwalayo sizikhudza kagayidwe ka mankhwala.

Malinga ndi malangizowo, Humalog imatengedwa mwachangu ndipo imayamba kugwira ntchito mphindi 15 pambuyo pa kuwongolera, motero imatha kutumizidwa mphindi 15 asanadye, mosiyana ndi ma insulin ena achidule, omwe amatengedwa mphindi 30 mpaka 45. Kutalika kwake ndi kufupikirapo kuposa insulin wamba yamunthu, ndipo ndi maola 2 - 5 okha.

Malangizo ogwiritsira ntchito Humalog

Mankhwalawa amaperekedwa pang'onopang'ono jekeseni kapena pampu ya insulin musanadye. Masamba obayira ndi mapewa, ntchafu, pamimba kapena matako. Muyenera kuwasinthanitsa kuti m'malo amodzi jakisoni asabwerezedwe kawiri m'mwezi umodzi, izi zitha kupewa kuchepa kwa minyewa. Tiyenera kuyesetsa kuti tisalowe m'mitsempha yamagazi. Osapaka jakisoni pamalo atabayidwa kuti mupeze bwino mankhwalawa.

Muzochitika zofunikira, Humalog insulin imatha kuperekedwa kudzera mu minyewa yothandizira (opaleshoni, ketoacidosis, etc.). Pamaso jakisoni, onetsetsani kuti yankho limawotha kutentha kwa chipinda.

Mlingo wa Humalog ndiwothandiza pa wodwala aliyense ndipo amawerengedwa ndi dokotala. Osasakaniza ma insulini osiyanasiyana mu cholembera.

Humalog siigwira ntchito bwino mukamamwa pamodzi ndi glucocorticoids, njira zakulera zam'kamwa, mankhwala a chithokomiro, komanso nicotinic acid. Ethanol, salicylates, ACE zoletsa, beta-blockers amawonjezera mphamvu ya insulin.

Pa nthawi yoyembekezera komanso mkaka wa m'mawere, kayendetsedwe ka insulin kameneka ndi kovomerezeka, koma kuwunika kwambiri misempha ya magazi ndikofunikira. Mukamayamwitsa, kukumbukira momwe mankhwalawa nthawi zambiri amafunikira chifukwa chofunikira kwambiri cha insulini. Mankhwala amavomerezedwa kuti azigwiritsidwa ntchito mwa ana.

Zotsatira zoyipa

Nthawi zina wokhala ndi mankhwala osokoneza bongo kapena mawonekedwe amodzi amomwe thupi limapangira, Humalog imatha kupangitsa kuchepa kwa shuga wamagazi - hypoglycemia.

Nthawi zina, pali matupi awo sagwirizana ndi mankhwalawa mu mawonekedwe a totupa, redness, kuyabwa kwa khungu, m'malo ovuta - angioedema.

Pomwe jakisoni, kufalikira kwa gawo lochepa wamafuta, lipodystrophy, zitha kudziwika.

Mlingo

Yankho la iv and sc management

insulin lispro 100 IU

Othandizira: glycerol (glycerin) - 16 mg, metacresol - 3,15 mg, zinc oxide (q.s.pazambiri za Zn2 + 0.0197 μg), sodium hydrogen phosphate heptahydrate - 1,88 mg, hydrochloric acid solution 10% ndi / kapena sodium hydroxide solution 10% - q.s. mpaka pH 7.0-8.0, madzi d / i - q.s. mpaka 1 ml.

Mikhalidwe yapadera

Kusamutsa wodwala kupita ku mtundu wina kapena mtundu wa insulin kuyenera kuchitika moyang'aniridwa ndi achipatala. Kusintha kwa zochitika, mtundu (wopanga), mtundu (mwachitsanzo, Wokhazikika, NPH, Tepi), mitundu (nyama, anthu, ma insulin analogue) ndi / kapena njira yopanga (DNA recombinant insulin kapena insulini yachikhalidwe) ingafunike kusintha kwa mlingo.

Mikhalidwe yomwe zizindikiro zoyambirira za hypoglycemia zitha kukhala zosakhudzika komanso zochepa zomwe zimaphatikizidwa zimaphatikizapo kukhalapo kwa matenda a shuga, kulimbitsa kwambiri insulin, matenda amanjenje m'matenda a shuga, kapena mankhwala, monga beta-blockers.

Odwala omwe ali ndi vuto la hypoglycemic atasamutsidwa kuchokera ku insulin yochokera ku nyama kupita ku insulin yaumunthu, zizindikiro zoyambirira za hypoglycemia zitha kutchulidwa pang'ono kapena zosiyana ndi zomwe adakumana nazo kale ndi insulin. Hypoglycemic yosasinthika kapena ma hyperglycemic zomwe zimachitika zimatha kuyambitsa chikumbumtima, chikomokere, kapena kufa.

Mlingo wosakwanira kapena kutha kwa mankhwalawo, makamaka ndi matenda a shuga a shuga, amatha kutsegula ndi hyperglycemia ndi matenda ashuga a ketoacidosis, mikhalidwe yomwe ikhoza kukhala pangozi kwa wodwalayo.

Kufunika kwa insulini kumatha kuchepa kwa odwala omwe amalephera kupweteka kwa impso, komanso kwa odwala omwe ali ndi vuto la chiwindi chifukwa cha kuchepa kwa njira ya gluconeogeneis ndi insulin metabolism. Komabe, mwa odwala omwe ali ndi vuto losatha la chiwindi, kukana kwa insulini kungayambitse kuchuluka kwa insulin.

Kufunika kwa insulin kumatha kuwonjezeka ndi matenda opatsirana, kupsinjika kwamalingaliro, ndikuwonjezereka kwa kuchuluka kwa chakudya chamagulu muzakudya.

Kusintha kwa mlingo kumafunikanso ngati wodwala akuchulukitsa kapena kusintha kwachilendo kwa zakudya. Kuchita masewera olimbitsa thupi mukangomaliza kudya kumawonjezera chiopsezo cha hypoglycemia. Zotsatira za pharmacodynamics za insulin analogi zomwe zimagwira mwachangu ndikuti ngati hypoglycemia imayamba, ndiye kuti imatha kupanga jekeseni m'mbuyomu kuposa kubayidwa insulin yamunthu.

Wodwalayo ayenera kuchenjezedwa kuti ngati dokotala atayambitsa kukonzekera kwa insulin ndi kuchuluka kwa 40 IU / ml mu vial, ndiye kuti insulini sayenera kutengedwa kuchokera ku cartridge ndi insulin ya 100 IU / ml ndi syringe ya jekeseni wa insulin wochita ndi 40 IU / ml.

Ngati ndi kotheka, imwani mankhwala ena nthawi yomweyo ndi mankhwalawo

Shuga mellitus mwa akulu ndi ana, omwe amafunikira chithandizo cha insulin kuti akhalebe ndi shuga.

Contraindication

Hypersensitivity pamagawo a mankhwala.

Mitengo ya Humalog m'mizinda inanso

Gulani Humalog, Humalog ku St. Petersburg, Humalog ku Novosibirsk,

Ultrashort insulin Humalog: phunzirani zonse zomwe mukufuna. Pansipa mupeza malangizo ogwiritsira ntchito olembedwa m'chinenerochi. Werengani mayankho a mafunso:

Ultrashort Insulin Humalog: Nkhani Yatsatanetsatane

Tsamba lawebusayiti silikulimbikitsa kugula mapiritsi a insulin ndi matenda a shuga kuchokera m'manja, malinga ndi malonda. Kugula kuchokera kwa anthu, mukuyenera kulandira mankhwala osagwira ntchito, osagwira ntchito. Akasungidwa, Humalog nthawi zambiri imakhala yowonekera bwino. Mwa mawonekedwe a insulini ndizosatheka kuweruza mtundu wake. Chifukwa chake, muyenera kugula kokha mumafakitale odziwika, odziwika bwino, omwe amatsatira malamulo osungira.

Kutulutsa mawonekedwe ndi kapangidwe kake

Insulin Humalog imapezeka monga njira yopanda utoto ya jakisoni. Ntchito mankhwalawa subcutaneous komanso mtsempha wamagazi. Chofunikira chachikulu pa mankhwalawa ndi Lizpro insulin, chomwe ndi chosiyanitsa ndi kusintha kwa mapangidwe a amino acid mu insulin B.

Mankhwalawa amagulitsidwa m'mak cartridge atatu. Pofuna kukhazikitsa bwino, zolembera za syringe zimagwiritsidwa ntchito. Pogulitsa mutha kupeza mitundu ya mankhwalawa: Humalog Remix 25 ndi Humalog Remix 50. Njira yoyamba ili ndi 25% Lizpro insulin (yochepa) ndi 75% Lizpro insulin kuyimitsidwa (nthawi yayitali), mtundu wachiwiri wa mahomoni uli ndi zinthu zonse zofanana.

Kuphatikizika kwa mankhwalawa kumaphatikizapo zina zowonjezera: glycerol, metacresol, zinc oxide, sodium hydrogen phosphate heptahydrate, hydrochloric acid (sodium hydroxide solution) ndi madzi.

Mfundo yogwira ntchito

Insulin yokhala ndi yochepa-pang'onopang'ono imayamba kugwira ntchito thupi isanakhale ndi nthawi yokwanira ndikuyamwa chakudya chomwe chalandira mgulu la glucose. Mankhwala oterewa amagwiritsidwa ntchito nthawi zambiri ngati pakufunika kuti magazi a shuga azikhazikika, pomwe kuthamanga kwake sikunayambitse zovuta. Komabe, pali zochitika zina pamene insulin yochepa kwambiri imafunikira ngakhale odwala omwe amatsatira malangizo a dokotala ndipo amakhala ndi moyo wathanzi. Mwachitsanzo, ndikudumphalumpha m'magazi a glucose panthawi yovuta.

Mukamagwiritsa ntchito insulin ya ultrashort, ndikofunikira kukumbukira kuti ili ndi mphamvu kangapo kuposa fanizo la mahomoni osakhalitsa. 1 unit ya Humalog imatha kuchepetsa shuga m'magazi mara 2,5 mwachangu kuposa 1 unit ya insulin yochepa. Komabe, kuti mankhwala azamankhwala azitha kuyenda bwino, ndikofunikira kusankha mlingo woyenera.

Ubwino ndi zoyipa

Mtundu uliwonse wa insulin uli ndi zabwino zake komanso zopweteka zake. Kuchita bwino kwa mankhwalawa kumawunikidwa ndi kuchuluka kwa momwe amathandizira pamagazi ndi kuchuluka kwa kuchepa kwa insulin. Chiwonetserocho chimadziwika ndi nsonga yakuthwa. Imayamba kugwira ntchito mkati mwa mphindi 15 mutamwa. Chifukwa chake, tikulimbikitsidwa kulowa mphindi 15-20 musanadye.

Kuthamanga kwa mankhwalawa kumawerengedwa kuti ndi chimodzi mwamaubwino ake. Chizindikirochi ndichofunikira kwambiri kwa iwo omwe sangathe kubayira kawiri kawiri. Kutalika ndi mphamvu ya zochita zimatengera malo a mankhwalawa, thanzi, mikhalidwe ya munthu payekha. Insulin Humalog ili ndi mayamwidwe abwino. Kuzindikira kwake kwakukulu kumadziwika kuti ndi mphindi 30-60 pambuyo pa kutsata.

Mwa zina zabwino za mankhwalawa titha kudziwa:

• kuthekera kuchepetsa kwambiri ziwonetsero za nocturnal glycemia,
• kuthekera kopanga minofu powonjezera zomwe zili ndi mafuta ac acid ndikupangitsa kuphatikiza mapuloteni ena,
• mathamangitsidwe a ntchito ma amino acid.

Choyipa chachikulu cha Humalog ndi kusakhazikika kwake. Kuti mupeze ngati mphamvu ya mankhwalawa m'thupi ikupitilira kapena yatha kale, ndikofunikira kutenga miyezo ndi glucometer. Izi sizoyenera nthawi zonse.

Malamulo oyambira

Insulin Humalog imatha kuperekedwa m'njira ziwiri: subcutaneous and intrarally. Makina a subcutaneous ali ngati mawonekedwe a jakisoni, kulowetsedwa, kapena pampu ya insulin. Magulu olowa mkati amangokhala ngati njira yomaliza. Kuti muchite izi, mutha kugwiritsa ntchito gawo la m'chiuno, mapewa, pamimba ndi matako. Sitikulimbikitsidwa kupereka mankhwalawo pamalo omwewo.

Kuti mupeze insulin bwino, muyenera kutsatira malamulo ena.

1. Pamaso pa makonzedwe, onetsetsani kuti yankho likuwonekera poyera, osayera, zodetsa nkhawa.
2. Sambani m'manja ndikuwona malo oyambira. Chitani ndi antiseptic.
3. Chotsani kapu yoteteza ku singano. Kokani kapena kutsina khungu mu crease ndikusintha.
4. Ikani singano molingana ndi malangizo ogwiritsa ntchito ndikudina batani.
5. Chotsani singano.Kanikizani tsamba la jekesayo pang'ono. Osachipaka kapena kulikakamiza.
6. Tsekani singano yomwe imagwiritsidwa ntchito ndi kapu. Tulutsani ndikuchotsa.
7. Tsekani cholembera ndi cholembera ndikuchiyika mosungira.

Ngati mukugwiritsa ntchito Humalog Insulin kwa nthawi yoyamba, werengani mosamala buku la ogwiritsa ntchito musanayende. Ngati muli ndi mafunso, kambiranani ndi dokotala.

Kodi zingakwanitse bwanji?

Humalog mwachangu kuposa mankhwala ena amatha kupangitsa kuti shuga azikhala kwambiri. Chifukwa chake, ndibwino kukhala nanu pokhapokha pachitika ngozi. Komabe, ochepa omwe ali ndi matenda ashuga omwe akufuna kugwiritsa ntchito onse aifupi ndi a insulin. Ngati muthana ndi kagayidwe kakang'ono ka shuga wanu wamafuta ochepa, mungathe kudutsa ndi mankhwala osakhalitsa.

Kodi jakisoni aliyense amatalika bwanji?

Jekeseni aliyense wa mankhwala a Humalog amatha pafupifupi maola anayi. Anthu odwala matenda ashuga omwe amatsata amafunika Mlingo wambiri wa insulin. Nthawi zambiri imayenera kuchepetsedwa kuti ipange jekeseni woyenera wa mankhwala osakwana 0,5-1. Humalog imatha kuchepetsedwa osati kwa ana omwe ali ndi matenda a shuga 1, komanso odwala akuluakulu. Chifukwa ndi mankhwala amphamvu kwambiri. Mukamagwiritsa ntchito mankhwala ochepa, insulin imasiya kugwira ntchito mwachangu kuposa momwe amafunidwira. Mwina jakisoni amatha kumapeto kwa maola awiri ndi awiri ndi awiri.

Pakapita jakisoni iliyonse ya kukonzekera kwa ultrashort, muyezetse magazi osachepera maola atatu pambuyo pake. Chifukwa kufikira nthawi ino, mlingo wa insulin wolandirira ulibe nthawi kuti uwonetse mphamvu yake yonse. Monga lamulo, odwala matenda ashuga amapereka jakisoni wa insulin yofulumira, idyani, kenako kuyeza shuga kale chakudya chotsatira. Pokhapokha ngati wodwala akumva. Zikatero, muyenera kudziwa nthawi yomweyo kuchuluka kwa shuga m'magazi ndipo ngati kuli koyenera, chitanipo kanthu.

Kodi pali kusiyana kotani pakati pa Humalog ndi Humalog Remix?

Prostamine Hagedorn (NPH) yosalowerera ndale, yomwe imachepetsa zochita za insulin, yawonjezeredwa ku Humalog Remix 25 ndi 50. Mitundu ya insulin iyi imasiyana ndi zomwe zili mu NPH. Mowonjezereka mankhwala, kumawonjezera zochita za jakisoni. Mankhwalawa ndi otchuka chifukwa amatha kuchepetsa kuchuluka kwa jakisoni tsiku ndi tsiku, kuchepetsa njira ya insulin. Komabe, sangapereke magazi moyenera. Chifukwa chake, tsamba lawebusayiti silimbikitsa kugwiritsa ntchito kwawo.

Werengani za kupewa ndi kuchiza mavuto:

Ndi insulin iti yomwe ili bwino: Humalog kapena NovoRapid?

Pangakhale palibe chidziwitso cholondola choyankha funso ili, lomwe nthawi zambiri limafunsidwa ndi odwala. Chifukwa mitundu yambiri ya insulini imakhudza aliyense wodwala matenda ashuga payekhapayekha. Monga Humalog, ali ndi mafani ambiri. Monga lamulo, odwala amapaka jakisoni mankhwala omwe amapatsidwa kwaulere.

Ziwengo zimakakamiza ena kuti asinthe mtundu wina wa insulin kupita ku wina. Tikubwerezanso kuti, ngati tikuwonetsetsa kuti tikuyenda mwachangu musanadye, ndibwino kugwiritsa ntchito mankhwala achidule, mwachitsanzo, m'malo mwa ultrashort Humalog, NovoRapid kapena Apidra. Ngati mukufuna kusankha mitundu yoyenera ya insulin yowonjezera komanso yachangu, ndiye kuti simungathe kuchita popanda kuyesa komanso zolakwika.

Mndandanda wa insulin Humalog (lispro) - awa ndi mankhwala osokoneza bongo komanso. Kapangidwe ka mamolekyulu awo ndiosiyana, koma pochita nawo zilibe kanthu. akuti Humalog amachita mwachangu komanso mwamphamvu kuposa anzawo. Komabe, si odwala onse omwe amatsimikizira izi. Pamabwalo a odwala matenda ashuga olankhula Chirasha, mutha kupeza mawu otsutsa.

Odwala omwe ali ndi matenda amtundu wa 1 ndi mtundu wa 2 omwe amawonera angayesere kusintha insulin lispro ndi mankhwala osakhalitsa. Mwachitsanzo, pa. Pamwambapo zalembedwa mwatsatanetsatane chifukwa chake izi ndizoyenera kuchita. Komanso, insulin yochepa ndiyotsika mtengo. Chifukwa adalowa m'msika zaka zambiri m'mbuyomu.

Insulin yaifupi yaumunthu imayamba ntchito yake mphindi 30-45 pambuyo poti idalowetsedwe m'thupi.Pali mitundu yamakono ya insulin yochepa kwambiri yomwe imagwira ntchito pambuyo pa mphindi 10. Izi zikuphatikiza mitundu yapamwamba ya insulin yaumunthu: Apidra, Novo-Rapid ndi Humalog. Izi zofananira ndi insulin yachilengedwe, chifukwa cha njira yabwino kwambiri, zimatha kuchepetsa kuchuluka kwa shuga m'magazi mwadzidzidzi kulowa mkati mwa thupi la wodwala ndi matenda ashuga.

Kodi insulin yokumba ndi chiyani?

Insulin yongopangidwira anaipanga mwapadera kuti ithetse msuzi wa shuga wambiri chifukwa cha kuphwanya zakudya zolimba za munthu wovutika. Monga momwe masewera amasonyezera, sizingatheke kuchita izo 100 peresenti, chifukwa mukamagwiritsa ntchito zakudya zoletsedwa kwa odwala matenda ashuga, shuga wamagazi amatha kukwera kwambiri.

Ngakhale pali mitundu yosiyanasiyana ya shuga, zakudya zamagulu ochepa zimatha kunyalanyazidwa, chifukwa kuchuluka kwa shuga m'magazi kumakhudza chithunzi chonse cha matendawa.

Ultrashort insulini imagwiritsidwa ntchito kuti muchepetse shuga mwachangu, komanso nthawi zina musanadye. Izi ndizofunikira ngati wodwala matenda ashuga amadzuka shuga atangodya.

Dokotalayo amapereka mankhwala amtundu wa 1 kapena odwala matenda ashuga a 2 omwe ayenera kudziletsa kwathunthu pamagazi a shuga. Njirayi iyenera kuchitika kwa sabata limodzi pokhapokha panthawiyi ikatha kupanga lingaliro la mtundu wa insulini yomwe uyenera kubayidwa, mlingo wake komanso nthawi yanji. Ndikosatheka kupangira chiwembu chaponseponse, chifukwa chilichonse chimakhala chosiyana ndi payekha.

Kodi mankhwala a insulin amagwira ntchito bwanji?

Ngati timalankhula za mtundu wa insulin waifupi kwambiri, ndiye kuti umagwira ntchito kale kwambiri kuposa momwe wodwalayo adayamba kusintha protein kukhala glucose wamagazi. Pachifukwa ichi, anthu omwe amatsata zakudya zamafuta ochepa mokhazikika komanso moyenera amatha kugwiritsa ntchito insulin yochepa asanadye.

Iyenera kulowetsedwa m'thupi pafupi ndi mphindi 45 chakudya chisanafike. Nthawiyo sinafotokozedwe ndendende, chifukwa wodwala aliyense ayenera, kudzera poyeserera ndi kulakwitsa, apeze nthawi yoyenera ya jakisoni. Insulin yaumunthu imagwira ntchito kwa maola 5, chifukwa ndi munthawi imeneyi pomwe zakudya zonse zimayamwa ndipo glucose amalowa m'magazi.

Ponena za insulin yosinthidwa, ndikofunikira pakukakamiza kuti muchepetse shuga mwachangu kwa wodwala. Izi ndizofunikira kwambiri, chifukwa pamlingo wake wokwera kwambiri pamakhala zovuta zina za matenda ashuga ndi zizindikiro zake. Pazifukwa izi, ndikosayenera kugwiritsa ntchito insulin wamba.

Tanthauzirani mfundo zina:

1. Kwa iwo omwe ali ndi matenda a shuga a 2 ofiira ndipo shuga m'magazi awo amatha kuchepa palokha, palibe chifukwa chobayira insulin kuti muchepetse shuga.
2. Ngakhale mutatsatira malangizo a dokotala okhudzana ndi kuchuluka kwa chakudya chamafuta, ma insulin analogue yaumunthu imatha kukhala yothandiza. Ngati shuga adalumphira mwadzidzidzi, ndiye kuti insulin yochepa kwambiri imachepetsa kangapo mwachangu. Izi zikuchokera pamenepa kuti zovuta za matenda a shuga sizingatheke kuyambitsa kudwala kwawo.
3. Nthawi zina, simungatsatire kudikirira mphindi 45 musanadye, komabe, izi ndizokhazo.

Nthawi zonse muyenera kukumbukira kuti ma insulin a ultrashort ali ndi mphamvu zambiri kuposa amfupi. Kuyankhula manambala, 1 unit ya Humalog insulin ikhoza kuchepetsa kuchuluka kwa glucose 2,5 mofulumira kuposa 1 unit ya insulin yokhazikika.

Mitundu ina imapereka insulin yocheperako "Apidra" ndi "Novo-Rapid" - imathamanga nthawi 1.5. Manambalawa sangatengedwe ngati amtheradi, chifukwa chiwerengerochi chikuwonetsa.Kudziwa molondola izi zimatheka pokhapokha pochita chilichonse. Zomwezo zimagwiranso ntchito pa Mlingo wa ultrashort insulin. Itha kutsika kwambiri poyerekeza ndi insulin yokhazikika.

Ngati tikufanizira "Humalog", "Apidra" ndi "Novo-Rapid", ndiye mankhwala oyamba omwe amapambana mwachangu pa zisanu.

Ubwino ndi kuipa kwa insulin

Kafukufuku wambiri adawonetsa kuti insulin yamtundu uliwonse imatha kukhala ndi zabwino komanso zovuta zazikulu.

Ngati tizingolankhula za insulin yayifupi yaumunthu, ndiye kuti kuchuluka kwake kwa magazi a munthu wodwala matenda ashuga kumatha pambuyo pojambulira ndi njira ya ultrashort, koma nthawi yomweyo, msambo wake woponderezedwa umatsika kwambiri, ndipo sungasinthe.

Chifukwa chakuti Humalog ili ndi nsonga zakuthwa, ndizovuta kwambiri kulosera zenizeni zenizeni za chakudya zomwe zimatha kuwonongedwa kotero kuti kuchuluka kwa shuga m'magazi a wodwalayo kumakhalabe kwabwinobwino. Zotsatira zabwino za insulin yochepa zimathandizira kuyamwa kwa zinthu zofunika kwambiri kuchokera ku chakudya, malinga ndi kuyang'aniridwa kwathunthu kwa zakudya zapadera kuti muchepetse shuga.

Ngati tikuwona nkhani iyi mbali inayo, ndiye kuti nthawi iliyonse musanadye zimakhala zovuta kudikira mphindi 45 kuti insulini yayifupi iyambe kuchitapo kanthu. Ngati vutoli silikumbukiridwa, ndiye kuti shuga m'magazi limakula mofulumira kuposa momwe chinthu chovulalacho chitha kugwira ntchito.

Homoni wopanga amatha kuchepetsa insulin pambuyo pa mphindi 10-15 atabayidwa. Izi, ndizosavuta, makamaka ngati chakudyacho sichinatengedwe malinga ndi dongosolo linalake.

M'moyo weniweni, zimapezeka kuti insulin yochepa yaumunthu imagwira ntchito molimba kwambiri kuposa ultrashort. Zomalizirazo zimakhala zopanda chidwi, ngakhale zitagwiritsidwa ntchito muyezo waung'ono kwambiri, osanenapo za milanduyo pamene odwala amadzipaka okha ndi mulingo wambiri wa mankhwala.

Tiyeneranso kukumbukira kuti insulin yabwino kwambiri imakhala yamphamvu kangapo kuposa munthu. Mwachitsanzo, 1% ya Humaloga ndi gawo limodzi mwa magawo anayi a insulini yochepa, ndipo mlingo umodzi wa Apidra ndi Novo-Rapida ndi pafupifupi 2/3. Komabe, ndikofunikira kudziwa kuti ziwerengerozi ndizongoyerekeza, ndipo kutsitsimutsa kwawo kumatheka pongoyesa.

Pali odwala ena omwe ali ndi matenda ashuga omwe amakhala ndi insulin yochepa kwa nthawi yayitali. Nthawi imeneyi imatha kukhala pafupifupi mphindi 60 mpaka maola 1.5. Zikatero, zimakhala zovuta kwambiri kudya chakudya motonthoza. Kwa odwala oterewa ndikulimbikitsidwa kugwiritsa ntchito insulin yofulumira kwambiri ya ultrashort Humalog, komabe, milandu yotereyi imakhala yachilendo.

Mlingo ndi makonzedwe

Mlingo wa Humalog® umatsimikiziridwa ndi dokotala aliyense payekha, kutengera kuchuluka kwa shuga m'magazi. Ndondomeko ya insulin makonzedwe ali payekha.

Humalog® imatha kuperekedweratu chakudya chisanafike. Ngati ndi kotheka, Humalog® imatha kuperekedwanso pambuyo chakudya.

Kutentha kwa mankhwala omwe amaperekedwa kuyenera kukhala kutentha kwambiri.

Humalog® iyenera kutumikiridwa ngati jakisoni wofunda kapena ngati kulowetsedwa kofikira pogwiritsa ntchito pampu ya insulin. Ngati ndi kotheka (ketoacidosis, matenda owopsa, nthawi pakati pa ntchito kapena nthawi yothandizira), kukonzekera kwa Humalog® amathanso kuthandizira.

Subcutaneally ayenera jekeseni phewa, ntchafu, matako kapena m'mimba. Masamba a jakisoni amayenera kusinthidwa kuti malo omwewo asagwiritsidwerenso kuposa nthawi 1 pamwezi.

Ndi subcutaneous makonzedwe a Humalog®, chisamaliro chiyenera kutengedwa kuti mankhwalawo asalowe mumtsempha wamagazi. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa.Wodwala ayenera kuphunzitsidwa njira yolondola ya jakisoni.

Malangizo a kuperekera mankhwala Humalog®
Kukonzekera mawu oyamba
Njira yothetsera kukonzekera kwa Humalog® iyenera kukhala yowonekera komanso yopanda utoto. Musagwiritse ntchito yankho la Humalog® ngati litakhala lamtambo, lopindika, lopanda utoto, kapena tinthu tating'onoting'ono tadziwika.

Mukakhazikitsa cartridge mu syringe cholembera, ndikukhala ndi singano ndikulowetsa insulin, tsatirani malangizo a wopanga omwe akuphatikizidwa ndi cholembera chilichonse.

Dose management
1. Sambani m'manja.
2. Sankhani tsamba la jakisoni.
3. Konzani khungu lanu jakisoni monga momwe dokotala wanenera.
4. Chotsani chophimba chakunja kuchokera mu singano.
5. Tsekani khungu.
6. Ikani singano pang'onopang'ono ndikuchita jakisoni mogwirizana ndi malangizo ogwiritsa ntchito cholembera.
7. Chotsani singano ndikufinya pang'onopang'ono malo opaka jakisoni ndi swab ya thonje kwa masekondi angapo. Osatupa malo a jakisoni.
8. Pogwiritsa ntchito singano yakunja, vula singano ndikuitaya.
9. Ikani chipewa pa cholembera.

Za kukonzekera kwa Humalog® mu cholembera cha syringe ya QuickPen ™.
Musanapereke insulin, chonde werengani Malangizo a QuickPen ™ Syringe pen Institions for Use.

Insulinven insulin
Kubayidwa kwapakati pa kukonzekera kwa Humalog® kuyenera kuchitika molingana ndi chizolowezi chachipatala cha jakisoni wamkati, mwachitsanzo, kulowetsedwa kwa bolus kapena kugwiritsa ntchito kulowetsedwa. Poterepa, nthawi zambiri ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi.

Makina a kulowetsedwa okhala ndi zozungulira kuyambira 0,1 IU / ml mpaka 1,0 IU / ml insulin lispro mu 0,9% sodium chloride solution kapena 5% dextrose solution amakhala okhazikika firiji kwa maola 48.

Subcutaneous insulin kulowetsedwa ndi insulin pampu
Potengera kukonzekera kwa Humalog ®, ma pump angagwiritsidwe ntchito - machitidwe opitiliza kukhazikitsa insulin ndi chizindikiro cha CE. Musanagwiritse inshuwaransi ya lyspro, onetsetsani kuti pampu ina ndiyabwino. Muyenera kutsatira mosamalitsa malangizo omwe abwera ndi pampu. Gwiritsani ntchito posungira ndi patheter yabwino pampu. The kulowetsedwa anayenera asinthidwe malinga ndi malangizo omwe amaperekedwa ndi kulowetsedwa. Ngati vuto la hypoglycemic litayamba, kulowetsaku kumayimitsidwa mpaka gawo litatsimikiza. Ngati shuga wambiri m'magazi adziwika, ndikofunikira kudziwitsa dokotala za izi ndikupereka kuchepa kapena kufooka kwa kulowetsedwa kwa insulin. Kuperewera bwino kwa pampu kapena kufalikira mu dongosolo la kulowetsedwa kungapangitse kukwera kwamphamvu kwa glucose. Ngati mukukayikira kuti ndikuphwanya kupereka kwa insulin, muyenera kutsatira malangizowo ndipo ngati kuli koyenera dziwitsani adokotala. Mukamagwiritsa ntchito pampu, kukonzekera kwa Humalog® sikuyenera kusakanikirana ndi ma insulini ena.

Zotsatira zoyipa

Hypoglycemia ndiye chovuta kwambiri pakachitika odwala omwe ali ndi matenda a shuga. Hypoglycemia yayikulu imatha kutha mphamvu ya chikumbumtima (hypoglycemic chikomokere), ndipo, mwatsatanetsatane, kufa.

Odwala amatha kukumana ndi zovuta zam'deralo mu mawonekedwe ofiira, kutupa, kapena kuyabwa pamalowo. Nthawi zambiri, zizindikirozi zimatha patatha masiku angapo kapena milungu. Nthawi zina, izi zimachitika chifukwa cha zifukwa zosakhudzana ndi insulin, mwachitsanzo, kupsa mtima pakhungu ndi wothandizira kuyeretsa kapena jakisoni wosayenera.

Nthawi zambiri, thupi siligwirizana zimayambira pomwe kuyabwa mthupi, ming'oma, angioedema, kutentha thupi, kufupika, kutsika magazi, tachycardia, ndi thukuta kumachitika. Milandu ingapo yamomwe thupi limagwirira ntchito ikhoza kukhala yowopsa pamoyo.

Lipodystrophy imatha kupezeka pamalo a jakisoni.

Mauthenga wamba:
Milandu ya chitukuko cha edema yadziwika, makamaka ndi kufalikira kwamisempha yamwazi motsutsana ndi maziko a insulini yolimbana ndi vuto loyambirira la glycemic.

Kuchita ndi mankhwala ena

Kuopsa kwa zotsatira za hypoglycemic kumachepetsedwa ngati ntchito limodzi ndi mankhwalawa: kulera kwapakamwa, glucocorticosteroids, mahomoni a chithokomiro, danazol, beta2-adrenergic agonists (mwachitsanzo, ribodrin. phenothiazine.

Kuopsa kwa zotsatira za hypoglycemic kumawonjezereka pamodzi ndi mankhwala omwe amaphatikizidwa: beta-blockers, ethanol ndi ethanol-mankhwala, anabolic steroids, fenfluramine. guanethidine, tetracyclines, mankhwala a hypoglycemic a m'kamwa, salicylates (mwachitsanzo acetylsalicylic acid), mankhwala a sulfonamide. antidepressants (monoamine oxidase inhibitors, serotonin reuptake inhibitors), angiotensin kutembenuza enzyme inhibitors (Captopril, enapril), octreotide, angiotensin II receptor antagonists.

Ngati mukufunika kugwiritsa ntchito mankhwala ena, kuwonjezera pa insulin, funsani dokotala.

Malangizo apadera

Kusamutsa wodwala kupita ku mtundu wina kapena kukonzekera insulin kuyenera kuchitika moyang'aniridwa ndi achipatala. Kusintha kwa zochitika, mtundu (wopanga), mtundu (Wokhazikika, NPH, ndi zina), mitundu (nyama, munthu, analog ya insulin ya anthu) ndi / kapena njira yopanga (DNA recombinant insulin kapena insulini yachikhalidwe) chitha kubweretsa kufunika kwa kusintha kwa mlingo.

Odwala omwe ali ndi vuto la hypoglycemic atasamutsidwa kuchokera ku insulin yochokera ku nyama kupita ku insulin yaumunthu, zizindikiro zoyambirira za hypoglycemia zitha kutchulidwa pang'ono kapena zosiyana ndi zomwe adakumana nazo kale ndi insulin. Machitidwe osasinthika a hypo- ndi hyperglycemic angapangitse kuti musakhale ndi chikumbumtima, chikomokere, kapena kufa.

Tiyenera kukumbukira kuti pharmacodynamics ya analogues ya insulin yogwira ntchito mwachangu ya anthu ndikuti ngati hypoglycemia imayamba, itha kupanga pambuyo pobayira wa insulin analogue yomwe imagwira mwachangu kale kuposa momwe insulin ya anthu imagwiritsidwa ntchito.

Kwa odwala omwe amalandira ma insulin achidule komanso oyambira, amafunika kusankha kuchuluka kwa ma insulin onse kuti akwaniritse kuchuluka kwa shuga m'magazi masana, makamaka usiku kapena pamimba yopanda kanthu.

Zizindikiro zakutsogolo kwa hypoglycemia zimatha kusintha ndikusatchulidwa pang'ono ndi njira yayitali ya matenda a shuga, matenda ashuga a m'mimba kapena chithandizo cha mankhwala monga beta-blockers.

Mlingo wosakwanira kapena kusiya kulandira chithandizo, makamaka kwa odwala omwe ali ndi matenda a shuga 1, angayambitse matenda a hyperglycemia ndi matenda ashuga - matenda omwe angawononge odwala.

Kufunika kwa insulin kumatha kuchepa ngati kulephera kwa impso, komanso kwa odwala omwe ali ndi vuto la kuchepa kwa chiwindi chifukwa cha kuchepa kwa njira ya gluconeogeneis ndi insulin metabolism. Komabe, mwa odwala omwe ali ndi vuto losatha la chiwindi, kukana kwa insulini kungayambitse kuchuluka kwa insulin.

Kufunika kwa insulin kumatha kuwonjezeka ndi matenda ena kapena kupsinjika mtima.

Malangizo a insulin ayenera kuchuluka ngati odwala akuwonjezera zolimbitsa thupi kapena akusintha zakudya zamagulu. Kuchita masewera olimbitsa thupi kumatha kuyambitsa chiwopsezo cha hypoglycemia.

Mukamagwiritsa ntchito insulin pokonzekera limodzi ndi mankhwala a gulu la thiazolidinedione, chiopsezo chotenga matenda a edema ndi matenda a mtima omwe amalephera chikuwonjezereka, makamaka kwa odwala omwe ali ndi matenda amtima komanso kupezeka kwa zinthu zomwe zingayambitse matenda osalephera a mtima.

Kugwiritsa ntchito Humalog® kwa ana m'malo mwa insulin yaumunthu yosungunuka ndikofunikira panthawi ngati kuli koyenera kuyambitsa mwachangu insulin (mwachitsanzo, kuyambitsa insulini musanadye).

Popewa kufalitsa matenda opatsirana, cholembera / cholembera chilichonse chimayenera kugwiritsidwa ntchito ndi wodwala m'modzi, ngakhale singano isinthidwe.

Ma cartridge a Humalog® ayenera kugwiritsidwa ntchito ndi ma syringes omwe ali ndi chizindikilo cha CE malinga ndi malangizo a wopanga chipangizocho.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Panthawi ya hypoglycemia, chidwi ndi kuthamanga kwa zochitika zama psychomotor zimatha kuchepa. Izi zitha kukhala zowopsa nthawi zomwe maluso amenewa amafunikira makamaka (mwachitsanzo, kuyendetsa magalimoto kapena makina ogwiritsa ntchito).

Odwala ayenera kulangizidwa kuti azisamala kuti asawonongeke poyendetsa galimoto poyendetsa magalimoto ndi makina owongolera. Izi ndizofunikira kwambiri kwa odwala omwe ali ndi zofatsa kapena zosapezekapo zizindikiro, okhazikika a hypoglycemia kapena okhazikika a hypoglycemia. Zikatero, adotolo amayenera kuwunika momwe magalimoto amayendera odwala.

Malo osungira

Sungani mufiriji kutentha kwa 2-8 ° C.
Mankhwala omwe amagwiritsidwa ntchito mu cholembera / syringe cholembera amayenera kusungidwa kutentha kwambiri osapitirira 30 ° C osapitirira masiku 28.
Kuteteza ku dzuwa mwachindunji ndi kutentha. Osalola kuzizira.
Pewani kufikira ana.

Mayina ndi maadiresi amalo opanga

Kupanga kwa fomu yomalizira Mlingo ndi ma CD oyambira:
"Lilly France." France (cartridgeges, QuickPen ™ syringe pensulo)
2 Ru du Colonel Lilly, 67640 Fegersheim, France

Kukhazikitsa kwachiwiri ndikupereka mawonekedwe oyang'anira:
Lilly France, France
2 Ru du Colonel Lilly, 67640 Fegersheim
kapena
Eli Lilly ndi Company, USA
Indianapolis, Indiana. 46285 (QuickPen ™ Syringe Pens)
kapena
JSC OPTAT, Russia
157092, dera la Kostroma, chigawo cha Susaninsky, ndi. Kumpoto, microdistrict. Kharitonovo

Chonde werengani Malangizo a QuickPen ™ Syringe pen Malangizo Ogwiritsira Ntchito Musanagwiritse Ntchito

Werengani bukuli musanayambe kugwiritsa ntchito insulin koyamba. Nthawi iliyonse mukalandira phukusi latsopano ndi zolembera za syPinge za QuickPen, muyenera kuwerenga malangizo kuti mugwiritsirenso, monga ikhoza kukhala ndi zidziwitso zosinthidwa. Chidziwitso chomwe chili m'malangizowa sichimachotsa zokambirana ndi dokotala wanu za matendawo ndi chithandizo chanu.

Chikwangwani cha QuickPen ™ Syringe cholembera ("Syringe pen") ndi cholembera chomwe sichitha, chomwe chili ndi mayunitsi 300 a insulini. Ndi cholembera chimodzi, mutha kupereka ma insulin angapo. Pogwiritsa ntchito cholembera ichi, mutha kulowa muyezo ndi chidziwitso cha 1 unit. Mutha kulowa kuchokera pa 1 mpaka 60 mayunitsi paliponse. Ngati mlingo wanu uposa mayunitsi 60, muyenera kuchita jakisoni wambiri. Ndi jakisoni aliyense, pisitoni imangoyenda pang'ono, ndipo mwina simungathe kuwona kusintha kwake. Piston imafika pansi pa cartridge pokhapokha mutagwiritsa ntchito zigawo zonse 300 zomwe zili mu cholembera.

Cholembera sichitha kugawidwa ndi anthu ena, ngakhale mutagwiritsa ntchito singano yatsopano. Osagwiritsanso ntchito singano. Osadutsa singano kwa anthu ena. Matenda atha kupatsirana ndi singano, zomwe zingayambitse matenda.

Momwe kusiyana kwa QuickPen ™ Syringe Pens:

Kukonzekera cholembera kuti insulin ikulandire:

• Sambani manja anu ndi sopo.
• Chongani cholembera kuti muone ngati ali ndi mtundu wa insulin yomwe mukufuna. Izi ndizofunikira kwambiri ngati mugwiritsa ntchito mitundu yambiri ya insulin.
• Musagwiritse ntchito zolembera zomwe zatha ntchito monga zalembedwera.
• Nthawi zonse gwiritsani ntchito singano yatsopano ndi jekeseni aliyense kupewa matenda komanso kupewa kutchingira singano.

Gawo 2 (kungoti kukonzekera Humalog Remix 25 ndi Humalog Remix 50):

• Pindani pang'ono cholembera pakati pa manja anu kangapo.
• Tembenuzani syringe nthawi 10.

Kulimbitsa ndikofunikira pakulondola kwa mlingo. Insulin iyenera kuwoneka yunifolomu.

• Onani mawonekedwe a insulini.

Humalog® iyenera kukhala yowonekera komanso yopanda utoto. Osagwiritsa ntchito ngati ndi mitambo, ali ndi utoto, kapena tinthu tating'onoting'ono kapena mawonekedwe.

Humalog® Remix 25 iyenera kukhala yoyera komanso yamtambo mutasakaniza. Osagwiritsa ntchito ngati chowonekera, kapena ngati ma tinthu kapena mavu alipo.

Humalog® Mix 50 iyenera kukhala yoyera komanso yamtambo mutasakaniza. Osagwiritsa ntchito ngati chowonekera, kapena ngati ma tinthu kapena mavu alipo.

Kuyang'ana cholembera kuti mugwiritse ntchito mankhwala osokoneza bongo

Kuyendera kotereku kuyenera kuchitika usanalowe jekeseni aliyense.

• Kuyang'ana cholembera kuti mupeze mankhwala osokoneza bongo kumachitika kuti muchotse mpweya mu singano ndi cartridge, yomwe imatha kudziunjikira nthawi yayitali, ndikuonetsetsa kuti cholembera chikugwiradi ntchito.
• Ngati simupanga cheke chotere musanalowe jekeseni iliyonse, mutha kulowa insulin yotsika kwambiri kapena kwambiri.

• Pitilizani kugwira cholembera ndi singano mmwamba. Dinani batani la mlingo mpaka litayima ndipo "0" iwonekere pazenera la dokotala. Mukugwira batani la mlingo, pang'onopang'ono werengani mpaka 5.

Muyenera kuwona insulin kumapeto kwa singano.

Ngati dontho la insulin silikupezeka kumapeto kwa singano, bwerezaninso njira zomwe mungayang'anire cholembera kuti mugwiritse ntchito mankhwala osokoneza bongo. Cheke chitha kuchitidwa osapitilira kanayi.
- Ngati insulini ilibe kuoneka, sinthani singano ndikubwereza cheke cholembera chida chamankhwala.

Kukhalapo kwa thovu laling'ono labwinobwino nkwachibadwa ndipo sikukhudza mlingo womwe umaperekedwa.

Sankhani

• Mutha kulowa kuchokera pa 1 mpaka 60 mayunitsi paliponse.
• Ngati mlingo wanu uposa 60 mayunitsi. Muyenera kuchita jakisoni wambiri.

Ngati mukufuna thandizo la momwe mungagawire bwino mankhwalawa, funsani dokotala.
- Pa jakisoni aliyense, gwiritsani ntchito singano yatsopano ndikubwereza momwe mungayang'anire cholembera kuti mugwire mankhwala.

• Yatsani batani la mlingo kuti mupeze insulin yomwe mukufuna. Chizindikiro cha mlingo uyenera kukhala pamzere womwewo ndi kuchuluka kwa zigawo zomwe zikugwirizana ndi mlingo wanu.

Nthawi imodzi, batani loyendetsa mlingo limasunthira 1 unit.
- Nthawi iliyonse mukatembenuza batani la mlingo, kumadina kumapangidwa.
- Simuyenera kusankha mlingo wowerengetsa makonda, chifukwa mlingo woyipa ungafanane motere.
- Mlingo umatha kusinthidwa ndikutembenuza batani mu njira yomwe mukufuna kufikira nthawi imeneyo. mpaka chithunzi chofanana ndi mlingo wanu chikuwonekera pawonetsero wa mlingo pazomwezo ndi chizindikiro cha mlingo.
- Ngakhale manambala akuwonetsedwa pamwambowu.
- Manambala osavomerezeka, nambala 1 itatha, akuwonetsedwa ndi mizere yolimba.

• Nthawi zonse muziwunikira nambala yomwe ili pawindo lotsozera kuti muwonetsetse kuti mlingo womwe mwalowa ndi wolondola.
• Ngati pali insulin yotsalira mu cholembera kuposa momwe mungafunire, simungathe kugwiritsa ntchito cholembera kuti mulowetse muyezo womwe mukufuna.
• Ngati mukufuna kulowa mayunitsi ambiri kuposa omwe atsalira mu cholembera. Mutha:

Lowetsani kuchuluka komwe kwatsala cholembera, kenako gwiritsani ntchito cholembera chatsopanocho kuti mupeze mlingo wotsalawo.
- tengani cholembera chatsopano ndi kulowa muyezo wathunthu.

Kubaya

• Lowetsani insulin monga momwe dokotala wasonyezera.
• Pa jakisoni aliyense, sinthani (sinthani) malo opaka jekeseni.
• Musayese kusintha mlingo pakati pa jakisoni.

Insulin imalowetsedwa pansi pa khungu (subcutaneously) kukhoma kwamkati, matako, matako, kapena mapewa.

• Ikani singano pansi pa khungu.
• Kanikizani batani la mlingo mpaka njira yonse.

Gwirani pansi batani. kuwerengetsa pang'onopang'ono mpaka 5, kenako ndikuchotsa singano pakhungu.

Osayesa kupereka insulin potembenuza batani la mlingo. Mukazungulira batani la mlingo, insulini SIYONSEZA.

• Chotsani singano pakhungu.
  Izi sizachilendo ngati dontho la insulin lingadutse kumphuno ya singano. ” Izi sizikhudzanso kuchuluka kwa mlingo wanu.
• Onani nambala yomwe ili pawindo la chizindikiro.
  - Ngati chiwonetsero chazenera cha mlingo ndi "0", ndiye. Mwalowa muyezo womwe mwamwa mokwanira.
  - Ngati simukuwona "0" pawindo lowonetsa, musayikenso mankhwalawo. Ikani singano pansi pa khungu kachiwiri ndikumaliza jakisoni.
  -Ngati mukuganiza kuti mlingo womwe mwayamwa sunalowe mokwanira, musabwereze jakisoni. Yang'anani shuga wanu wamagazi ndikuchita monga akuwongoleredwera ndi katswiri wanu wazachipatala.
  - Ngati mukufuna kupanga jakisoni 2 pa mlingo wonse, musaiwale jekeseni wachiwiri.

Ndi jakisoni aliyense, pisitoni imangoyenda pang'ono, ndipo mwina simungathe kuwona kusintha kwake.

Mukaona dontho la magazi mutachotsa singano pakhungu, pindani pang'onopang'ono ndi yopyapyala yoyera kapena kachakumwa ka zakumwa. Osazipukusa malowa.

Kutaya zolembera ndi singano

• Ikani singano zogwiritsidwa ntchito mu chidebe cha sharps kapena chidebe cholimba cha pulasitiki chokhala ndi chivindikiro cholimba. Osataya singano m'malo osankhidwa zinyalala za m'nyumba.
• Chingwe chomwe chagwiritsidwa ntchito chitha kutayidwa ndi zinyalala za m'nyumba mutachotsa singano.
• Lumikizanani ndi adokotala za momwe mungatayire chida chanu cha ubweya.
• Malangizo ogwiritsa ntchito pobayira singano mu bukuli samachotsa malamulo, malangizo kapena mfundo zoyambitsidwa ndi bungwe lililonse.

Kusungidwa kwa cholembera

• Sungani zolembera zosagwiritsidwa ntchito mufiriji pa kutentha kwa 2 ° C mpaka 8 ° C.
• Osamasula insulin yanu. Ngati idapanga chisanu, musagwiritse ntchito.
• Ma cholembera osagwiritsidwa ntchito amatha kusungidwa mpaka tsiku lotha ntchito likawonetsedwa, ngati atasungidwa mufiriji.

Chingwe cha syringe chikugwiritsidwa ntchito

• Sungani cholembera chomwe mukugwiritsa ntchito panopo kutentha mpaka 30 ° C pamalo otetezedwa ndi kutentha ndi kuwala.
• Tsiku lotha ntchito likatulutsidwa pamapaketi, cholembera chogwiritsidwa ntchito chimayenera kutayidwa, ngakhale insulini ikadalimo.

Zovuta

• Ngati simungathe kuchotsa kapu ku cholembera, muzipotoza, kenako ndikukoka.
• Ngati mlingo woyimba piritsi utakankhidwa mwamphamvu:
  - Kanikizani batani loyimba pang'onopang'ono. Kukanikiza pang'onopang'ono batani la kuyimba pang'onopang'ono kumapangitsa kuti jakisoniyo akhale wosavuta.
  "Singano ingatsekedwe." Ikani singano yatsopano ndikuyang'ana cholembera kuti mukhale mankhwala osokoneza bongo.
  -Nkutheka kuti fumbi kapena zinthu zina zalowa mu cholembera. Ponyani cholembera choterocho ndikutenga chatsopano.

Ngati muli ndi mafunso kapena kuda nkhawa pogwiritsa ntchito QuickPen Syringe pen, kulumikizana ndi Eli Lilly kapena wothandizira zaumoyo wanu.

Zoyimira ku Russia:

Eli Lilly Vostok S.A., 123112, Moscow
Presnenskaya embankment, d. 10

Mankhwala apamwamba kwambiri achi French, a insulin Humalog, atsimikizira kuti ndi apamwamba kuposa ma analogues, omwe amapezeka chifukwa chophatikizika bwino pazinthu zazikulu zomwe zimagwira ntchito. Kugwiritsa ntchito insulini iyi kumathandizanso kwambiri kuti athane ndi hyperglycemia mwa odwala omwe ali ndi matenda ashuga.

Kufotokozera kwa Insulin Humalog

Insulin Humalog Yachidule imapangidwa ndi kampani yaku France ya Lilly France, ndipo mawonekedwe ake otulutsidwa ndi njira yosavuta komanso yopanda utoto, yokhazikitsidwa ndi kapisolo kapena cartridge. Zotsalazo zitha kugulitsidwa zonse ngati gawo la syringe yokonzedwa kale, kapena padera magawo asanu pa 3 ml pachimake. Monga njira ina, makonzedwe angapo a Humalog Mix amapangidwa mwa kuyimitsidwa kwa kayendetsedwe koyenda, pomwe Humalog Remix imatha kutumikiridwa kudzera m'mitsetse.

Chofunikira chachikulu cha Humalog ndi insulin lispro - mankhwala a magawo awiri pa 100 IU pa 1 ml ya yankho, zomwe zimayendetsedwa ndi izi:

• glycerol
• metacresol
• zinc oxide
• sodium hydrogen phosphate heptahydrate,
• hydrochloric acid solution,
• sodium hydroxide solution.

Kuchokera pakuwona kwa gulu lazachipatala ndi zamankhwala, Humalog amatanthauza kufananizira kwa insulin yaumunthu yochepa, koma imasiyana ndi iwo m'njira zotsatizana za ma amino acid. Ntchito yayikulu ya mankhwalawa ndikuwongolera kutulutsa kwa glucose, ngakhale ilinso ndi katundu wa anabolic. Pharmacologically, imachita motere: kuwonjezeka kwa glycogen, mafuta acids ndi glycerol kumapangidwira minofu minofu, komanso kuwonjezeka kwa kuchuluka kwa mapuloteni komanso kumwa kwa amino acid ndi thupi. Mofananamo, njira monga glycogenolysis, gluconeogeneis, lipolysis, mapuloteni catabolism, ndi ketogeneis zimayamba kuchepa.

Kafukufuku wasonyeza kuti mwa odwala omwe ali ndi mitundu yonse ya shuga m'matumbo atatha kudya, kuchuluka kwa shuga kumachepa kwambiri ngati Humalog imagwiritsidwa ntchito m'malo mwa insulin ina yosungunuka.

Ndikofunika kukumbukira kuti ngati wodwala yemwe ali ndi matenda ashuga nthawi yomweyo amalandira insulin yochepa komanso basal insulin, ndikofunikira kusintha mlingo wa mankhwala oyamba ndi achiwiri kuti mukhale ndi zotsatira zabwino. Ngakhale kuti Humalog ndi ya ma insulin osakhalitsa, nthawi yotsiriza yochita zake imatsimikizidwa ndi zinthu zingapo payekha kwa wodwala aliyense:

• Mlingo
• tsamba la jakisoni
• kutentha kwa thupi
• zolimbitsa thupi
• mtundu wamagazi.

Payokha, ndikofunikira kudziwa kuti Humalog insulin imathandizanso chimodzimodzi kwa odwala matenda ashuga komanso pa ana kapena achinyamata. Sizosasinthika kuti mphamvu ya mankhwalawa sizimadalira kupezeka kwa aimpso kapena chiwindi m'thupi, ndipo akaphatikizidwa ndi Mlingo wambiri wa sulfonylurea, kuchuluka kwa hemoglobin ya glycated kumachepa kwambiri. Mwambiri, pakhala pali kuchepa kwakukulu kwa chiwerengero cha nocturnal hypoglycemia, pomwe odwala matenda ashuga nthawi zambiri amavutika ngati samamwa mankhwala oyenera.

Makhalidwe a Humalog insulin omwe akuwonetsedwa manambala amawoneka motere: kuyambika kwa mphindi 15 pambuyo pa jakisoni, nthawi yochitapo kanthu ikuchokera maola awiri mpaka asanu. Kumbali ina, kugwiritsa ntchito bwino mankhwalawa kumakhala kotsika poyerekeza ndi komwe kumachitika mwanjira inayake, ndipo pomwepo, itha kugwiritsidwa ntchito mphindi 15 zokha tisanadye, osati 30-31, monga momwe zimakhalira ndi ma insulini ena.

Zisonyezero zamankhwala

Insulin Humalog imapangidwira odwala onse omwe ali ndi vuto la hyperglycemia ndipo amafuna insulin. Itha kukhala funso la mitundu iwiri ya matenda ashuga a mellitus, omwe ndi matenda omwe amadalira insulin, ndi matenda amtundu wa 2, omwe shuga ya magazi amawonjezeka pafupipafupi pambuyo chakudya chomwe chimakhala ndi chakudya.

Insulin Humalog-yofikira mwachidule imakhala othandiza nthawi iliyonse yamatendawa, komanso kwa odwala onse azaka ndi azaka zonse. Monga mankhwala othandiza, kuphatikiza kwake ndi ma insulin apakati komanso a nthawi yayitali, omwe amavomerezedwa ndi adokotala, amawaganiziridwa.

Malangizo ogwiritsira ntchito insulin Humalog

Kugwiritsa ntchito Humalog kumayambira powerengera mlingo, womwe umatsimikiziridwa payekha ndi adotolo, kutengera ndi kusowa kwa matenda a shuga. Mankhwalawa atha kuperekedwa musanadye komanso pambuyo poti mudye, ngakhale njira yoyamba ndiyabwino. Onetsetsani kuti mukukumbukira kuti yankho siliyenera kuzizira, koma likufanizira kutentha kwa chipinda. Nthawi zambiri, syringe, cholembera, kapena pampu ya insulini imagwiritsidwa ntchito poigwiritsa ntchito, jekeseni mwanjira ina, komabe, pazinthu zina, kulowetsedwa kwa kulowetsedwa kumaloledwa.

Jakisoni wotsekemera amachitika makamaka m'tchafu, phewa, pamimba kapena matako, kusinthana malo a jekeseni kuti chinthu chomwecho sichikugwiranso ntchito kamodzi pamwezi. Kusamalidwa kuyenera kuthandizidwa kuti musalowe m'mitsempha, komanso sikulimbikitsidwa kutikita pakhungu pambuyo poti mwabayidwa. Ma humalog omwe adagulidwa ngati mawonekedwe a cartridge a syringe cholembera agwiritsidwa ntchito motere:

1. muyenera kusamba m'manja ndi madzi ofunda ndikusankha malo a jekeseni,
2. khungu m'malo jakisoni ndi opha tizilombo toyambitsa matenda,
3. chophimba chimachotsedwa pa singano.
4. Khungu limakonzedwa pamanja pokoka kapena kukanikiza kuti khola lipezeke,
5. singano imayilidwa pakhungu, batani la syringe limakanikizidwa,
6. singano imachotsedwa, tsamba la jakisalo limakanikizidwa modekha kwa masekondi angapo (popanda kutsitsa ndi kutikisa),
7. mothandizidwa ndi kapu yoteteza, singanoyo imatembenuzidwa ndikuchotsedwa.

Malamulo onsewa amagwira ntchito pamitundu yotere ya mankhwalawa monga Humalog Remix 25 ndi Humalog Remix 50, yopangidwa mwanjira yoyimitsidwa. Kusiyanako kuli pakuwoneka ndi kukonzekera kwa mitundu yosiyanasiyana ya mankhwala: yankho lake liyenera kukhala lopanda utoto komanso wowonekera, pomwe limakhala lokonzeka kugwiritsidwa ntchito, pomwe kuyimitsidwa kwake kuyenera kugwedezeka kangapo kuti katoni ikhale ndi yunifolomu, yamitambo, yofanana ndi mkaka.

Kuwongolera kwapakati pa Humalog kumachitika pang'onopang'ono pogwiritsa ntchito njira yolumikizira, momwe yankho limaphatikizidwa ndi yankho la 0.9% sodium chloride kapena 5% dextrose solution. Kugwiritsa ntchito mapampu a insulin poyambitsa Humalog amakonzedwa molingana ndi malangizo omwe aphatikizidwa ndi chipangizocho. Mukamagwira jakisoni wamtundu uliwonse, muyenera kukumbukira kuchuluka kwa shuga komwe kumachepetsa 1 insulin kuti muwoneke molondola mlingo ndi momwe thupi limagwirira. Pa avareji, chizindikirochi ndi 2.0 mmol / L pokonzekera ma insulin ambiri, zomwe zimachitikiranso Humalog.

Kuchita ndi mankhwala ena

Kuphatikiza kwa mankhwalawa kwa Humalog ndi mankhwala ena ambiri kumafanana ndi kufanana kwake. Chifukwa chake, zotsatira za hypoglycemic yothetsera vutoli zimachepetsedwa ndikuphatikizidwa ndi njira yolerera pakamwa, glucocorticosteroids, mahomoni a chithokomiro, mitundu yambiri ya okodzetsa ndi antidepressants, komanso nicotinic acid.

Nthawi yomweyo, mphamvu ya insulin iyi imakulirakulira pamodzi ndi mankhwala pogwiritsa ntchito:

• beta blockers,
• Mowa ndi mankhwala ozikirapo,
• anabolic steroids
• othandizira pakamwa
• sulfonamides.

Migwirizano ndi magwiritsidwe akusungidwa

Humalog iyenera kusungidwa m'malo osavomerezeka ndi ana mkati mwa firiji wamba, kutentha kwa +2 mpaka +8 digiri Celsius. Moyo wa alumali wamba ndi zaka ziwiri. Ngati phukusi latsegulidwa kale, insulini iyi iyenera kusungidwa kutentha kutentha +15 mpaka +25 Celsius.

Chisamaliro chikuyenera kuthandizidwa kuti mankhwalawa asatenthe komanso kuti alibe dzuwa. Mukayamba kuyamba kugwiritsa ntchito, moyo wa alumali umachepetsedwa kukhala masiku 28.

Zofananira mwachindunji za Humalog zikuyenera kuwonedwa ngati kukonzekera konse kwa insulin kumathandizanso odwala matenda ashuga chimodzimodzi.Mwa zina mwazotchuka kwambiri ndi Actrapid, Vosulin, Gensulin, Insugen, Insular, Humodar, Isofan, Protafan ndi Homolong.