Adebit: malangizo ogwiritsira ntchito, mtengo, ndemanga za madokotala ndi odwala

Chenjezo liyenera kuperekedwa limodzi ndi okodzetsa (makamaka ndi zotumphukira za thiazide). Chifukwa cha chiwopsezo cha lactic acidosis, kuyezetsa magazi kuyenera kuchitidwa miyezi isanu ndi umodzi iliyonse, ndipo ntchito ya chiwindi ndi impso iyenera kuyang'aniridwa. Pamaso pa opareshoni, kusintha kwa insulini ndikofunikira. Pa chithandizo, simungamwe mowa, chifukwa Nthawi zina, mowa ungachitike.

Mafotokozedwe a magulu a nosological

Siyani ndemanga yanu

Chidziwitso Chaposachedwa Chosowa Chidziwitso, ‰

Zikalata zolembetsera Adebit

• S-8-242 N2016

Webusayiti yovomerezeka ya kampani RLS ®. Ensaikulopediya yayikulu ya mankhwala osokoneza bongo ndi katundu wa mankhwala omwe amapezeka ku Russia Internet. Ndondomeko yamankhwala Rlsnet.ru imapatsa ogwiritsa ntchito malangizo, mitengo ndi mafotokozedwe a mankhwala, zowonjezera pazakudya, zida zamankhwala, zida zamankhwala ndi zina. Maupangiri a pharmacological akuphatikiza chidziwitso cha kapangidwe ndi mawonekedwe amamasulidwe, zochitika zamankhwala, zisonyezo zogwiritsidwa ntchito, contraindication, zotsatira zoyipa, kugwiritsa ntchito mankhwala, njira yogwiritsira ntchito mankhwala, makampani opanga mankhwala. Ndondomeko ya mankhwala ili ndi mitengo yamankhwala ndi mankhwala ku Moscow ndi mizinda ina ya Russia.

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Zinthu zina zambiri zosangalatsa

Maumwini onse ndi otetezedwa.

Kugwiritsa ntchito malonda pazinthu sikuloledwa.

Chidziwitsochi cholinga chake ndi akatswiri azachipatala.

Adebit - malangizo, mtengo, ndemanga ndi fanizo la mankhwala

Adebit - wothandizira antidiabetesic pakamwa pakamwa kwa odwala osadalira insulin. Sichimayambitsa hypoglycemia mwa anthu athanzi; itha kutumikiridwa ndi zotumphukira za sulfonylurea.

Zochizira

Mankhwala othandizira pakamwa a gulu la Biguanide. Zimatha kusintha magwiritsidwe a shuga ndikuthandizira gwero la anaerobic.

Adebit sichimayambitsa hypoglycemia mwa anthu athanzi. Itha kuperekedwa monga kuphatikiza ndi antidiabetesic oral othandizira a sulfonamide mtundu.

• Type 2 shuga mellitus mu odwala, kuphatikiza mankhwala ndi sulfonylurea, zotumphukira, kusamalira kupanga amkati insulin.
• Kunenepa kwambiri kumayambiriro kwa matenda ashuga.
• Kuperewera kwa kagayidwe kachakudya ka shuga (kuphatikiza ndi insulin).

Contraindication

Acidosis kapena kupezeka kwa zinthu zina za lactic acidosis: kupuma kwa mapapo, kulephera kwamtima, matenda aimpso kapena kwa chiwindi, matenda osokoneza bongo, matenda opatsirana, matenda am'mimba, pachimake pancreatitis, malungo, hypovolemia, uchidakwa wambiri, kugwiritsa ntchito okodzetsa,Kukonzekera opaleshoni ndi mikhalidwe pambuyo pa opaleshoni, zaka za senile, kutenga pakati.

Njira yogwiritsira ntchito

Kugwiritsa ntchito ndi mlingo umatsimikiziridwa ndi dokotala. Mlingo woyambirira umachokera kwa 100-150 mg tsiku lililonse (mpaka katatu piritsi 1), ndimalo ochepa osaloledwa akatha kudya.

M'tsogolomo, malinga ndi momwe wodwalayo alili, mankhwalawa amatha kuchuluka ndi piritsi limodzi pakapita masiku awiri kapena anayi. Mlingo wambiri patsiku ndi mapiritsi 300 mg kapena 6, omwe amagawidwa pang'onopang'ono 3 kapena 4.

Mlingo wokonza nthawi zambiri umakhala 200 mg tsiku lililonse (mapiritsi 4).

Zotsatira zoyipa

• Kusanza, kusanza, kutsekula m'mimba, kusowa kwa chilimbikitso ndi kulawa kwazitsulo mkamwa. Zodandaula izi ndizotheka mukamamwa mankhwalawa pamimba yopanda kanthu, zimazimiririka pambuyo pochepetsa kwakanthawi.
• Malabsorption a vitamini B12, lactic acidosis, idiosyncrasy. Kukula kwa zinthu zotere ndi kotheka popanda kuzindikira contraindication mankhwala.

Malangizo apadera

Pamafunika kugwiritsa ntchito mosamala mankhwalawa ndi diuretics, thiazide derivatives (chifukwa cha chiopsezo cha lactic acidosis, hypovolemia), njira zakulera pakamwa (chifukwa cha kuchepa kwa kuchitapo), corticosteroids (amachepetsa mphamvu ya Adebit), mankhwala omwe amalimbikitsa nthawi yowonjezera magazi (Adebit) imawonjezera zotsatira zawo).

Mankhwala a Adebite, kuwunika pafupipafupi chithunzi cha magazi, komanso ntchito za impso ndi chiwindi ndikofunikira, zomwe zimagwirizanitsidwa ndi chiopsezo chokhala ndi lactic acidosis.

Ngati mukumva kupweteka m'mimba thirakiti, kugona, kupumira mwachangu, muyenera kufunsa dokotala. Kutsatira mosamalitsa chakudyacho ndi kudzipatula kwathunthu kwa mowa, chifukwa nthawi zina kutsutsana kwake kumachitika.

Odwala omwe ali ndi tsankho lactose, akhoza kukhala ndi mavuto ndi kugaya kwam'mimba chifukwa cha zomwe zili pamapiritsi.

"Adebit" imasungidwa kutentha firiji, kutaya nthawi ikatha. Alumali moyo - zaka 5.

CHOKONZEDWA MALO OGULITSA

Zotsatira za pharmacological

Kutsitsa kwa shuga kwa Adebit kumapangitsanso kukoka kwa glucose komanso minyewa (makamaka minofu minofu), kutsitsa kuyamwa kwa glucose m'matumbo ang'ono ndi kusintha kwake kulowa m'magazi, ndikutseka gluconeogeneis m'chiwindi. Mankhwala amathandizira anaerobic glycolysis, amalimbikitsa chiwopsezo cha maselo ku insulin.

Adebit imayambitsa zotsatira zovulaza pang'ono, zimachepetsa chilimbikitso, zomwe zimathandizira kudya komanso zimathandizira kuchepetsa kunenepa kwambiri. Kuphatikiza apo ali ndi katundu wopondaponda.

The achire zotsatira akuyamba pambuyo 2-4 maola, kufika pazofunikira pambuyo 5 maola. Kutalika konse kwa kuchitapo mpaka maola 8. Thupi limakhala ndi bioavailability wathunthu, limatengedwa mwachangu m'mimba. Imafufutidwa kudzera mu impso.

• lembani matenda ashuga achikulire awiri, osakanikirana ndi sulfonylureas ndi kusakwanira kwawo
• mtundu 1 shuga, limodzi ndi insulin, pakalibe shuga kagayidwe
• kunenepa.

Momwe mungatenge ADEBIT

Kulandila ndi zakudya kawiri patsiku: m'mawa ndi madzulo. Mlingo woyambirira ndi 100-150 mg (piritsi 1 katatu patsiku). Mlingo wa tsiku ndi tsiku umagwirizana ndi shuga wamagazi, koma osapitilira 300 mg / tsiku (mapiritsi 6 mu waukulu zitatu). Mlingo wokonza ndi mapiritsi 4 patsiku.

Zochizira kunenepa kwambiri, tsiku lililonse 100 mg ndi mankhwala.

Kuchita zinthu zina

Adebit ikhoza kugwiritsidwa ntchito limodzi ndi insulin, mankhwalawa amawonjezera ndikuwonjezera mphamvu yake. Zinthu monga chlorpromazine, mahomoni a chithokomiro, corticosteroids, ndi diuretics amachepetsa mphamvu yochepetsera shuga ya Adebit.Salicylates, MAO zoletsa ndi kukonzekera kwa sulfonylurea - konzekerani.

Kugwiritsa ntchito limodzi ndi njira zakulera za mahomoni kumafooketsa mphamvu ya mankhwala onse awiri. Adebit imapititsa patsogolo zochita za thrombolytics.

Kudya kwa Adebit kuyenera kutsagana ndi kuwunika pafupipafupi magazi a shuga ndikuwunika ntchito ya impso.

Betaserc 24 mg - malangizo, ntchito, mtengo, ndemanga, analogies

Moni nonse! Tipitiliza kuunikanso za mankhwala, omwe adayamba pano ndi fanizo la Zovirax, akupitiliza "kuno" mwa nkhani ya enterofuril, kenako ndi ma analogi a Sinupret, kenako mu gawo "Kuyambitsa ndi Moyo Wathanzi". Lero mutu wathu ndi: "Beaserc 24 mg - malangizo, ntchito, mtengo, ndemanga, analogi". Pankhaniyi, ndalemba kale "apa" Uku ndikupitiliza.

Matenda a khutu lamkati, monga kuchepa kwa mitsempha ya m'mitsempha kapena labyrinthitis, yomwe imayambitsa kumva komanso chizungulire. Amatha kuchitika osati pakukalamba, komanso mwa achinyamata atatupa kwa khutu lapakati kapena kumwa mankhwala osokoneza bongo.

N`zosatheka kubwezeretsa ntchito ya mitsempha ya neurosensory ngati pakuwonongeka kwakukulu. Mavuto oterewa amathandizidwa pokhapokha nthawi yayitali. Ngati matendawa ayambitsidwa, ndiye kuti mwina muimitse machitidwe oyipa a minyewa ndikuwatchinjiriza, mankhwala amagwiritsidwa ntchito omwe amapangitsa kuti khutu lamkati lisafike.

Imodzi mwa mankhwalawa ndi betaserk 24 mg, malangizo, kugwiritsa ntchito, mtengo, ndemanga, analogies zomwe tikambirana pankhaniyi.

1.1 Zimayambitsa ndi Zizindikiro za matenda amkati mwamkati

Gawo lolowera la zoyeserera ndi zowunika zaumunthu zimayambira modabwitsa. Pali ma cell ama cell omwe amawona kugwedezeka kwamtundu ndi ma mutu a mutu, chifukwa chake amachititsa kumva komanso kusamala. Matenda a khutu lamkati ndiwotupa komanso osachiritsika.

Zoyambirira zimachitika chifukwa cholowera tizilomboti kuchokera khutu lapakati pa nthawi ya matenda a bacteria kapena bacteria. Choyambitsa chachiwiri chimatha kukhala kusokonezeka kwa mitsempha kapena kufa kwa mitsempha chifukwa cha matenda amitsempha, kuvulala kwamtundu wamtundu kapena kumwa mankhwala osokoneza bongo.

Zizindikiro zowonongeka kwa khutu lamkati makamaka zimakhala kutayika kwa makutu, komanso phokoso ndi kulira m'makutu, chizungulire, mseru, kapena kuchepa bwino. Koma ndikofunikira kulingalira kuti ngati wodwalayo ali ndi chizungulire, ndipo makutuwo amakhala abwinobwino, ndiye kuti chizungulire, monga lamulo, sichikugwirizana ndi khutu lamkati.

1.2 Mfundo zochizira matenda amkati

Ndikofunika kuti odwala azindikire kuti ngati maselo am'mamutu amwalira mosachiritsika, ndiye kuti chithandizo sichithandiza kwenikweni. Chifukwa chake, muyenera kuyiyambitsa posachedwa: Zizindikiro zoyambirira za kusamva komanso kumva bwino zikachitika.

Mukuchita kutupa, maantibayotiki amathandizidwa kulandira chithandizo, koma osati ototoxic, komanso mankhwala othana ndi kutupa omwe amachepetsa edema (diuretics, corticosteroids, hypertonic solution, antihistamines).

Kusintha maselo a trophic, multivitamini, detoxification mankhwala ndi mankhwala omwe amasintha machitidwe a metabolic mu ubongo komanso kupatsidwa kwake magazi (nootropics) akulimbikitsidwa.

1.3 Beaserc 24 mg - malangizo

Ndi gawo la gulu la antihistamines, lomwe ndi fanizo lopanga la mkhalapakati yemwe amatulutsidwa panthawiyi. Amayambitsa kusuntha kwa minofu, vasodilation, kutsitsa magazi, kuyang'ana pakhungu, bronchospasm, kuzizira ndi kuyambitsa zotupa za mucous.

Ma receptor omwe histamine imamangiriza imakhalapo pakatikati ndi zotumphukira zamitsempha, zomwe zimayambitsa mutu ndi migraines komanso chizungulire.

Betaserk imamangirira ku histamine receptors, kuphatikiza khutu lamkati, chifukwa chake imatha kukonza kubwezeretsanso kwa ma capillaries ake ndi maselo a trophic.

Chifukwa cha kuchuluka kwakuchulukirachulukira mu beseni la chotupa chachikulu, kupanikizika kwa lymph mu labyrinth ndi curl kumakhala kwamtundu uliwonse. Imathanso kusintha kulowetsedwa pamitsempha yamaubongo.

Imalepheretsa zolandilira mu nati ya vestibular analyzer.

Chifukwa chogwiritsa ntchito betaserka, phokoso ndi tinnitus amachepetsa, kugunda kwa chizungulire ndikosowa, ndipo kumva kumakhala bwino, makamaka koyambirira kwamatenda. Betaserc imatengedwa mwachangu ndikuchotsa kwathunthu kuchokera mthupi ndi impso mu maola 24, osadziunjikira, chifukwa chake imakhala yoyenera kwa anthu achikulire.

1.4 Malamulo ogwiritsira ntchito Betaserc 24 mg

Mankhwalawa amalembedwa kwa odwala omwe ali ndi vuto la kupindika komanso kuwunika kwa labyrinth; amathandiza odwala kuthana ndi chizungulire, chomwe chimaphatikizidwa ndi mseru, kusanza, tinnitus ndi kumva.

Amasonyezedwa kukomoka kwa khutu lamkati, matenda a Meniere kapena matenda, kutsekeka ndi chizungulire chochepa, komanso kupitirira kwa kutaya kwa makutu.

Betaserc 24 mg imafotokozedwa chifukwa cha zovuta zochizira encephalopathy zomwe zimachitika pambuyo povulala, komanso atherosulinosis ya ziwiya zamafuta ndi vertebrobasilar insufficiency.

Contraindication pakugwiritsa ntchito kwake kudzakhala mphumu ya bronchial, komanso zilonda zam'mimba kapena duodenum yowonjezera. Sizingagwiritsidwe ntchito chifukwa cha ziwopsezo zomwe zimapangira mankhwala osokoneza bongo kapena zina zowonjezera.

Imasungidwa kwa amayi apakati mu trimester yoyamba, ndipo chachiwiri ndi chachitatu nthawi zina chimagwiritsidwa ntchito, koma malinga ndi zomwe akuwonetsa komanso moyang'aniridwa ndi dokotala. Mankhwalawa sakulimbikitsidwanso panthawi yachilendo, komanso ana ochepera zaka khumi ndi zisanu ndi zitatu, popeza palibe umboni wazomwe amachita pakadali pano.

Ndizoyenera kuganizira kuti betaserc sangakhale woledzera ndi antihistamines ena, chifukwa amachepetsa kuyendetsa bwino kwa oyambayo.

1.5 Zotsatira zoyipa

Odwala adazindikira kuti kuchokera pakugwiritsidwa ntchito, kulemera m'mimba, mseru, kusanza ndi kutsekula m'mimba kumatha kuchitika, chifukwa chomwe chikhala chofunikira kuchepetsa mlingo, ndikugwiritsanso ntchito mankhwalawa mukatha kudya. Thupi lawo siligwiritsidwa ntchito ngati zotupa pakhungu silichulukirapo.

Ndi ntchito kwa nthawi yayitali, chizungulire, palpitations, redness pakhungu, bronchospasm ndi kutsika kwa magazi. Zizindikiro zimazimiririka atasiya njira zamankhwala komanso chithandizo chamankhwala.

1.6 mawonekedwe otulutsira, mtengo wake ndi mlingo

Makampani opanga mankhwala amapangira mankhwalawa mapiritsi a 8,16 ndi 24 mg, mu paketi imodzi akhoza kukhala 20, 30 kapena 60. Mtengo wapakati wa chithuza cha mapiritsi khumi betaserk 24mg - pafupifupi ma ruble 240, 16 mg - 220, ndi mtengo wa 8 mg - 140 rubles.

Amadyedwa nthawi yomweyo mukatha kudya ndikusambitsidwa ndi madzi oyera. Nthawi zambiri, wodwalayo amalimbikitsidwa mapiritsi a 1-2 patsiku la 8 mg kapena limodzi pa mlingo wa 16 mg katatu patsiku, ndipo ngati ali 24 mg, ndiye kuti amaperekedwa kawiri pa tsiku.

1.8.1 Betahistine

Izi zimaphatikizapo mankhwala onse okhala betahistine kuphatikiza mapiritsi okhala ndi dzina lomweli. Zida izi ndizofanana umboni ndi zotsutsana. Zotsatira zoyipa zidzakhala chimodzimodzi.. Athanawati sizimasokoneza luso loyendetsa magalimoto kapena kugwira ntchito yomwe imagwirizana ndi kudzipereka.

Amapezanso bwino ndi mutu komanso chizungulire, chomwe chimawoneka mwa amayi kumayambiriro kwa kusintha kwa thupi.

Zowona, odwala amazindikira kuti zotsatira zake kugwiritsa ntchito betagestin zidzakhala kokha pambuyo pa milungu iwiri ya chithandizo ndipo sizikhala chokhazikika, ngakhale ndikugwiritsa ntchito nthawi yayitali chizungulire amachepetsa.

Komano mtengo Kukonzekera kumakhala kocheperako poyerekezera ndi kubaserc ndipo kumakhala koyenera kwa nthawi yayitali komanso nthawi zonse.

1.8.2 Vestibo

Analog ina ya betaserk ndi zikomo, chinthu chogwiritsa ntchito chida ichi ndi betahistine. Odwala amadziwa zabwino zomwe mankhwalawa amathandizira, ngakhale kuti zimasowa msanga, ndikofunikira kumaliza kugwiritsa ntchito. Analog ya beteserk iyi siyotsika mtengo - mtengo wamba siwo zikomo pafupifupi ma ruble 140 pamapiritsi khumi.

Magulu ena a mankhwalawa amagwiritsidwa ntchito pochiza matenda amkati, mwachitsanzo, munthawi yovuta kwambiri, odwala amamulembera mankhwala a antibacterial ndi mahomoni corticosteroid kuti achepetse kutupa, komanso njira zothetsera shuga za glucose kapena magnesium sulfate kuti muchepetse minyewa ya minyewa komanso kupewera kuzungulira kwa ngalande yopingasa.

1.8.3 Cavinton ndi vinpocetine

Gulu lina la mankhwala omwe amachepetsa chizungulire mwa odwala, komanso kukonza makutu, ndimankhwala omwe amakhudza kuchuluka kwa mitsempha ya magazi muubongo, kukulitsa ma capillaries. oyimira gulu lino otchuka ndi madotolo ali cavinton ndi vinpocetine.

Onykot amasintha minofu yosalala ya khoma lamitsempha, ndikuthandizira pakukula kwake, kuchepetsa kuthamanga kwa magazi, kuwonjezera mpweya ndi mpweya m'magazi amitsempha.

1.8.4 Piracetam, Cinnarizine, Phezam, ndi Cerebrolysin

Nootropics imatha kuonedwa ngati fanifes ya betaserk - mankhwala omwe amalimbikitsa kagayidwe mu maselo a mitsempha ndikuwongolera nawonso, komanso kulimbitsa khoma lamitsempha. Izi zikuphatikiza piracetam, cinnarizine, fezam ndi cerebrolesin.

Kupititsa patsogolo kogwiritsa ntchito sikumachitika nthawi yomweyo, koma pokhapokha ngati mukugwiritsa ntchito nthawi yayitali komanso kuphatikiza mankhwala ena, kuphatikizapo anticoagulants (trental, pentoxifylline).

Zotsalazo zimathandizira kuti magazi azisungunuka komanso kuti magazi azisintha.

1.8.5 Mavitamini a gulu B

Gulu lina la mankhwalawa zochizira makutu amitsempha yamagazi ndi Mavitamini Bomwe, pogwiritsa ntchito nthawi yayitali, amasintha kagayidwe m'maselo a mitsempha ndikuthandizira kuchira, mwakutero kuchepetsa tinnitus ndi chizungulire.

Malinga ndi mwambo, pomaliza, kanema pamutu wopatsidwa: "Betaserk"

Nkhani idakudziwitsani kuti: "Betaserk 24 mg - malangizo ogwiritsira ntchito, mtengo, ndemanga, analogues" Ndikukhulupirira kuti owerenga blog awa angaone kuti ndizothandiza kuzidziwa bwino mankhwala otchuka monga betaserk, kuwerenga malangizo ake ogwiritsa ntchito, mtengo, kuwunika, ma analogues.

Koma ndikufuna kukumbutsani kuti mankhwalawa ali ndi zomwe akuwonetsa, ndipo makamaka amatsutsana, chifukwa chake ndizosatheka kugwiritsa ntchito popanda kufunsa dokotala.

Buformin * (Buformin *) A10BA03 Buformin

• Kupanga kwa Hypoglycemic ndi othandizira ena

• E11 Matenda a shuga osadalira insulin
• Kunenepa kwambiri ndi E65-E68 ndi mitundu ina ya zakudya zopatsa thanzi

Piritsi 1 ili ndi buformin hydrochloride 50 mg, mu paketi yotupa ya ma PC 20,.

Zizindikiro zogwiritsidwa ntchito

Adebit imagwiritsidwa ntchito kwa odwala omwe samadalira insulin. Kulandila ndalama ndi anthu athanzi sikuti kumayambitsa hypoglycemia.

Mankhwala a Adebit amawerengedwa kuti:

• mtundu 2 shuga
• kunenepa
• zovuta zakudya zopatsa thanzi.

Mankhwala akuwonetsedwa ngati shuga osakhazikika aphatikizidwe ndi mahomoni.

Buku lamalangizo

Kupanga kwakukulu pa pharmacological ya Adebit ndi hypoglycemic.

Amachepetsa kuchuluka kwa shuga m'magazi a plasma, kuyang'anira kusinthasintha kwake masana, komanso kumachepetsa kufunikira kwa insulin. Chida chimenecho ndi cha gulu la Biguanides.

Amatengedwa pakamwa. Imathandizira anaerobic glycolysis mu zotumphukira zimakhala. Buformin monga gawo la Adebit amathandizira kuponderezana kwa gluconeogeneis m'chiwindi. Poterepa, pali kuchepa kwa mayamwidwe am'mimba kuchokera m'mimba.

Mankhwalawa amathandizira kuchepetsa kulakalaka. Buformin amayamba kuchita zinthu maola angapo atatha kumwa mankhwalawo ndikusunga katundu wake kwa maola asanu ndi atatu.

Mukamagwiritsa ntchito Adebit, momwe mungagwirizanirana ndi mankhwala ena muyenera kuziganizira:

1. katundu wotsitsa shuga wa mankhwalawo amayamba kufooka ngati atengedwa ndi zotuluka za phenothiazine, mahomoni opatsa mphamvu a chithokomiro, ma inhibitors a MAO, salicylates,
2. mankhwala mosamala ndi okodzetsa. Lactic acidosis ndi hypovolemia zitha kuchitika,
3. mankhwalawa amachepetsa urokinase,
4. munthawi yomweyo kugwiritsa ntchito mankhwala oletsa kubereka komanso corticosteroids, kuchepa kwamphamvu kwamankhwala kumachitika.

Mukatenga Adebit, mphamvu ya thrombolytics imatheka.

Kugwiritsa ntchito mankhwalawa kukutanthauza kutsatira malangizo apadera:

• ndikofunikira kuwunika pafupipafupi glycemia ndi kuphipha kwamkodzo shuga tsiku lililonse,
• Mlingo wa insulin uyenera kuchepetsedwa,
• munthawi ya mankhwala, muyenera kutsatira zakudya zovuta, kusankha zakudya zokhala ndi index yotsika ya glycemic.

Kumwa mowa ndikugwiritsa ntchito Adebit ndizoletsedwa. Mosamala, njira yothetsera vutoli imayikidwa pakamwa.

Fomu yotulutsidwa ya Adebite - mapiritsi, oikidwa mu chithuza chamtundu wa zidutswa 20. Kuyika - makatoni. Kusungidwa kwa mankhwalawa kuyenera kukwaniritsa zofunika: kutentha kwa firiji komanso zosaposa zaka zisanu.

Malangizo omwe amamwa mankhwalawa ali ndi kufotokoza kwa njira yogwiritsira ntchito ndi Mlingo.

Mlingo woyambirira umachokera ku 100 mpaka 150 mg patsiku, womwe umagawidwa kawiri kapena katatu, imwani piritsi limodzi mutatha kudya, kutsukidwa ndi madzi.

Chiwerengero cha mapiritsi chikuwonjezereka ndi chimodzi patatha masiku 2-4. Kuchuluka kwa tsiku ndi tsiku ndi 300 mg ya mankhwalawa, ogawidwa pamtundu wa 3-4. Kuti akhalebe ndi vutoli, amamwa 200 mg ya mankhwalawa patsiku, kuphwanya kanayi.

Makanema okhudzana nawo

Chidule cha mankhwala a matenda a shuga a 2:

Mphamvu zakuchiritsa za Adebit zimakhazikika pazotsatira zake za hypoglycemic. Ndi othandizira odwala matenda ashuga. Odwala omwe ali ndi kulemera kwambiri, akagwidwa, kulemera kwa thupi kumachepetsedwa chifukwa cha Adebit kuchepetsa kudya.

Zina mwazotsatira zake ndi kutsekula m'mimba, kupweteka kwa epigastric, chifukwa chake simuyenera kugwiritsa ntchito iwo omwe ali ndi matenda am'mimba. Mankhwalawa akuwonetsedwa kwa odwala omwe samadalira insulin, komanso matenda omwe amayamba ndi kunenepa kwambiri. Poyerekeza ndi zakumwa zomwe mumamwa, muyenera kutsatira kadyedwe, kusiya mowa ndikuyamba kukhala ndi moyo wathanzi.

• Imakhazikika pamisempha ya shuga kwa nthawi yayitali
• Imabwezeretsa kapangidwe ka insulin

Phunzirani zambiri. Osati mankhwala. ->

Njira Yogwiritsira Ntchito:

Gawani mkati ndi chakudya.

Monga othandizira odwala matenda ashuga, tengani, kuyambira pa 0,1 ga patsiku (50 mg m'mawa ndi madzulo), kutengera kusintha kwa shuga m'magazi ndi mkodzo, mlingo umatha kuwonjezeka pang'onopang'ono ndi 50 mg patsiku, koma tsiku lililonse mlingo sayenera kupitirira 300 mg

Mlingo wokonza nthawi zambiri umakhala 50-100 mg m'mawa ndi 50 mg madzulo.Pamaphatikizidwa ndi insulin, mlingo wotsiriza umachepetsedwa motsogozedwa ndi shuga m'magazi ndi mkodzo.

Pamodzi ndi kukonzekera kwa sulfonylurea, glibutide imalembedwa pokhapokha woyamba atalephera kuchepetsa hyperglycemia (kuchuluka kwa shuga m'magazi) ndi glucosuria (kukhalapo kwa shuga mumkodzo) mpaka muyezo wofunikira. kuphatikiza ndi anorexigenic / chilakolako kuponderezana / mankhwala).

Mapiritsi okhala ndi nthawi yayitali amapatsidwa piritsi limodzi (m'mawa), ndikukulitsa pang'onopang'ono mapiritsi 4 (m'mawa ndi madzulo mutatha kudya).

Zochitika:

Glibutide imalekereredwa bwino, koma kutaya mtima, kusanza, kusanza, kutsekula m'mimba (m'mimba), ndi kutsekemera kwazitsulo mkamwa kumatha kuonedwa. Tsiku lotsatira kuyambira pa chiyambi cha chithandizo (pambuyo pa mwezi kapena kupitirira), kufooka, kuchepa thupi kumatheka.

Zotsatira zoyipa zimachoka mwachangu ndi kuchepetsedwa kwa mankhwala kapena kusiya mankhwala.

Malo osungira:

Mankhwalawa amachokera mndandanda B. Pamalo pouma.

Buformin hydrochloride, Adebit, Butyl biguanide, Gliporal, Glibigid hydrochloride, Krebon, Silubin.

Butylbiguanide hydrochloride. White crystalline ufa wowawa. Piritsi losungunuka m'madzi ndi moledzera. Piritsi limodzi lokhala ndi nthawi yayitali limakhala ndi: 0.17 g ya buformin tosylate, yomwe imafanana ndi 0,1 g yogwira ntchito (glibutide).

Kukonzekera kofananako:

Diaformin (Diaformin) Glucovans (Glucovance) Oltar (Oltar) Glyukofazh (Glucophage) Maninil (Maninil)

Sanapeze zomwe mukufuna?
Malangizo onse amomwe mankhwalawa "glibutide" angapezeke pano:

Madokotala okondedwa!

Ngati mukumva kuperekera mankhwala kwa odwala anu - gawani zotsatira (kusiya ndemanga)! Kodi mankhwalawa adathandizira wodwala, kodi panali zotsatirapo zilizonse zomwe zimachitika panthawi ya chithandizo? Zomwe mukuwona zidzakhala zosangalatsa kwa anzanu komanso odwala.

Okondedwa odwala!

Ngati mankhwalawa adakulangizani inu ndipo mwalandira chithandizo chamankhwala, ndiwuzeni ngati chinali chothandiza (ngakhale chinathandizapo), ngakhale panali zovuta, zomwe mumakonda / zomwe simunazikonde. Anthu zikwizikwi akufuna kuyang'ana pa intaneti zamankhwala osiyanasiyana. Koma ochepa okha ndi omwe amawasiya. Ngati inu panokha simusiya ndemanga pamutuwu - ena onse sangakhale ndi zomwe angawerenge.

Zikomo kwambiri!/ sitemap-index.xml

Kufotokozera za mankhwala "Adebit"

Machitidwe a pharmacological Amachepetsa shuga m'magazi ndikusinthasintha kwake tsiku ndi tsiku, kufunika kwa insulin.

Zizindikiro zogwiritsidwa ntchito

• Type II shuga mellitus (kuphatikiza ndi mankhwala a sulfonylurea), kunenepa kwambiri kwa shuga, shuga wosakhazikika (kuphatikiza ndi insulin).

• 50 mg mapiritsi
• matuza 20, bokosi (bokosi) 2.

Pharmacodynamics wa mankhwala Hypoglycemic wothandizira pakamwa makonzedwe kuchokera pagulu la biguanides. Imagwira mwachindunji mphamvu ya anaerobic glycolysis mu zotumphukira zimakhala.

Amachepetsa gluconeogenesis m'chiwindi, amachepetsa mayamwidwe am'mimba kuchokera m'matumbo am'mimba (amalepheretsa matumbo alpha-glycosidases, amachepetsa kuphwanya kwa enzymatic kwa di-, oligo- ndi polysaccharides kwa monosaccharides), amachepetsa chilimbikitso.

Imachepetsa mphamvu ya plasma glucagon, imawonjezera chidwi cha zimakhala kuti insulin ikumangiriza insulini kupita ku insulin receptors. Kukhazikika kwa zochita kumachitika pambuyo pa maola 2-4, nthawi yochitapo kanthu ili pafupifupi maola 8.

Contraindication

• Hypersensitivity, ketonuria, hyperglycemic chikomokere, hypoglycemia, pakati, mkaka wa m`mawere. Lactic acidosis (kuphatikizapo mbiri)
• hepatic ndi / kapena aimpso kulephera, mtima kulephera, kupuma, infarction pachimake, uchidakwa, malungo, matenda opatsirana, albuminuria motsutsana ndi matenda a matenda a shuga.

Zotsatira zoyipa: Kuchepa kwa chakudya, nseru, kusanza, kufooka, kuchepa thupi, matenda am'mimba, m'mimba, kulawa kwamkati ndi zitsulo.

Mlingo Mkati, piritsi limodzi. Katatu patsiku mutatha kudya. Pazipita tsiku mlingo 300 mg mu 3-4 waukulu.

Zizindikiro za bongo: hypoglycemia, hypoglycemic coma.

Kugwirizana ndi mankhwala ena Mphamvu ya hypoglycemic imafooketsedwa ndi zotumphukira za phenothiazine, corticosteroids, mahomoni olimbikitsa a chithokomiro, estrogens, okodzetsa, Mao zoletsa, ma salicylates.

Malangizo apadera a kuvomerezedwa Ndikofunika kuwunika pafupipafupi kuchuluka kwa shuga mumkodzo, mulingo wa glycemia. Mukamalowa mankhwalawa ndi buformin, mlingo wa insulin umachepetsedwa pang'onopang'ono.

Mndandanda B

Alumali moyo miyezi 60.

Zomwe zimathandiza Bilobil: malangizo ndi kuwunika

Mankhwala achilengedwe a Bilobil ndi omwe amapanga maganizo.

Cholinga chake ndikuwongolera magwiridwe antchito a ubongo ndi machitidwe amanjenje. Amapangidwa pamaziko a mbewu zam'magazi olimbitsa thupi kuchokera ku gulu la maginki awiri. Mitundu iyi ya conifers imachokera kum'mawa kwa China, koma imalimidwa m'minda yambiri padziko lapansi.

Patsambali mupezapo zambiri zokhudzana ndi Bilobil: Malangizo onse omwe mungagwiritsire ntchito mankhwalawa, mitengo ya mankhwala, mankhwala, ndemanga zathunthu komanso zosakwanira, komanso ndemanga za anthu omwe amagwiritsa ntchito Bilobil kale. Mukufuna kusiya malingaliro anu? Chonde lembani ndemanga.

Kutulutsa mawonekedwe ndi kapangidwe kake

Chocolate bulau makapisozi. Makapisozi ali ndi ufa wofufuta wamtambo wokhala ndi tinthu tosalala tambiri.

• Kashiamu imodzi imakhala ngati yogwira ntchito: Kuuma kwa masamba a ginkgo biloba - 40 mg, wokhazikika kuti akhale ndi 9.6 mg wa flavono glycosides a ginkgo ndi 2.4 mg wa terpene lactones (ginkgolides ndi bilobalides) mu 40 mg.
• Zopatsa, lactose monohydrate, wowonda wa chimanga, talc, anhydrous colloidal silicon dioxide, magnesium stearate.
• Chigoba cha kapu: gelatin, indigotine (E132), azorubine (E122), oxide wofiira chitsulo * (E172), wakuda iron oxide (E 172), titanium dioxide (E 171).

Mankhwala

Bilobil ndi angioprotector wazomera zoyambira. Zotsatira zake, kuti kapangidwe kake ka mankhwalawa kamaphatikizira ginkgo biloba Tingafinye, monga terpene lactones ndi flavone glycosides, zida zake zogwiritsira ntchito kwachilengedwe zimalimbitsa kwambiri ndikuwonjezera kukondoweza kwa makoma amitsempha yamagazi, komanso kukonza kuthekera kwa magazi.

Malangizo a Bilobil amasonyezanso kuti mankhwalawa amawongolera momwe mankhwalawo amathandizira ndi mtima, amawonjezera mamvekedwe a mitsempha, amawongolera njira yodzaza mitsempha yamagazi ndi magazi, komanso amachepetsa mitsempha yaying'ono.

Kuyanjana kwa mankhwala osokoneza bongo

Bilobil sayenera kutumizidwa kwa odwala omwe amakonda kumwa mankhwala omwe amachepetsa magazi (mwachitsanzo, acetylsalicylic acid ndi mankhwala ena osapweteka a antiidal, othana ndi anticoagulants). Kuphatikiza koteroko kumatha kuchulukitsa chiopsezo chakutuluka kwa magazi chifukwa cha kuchuluka kwa nthawi yowundana.

Tidalemba ndemanga za anthu za mankhwala a Bilobil:

1. Chiyembekezo Pambuyo pakumalizidwa kwa ubongo ndi mitsempha yamagazi muubongo, Bilobil Forte adatumiza adotolo, amamwa pafupifupi chaka chathunthu ndipo samatha kumvetsetsa chifukwa chake kupanikizika kudakhala kotsika ndi 10070, ndipo kudachitika ngakhale kutsika, ndipo kugunda kwake kudumphira mpaka 120, adamva kuwawa kwambiri, kusiya kumwa ndipo pang'onopang'ono zonse zidayamba kuti mukhale bwino, kuti wina achiritsidwe ndi wina wolumala, muyenera kusamala kwambiri ndi mankhwalawa. Zaumoyo kwa onse.
2. Galina. Anamwa mwezi mwakhama, adachotsedwa ku khomo lachiberekero la cervical osteochondrosis. Mutuwu ndi mawonekedwe amaso, khungu. Sizinathandize konse.
3. Olga Ndidatenga makapisozi pambuyo povulala pamayendedwe a dokotala kuti andichotsere zotsalazo. "Bilobil" adathandizira kuchotsa tinnitus ndikuwongolera kukumbukira.
4. Zina. Kutsika mtengo sikutanthauza kukhala wabwinoko! Bilobil Intens 120mg: paketi ya makapisozi 60 imakhala ndi ma ruble 970, mtengo wa tanakan 40mg pama mapiritsi 90 a 1580, pamene tanakan sanandithandizire, ndipo Bilobil intens inakwera. Mavuto amakumbukiro amafuna yankho mu mankhwala apamwamba, odalirika. Kulimba mtima kwa Bilobil kunandichitira ndipo sindilinso ndi vuto la kukumbukira. Ndipo mutu suzungulira, sukupweteka. Koma chachikulu ndichakuti, ndikakhala ndi mutu womveka bwino ndizosavuta kugwira ntchito ndikuchita zinthu za tsiku ndi tsiku.
5. Olya. Ndinkamwa maphunziro a miyezi iwiri a bilobil. Kumva bwino. Mutu wanga unawala, ndikosavuta kuganiza, ndimakumbukira chilichonse ndipo sindisokoneza chilichonse. Zosakondweretsa monga chizungulire zapita, ndipo luso la kuzindikira lachuluka monga ubwana. Bilobil ndiwabwino kuposa mankhwala ambiri okhala ndi ginkgo, awa ndi mankhwala, osati oyipa, achilengedwe komanso amphamvu, chifukwa chake ndikumva bwino. Asanamwe kumwa ginkoom, koma sizinachitike. Pambuyo pa ginkoom, ndimadutsa zoyipa zonse. Ndipo Bilobil ndi mankhwala osokoneza bongo. Yofunika ndalamazo.

Madokotala ambiri amapereka umboni kuti kutulutsa mitengo ya ginkgo pafupifupi ndi mankhwala okhawo omwe amawongolera chidziwitso cha odwala okalamba. Komabe, kafukufuku adawonetsanso kuti atachotsa Bilobil mwa odwala am'gulu lino, kuyambiranso kwa zomwe zimayenderana ndi zaka.

Zofananira za mankhwalawa ndi mankhwala Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant ndi Tanakan.

Bilobil analogues ndi mankhwala monga:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memor
• Maruks
• Memantinol
• Memikar.

Musanagwiritse ntchito fanizo, funsani dokotala.

Zachipatala ndi gulu la mankhwala

Mankhwala omwe amapangitsa kuti magazi azisinthasintha.

Mankhwala Okhala Pamalo a Pharmacy

Amamasulidwa popanda kulandira mankhwala.

Kodi Bilobil ndi zingati? Mtengo wapakati pama pharmacies uli pamlingo wa ma ruble 550.

Kutulutsa mawonekedwe ndi kapangidwe kake

Chocolate bulau makapisozi. Makapisozi ali ndi ufa wofufuta wamtambo wokhala ndi tinthu tosalala tambiri.

• Kashiamu imodzi imakhala ngati yogwira ntchito: Kuuma kwa masamba a ginkgo biloba - 40 mg, wokhazikika kuti akhale ndi 9.6 mg wa flavono glycosides a ginkgo ndi 2.4 mg wa terpene lactones (ginkgolides ndi bilobalides) mu 40 mg.
• Zopatsa, lactose monohydrate, wowonda wa chimanga, talc, anhydrous colloidal silicon dioxide, magnesium stearate.
• Chigoba cha kapu: gelatin, indigotine (E132), azorubine (E122), oxide wofiira chitsulo * (E172), wakuda iron oxide (E 172), titanium dioxide (E 171).

Mankhwala

Bilobil ndi angioprotector wazomera zoyambira. Zotsatira zake, kuti kapangidwe kake ka mankhwalawa kamaphatikizira ginkgo biloba Tingafinye, monga terpene lactones ndi flavone glycosides, zida zake zogwiritsira ntchito kwachilengedwe zimalimbitsa kwambiri ndikuwonjezera kukondoweza kwa makoma amitsempha yamagazi, komanso kukonza kuthekera kwa magazi.

Malangizo a Bilobil amasonyezanso kuti mankhwalawa amawongolera momwe mankhwalawo amathandizira ndi mtima, amawonjezera mamvekedwe a mitsempha, amawongolera njira yodzaza mitsempha yamagazi ndi magazi, komanso amachepetsa mitsempha yaying'ono.

Zizindikiro zogwiritsidwa ntchito

Bilobil adalembedwa ma pathologies ambiri amanjenje, komanso zizindikiro ndi ma syndromes ambiri mwa iwo:

• Kuda nkhawa
• Tinnitus.
• Kusowa tulo
• Dyscirculatory encephalopathy, makamaka ndi kusazindikira kwanzeru.
• Chizungulire, makamaka chifukwa cha mtima zoyambitsa.
• Idachepetsa chidwi.

Bilobil itha kugwiritsidwanso ntchito mu zovuta kuchipatala pamaso pamavuto am'magazi am'munsi (machitidwe a angiosurgery).

Contraindication

Mankhwala nthawi zambiri amavomerezedwa ndi odwala, komabe, padera pokhapokha, izi zimadziwika:

• Kuchokera pakati mantha dongosolo: mutu, kuchuluka irritability.
• Thupi lawo siligwirizana: zotupa pakhungu, kuyabwa, urticaria, edema ya Quincke.
• Kuchokera mmimba: kukhumudwa, kusanza, kuphwanya chopondapo.

Ndi kukula kwambiri thupi lawo siligwirizana, kusiya mankhwala ndikofunikira.

Kupanga kwa zotsatira zoyipa kumawonedwa nthawi zambiri mukamamwa mankhwala a Bilobil Intens, komanso odwala okalamba omwe ali ndi Mlingo wambiri wa mankhwalawa.

Mimba komanso kuyamwa

Chifukwa cha kusowa kwa chidziwitso chokwanira chachipatala, Bilobil samalimbikitsidwa kuti azigwiritsa ntchito panthawi yomwe ali ndi pakati komanso poyamwitsa.

Malangizo ogwiritsira ntchito

Malangizo ogwiritsira ntchito akuwonetsa kuti Bilobil amatengedwa pakamwa. The kapisozi ayenera kumeza lonse ndi madzi pang'ono, ngakhale chakudya.

1. Dyscirculatory encephalopathy yamitundu yosiyanasiyana: 1-2 zisoti. Katatu / tsiku
2. Matenda a sensorineural (chizungulire, tinnitus, hypoacusia), senile macular degeneration, diabetesic retinopathy: 1 kapu. Katatu / tsiku
3. Kusokonezeka kwa kufalikira kwa magazi ndi zotumphukira (kuphatikiza miyendo ya m'munsi), matenda a Raynaud: 1 kapu. Katatu / tsiku

Zizindikiro zoyambira kusintha zimakonda kuonekera pambuyo pa mwezi umodzi. Njira ya chithandizo ndiosachepera miyezi itatu (makamaka kwa odwala okalamba). Njira yachiwiri ikhoza kuchitika atakambirana ndi dokotala.

Zotsatira zoyipa

Kumwa mankhwalawa kumatha kuyambitsa zotsatirazi: chizungulire, mseru, kusanza, kupweteka mutu, kutupa, kuyabwa, khungu, kuyabwa, kumva m'maso, kuona m'mimba thirakiti, kuchepa magazi, komanso kusowa tulo.

Nthawi zina, bilobil imatha kutulutsa magazi ndi kutaya magazi mu ubongo.Izi zimagwira ntchito makamaka ngati mankhwalawo atengedwa limodzi ndi othandizira magazi. Mwambiri, zoyipa za mankhwalawa zimawonedwa mosadukiza ndipo ndizakanthawi. Komabe, ngati zichitika, muyenera kufunsa dokotala.

Bongo

Ngati kuchuluka kwake kuchulukitsidwa, zomwe zimachitika mutakumana ndi zovuta zimatha. Mankhwalawa ndi achikhalidwe, kutengera zisonyezo.

Malangizo apadera

The achire zotsatira za mankhwalawa zimachitika pafupifupi mwezi umodzi kumwa mankhwalawo. Ngati munthawi ya mankhwalawa pakakhala kuwonongeka modzidzimutsa, kusowa kwa makutu, tinnitus kapena chizungulire kuwoneka, muyenera kusiya kumwa mankhwalawo ndikulakalaka upangireni dokotala.

Sitikulimbikitsidwa kusankha Bilobil kwa odwala omwe ali ndi galactose kapena glucose malabsorption syndrome, kobadwa nako galactosemia kapena kuperewera kwa lactase, chifukwa lactose ndi gawo limodzi la iwo.

Kuyanjana kwa mankhwala osokoneza bongo

Bilobil sayenera kutumizidwa kwa odwala omwe amakonda kumwa mankhwala omwe amachepetsa magazi (mwachitsanzo, acetylsalicylic acid ndi mankhwala ena osapweteka a antiidal, othana ndi anticoagulants). Kuphatikiza koteroko kumatha kuchulukitsa chiopsezo chakutuluka kwa magazi chifukwa cha kuchuluka kwa nthawi yowundana.

Tidalemba ndemanga za anthu za mankhwala a Bilobil:

1. Chiyembekezo Pambuyo pakumalizidwa kwa ubongo ndi mitsempha yamagazi muubongo, Bilobil Forte adatumiza adotolo, amamwa pafupifupi chaka chathunthu ndipo samatha kumvetsetsa chifukwa chake kupanikizika kudakhala kotsika ndi 10070, ndipo kudachitika ngakhale kutsika, ndipo kugunda kwake kudumphira mpaka 120, adamva kuwawa kwambiri, kusiya kumwa ndipo pang'onopang'ono zonse zidayamba kuti mukhale bwino, kuti wina achiritsidwe ndi wina wolumala, muyenera kusamala kwambiri ndi mankhwalawa. Zaumoyo kwa onse.
2. Galina. Anamwa mwezi mwakhama, adachotsedwa ku khomo lachiberekero la cervical osteochondrosis. Mutuwu ndi mawonekedwe amaso, khungu. Sizinathandize konse.
3. Olga Ndidatenga makapisozi pambuyo povulala pamayendedwe a dokotala kuti andichotsere zotsalazo. "Bilobil" adathandizira kuchotsa tinnitus ndikuwongolera kukumbukira.
4. Zina. Kutsika mtengo sikutanthauza kukhala wabwinoko! Bilobil Intens 120mg: paketi ya makapisozi 60 imakhala ndi ma ruble 970, mtengo wa tanakan 40mg pama mapiritsi 90 a 1580, pamene tanakan sanandithandizire, ndipo Bilobil intens inakwera. Mavuto amakumbukiro amafuna yankho mu mankhwala apamwamba, odalirika. Kulimba mtima kwa Bilobil kunandichitira ndipo sindilinso ndi vuto la kukumbukira. Ndipo mutu suzungulira, sukupweteka. Koma chachikulu ndichakuti, ndikakhala ndi mutu womveka bwino ndizosavuta kugwira ntchito ndikuchita zinthu za tsiku ndi tsiku.
5. Olya. Ndinkamwa maphunziro a miyezi iwiri a bilobil. Kumva bwino. Mutu wanga unawala, ndikosavuta kuganiza, ndimakumbukira chilichonse ndipo sindisokoneza chilichonse. Zosakondweretsa monga chizungulire zapita, ndipo luso la kuzindikira lachuluka monga ubwana. Bilobil ndiwabwino kuposa mankhwala ambiri okhala ndi ginkgo, awa ndi mankhwala, osati oyipa, achilengedwe komanso amphamvu, chifukwa chake ndikumva bwino. Asanamwe kumwa ginkoom, koma sizinachitike. Pambuyo pa ginkoom, ndimadutsa zoyipa zonse. Ndipo Bilobil ndi mankhwala osokoneza bongo. Yofunika ndalamazo.

Madokotala ambiri amapereka umboni kuti kutulutsa mitengo ya ginkgo pafupifupi ndi mankhwala okhawo omwe amawongolera chidziwitso cha odwala okalamba. Komabe, kafukufuku adawonetsanso kuti atachotsa Bilobil mwa odwala am'gulu lino, kuyambiranso kwa zomwe zimayenderana ndi zaka.

Zofananira za mankhwalawa ndi mankhwala Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant ndi Tanakan.

Bilobil analogues ndi mankhwala monga:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memor
• Maruks
• Memantinol
• Memikar.

Musanagwiritse ntchito fanizo, funsani dokotala.

Zosungirako ndi moyo wa alumali

Mankhwalawa ndi oyenera kugwiritsidwa ntchito zaka zitatu. Musapatse ana mwayi, muteteze ku kuwala. Kutentha kosungirako 200C.

Zachipatala ndi gulu la mankhwala

Inhibitor ya H + -K + -ATPase. Mankhwala a antiulcer

Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD

◊ Makapisozi obwera gelatin yolimba, kukula No. 3, yokhala ndi thupi loyera komanso chophimba cha buluu, zomwe zili m'mabotolowa ndizovala zazifupi kuyambira zoyera mpaka zoyera ndi zonona zonona kapena zachikasu.

* rabeprazole, pellet thunthu 8,5% - 118 mg.

Omwe amathandizira: magawo a shuga (sucrose - 99.83%, povidone - 0,17%) - 71.46 mg, sodium carbonate - 1.66 mg, talc - 1.77 mg, titanium dioxide - 0,83 mg, hypromellose - 14,75 mg.

Omwe amachokera ku chipolopolo: hypromellose phthalate - 15,94 mg, mowa wa cetyl - 1.59 mg.
The zikuchokera kapisozi zolimba gelatin No. 3: kapisozi thupi - titanium dioksidi - 2%, gelatin - mpaka 100%, kapisozi - titanium dioxide - 2%, utoto utoto utoto - 0,0176%, utoto wakuda wa diamondi - 0,0051%, gelatin - mpaka 100%.

Ma PC 5. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni. 7 ma PC. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni 10 ma PC. - mapaketi a matuza (1, 2, 3) - mapaketi a makatoni.

14 ma PC. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni. ma 15 ma PC. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni 20 ma PC. - mapaketi a matuza (1, 2, 3) - mapaketi a makatoni.

30 ma PC - mapaketi a matuza (1, 2, 3) - mapaketi a makatoni.

Pharmacokinetics

Zogulitsa ndi kugawa

Rabeprazole imatengedwa mwachangu kuchokera m'matumbo, Cmax m'magazi am'magazi amafikira pafupifupi maola 3.5 atatha kutumikiridwa pa mlingo wa 20 mg. Kusintha kwa Cmax mu plasma yamagazi, mfundo za AUC za rabeprazole ndizofanana pamlingo wambiri kuchokera 10 mpaka 40 mg.

Mtheradi bioavailability pambuyo m`kamwa makonzedwe pa 20 mg (poyerekeza iv) pafupifupi 52%. Kuphatikiza apo, bioavailability sasintha ndi Mlingo wambiri wa rabeprazole. Ngakhale nthawi yomwe mankhwalawa amamwa mankhwalawa masana, kapena makonzedwe omwewo munthawi yomweyo samakhudza mayamwidwe a rabeprazole.

Kutenga mankhwalawa ndi zakudya zamafuta kumachepetsa kuyamwa kwa rabeprazole kwa maola 4 kapena kupitilira apo, komabe, Cmax kapena kuchuluka kwa mayamwidwe sikusintha.

Kumangidwa kwa rabeprazole ku mapuloteni a plasma kuli pafupifupi 97%.

Kutetemera ndi chimbudzi

Metabolite yayikulu ndi thioether (M1). Metabolite yokhayo yomwe imagwira ntchito ndi desmethyl (M3), komabe, idatsimikizika mu ndende zochepa m'mgulu limodzi lomwe limatenga nawo kafukufuku wa rabeprazole pa 80 mg.

Mlingo umodzi wa 14C wolembedwa kuti rabeprazole sodium pa 20 mg, mankhwala osasinthika sanapezeke mkodzo.

Pafupifupi 90% ya rabeprazole imachotseredwa kudzera mu impso makamaka mwa ma metabolites awiri: conjugate ya mercapturic acid (M5) ndi carboxylic acid (M6), komanso mawonekedwe a metabolites awiri osadziwika omwe adadziwika pakuwunikira kwa sumu. Sodium yotsalira ya rabeprazole yotengedwa imatuluka m'matumbo.

Kuchotsa kwathunthu ndi 99.8%. Izi zimawonetsa kachulukidwe kakang'ono ka rabeprazole sodium metabolites ndi bile.

M'magulu odzipereka athanzi, plasma T1 / 2 ili pafupifupi ola limodzi (kuyambira 0,7 mpaka 1.5 maola), ndipo chilolezo chonse ndi 3.8 ml / min / kg.

Pharmacokinetics pamagulu apadera a odwala

Odwala omwe ali ndi chiwindi chambiri, AUC imachulukitsidwa kawiri poyerekeza ndi odzipereka athanzi, zomwe zimawonetsa kuchepa kwa metabolism panthawi ya "pass yoyamba", ndipo T1 / 2 kuchokera ku plasma yamagazi imachulukitsidwa katatu.

Odwala okhazikika kumapeto kwa gawo aimpso kulephera amene amafuna kukonza hemodialysis (CC

• Makapu amodzi a Bilobil ali ndi 40 mg kuchokera ku masamba a mtengo ginkgo-masamba awiri.
• Kapu imodzi imodzi ya Bilobil Forte imaphatikizapo 80 mg kuchokera kwa masamba a mtengo ginkgo-masamba awiri.

100 mg ya Tingafinye timaphatikizapo 19.2 mg ginkgo glycosides mtundu wa flavone ndi 4.

8 mg miyala ya terpene lembani (bilobalides ndi ginkgolides).

Zowonjezera: colloidal silicon oxide, wowuma chimanga, lactose monohydrate, magnesium stearate, talc.

Mapangidwe a Shell: utoto wofiira wachitsulo, titanium dioxide, azorubine, utoto wakuda zitsulo, gelatin.

Mankhwala

Phytopreparation, normalizing kagayidwe m'maselo rheological Zizindikiro magazi ndi minofu mafuta.

Zimasintha kufalikira kwa ziwalo za m'magazi ndipo zimapatsa ubongo shuga ndi mpweyaamalepheretsa kuphatikizika maselo ofiira amwaziimachepetsa kutsegulira kuchuluka kwa mapulateleti.

Amakhala ndi amadalira mlingo wa mtima pa mtima, amathandizira kupanga AYI, imakulitsa kuunikira kwa ma arterioles, kumawonjezera mamvekedwe a mitsempha, potero kusintha kusintha kwa mitsempha yamagazi. Imafooketsa kutsika kwa khoma la chotengera.

Zinthu antithrombotic zochita (kumalimbitsa zimimba za maselo ofiira am'magazi ndi mapulateleti, zimakhudza biosynthesis ma prostaglandinsImafooketsa zotsatira kuphatikiza mapulateleti) Zimalepheretsa peroxidation wamafuta a zimagwira ma cell ndikumapangidwa kwa ma free radicals.

Matenda a metabolism ma neurotransmitters (monga dopamine, norepinephrine ndi acetylcholine) Ndiponso antihypoxic kuchitapo, kumapangitsa kagayidwe, kumalimbikitsa kudziunjikira macroergsimathandizira kutaya shuga ndi mpweyaamawongolera njira zoyimira pakati mu ubongo.

Zotsatira zoyipa

Kuchepa kwa chakudya, nseru, m'mimba kupweteka, zimbudzi zamkati, kulawa kwazitsulo mkamwa, lactic acidosis.

Kuchita

Zotsatira zimachepetsedwa ndi corticosteroids.

Mlingo ndi makonzedwe

Mkati, 1 tebulo. 2 katatu tsiku lililonse mukatha kudya. Pazipita tsiku lililonse 300 mg mu 3 4 waukulu.

Njira zopewera kupewa ngozi

Chenjezo liyenera kuperekedwa limodzi ndi okodzetsa (makamaka ndi zotumphukira za thiazide).

Chifukwa cha chiwopsezo cha lactic acidosis, kuyezetsa magazi kuyenera kuchitidwa miyezi isanu ndi umodzi iliyonse, ndipo ntchito ya chiwindi ndi impso iyenera kuyang'aniridwa. Pamaso pa opareshoni, kusintha kwa insulini ndikofunikira.

Pa chithandizo, simungamwe mowa, chifukwa Nthawi zina, mowa ungachitike.

Kusungidwa kwa mankhwala a Adebit

Kutentha kwanyumba.

Pewani kufikira ana.

Alumali moyo wa mankhwala Adebit

Mafotokozedwe a magulu a nosological

Malangizo a Glibutide, ndemanga, mtengo, kufotokoza

Dzinalo:

Machitidwe

Ndi gawo la mankhwala omwe amapezeka pakamwa a hypoglycemic (antidiabetesic) (makonzedwe amkamwa omwe amachepetsa shuga la magazi) a gulu la Biguanide.

Glibutide, monga ma biguanides ena, amatanthauza mankhwala opatsirana a pakamwa omwe amachititsa kuchepetsa kwambiri odwala m'thupi la odwala matenda ashuga.

Mankhwalawa amachepetsa chilimbikitso, amalimbikitsa anaerobic glycolysis (kupanga mphamvu mu khungu popanda kutengapo gawo la okosijeni), kuchepetsa kuyamwa kwa glucose kuchokera m'matumbo am'mimba, kukhala ndi antilipid (kutsitsa mafuta) ndi fibinolytic effect (kuvunda kwa magazi a magazi).

Zizindikiro zogwiritsidwa ntchito:

Amagwiritsidwa ntchito pofuna kuchiza matenda a shuga II mellitus (insulin-Independent) mwa akulu.

Kuphatikiza ndi insulin, imagwiritsidwa ntchito ngati mitundu ya insulin yolimbana ndi matenda ashuga (shuga, yolimbana ndi mankhwala okonzekera insulin), komanso kukana (kukana) mankhwala opatsirana a sulfonylurea, chifukwa cha mitundu yovuta ya shuga, yothandizidwa ndi kunenepa kwambiri, komanso odwala omwe akulandira chithandizo cha insulin matenda ashuga (shuga mellitus, amadziwika ndi kusintha kwachilengedwe m'magazi).

Njira Yogwiritsira Ntchito:

Gawani mkati ndi chakudya.

Monga othandizira odwala matenda ashuga, tengani, kuyambira pa 0,1 ga patsiku (50 mg m'mawa ndi madzulo), kutengera kusintha kwa shuga m'magazi ndi mkodzo, mlingo umatha kuwonjezeka pang'onopang'ono ndi 50 mg patsiku, koma tsiku lililonse mlingo sayenera kupitirira 300 mg

Mlingo wokonza nthawi zambiri umakhala 50-100 mg m'mawa ndi 50 mg madzulo.Pamaphatikizidwa ndi insulin, mlingo wotsiriza umachepetsedwa motsogozedwa ndi shuga m'magazi ndi mkodzo.

Pamodzi ndi kukonzekera kwa sulfonylurea, glibutide imalembedwa pokhapokha woyamba atalephera kuchepetsa hyperglycemia (kuchuluka kwa shuga m'magazi) ndi glucosuria (kukhalapo kwa shuga mumkodzo) mpaka muyezo wofunikira. kuphatikiza ndi anorexigenic / chilakolako kuponderezana / mankhwala).

Mapiritsi okhala ndi nthawi yayitali amapatsidwa piritsi limodzi (m'mawa), ndikukulitsa pang'onopang'ono mapiritsi 4 (m'mawa ndi madzulo mutatha kudya).

Zochitika:

Glibutide imalekereredwa bwino, koma kutaya mtima, kusanza, kusanza, kutsekula m'mimba (m'mimba), ndi kutsekemera kwazitsulo mkamwa kumatha kuonedwa. Tsiku lotsatira kuyambira pa chiyambi cha chithandizo (pambuyo pa mwezi kapena kupitirira), kufooka, kuchepa thupi kumatheka.

Zotsatira zoyipa zimachoka mwachangu ndi kuchepetsedwa kwa mankhwala kapena kusiya mankhwala.

Zoyipa:

Zotsatira zamagwiritsidwe ntchito a glibutide ndi: Zizindikiro zakugwiritsira ntchito insulin, kusowa kwa thupi la amkati (opangidwa m'thupi) kapena kutumikiridwa kwathunthu (kunja) insulin, chikomokere (kutaya chikumbumtima, chodziwika ndi kusapezeka kwathunthu kwa zomwe thupi limachita pazosintha zakunja), acidosis (acidization), matenda opatsirana, albuminuria (mapuloteni mu mkodzo) chifukwa cha matenda ashuga nephropathy (kuwonongeka kwa mitsempha yamagazi ndi minyewa yamatenda a shuga mellitus), kuwonongeka kwa chiwindi, angiopathy ya matenda ashuga Mitsempha yamitsempha yamitsempha yokhudzana ndi shuga wambiri) ndikuthekera kotupa, matenda am'mimba, mimba. Tiyenera kukumbukira kuti odwala ena amatha kupanga ketosis ndi glibutide (acidization chifukwa cha kuchuluka kwa matupi a ketone m'magazi - mankhwala apakatikati kagayidwe kachakudya) ndi kuchepa kwa magazi osungidwa m'magazi (magwiridwe amachitidwe a magazi othandizira magazi, omwe amalepheretsa kusintha kwa pH).

Pankhani ya ketosis, mankhwalawa amatha. Mukamachiza ndi glibutide, makamaka nthawi yoyambayo, ndikofunikira kuyang'ana mkodzo kuti muone zomwe zili mu acetone momwemo. M'tsogolomu, kutsimikiza kwa matupi a ketone (mankhwala apakatikati) kumachitika pafupifupi nthawi imodzi pa sabata.

Fomu yotulutsa katundu:

Mapiritsi a 0,05 g mu phukusi la zidutswa 50. Mapiritsi okhala ndi nthawi yayitali a buformin retard.

Malo osungira:

Mankhwalawa amachokera mndandanda B. Pamalo pouma.

Buformin hydrochloride, Adebit, Butyl biguanide, Gliporal, Glibigid hydrochloride, Krebon, Silubin.

Butylbiguanide hydrochloride. White crystalline ufa wowawa.Piritsi losungunuka m'madzi ndi moledzera. Piritsi limodzi lokhala ndi nthawi yayitali limakhala ndi: 0.17 g ya buformin tosylate, yomwe imafanana ndi 0,1 g yogwira ntchito (glibutide).

Kukonzekera kofananako:

Diaformin (Diaformin) Glucovans (Glucovance) Oltar (Oltar) Glyukofazh (Glucophage) Maninil (Maninil)

Sanapeze zomwe mukufuna?
Malangizo onse amomwe mankhwalawa "glibutide" angapezeke pano:

Madokotala okondedwa!

Ngati mukumva kuperekera mankhwala kwa odwala anu - gawani zotsatira (kusiya ndemanga)! Kodi mankhwalawa adathandizira wodwala, kodi panali zotsatirapo zilizonse zomwe zimachitika panthawi ya chithandizo? Zomwe mukuwona zidzakhala zosangalatsa kwa anzanu komanso odwala.

Okondedwa odwala!

Ngati mankhwalawa adakulangizani inu ndipo mwalandira chithandizo chamankhwala, ndiwuzeni ngati chinali chothandiza (ngakhale chinathandizapo), ngakhale panali zovuta, zomwe mumakonda / zomwe simunazikonde. Anthu zikwizikwi akufuna kuyang'ana pa intaneti zamankhwala osiyanasiyana. Koma ochepa okha ndi omwe amawasiya. Ngati inu panokha simusiya ndemanga pamutuwu - ena onse sangakhale ndi zomwe angawerenge.

Zikomo kwambiri!/ sitemap-index.xml

Kufotokozera za mankhwala "Adebit"

Machitidwe a pharmacological Amachepetsa shuga m'magazi ndikusinthasintha kwake tsiku ndi tsiku, kufunika kwa insulin.

Zizindikiro zogwiritsidwa ntchito

• Type II shuga mellitus (kuphatikiza ndi mankhwala a sulfonylurea), kunenepa kwambiri kwa shuga, shuga wosakhazikika (kuphatikiza ndi insulin).

• 50 mg mapiritsi
• matuza 20, bokosi (bokosi) 2.

Pharmacodynamics wa mankhwala Hypoglycemic wothandizira pakamwa makonzedwe kuchokera pagulu la biguanides. Imagwira mwachindunji mphamvu ya anaerobic glycolysis mu zotumphukira zimakhala.

Amachepetsa gluconeogenesis m'chiwindi, amachepetsa mayamwidwe am'mimba kuchokera m'matumbo am'mimba (amalepheretsa matumbo alpha-glycosidases, amachepetsa kuphwanya kwa enzymatic kwa di-, oligo- ndi polysaccharides kwa monosaccharides), amachepetsa chilimbikitso.

Imachepetsa mphamvu ya plasma glucagon, imawonjezera chidwi cha zimakhala kuti insulin ikumangiriza insulini kupita ku insulin receptors. Kukhazikika kwa zochita kumachitika pambuyo pa maola 2-4, nthawi yochitapo kanthu ili pafupifupi maola 8.

Contraindication

• Hypersensitivity, ketonuria, hyperglycemic chikomokere, hypoglycemia, pakati, mkaka wa m`mawere. Lactic acidosis (kuphatikizapo mbiri)
• hepatic ndi / kapena aimpso kulephera, mtima kulephera, kupuma, infarction pachimake, uchidakwa, malungo, matenda opatsirana, albuminuria motsutsana ndi matenda a matenda a shuga.

Zotsatira zoyipa: Kuchepa kwa chakudya, nseru, kusanza, kufooka, kuchepa thupi, matenda am'mimba, m'mimba, kulawa kwamkati ndi zitsulo.

Mlingo Mkati, piritsi limodzi. Katatu patsiku mutatha kudya. Pazipita tsiku mlingo 300 mg mu 3-4 waukulu.

Zizindikiro za bongo: hypoglycemia, hypoglycemic coma.

Kugwirizana ndi mankhwala ena Mphamvu ya hypoglycemic imafooketsedwa ndi zotumphukira za phenothiazine, corticosteroids, mahomoni olimbikitsa a chithokomiro, estrogens, okodzetsa, Mao zoletsa, ma salicylates.

Malangizo apadera a kuvomerezedwa Ndikofunika kuwunika pafupipafupi kuchuluka kwa shuga mumkodzo, mulingo wa glycemia. Mukamalowa mankhwalawa ndi buformin, mlingo wa insulin umachepetsedwa pang'onopang'ono.

Mndandanda B

Alumali moyo miyezi 60.

Maphunziro a matenda

Matenda a shuga osagwirizana ndi insulin

Gulu la ophunzira la ATX (ATC)

Kutaya chakudya thirakiti ndi kagayidwe

Zotsatira za pharmacological

Kufotokozera Hypoglycemic zotsatira zake kumachepetsa misempha yamagazi. Limagwirira ntchito amatengera kumangiriza insulin kwa zolandilira zake, potero zimakhudza kagayidwe kachakudya shuga.

Zotsatira zake, kuchuluka kwa glucose m'magazi kumachepetsedwa chifukwa chowonjezereka pakugwiritsa ntchito kwake mu minofu yapaziphuphu, makamaka minofu yamatumbo ndi minofu ya adipose, komanso kuletsa mapangidwe a shuga mu chiwindi.

Kuphatikiza pa chiwongolero cha insulin, momwe amagwirira ntchito zimagwirizanitsidwa ndi kukondoweza kwa mapangidwe?

Komanso makina ochitapo kanthu amatha kuphatikizidwa ndi kulepheretsa kwa gluconeogeneis m'chiwindi (kuphatikiza glycogenolysis) ndikuwonjezera kugwiritsidwa ntchito kwa glucose pogwiritsa ntchito zotumphukira, kulepheretsa insulin kutulutsa ndi kusintha kwa kumangiriza kwake kwa insulin receptors (izi zimakulitsa kupezeka kwa glucose ndi metabolism yake).

Chimodzi mwazinthu zomwe zikuchitika ndikuchepetsa insulin kukokana ndi zotumphukira ndi chiwindi. Kulepheretsa kwa kuwonongeka kwa poly- ndi oligosaccharides ndikotheka, komwe kumachepetsa mapangidwe a shuga m'matumbo, potero kuletsa kukula kwa postprandial hyperglycemia. Mankhwala a Hypoglycemic amagwiritsidwa ntchito pochiza matenda ashuga.

Gulu la mankhwala

Kupanga kwa Hypoglycemic ndi othandizira ena

Zinthu zogwira ntchito

Kufotokozera White crystalline ufa wowawa. Sungunuka mosavuta m'madzi ndi mowa.

Zomwe zimaperekedwa ndizothandiza kudziwa zambiri.
Musanagwiritse ntchito, chonde funsani katswiri.

Zomwe zimathandiza Bilobil: malangizo ndi kuwunika

Mankhwala achilengedwe a Bilobil ndi omwe amapanga maganizo.

Cholinga chake ndikuwongolera magwiridwe antchito a ubongo ndi machitidwe amanjenje. Amapangidwa pamaziko a mbewu zam'magazi olimbitsa thupi kuchokera ku gulu la maginki awiri. Mitundu iyi ya conifers imachokera kum'mawa kwa China, koma imalimidwa m'minda yambiri padziko lapansi.

Patsambali mupezapo zambiri zokhudzana ndi Bilobil: Malangizo onse omwe mungagwiritsire ntchito mankhwalawa, mitengo ya mankhwala, mankhwala, ndemanga zathunthu komanso zosakwanira, komanso ndemanga za anthu omwe amagwiritsa ntchito Bilobil kale. Mukufuna kusiya malingaliro anu? Chonde lembani ndemanga.

Zachipatala ndi gulu la mankhwala

Mankhwala omwe amapangitsa kuti magazi azisinthasintha.

Mankhwala Okhala Pamalo a Pharmacy

Amamasulidwa popanda kulandira mankhwala.

Kodi Bilobil ndi zingati? Mtengo wapakati pama pharmacies uli pamlingo wa ma ruble 550.

Kutulutsa mawonekedwe ndi kapangidwe kake

Chocolate bulau makapisozi. Makapisozi ali ndi ufa wofufuta wamtambo wokhala ndi tinthu tosalala tambiri.

• Kashiamu imodzi imakhala ngati yogwira ntchito: Kuuma kwa masamba a ginkgo biloba - 40 mg, wokhazikika kuti akhale ndi 9.6 mg wa flavono glycosides a ginkgo ndi 2.4 mg wa terpene lactones (ginkgolides ndi bilobalides) mu 40 mg.
• Zopatsa, lactose monohydrate, wowonda wa chimanga, talc, anhydrous colloidal silicon dioxide, magnesium stearate.
• Chigoba cha kapu: gelatin, indigotine (E132), azorubine (E122), oxide wofiira chitsulo * (E172), wakuda iron oxide (E 172), titanium dioxide (E 171).

Mankhwala

Bilobil ndi angioprotector wazomera zoyambira. Zotsatira zake, kuti kapangidwe kake ka mankhwalawa kamaphatikizira ginkgo biloba Tingafinye, monga terpene lactones ndi flavone glycosides, zida zake zogwiritsira ntchito kwachilengedwe zimalimbitsa kwambiri ndikuwonjezera kukondoweza kwa makoma amitsempha yamagazi, komanso kukonza kuthekera kwa magazi.

Malangizo a Bilobil amasonyezanso kuti mankhwalawa amawongolera momwe mankhwalawo amathandizira ndi mtima, amawonjezera mamvekedwe a mitsempha, amawongolera njira yodzaza mitsempha yamagazi ndi magazi, komanso amachepetsa mitsempha yaying'ono.

Zizindikiro zogwiritsidwa ntchito

Bilobil adalembedwa ma pathologies ambiri amanjenje, komanso zizindikiro ndi ma syndromes ambiri mwa iwo:

• Kuda nkhawa
• Tinnitus.
• Kusowa tulo
• Dyscirculatory encephalopathy, makamaka ndi kusazindikira kwanzeru.
• Chizungulire, makamaka chifukwa cha mtima zoyambitsa.
• Idachepetsa chidwi.

Bilobil itha kugwiritsidwanso ntchito mu zovuta kuchipatala pamaso pamavuto am'magazi am'munsi (machitidwe a angiosurgery).

Contraindication

Mankhwala nthawi zambiri amavomerezedwa ndi odwala, komabe, padera pokhapokha, izi zimadziwika:

• Kuchokera pakati mantha dongosolo: mutu, kuchuluka irritability.
• Thupi lawo siligwirizana: zotupa pakhungu, kuyabwa, urticaria, edema ya Quincke.
• Kuchokera mmimba: kukhumudwa, kusanza, kuphwanya chopondapo.

Ndi kukula kwambiri thupi lawo siligwirizana, kusiya mankhwala ndikofunikira.

Kupanga kwa zotsatira zoyipa kumawonedwa nthawi zambiri mukamamwa mankhwala a Bilobil Intens, komanso odwala okalamba omwe ali ndi Mlingo wambiri wa mankhwalawa.

Mimba komanso kuyamwa

Chifukwa cha kusowa kwa chidziwitso chokwanira chachipatala, Bilobil samalimbikitsidwa kuti azigwiritsa ntchito panthawi yomwe ali ndi pakati komanso poyamwitsa.

Malangizo ogwiritsira ntchito

Malangizo ogwiritsira ntchito akuwonetsa kuti Bilobil amatengedwa pakamwa. The kapisozi ayenera kumeza lonse ndi madzi pang'ono, ngakhale chakudya.

1. Dyscirculatory encephalopathy yamitundu yosiyanasiyana: 1-2 zisoti. Katatu / tsiku
2. Matenda a sensorineural (chizungulire, tinnitus, hypoacusia), senile macular degeneration, diabetesic retinopathy: 1 kapu. Katatu / tsiku
3. Kusokonezeka kwa kufalikira kwa magazi ndi zotumphukira (kuphatikiza miyendo ya m'munsi), matenda a Raynaud: 1 kapu. Katatu / tsiku

Zizindikiro zoyambira kusintha zimakonda kuonekera pambuyo pa mwezi umodzi. Njira ya chithandizo ndiosachepera miyezi itatu (makamaka kwa odwala okalamba). Njira yachiwiri ikhoza kuchitika atakambirana ndi dokotala.

Zotsatira zoyipa

Kumwa mankhwalawa kumatha kuyambitsa zotsatirazi: chizungulire, mseru, kusanza, kupweteka mutu, kutupa, kuyabwa, khungu, kuyabwa, kumva m'maso, kuona m'mimba thirakiti, kuchepa magazi, komanso kusowa tulo.

Nthawi zina, bilobil imatha kutulutsa magazi ndi kutaya magazi mu ubongo. Izi zimagwira ntchito makamaka ngati mankhwalawo atengedwa limodzi ndi othandizira magazi. Mwambiri, zoyipa za mankhwalawa zimawonedwa mosadukiza ndipo ndizakanthawi. Komabe, ngati zichitika, muyenera kufunsa dokotala.

Bongo

Ngati kuchuluka kwake kuchulukitsidwa, zomwe zimachitika mutakumana ndi zovuta zimatha. Mankhwalawa ndi achikhalidwe, kutengera zisonyezo.

Malangizo apadera

The achire zotsatira za mankhwalawa zimachitika pafupifupi mwezi umodzi kumwa mankhwalawo. Ngati munthawi ya mankhwalawa pakakhala kuwonongeka modzidzimutsa, kusowa kwa makutu, tinnitus kapena chizungulire kuwoneka, muyenera kusiya kumwa mankhwalawo ndikulakalaka upangireni dokotala.

Sitikulimbikitsidwa kusankha Bilobil kwa odwala omwe ali ndi galactose kapena glucose malabsorption syndrome, kobadwa nako galactosemia kapena kuperewera kwa lactase, chifukwa lactose ndi gawo limodzi la iwo.

Kuyanjana kwa mankhwala osokoneza bongo

Bilobil sayenera kutumizidwa kwa odwala omwe amakonda kumwa mankhwala omwe amachepetsa magazi (mwachitsanzo, acetylsalicylic acid ndi mankhwala ena osapweteka a antiidal, othana ndi anticoagulants). Kuphatikiza koteroko kumatha kuchulukitsa chiopsezo chakutuluka kwa magazi chifukwa cha kuchuluka kwa nthawi yowundana.

Tidalemba ndemanga za anthu za mankhwala a Bilobil:

1. Chiyembekezo Pambuyo pakumalizidwa kwa ubongo ndi mitsempha yamagazi muubongo, Bilobil Forte adatumiza adotolo, amamwa pafupifupi chaka chathunthu ndipo samatha kumvetsetsa chifukwa chake kupanikizika kudakhala kotsika ndi 10070, ndipo kudachitika ngakhale kutsika, ndipo kugunda kwake kudumphira mpaka 120, adamva kuwawa kwambiri, kusiya kumwa ndipo pang'onopang'ono zonse zidayamba kuti mukhale bwino, kuti wina achiritsidwe ndi wina wolumala, muyenera kusamala kwambiri ndi mankhwalawa. Zaumoyo kwa onse.
2. Galina. Anamwa mwezi mwakhama, adachotsedwa ku khomo lachiberekero la cervical osteochondrosis. Mutuwu ndi mawonekedwe amaso, khungu.Sizinathandize konse.
3. Olga Ndidatenga makapisozi pambuyo povulala pamayendedwe a dokotala kuti andichotsere zotsalazo. "Bilobil" adathandizira kuchotsa tinnitus ndikuwongolera kukumbukira.
4. Zina. Kutsika mtengo sikutanthauza kukhala wabwinoko! Bilobil Intens 120mg: paketi ya makapisozi 60 imakhala ndi ma ruble 970, mtengo wa tanakan 40mg pama mapiritsi 90 a 1580, pamene tanakan sanandithandizire, ndipo Bilobil intens inakwera. Mavuto amakumbukiro amafuna yankho mu mankhwala apamwamba, odalirika. Kulimba mtima kwa Bilobil kunandichitira ndipo sindilinso ndi vuto la kukumbukira. Ndipo mutu suzungulira, sukupweteka. Koma chachikulu ndichakuti, ndikakhala ndi mutu womveka bwino ndizosavuta kugwira ntchito ndikuchita zinthu za tsiku ndi tsiku.
5. Olya. Ndinkamwa maphunziro a miyezi iwiri a bilobil. Kumva bwino. Mutu wanga unawala, ndikosavuta kuganiza, ndimakumbukira chilichonse ndipo sindisokoneza chilichonse. Zosakondweretsa monga chizungulire zapita, ndipo luso la kuzindikira lachuluka monga ubwana. Bilobil ndiwabwino kuposa mankhwala ambiri okhala ndi ginkgo, awa ndi mankhwala, osati oyipa, achilengedwe komanso amphamvu, chifukwa chake ndikumva bwino. Asanamwe kumwa ginkoom, koma sizinachitike. Pambuyo pa ginkoom, ndimadutsa zoyipa zonse. Ndipo Bilobil ndi mankhwala osokoneza bongo. Yofunika ndalamazo.

Madokotala ambiri amapereka umboni kuti kutulutsa mitengo ya ginkgo pafupifupi ndi mankhwala okhawo omwe amawongolera chidziwitso cha odwala okalamba. Komabe, kafukufuku adawonetsanso kuti atachotsa Bilobil mwa odwala am'gulu lino, kuyambiranso kwa zomwe zimayenderana ndi zaka.

Zofananira za mankhwalawa ndi mankhwala Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant ndi Tanakan.

Bilobil analogues ndi mankhwala monga:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memor
• Maruks
• Memantinol
• Memikar.

Musanagwiritse ntchito fanizo, funsani dokotala.

Zosungirako ndi moyo wa alumali

Mankhwalawa ndi oyenera kugwiritsidwa ntchito zaka zitatu. Musapatse ana mwayi, muteteze ku kuwala. Kutentha kosungirako 200C.

Zachipatala ndi gulu la mankhwala

Inhibitor ya H + -K + -ATPase. Mankhwala a antiulcer

Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD

◊ Makapisozi obwera gelatin yolimba, kukula No. 3, yokhala ndi thupi loyera komanso chophimba cha buluu, zomwe zili m'mabotolowa ndizovala zazifupi kuyambira zoyera mpaka zoyera ndi zonona zonona kapena zachikasu.

* rabeprazole, pellet thunthu 8,5% - 118 mg.

Omwe amathandizira: magawo a shuga (sucrose - 99.83%, povidone - 0,17%) - 71.46 mg, sodium carbonate - 1.66 mg, talc - 1.77 mg, titanium dioxide - 0,83 mg, hypromellose - 14,75 mg.

Omwe amachokera ku chipolopolo: hypromellose phthalate - 15,94 mg, mowa wa cetyl - 1.59 mg.
The zikuchokera kapisozi zolimba gelatin No. 3: kapisozi thupi - titanium dioksidi - 2%, gelatin - mpaka 100%, kapisozi - titanium dioxide - 2%, utoto utoto utoto - 0,0176%, utoto wakuda wa diamondi - 0,0051%, gelatin - mpaka 100%.

Ma PC 5. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni. 7 ma PC. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni 10 ma PC. - mapaketi a matuza (1, 2, 3) - mapaketi a makatoni.

14 ma PC. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni. ma 15 ma PC. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni 20 ma PC. - mapaketi a matuza (1, 2, 3) - mapaketi a makatoni.

30 ma PC - mapaketi a matuza (1, 2, 3) - mapaketi a makatoni.

Zotsatira za pharmacological

Inhibitor ya H + -K + -ATPase. Mankhwala a antiulcer.

Sodium ya Rabeprazole ndi ya gulu la mankhwala antisecretory ochokera ku benzimidazole. Sodium ya Rabeprazole imalepheretsa kubisika kwa madzi am'mimba mwachangu poletsa H + / K + -ATPase pazinsinsi za maselo a parietal m'mimba.

H + / K + -ATPase ndi mapuloteni ovuta omwe amagwira ntchito ngati pampu ya proton, motero rabeprazole sodium ndi cholepheretsa pampu ya proton m'mimba ndikutseka gawo lomaliza la asidi.

Izi zimadalira mlingo ndipo zimatsogolera kukaponderezedwa kwa zonse zoyambira komanso kusungidwa kwa secretion wa asidi, mosasamala kanthu za zotsitsimutsa. Sodium ya Rabeprazole ilibe katundu wa anticholinergic.

Pambuyo pakamwa makonzedwe a rabeprazole sodium pa 20 mg, antisecretory effect imayamba mkati mwa ola limodzi.Kuletsa kwapansi ndi kusungunuka kwa asidi patsekeke patatha maola 23 mutatenga koyamba muyezo wa rabeprazole sodium ndi 69% ndi 82%, motero, ndipo kumatenga mpaka maola 48.

Kutalika kwa nthawi ya pharmacodynamic zochita kumapitilira zomwe zinanenedweratu ndi T1 / 2 (pafupifupi ola limodzi). Izi zitha kufotokozedwa ndi kumangidwa kwa mankhwala kwa nthawi yayitali kwa H + / K + -ATPase ya maselo a parietal m'mimba.

Ubwino wa inhibitory mphamvu ya rabeprazole sodium pa asidi secretion umafika pagome patatha masiku atatu atamwa rabeprazole sodium. Mukasiya kutenga ntchito zachinsinsi imabwezeretsedwa mkati mwa masiku 1-2.

Zokhudza kuchuluka kwa gastrin m'magazi

M'mayesero azachipatala, odwala adatenga rabeprazole sodium mu Mlingo wa 10 kapena 20 mg tsiku lililonse kwa nthawi yayitali ya miyezi 43. The kuchuluka kwa gastrin mu madzi am`magazi anachulukitsidwa kwa masabata 2-8 oyamba, zomwe zimawonetsa kulepheretsa kwapadera kwa asidi. The kuchuluka kwa gastrin kubwerera kwawo koyambirira nthawi zambiri mkati mwa masabata 1-2 atasiya kulandira chithandizo.

Zotsatira zamaselo ofanana ndi a enterochromaffin

Mukamayang'ana zitsanzo zam'mimba za munthu kuchokera pansi pa mmimba ndi pansi pamimba, odwala 500 omwe adalandira rabeprazole sodium kapena mankhwala osiyanitsa kwa masabata 8, kusintha kosasintha kwa maselo a cell of enterochromin, kukula kwa gastritis, kuchuluka kwa atrophic gastritis, metaplasia wamatumbo kapena kufalikira kwa Helicobacter. wapeza.

Pakufufuza kwa odwala oposa 400 omwe adalandira rabeprazole sodium (10 mg / tsiku kapena 20 mg / tsiku) kwa chaka chimodzi, zochitika za hyperplasia zinali zochepa komanso zofanana ndi zomwe zimachitika mu omeprazole (20 mg / kg). Panalibe milandu yovuta kusintha kapena zotupa zama carcinoid zomwe zimadziwika m'makola.

Zotsatira zamachitidwe a rabeprazole sodium mogwirizana ndi dongosolo lamkati lamanjenje, mtima kapena kupuma pakadali pano sizinapezeke.

Zinawonetsedwa kuti sodium ya rabeprazole, ikamamwa pakamwa 20 mg kwa masabata awiri, sizikhudza ntchito ya chithokomiro, kuchuluka kwa kagayidwe kamwazi m'magazi, komanso kuchuluka kwa cortisol, estrogen, testosterone, prolactin, glucagon, FSH, LH , renin, aldosterone ndi mahomoni okula.

Pharmacokinetics

Zogulitsa ndi kugawa

Rabeprazole imatengedwa mwachangu kuchokera m'matumbo, Cmax m'magazi am'magazi amafikira pafupifupi maola 3.5 atatha kutumikiridwa pa mlingo wa 20 mg. Kusintha kwa Cmax mu plasma yamagazi, mfundo za AUC za rabeprazole ndizofanana pamlingo wambiri kuchokera 10 mpaka 40 mg.

Mtheradi bioavailability pambuyo m`kamwa makonzedwe pa 20 mg (poyerekeza iv) pafupifupi 52%. Kuphatikiza apo, bioavailability sasintha ndi Mlingo wambiri wa rabeprazole. Ngakhale nthawi yomwe mankhwalawa amamwa mankhwalawa masana, kapena makonzedwe omwewo munthawi yomweyo samakhudza mayamwidwe a rabeprazole.

Kutenga mankhwalawa ndi zakudya zamafuta kumachepetsa kuyamwa kwa rabeprazole kwa maola 4 kapena kupitilira apo, komabe, Cmax kapena kuchuluka kwa mayamwidwe sikusintha.

Kumangidwa kwa rabeprazole ku mapuloteni a plasma kuli pafupifupi 97%.

Kutetemera ndi chimbudzi

Metabolite yayikulu ndi thioether (M1). Metabolite yokhayo yomwe imagwira ntchito ndi desmethyl (M3), komabe, idatsimikizika mu ndende zochepa m'mgulu limodzi lomwe limatenga nawo kafukufuku wa rabeprazole pa 80 mg.

Mlingo umodzi wa 14C wolembedwa kuti rabeprazole sodium pa 20 mg, mankhwala osasinthika sanapezeke mkodzo.

Pafupifupi 90% ya rabeprazole imachotseredwa kudzera mu impso makamaka mwa ma metabolites awiri: conjugate ya mercapturic acid (M5) ndi carboxylic acid (M6), komanso mawonekedwe a metabolites awiri osadziwika omwe adadziwika pakuwunikira kwa sumu. Sodium yotsalira ya rabeprazole yotengedwa imatuluka m'matumbo.

Kuchotsa kwathunthu ndi 99.8%. Izi zimawonetsa kachulukidwe kakang'ono ka rabeprazole sodium metabolites ndi bile.

M'magulu odzipereka athanzi, plasma T1 / 2 ili pafupifupi ola limodzi (kuyambira 0,7 mpaka 1.5 maola), ndipo chilolezo chonse ndi 3.8 ml / min / kg.

Pharmacokinetics pamagulu apadera a odwala

Odwala omwe ali ndi chiwindi chambiri, AUC imachulukitsidwa kawiri poyerekeza ndi odzipereka athanzi, zomwe zimawonetsa kuchepa kwa metabolism panthawi ya "pass yoyamba", ndipo T1 / 2 kuchokera ku plasma yamagazi imachulukitsidwa katatu.

Odwala okhazikika kumapeto kwa gawo aimpso kulephera amene amafuna kukonza hemodialysis (CC

• Makapu amodzi a Bilobil ali ndi 40 mg kuchokera ku masamba a mtengo ginkgo-masamba awiri.
• Kapu imodzi imodzi ya Bilobil Forte imaphatikizapo 80 mg kuchokera kwa masamba a mtengo ginkgo-masamba awiri.

100 mg ya Tingafinye timaphatikizapo 19.2 mg ginkgo glycosides mtundu wa flavone ndi 4.

8 mg miyala ya terpene lembani (bilobalides ndi ginkgolides).

Zowonjezera: colloidal silicon oxide, wowuma chimanga, lactose monohydrate, magnesium stearate, talc.

Mapangidwe a Shell: utoto wofiira wachitsulo, titanium dioxide, azorubine, utoto wakuda zitsulo, gelatin.

Kutulutsa Fomu

Makapisozi a pinkatinatin, mkati mwake muli ufa wa bulauni wokhala ndi tinthu tating'ono tosiyanasiyana. Makapisozi 10 mumchimake, matuza awiri kapena asanu ndi mmodzi mumakatoni.

Zotsatira za pharmacological

Neurometabolic, antihypoxiczomwe zimakongoletsa kuyera kwazinthu zam'mimba, zimathandizira kufalikira kwamtunda ndi chithokomiro, angioprotective, antioxidant machitidwe.

Pharmacodynamics ndi pharmacokinetics

Mankhwala

Phytopreparation, normalizing kagayidwe m'maselo rheological Zizindikiro magazi ndi minofu mafuta.

Zimasintha kufalikira kwa ziwalo za m'magazi ndipo zimapatsa ubongo shuga ndi mpweyaamalepheretsa kuphatikizika maselo ofiira amwaziimachepetsa kutsegulira kuchuluka kwa mapulateleti.

Amakhala ndi amadalira mlingo wa mtima pa mtima, amathandizira kupanga AYI, imakulitsa kuunikira kwa ma arterioles, kumawonjezera mamvekedwe a mitsempha, potero kusintha kusintha kwa mitsempha yamagazi. Imafooketsa kutsika kwa khoma la chotengera.

Zinthu antithrombotic zochita (kumalimbitsa zimimba za maselo ofiira am'magazi ndi mapulateleti, zimakhudza biosynthesis ma prostaglandinsImafooketsa zotsatira kuphatikiza mapulateleti) Zimalepheretsa peroxidation wamafuta a zimagwira ma cell ndikumapangidwa kwa ma free radicals.

Matenda a metabolism ma neurotransmitters (monga dopamine, norepinephrine ndi acetylcholine) Ndiponso antihypoxic kuchitapo, kumapangitsa kagayidwe, kumalimbikitsa kudziunjikira macroergsimathandizira kutaya shuga ndi mpweyaamawongolera njira zoyimira pakati mu ubongo.

Pharmacokinetics

Pambuyo kutenga bioavailability bilobalida ndi ginkgolides ndi 85%. Kuzindikira kwakukulu kumachitika patatha maola awiri mutamwa mankhwalawa. Kutha kwa theka-moyo ndi maola 4-10. Ma mamolekyulu azinthu izi samasokonekera mthupi ndipo amatulutsidwa kwathunthu ndi mkodzo, pang'ono - - ndi ndowe.

Zizindikiro zogwiritsidwa ntchito

• Kuchepa kwamphamvu kwa magazi ndi kufalikira kwa padera, Matenda a Raynaud.

Discirculatory encephalopathy chifukwa cha sitiroko, zowawa, zaka komanso zifukwa zina, zomwe zimatsatana ndi kufooka kwa kukumbukira, chidwi, kuchepa kwa kuzindikira, kusintha kwa magonedwe.

Contraindication

• Erosive gastritis.
• Kuchepetsa coagulability.
• Ngozi yamitsempha yamagazi.
• Zilonda zam'mimba mu gawo la pachimake.
• Myocardial infaration.
• Kuzindikira ku zigawo za mankhwala.
• Zaka mpaka 18.

Zotsatira zoyipa

• Zotsatira za ntchito yamanjenje: kusowa tulo, mutukusamva makutu, chizungulire.

Makapiritsi (mapiritsi) Bilobil, malangizo ogwiritsira ntchito

At discirculatory encephalopathy gwiritsani ntchito makapisozi atatu katatu patsiku.

Mankhwalawa kuphwanya malamulokuyesa ndi kufalikira kwazungulira, Matenda a Raynaud kutenga kapisozi 1 katatu patsiku.

At diabetesic retinopathy, sensorineural matendazaka dkusintha kwachulukidwe vomerezani kapisozi katatu patsiku.

Bongo

Ngati kuchuluka kwake kuchulukitsidwa, zomwe zimachitika mutakumana ndi zovuta zimatha. Mankhwalawa ndi achikhalidwe, kutengera zisonyezo.

Malangizo apadera

The achire zotsatira za mankhwalawa zimachitika pafupifupi mwezi umodzi kumwa mankhwalawo. Ngati munthawi ya mankhwalawa pakakhala kuwonongeka modzidzimutsa, kusowa kwa makutu, tinnitus kapena chizungulire kuwoneka, muyenera kusiya kumwa mankhwalawo ndikulakalaka upangireni dokotala.

Sitikulimbikitsidwa kusankha Bilobil kwa odwala omwe ali ndi galactose kapena glucose malabsorption syndrome, kobadwa nako galactosemia kapena kuperewera kwa lactase, chifukwa lactose ndi gawo limodzi la iwo.

Kuyanjana kwa mankhwala osokoneza bongo

Bilobil sayenera kutumizidwa kwa odwala omwe amakonda kumwa mankhwala omwe amachepetsa magazi (mwachitsanzo, acetylsalicylic acid ndi mankhwala ena osapweteka a antiidal, othana ndi anticoagulants). Kuphatikiza koteroko kumatha kuchulukitsa chiopsezo chakutuluka kwa magazi chifukwa cha kuchuluka kwa nthawi yowundana.

Tidalemba ndemanga za anthu za mankhwala a Bilobil:

1. Chiyembekezo Pambuyo pakumalizidwa kwa ubongo ndi mitsempha yamagazi muubongo, Bilobil Forte adatumiza adotolo, amamwa pafupifupi chaka chathunthu ndipo samatha kumvetsetsa chifukwa chake kupanikizika kudakhala kotsika ndi 10070, ndipo kudachitika ngakhale kutsika, ndipo kugunda kwake kudumphira mpaka 120, adamva kuwawa kwambiri, kusiya kumwa ndipo pang'onopang'ono zonse zidayamba kuti mukhale bwino, kuti wina achiritsidwe ndi wina wolumala, muyenera kusamala kwambiri ndi mankhwalawa. Zaumoyo kwa onse.
2. Galina. Anamwa mwezi mwakhama, adachotsedwa ku khomo lachiberekero la cervical osteochondrosis. Mutuwu ndi mawonekedwe amaso, khungu. Sizinathandize konse.
3. Olga Ndidatenga makapisozi pambuyo povulala pamayendedwe a dokotala kuti andichotsere zotsalazo. "Bilobil" adathandizira kuchotsa tinnitus ndikuwongolera kukumbukira.
4. Zina. Kutsika mtengo sikutanthauza kukhala wabwinoko! Bilobil Intens 120mg: paketi ya makapisozi 60 imakhala ndi ma ruble 970, mtengo wa tanakan 40mg pama mapiritsi 90 a 1580, pamene tanakan sanandithandizire, ndipo Bilobil intens inakwera. Mavuto amakumbukiro amafuna yankho mu mankhwala apamwamba, odalirika. Kulimba mtima kwa Bilobil kunandichitira ndipo sindilinso ndi vuto la kukumbukira. Ndipo mutu suzungulira, sukupweteka. Koma chachikulu ndichakuti, ndikakhala ndi mutu womveka bwino ndizosavuta kugwira ntchito ndikuchita zinthu za tsiku ndi tsiku.
5. Olya. Ndinkamwa maphunziro a miyezi iwiri a bilobil. Kumva bwino. Mutu wanga unawala, ndikosavuta kuganiza, ndimakumbukira chilichonse ndipo sindisokoneza chilichonse. Zosakondweretsa monga chizungulire zapita, ndipo luso la kuzindikira lachuluka monga ubwana. Bilobil ndiwabwino kuposa mankhwala ambiri okhala ndi ginkgo, awa ndi mankhwala, osati oyipa, achilengedwe komanso amphamvu, chifukwa chake ndikumva bwino. Asanamwe kumwa ginkoom, koma sizinachitike. Pambuyo pa ginkoom, ndimadutsa zoyipa zonse. Ndipo Bilobil ndi mankhwala osokoneza bongo. Yofunika ndalamazo.

Madokotala ambiri amapereka umboni kuti kutulutsa mitengo ya ginkgo pafupifupi ndi mankhwala okhawo omwe amawongolera chidziwitso cha odwala okalamba. Komabe, kafukufuku adawonetsanso kuti atachotsa Bilobil mwa odwala am'gulu lino, kuyambiranso kwa zomwe zimayenderana ndi zaka.

Zofananira za mankhwalawa ndi mankhwala Bilobil, Vitrum Memori, Gingium, Ginos, Memoplant ndi Tanakan.

Bilobil analogues ndi mankhwala monga:

• Memantine
• Memorel,
• Noojeron
• Akatinol Memantine,
• Alzeym
• Intellan
• Memaneirin
• Memor
• Maruks
• Memantinol
• Memikar.

Musanagwiritse ntchito fanizo, funsani dokotala.

Zosungirako ndi moyo wa alumali

Mankhwalawa ndi oyenera kugwiritsidwa ntchito zaka zitatu. Musapatse ana mwayi, muteteze ku kuwala. Kutentha kosungirako 200C.

Zachipatala ndi gulu la mankhwala

Inhibitor ya H + -K + -ATPase. Mankhwala a antiulcer

Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD

◊ Makapisozi obwera gelatin yolimba, kukula No. 3, yokhala ndi thupi loyera komanso chophimba cha buluu, zomwe zili m'mabotolowa ndizovala zazifupi kuyambira zoyera mpaka zoyera ndi zonona zonona kapena zachikasu.

* rabeprazole, pellet thunthu 8,5% - 118 mg.

Omwe amathandizira: magawo a shuga (sucrose - 99.83%, povidone - 0,17%) - 71.46 mg, sodium carbonate - 1.66 mg, talc - 1.77 mg, titanium dioxide - 0,83 mg, hypromellose - 14,75 mg.

Omwe amachokera ku chipolopolo: hypromellose phthalate - 15,94 mg, mowa wa cetyl - 1.59 mg.
The zikuchokera kapisozi zolimba gelatin No. 3: kapisozi thupi - titanium dioksidi - 2%, gelatin - mpaka 100%, kapisozi - titanium dioxide - 2%, utoto utoto utoto - 0,0176%, utoto wakuda wa diamondi - 0,0051%, gelatin - mpaka 100%.

Ma PC 5. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni. 7 ma PC. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni 10 ma PC. - mapaketi a matuza (1, 2, 3) - mapaketi a makatoni.

14 ma PC. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni. ma 15 ma PC. - matumba otupa (1, 2, 3) - mapaketi okhala ndi makatoni 20 ma PC. - mapaketi a matuza (1, 2, 3) - mapaketi a makatoni.

30 ma PC - mapaketi a matuza (1, 2, 3) - mapaketi a makatoni.

Zotsatira za pharmacological

Inhibitor ya H + -K + -ATPase. Mankhwala a antiulcer.

Sodium ya Rabeprazole ndi ya gulu la mankhwala antisecretory ochokera ku benzimidazole. Sodium ya Rabeprazole imalepheretsa kubisika kwa madzi am'mimba mwachangu poletsa H + / K + -ATPase pazinsinsi za maselo a parietal m'mimba.

H + / K + -ATPase ndi mapuloteni ovuta omwe amagwira ntchito ngati pampu ya proton, motero rabeprazole sodium ndi cholepheretsa pampu ya proton m'mimba ndikutseka gawo lomaliza la asidi.

Izi zimadalira mlingo ndipo zimatsogolera kukaponderezedwa kwa zonse zoyambira komanso kusungidwa kwa secretion wa asidi, mosasamala kanthu za zotsitsimutsa. Sodium ya Rabeprazole ilibe katundu wa anticholinergic.

Pambuyo pakukonzekera kwa rabeprazole sodium pa 20 mg, antisecretory effect imayamba mkati mwa ola limodzi. Kulepheretsa kwa basal ndikulimbikitsidwa asidi katulutsidwe patatha maola 23 mutatenga mlingo woyamba wa sodium ya rabeprazole ndi 69% ndi 82%, motero, ndipo kumatenga mpaka maola 48.

Kutalika kwa nthawi ya pharmacodynamic zochita kumapitilira zomwe zinanenedweratu ndi T1 / 2 (pafupifupi ola limodzi). Izi zitha kufotokozedwa ndi kumangidwa kwa mankhwala kwa nthawi yayitali kwa H + / K + -ATPase ya maselo a parietal m'mimba.

Ubwino wa inhibitory mphamvu ya rabeprazole sodium pa asidi secretion umafika pagome patatha masiku atatu atamwa rabeprazole sodium. Mukasiya kutenga ntchito zachinsinsi imabwezeretsedwa mkati mwa masiku 1-2.

Zokhudza kuchuluka kwa gastrin m'magazi

M'mayesero azachipatala, odwala adatenga rabeprazole sodium mu Mlingo wa 10 kapena 20 mg tsiku lililonse kwa nthawi yayitali ya miyezi 43. The kuchuluka kwa gastrin mu madzi am`magazi anachulukitsidwa kwa masabata 2-8 oyamba, zomwe zimawonetsa kulepheretsa kwapadera kwa asidi. The kuchuluka kwa gastrin kubwerera kwawo koyambirira nthawi zambiri mkati mwa masabata 1-2 atasiya kulandira chithandizo.

Zotsatira zamaselo ofanana ndi a enterochromaffin

Mukamayang'ana zitsanzo zam'mimba za munthu kuchokera pansi pa mmimba ndi pansi pamimba, odwala 500 omwe adalandira rabeprazole sodium kapena mankhwala osiyanitsa kwa masabata 8, kusintha kosasintha kwa maselo a cell of enterochromin, kukula kwa gastritis, kuchuluka kwa atrophic gastritis, metaplasia wamatumbo kapena kufalikira kwa Helicobacter. wapeza.

Pakufufuza kwa odwala oposa 400 omwe adalandira rabeprazole sodium (10 mg / tsiku kapena 20 mg / tsiku) kwa chaka chimodzi, zochitika za hyperplasia zinali zochepa komanso zofanana ndi zomwe zimachitika mu omeprazole (20 mg / kg). Panalibe milandu yovuta kusintha kapena zotupa zama carcinoid zomwe zimadziwika m'makola.

Zotsatira zamachitidwe a rabeprazole sodium mogwirizana ndi dongosolo lamkati lamanjenje, mtima kapena kupuma pakadali pano sizinapezeke.

Zinawonetsedwa kuti sodium ya rabeprazole, ikamamwa pakamwa 20 mg kwa masabata awiri, sizikhudza ntchito ya chithokomiro, kuchuluka kwa kagayidwe kamwazi m'magazi, komanso kuchuluka kwa cortisol, estrogen, testosterone, prolactin, glucagon, FSH, LH , renin, aldosterone ndi mahomoni okula.

Pharmacokinetics

Zogulitsa ndi kugawa

Rabeprazole imatengedwa mwachangu kuchokera m'matumbo, Cmax m'magazi am'magazi amafikira pafupifupi maola 3.5 atatha kutumikiridwa pa mlingo wa 20 mg. Kusintha kwa Cmax mu plasma yamagazi, mfundo za AUC za rabeprazole ndizofanana pamlingo wambiri kuchokera 10 mpaka 40 mg.

Mtheradi bioavailability pambuyo m`kamwa makonzedwe pa 20 mg (poyerekeza iv) pafupifupi 52%. Kuphatikiza apo, bioavailability sasintha ndi Mlingo wambiri wa rabeprazole. Ngakhale nthawi yomwe mankhwalawa amamwa mankhwalawa masana, kapena makonzedwe omwewo munthawi yomweyo samakhudza mayamwidwe a rabeprazole.

Kutenga mankhwalawa ndi zakudya zamafuta kumachepetsa kuyamwa kwa rabeprazole kwa maola 4 kapena kupitilira apo, komabe, Cmax kapena kuchuluka kwa mayamwidwe sikusintha.

Kumangidwa kwa rabeprazole ku mapuloteni a plasma kuli pafupifupi 97%.

Kutetemera ndi chimbudzi

Metabolite yayikulu ndi thioether (M1). Metabolite yokhayo yomwe imagwira ntchito ndi desmethyl (M3), komabe, idatsimikizika mu ndende zochepa m'mgulu limodzi lomwe limatenga nawo kafukufuku wa rabeprazole pa 80 mg.

Mlingo umodzi wa 14C wolembedwa kuti rabeprazole sodium pa 20 mg, mankhwala osasinthika sanapezeke mkodzo.

Pafupifupi 90% ya rabeprazole imachotseredwa kudzera mu impso makamaka mwa ma metabolites awiri: conjugate ya mercapturic acid (M5) ndi carboxylic acid (M6), komanso mawonekedwe a metabolites awiri osadziwika omwe adadziwika pakuwunikira kwa sumu. Sodium yotsalira ya rabeprazole yotengedwa imatuluka m'matumbo.

Kuchotsa kwathunthu ndi 99.8%. Izi zimawonetsa kachulukidwe kakang'ono ka rabeprazole sodium metabolites ndi bile.

M'magulu odzipereka athanzi, plasma T1 / 2 ili pafupifupi ola limodzi (kuyambira 0,7 mpaka 1.5 maola), ndipo chilolezo chonse ndi 3.8 ml / min / kg.

Pharmacokinetics pamagulu apadera a odwala

Odwala omwe ali ndi chiwindi chambiri, AUC imachulukitsidwa kawiri poyerekeza ndi odzipereka athanzi, zomwe zimawonetsa kuchepa kwa metabolism panthawi ya "pass yoyamba", ndipo T1 / 2 kuchokera ku plasma yamagazi imachulukitsidwa katatu.

Odwala okhazikika kumapeto kwa gawo aimpso kulephera amene amafuna kukonza hemodialysis (CC

• Makapu amodzi a Bilobil ali ndi 40 mg kuchokera ku masamba a mtengo ginkgo-masamba awiri.
• Kapu imodzi imodzi ya Bilobil Forte imaphatikizapo 80 mg kuchokera kwa masamba a mtengo ginkgo-masamba awiri.

100 mg ya Tingafinye timaphatikizapo 19.2 mg ginkgo glycosides mtundu wa flavone ndi 4.

8 mg miyala ya terpene lembani (bilobalides ndi ginkgolides).

Zowonjezera: colloidal silicon oxide, wowuma chimanga, lactose monohydrate, magnesium stearate, talc.

Mapangidwe a Shell: utoto wofiira wachitsulo, titanium dioxide, azorubine, utoto wakuda zitsulo, gelatin.

Kutulutsa Fomu

Makapisozi a pinkatinatin, mkati mwake muli ufa wa bulauni wokhala ndi tinthu tating'ono tosiyanasiyana. Makapisozi 10 mumchimake, matuza awiri kapena asanu ndi mmodzi mumakatoni.

Zotsatira za pharmacological

Neurometabolic, antihypoxiczomwe zimakongoletsa kuyera kwazinthu zam'mimba, zimathandizira kufalikira kwamtunda ndi chithokomiro, angioprotective, antioxidant machitidwe.

Pharmacodynamics ndi pharmacokinetics

Mankhwala

Phytopreparation, normalizing kagayidwe m'maselo rheological Zizindikiro magazi ndi minofu mafuta.

Zimasintha kufalikira kwa ziwalo za m'magazi ndipo zimapatsa ubongo shuga ndi mpweyaamalepheretsa kuphatikizika maselo ofiira amwaziimachepetsa kutsegulira kuchuluka kwa mapulateleti.

Amakhala ndi amadalira mlingo wa mtima pa mtima, amathandizira kupanga AYI, imakulitsa kuunikira kwa ma arterioles, kumawonjezera mamvekedwe a mitsempha, potero kusintha kusintha kwa mitsempha yamagazi. Imafooketsa kutsika kwa khoma la chotengera.

Zinthu antithrombotic zochita (kumalimbitsa zimimba za maselo ofiira am'magazi ndi mapulateleti, zimakhudza biosynthesis ma prostaglandinsImafooketsa zotsatira kuphatikiza mapulateleti) Zimalepheretsa peroxidation wamafuta a zimagwira ma cell ndikumapangidwa kwa ma free radicals.

Matenda a metabolism ma neurotransmitters (monga dopamine, norepinephrine ndi acetylcholine) Ndiponso antihypoxic kuchitapo, kumapangitsa kagayidwe, kumalimbikitsa kudziunjikira macroergsimathandizira kutaya shuga ndi mpweyaamawongolera njira zoyimira pakati mu ubongo.

Pharmacokinetics

Pambuyo kutenga bioavailability bilobalida ndi ginkgolides ndi 85%. Kuzindikira kwakukulu kumachitika patatha maola awiri mutamwa mankhwalawa. Kutha kwa theka-moyo ndi maola 4-10. Ma mamolekyulu azinthu izi samasokonekera mthupi ndipo amatulutsidwa kwathunthu ndi mkodzo, pang'ono - - ndi ndowe.

Zizindikiro zogwiritsidwa ntchito

• Kuchepa kwamphamvu kwa magazi ndi kufalikira kwa padera, Matenda a Raynaud.

Discirculatory encephalopathy chifukwa cha sitiroko, zowawa, zaka komanso zifukwa zina, zomwe zimatsatana ndi kufooka kwa kukumbukira, chidwi, kuchepa kwa kuzindikira, kusintha kwa magonedwe.

Contraindication

• Erosive gastritis.
• Kuchepetsa coagulability.
• Ngozi yamitsempha yamagazi.
• Zilonda zam'mimba mu gawo la pachimake.
• Myocardial infaration.
• Kuzindikira ku zigawo za mankhwala.
• Zaka mpaka 18.

Zotsatira zoyipa

• Zotsatira za ntchito yamanjenje: kusowa tulo, mutukusamva makutu, chizungulire.

Malangizo ogwiritsira ntchito (Njira ndi Mlingo)

Makapisozi ayenera kumezedwa ndi madzi. Musanayambe kumwa ndikulimbikitsidwa kukaonana ndi dokotala. Zizindikiro zakusintha zitha kuwoneka pambuyo pa mwezi umodzi wa chithandizo. Kutalika kwa chithandizo sikuyenera kupitilira miyezi itatu.

Makapiritsi (mapiritsi) Bilobil, malangizo ogwiritsira ntchito

At discirculatory encephalopathy gwiritsani ntchito makapisozi atatu katatu patsiku.

Mankhwalawa kuphwanya malamulokuyesa ndi kufalikira kwazungulira, Matenda a Raynaud kutenga kapisozi 1 katatu patsiku.

At diabetesic retinopathy, sensorineural matendazaka dkusintha kwachulukidwe vomerezani kapisozi katatu patsiku.

Malangizo ogwiritsira ntchito Bilobil Forte ndi Bilobil Intens 120

Bilobil Forte nthawi zambiri amatengedwa kapisozi kamodzi kapena katatu pa tsiku, ndipo Bilobil Intens 120 amatengedwa 1 kapisozi 1 nthawi imodzi (m'mawa) kapena 2 nthawi (m'mawa ndi madzulo) patsiku.

Bongo

Palibe malipoti a milandu yokhudza bongo.

Ndemanga za Bilobil

Ndemanga za Bilobil Fort, Bilobil ndi Bilobil Intens ndizofanana ndipo ngati zikugwiritsidwa ntchito moyenera, zikuwonetsa kufalikira kwa mankhwalawa pokonzanso magazi.

Ndemanga za madotolo zimatengera umboni wosasinthika, womwe ukunena kuti kuchotsa kwa mitengo ya Ginkgo pafupifupi chida chokhacho chomwe chimapangitsa kuti odwala achikulire azigwira bwino ntchito.

Komabe, kafukufuku adawonetsanso kuti zizindikiro zokhudzana ndi zaka zimakonda kubwerera pambuyo pochotsa mankhwala.

Mtengo, kuti mugule

Ku Russia, mtengo wa Bilobil No. 20 ndi ma ruble 156-211, mtengo wa Bilobil Forte No. 20 ndi ma ruble 273-290, ndipo mtengo wa Bilobil Intens No. 20 uyambira pa ruble 418.

Ku Ukraine, mitengo ya mankhwalawa ndi 99, 152 ndi 203 hhucnias, motero.

• Mankhwala ogulitsa pa intaneti ku Russia
• Mankhwala ogulitsa pa intaneti ku UkraineUkraine
• Mankhwala ogulitsa pa intaneti ku Kazakhstan

• Bilobil makapisozi 40 mg 60 ma PC KRKA KRKA
• Bilobil forte makapisozi 80 mg 60 ma PC KRKA KRKA
• Bilobil Intens 120 makapisozi 120 mg 60 ma PC KRKA KRKA
• Bilobil Intens 120 makapisozi 120 mg 20 ma PC KRKA KRKA
• Bilobil forte makapisozi 80 mg 20 ma PC KRKA KRKA

• Bilobil 40mg No. 20 makapisozi KRKA-Rus
• Bilobil Forte 80mg No. 60 makapisozi KRKA-Rus
• Bilobil 40mg No. 60 makapisozi KRKA-Rus
• Bilobil Forte 80mg No. 20 makapisozi KRKA-Rus
• Bilobil Intense 120mg No. 60 makapisozi KRKA-Rus

Mankhwala IFK

• Bilobil Forte KRKA, Slovenia
• Bilobil Intens 120KRKA, Slovenia
• Bilobil Intens 120KRKA, Slovenia
• Bilobil Forte KRKA, Slovenia

• Bilobil forte makapisozi 80mg No. 20KPKA (Slovenia)
• Bilobil makapisozi 40mg No. 60KPKA (Slovenia)
• Bilobil forte makapisozi 80mg No. 60KKKA (Slovenia)

Pani Pharmacy

• Zisoti za Bilobil. 40mg No. 20KKKA
• Zisoti za Bilobil. 40mg No. 20KKKA
• Zisoti za Bilobil. 40mg No. 20KKKA
• Zisoti za Bilobil. 40mg No. 20KKKA

• Bilobil Intens 120 mg No. 60 zisoti.
• Bilobil forte 80 mg No. 20 zisoti.
• Bilobil forte 80 mg No. 60 zisoti.

LAPANI ZOTSATIRA! Zambiri pamankhwala omwe ali pamalowo ndizokhudza zonse, zomwe zimatengedwa kuchokera kwa anthu ndipo sizingagwiritsidwe ntchito ngati lingaliro la kugwiritsa ntchito mankhwala munthawi ya chithandizo. Musanagwiritse ntchito mankhwala Bilobil, onetsetsani kuti mwawonana ndi dokotala.