Zomwe ma statins ndizabwino kwa cholesterol

Chiwerengero cha anthu omwe akudwala cholesterol yayikulu imachuluka chaka chilichonse. Nthawi zambiri izi zimabweretsa kukula kwa matenda osiyanasiyana a mtima, ndipo pamapeto pake kufa msanga. Kumwa mankhwala ochepetsa mphamvu ya cholesterol kumathandizira kupewa izi. Ndikofunika kukumbukira kuti ndi dokotala yekha, wodziwa cholesterol okwera m'magazi, omwe angafotokozere chithandizo chofunikira kwa aliyense payekha. Kuganiza kuti mankhwala omwe amachepetsa cholesterol ali ndi mavuto, kudzisankhira nokha mankhwala omwe amadzidziwitsa ena popanda kufunsa katswiri kungakhale koopsa.

Mankhwala ochepetsa cholesterol

Kukonzekera kutsitsa cholesterol kumagawidwa m'mitundu yosiyanasiyana:

1. Madera
2. Fibates
3. Niacin
4. Zoletsa
5. Mafuta Polyunsaturated Acids
6. Sequestrants ya bile acid.

Mtundu uliwonse wamankhwala uli ndi zabwino zake, zovuta zake komanso mawonekedwe osiyanasiyana ogwiritsira ntchito. Munjira zambiri, kusankha kwa dokotala kumadalira thanzi la anthu komanso kupezeka kwa matenda ena wodwala.

Magulu a Statin

Ma cholesterol am'badwo woyamba ndi pravastatin, lovastatin ndi fluvastatin. Komabe, pakadali pano mankhwalawa amalembedwa kawirikawiri. "Kuchotsa" kwawo kwakukulu ndikutulutsa kwakuthupi kuchokera m'thupi. Popeza kuti cholesterol synthesis imagwira kwambiri usiku, muyenera kudya ma statins musanayambe kugona. Simvastatin, mankhwala wachiwiri, ali ndi vuto lomweli, koma amalamulidwa nthawi zambiri.

Mu 2015, ma statins odziwika kwambiri a m'badwo watsopano ndi atorvastatin ndi rosuvastatin. Amakhala nthawi yayitali mthupi, motero nthawi yakumwa kwawo sikuti kwenikweni.

Mankhwalawa amagwira ntchito motere: ma statins amateteza enzyme ya chiwindi, yomwe imalimbikitsa kupanga mafuta m'thupi. Kwa munthu yemwe ali ndi chiwindi chathanzi, mankhwalawa si owopsa, komabe, pakakhala matenda ena akuluakulu a chiwalo ichi, ma statins sanadziwike.

Ma statin onse amayenera kumwedwa kamodzi patsiku, koma mankhwala aliwonse amathandizanso kuchepetsa mafuta m'thupi. Mwachitsanzo, mapiritsi a simvastatin mu mlingo wa 40 mg, atorvastatin - 20 mg ndi rosuvastatin - 10 mg ali ndi zofanana. Mlingo wapamwamba tsiku lililonse wa mankhwalawa ndi 160 mg, 80 mg ndi 40 mg, motero.

Zabwino ndi zoyipa zama statins

Mwa zabwino zomwe mankhwalawa ali nacho, kuwonjezera pa kuchepa kwenikweni kwa mafuta m'thupi, zotsatirazi ziyenera kudziwika:

• Zomwe zimachitika pakalandiridwe zimadziwika pambuyo pa masabata awiri,
• Ma boma ndi otetezeka kwathunthu ngati mukugwiritsa ntchito nthawi yayitali,
• Chiwopsezo chachikulu cha matenda a mtima.

Zina mwa zolephera ndizowonjezereka kwa matenda a chiwindi, kufunika kowunikira "kuyesedwa kwa chiwindi", kuwonetsa kwa zovuta zina (nseru, kupweteka kwapakhosi pamimba kapena minofu).

Mankhwala obwera mwatsopano

Mapiritsi onse a gulu la statin, ali ndi zinthu zomwezo ndi contraindication, ofanana ndi kapangidwe kake ndi kagwiritsidwe ntchito kake.

Kusiyana pakati pa oimira a m'badwo watsopano wa atorvastatin ndi rosuvastatin ali m'gulu lomwe limapangidwa pazomwe zimapangidwa, komanso muyezo: kukwaniritsa zotsatira zomwezo, rosuvastatin amafunika nthawi 2 zosakwana atorvastatin. Talingalirani za izi za ma statin pazitsanzo za woimirira kwambiri m'gulu lino - ma Atoris statins.

Mapiritsi a cholesterol omwe ali ndi dzina lamalonda "Atoris" ali ndi chophatikizika - atorvastatin ndi opezekapo, makamaka lactose monohydrate. Pali mitundu itatu ya mankhwalawa: Atoris 10 (piritsi 1 lili ndi 10 mg ya atorvastatin), Atoris 20 (20 mg ya atorvastatin) ndi Atoris 40 (piritsi lililonse lili ndi 40 mg yogwira ntchito).

Atoris ali ndi zotsutsana zingapo pakugwiritsa ntchito. Monga mankhwala ena aliwonse omwe amapezeka mu gulu la statin, Atoris imabweretsa chiwindi - osavomerezeka kuti atenge chiwindi chachikulu cha hepatitis, kulephera kwa chiwindi, matenda enaake, chiwopsezo cha zochitika za hepatic transaminases, matenda a minofu, amayi oyembekezera komanso oyembekezera wazaka. Kuphatikiza apo, "Atoris" iyenera kumwedwa mosamala kwa anthu omwe ali ndi matenda monga uchidakwa, owonjezera ubongo, sepsis, ndi khunyu.

Mapiritsi okhala ndi cholesterol yambiri

Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.

Kholesterol yokwezeka yomwe imakweza kwambiri chiwopsezo cha kugunda kwa mtima ndi stroko. Cholesterol, yoyenda m'mphepete mwa magazi, imatha kukhazikika pamakoma a mitsempha yamagazi, ikuchepetsa lumen, ndikupanga cholesterol plaques. Ngati pali zovuta zina - kukalamba, aneurysm, mtima kapena stroko - kuchepa kwa zotengera kumayambitsa kuvulaza kwamtundu, pomwe chiopsezo chotenga matenda ena a mtima chikukula.

• Mankhwala a Statin
• Onjezerani Mankhwala Osokoneza bongo
• Mankhwala ena otsitsa cholesterol
• Ubwino ndi zotsatira zoyipa za mankhwala opatsirana ndi lipid

Kuti muchepetse cholesterol yamagazi, pali mankhwala apadera.

Mapiritsi a cholesterol ayenera kuthandizidwa ndi adokotala, motsogozedwa ndi zofunikira zake, popeza kudya kosalamulirika kumabweretsa zotsatirapo zoyipa.

Wodwala amene akayezetsa magazi ndi cholesterol yokwera kuti sanalandire chithandizo chamankhwala, ayenera kuonanso zakudya ndi moyo wake, osamwa yekha mankhwalawo kuti asadzivulaze.

Pali magulu angapo a mankhwala ochepetsa magazi m'thupi:

• ma statins
• mafupa
• zinthu zomwe zimawonjezera katulutsidwe a ma asidi a bile,
• niacin ndi niacin zotumphukira,
• othandiza lipid-kuchepetsa mankhwala.

Amasiyana mu kapangidwe kake (chachikulu yogwira pophika) ndi njira yochepetsera ndende ya cholesterol.

Mankhwala a Statin

Ma statin onse amatha kugawidwa m'magulu angapo malinga ndi zomwe zikuchitika pakapangidwe kake.

Mndandanda wazotheka

• simvastatin
• fluvastatin
• atorvastatin,
• rosuvastatin.

Kukonzekera ndi yogwira mankhwala simvastatin (mayina ogulitsa Vazilip, Zokor, Simvakard) ndi amodzi mwa mzere woyamba wa mzere wa mankhwala omwe ali pompopompo kuti muchepetse mafuta m'thupi.

Makina a zochita za simvastatin amaphunziridwa bwino komanso angadziwike, koma pakadali pano, ndalama zomwe zili ndi zomwe sizigwiritsidwa ntchito machitidwe azachipatala chifukwa cha mawonekedwe a mankhwala ogwira mtima. Mlingo wambiri, kugwiritsa ntchito simvastatin ndikosayenera, chifukwa kumabweretsa chitukuko, mavuto omwe amadza chifukwa chamadotowa nthawi zambiri amaposa phindu.

Mtengo woyeserera wa mankhwala okhala ndi simvastatin ku Russia amachokera ku ruble 100 mpaka 600, kutengera dziko lomwe adachokera.

Ziyeso zamankhwala za atorvastatin ndizothandiza kawiri kuposa simvastatin.

Kugwiritsa ntchito kwambiri kwa gululi kwamankhwala kumakupatsani mwayi wogwiritsa ntchito zinthu zochepa zomwe zimapangitsa kuti mupewe chiopsezo chaumoyo pazotsatira zoyipa. Mankhwala a Atorvastatin amatha kutsitsa cholesterol mwachangu kwambiri. Mtengo wa mankhwala m'gululi umachokera ku ruble 200 mpaka 800, kutengera kampani yopanga mankhwala.

Izi zikuphatikiza:

• Atomax
• Tulip
• Liprimar.

Rosuvastatin ndiye chinthu chatsopano kwambiri pakadali pano, kukulolani kuti muchepetse cholesterol yamagazi. Pankhani ya potency, imaposa mankhwala onse omwe ali pamwambapa ndipo kale Mlingo wochepetsetsa kwambiri umakhala ndi vuto loonekera pa cholesterol yayikulu. Amagwiritsidwa ntchito pazochitika zochulukirapo za cholesterol yeniyeni. Ku Russia, mtengo wamankhwala omwe ali ndi rosuvastatin amachokera ku 300 mpaka 1000 rubles. Kukonzekera ndi ntchito yogwira ntchito kumaphatikizapo:

Perekerani Mankhwala Osokoneza bongo

Ziphuphu ndi mankhwala omwe mankhwala omwe amapezeka ndi mphamvu ya folic acid. Zinthu izi zimamangiriza bile bile, potero zinalepheretsa kugwira ntchito kwa chiwindi komanso kutsitsa kupanga mafuta m'thupi. Mwanjira iyi, momwe amagwirira ntchito awo ndi ofanana ndi ma statins, koma ali ndi chinthu china pakuphatikizika.

Mitundu yamitundu ina:

• fenofibrate
• kaprofibrate
• gemfibrozil
• onjezerani.

Mankhwala omwe amagwiritsidwa ntchito kwambiri pazachipatala ndi gemfibrozil ndi fenofibrate.

Gemfibrozil ndi wowopsa ndipo nthawi yomweyo amagwira bwino kwambiri polimbana ndi cholesterol. Imatha kutsitsa cholesterol mwa odwala omwe samathandizidwa ndi zakudya zapadera komanso mankhwala ena ochepetsa lipid. Mankhwalawa ali ndi zotsatirapo zake, zotsatira za kayendetsedwe kake zimawonekera patatha masiku angapo, ndipo phindu lalikulu limapezeka pambuyo mwezi umodzi wamankhwala.

Ubwino wa gemfibrozil ndizotsatira zochepa zoyipa komanso kuthekera kugwiritsa ntchito mankhwala ocheperako poyerekeza ndi mlingo wa mankhwala a tsiku ndi tsiku osaposa 0.6-0.9 g). Mtengo wapakati wa gemfibrozil ku Russia ndi ma ruble 1,500.

Fenofibrate mu kapangidwe ka mankhwala (Lipantil, Tricor) amagwiritsidwa ntchito nthawi zambiri kuti achepetse cholesterol mwa odwala matenda a shuga. Kafukufuku wachipatala awonetsa chiopsezo chochepetsetsa cha zovuta za anthu omwe ali ndi matenda ashuga omwe amagwiritsidwa ntchito pafupipafupi kukonzekera fenofibrate.

Kuphatikiza apo, mankhwalawa a gululi amatha kuchotsa uric acid mthupi, zomwe zimathandiza kwambiri odwala omwe ali ndi gout.

Kukonzekera kwa Fenofibrate kumakhala ndi zotsutsana: zimavulaza odwala omwe ali ndi matenda a ndulu ndipo sayanjana ndi mtedza. Mtengo pafupifupi wa Lipantil ndi Tricor ku Russia ndi ma ruble 1000.

Mankhwala ena otsitsa cholesterol

Ezetemib, mankhwala osagwirizana ndi mayamwidwe amkati mwa cholesterol, ndi amodzi mwa mankhwala omwe amachepetsa cholesterol yamagazi. Ku Russia, zimatenga ndalama kuchokera ku ma ruble a 1000 mpaka 2000, kutengera mtundu wa zovuta. Mankhwalawa ndi amitundu yatsopano yotsika ndi lipid, popeza ali ndi malingaliro osiyana pochita. Nicotinic acid (niacin) ndizomwe zimachokera zimagwiritsidwanso ntchito kuti muchepetse cholesterol.

Kuphatikiza pa kutsitsa kwa lipid, zinthuzi zili ndi zotsatira zina zambiri:

• imalepheretsa kukula kwa vitamini akusowa (pellagra),
• bwino kagayidwe ndi magazi,
• amachotsa zinthu zapoizoni m'thupi.

Zothandiza kuchokera ku niacin zimagwiritsidwa ntchito ngati chida chodziimira palokha komanso monga mankhwala. Nicotinic acid m'mapiritsi amagulitsidwa pansi pa mayina osiyanasiyana azamalonda, mtengo wa kulongedza mapiritsi 50 ku Russia sapitirira ma ruble 50.

Komanso, ndi cholesterol yambiri (yomwe nthawi zambiri imakhala yowonjezera pang'ono), akatswiri ena amalimbikitsa kutenga zowonjezera zosiyanasiyana zachilengedwe, komanso mankhwala azikhalidwe, monga infusions wa adyo. Zopindulitsa (komanso zovulazo) kuchokera ku chithandizo chotere sichikudziwika, chifukwa chake madokotala amalimbikitsa kugwiritsa ntchito othandizira pazakudya ndi othandizira pokhapokha pofuna kupewa.

Mndandanda wazakudya zothandizira kutsitsa cholesterol:

• Policosanol
• Omega Forte
• Doppelherz Omega 3,
• Tykveol
• lipoic acid
• SissPren.

Zotsika mtengo kwambiri pamenepa ndi lipoic acid - mu mankhwala azitha kugulidwa ma ruble 30-40. Mtengo wazakudya zina zothandizira kudya umachokera ku ma ruble 150 mpaka 600.

Zofunika! Kugwiritsa ntchito zinthu zonsezi kumamveka ngati kuchiritsa kwina (mankhwala ena kumachepetsa kuthamanga kwa magazi, kusintha kagayidwe), koma osagwiritsa ntchito cholesterol yayikulu.

Komabe, chithandizo ichi chikukula msanga.

Ubwino ndi zotsatira zoyipa za mankhwala opatsirana ndi lipid

Mwambiri, mphamvu ya mapiritsi a cholesterol m'thupi ndi yemweyo. Kuphatikiza pa kutsitsa mwachindunji cholesterol, mankhwala ochepetsa lipid ndi angapo:

• chepetsa kufooka kwa minofu ya mtima,
• Sinthani magawo a magazi
• pumulani ndi kukulitsa makhoma amitsempha yamagazi.
• khalani ndi khola lokwanira la malo omwe ma atherosselotic plaques.

Mfundo yomaliza ndiyofunika makamaka kwa odwala omwe amayembekeza opaleshoni kuti achotse zolembera zazikulu pazotengera.

Zotsatira zomwe zidalembedwera mtsogolo zimakhudza thupi la wodwalayo, chifukwa chake amalangizidwa kwa odwala omwe ali ndi zolinga zotsatirazi:

• popewa kulowerera m'mitsewa yam'mimba kapena mitsempha yaubongo,
• popewa kudwala matenda a sitiroko (makamaka ndi mbiri ya matenda a stroko),
• kukonzanso pambuyo pathupi lakhungu,
• Kuchepetsa kukula ndi kuwongolera kwa ma atherosulinotic njira.

Mankhwala ochepetsa magazi a cholesterol amachepetsa chiopsezo cha matenda a mtima kwa odwala omwe ali pachiwopsezo cha matenda amtima.

Chifukwa cha kukulira kwa lumen ya mtima komanso kusintha kwa magawo a magazi, chiwopsezo cha matenda amtima chimachepetsedwa kangapo, chomwe chimatsimikiziridwa ndi machitidwe azachipatala ndi zaka zambiri zamaphunziro azachipatala zamankhwala.

Ngakhale mutakhala ndi maubwino angapo komanso nthawi zambiri pakufunika kugwiritsa ntchito mankhwala kuti muchepetse cholesterol, ikhoza kukhala yovulaza thanzi lanu. Zotsatira zoyipa zimakhala ndi chiwopsezo chachikulu chowonetsedwa ndi kugwiritsidwa ntchito kwa nthawi yayitali, mwa okalamba, mwa anthu omwe ali ndi chitetezo chamthupi chofooka komanso matenda osakhazikika.

1. Nthawi zambiri mukamagwiritsa ntchito mankhwala omwe amachepetsa cholesterol, odwala amayamba kupweteka minofu yofanana ndi zomverera za matenda omwe ali ndi kachilombo ka fuluwenza. Wodwalayo akumva ululu wopweteka. Nthawi zina, kuwonongeka kwa minyewa kumatha kuchitika ndikutulutsa mapuloteni a myoglobulin m'magazi, omwe amachititsa kuti minyewa iyambe kulephera.
2. Zotsatira zodziwika bwino zoyipa ndizovuta zamkati zamanjenje: kusokonezeka kukumbukira ndi kuganiza. Zizindikiro ndizofanana ndi matenda a Alzheimer's - wodwalayo amayamba kuiwala zochitika zomwe zachitika (mwachangu amaiwala ngati adadya, adatenga mankhwala), akumana ndi zovuta munthawi komanso nthawi (wotayika ngakhale m'malo omwe amakhala, sanatchule mayina nthawi ya tsiku, tsiku la lero, mwezi) , imaleka kuzindikira anthu omwe amakhala pafupi naye. Nthawi zambiri, mavuto ngati amenewa amapezeka mwa anthu omwe ali ndi stroko.
3. Kuphatikiza apo, kuchuluka kwa ma enzymes a chiwindi m'magazi kumatha kuchuluka, zomwe zimayambitsa kusokonezeka kwa ntchito yake. Pakakhala vuto la chiwindi, mankhwalawa sangathenso kuchotsedwa m'thupi, zotsatira zake zowopsa zimawonjezeka ndipo kuzungulira kwina kumatseka. Kuti izi zitheke, patatha mwezi ndi theka kuyambika kwa makonzedwe, ndikofunikira kuyesa mayesero a chiwindi, ndikubwereza kamodzi miyezi itatu. Zotsatira zikamakulirakulira, mankhwalawo amachotsedwa.

Zowonjezereka ndizovuta zomwe zimabwera chifukwa chokhala ndi ma statins, monga:

• mutu
• nseru
• zovuta zam'mimba
• chifuwa
• kuchuluka kwa mphumu.

Kwenikweni, zotulukazi zimakhudzana ndi tsankho lomwe limagwiritsidwa ntchito popanga mankhwala.

Kodi mwakhala mukuvutitsidwa kwanthawi yayitali ndimutu, migraines, kupuma movutikira pang'ono, komanso kuphatikiza zonsezi zotchulidwa HYPERTENSION? Kodi mukudziwa kuti zizindikiro zonsezi zimawonetsa kuchuluka kwa cholesterol m'thupi lanu? Ndipo zomwe zimafunika ndikubwezeretsanso cholesterol.

Poona kuti mukuwerenga izi tsopano - kulimbana ndi matenda alibe kumbali yanu. Ndipo tsopano yankhani funsolo: kodi izi zikuyenera inu? Kodi zizindikiro zonsezi zingathe kuloledwa? Ndipo ndi ndalama ndi nthawi yochuluka bwanji zomwe "mudathira" kale pachipatala cha SYMPTOM, osati za matendawo omwe? Kupatula apo, ndikulondola kwambiri kupewetsa osati chizindikiro cha matendawa, koma matendawo omwe! Kodi mukuvomera?

Ichi ndichifukwa chake tikukulimbikitsani kuti muzolowere njira yatsopano ya E. Malysheva, yemwe adapeza chida chothandiza pantchito YOPHUNZITSA cholesterol yayikulu. Werengani mafunso ...

Ma regin anthawi yochepa

Pafupifupi 80% ya cholesterol imapangidwa ndi chiwindi ndi matumbo, ndipo sizimachokera ku chakudya. Chifukwa chake, ntchito yayikulu yothandizira kuchiritsa cholesterol imaperekedwa kwa mankhwala. Mankhwala a Statin ndiwotchuka kwambiri mu mankhwalawa.

Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.

• Kufunika kwa ma statins
• Malangizo pakuvomerezedwa
• Mitundu yodziwika bwino
• Simvastatin
• Lovastatin
• Crestor

Kufunika kwa ma statins

Statins imalepheretsa kugwira ntchito kwa ma enzymes a chiwindi, omwe amafunikira kuti mafuta a chiwindi azigwira bwino. Kuti muwonjezere mphamvu ya mankhwala, munthu amene akumwa ma statins ayenera kutsatira zakudya zapadera zopanda cholesterol. Kotero kuti cholesterol kuchokera ku chakudya sichimasokoneza "kulimbika" kwa mankhwalawa.
Statin imakhalanso ndi anti-yotupa. Chifukwa chake, amasiya kutupa kwawoko mu cholesterol atherosulinotic plaque mu lumen ya chotengera, akuletsa atherogenesis.

Malangizo pakuvomerezedwa

Ndi nthawi yanji ya tsiku yomwe kuli bwinoko kutenga ma statins? Kodi ziyenera kukhala zogwirizana ndi zakudya? Kutenga nthawi yayitali bwanji?

1. Ambiri cholesterol synthesis zimachitika usiku. Chifukwa chake, ma statins amalimbikitsidwa kuti atengedwe madzulo, maola angapo asanagone. Kutenga m'mawa kumachepetsa kugwira ntchito kwama statins ambiri.
2. Imwani kukonzekera ndi madzi omveka.
3. Osagwiritsa ntchito ma statins nthawi imodzi ndi mphesa kapena msuzi wake. Kugwiritsa ntchito nthawi yomweyo mankhwala a statins ndi mphesa (kapena msuzi wake) kumalepheretsa kagayidwe ka mankhwala. Ma Statin amadziunjikira m'thupi, zomwe zimapangitsa kuti pakhale mankhwala osokoneza bongo ambiri komanso zoyipa.
4. Kudya zakudya zokhala ndi mafuta ochulukirapo a nyama kumathandizanso kuthana ndi ma statins.
5. Chosangalatsa ndichakuti kutenga ma statins kwa nthawi yayitali kumabweretsa kuchepa kwa cholesterol kosatha. Chifukwa chake, kudya kwazaka 5 kungayambitse kuchepa kwa cholesterol yamagazi mkati mwa zaka 20.
6. Pochiza ndi ma statins, tikulimbikitsidwa kuwunika nthawi zonse mafuta a cholesterol. Choyamba, pambuyo pa miyezi 1-3 ya kumwa mankhwalawa, kenanso pambuyo pa miyezi 1-2 kuyambira nthawi yosinthira. M'tsogolomu, kuwunika kolesterol yamagazi kumachitika kamodzi pachaka, ngati palibe chisonyezo chapadera.
7. Muyenera kutenga ma statin kwa nthawi yayitali. Kugwiritsa ntchito kwakanthawi kochepa sikothandiza.
8. Kugwiritsidwa ntchito kwa warfarin ndi ma statins kungathe kuyambitsa zotsatira zoyambira ndikukulitsa mwayi wokhetsa magazi.

Simvastatin

Mankhwala awa ndi mankhwala. Ndiye kuti, kuti chikhale chinthu chogwira ntchito, chimayenera kusinthidwa ndimitundu yambiri yomwe imapezeka ndi thupi likalowa m'thupi. Adziwonetsa yekha chifukwa chokhoza kutengeka msanga komanso kukhala ndi mphamvu yochizira.

Mankhwalawa akuwonetsa momwe sanayambire kuposa masabata angapo atayambitsa makonzedwe ake. Malinga ndi mayeso a labotale, kusintha kwakung'ono koma kowonekeratu kumawonedwa pakatha mwezi umodzi kapena iwiri.

Simvastatin imachoka m'thupi mwachangu. Pakatha maola 12, thupi limayamba kukhala 95%. Chifukwa chake, amadziwitsidwa pamaso pazambiri za mafuta m'thupi a chiwindi: usiku. Amamwa piritsi limodzi patsiku. Palibe kulumikizana ndi kudya ndikofunika kumamatira.

Simvastatin tikulimbikitsidwa kuti ayambe kulandira chithandizo chokwanira ndi Mlingo yaying'ono, pang'onopang'ono ukuwonjezeka kwa mulingo woyenera. Nthawi zambiri Mlingo wa 20 mg ndiwofunikira kwambiri.

Lovastatin

Mankhwalawa amakhalanso ndi mankhwala osokoneza bongo. Zotsatira zamankhwala zimawonekera pokhapokha masabata angapo atavomerezedwa. Zimakhala zochuluka pakatha mwezi ndi theka. Mosiyana ndi simvastatin, mankhwalawa amalowetsedwa pang'onopang'ono. Amayamwa pang'onopang'ono m'matumbo ngati mutamwa mopanda kanthu. Zake bioavailability ndi 30% yokha. Pambuyo maola angapo, kuyika kwake kumakhala kokwanira. Ndipo pambuyo pa tsiku ndi 10% yokha yoyambayo.

Monga ma static ena, amatengedwa kamodzi patsiku. Muyenera kumwa mankhwalawa nthawi yamadzulo. Chithandizocho chimayamba ndi mlingo wochepa, womwe kenako umayamba kuwonjezeka. Kusintha kwa Mlingo kumachitika kamodzi masabata angapo. Mlingo waukulu (80 mg) ungagawidwe pawiri.

Mlingo wapamwamba woterewu umatheka pokhapokha ngati pali mankhwala enaake a monotherapy. Ngati mankhwala a antiholisterinemic amachitika ndi nicotinic acid kapena ma fiber nthawi yomweyo, ndiye kuti mlingo wa Lovastatin sayenera kupitirira 20 mg.

Kumwa mankhwalawa ndikosiyana pochiza ndi ma statin ena. Ndiwothandizanso ngati atatengedwa nthawi ina iliyonse masana, osati madzulo, monga ena oimilira gulu lino.

Pofika nthawi yakudya, salinso wokhathamira. Koma zofunikira pakutsatira zakudya za anticholesterol zimatsalira. Monga lamulo, tikulimbikitsidwa kuti muyambe kumwa Krestor ndi mlingo wochepa wa 5 kapena 10 mg 1 nthawi / tsiku. Pakatha mwezi umodzi, mlingo umatha kuchuluka.
Nthawi zambiri siyani kumwa 20 mg. Pafupipafupi, ndi kuchuluka kwa cholesterol m'magazi, 40 mg ya mankhwala ndi mankhwala. Mlingo woterewu ndi osavomerezeka kwa iwo omwe sanalandire cholesterolemia kale. Popereka mankhwala oterewa, lipid metabolism imayang'aniridwa pambuyo pa masabata 2-4.

Mlingo ndi malingaliro pa kugwiritsa ntchito ma statins ndi amodzi pamodzi. Zomwe zimapangidwira zimadalira mphamvu ya mankhwala aliwonse, magawo a labotale a mbiri ya lipid, mkhalidwe wa wodwalayo ndi kuopsa kwa atherosulinosis. Chofunikanso ndi zaka, jenda, ma pathologies omwe amagwirizana. Chofunika kwambiri ndikofunikira kwa wodwalayo kukhala nthawi yayitali, komanso kugwiritsa ntchito mankhwalawa kwa moyo wonse.

Mapiritsi otsitsa cholesterol yamagazi ndikutsuka mitsempha yamagazi

Anthu ambiri ali ndi mavuto azaumoyo omwe amakhudzana ndi misempha. Chifukwa chake, muyenera kudziwa zomwe mapiritsi a cholesterol alipo komanso momwe amagwirira ntchito.

Anthu akapeza cholesterol yayikulu m'magazi awo, anthu ambiri amafunsa kuti: "Kodi mapiritsi a cholesterol ndi othandiza kapena ayi?" Kumwa mankhwala omwe dokotala am'patsa amathandizira kubwezeretsa m'mitsempha, m'mitsempha, ndi m'mitsempha, ndikuchotsa cholesterol plaque. Pamodzi ndi mapiritsi, kudya komanso kuchita masewera olimbitsa thupi ndizofunikira. Chifukwa chake, ndikofunikira kudziwa kuti ndi mankhwala ati omwe amachepetsa cholesterol? Kodi ayenera kumwedwa bwanji?

Cholesterol yoyipa

Chofunikira mu magazi a munthu ndi cholesterol, yomwe imapezeka pafupifupi ziwalo zonse. Vitamini D ndi ma enzymes a mahomoni amapangidwa kuchokera pamenepo, ndipo amakhalanso chitetezo chokwanira. Cholesterol imathandizira kuti ubongo uzigwira bwino ntchito, chiwindi, minofu ndi minyewa. Komabe, kuchokera ku cholesterol yayikulu, ma pathologies owopsa a mtima amatuluka.

• imalepheretsa kuchulukana kwa ma hydrocarbons,
• kutenga nawo mbali popanga maselo am'mimba,
• imathandizira mapangidwe a bile ndi mahomoni opangidwa ndi ma adrenal glands,
• nawo kagayidwe,
• imasiyanitsa zingwe zam'mitsempha
• amathandiza kuyamwa vitamini D.

Enzyme imapangidwa ndi maselo a chiwindi, ndipo mapuloteni amasintha kudzera mu plasma. Zotsatira zake, maunyolo mawonekedwe, omwe pambuyo pake amasintha kukhala zigawo za lipoprotein zosiyanasiyana.

Zokhudza thupi zimatengera kapangidwe kazinthu izi. Ngati lipoproteins yotsika kwambiri (LDL) ilipo, ndiye kuti mafupa amapezeka m'matumba, pambuyo pake atherosulinosis. Ndi mkulu impermeability (HDL), kusinthana kolondola kwa cholesterol ndi asidi acids kumachitika, zomwe zimapangitsa kuti achepetse vuto la atherosulinosis.

Kuti mudziwe kuchuluka kwa chinthuchi, kuyezetsa magazi kwamomwe amachitika. Zizindikiro za miyambo zimasiyana pakati pa abambo ndi amai, zaka za munthu zimakhudzanso mtengo. Mu theka lolimba, cholesterol yokwezeka imawonedwa nthawi zambiri.

Kuwonjezeka kwa kuchuluka kwa osachulukitsa lipoproteins patatha zaka makumi asanu kumadziwika. Mwa akazi, chodabwitsachi chimamveka pa nthawi ya kusamba.

Zotsatira zake, njira zazikulu za pathological monga kusokonezeka kwa magazi muubongo zimatha kuchitika, zomwe nthawi zambiri zimayambitsa kuphwanya pansi kwa myocardial. Chifukwa chake, madokotala amapereka mankhwala othandizira kutsitsa cholesterol.

Ndi vuto la mtima kapena stroko, simungalole cholesterol kutukuka. Popeza kuyambiranso kwa chitukuko cha ma pathologies obwereza kungachuluke.

Ngakhale kuti cholesterol yapamwamba ndiyowopsa. Udindo wake pakachulidwe kakakulu, umatenga mbali pazinthu zonse zamitundu mitundu ndipo umafunika pa moyo wa thupi. Chifukwa chake, kuisunga kuti ikhale yachilendo ndikofunika, chifukwa amagwiritsa ntchito mankhwala ndikukhala ndi njira yolondola.

Chizindikiro chatsika

Zakudya Zabwino zimasankhidwa ndi adotolo, koma zimatengera:

• kusiya mowa, kusuta,
• Kuchepetsa mchere komanso zakudya zamafuta,

• Kuletsedwa kwamafuta am nyama, ndikwabwino kudya mafuta azamasamba,
• CHIKWANGWANI chamasamba, zophatikiza mafuta ndi ma polyunsaturated acid ziyenera kupezeka m'zakudya.

M'pofunika kusiyiratu masoseji ndi masoseji, makeke, makeke, masikono ndi ma muffin. Zakudya zopatsa thanzi sizingathandize kuchotsetsa kwambiri, komanso kukonza thanzi la munthu.

Ndikofunika kudziwa kuti 80% ya cholesterol imapangidwa m'chiwindi, ndipo 20% yotsala imapanga zakudya zomwe zimamwa. Chifukwa chake, kudya moyenera komanso moyenera kumathandizanso kuti matenda abwinidwe.

• kuwonda
• zolimbitsa thupi tsiku lililonse
• samalani kalori

• kusiya zizolowezi zoipa: mowa, kusuta,
• Pewani kupsinjika ndi mantha amanjenje.

Kuti muchepetse izi, mutha kugwiritsa ntchito zinthu potengera mankhwala azitsamba ndi zina zowonjezera pazamoyo. Mafuta ochulukirapo a Omega-3 polyunsaturated amalepheretsa kukula kwa magazi ndikukula kwa magazi kuti apange.

Pali nthawi zina pamene kutsatira zakudya, kusiya mowa ndikuchita masewera olimbitsa thupi kwa nthawi yayitali sikuthandizira kuchepa kwa cholesterol. Kenako dokotala amalimbikitsa kumwa mankhwala apadera kuti muchepetse cholesterol.

Mitundu ya Mankhwala

Masiku ano, pali mankhwala ambiri omwe amagwiritsidwa ntchito pa cholesterol yapamwamba. Amapezeka ngati mapiritsi ndi makapisozi. Dokotala, poganizira momwe wodwalayo alili, amasankha njira zothandiza kwambiri ndi zochepa zoyipa.

Mankhwala omwe amagwiritsidwa ntchito pa cholesterol yayikulu m'magazi amagawidwa m'mitundu ingapo.

1. Madera
2. Fibates.
3. Mankhwala omwe amasokoneza mayamwidwe a otsika osalimba a lipoprotein.
4. Nicotinic acid

Palibe mapiritsi abwinoko a cholesterol, mumtundu uliwonse wamankhwala pali zabwino zambiri komanso zovuta.

Mabedi amawoneka kuti ndiofala kwambiri; amachepetsa mafuta m'thupi mwachangu. Zilibe kuvulaza chiwindi, ngakhale kukhala ndi phindu pa izo. Komabe, ngati munthu ali ndi matenda oopsa a chiwindi, mankhwalawa amaletsedwa kugwiritsa ntchito, chifukwa zovuta kwambiri (kulephera kwa chiwindi) zimatha kuchitika.

Mndandanda wazithunzi zotchuka:

1. Simvastatin - Zokor, Vasilip.
2. Atorvastatin - Liprimar, Atoris.
3. Rosuvastatin - Crestor, Acorta.

Amphamvu kwambiri ndi ndalama zamagulu a Atorvastatin ndi Rosuvastatin, ndikulimbikitsidwa kuti muzimwa kamodzi usiku. Zilibe zotsatira zoyipa, choncho zimatha kuperekedwa kwa ana.

Mankhwala othandizira amaonedwa ngati osagwira ntchito. Zimakhudza kagayidwe ka lipid, makamaka kuchuluka kachulukidwe lipoprotein. Mankhwalawa amayikidwa pamaphunziro. Ma fimuti saloledwa kuphatikizidwa ndi ma statins. Iwo, monga mankhwala onse, amakhala ndi zotsatirapo zoyipa, chifukwa chake akapatsidwa, mawonekedwe amunthu amakhudzidwa.

Cholesterol mayamwidwe inhibitors (IAH) sakhala otchuka kwambiri, mutha kugula mtundu umodzi wa mankhwala (Ezetrol) mu pharmacy. Kutsitsa cholesterol kumatheka mwa kuletsa kuyamwa kwa lipids pamatumbo. Mankhwalawa alibe zotsatira zoyipa, ndipo amatha kuphatikizidwa ndi ma statins.

Nicotinic acid kapena niacin imapereka zotsatira zabwino. Imalepheretsa kupanga lipids. Komabe, nicotinic acid imangokhudza mafuta acids, kotero pamapeto pamaphunzirowa, microcirculation imadziwika. Monga lamulo, ndikudya ndalama pafupipafupi, zotsatira zotsitsa zimachitika.

Komanso, pakukhazikitsa lamulo logaya chakudya, ma sequenti a bile acids ayenera kumwedwa. Zothandiza kwambiri ndi cholestyramine ndi colestipol. Zikuwoneka kuti zimapanga ma asidi a bile ndikuzitengera kunjira zoyenera. Ndikusowa kwa iwo m'thupi, cholesterol imawonjezeka. Komabe, amaikidwa kangapo, chifukwa ali ndi zovuta zambiri.

Mafuta achilengedwe a polysaturated amachulukitsa oxidation m'magazi, potero amachepetsa milingo ya lipid. Zilibe zovuta, koma zotsatira zake sizichitika nthawi yomweyo, koma patapita nthawi yayitali.

Zowonjezera zimachepetsa triglycerides mu chiwindi ndikuchepetsa LDL. Zotsatira zamankhwala ndizotalikirapo, motero zimayikidwa kuwonjezera pa mankhwala akuluakulu. Mwachitsanzo, ngati pali chakudya chochepa m'zakudya za anthu, ndiye kuti kudya zakudya zamafuta owonjezera zakudya kungapangitse izi.

Zothandiza kwambiri kutsitsa cholesterol yamagazi ndi:

1. Omega Forte.
2. Tykveol.
3. Lipoic acid.
4. Mafuta opindika.

Mukamapereka mankhwala a cholesterol, makamaka dziwani:

• jenda ndi zaka
• kukhalapo kwa matenda oyamba ndi mtima,
• zizolowezi zoipa ndi moyo wawo.

Chifukwa chake, pali mndandanda wambiri wamapiritsi a cholesterol. Ndikofunikira kusankha chithandizo choyenera, mukuganizira zonse zomwe wodwalayo ali nazo, pokhapokha, kuchepa kudzakhala kopindulitsa.

Ndi dokotala yekhayo amene angakupatseni mankhwala oyenera ndi malingaliro ena omwe amafunikira.

Popewa, madokotala amalangiza pambuyo pa zaka 20 (kawiri zaka khumi) kuti awunikenso kuti adziwe kuchuluka kwa cholesterol. Popeza ndi ukalamba mwa anthu omwe akutsogolera moyo wolakwika, umatha kuchuluka. Ngati wodwala ali pachiwopsezo, ndiye kuti chizindikirocho chiyenera kuyang'aniridwa pafupipafupi, osachepera 1-2 pachaka.

Njira yogwiritsira ntchito "Atoris"

Atoris amatenga piritsi limodzi tsiku lililonse popanda kunena za chakudyacho. Lamulo lalikulu ndikumwa mankhwalawa panthawi yoyenera.

Ndikulimbikitsidwa kuti muyambe kulandira chithandizo ndi Atoris wokhala ndi 10 mg / tsiku. Ngati ndi kotheka, mulingo umachulukitsa mpaka 80 mg, koma muyenera kukumbukira kuti kuchuluka kwake kumachitika pokhapokha milungu 4 mutamwa mankhwalawa, ndiye kuti mankhwalawa sangasinthidwe osapitilira milungu 4 pambuyo pake. Onetsetsani kuti mwawona zomwe zili patsamba lazidziwitso mumayendedwe azinthu.

Ma statin achilengedwe

Njira ina yothanirana ndikumwa mapiritsi ikhoza kukhala zachilengedwe zachilengedwe.Nayi mndandanda wa zakudya zofala kwambiri ndi madera awo omwe kudya kwawo nthawi zonse kuli koyenera kutsitsa cholesterol yamagazi:

Zimapangira kuti muchepetse cholesterol

Monga ma statins, ma fiber amathandizira kuchepa kwa cholesterol. Komabe, mosiyana ndi zomwe zili pamwambapa, mankhwalawa ali ndi magwiritsidwe osiyanasiyana: amasintha kayendedwe ka cholesterol pamlingo wa jini.

Kutengera ndi fibroic acid, mitundu ingapo ya mankhwala imapangidwa:

1. Clofibrate
2. Gemfibrozil
3. Bezofibrat,
4. Cyprofibrate,
5. Fenofibrate.

Komabe, Tricor yekha wochokera ku gulu la fenofibrate ndiye amene akuimiridwa kwambiri ku Russia. Madokotala amatenga mankhwalawa pogwiritsa ntchito triglycerides kwambiri.

Zabwino komanso zoyipa za fibrate

Mwa zabwino za fibrate, ziyenera kudziwika kuti ndizothandiza kwambiri kuchepetsa triglycerides, komanso kuchepetsa chiopsezo cha matenda amtima. Komabe, kuyerekezera ma statins ndi ma fibrate awa, ziyenera kudziwika kuti omaliza samachepetsa kufa. Kuphatikiza apo, ndizoletsedwa mwamphamvu kutenga mafupa ndi ma statin palimodzi - izi zimawonjezera chiopsezo cha kuwonongeka kwa minofu.

Niacin kuti achepetse cholesterol

Niacin (nicotinic acid) amatchulidwa muyezo waukulu - magalamu 3-4 patsiku - njira yokhayo yochepetsera cholesterol. Mphamvu ya mankhwala pakhungu limadziwulula lokha mwachangu - masiku 3-4 atatha kudya. Mutha kukulitsa mphamvu za Niacin pophatikiza kudya kwake ndi ma statins, komabe, izi ndizodzaza ndi kufowoka kwa nkhope.

Ubwino waukulu wa mankhwalawa ndikuti umatsitsa magazi m'thupi. Kuphatikiza apo, chifukwa cha izo, kukoka kwa magazi m'mitsempha kumakhala bwino. Komabe, padakali chiopsezo cha mavuto ndi mtima. Zoyipa zake zimaphatikizanso waukulu Mlingo wa mankhwalawa, omwe amayenera kutengedwa kuti akwaniritse.

Cholesterol Absorption Inhibitors

Mtundu wa mankhwalawa siwofala ku Russia. M'magawo ogulitsa mankhwala mumatha kupeza oimira awiri okha: Ezetrol, omwe ali ndi ezetimibe, Inegi, okhala ndi ezetimibe ndi simvastatin. Makina a zochita za zoletsa ndikuti amamwa cholesterol kuchokera m'matumbo ndipo potero amachepetsa mulingo wake m'magazi.

Ngati zoletsa tikuyerekeza ndi mankhwala ena omwe amachepetsa cholesterol, ndiye kuti ndizokwera mtengo kwambiri. Komabe, sizogwira ntchito monga ma statins ndipo palibe umboni uliwonse pokhudzana ndi chiyembekezo cha moyo wawo womwe wapezeka. Ndipo phindu lawo lalikulu ndi kusavulaza, chifukwa chomwe iwo amatha kutengedwa ndi anthu omwe ali ndi matenda ena akulu (monga matenda a chiwindi). Limbikitsani zotsatira za mayamwidwe a cholesterol pakuwatenga pamodzi ndi ma statins.

Polyunsaturated Fatty Acids

Kuchepetsa cholesterol amaimiridwa kwambiri ndi mankhwala osokoneza bongo ndi zina zowonjezera (BAA). Mankhwala odziwika kwambiri m'gululi ndi mafuta a nsomba ndi Omacor. PUFAs imagwira ntchito molingana ndi mfundo iyi: amachepetsa kapangidwe ka triglycerides ndikuwonjezera mafuta acid oxidation receptors mu chiwindi. Komabe, ma PUFA okha ndi osagwira ntchito. Kwenikweni, iwo amatengedwa ndendende ngati chakudya chowonjezera pamodzi ndi ma statins kapena ma fiber.

Zina mwazabwino za mankhwalawa ndi chitetezo chake chachikulu. Zoyipa ndizochulukirapo kwambiri ngati mankhwala osiyana ndi kufunika kophatikizana ndi ena.

Bile acid sequestrants kuti muchepetse cholesterol

Chomwe chikuchitikira mankhwalawa ndikuti okhazikika amamangiriza ma bile acid, ndipo thupi, litazindikira kusowa kwa zinthuzi, limazipanga kuchokera ku cholesterol. Chifukwa cha kaphatikizidwe kameneka, cholesterol m'magazi amatsika kwambiri. Pali mankhwala 2 okha amtunduwu padziko lapansi: colestipol ndi cholestyramine, koma kugwiritsa ntchito kwawo sikuloledwa ku Russia.

Ubwino wodziwikiratu wokhazikika kwa izi: mankhwalawa samamwetsa magazi ndipo, motero, sasokoneza ntchito ya ziwalo zina. Pali zovuta zambiri:

• Kukoma koyipa
• Zotsatira zake zikuwoneka osapitirira mwezi umodzi,
• Kugwiritsa ntchito kwazaka zambiri kumayambitsa kuphwanya mayamwidwe amafuta ndi mavitamini,
• Ndizomwe zimayambitsa magazi ochulukirapo.

Chifukwa cha zoperewera zambiri ndi zabwino zochepa, othandizira sawagwiritsa ntchito kawirikawiri.

Chifukwa chake, pali mankhwala ambiri omwe amathandiza kuchepetsa magazi m'thupi. Mankhwalawa amasiyana mwanjira ndi kagwiritsidwe ntchito kochepetsera cholesterol, Mlingo ndi zoyipa. Mankhwala othandiza kwambiri ndi ma statins. Amatsatiridwa ndi fibrate, yomwe imayikidwa makamaka ngati chithandizo ndi ma statins sichili bwino (kwa matenda a chiwindi).
Ngakhale pali mankhwala ambiri osankhidwa ndi cholesterol yayikulu, adokotala okha ndi omwe amawalandira. Mankhwala omwe simunachite pano siabwino.

Kodi ndi chiyani

Mothandizidwa ndi ma statins, amachepetsa cholesterol yamagazi. Amachepetsa kupanga mevalonate. Izi zimaphatikizidwa ndikupanga cholesterol. Mankhwala oterowo amathandizira kukhazikika kwa mtima wamakhoma, amachepetsa magazi, komanso amachepetsa chiopsezo cha thrombosis.

Misonkhano yonse, cholesterol imagawidwa kukhala zabwino, zochulukirapo komanso zoipa kapena zotsika kwambiri za lipoprotein. Mothandizidwa ndi ma statins, kuchuluka kwa mtundu wachiwiri kumatsika, ndipo woyamba amakhala osasinthika, chifukwa amagwira ntchito zofunikira m'thupi.

Zotsatira zamankhwala omwe amapezeka ndi mankhwala zimatha kuwonekera patatha mwezi umodzi kuyambira chiyambi cha mankhwala. Amawonjezera kuthamanga kwa magazi kupita ku myocardium, kubwezeretsa mawonekedwe a mtima, kukulitsa malo amitsempha.

Zimagwira bwanji?

Ndi mankhwala a statin, milingo ya LDL imachepetsedwa ndi 20-50%. Hypocholesterolemic zotsatira zimatengera mlingo. Chophatikizika chilichonse cha mankhwalawa chimatsogolera kutsika kowonjezereka.

Makina a zochita za ma statins amatengera mphamvu zawo zoletsa ntchito ya HMG-CoA reductase. Njirayi imakhala yosinthira komanso kumwa. Kutsika kwa ntchito ya HMG-CoA reductase kumabweretsa kutsika kwa dimbolo la cholesterol mkati mwa maselo. Chifukwa cha izi, kuchuluka kwa zolandila za LDL pamitsempha ya hepatocyte kumawonjezera ndikuchulukitsa kuchuluka kwa tinthu ta LDL.

Statin imakhudzanso zotupa, heestasis, endothelial function. Chifukwa chake, m'maiko ambiri, mankhwalawa amaperekedwa kwa hypercholesterolemia, ngati zakudya sizinapeze zotsatira. Izi zimachepetsa mwayi wodwala matenda a mtima.

Gulu

Pali mitundu yosiyanasiyana yama statins yomwe imasankhidwa molingana ndi mawonekedwe angapo:

1. Mwa chiyambi. Pali makonzedwe achilengedwe omwe amapezeka mothandizidwa ndi bowa wotsika Aspergillusterreus, komanso theka lopangira - amapangidwa ndi kusintha kwa mankhwala kwachilengedwe.
2. Malinga ndi chinthu chachikulu chogwira ntchito. Statin amapangidwa ndi lovastatin, rosuvastatin, fluvastatin, atorvastatin, simvastatin.

Nthawi zambiri, makonzedwe opangira magawo amapangira, chifukwa ndi otetezeka komanso othandiza kwambiri.

Ma Statist amatulutsidwanso mibadwo. Zinthu zoyambira zokhala ndi lipid zotsitsa zimapezeka pazinthu zachilengedwe. Kutengera pa iwo, njira za gulu la lovastin zidapangidwa. Zosankha zina zonse zimapangidwa kuchokera ku zosakaniza zopangidwa. Sangabweletse mavuto.

M'badwo woyamba wama statins mulinso simvastatin ndi pravastatin. M'badwo wachitatu ukuyimiriridwa ndi gulu la fluvastatin. Izi ndi zotetezeka, ngakhale kuchitira ana. Mchere wa sodium ulipo mu kapangidwe kake, kamene kamapereka kuchepa kwa mafuta m'thupi.

Atorvastatin ndi wa m'badwo wachitatu. Kuphatikizika kwawo kumakhala kothandiza pa mtima wonse. Mankhwalawa amawonedwa ngati othandiza kwambiri komanso otetezeka.

Contraindication

Mankhwala a Statin saloledwa nthawi zonse. Iwo ali osavomerezeka:

1. Ngati impso sizigwira ntchito yawo.
2. Amayi oyembekezera komanso amayi oyembekezera omwe akuyamwitsa mwana.
3. Ngati kutenga pakati kukonzekera. Pa chithandizo, amayi amalangizidwa kugwiritsa ntchito njira zodalirika zolerera.
4. Ndi tsankho la munthu payekhapayekha.

Musanagwiritse ntchito, muyenera kukana mankhwala ena, chifukwa kuphatikiza kumatha kuyambitsa zovuta mu ntchito ya impso ndi chiwindi.

Zotsatira zoyipa

Ndikofunikira kutenga ma statins a cholesterol, ngati kudya sikuwongolera vutolo. Koma ngakhale mankhwalawa amapereka zabwino zambiri, palibe amene angatsimikizire kuti palibe zoyipa zomwe zimachitika.

Ndi kugwiritsa ntchito mankhwala kwa nthawi yayitali, rhabdomyolysis imayamba. Ndikusowa kolesterol, ntchito zamankhwala zimachepa, zimawonongeka, cretin phosphokinase m'magazi imakwera, ndipo kulephera kwa aimpso kumachitika.

Vutoli ndilosowa, koma muyenera kupita kwa dokotala pafupipafupi kuti mupeze panthawi yake. Kuti muchite izi, nthawi ndi nthawi mumaperekera magazi ku michere ya chiwindi ndikupanga phosphokinase.

Zochitika zina zoyipa zimapezekanso:

• kuwonongeka kwa chiwindi ndi impso,
• matenda amitsempha
• zotupa pakhungu zikuwoneka, kumva kuwala kwa dzuwa kumayamba,
• potency imaphwanyidwa,
• Tsitsi limatuluka
• kusokonezedwa ndi m'mimba;
• mutu ndi chizungulire, kukumbukira kumachepa,
• kupatsidwa zinthu za m'magazi kumachepetsedwa, zomwe zimawonjezera mwayi wokhetsa magazi.

Ndi cholesterol, ndibwino kutenga ma statins, chifukwa amachepetsa chiopsezo ku thanzi ndi moyo wa wodwalayo, zomwe zimachitika ngati munthu wapezeka ndi atherosulinosis. Koma adotolo ayenera kuthana ndi kusankha kwa mankhwalawo.

Ndani akusowa

Phindu ndi zovuta za ma statins za cholesterol zikukambidwabe ndi madokotala. Ngakhale zambiri zimakhala zabwino, sibwino kuti muzidya kwa nthawi yayitali, chifukwa izi sizingakhudze thupi. Amayamba kulandira mankhwala a statin ngati cholesterol singathe kuchepetsedwa ndi njira zina, komanso ngati pali ischemia. Gulu la mankhwalawa limafunsidwa ngati:

• chiwindi chimakhudzidwa ndi matenda osakhala oledzera wamafuta,
• matenda ashuga,
• kunenepa kwambiri kulipo
• Posachedwa panali vuto la kusokonekera kwa magazi kwamphamvu kwambiri,
• Kuchita opaleshoni yamitsempha ndi mtima kunachitika kuti magazi abweretse.

Mankhwala osokoneza bongo amathandizira kupewa kufalikira.

Momwe mungasankhire zoyenera

Ma Statistics amagulitsidwa ndi mankhwala, kotero simungathe kudzipatsa nokha. Dotolo amasankha mankhwalawa kutengera zaka komanso mtundu wa wodwalayo, mbiri yachipatala, zizolowezi zoyipa, komanso zotsatira zoyesa.

Ngati ndalama zilola, mutha kufunsa dokotalayo kuti akupatseni mankhwala oyambawo, chifukwa ma jenito samagwira ndipo nthawi zambiri amayambitsa zovuta.

Zinthu zomwe zikuyeneranso kuganiziridwanso. Kwa matenda a chiwindi, Pravastitin kapena Rosuvastatin amasankhidwa. Njira yoyamba imagwiritsidwa ntchito ngati pali vuto la kupweteka kwa minofu, chifukwa sizimapweteka minofu ndi mafupa a minofu.

Ngati pali matenda a chiwindi osachiritsika, musatchule Atorvastatin, chifukwa katundu wake amakulitsa matenda.

Zolemba ntchito

Phindu ndi zovuta za ma statins zimatengera kutsatira malamulo a kuvomerezedwa. Izi zikuyenera kutsogozedwa ndi maupangiri otsatirawa:

1. Imwani mankhwala usiku mutatha chakudya chatha.
2. Gwiritsani 20 mpaka 40 mg patsiku. Mlingo weniweni umasankhidwa poganizira thanzi la wodwalayo.
3. Munthawi yamankhwala, muyenera kuyang'anira bwino momwe muliri. Ngati palibe zotsatira, muyenera kuuza dokotala za izi. Adzalembera mlingo waukulu kapena kumwa mankhwala ena.

Mankhwala, mankhwala othandizira kapena kukonza mankhwalawa amagwiritsidwa ntchito. Mafuta a cholesterol akabwerera mwakale, amayamba kuchepa ndipo amayamba kukonza mankhwalawo.

Kwa okalamba, amasankha m'badwo wamakono wamankhwala, popeza ali ndi chiopsezo chochepa kwambiri.

Zina zomwe zimagwirizana ndi mankhwala

Statin sangathe kudya ndi mankhwala ena, chifukwa kuwonongeka kwa impso ndi chiwindi kumatha kuchitika. Zimakhudza:

• maantibayotiki ngati erythromycin, clarithromycin,
• njira zochizira matenda a fungus,
• calcium blockers mu mawonekedwe a verapamil,
• michere ya micro kapena michere,
• proteinase inhibitors (awa ndi mankhwala ochizira Edzi).

Komanso, mukamalandira chithandizo, sikulimbikitsidwa kumwa zipatso za mphesa ndi msuzi wa mphesa, chifukwa izi zimatha kubweretsa mavuto.

Kugwiritsa ntchito bwino

Masiku ano, ma statins okha ndi omwe amapangitsa kuti pasakhale zovuta zoteteza matenda a mtima, ngati ma cell omwe siamachiritso omwe amalimbana ndi atherosulinosis ndi osathandiza.

Mothandizidwa ndi ma statins, ma cholesterol amana omwe amakhala pamakoma amitsempha yamagazi amachotsedwa, zomwe zimathandiza kupewa zovuta zamagazi, thrombosis ndi zotsatirapo zonse zotsatirazi. Pogwiritsa ntchito mankhwalawa, malo osungirako mitsempha amakula, kuthamanga kwa magazi kumawonjezereka, arrhythmia ikudutsa, komanso kuwonongeka kwa zizindikiro za matenda a shuga kumachepa.

Ndemanga za mankhwalawa ndizabwino kwambiri, chifukwa ngakhale atakumana ndi zovuta, amathandizira kuthetsa mitsempha yamagazi, kukhazikitsa njira zoyambira zamthupi, komanso kuchepetsa thupi ngati munthu ali wonenepa kwambiri.

Mothandizidwa ndi ma statins, amathandizira kuchira pambuyo pa kulowerera kwa mtima wam'mimba, stroko, pulmonary embolism, kuchitapo kanthu kwa opaleshoni kuti akhazikitse shunts, stents, ndi angioplasty ya mtima.

Kodi ndizotheka kuchepetsa cholesterol yopanda ma statins

Ndikosatheka kutenga ma statins kwa nthawi yayitali kuti muchepetse cholesterol, chifukwa izi zimabweretsa zovuta. Chifukwa chake, kuti khazikike magwiridwe antchito, amayambira kudya.

Cholesterol ilipo yambiri mazira ndi nsomba zam'nyanja. Koma zoyambitsa zazikulu za cholesterol plaques ndi mafuta odzadza. Koma sangathe kudzipatula kwathunthu, chifukwa amaonetsetsa kuti chithokomiro chikugwira, mukungofunika kuti musamadye kwambiri. Ngati chakudyacho chili ndi zopatsa mphamvu 2000, ndiye kuti mafuta okwanira sayenera kupitirira 15 g.

Palinso zinthu zomwe zimatha kuchepetsa cholesterol yamagazi yoyipa. Katunduyu ali mu:

1. Kaloti. Kafukufuku akuwonetsa kuti kudya kaloti awiri pamwezi kumatsitsa LDL ndi 15%. Komanso masamba amathandizira kuchepetsa kukokomeza kwa hepatic ndi aimpso.
2. Tomato. Amakhala ndi ma lycopene ambiri. Mtunduwu amaonedwa ngati mankhwala a cholesterol, popeza 24 mg yake patsiku imachotsa gawo limodzi mwa magawo khumi a LDL. Kuti muchepetse mulingo wake, magalasi awiri a madzi a phwetekere patsiku ndikokwanira. Komanso, tomato ali ndi potaziyamu ambiri, omwe amakupatsani mphamvu kuti musunge minofu ya mtima.
3. Garlic. Alliin amapezekamo. Amapereka lakuthwa ndi kununkhira kwa adyo. Popeza alliin siabwino kwa thupi, ikamudya, imasandulika kukhala allicin, yomwe imachotsa cholesterol plaques.
4. Mtedza. Kafukufukuyu adapeza kuti kudya magalamu 60 a mtedza patsiku kumabweretsa kuchepa kwa cholesterol yonse ndi 5%. Nthawi yomweyo, LDL imakhala yochepera 7.5%. Chosangalatsa ndichakuti, pamene hypercholesterolemia yotchulidwa kwambiri, zimakhala bwino kuti mtedza uzichita. Vutoli limaperekedwanso ndi cholembera cha thupi, popeza anthu onenepa kwambiri amapindula kwambiri ndi mtedza. Kuphatikiza apo, mtedza wonse uli ndi mavitamini A ambiri, magulu B, E, komanso kufufuza zinthu monga potaziyamu, calcium, phosphorous, ndi chitsulo.Kugwiritsa ntchito mankhwalawa pafupipafupi kumachepetsa mwayi wokhala ndi dementia muukalamba komanso kugunda kwamtima mwadzidzidzi.
5. Nandolo. Kugwiritsa ntchito kwazomwe mukugulitsa makapu amodzi ndi theka patsiku kumakuthandizani kuti muchepetse cholesterol ndi 20% m'milungu yochepa. Nandolo ndizodzaza ndi mavitamini ambiri a B, omwe amapereka mphamvu yamanjenje, tsitsi labwino komanso kugona bwino.
6. Nsomba zonona. Ili ndi mafuta ochulukirapo a polyunsaturated. Amathandizira kuchotsa ma cholesterol amana.

Nsomba ndi nyama zimakhutitsa thupi ndi mapuloteni amanyama. Koma muzinthu zam'madzi mumakhala ulusi wocheperako, motero umakimbidwa mwachangu komanso osavuta kugaya. Komanso, nsomba zam'madzi zimakhala ndi zopatsa mphamvu zochepa, kotero ndizoyenera kwa iwo omwe akuvutika ndi mapaundi owonjezera. M'mapuloteni a nsomba, tauric acid imalepheretsa matenda a mtima ndi mitsempha yamagazi, komanso ma methanejeni a mitsempha. Ma taurine ochulukirapo mu nsomba zam'nyanja. Ilinso ndi phosphorous yambiri ndi fluorine, potaziyamu ndi selenium. Chifukwa chake, zinthu ngati izi ziyenera kukhalapo pakudya kwa munthu aliyense.

Chifukwa chake, ngati pali vuto la hypercholesterolemia, amalimbikitsidwa kuti akhazikitse zakudya zopatsa thanzi, idyani zakudya zabwino zowonjezera. Ngati kukana kwamafuta akudzaza sikupereka zotsatira, ndiye kuti mutembenukire kuma statins.

Mafunso Ofunsidwa Kawirikawiri

1. Kodi ma statins amatengedwa zaka zingati? Nthawi zambiri, mankhwalawa amalembedwa kwa anthu azaka za 50-60. Ndi mu m'badwo uwu pomwe anthu amayamba kuwonetsa atherosulinosis, chiwopsezo chachikulu cha matenda a mtima ndi stroko, ngakhale izi zimatha kuchitika ali aang'ono.
2. Kodi ndi cholesterol yotani yomwe imaperekedwa kwa ma statins? Statin siyingagawidwe ngati milingo yotsika kwambiri ya lipoprotein ifika 8,5 mmol / L kapena kuposa.
3. Kodi pali ma statins a cholesterol kupewa? Nthawi zambiri, mankhwalawa amagwiritsidwa ntchito kuti athetse vuto la hypercholesterolemia. Nthawi ndi nthawi, pakukonzekera, mankhwalawa amasinthidwa, ngati zikuyambiridwenso zimakhala zabwinobwino, ndiye kuti mankhwalawo amamwetsa pang'ono kuti aletse kuchuluka.
4. Ndi ma statins omwe amatengedwa bwino kwambiri mukakalamba? Okalamba amathandizidwa ndi atorvastatin, rosuvastatin, simvastatin. Nthawi zina amagwiritsa ntchito lovastatin, koma ichi ndi mankhwala ochepetsedwa, kotero, sichigwiritsidwa ntchito nthawi zambiri. Iliyonse ya mankhwalawa imathandizira cholesterol yotsika, imalepheretsa kugunda kwa mtima, kugunda kwa miyendo ndikuchepetsa kufa kwathunthu. Sankhani chida chachikulire kwa okalamba, kutengera kutengera komwe kumachitika mosavomerezeka.
5. Kodi ndimatenga ma statins nthawi yayitali bwanji? Njira yochizira ndi mankhwala ndi yayitali. Nthawi zina amadya kwa zaka zingapo, koma osapitirira zaka 5, popeza kugwiritsidwa ntchito nthawi yayitali kumayambitsa impso ndi chiwindi.

Ma Statin - ndi chiyani

Statins ndi gulu la mankhwala omwe amapangidwa kuti achepetse cholesterol yamagazi. Koma mankhwalawa samukhudza mwachindunji. Zimakhudza chiwindi, kulepheretsa kubisika kwa enzyme yomwe imakhudzidwa ndikupanga cholesterol.

Mu thupi la munthu muli ziwalo zake - lipoproteins. Amakhala ndi malo ochulukirapo komanso otsika. Ngati njira za metabolic sizisokonezeka, ndiye kuti ma lipoprotein sakuwaika pachiwopsezo chaumoyo. Koma kuphatikiza cholesterol yochulukirapo kumathandizira kupanga mapangidwe am'madzi, omwe amatsogolera pakupanga matenda oopsa.

Statin cholinga chake ndi kuchepetsa kuchuluka kwa cholesterol chonyamula zimakhala. Nthawi yomweyo, kuchuluka kwa zolimba kwambiri za lipoprotein receptors pa hepatocytes kumachulukana. Mwakutero, amasamutsa cholesterol mbali inayo - kuchokera kukayenda kwa magazi kupita ku chiwindi. Chifukwa cha mankhwalawa, kupanga mafuta m'thupi kumapangidwanso. Kugwiritsa ntchito kwawo kumapangitsa kuti zinthu zake zizikhala bwino.

Zofunika! Cholesterol choti mutenge ma statins? Ndizofunikira kwa munthu wokhala ndi chizindikiro pamwamba pa 5 mmol / l. Pambuyo pang'onopang'ono infarction, mu kwambiri matenda a mtima, chidwi cholesterol zili amachepetsa.

Atorvastatin

Awa ndi mapiritsi othandiza kwambiri omwe amathandizira kuchepetsa cholesterol komanso kupewa mavuto ndi mtima. Malinga ndi ziwerengero, kugwiritsa ntchito Atorvastatin kumathandiza kuchepetsa chiopsezo cha stroke ndi 50%. Mtengo wa mankhwalawa pafupifupi ndi 200 UAH, kapena ma ruble 450.

Mankhwalawa amalembera mitundu yosiyanasiyana ya hypercholesterolemia, makamaka osakanikirana ndi mtima atherosulinosis ndi matenda a shuga. Vasilip amagwiritsidwa ntchito popewa kugunda kwa mtima komanso sitiroko. Mtengo wapakati wa mapiritsiwa ndi 150 UAH., Kapena ma ruble 320. Awa ndimapiritsi otsika mtengo koma ogwira mtima omwe amathandizira kuchepetsa magazi m'thupi.

Ichi ndi chithunzi chonse cha atorvastatin. Zimalepheretsa mapangidwe a cholesterol kuchokera ku lipids. Atoris imathandizanso kukulitsa kwambiri cholesterol "yabwino". Mutha kugula mapiritsi a pafupifupi UAH 230, kapena ma ruble 500.

Mankhwalawa amachepetsa mafuta m'thupi. Ichi ndi mankhwala othandiza omwe ali ndi mavuto ochepa. Roxer amatchulidwa kuti apewe matenda a mtima okalamba. Mtengo woyenerera wa chinthu ichi ndi 90 UAH, kapena ma ruble 250.

Mankhwalawa amagwiritsidwa ntchito poteteza cholesterol. Iwo akuphwanya kuphwanya chiwindi, hepatitis, kwambiri aimpso kulephera. Chifukwa cha zovuta, Rosart ayenera kumwedwa kutsatira malangizo. Mutha kugula mankhwalawa pamasitolo pamtengo wokwanira wa 170 UAH, kapena ma ruble 400.

Chimodzi mwazida zotsika mtengo komanso zothandiza. Muli rosuvastatin, ali ndi mphamvu yokhalitsa. Kuti muchite bwino, Mertenil ayenera kumwedwa pamodzi. Mtengo pafupifupi wa mankhwalawo ndi 150 UAH, kapena ma ruble 300.

Zimathandizira kuti muchepetse cholesterol. Amagwiritsidwanso ntchito kupewa matenda a mtima ndi magazi a mtsempha wamagazi, atherosulinosis. Imakhala ndi zotsutsana zingapo komanso zoyipa, chifukwa chake zitha kugwiritsidwa ntchito pokhapokha ngati madokotala akuwonetsetsa, mosamala. Mutha kugula Rosucard pafupifupi 180 UAH., Kapena ma ruble 420.

Rosuvastatin

Ichi ndi chimodzi mwamphamvu kwambiri chogwiritsira ntchito cholesterol yotsitsa. Rosuvastatin ali ndi mphamvu yokhalitsa. Mutha kugula mapiritsi pafupipafupi a 220 UAH., Kapena ma ruble 500.

Ndikofunikira kukumbukira! Statin yotetezeka imathandiza dokotala kuti azisankha, potengera mawonekedwe amthupi la wodwalayo ndi matenda ena okhudzana nawo!

Zomwe zimagawidwa ndi ma statins

Pali njira zingapo zopatulira ma statins:

1. Kwa mibadwo: m'badwo woyamba, wachiwiri, wachitatu komanso wotsiriza.
2. Zoyambira: zopangidwa, zopangira theka komanso zachilengedwe.
3. Malinga ndi kuchuluka kwa yogwira zinthu: mlingo waukulu, pakati Mlingo wochepa komanso wochepa.

Gawoli lotsirizalo ndilosavuta kwambiri, popeza ma statin ndi omwe amapatsidwa mitundu yambiri.

Ubwino ndi kuvulaza kwa ma statins

Mankhwala m'gululi ali ndi zabwino zingapo. Izi zikuphatikiza:

1. Kuchepetsa chiopsezo cha kufa ndi matenda a mtima.
2. Kuopsa kwa vuto la mtima kumachepetsedwa ndi 30%.
3. Pogwiritsa ntchito ma statins nthawi zonse, cholesterol imachepa ndi 40-55%.
4. Madera a m'badwo waposachedwa alibe zinthu zapoizoni. Zotsatira zoyipa zimawonedwa nthawi zina.
5. Ma Statin ali ndi ma fanizo ambiri. Aliyense akhoza kudzisankhira mankhwala oyenera pa mtengo wake.

Kuvulaza kwa statins kumachitika chifukwa chakuti zimatha kuyambitsa matupi athu:

• masinthidwe osinthika amtopola, nkhanza, mphwayi, mantha,
• kufooka kwa thupi,
• mitsempha yopanda yotupa,
• kusokoneza kwam'mimba,
• kupweteka m'malo olumikizirana mafupa ndi minofu,
• kuchepa kwa ndende.

Ma Statin amathanso kubweretsa vuto la metabolic, chifukwa chake ayenera kugwiritsidwa ntchito mosamalitsa kutsatira malangizowo.

Pomaliza

Ngati magazi a otsika kachulukidwe lipoproteins atakwera, izi zimabweretsa Kukula kwa atherosulinosis. Kuti muthane ndi hypercholesterolemia, zakudya zimayikidwa koyamba, ngati sizithandiza, ma statins amagwiritsidwa ntchito. Pali zinthu zachilengedwe komanso zopangidwa. Njira yachiwiriyi imakhala yotetezeka, chifukwa zovuta zimayamba kuchepa. Ngati mutenga ma statins molondola, mutha kuchepetsa chiopsezo chokhala ndi matenda a mtima, stroke, kugunda kwamtima. Koma kuphwanya mlingo ndi mlingo wa mankhwalawa kumayambitsa zoopsa monga rhabdomyolysis. Pofuna kuwonjezera katundu pa chiwindi ndi impso, simungathe kuwaphatikiza ndi maantibayotiki, ma antifungal agents, komanso mankhwala a AIDS.