Ndemanga zapamwamba za cholesterol zapamwamba

Zidachitika kuti pakuyang'ananso magazi motsatira magazi, ndidapeza cholesterol yokwanira, osati yambiri, osati 7.3.

Cholesterol okwera ndi chiwopsezo cha kugunda kwa mtima ndi mikwingwirima, chifukwa cholesterol imakonda kumamatira kukhoma lamitsempha yamagazi ndikuchepetsa lumen yawo, kuphatikiza apo, magazi omwe ali ndi cholesterol yambiri amakhala owonekera. Zinthu ziwiri izi zitha kupangitsa kuti chotchinga kapena chotumphuka. Zachisoni ...

Wotsogolera, malinga ndi zotsatira za mayeso, adandiwuza chithandizo - ndikumwa mankhwala kuti ndichepetse cholesterol Atoris, pa mlingo wa 10 mg, kamodzi patsiku ndikuyambiranso kuwunika kwa masabata awiri atatha mankhwalawa.

• Atoris (Atorvastatin) ndi mankhwala ochokera pagulu la ma statins.
• Wopanga - Krka, Slovenia
• Chiwerengero cha mapiritsi pa paketi iliyonse - 30 ma PC.
• Mtengo - 358 rubles

Mapiritsiwo ndi ochepa, oyera

Atoris amalembedwa kuti akhale ndi cholesterol yayikulu kuti achepetse cholesterol kuti ikhale yachilendo, ndikuyisunga malinga ndi malire.

Zizindikiro

• hyperlipidemia yoyamba Mitundu ya IIa ndi IIb malinga ndi gulu la Frederickson, kuphatikizapo polygenic hypercholesterolemia, Hyperlipidemia yosakanikirana, heterozygous achibale hypercholesterolemia, kutsitsa mulingo wazonse cholesterol, apolipoprotein B, LDL cholesterol, triglycerides m'magazi
• mabanja homozygous hypercholesterolemia, kutsitsa mulingo wazonse cholesterol, apolipoprotein B, LDL cholesterol,

Contraindication

• mafupa amisempha
• Hypersensitivity kuti atorvastatin, zosakaniza zina za Atoris, kapena kuphatikiza kwake,
• kulephera kwa chiwindi,
• matenda a chiwindi mu pachimake gawo (kuphatikizapo chidakhwakapena yogwira nthawi zonsechiwindi,
• lactase akusowa, lactose tsankho ndi shuga-galactose malabsorption syndrome,
• Cirrhosis ochokera kosiyanasiyana
• malo okwera hepatic transaminases Zachidziwikire, zomwe ndizochulukirapo kuposa katatu,
• wazaka 18
• nthawiyoyamwitsandi mimba.

Monga ananenera katswiri wothandizira, ndimatenga Atoris 10 mg kamodzi patsiku. Mutha kumwa mankhwalawa nthawi iliyonse, koma muyenera kuchita nthawi yomweyo.

Patatha milungu iwiri ndidapereka kuyesa kwa magazi, adawonetsa kuti cholesterol level yanga m'magazi mwanga idachepa ndikukhala yabwinobwino - 5.7.

Mafuta a cholesterol m'mwazi

Kuti mukhale ndi zotsatira zabwino, ndinapatsidwa mwayi wopitiliza kumwa Atoris pamilungu imodzimodzi, ndikuchepetsa mlingo mpaka 5 mg kamodzi patsiku.

Zachidziwikire, ndizosavuta, kumwa mapiritsi ndi voila, mayesowa ndi abwinobwino. Koma tikumvetsa kuti ngati cholesterol imakwezedwa, ndiye kuti muyenera kusintha zakudya zanu. Masoseji abwino, brisket, waffles, ndinali bwino nanu!

Atoris wa mankhwala adachita zonse zomwe ndimayembekezera kwa iye. Anachepetsa mwachangu kuchuluka kwa cholesterol m'mwazi ndipo sizinandibweretsere zovuta kapena zovuta zilizonse, paketi imodzi inali yokwanira ine kwa mwezi umodzi wotenga.

Kugwiritsa ntchito mapiritsi, mutha kutsitsa cholesterol mwachangu, koma kuisunga pamalo otetezeka kuli bwino ndikudya koyenera, chifukwa kumwa mapiritsi amoyo mwanjira ina sikwabwino.

Tithokoze aliyense amene wawerenga ndemanga yanga, khalani ndi tsiku labwino!

Ma Status: momwe amathandizira, zikuwonetsa komanso kuphwanya, kuwunika kwa mankhwala, zomwe zingachitike

Kwa zaka zambiri osavutika ndi CHOLESTEROL?

Mutu wa Bungwe: “Mudzadabwa momwe zimakhalira zosavuta kuchepetsa mafuta m'thupi mwakumwa tsiku lililonse.

Cholesterol, kapena cholesterol, ndi chinthu chomwe chimagwira ntchito zofunika mthupi la munthu. Izi zikuphatikiza:

• Kutengapo gawo ngati chida chomanga cha pafupifupi maselo onse amthupi, popeza mamolekyu a cholesterol amaphatikizidwa ndi membrane wa cell ndikupatsa mphamvu, kusinthasintha ndi "fluidity",
• Kutenga nawo gawo pa chimbudzi ndi mapangidwe a bile acids wofunikira pakuwonongeka ndikufinya kwa mafuta m'matumbo am'mimba,
• Kutenga nawo gawo pakapangidwe kwamahomoni m'thupi - mahomoni a adidal a gren ndi ma mahomoni ogonana.

Kuchuluka kwa cholesterol m'magazi kumabweretsa kuti ma molekyulu ake owonjezera amatha kumuyika pazenera za mitsempha yamagazi (makamaka mitsempha). Mapangidwe a atherosulinotic amapangidwa omwe amasokoneza magazi oyenda kudzera mu mtsempha wamagazi ndipo nthawi zina, pamodzi ndi zigawo za magazi zomwe zimamangiriridwa, zimatseka lumen ya chotengera, zomwe zimathandizira kukulitsa kugunda kwa mtima komanso sitiroko.

Muyezo wa cholesterol yathunthu m'magazi a munthu wamkulu sayenera kupitirira 5.0 mmol / l, mwa odwala omwe ali ndi matenda a mtima osaposa 4.5 mmol / l, komanso kwa odwala omwe ali ndi infration ya myocardial osaposa 4.0 mmol / l.

Kodi ma statins ndi chiyani ndipo amagwira ntchito bwanji?

Muzochitika zomwe wodwalayo ali ndi chiwopsezo chambiri chotenga myocardial infarction chifukwa cha atherosulinosis ndi cholesterol metabolism, amamuwonetsa kugwiritsa ntchito mankhwala ochepetsa lipid ochepetsa nthawi yayitali.

Statins ndi hypolipidemic (lipid-kutsitsa) mankhwala, limagwirira zake zomwe tikulepheretsa enzyme yomwe imalimbikitsa kupanga cholesterol. Amagwiritsa ntchito mfundo ya "palibe enzyme - palibe cholesterol." Kuphatikiza apo, chifukwa cha njira zosadziwika, amathandizira kusintha kwa mitsempha yamkati yowonongeka pamitsempha pomwe atherosulinosis ikadali yosatheka kuzindikira, koma mawonekedwe a cholesterol pamakoma ayamba kale - kumayambiriro kwa atherossteosis. Amathandizanso pakutsata magazi a magazi, kutsitsa mamasukidwe akayendedwe, chomwe ndichinthu chofunikira chomwe chimalepheretsa mapangidwe amwazi ndi kudziphatika kwawo pamapepala.

Zothandiza kwambiri pano ndizodziwika bwino monga m'badwo waposachedwa kwambiri wama statins, okhala ndi atorvastatin, cerivastatin, rosuvastatin ndi pitavastatin ngati chinthu chogwira ntchito. Mankhwala a m'badwo waposachedwa samangoletsa kuchuluka kwa cholesterol "yoyipa", komanso kuwonjezera "zabwino" m'magazi. Awa ndiwo ma statin abwino kwambiri mpaka pano, ndipo momwe amagwiritsidwira ntchito amapezeka kale mwezi woyamba wogwiritsidwa ntchito mosalekeza. Statin amalembedwa kamodzi patsiku usiku, kuphatikiza kwa iwo piritsi limodzi ndi mankhwala ena a mtima ndikotheka.

Kugwiritsira ntchito mwaulere kwa ma statins popanda kufunsa dokotala sikovomerezeka, popeza musanamwe mankhwalawa, ndikofunikira kudziwa kuchuluka kwa cholesterol m'magazi. Kuphatikiza apo, ngati cholesterol yotsika kuposa 6.5 mmol / l, pakatha miyezi isanu ndi umodzi muyenera kuyesa kutsitsa ndi zakudya, moyo wathanzi, ndipo pokhapokha ngati izi sizikuyenda bwino, dokotalayo amasankha kukhazikitsidwa kwa ma statins.

Kuchokera pazomwe mungagwiritse ntchito ma statins, mutha kuwunikira mfundo zazikulu:

Zisonyezo za ma statins

Chizindikiro chachikulu ndi hypercholesterolemia (cholesterol yayikulu) ndi kusachita bwino kwa njira zosagwiritsa ntchito mankhwala osokoneza bongo komanso cholowa chamagulu (cholowa) hypercholesterolemia ndi kusagwira bwino kwa zakudya.

Kukhazikitsa ma statins ndikofunikira kwa anthu omwe ali ndi hypercholesterolemia yomwe imakhudzana ndi matenda otsatirawa, chifukwa kugwiritsa ntchito kwawo limodzi ndi mankhwala ena omwe adalembedwa ndi adokotala kumachepetsa chiopsezo cha kufa mwadzidzidzi kwamtima:

• Anthu opitirira 40 omwe ali ndi chiwopsezo chachikulu cha matenda amtima,
• Matenda a mtima, angina pectoris,
• Myocardial infaration
• Opaleshoni ya aorto-coronary bypass kapena stent yokhazikitsidwa kwa myocardial ischemia,
• Stroko
• Kunenepa kwambiri
• Matenda a shuga
• Milandu yakufa mwadzidzidzi kwamtima wa pachibale pafupi ndi zaka 50.

Contraindication

Contraindication zimaphatikizira chiwindi ntchito (hepatitis, cirrhosis) mu gawo yogwira, thupi lawo siligwirizana ndi kale mankhwala. Ma Statist sayenera kutengedwa ndi amayi apakati komanso oyembekezera, komanso azimayi azaka zaubala omwe sagwiritsa ntchito njira zodalirika zakulera. Ma Statin samakhudzanso mitundu ina ya kagayidwe (protein, carbohydrate, purine metabolism), kotero, amatha kugwiritsidwa ntchito mwa odwala omwe ali ndi matenda ashuga, gout ndi zina zomwe zimafanana ndi matenda.

Zotsatira zoyipa

Osachepera 1% ya odwala omwe amatenga ma statins kwa nthawi yayitali ndikupitiliza kugona, kusokonezeka kwa minofu, kufooka kwa minofu, kuchepa kwa makutu, kuchepa kwa vuto, mtima, kuchepa kwambiri komanso kuwonjezeka kwa kuthamanga kwa magazi, kuchepa kwa magazi m'magazi, mphuno. , kupweteka kwam'mimba, nseru, chosakhazikika, kukoka mobwerezabwereza, kuchepa kwam'mimba, kupweteka kwa minofu ndi mafupa, rhabdomyolysis (kuwonongedwa kwa minofu minofu), kuchuluka thukuta, thupi lawo siligwirizana.

Oposa 1% ya odwala amakhala ndi chizungulire, nseru, mtima, kupuma, kutsekeka kwa mphuno, zotumphukira edema, chidwi chamtundu wa dzuwa, kuwala kwa pakhungu - kuyabwa, redness, chikanga.

Kodi ma statins amatha kuphatikizidwa ndi mankhwala ena?

Malinga ndi malingaliro a WHO ndi American Mtima Association, ma statins ndi mankhwala ofunikira pakuthandizira matenda a mtima omwe ali ndi chiwopsezo chachikulu cha zovuta komanso kuphwanya kwa myocardial. Kukhazikitsa mankhwala okha kuti muchepetse cholesterol sikokwanira, chifukwa chake mankhwala ofunika amaphatikizidwa muzoyimira - awa ndi beta - blockers (bisoprolol, atenolol, metoprolol, etc.), antiplatelet agents (aspirin, aspirin Cardio, aspicor, thrombo Ass, etc.), ACE inhibitors ( enalapril, perindopril, quadripril, etc.) ndi ma statins. Kafukufuku wambiri wachitika omwe amatsimikizira kuti kugwiritsa ntchito mankhwalawa mophatikiza ndi kwabwino. Komanso, kuphatikiza kwa, mwachitsanzo, pravastatin ndi aspirin piritsi limodzi, chiopsezo chotenga myocardial infarction (7.6%) chimachepetsedwa kwambiri poyerekeza ndi kumwa mankhwala okha (pafupifupi 9% ndi 11% mukamamwa pravastatin ndi aspirin, motsatana).

Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.

Chifukwa chake, ngati ma statin adayikidwa usiku pamaso, ndiye kuti, panthawi yokhapokha kuti asamwe mankhwalawa, gulu lachipatala padziko lonse lapansi pano likumaliza kuti kumwa mankhwala ophatikizidwa piritsi limodzi ndikwabwino. Mwa zophatikiza izi, mankhwala omwe amatchedwa polypill pano akuyesedwa, koma ntchito yawo yochulukirapo idakali ochepa. Mankhwala omwe agwiritsidwa kale ntchito mosakaniza ndi atorvastatin ndi amlodipine - caduet, duplexor.

Ndi cholesterol yochuluka kwambiri (yoposa 7.4 mmol / l), kugwiritsa ntchito ma statin osakanikirana ndi mankhwala ndikotheka kuti kuichepetse kuchokera ku gulu lina - fibrate. Kusankhidwa kumeneku kuyenera kuchitidwa ndi dokotala, kuwunika mosamala kuopsa kwa zotsatirapo zake.

Simungathe kuphatikiza kutenga ma statins ndi madzi a mphesa, chifukwa zimakhala ndi zinthu zomwe zimachepetsa kagayidwe kazomwe zimapanga thupi ndikuwonjezera kuchuluka kwake m'magazi, omwe amadzala ndi kukula kwa poyipa wamavuto.

Komanso, musamamwe mankhwalawa ndi mowa, maantibayotiki, makamaka ufafanuzi wa hemithromycin ndi erythromycin, chifukwa izi zimatha kuyambitsa chiwindi. Maantibayotiki ena ophatikizidwa ndi mankhwala ochepetsa cholesterol ndi otetezeka. Kuti muwone ntchito ya chiwindi, ndikofunikira kuyesa magazi a biochemical miyezi itatu iliyonse ndikuwona kuchuluka kwa ma enzymes a chiwindi (AlAT, AsAT).

Zowopsa ndi Zabwino - Zabwino ndi Zabwino

Mukamamwa mankhwala omwe dokotala wamupatsa, wodwala aliyense amalingalira za momwe mankhwalawo alondola.Kutenga ma statins kulinso chimodzimodzi, makamaka chifukwa nthawi zambiri mumatha kumva za kuwopsa kwa mankhwalawa. Malingaliro awa amatha kusintha, chifukwa m'zaka zaposachedwa mankhwala aposachedwa amapangidwa omwe amapindulitsa kwambiri kuposa kuvulaza.

Ubwino wotenga ma statins

1. Kuchepetsa 40% yaimfa yamtima m'zaka zisanu zoyambirira,
2. 30% Kuchepetsa chiopsezo cha matenda a sitiroko ndi mtima,
3. Kuchita bwino - kutsitsa cholesterol ndikugwiritsidwa ntchito mosalekeza ndi 45 - 55% ya oyamba kwambiri. Kuti muwone kuyendetsa bwino, wodwalayo amayenera kuwezetsa magazi mwezi uliwonse chifukwa cha cholesterol,
4. Chitetezo - kutenga mbadwo waposachedwa wa ma statins mu mankhwala othandizira alibe mphamvu yakuopsa m'thupi la wodwalayo, ndipo chiopsezo cha zotsatirapo chake ndichotsika kwambiri. Kafukufuku angapo omwe achita kuwunikira kwakanthawi kwa odwala omwe akhala akutenga ma statins kwa nthawi yayitali akuwonetsa kuti kugwiritsa ntchito kwawo kungapangitse kukulira kwa mtundu wa 2 matenda a shuga, khansa ya chiwindi, matenda amkati, komanso kuwonongeka kwa malingaliro. Komabe, izi zatsimikiziridwa ndikuwonetsa kuti matendawa amatenga chifukwa cha zina. Kuphatikiza apo, ku Spain kwa odwala omwe ali ndi mtundu wachiwiri wa matenda ashuga omwe alipo kale kuyambira mu 1996, awonetsa kuti chiopsezo chotenga matenda a shuga monga matenda ashuga polyneuropathy, retinopathy amachepetsa ndi 34% ndi 40%, motero.
5. Chiyerekezo chochulukirapo chomwe chimagwira ntchito imodzi m'magulu osiyanasiyana amtengo, zomwe zimathandiza kusankha mankhwala poganizira mphamvu zomwe wodwalayo ali nazo.

Zoyipa zovuta kutenga ma statins

• Mtengo wokwera wa zokonzekera zina zoyambirira (mtanda, rosucard, leskol forte). Mwamwayi, drawback iyi imachotsedwa mosavuta pakusintha mankhwala pogwiritsa ntchito zomwezo ndi analogue yotsika mtengo.

Inde, zabwino ndi mapindu osayerekezekawa ayenera kukumbukiridwa ndi wodwala yemwe akuwonetsa kuti akuvomera, ngati akukayika ngati kuli koyenera kutenga ma statins ndikuyesa mosamala zabwino ndi zoipa zake.

Mwachidule

Mndandanda wa mankhwala omwe nthawi zambiri amaperekedwa kwa odwala amaperekedwa patebulo:

Dzina la mankhwalawa, zomwe zimapezeka mu mankhwala (mg)

Mtengo woyerekeza, rub

Ine m'badwo SimvastatinVasilip (10, 20 kapena 40)Slovenia355 — 533 Simgal (10, 20 kapena 40)Czech Republic, Israel311 — 611 Simvakard (10, 20, 40)Czech Republic262 — 402 Simlo (10, 20, 40)India256 — 348 Simvastatin (10, 20 kapena 40)Serbia, Russia72 — 177 PravastatinLipostat (10, 20)Russia, USA, Italy143 — 198 LovastatinHolletar (20)Slovenia323 Cardiostatin (20, 40)Russia244 — 368 M'badwo wachiwiri FluvastatinLeskol Forte (80)Switzerland, Spain2315 M'badwo wa III AtorvastatinLiptonorm (20)India, Russia344 Liprimar (10, 20, 40, 80)Germany, USA, Ireland727 — 1160 Torvacard (10, 40)Czech Republic316 — 536 Atoris (10, 20, 30, 40)Slovenia, Russia318 — 541 Tulip (10, 20, 40)Slovenia, Sweden223 — 549 M'badwo wa IV RosuvastatinCrestor (5, 10, 20, 40)Russia, Great Britain, Germany1134 – 1600 Rosucard (10, 20, 40)Czech Republic1200 — 1600 Rosulip (10, 20)Hungary629 – 913 Tevastor (5, 10, 20)Israeli383 – 679 PitavastatinLivazo (1, 2, 4 mg)Italy2350

Ngakhale kufalikira kotereku pamitengo yama statins, ma analogi otsika mtengo samakhala otsika kwambiri pamankhwala okwera mtengo. Chifukwa chake, ngati wodwalayo sangathe kugula mankhwalawo, ndikotheka kusintha m'malo mwake monga momwe adanenera adotolo ndi omwe ali ndi ndalama zambiri.

Kodi ndingachepetse cholesterol yanga popanda mapiritsi?

Mankhwala a atherosulinosis monga mawonekedwe a cholesterol yoipa “yambiri” m'thupi, mankhwala oyamba ayenera kukhala olimbikitsa kusintha kwa moyo, chifukwa ngati cholesterol mulibe kwambiri (5.0 - 6.5 mmol / l), ndipo chiopsezo cha zovuta zamtima ndi chochepa kwambiri, mutha kuyesa sinthani izi mothandizidwa ndi izi:

• Zakudya zoyenera, bungwe la regimen la chakudya kupatula mafuta, okazinga zakudya.Zokonda zimaperekedwa muzakudya zampweya, zophika, zopatsa mphamvu. Zakumwa za mazira (yolks), nyama yamitundu yamafuta, offal (chiwindi ndi impso), zinthu zamkaka ndizochepa. Ndikofunikira kuti musatengeko zinthu izi, koma muzigwiritsa ntchito moyenera mogwirizana ndi mfundo za chakudya choyenera, chifukwa thupi limafunikira cholesterol ngati chida chomanga bongo, chiwindi, maselo amwazi ndi ziwalo zina. Chifukwa chake, musamadye zakudya zomwe zili ndi zonse.
• Zochita zolimbitsa thupi zoyenera mkhalidwe wamtima wamatsenga (kuyenda, masewera olimbitsa thupi, zochitika mu mpweya wabwino, ndi zina zambiri).
• Kukana zizolowezi zoipa, asayansi atsimikizira kuti kumwa mowa mwauchidakwa komanso kusuta fodya kumawonjezera cholesterol yamagazi.

Zakudya zina zimakhala ndi zotchedwa zachilengedwe. Mwa zinthu izi, adyo ndi turmeric ndizophunziridwa kwambiri. Kukonzekera kwa mafuta a nsomba kumakhala ndi omega 3 mafuta acids, omwe amathandizira kagayidwe ka cholesterol m'thupi. Mutha kumwa mafuta a nsomba omwe amagulidwa ku malo ogulitsa mankhwala, kapena mutha kuphika mbale zam'madzi (trout, nsomba, nsomba, etc.) kangapo pa sabata. Mitengo yokwanira ya masamba, yomwe imapezeka muma maapulo, kaloti, phala (oatmeal, barele) ndi nyemba, ndilolandiridwa.

Pokhapokha pakuchitika njira zosagwiritsa ntchito mankhwala osokoneza bongo, adokotala amatulutsa imodzi mwazomwe zimachepetsa mankhwala a lipid.

Pomaliza, ndikufuna kudziwa kuti, ngakhale ali ndi mantha a odwala komanso lingaliro la zoopsa za ma statins, cholinga chawo ndicholondola pakufikira kwa atherosclerosis ndi kuwonongeka kwamitsempha yama coronary, popeza mankhwalawa amatalikitsa moyo. Ngati muli ndi cholesterol yayikulu popanda chizindikiro choyambirira cha kuwonongeka kwa mtima, ndiye kuti muyenera kudya moyenera, kusunthika, kukhala ndi moyo wathanzi, kenako mudzaganiza kuti mutenge ma protein.

Mapiritsi otsitsa cholesterol yamagazi ndikutsuka mitsempha yamagazi

Anthu ambiri ali ndi mavuto azaumoyo omwe amakhudzana ndi misempha. Chifukwa chake, muyenera kudziwa zomwe mapiritsi a cholesterol alipo komanso momwe amagwirira ntchito.

Anthu akapeza cholesterol yayikulu m'magazi awo, anthu ambiri amafunsa kuti: "Kodi mapiritsi a cholesterol ndi othandiza kapena ayi?" Kumwa mankhwala omwe dokotala am'patsa amathandizira kubwezeretsa m'mitsempha, m'mitsempha, ndi m'mitsempha, ndikuchotsa cholesterol plaque. Pamodzi ndi mapiritsi, kudya komanso kuchita masewera olimbitsa thupi ndizofunikira. Chifukwa chake, ndikofunikira kudziwa kuti ndi mankhwala ati omwe amachepetsa cholesterol? Kodi ayenera kumwedwa bwanji?

Cholesterol yoyipa

Chofunikira mu magazi a munthu ndi cholesterol, yomwe imapezeka pafupifupi ziwalo zonse. Vitamini D ndi ma enzymes a mahomoni amapangidwa kuchokera pamenepo, ndipo amakhalanso chitetezo chokwanira. Cholesterol imathandizira kuti ubongo uzigwira bwino ntchito, chiwindi, minofu ndi minyewa. Komabe, kuchokera ku cholesterol yayikulu, ma pathologies owopsa a mtima amatuluka.

Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.

• imalepheretsa kuchulukana kwa ma hydrocarbons,
• kutenga nawo mbali popanga maselo am'mimba,
• imathandizira mapangidwe a bile ndi mahomoni opangidwa ndi ma adrenal glands,
• nawo kagayidwe,
• imasiyanitsa zingwe zam'mitsempha
• amathandiza kuyamwa vitamini D.

Enzyme imapangidwa ndi maselo a chiwindi, ndipo mapuloteni amasintha kudzera mu plasma. Zotsatira zake, maunyolo mawonekedwe, omwe pambuyo pake amasintha kukhala zigawo za lipoprotein zosiyanasiyana.

Zokhudza thupi zimatengera kapangidwe kazinthu izi. Ngati lipoproteins yotsika kwambiri (LDL) ilipo, ndiye kuti mafupa amapezeka m'matumba, pambuyo pake atherosulinosis.Ndi mkulu impermeability (HDL), kusinthana kolondola kwa cholesterol ndi asidi acids kumachitika, zomwe zimapangitsa kuti achepetse vuto la atherosulinosis.

Kuti mudziwe kuchuluka kwa chinthuchi, kuyezetsa magazi kwamomwe amachitika. Zizindikiro za miyambo zimasiyana pakati pa abambo ndi amai, zaka za munthu zimakhudzanso mtengo. Mu theka lolimba, cholesterol yokwezeka imawonedwa nthawi zambiri.

Kuwonjezeka kwa kuchuluka kwa osachulukitsa lipoproteins patatha zaka makumi asanu kumadziwika. Mwa akazi, chodabwitsachi chimamveka pa nthawi ya kusamba.

Zotsatira zake, njira zazikulu za pathological monga kusokonezeka kwa magazi muubongo zimatha kuchitika, zomwe nthawi zambiri zimayambitsa kuphwanya pansi kwa myocardial. Chifukwa chake, madokotala amapereka mankhwala othandizira kutsitsa cholesterol.

Ndi vuto la mtima kapena stroko, simungalole cholesterol kutukuka. Popeza kuyambiranso kwa chitukuko cha ma pathologies obwereza kungachuluke.

Ngakhale kuti cholesterol yapamwamba ndiyowopsa. Udindo wake pakachulidwe kakakulu, umatenga mbali pazinthu zonse zamitundu mitundu ndipo umafunika pa moyo wa thupi. Chifukwa chake, kuisunga kuti ikhale yachilendo ndikofunika, chifukwa amagwiritsa ntchito mankhwala ndikukhala ndi njira yolondola.

Chizindikiro chatsika

Zakudya Zabwino zimasankhidwa ndi adotolo, koma zimatengera:

• kusiya mowa, kusuta,
• Kuchepetsa mchere komanso zakudya zamafuta,

• Kuletsedwa kwamafuta am nyama, ndikwabwino kudya mafuta azamasamba,
• CHIKWANGWANI chamasamba, zophatikiza mafuta ndi ma polyunsaturated acid ziyenera kupezeka m'zakudya.

M'pofunika kusiyiratu masoseji ndi masoseji, makeke, makeke, masikono ndi ma muffin. Zakudya zopatsa thanzi sizingathandize kuchotsetsa kwambiri, komanso kukonza thanzi la munthu.

Ndikofunika kudziwa kuti 80% ya cholesterol imapangidwa m'chiwindi, ndipo 20% yotsala imapanga zakudya zomwe zimamwa. Chifukwa chake, kudya moyenera komanso moyenera kumathandizanso kuti matenda abwinidwe.

• kuwonda
• zolimbitsa thupi tsiku lililonse
• samalani kalori

• kusiya zizolowezi zoipa: mowa, kusuta,
• Pewani kupsinjika ndi mantha amanjenje.

Kuti muchepetse izi, mutha kugwiritsa ntchito zinthu potengera mankhwala azitsamba ndi zina zowonjezera pazamoyo. Mafuta ochulukirapo a Omega-3 polyunsaturated amalepheretsa kukula kwa magazi ndikukula kwa magazi kuti apange.

Pali nthawi zina pamene kutsatira zakudya, kusiya mowa ndikuchita masewera olimbitsa thupi kwa nthawi yayitali sikuthandizira kuchepa kwa cholesterol. Kenako dokotala amalimbikitsa kumwa mankhwala apadera kuti muchepetse cholesterol.

Mbiri yachitukuko

p, blockquote 3,0,0,0,0,0,0 ->

Mankhwala akhala akufunafuna mankhwala omwe amachepetsa cholesterol kwa nthawi yayitali (kuyambira 1962). Ngakhale pamenepo zidadziwika kuti ndiomwe adayambitsa matenda a mtima komanso matenda a mtima. Chiwerengero chachikulu cha ma labotale, zaka zambiri zogwira ntchito, ndalama zambiri - kwa zaka makumi ambiri zonsezi sizinabweretse zotsatira. Panali mavuto awiri. Poyamba, amawopa kuti mankhwalawa atha kukhala ndi zotsatila zambiri, chifukwa ma lipoproteins ndi omwe amapanga ma membrane am' cell ndipo amatenga nawo gawo popanga ma bile acid ndi ma steroid achule. Ngati mungaletse kaphatikizidwe kake, njira zonsezi zidzasokonekera. Kachiwiri, zoyesa pa makoswe sizinapereke zotsatira, ziribe kanthu momwe adayesera.

p, blockquote 4,0,0,0,0,0,0 ->

Ngakhale mavutowa, wasayansi wa ku Japan, a Endo Akira, adapitilizabe kufunafuna mankhwala omwe apulumutse anthu ku cholesterol plaque, atherosclerosis, ndi matenda ena amtima. Kafukufuku wake adachitika kuyambira 1971 mpaka 1976. Maphunziro a 6,000 ndi zaka 5 - nthawi yayitali kwambiri zidatenga timu yake kuti ipange statin yoyamba.

p, blockquote 5,0,0,0,0 ->

Dokotala waluso adalimbana mwachangu ndi chopunthwitsa chachiwiri: zidapezeka kuti cholesterol ndiyofala komanso yovulaza.Othandizirawa adachepetsa kapangidwe kachiwiri, koma thupi lanyama lidalipira chifukwa chosowa, ndikuwonjezera yoyamba, yomwe idayang'aniridwa panthawi ya ntchito. Izi zitapezeka, zidapezeka kuti mankhwalawo amagwiradi ntchito ndipo amathandizadi.

p, blockquote 6.0,0,0,0,0 ->

Mankhwala oyamba a statin anali Kompaktin, yemwe amayenera kupirira ambiri. Ngakhale idagwira, idadziwika kuti ndi yodula ndipo imaletsa kupanga. Komabe, nthawi yama statins inali yotseguka kale, ndipo anthu sakanatha kuwasiya. Kuyambira 80s ya XX century, abweretsa ndalama zabwino kumakampani opanga mankhwala.

p, blockquote 7,0,0,0,0 ->

Komabe, vuto loyamba lomwe lidayambika pakukula kwa mankhwala a cholesterol likadali lothandiza mpaka pano. Ma Statist ali ndi zotsatira zoyipa. Chifukwa chake, m'zaka khumi zapitazi, ntchito zina zopatsanso lipid zotsika zikuchitika.

p, blockquote 8,0,0,0,0 ->

Zambiri

Ngati cholesterol yokwezeka yapezeka panthawi yoyezetsa komanso kuyesa magazi, dokotalayo amapereka mankhwala omwe amachepetsa. Ndipo nthawi zambiri awa ndi ma statins. Mankhwala otsalira a lipid omwe ali ndi zotsatira zosiyana zamankhwala, opangidwa m'zaka zaposachedwa, ali ndi zovuta zochepa. Koma machitidwe awo samasunga madzi. Pambuyo pa chithandizo, adangoona kusintha komweko mwa odwala. Chifukwa chake, madokotala omwe akufuna kuwona zoyesayesa ndi kupita patsogolo amakhalabe okhulupilika ku tri-hydroxy-tri-methylglutaryl-CoA reductase inhibitors (dzina lasayansi la statins).

p, blockquote 9,0,0,0,0 ->

Popereka mankhwala omwe amachepetsa cholesterol kwa odwala awo, madokotala amakakamizidwa kuwachenjeza pasadakhale za mfundo izi:

p, blockquote 10,0,0,0,0 ->

• pofuna kuchepetsa cholesterol yoyipa, ma statins nthawi zina amayenera kukhala oledzera mosalekeza, ndiye kuti, moyo wonse,
• Palibe zopatuka malinga ndi malangizo omwe amagwiritsidwa ntchito
• zoyipa sizokhala zambiri - pakati pawo pali zina zomwe zimakhudza bwino thanzi komanso kuchepetsa moyo.

Chifukwa chake, ngakhale atakulembetsani udokotala, mutawerenga mndandanda wazotsatira zoyipa, wodwala yekha ndi amene amasankha kuti amwe ma statin. Zaka zingapo zapitazo kunalibe chosankha, popeza anali okhawo omwe anali ndi mankhwala ochepetsa lipid. Koma kuchuluka komweko kwa mankhwalawa kumapereka njira zina: ma fiber, ma lipid modifiers, othandizira, ma lipid metabolism okonza, etc. Zonsezi ndi mankhwala omwe amachepetsa cholesterol ndikuyeretsa ziwiya kuchokera ku ma atherosclerotic plaques ndi lipids zovulaza. Komabe, potengera momwe amagwirira ntchito, amakhala otsika kwambiri ma statins, omwe mpaka pano, ngakhale atatsutsidwa kangapo, amakhalabe atsogoleri polimbana ndi otsika kwambiri a lipoproteins (LDL).

p, blockquote 11,0,0,0,0 ->

Gulu la ATS

Ponena za kapangidwe ka mankhwala omwe amatha kutsitsa cholesterol, pafupifupi onsewo amapangidwa. Zithandizo za zitsamba zimaphatikizapo Lovastatin (bowa wa oyster), Polyconazole (nzimbe zamchere), Guarem (nyemba za hyacinth) ndi zina zowonjezera zakudya, nthawi zina zomwe zimaperekedwa kuti zimayamwa mapiritsi a atherosranceotic, koma sizigwira ntchito pakumwa mankhwala otsitsa a lipid.

p, blockquote 13,0,0,0,0 ->

Kutulutsa Fomu

Malinga ndi mawonekedwe a kumasulidwa, mankhwala ambiri amapangidwa ngati mapiritsi kapena makapisozi. Ena ali ngati madzi osungunuka a madzi. Mwanjira ya jakisoni, mankhwala a nicotinic acid ndi mankhwala atsopano a ku America a Repatha (Repat) ndi Praluent (Kutchuka) ndi omwe adayikidwa, omwe akadagonjetsanso msika wogulitsa mankhwala.

p, blockquote 14,0,0,0,0 ->

Dzina lovomerezeka: tri-hydroxy-tri-methylglutaryl-CoA reductase inhibitors.

p, blockquote 15,0,0,0,0 ->

Khodi ya PBX: C10AA.

p, blockquote 16,0,0,0,0 ->

Gome limapereka mndandanda wazinthu zazikulu zomwe zimagwira ntchito zama statins ndi mankhwala omwe amapangidwa pamaziko awo, zomwe zimawonetsa kugwira ntchito kwawo (mwa kuchuluka komwe amatha kutsitsa cholesterol yamagazi):

p, blockquote 17,0,0,0,0,0,0 ->

p, blockquote 18,0,0,0,0 ->

p, blockquote 19,0,0,0,0 ->

• Ine: Lovastatin, Simvastatin, Pravastatin,
• II: fluvastatin,
• III: Atorvastatin, Cerivastatin,
• IV: Pitavastatin, rosuvastatin.

Ntchito ya m'badwo uliwonse wotsatira wa mankhwala ndikuwonjezera mphamvu yawo ndikuchepetsa chiopsezo cha zotsatila ndi zotsutsana. Monga momwe zimakhalira pakuyesedwa kuchipatala, izi sizinathandize ma statins. Makampani otukula sanakwaniritse izi. Ndipo ngakhale njira yachinayi, m'badwo wotsiriza udakali woopsa potengera zovuta zaumoyo.

p, blockquote 20,0,0,0,0 ->

p, blockquote 21,0,0,0,0 ->

• mwachangu komanso moyenera kuchepetsa cholesterol yamagazi ndi 60%, popeza amaletsa ntchito yama enzymes (HMG-CoA reductase), yomwe imathandizira kupanga lipoproteins zovulaza,
• onjezani kuchuluka kwa cholesterol yopindulitsa,
• Sinthani kapangidwe ka minofu yamtima, kupewa kufooka kwake,
• muloleni azigwira bwino ntchito,
• lekani nkhawa
• kuchepetsa chiopsezo cha ischemia ndi 15%, angina pectoris ndi vuto la mtima - mwa 25%,
• onjezerani chiyembekezo chamoyo.

p, blockquote 22,0,0,0,0 ->

• ochepa matenda oopsa
• atherosulinosis
• hypercholesterolemia,
• myocardial infaration
• Matenda a mtima wa Ischemic,
• ACS
• kupewa stroke, kugunda kwamtima,
• opaleshoni ya mtima ndi yamtima.

p, blockquote 23,0,0,0,0 ->

Komabe, monga momwe masewera amasonyezera, ndikofunikira kupatsa ma statins motsutsana ndi atherosulinosis ndi CVD ena okha kwa anthu azaka zapakati. Kwa okalamba (atatha zaka 60-70), ndiwosathandiza ndipo amawononga kuposa thandizo.

p, blockquote 24,0,1,0,0 ->

Otsatira a bile acid

Khodi ya PBX: C10AC.

p, blockquote 43,0,0,0,0 ->

p, blockquote 44,0,0,0,0 ->

• Colextran (Questran),
• Kwa Kolesevelam (Colesevelam),
• Cholestipol, Colestipol (Colestipol),
• Cholestyramine, Colestyramin (Colestyramin).

Ali ndi mphamvu yamankhwala. Pangani zolimba zamankhwala olimba ndi bile acid ndikuwachotsa. Thupi limakumana ndi kuperewera kwakukulu kwa zinthu zomwe ndizothandiza kwambiri pantchito zake zofunika. Chizindikiro chofananira chimatumizidwa ku chiwindi, chomwe chimayamba kaphatikizidwe kake kosagwira. Kuti achite izi, amafunika mafuta ambiri a cholesterol, omwe amawononga. Chifukwa chake kuchuluka kwake m'magazi kumachepa.

p, blockquote 45,0,0,0,0 -> Otsatira a bile acid

Nthawi zambiri amapezeka mu mawonekedwe a ufa sungunuka m'madzi kapena madzi.

p, blockquote 46,0,0,0,0 ->

Samayamwa magazi, chifukwa chake amakhala otetezeka ku thanzi. Komabe, madotolo ambiri amatsutsana nawo chifukwa amachepetsa kuchuluka kwa ma asidi a bile, ofunikira pakugwira ntchito kwamankhwala ambiri ndi machitidwe. Chiwindi sichikhala ndi nthawi yopanga kuchuluka kwake kofunikira. Amachepetsa kuyamwa kwa folic acid m'matumbo.

p, blockquote 47,0,0,0,0 ->

Tiyenera kukumbukira kuti mulingo wa triglycerides wogwiritsa ntchito bile acid amachepetsa. Makamaka pa izi, muyenera kumwa mitundu ina ya mankhwala motsatana.

p, blockquote 48,0,0,0,0 ->

Kukonzekera kochokera ku Niacin

Khodi ya PBX: C10AD.

p, blockquote 49,1,0,0,0 ->

p, blockquote 50,0,0,0,0 ->

• Acipimox (Acipimox),
• Aluminium nikotini (Aluminium chikonga),
• Niacin (Ac>Niacin

p, blockquote 51,0,0,0,0 ->

• kuchepetsa cholesterol yoyipa ndikuwonjezera zabwino
• yambitsani fibrinolysis,
• kuchepetsa thrombosis.

Mankhwalawa ndiwotalikirapo, ndikuwonjezera pang'onopang'ono. Ma Statin ndi ma fiber amaphatikizidwa kuti agwiritse ntchito nthawi imodzi ndi mankhwala okhala ndi chikonga (kuphatikiza kwawo kumayambitsa chitukuko cha zotsatira zoyipa).

p, blockquote 52,0,0,0,0 ->

p, blockquote 53,0,0,0,0 ->

• matenda ashuga
• gout
• gastritis
• zilonda zam'mimba.

Ola limodzi lisanathe ndi ola limodzi mutatha kukonzekera ndiacac acid, simungathe kumwa zakumwa zotentha. Zotsatira zoyipa, pamimba pamakhala kusokonezeka, koma nthawi zambiri izi zimachitika pamaso pa khungu kapena zilonda zam'mimba. Mukangogwiritsa ntchito, matenda oopsa a nkhope amayamba. Kupatula izi, spirin imatengedwa theka la ola musanatenge. Ena amazindikira zovuta zam'makutu: kuyabwa kwa khungu, mawonekedwe a zilonda zam'mimba.

p, blockquote 54,0,0,0,0 ->

Mankhwala ena otsitsa lipid

Khodi ya PBX: C10AX.

p, blockquote 55,0,0,0,0 ->

Ezetimibum (Ezetimibum)

p, blockquote 56,0,0,0,0 ->

p, blockquote 57,0,0,0,0 ->

Mayina amalonda: Ezetrol, Ezetimibe, Lipobon, Otrio. Mankhwala ndi m'badwo watsopano. Machitidwe ake a pharmacological amasiyana ndi malingaliro a ntchito ya mankhwala ena otsitsa a lipid.Amadziunjikira m'matumbo ang'onoang'ono ndipo amalepheretsa mayamwidwe a cholesterol. Izi zimabweretsa kuchepa kwa kudya kwake m'chiwindi. Chifukwa chake ma lipoproteins amachepetsedwa, ndipo kuchotsedwa kwawo kwa magazi kumawonjezereka.

p, blockquote 58,0,0,0,0 ->

Hypersensitivity, chiwindi chachikulu, kuyamwa, mimba.

p, blockquote 59,0,0,0,0 ->

Zotsatira zoyipa: kutsekula m'mimba, kutopa, chimfine, sinusitis, matenda apumidwe am'mimba thirakiti, arthralgia, kupweteka kwa minofu. Sikulimbikitsidwa kuphatikiza ndi cyclosporine ndi mankhwala ena ochepetsa a lipid.

p, blockquote 60,0,0,0,0 ->

Policosanol (Policosanol)

p, blockquote 61,0,0,0,0 ->

p, blockquote 62,0,0,0,0 ->

Mafuta a cholesterol am'badwo wotsiriza. Pambuyo pa mayeso azachipatala, adawonetsa kugwira ntchito kwambiri ngakhale poyerekeza ndi ma statins. Nthawi yomweyo, mavuto amawonedwa nthawi zambiri, ndipo si owopsa ku thanzi. Munjira, amachepetsa kuchuluka kwa alanine aminotransferase ndi gamma glutamyl transpeptidase. Amapangidwa pamaziko a aliphatic alcohols ochokera ku nzimbe.

p, blockquote 63,0,0,0,0 ->

Zofika zaka 18, pakati, Hypersensitivity, mkaka wa m'mawere.

p, blockquote 64,0,0,0,0 ->

Zotsatira zoyipa: nseru, kutsegula m'mimba.

p, blockquote 65,0,0,0,0 ->

Primphol

p, blockquote 66,0,0,0,0 ->

p, blockquote 67,0,0,0,0 ->

Mayina amalonda: Bifenabid, Fenbutol, Lesterol, Lipomal, Superlipid. Imagwira kawiri: imachepetsa kapangidwe ka cholesterol mu chiwindi ndi mayamwidwe ake m'magazi kuchokera m'matumbo. Zilibe kukhudzana ndende ya triglycerides. Tumizani ndi hypercholesterolemia, kuwonongeka kwa ziwiya zama coronary. Contricia arrhythmias, mimba, kuyamwa. Zotsatira zoyipa, dyspepsia imadziwika kwambiri. Chosavuta cha Studucol ndikuti amachepetsa mafuta amafuta oyipa komanso opindulitsa. Ambiri samakondanso kufunikira kwa chithandizo chautali. Zotsatira zoyambirira zimawonekera pokhapokha miyezi iwiri atayamba kugwiritsa ntchito. Tiyenera kukumbukira kuti chida ichi chikhoza kupotoza zotsatira za electrocardiogram.

p, blockquote 68,0,0,0,0 ->

Omega 3 Polyunsaturated Fatty Acids

p, blockquote 69,0,0,0,0 -> Zowonjezera zamafuta a Omega-3 polyunsaturated fat acids

Mayina amalonda ogulitsa zakudya: Doppelgerz Omega, Omacor, Oceanol. Nthawi zambiri mumakhala mafuta a nsomba. Amachepetsa chiopsezo cha CVD, amachepetsa cholesterol, amakupulumutsani ku kukhumudwa, ndikuchotsa matenda a nyamakazi. Kugwiritsa ntchito molakwika kapena nthawi yayitali, zimatha kupangitsa kuti kapamba azisamba.

p, blockquote 70,0,0,0,0 ->

Dextrotyroxine (Dextrothyroxine)

p, blockquote 71,0,0,0,0 ->

Amadziwika ndi mayamwidwe abwino a m'matumbo. Amayika ngati pakufunika kuchepetsa transcendental ndende ya cholesterol. Munjira, zimathandiza kutulutsa chithokomiro. Imalimbitsa katundu wake wa hypolipidemic kuphatikiza ndi chikonga ndi clofibrate. Chithandizo chimayikidwa ndi milingo yochepa kwambiri yotsatiridwa ndi kuchuluka kwawo. Zotsatira zoyipa: kulekerera kwa chakudya chamthupi kumachepa, kuwonjezereka kwa bilirubin, leukopenia imapezeka.

p, blockquote 72,0,0,0,0 ->

Kulephera kwa mtima, kwambiri angina pectoris, matenda a shuga.

p, blockquote 73,0,0,1,0 -> mankhwala opangira jekeseni aku America Repatha (Repat) and Praluent (Praful)

Mankhwala ochepetsa lipid osonyezedwa pansi pa code C10AX mu ATS mulinso:

p, blockquote 74,0,0,0,0 ->

• Benfluorex (Benfluorex) - yoletsedwa m'maiko angapo chifukwa cha kuwopsa kwake,
• Magnesium pyridoxal, coenzyme B6 (Magnesium pyridoxal 5-phosphate glutamate),
• Meglutol (Miglutol),
• Thiadenol (Tiadenol).

Mankhwala obayira a ku America Repatha (Repat) ndi Praluent (Praful) alonjeza kuti achulukitsa kuchuluka kwa cholesterol m'mankhwala 2 okha pa sabata. Komabe, achipatala safulumira kuwalimbikitsa iwo kwa odwala ake, popeza akadali mayeso ambiri azachipatala kuti atsimikizire kugwira kwawo ntchito.

p, blockquote 75,0,0,0,0 ->

Zophatikizika za Lipid

p, blockquote 76,0,0,0,0 ->

Mndandanda wazosakanikirana zotchuka ndi zotchuka:

p, blockquote 77,0,0,0,0 ->

• Atorvastatin + Amlodipine,
• Lovastatin + Nicotine,
• Pravastatin + Aspirin,
• Simvastatin + Asipirin,
• Simvastatin + Ezetimibe.

Kuphatikiza komweku kwa mankhwala kumapangidwira kuti apititse patsogolo kutsitsa kwa lipid.

p, blockquote 78,0,0,0,0 ->

Si aliyense amene ali ndi chidwi chofuna kutsitsa cholesterol ndi mankhwala amphamvu opangira. Chifukwa chake, ngati zomwe zili sizikukwera kwambiri, dokotala atha kukuwonjezera zowonjezera zachilengedwe zokhala ndi lipid-kuchepetsa. Amachita modekha komanso amakhala ndi mawonekedwe achilengedwe. Komabe, posankha kugwiritsa ntchito, muyenera kuzindikira kuti si mankhwala ndipo sangathe kuthana ndi matenda oyipa omwe amakhudzana ndi lipoproteins. Amatha kusintha pang'ono pokha.

p, blockquote 79,0,0,0,0 ->

Chofunika Forte N

p, blockquote 80,0,0,0,0 ->

p, blockquote 81,0,0,0,0 ->

Mankhwala osakanikirana a hepatoprotective, omwe amaphatikizira phospholipids "ofunika" (cholinophosphoric, linoleic ndi linolenic acid), pyridoxine, cyanocobalamin, nikotini, pantothene, riboflavin, tocopherol. Chimalimbikitsa kusokonekera ndikuchotsa "cholesterol" yoyipa ", imalimbikitsa zinthu zabwino" zabwino ".

p, blockquote 82,0,0,0,0 ->

Tykveol

p, blockquote 83,0,0,0,0 ->

p, blockquote 84,0,0,0,0 ->

Muli mafuta a nthanga. Amasonyezedwa mankhwalawa cholecystitis, atherosulinosis, hepatitis. Ili ndi hepatoprotective, antioxidant, anti-yotupa ndi choleretic katundu.

p, blockquote 85,0,0,0,0 ->

Guarem

p, blockquote 86,0,0,0,0 ->

p, blockquote 87,0,0,0,0 ->

Kukonzekera azitsamba. Amachotsa cholesterol pomwe ali m'matumbo, kuchepetsa kuyamwa kwake m'magazi. Nthawi yomweyo, imathandizira kupukusira kwa ma asidi a bile, ndikupangitsa chiwindi kuti chiwapangitse kwambiri. Imapondera kudya, kuthandiza kuonda. Amapezeka mu ma granules omwe amasungunuka m'madzi, madzi kapena mkaka. Zimaphatikizidwa bwino ndi mankhwala ena otsitsa a lipid. Zotsatira zoyipa: kuchulukana kwa msana, mseru, kusasangalala ndi m'mimba, kutsekula m'mimba.

p, blockquote 88,0,0,0,0 ->

Lipoic acid

p, blockquote 89,0,0,0,0 ->

p, blockquote 90,0,0,0,0 ->

Ndi antioxidant wamkati. Amayikidwa pa matenda a coronary atherosulinosis.

p, blockquote 91,0,0,0,0 ->

SissPren

p, blockquote 92,0,0,0,0,0 ->

p, blockquote 93,0,0,0,0 ->

Amapangidwa pamaziko a fir Tingafinye. Ndi thandizo mankhwalawa ochepa matenda oopsa, atherosulinosis. Ochepetsa triglycerides ndi cholesterol yoyipa.

p, blockquote 94,0,0,0,0 ->

Mavitamini

p, blockquote 95,0,0,0,0 ->

Mavitamini a gulu B amathandiza kutsitsa cholesterol: riboflavin (B2), pyridoxine (B6), folic acid (B9) ndi cobalamin (B12). Mphamvu ya kutsitsa kwa lipid ya nikotini (B3) ikufotokozedwa pamwambapa. Mankhwalawa amatha kuperekedwa palokha kapena kuphatikizana. Thandizo labwino kwambiri lingakhale vitamini Benzaflavin (yozikidwa pa riboflavin).

p, blockquote 96,0,0,0,0 ->

Mankhwala ochepetsa mphamvu ya cholesterol amayenera kuthandizidwa mosamala kwambiri chifukwa cha kuchuluka kwa mavuto omwe angayambitse. Nthawi zambiri, kugwira ntchito kwawo popewa matenda a atherosulinosis ndi ma CVD ena ndikofunikira kwambiri kuposa zotsatira za kugwiritsidwa ntchito kwawo. Kuti muchepetse zowopsa, simungathe kuzigwiritsa ntchito nokha, popanda kutsatira dokotala, ndikuphwanya malangizowo.

p, blockquote 97,0,0,0,0 -> p, blockquote 98,0,0,0,0,0 ->

Mitundu ya Mankhwala

Masiku ano, pali mankhwala ambiri omwe amagwiritsidwa ntchito pa cholesterol yapamwamba. Amapezeka ngati mapiritsi ndi makapisozi. Dokotala, poganizira momwe wodwalayo alili, amasankha njira zothandiza kwambiri ndi zochepa zoyipa.

Mankhwala omwe amagwiritsidwa ntchito pa cholesterol yayikulu m'magazi amagawidwa m'mitundu ingapo.

1. Madera
2. Fibates.
3. Mankhwala omwe amasokoneza mayamwidwe a otsika osalimba a lipoprotein.
4. Nicotinic acid

Palibe mapiritsi abwinoko a cholesterol, mumtundu uliwonse wamankhwala pali zabwino zambiri komanso zovuta.

Mabedi amawoneka kuti ndiofala kwambiri; amachepetsa mafuta m'thupi mwachangu. Zilibe kuvulaza chiwindi, ngakhale kukhala ndi phindu pa izo.Komabe, ngati munthu ali ndi matenda oopsa a chiwindi, mankhwalawa amaletsedwa kugwiritsa ntchito, chifukwa zovuta kwambiri (kulephera kwa chiwindi) zimatha kuchitika.

Mndandanda wazithunzi zotchuka:

1. Simvastatin - Zokor, Vasilip.
2. Atorvastatin - Liprimar, Atoris.
3. Rosuvastatin - Crestor, Acorta.

Amphamvu kwambiri ndi ndalama zamagulu a Atorvastatin ndi Rosuvastatin, ndikulimbikitsidwa kuti muzimwa kamodzi usiku. Zilibe zotsatira zoyipa, choncho zimatha kuperekedwa kwa ana.

Mankhwala othandizira amaonedwa ngati osagwira ntchito. Zimakhudza kagayidwe ka lipid, makamaka kuchuluka kachulukidwe lipoprotein. Mankhwalawa amayikidwa pamaphunziro. Ma fimuti saloledwa kuphatikizidwa ndi ma statins. Iwo, monga mankhwala onse, amakhala ndi zotsatirapo zoyipa, chifukwa chake akapatsidwa, mawonekedwe amunthu amakhudzidwa.

Cholesterol mayamwidwe inhibitors (IAH) sakhala otchuka kwambiri, mutha kugula mtundu umodzi wa mankhwala (Ezetrol) mu pharmacy. Kutsitsa cholesterol kumatheka mwa kuletsa kuyamwa kwa lipids pamatumbo. Mankhwalawa alibe zotsatira zoyipa, ndipo amatha kuphatikizidwa ndi ma statins.

Nicotinic acid kapena niacin imapereka zotsatira zabwino. Imalepheretsa kupanga lipids. Komabe, nicotinic acid imangokhudza mafuta acids, kotero pamapeto pamaphunzirowa, microcirculation imadziwika. Monga lamulo, ndikudya ndalama pafupipafupi, zotsatira zotsitsa zimachitika.

Komanso, pakukhazikitsa lamulo logaya chakudya, ma sequenti a bile acids ayenera kumwedwa. Zothandiza kwambiri ndi cholestyramine ndi colestipol. Zikuwoneka kuti zimapanga ma asidi a bile ndikuzitengera kunjira zoyenera. Ndikusowa kwa iwo m'thupi, cholesterol imawonjezeka. Komabe, amaikidwa kangapo, chifukwa ali ndi zovuta zambiri.

Mafuta achilengedwe a polysaturated amachulukitsa oxidation m'magazi, potero amachepetsa milingo ya lipid. Zilibe zovuta, koma zotsatira zake sizichitika nthawi yomweyo, koma patapita nthawi yayitali.

Zowonjezera zimachepetsa triglycerides mu chiwindi ndikuchepetsa LDL. Zotsatira zamankhwala ndizotalikirapo, motero zimayikidwa kuwonjezera pa mankhwala akuluakulu. Mwachitsanzo, ngati pali chakudya chochepa m'zakudya za anthu, ndiye kuti kudya zakudya zamafuta owonjezera zakudya kungapangitse izi.

Zothandiza kwambiri kutsitsa cholesterol yamagazi ndi:

1. Omega Forte.
2. Tykveol.
3. Lipoic acid.
4. Mafuta opindika.

Mukamapereka mankhwala a cholesterol, makamaka dziwani:

• jenda ndi zaka
• kukhalapo kwa matenda oyamba ndi mtima,
• zizolowezi zoipa ndi moyo wawo.

Chifukwa chake, pali mndandanda wambiri wamapiritsi a cholesterol. Ndikofunikira kusankha chithandizo choyenera, mukuganizira zonse zomwe wodwalayo ali nazo, pokhapokha, kuchepa kudzakhala kopindulitsa.

Ndi dokotala yekhayo amene angakupatseni mankhwala oyenera ndi malingaliro ena omwe amafunikira.

Popewa, madokotala amalangiza pambuyo pa zaka 20 (kawiri zaka khumi) kuti awunikenso kuti adziwe kuchuluka kwa cholesterol. Popeza ndi ukalamba mwa anthu omwe akutsogolera moyo wolakwika, umatha kuchuluka. Ngati wodwala ali pachiwopsezo, ndiye kuti chizindikirocho chiyenera kuyang'aniridwa pafupipafupi, osachepera 1-2 pachaka.

Mankhwala abwino kwambiri omwe amachepetsa mafuta m'thupi

Pali njira zingapo zolimbana ndi cholesterol yayikulu. Choyamba, kutsatira zakudya ndi njira zina, komanso kugwiritsa ntchito mankhwala omwe ali ndi vuto la hypoglycemic.

Madokotala amalimbikitsa kuti musamamwe mankhwala omwe mumamwa nokha ndikupereka ufulu wakusankha mankhwala oyenera kwa katswiri woyenera. Kugwiritsira ntchito mankhwala alionse kukonzekera kungakhale ndi zovuta zingapo zoyipa, chifukwa chake, mankhwala amwini mu nkhani iyi sayenera kupewa.

Magulu a mankhwala osokoneza bongo

Ndi njira yosakanikirana yothetsera matenda a cholesterol, adokotala, choyambirira, amapatsa wodwala zakudya zamankhwala. Gawo lachiwiri ndikupereka mankhwala. Mankhwala otsitsa cholesterol amatha kuikidwa motere:

• ma statins
• michere ya micro
• mankhwala omwe amalimbikitsa mphamvu ya choleretic,
• mankhwala azitsamba cholesterol akuchepetsa.

Odwala salimbikitsidwa kuyesa kuphatikiza mankhwalawa pawokha komanso kukana kudzipatsa mankhwala. Mukamaphatikiza mankhwala ndi maphikidwe omwe amawoneka kuti ndi wowerengeka, malingaliro a dokotala owonjezera amafunikiranso. Zotsatira zoyipa zakumwa mankhwala zimatha kuyamba pang'onopang'ono, choncho, mankhwalawa onse ayenera kumwedwa moyang'aniridwa ndi dokotala. Pakakhala kuti pali matenda aliwonse oyanjananso, timalimbikitsidwanso kudziwitsa dokotala za izi. Zonsezi zikuthandizira kupewa zovuta zina ndikuwongolera kuchiritsa kwabwino.

Kulandila kwa mankhwala amtundu uliwonse wamagulu azamankhwala kuyenera kutsagana ndi moyo wathanzi, kukana zizolowezi zoyipa ndikutsatira zolimbitsa thupi zolimbitsa thupi. Njira ina ndi chakudya. Kuchokera pachakudyacho ayenera kuchotsera ntchito yokazinga, mchere, zonunkhira. Zakumwa: msuzi watsopano ndiwololedwa. Ndikofunika kupewa kugwiritsa ntchito madzi otsekemera.

Gulu loyambirira komanso lalikulu la mankhwala: ma statins. Mankhwalawa amathandizira kupondereza mapangidwe a lipoprotein otsika kwambiri ndikuchepetsa mulingo wa triglycerides m'madzi a m'magazi. Zotsatira zoyipa zomwe zimachitika zimatha kuwonjezeka kwambiri pamankhwala omwe amapezeka komanso kuphatikiza kwa ma statin omwe ali ndi magulu ena a mankhwala. Gulu la mankhwalawa ndiwambiri kwambiri ndipo limaphatikizapo mayina opitilira 70 a malonda. Zinthu zomwe zimagwiritsidwa ntchito pokonzekera zimatha kusintha ndipo zimagawika m'mibadwo. Chofunikira kwambiri ndi zinthu zotsatirazi: atorvastatin, rosurvastatin, simvastatin, lovastatin.

Mwa zina zomwe zingachitike mutamwa mankhwala a statin, zikhalidwe izi ndizosiyanitsidwa: zovuta zam'mimba, zomwe zimatha kufotokozedwa mwanjira yofikira, kudzimbidwa, nseru, komanso, odwala angadandaule za kusokonezeka kwa kugona, chizungulire, komanso kupweteka mutu. Kupezeka kwa zotsatira zoyipa zilizonse ndi chifukwa chofunsira upangiri wa dokotala. M'tsogolomu, kusintha kwa mankhwalawa kapena kusintha kwa mankhwalawa ndi koyenera kwambiri kungafunike.

Pogwiritsa ntchito mankhwala a gululi kwa nthawi yayitali, kuwunika momwe impso ikuyendera ndikofunikira. Malinga ndi kafukufuku wosiyanasiyana, kugwiritsa ntchito ma statins nthawi zonse kumawonjezera mwayi wokhala ndi matenda ashuga.

Mankhwala otsitsa cholesterol amakhalanso ndi zotsutsana zingapo. Mwachitsanzo, samalimbikitsidwa chifukwa cha anthu omwe ali ndi vuto lalikulu la impso komanso ndi vuto lililonse lomwe limagwiritsidwa ntchito ndi mankhwalawa.

Odwala amatha kukambirana ndi dokotala zinthu zatsopano zomwe zapezeka posachedwa pamsika wamankhwala. Izi zimakuthandizani kusankha mankhwala othandiza komanso otetezeka. Mwachitsanzo, mankhwala opangidwa ndi fluvastatin ndi am'badwo waposachedwa kwambiri wama statins. Awa ndimankhwala amakono omwe ali ndi mavuto ochepa komanso othamanga. Wogulitsa zamankhwala pamankhwala angalangizenso wodwala zamankhwala atsopano, ogwira mtima. Komabe, muyenera kukumbukira kuti kuikidwa kwa mankhwala kuti muchepetse cholesterol kumangololedwa ndi adokotala, chifukwa cha wodwalayo.

Statin amalembedwa mosamala kwambiri kwa okalamba.Izi ndichifukwa choti kugwiritsa ntchito atorvastatin komweku kungapangitse kuwonjezeka kwa ululu m'dera la minofu. Komanso, odwala ambiri okalamba anazindikira kusokonezeka kwa kugona, kukhumudwa, komanso kusowa kudya.

Fibroic acid

Gulu lachiwiri lalikulu limaphatikizapo mankhwala omwe amachepetsa cholesterol yamagazi kuchokera pagulu la fibroic acid. Gulu la mankhwalawa lingagwiritsidwe ntchito ngati chowonjezera cha mankhwala a group la statin. Chizindikiro cha mankhwala a gulu la fibroic acid ndikuthekera kwawo kuchepetsa ma triglycerides ndi lipoproteins yotsika, komanso kumachulukitsa kuchuluka kwa lipoproteins yapamwamba yomwe imalimbana bwino ndi cholesterol yoyipa. Zothandiza kuchokera ku michere ya michere zimatha kumanga ku bile ndikutchingira kapangidwe ka cholesterol ndi thupi la munthu.

Akatswiri amapereka ziwonetsero zomwe zikusonyeza kuti kumwa kwa masiku 30 a group la fibroic acid amatsitsa cholesterol ndi 35-40%, triglycerides ndi 20%.

Ambiri mwa mankhwalawa amathandizidwa kudzera mu impso, chifukwa cha kusokonezeka kwa ziwalo izi, kutenga michere ya micro sikuvomerezeka. Zotsatira zoyipa zomwe zingachitike mutamwa mankhwala kuchokera ku gulu la fibroic acid zimagwirizanitsidwa makamaka ndi kuphwanya kwamtundu wamatumbo.

• Monga statins, kudzimbidwa, nseru, ndi m'mimba ndizotheka. Zonsezi zingafune chithandizo chowonjezera, chothandizira kugwiritsa ntchito mitundu ina ya mankhwala (mwachitsanzo, omeprazole, yomwe imateteza khoma lamatumbo).
• Kuphatikiza apo, zotsatira zoyipa pamtima wamtima zimadziwika - zimawonjezera chiopsezo cha venous thromboembolism.
• Kukula kwa thupi lawo siligwirizana: redness of the khungu, kuyabwa, zotupa.
• Nthawi zina, odwala amadandaula za kupweteka kwa mutu ndikuchepetsa libido.

Ngati zina mwazotsatira izi zakula, ndikulimbikitsidwa kuti odwala aleke kumwa mankhwalawa kwa kanthawi kochepa kuti apite kuchipatala.

Cholagogue ndi mankhwala

Kutsitsa cholesterol yamagazi ndi mankhwala omwe ali ndi choleretic kwambiri kumakhala ndi zowonjezera, zabwino pazachulukidwe za triglycerides ndi lowensens lipoproteins. Mfundo zoyeserera zamankhwala a choleretic ndizosavuta: amamanga cholesterol yowonjezera ndikuchotsa pang'onopang'ono m'thupi. Kukonzekera kwa gululi kuli bwino. Zotsatira zoyipa zomwe zimachitika nthawi zina, pamakhala zovuta zilizonse m'mimba ndi kupweteka m'mimba.

Pali mankhwala apadera omwe amachepetsa mayamwidwe a cholesterol mwachindunji m'matumbo am'mimba. Izi ndi monga: Xenical, Orlistat, Ezetrol. Mankhwalawa amakhala othandizira ofunika kwambiri kuti cholesterol yowonjezera ikalowe m'thupi kudzera mu chakudya. Zotsatira zoyipa mukamagwiritsa ntchito mankhwalawa ndizosasangalatsa: kukakamira pafupipafupi kufooka, komwe kumayendetsedwa ndi kutulutsidwa kwamafuta ochulukirapo, kupweteka pamimba, zimachitikira. Poyerekeza ndi momwe gulu ili limaperekera mankhwala, chakudya chofunikira ndichofunika kupatula mafuta onse okhazikika.

Njira zowonjezera

Kugwiritsa ntchito mankhwala a lipoic acid ndi makapisozi, omwe amaphatikizira zigawo za omega-3, omega-6 ndi omega-9, komanso mankhwalawa.

• Makapisozi a adyo owuma amagwiritsidwanso ntchito ngati chithandizo chowonjezera cha hypercholesterolemia.
• Othandizanso ndi mankhwalawa omwe amaphatikiza mbewu ya maungu. Mwachitsanzo, mankhwalawa Tykveol amathandiza kukhazikitsa kagayidwe ka lipid komanso amachepetsa triglycerides.
• Kukonzekera kwazitsamba, komwe kumaphatikizapo kuphipha kwa fir, hawthorn, linden ndi phytoelements, amathanso kugwiritsidwa ntchito pakuchiritsa kovuta kwa cholesterol.
• Kugwiritsa ntchito lipoic acid kumathandizira kupewa kukula kwa atherosulinosis, matenda a mtima komanso, makamaka, kuwongolera kuchuluka kwa cholesterol.

Kukonzekera kochokera pazitsamba zamafuta kumakhala ndizotsatira zoyipa zochepa ndipo kumalekeredwa bwino kuposa ma statins kapena fibroic acid. Komabe, kugwira ntchito kwa zinthu za chomera ndi kuchuluka kwa momwe zimakhudzira cholesterol yokwezeka kumakhala kotsika kwambiri poyerekeza ndi mankhwala omwe amaphatikizidwa ndi ma fibrate kapena ma statins. Chifukwa chake, pakufunika kuti kuchepetsedwa kwambiri kwa cholesterol, kugwiritsa ntchito mapiritsi a adyo kapena mafuta a nsomba kumatha kukhala ngati cholumikizira chithandizo chachikulu.

Kugwiritsanso ntchito kwa mavitamini a vitamini, omwe amaphatikizapo mavitamini a B ndi nicotinic acid, amagwiritsidwanso ntchito kwambiri polimbana ndi cholesterol yayikulu. Kugwiritsira ntchito kukonzekera kwa vitamini kumachepetsa cholesterol m'magazi kumakupatsani mwayi woperekera lipid metabolic, ndipo nicotinic ndi folic acid amakhala ndi mtundu wa triglycerides.

Kukonzekera kochepetsa cholesterol kumachitika mwachangu komanso moyenera. Kutengera zolemba zamankhwala ndi malingaliro onse opanga, chithandizo chamankhwala chitha bwino komanso popanda zovuta zina zoyipa. Kugwiritsa ntchito mankhwala ena omwe amathandizira kutsitsa cholesterol kapena ayi ndikusankha kwa wodwala aliyense. Komabe, munthu ayenera kukumbukira kuti kuchuluka kwa cholesterol komwe kumawopseza kukula kwa matenda amtima wam'matumbo, komwe kumatha kubweretsa stroke, kugunda kwa mtima ndi atherosclerosis. Kulimbikitsa thupi lanu ndiye chinsinsi cha moyo wautali komanso kukhala ndi thanzi labwino.

Gulu lalikulu la mankhwala

Choyamba, mankhwala ochepetsa zamadzimadzi ayenera kukumbukiridwa. Izi zikuphatikiza:

1. mafupa
2. ma statins
3. anion amasinthana mankhwala ndi ma resini omwe amachepetsa kuyamwa kwa cholesterol m'matumbo,
4. nicotinic acid
5. phenucol.

Kutengera momwe amathandizira, mankhwalawa amatha kugawidwa m'magulu angapo:

• mankhwala omwe amalepheretsa kupanga cholesterol otsika kwambiri (amatchedwanso kuti oyipa): ma statin, ma fibrate, nicotinic acid, probucol, atiflavin,
• othandizira omwe amatha kuchepetsa mayamwidwe a cholesterol: magiya, olowa mmimba a ma asidi a bile,
• mafuta kagayidwe okonza kuti kumawonjezera mkulu-kachulukidwe cholesterol: lipostabil, zofunika.

Otsatira a bile acid

Mankhwala omwe bile bile acid amadziwika kuti ma anion exchange resins. Mankhwalawa akangolowa m'matumbo, ma acid amamugwidwa ndikuwachotsa m'thupi.

Wotsirizayo adayankha izi pochititsa kuti mavitamini atsopano a bile azipezeka m'masitolo a cholesterol omwe alipo. Cholesterol imatengedwa kuchokera m'magazi, omwe amathandiza kuchepetsa.

Makampani ogulitsa zamankhwala amapereka mankhwala opangira cholestyramine, komanso colestipol, kuti muchepetse cholesterol yamagazi. Itha kugwiritsidwa ntchito mu Mlingo wa 2-4, ndi kukakamiza koyambirira kwamadzimadzi ndi madzi.

Ma resin osinthana ndi anion sangathe kulowa mu magazi ndi "kugwira ntchito" kokha m'matumbo a lumen. Chifukwa cha izi, mankhwalawa sangathe kukhala ndi vuto lalikulu mthupi.

Zotsatira zoyipa zingaphatikizeponso:

Ngati othandizira okhazikika a bile acids akhala akudya muyezo waukulu kwa nthawi yayitali, ndiye pamenepa mwina pali kuphwanya mayamwidwe mavitamini ena, komanso bile acid.

Mankhwala omwe ali mgululi amachepetsa kuchuluka kwa omwe amadziwika kuti ndi zoipa cholesterol, ndipo kupezeka kwa triglycerides m'magazi kumakhalabe pamlingo womwewo.

Cholesterol Absorption Suppressants

Chifukwa cha kuchepa kwapang'onopang'ono kwa cholesterol kuchokera ku chakudya, gulu la mankhwalawa limatha kuchepetsa kuchepa kwake. Wothandiza kwambiri amakhala gitala. Chowonjezera ichi chopatsa thanzi ndichotetezeka kwathunthu ndipo chimachokera ku mbewu ya nyemba za hyacinth. Zomwe zimapangidwazo zimaphatikizapo polysaccharide, yomwe, polumikizana ndi madzi, imasandulika mafuta.

Guarem imatha kupanga molekyu mamolekyulu am'makoma a matumbo. Kuphatikiza apo, mankhwalawa:

• imathandizira kuchoka kwa bile acid,
• amaletsa kusangalala
• amathandizira kuchepetsa kuchuluka kwa zakudya zomwe zimadyedwa.

Izi zothandizira kuponderezera zili mu mawonekedwe a granules kuti ziwonjezeke kumwa. Kugwiritsa ntchito mankhwalawa kumatha kuphatikizidwa mosavuta ndi njira zina.

Mukamagwiritsa ntchito, mavuto amakhudzanso, mwachitsanzo, kuwonda chopondapo, kupweteka m'matumbo, mseru komanso kutulutsa. Zizindikirozi ndizochepa komanso sizimachitika kawirikawiri. Ngakhale pakalibe chithandizo, amadutsa mwachangu, pomwe pali kuchepa kwadongosolo kwa cholesterol yamagazi.

Nicotinic Acid

Nicotinic acid ndi zotuluka zonse, mwachitsanzo:

kwenikweni, ndi mavitamini a B. Mankhwalawa amachepetsa cholesterol yotsika komanso amathandizira dongosolo la fibrinolysis, lomwe limathandizanso kuchepetsa mwayi wokhala ndi thrombosis. Njira ndizabwino kuposa mankhwala ena ochepetsa lipid kumachulukitsa zomwe zimakhala ndi cholesterol m'magazi a wodwala.

Chithandizo cha nicotinic acid chimatenga nthawi yayitali ndikuwonjezera kovomerezeka. Mukamaliza kukonzekera, musanamwe madzi akumwa otentha, makamaka khofi wachilengedwe.

Niacin amatha kukwiyitsa makoma am'mimba, omwe samapatula magwiritsidwe ake ntchito zilonda zam'mimba. Mwa odwala ambiri, redness ya nkhope imatha kuonedwa koyambirira kwa chithandizo, komabe, chizindikiro ichi chimazimiririka pakapita nthawi. Kuti muchepetse kufiyanso, muyenera kumwa 325 mg wa aspirin theka la ola musanagwiritse ntchito mankhwala.

The contraindication akuluakulu a nikotini acid ndi monga:

• aakulu a chiwindi
• gout
• kutentha kwa mtima.

Pali mankhwala omwe angayambitse zotsatira zoyipa zochepa komanso amakhala nthawi yayitali - awa ndi enduracin.

Ma probucol samakhudzana ndi triglycerides, komanso amawongolera moyenera cholesterol yabwino komanso yoyipa m'magazi. Mapiritsi amaletsa peroxidation wa mafuta ndikuwonetsa kutchulidwa kwa anti-atherosulinotic kwenikweni, okhudza kuchepa kwa mafuta m'thupi.

Zotsatira zamankhwala omwe amapezeka ndi Probucol zitha kupezeka pambuyo pa miyezi iwiri ndipo zimatha mpaka miyezi isanu ndi umodzi atasiya kugwiritsa ntchito. Chidacho chimatha kuphatikizidwa bwino bwino ndi mankhwala ena omwe amachepetsa cholesterol.

Pa mankhwala, kukulitsa gawo la mtima komanso kusokonezeka kwa phokoso la mtima titha kuzindikira. Kuti mupewe izi, ndikofunikira kudutsa electrocardiogram osachepera kamodzi mu miyezi 6.

Ma probucol sangathe kutumikiridwa pa nthawi yomweyo ngati chingwe.

Zotsatira zoyipa za thupi zimaphatikizapo kupweteka pamimba, nseru ndi m'mimba.

Mankhwala sayenera kumwedwa ndi:

• chamkati michere,
• pafupipafupi zochitika za myocardial ischemia,
• magawo otsika a HDL.

Mafashoni amatha kuthana nawo moyenera mulingo wa triglycerides, komanso ndende ya LDL ndi VLDL. Zitha kugwiritsidwa ntchito ndi hypertriglyceridemia yofunika. Otchuka kwambiri amatha kutchedwa mapiritsi:

• gemfibrozil (lopid, gevilon),
• fenofibrate (Tipantil 200 M, Tricor, Exlip),
• cyprofibrate (lipanor),
• choline fenofibrate (trilipix).

Zotsatira zoyipa zoledzeretsa zimatha kudziwidwa ndi kupweteka m'misempha, mseru komanso kupweteka pamimba. Mitengo yowonjezereka imatha kukulitsa kupezeka kwa miyala ya impso ndi chikhodzodzo. Pafupifupi mokwanira, kuletsa kwa hematopoiesis kumatha kuchitika.

Mankhwalawa sangathe kufotokozedwera matenda a impso, chikhodzodzo ndi mavuto am magazi.

Ma Statin ndi mapiritsi ochepetsa kwambiri a cholesterol. Amatha kuletsa enzyme yapadera yomwe imayankha ndikupanga chinthu chonga mafuta m'chiwindi, ndikumachepetsa kuyika kwake m'magazi. Nthawi yomweyo, kuchuluka kwa ma LDL receptors kukukulira, zomwe zimapangitsa kuti chiwopsezo cha kuchotsera kwa cholesterol chotsika kwambiri.

Monga lamulo, mankhwala otsatirawa ndi mankhwala:

• simvastatin (vasilip, chakor, aries, simvageksal, simvakard, simvakor, simvastatin, simvastol, simvor, simlo, sincard, holvasim),
• lovastatin (cardiostatin, choletar),
• pravastatin
• atorvastatin (anvistat, atocor, atomax, ator ,x, atoris, vazator, lipoford, lypimar, liptonorm, novostat, torvazin, torvakard, tulip),
• rosuvastatin (akorta, mtanda, mertenil, rosartark, rosucard, rosulip, roxera, rustor, tevastor),
• pitavastatin (livazo),
• fluvastatin (leskol).

Simvastatin, komanso lovastatin, amapangidwa kuchokera ku bowa. Mankhwala omwewo a mapiritsi a cholesterol okwanira amasintha kukhala metabolites yogwira. Pravastatin ndi fungal yomwe imachokera ku chinthu chomwe chimagwira.

Statin akhoza kukhala olimbikitsidwa kamodzi usiku uliwonse. Malangizo a mankhwalawa amafotokozedwa chifukwa chakuti kuchuluka kwa mafuta amafuta a cholesterol kumachitika usiku. Popita nthawi, mlingo wa ma statins utha kuwonjezereka, ndipo kutha kwake kudzakwaniritsidwa pambuyo masiku owerengeka oyamba, kudzafika patali patatha mwezi umodzi.

Ma Statin ndi otetezeka anthu, koma ndikofunikira kwambiri kuti musagwiritse ntchito Mlingo waukulu, makamaka ndi fibrate, yomwe ili ndi zovuta za chiwindi.

Odwala ena atha kukhala ndi kufooka kwa minofu ndi kupweteka m'thupi. Nthawi zina, kupweteka kwam'mimba, kudzimbidwa, kusanza, komanso kuwonongeka kwathunthu, kusowa tulo komanso kupweteka mutu kumadziwika.

Mankhwalawa ochepetsa cholesterol sangathe kukhudza chakudya cham'mimba komanso purine metabolism, yomwe imawalola kuti azigwiritsidwa ntchito pama degree osiyanasiyana a kunenepa kwambiri, gout ndi matenda ashuga. Dziwani kuti ngati cholesterol yayikulu imawonedwa pa nthawi ya pakati, ndikofunikira kukaonana ndi dokotala.

Ngati tilingalira za mtundu wakale wa mankhwala, ndiye kuti ma statin amatha kulumikizidwa ku chithandizo cha atherosermosis monga monotherapy kapena pamodzi ndi mankhwala ena.

Pharmacology imapereka zophatikizika zopangidwa motengera:

1. lovastatin ndi nikotini acid,
2. ezetimibe ndi simvastatin,
3. pravastatin ndi fenofibrate,
4. rosuvastatin ndi ezetimibe.

Kusintha kwa ma statins ndi acetylsalicylic acid, atorvastatin ndi amlodipine akhoza kumasulidwa.

Kugwiritsa ntchito mankhwala opangidwa okonzekera sikuti kumangopindulitsa kwambiri pochulukitsa ndalama, komanso kumadzetsa zotsatirapo zake zochepa.

Zabwino ndi zotsika mtengo ndi ziti?

Pazinthu zokhala ndi thanzi kapena kupulumutsa miyoyo, mtengo wa mankhwala suyenera kukhala njira yokhayo yosankhira, ngakhale kuti mapiritsi a cholesterol otsika mtengo akhoza kukhala abwino kwambiri. Zonse zimatengera kukhudzika kwa thupi kuzinthu zopangika pamapiritsi ndi kuwonongeka kwa ziwalo ndi hypercholesterolemia (cholesterol yayikulu). Masiku ano, pochiza mikhalidwe iyi, mitundu iwiri ya mankhwala amagwiritsidwa ntchito:

• ma statins (HMG-CoA reductase inhibitors),
• michere (zochokera ku fibroic acid).

Mu gulu la ma statins, mapiritsi a cholesterol omwe amagwiritsidwa ntchito:

• atorvastatin,
• lovastatin
• pitavastatin
• pravastatin
• rosuvastatin,
• simvastatin
• fluvastatin.

Masango a fibrate amayimiriridwa ndi zinthu zomwe zimagwira ntchito:

• bezafibrat,
• fenofibrate
• choline fenofibrate,
• kaprofibrate.

Mwa mankhwala a magulu awa, mutha kusankha mapiritsi otsika mtengo a cholesterol. Mayina amalonda amankhwala amatha kusiyanasiyana kuchokera pazomwe zimagwiritsidwa ntchito), chifukwa chake ndibwino kupatsa mankhwala kwa dokotala.

Mankhwala otchuka kwambiri

Mndandanda wa mayina a mankhwala abwino kwambiri

Munthu akafuna kupeza mndandanda wa mayina a mankhwala abwino kwambiri, sayenera kupita ku malo ogulitsira, koma kupita ku chipatala ndikuyamba onetsetsani kuti akufunikira kwambiri mapiritsi a cholesterol.

Zabwino kwambiri nthawi zambiri zimaphatikizapo mankhwala opangidwa kuti aziganizira zolakwika zonse zamankhwala am'mbuyomu omwe adawoneka mwa machitidwe azachipatala. Tikuyankhula zamankhwala aposachedwa kwambiri aomwe akuti mibadwo yapitayi, ali m'gulu la ma statins, komanso gulu la ma fibrate, ndi mankhwala ena. Inde, mtengo wa mankhwalawa ndiwokwera kwambiri kuposa mtengo wa mapiritsi "wamba" a cholesterol. Timapereka mndandanda wa mankhwala ochepetsa kwambiri (okwera) a lipid omwe amatsitsa patebulopo.

Zizindikiro zochepetsa LDL m'magazi

Monga tikuwonera patebulopo, ma statin amaimira gulu lalikulu kwambiri la mankhwala kuti achepetse cholesterol yamagazi. Ngakhale gululi lamankhwala silimayambitsa kudalirika kwathunthu kwa odwala kapena madokotala chifukwa cha kuwonetsa kokhazikika komwe kumachitika pakachitika chithandizo. Malangizo a mapiritsiwa ali ndi mndandanda wa "kilomita". Ichi ndichifukwa chake kuli kofunikira kuzidziwa nokha ndi mankhwala ochepetsa awa a lipid mwatsatanetsatane.

Kuti owerenga athe kumvetsetsa kukula kwa zomwe apanga pamalondawa, tikupereka ziwerengero zotsatirazi:

• pagulu la statins pali zinthu 7 zazikulu (maina awo aperekedwa pamwambapa),
• pali zizindikiro za 88 za mankhwala a statin,
• pagulu lamankhwala onse amtunduwu opanga osiyana amaposa 3,500 mayina.

Zikuwonekeratu kuti ndizosatheka kutchula mayina onse, chifukwa chake tiziwonetsa kwambiri pa otchuka kwambiri.

Atorvastatin

Mankhwala ochepetsa cholesterol Atorvasatin amapezeka kwa opanga ambiri omwe ali m'maiko osiyanasiyana. The yogwira ndi atorvastatin calcium, yomwe ili m'gulu la pharmacotherapeutic mankhwala opangira lipid-otsitsa, osankha zoletsa za HMG-CoA reductase. Zotsatira zake ndikuchepetsa milingo ya ma lipoprotein otsika kwambiri komanso otsika kwambiri (LDL ndi VLDL), triglycerides ndi apolipoprotein B poletsa kaphatikizidwe ka cholesterol m'chiwindi. Kuphatikiza apo, motsogozedwa ndi atorvastatin, mulingo wa HDL - lipoproteins yapamwamba ukuwonjezeka pang'ono.

Gulu la makampani opanga mankhwala Krka ndi nthambi zawo amatulutsa mapiritsi a cholesterol Atoris omwe ali ndi yogwira mankhwala atorvastatin. Monga ma statins ambiri, ali ndi kutsimikizika kotha kuchepetsa chiopsezo cha zovuta monga angina pectoris ndi matenda amtima (26 ndi 16%, motsatana). Zimalepheretsa kutsegula kwa ma macrophages, kupewa kupindika kwa zolembedwa za atherosrance.

Zophatikizidwa muzochitika za ma statins:

• ndi matenda a chiwindi ndi kuchuluka kwa ma transaminases nthawi zopitilira 3 kuchokera kumtunda wapamwamba kwambiri,
• kuchepa kwa mkaka wa lactase ndi zinthu zina zokhudzana ndi tsankho la lactose,
• ndi mafupa amisempha
• Mimba ndi kuyamwa
• wosakwana zaka 18.

Mapiritsi amapezeka mu Mlingo wa 30, 60 ndi 80 mg. Maonekedwe - mapiritsi oyera a convex azungulira kapena mawonekedwe ozungulira.

Kuchepetsa kuchuluka kwa cholesterol ndikuchepetsa zovuta za mtima, malinga ndi malangizo ogwiritsira ntchito, mankhwalawa Novostat amapangidwanso (chonde - onani osati Novostatin). Nthawi zina alendo omwe amapita ku malo ogulitsa mankhwala (makamaka omwe amafunafuna mapiritsi kuti achepetse cholesterol malinga ndi malingaliro a anzawo) amasokoneza dzina la mankhwalawo ndi mankhwala ena ndikuwapempha kuti awapatse nthano ya Novostatin iyi. Odwala opanda chiyembekezo ngati amenewa sayenera kudabwitsidwa akapatsidwa antifungal Nystatin m'malo mwa lipid-kuchepetsa.

Novostat imakhazikitsidwa pa atorvastatin ndipo ili ndi zinthu zonse za pharmacodynamic zomwe zimagwira.

Kampani yaku Czech yomwe Zentiva imapanga mapiritsi atorvastatin ofotokoza Torvacard cholesterol. Monga mankhwala onse omwe ali ndi chophatikizira ichi, malangizo omwe agwiritsidwe ntchito ndi akulu kwambiri, zomwe zikuwonetsa kufunikira kogwiritsa ntchito mosamala komanso moyenera Torvacard Zotsatira zoyipa kwambiri - hyperglycemia, dyspepsia, flatulence, kusanza, kudzimbidwa, kupindika, chiwindi kukomoka, kupweteka mutu, matupi awo sagwirizana - ndizofanana ndi mankhwala ambiri a statin.

Rosuvastatin

Mapiritsi okhala ndi chinthu chofanana ndi mapiritsi a pinki ozungulira. Kapangidwe kake ka rosuvastatin ndi ofanana ndi pharmacodynamics a ma statins onse, thunthu ndi la subtype la mpikisano, kusankha zoletsa za HMG-CoA reductase. Apatsidwa:

• ndi hypercholesterolemia ya pulayimale, yosakanikirana, komanso cholowa,
• hypertriglyceridemia,
• kutsitsa cholesterol mu atherosulinosis kuti tilepheretse kupita patsogolo.

Rosuvastatin imagwira ntchito poletsa CVD komanso mavuto a odwala omwe ali pachiwopsezo monga matenda oopsa, kuyerekezera kwapabanja matenda am'mitsempha, komanso chikonga.

Calcium ndi Rosuvastatin Calcium ndi gawo limodzi la mapiritsi a Roxer opangidwa ndi Krka. Awa ndi mapiritsi oyera oyera a “vesi” mbali imodzi. Omwe amachokera, monga mapiritsi a cholesterol omwe ali pamwambapa, ali ndi lactose, yomwe odwala omwe ali ndi vuto la shuga la mkaka ayenera kuzindikira.

Rosart hypolipidemic wothandizira ndi wa gulu la mapiritsi amtengo wotsika mtengo wa cholesterol kutengera rosuvastatin. Imapezeka m'malo anayi:

• 5 mg - mapiritsi oyera oyera okhala ndi "ST1" mbali imodzi,
• 10 mg - apinki, mapiritsi ozungulira, olembedwa "ST2",
• 20 mg - mapiritsi ozungulira a pinki, olembedwa "ST3",
• 40 mg - mapiritsi ali ndi mawonekedwe ozungulira ndipo amalemba "ST4".

Mapiritsi a Krestor amapangidwa ndi nthambi zosiyanasiyana za kampani yaku Britain a Astra Zeneca ndipo ndi omwe amaphunziridwa kwambiri ndi mtundu wa rosuvastatin. Pachifukwachi, amaonedwa kuti ndi amodzi mwa abwino (osati otsika mtengo) omwe ali mgulu la mankhwala ochepetsa lipid. Mapiritsi apakale ndiosavuta kusiyanitsidwa ndi chipolopolo chowoneka chikaso ndipo chikaphatikizidwa "ZD45225" mbali imodzi.

Nthanthi yopangidwa ndi Czech-Rosucard ya ku Czech (chophatikizacho chimaganiziridwa kuti dzina) chikupezeka muzosankha zitatu:

• 10 mg - mapiritsi a pinki opepuka kwambiri okhala ndi chipolopolo,
• 20 mg - ofanana ndi akale, koma osiyana maonekedwe a chipolopolo, apa ndi pinki,
• 40 mg ndi mapiritsi a pinki akuda.

Rosucard imanenanso za mapiritsi okwera mtengo, ngakhale mndandanda wazotsatira zoyipa ndizosagwiritsa ntchito sizifupika kuposa zomwe zimapezeka ma statin ena. Ngati mumwa mankhwalawa monga mukuwunenera komanso moyang'aniridwa ndi dokotala, chiopsezo cha zovuta ndizochepa.

Mankhwala ena apamwamba a cholesterol

Ngati, mutatha kukumana ndi ma statins, kufunitsitsa kuthandizidwa nawo kumachepa (ndipo odwala ambiri amawopa kuwatenga), ndikofunikira kulabadira mankhwala ena omwe amachepetsa cholesterol. Awa ndi mankhwala a gulu la fibrate - zotumphukira za fibroic acid, zomwe zimathandizira lipolysis ndikuchotsa zomwe zimatchedwa atherogenic lipoproteins (LDL ndi VLDL) kuchokera m'magazi, komanso kuchepetsa kuchuluka kwa triglycerides. Mapiritsi awa a cholesterol siotsika mtengo, koma mutha kujambula mapangidwe opangidwa ndi Turkey (mwachitsanzo, Lipofen), omwe amakhala otsika mtengo kuposa 2 mapiritsi aku France.

Kuphatikiza pa ma fibrate ndi ma statins, lipid-kuchepetsa yotsika imagwiritsa ntchito cholesterol mayamwidwe ndi yogwira mankhwala ezetimibe (Ezetrol), yomwe imasankha zoletsa (kutsekereza) kuyamwa kwa cholesterol yochokera ku mbewu ndi ma sterols m'matumbo.

Chili bwino ndikumwa chiyani?

Kodi mungasankhe chiyani pamndandanda wamankhwala osokoneza ngati awa, omwe ndibwino kumwa? Ma Statin ndi ma fibrate amawopsya ndi zomwe zimachitika pachiwindi ndi minofu yamafupa, mankhwala aposachedwa kwambiri ndiokwera mtengo kwambiri. Madokotala amalimbikitsa kuti muthe kuyamba kugwiritsa ntchito mankhwala osokoneza bongo mosamala ndipo ngati zingatheke kuti mutha kugwiritsa ntchito bwino komanso moyenera, mutha kulandira chithandizo chokwanira.

Ngati ma statins kapena ma fiber sakukwanira, pali mapiritsi ena ochokera m'magulu a cholesterol mayamwidwe othandizira kapena othandizira kutengera iwo.

Nthawi zina mumatha kumva kuti Bioactive supplement (BAA) Energy ikhoza kugwiritsidwa ntchito ngati mapiritsi a cholesterol. Koma malinga ndi malangizo ogwiritsira ntchito, zinthu zomwe zili ndi dzina la malonda a Energia ndi mavitamini ndi michere yama mineral omwe amapangidwira anthu omwe ali ndi vuto loperewera komanso mavitamini. Zowona kuti Energy ndi mapiritsi a cholesterol sizinatchulidwe mu annotation. Mankhwala nthawi zambiri samakhala mankhwala, ngakhalenso chosangalatsa cha kagayidwe, motero, sibwino kuti apatsidwe ntchito yotsitsa lipid.

Odwala amatha kusokoneza Energy pogwiritsa ntchito lipid-kuchepetsa ya Italy kapena ya Singapore yomwe imapangidwa ndi Simvastatin ndi ezetimibe (statin ndi cholesterol mayamwidwe). Uwu ndi mankhwala abwino kwambiri a hypercholesterolemia.

Ndikofunikira kunena za mapiritsi a Alisat (kapena "Garlic"), omwe ambiri amawawona ngati mapiritsi a cholesterol. Zakudya zowonjezera izi zimapangidwira kuti mudzazitse thupi kuperewera kwa allicin, chinthu chachilengedwe chokhala ndi antifungal ndi bactericidal katundu.

Ngati mukufunadi kulandira chithandizo osati mapiritsi a cholesterol, koma ndi zakudya zowonjezera zakudya, mutha kulabadira makapisozi a Aterolex omwe amathandizira kukonza kagayidwe ka lipid, kugwirizanitsa kugwiritsa ntchito kwawo ndi dokotala.

Kodi ndi zotsika mtengo ziti?

Ngati mungasankhe mankhwala kuti muchepetse cholesterol yamagazi kuchokera pagulu lotsika, ndiye muyenera kuyang'ana pakati pa mankhwala a gulu la statin:

• Atorvastatin (wokhala ndi chinthu chomwecho),
• Cardiostatin (lovastatin),
• Reddistatin (rosuvastatin),
• Vasilip (simvastatin).

Masiku ano, awa ndi mankhwala otsika mtengo kwambiri a cholesterol yamagazi ambiri.

Ndi zochepa zoyipa

Cholinga chachikulu pakuphatikiza mankhwala atsopano ndikuchepetsa kuchuluka kwa zoyipa ndikusungabe mphamvu ya mankhwalawo. Chifukwa chake, mapiritsi a cholesterol am'badwo watsopano - zoletsa za kuyamwa kwa cholesterol m'matumbo (Ezetrol) - amatengedwa ngati mankhwala otetezeka a lipid ochepetsa. Izi sizikutanthauza kuti mankhwalawa alibe zotsatira zoyipa - ali ndipo mndandanda wawo ndi waukulu. Koma malingana ndi malangizo ogwiritsira ntchito, mawonekedwe osafunikira awa amawonekera m'magulu "mosasintha" komanso "kawirikawiri", omwe amalankhula motetezeka.

Kodi ndizotheka kuchepetsa mwachangu komanso moyenera?

Ndizovuta kwa munthu yemwe samazolowera kutsatira nyengo kuti avomereze kufunika kumwa mankhwalawa kwa nthawi yayitali ndikutsatira zakudya. Odwala oterewa ndi osaleza mtima ndipo akufunafuna mapiritsi omwe amachepetsa cholesterol mwachangu komanso moyenera. Ndipo sipangakhale mapiritsi oterowo, popeza kubwezeretsa kwa mafuta kagayidwe kofunika kukhazikika m'magazi a cholesterol m'mwazi kumatenga nthawi yayitali. N`zosatheka kuchiritsa matenda okhala ndi mapiritsi angapo, omwe nthawi zina amapangidwa kwa zaka zambiri. Chifukwa chake, odwala omwe ali ndi hypercholesterolemia ayenera kukhala okonzekera chithandizo cha nthawi yayitali komanso kusintha kwakukuru m'moyo.

Ndemanga Ndemanga

Kuunikanso kwa odwala zinthu zosiyanasiyana zogwiritsidwa ntchito ndi mankhwala a lipid-osangalatsa ndizosangalatsa, kukuthandizani kuti mumvetsetse kuti ndi uti mwa iwo omwe amaloledwa bwino, omwe ndi othandiza kwambiri.

Malinga ndikuwunika kwa odwala, ambiri a iwo amathandizidwa ndi ma statins omwe amapatsidwa iwo kuchipatala. Kuchokera pagululi la mankhwalawa, mapiritsi a atorvastatin ndi rosuvastatin based cholesterol adalandira ndemanga zabwino. Mwa njira, rosuvastatin amatchedwa opambana, popeza munthawi ya makonzedwe ake odwala ambiri sanakumanepo ndi mavuto.

Pakati pa fiber, Tricor adalandira ndemanga zabwino.

Ezetrol amatchedwa piritsi la cholesterol labwino koposa, koma madokotala ndi odwala onse amawona kuti "ndi mankhwala okwera mtengo osatheka."

Momwe mungachepetse cholesterol popanda mankhwala?

Popeza kuopsa ndi kuwonongera kwa ndalama, odwala ambiri amafunafuna njira ina yopanda mankhwala yochepetsera lipid. Ndipo njira zotere zilipo, ngakhale zimafunikira kulimbikira kwapadera, kulanga ndi kudekha, popeza njira izi sizipereka mwachangu zotsatira. Ndi funso loti tichotse zinthu zoyambitsa matenda zomwe zimapangitsa kuti mapapo a metabolism asokonezeke ngati kusachita zinthu zolimbitsa thupi, zizolowezi zoyipa komanso kuperewera kwa zakudya m'thupi.

Kuphatikizika kwa njira zosagwiritsa ntchito mankhwala kuyenera kuphatikizapo bungwe la regimen la tsikulo ndikupumula koyenera komanso kuchepetsa kupsinjika.

Mutatha kukonza zakudya zamavuto, mutha kumasula chida chanu chogaya kuchokera pakufunika kuti mupeze mafuta ochulukirapo komanso ma secrechides, omwe angakhudze mbiri ya lipid. Ndi kukhazikika kuchuluka kwa mafuta m'thupi m'magazi, ndikofunikira kusunga zakudya zapadera zomwe zimapangitsa kuchepetsa matenda.

Moyo wokangalika

Zosakwanira zolimbitsa thupi kumabweretsa kukokomeza magazi ndikuchokera (deposition) yamagetsi osagwiritsidwa ntchito mu mawonekedwe a mafuta ochulukirapo m'thupi. Amasungidwa pafupifupi ziwalo zonse zofunika, zimasokoneza momwe zimagwirira ntchito ndikusokoneza mafuta achilengedwe. Kusintha moyo wazinthu zolimbitsa thupi kumawonjezera kusintha kwa magazi ndi kusintha njira zonse, kuphatikizapo mafuta kagayidwe. Ichi ndichifukwa chake ndikofunikira kuchita masewera olimbitsa thupi pafupipafupi - masewera olimbitsa thupi m'mawa, kuthamanga, kuyenda, kusambira kangapo pa sabata, kulimbitsa thupi pafupipafupi pantchito (makamaka ngati kungokhala).

Kuyeretsa ziwiya ndi wowerengeka azitsamba

Zithandizo za Folk zidapezanso malo a lipid-kuchepetsa mankhwala. Zachilengedwe zimakhala ndi zomerazi zomwe zimathandizira kukonza njira zama metabolic komanso kuwonongeka kwa mafuta. Izi ndi maziko a maphikidwe a mankhwala omwe amayeretsa magazi ndi kutsitsa cholesterol. Mukayamba mankhwala ochizira wowerengeka, muyenera kukumbukira kuti mankhwala azitsamba ndiwotalikitsa, ndipo amakhalanso ndi zovuta komanso zotsutsana.