Humalog ndi chithunzi chopangidwa cha insulin yofupikitsa anthu. Imayendetsa kagayidwe ka glucose m'thupi, kuchepetsa magazi ake. Poterepa, kuchuluka kwa glucose mu mawonekedwe a glycogen kumadziunjikira minofu ndi chiwindi. Insulin Humalog imathandizira kapangidwe kazinthu zomanga thupi, kumwa ma amino acid, kuchepetsa kuchepa kwa glycogen kupita ku glucose, ndikuchepetsa kupanga kwa glucose kuchokera m'mafuta ndi mapuloteni.

Insulin yofupikitsa nthawi zambiri imaphatikizidwa ndi basal yopewa magazi. Kutalika kwa zochita za Humalog kumasiyana pakati pa odwala osiyanasiyana ndipo zimatengera zinthu zambiri.

Pankhani ya matenda a shuga 2, pamene wodwala amalandira mapiritsi amodzi munthawi yomweyo mapiritsi ndi insulin, kuwongolera shuga kumakhala wodalirika kwambiri. Izi zimawonetsedwa kuchepa kwa mphamvu ya hemoglobin ya glycated panthawi yowunika chithandizo. Humalog imachepetsa pafupipafupi kuchepetsa shuga m'magazi usiku. Mkhalidwe wa chiwindi ndi impso za wodwalayo sizikhudza kagayidwe ka mankhwala.

Malinga ndi malangizowo, Humalog imatengedwa mwachangu ndipo imayamba kugwira ntchito mphindi 15 pambuyo pa kuwongolera, motero imatha kutumizidwa mphindi 15 asanadye, mosiyana ndi ma insulin ena achidule, omwe amatengedwa mphindi 30 mpaka 45. Kutalika kwake ndi kufupikirapo kuposa insulin wamba yamunthu, ndipo ndi maola 2 - 5 okha.

Malangizo ogwiritsira ntchito Humalog

Mankhwalawa amaperekedwa pang'onopang'ono jekeseni kapena pampu ya insulin musanadye. Masamba obayira ndi mapewa, ntchafu, pamimba kapena matako. Muyenera kuwasinthanitsa kuti m'malo amodzi jakisoni asabwerezedwe kawiri m'mwezi umodzi, izi zitha kupewa kuchepa kwa minyewa. Tiyenera kuyesetsa kuti tisalowe m'mitsempha yamagazi. Osapaka jakisoni pamalo atabayidwa kuti mupeze bwino mankhwalawa.

Muzochitika zofunikira, Humalog insulin imatha kuperekedwa kudzera mu minyewa yothandizira (opaleshoni, ketoacidosis, etc.). Pamaso jakisoni, onetsetsani kuti yankho limawotha kutentha kwa chipinda.

Mlingo wa Humalog ndiwothandiza pa wodwala aliyense ndipo amawerengedwa ndi dokotala. Osasakaniza ma insulini osiyanasiyana mu cholembera.

Humalog siigwira ntchito bwino mukamamwa pamodzi ndi glucocorticoids, njira zakulera zam'kamwa, mankhwala a chithokomiro, komanso nicotinic acid. Ethanol, salicylates, ACE zoletsa, beta-blockers amawonjezera mphamvu ya insulin.

Pa nthawi yoyembekezera komanso mkaka wa m'mawere, kayendetsedwe ka insulin kameneka ndi kovomerezeka, koma kuwunika kwambiri misempha ya magazi ndikofunikira. Mukamayamwitsa, kukumbukira momwe mankhwalawa nthawi zambiri amafunikira chifukwa chofunikira kwambiri cha insulini. Mankhwala amavomerezedwa kuti azigwiritsidwa ntchito mwa ana.

Zotsatira zoyipa

Nthawi zina wokhala ndi mankhwala osokoneza bongo kapena mawonekedwe amodzi amomwe thupi limapangira, Humalog imatha kupangitsa kuchepa kwa shuga wamagazi - hypoglycemia.

Nthawi zina, pali matupi awo sagwirizana ndi mankhwalawa mu mawonekedwe a totupa, redness, kuyabwa kwa khungu, m'malo ovuta - angioedema.

Pomwe jakisoni, kufalikira kwa gawo lochepa wamafuta, lipodystrophy, zitha kudziwika.

Makhalidwe ndi malangizo ogwiritsira ntchito insulin Humalog

Mwa zina mwa mankhwala omwe amapezeka ndi insulin ambiri amatha kutchedwa Humalog. Mankhwala akupangidwa ku Switzerland.

Zimakhazikitsidwa ndi insulin Lizpro ndipo cholinga chake ndikuchizira matenda ashuga.

Mankhwala ayenera kuikidwa ndi dokotala. Ayeneranso kufotokozera malamulo omwera mankhwalawo kuti mupewe mavuto. Mankhwalawa amagulitsidwa kokha ndi mankhwala.

Zambiri ndi mankhwala a pharmacological

Humalog ili mu mawonekedwe a kuyimitsidwa kapena jakisoni. Kuyimitsidwa kumakhala koyera komanso kutengera kupangika. Njira yothetsera vutoli ndi yopanda utoto komanso wopanda fungo, yowonekera.

Chofunikira kwambiri pakuphatikizidwa ndi Lizpro insulin.

Kuphatikiza apo, zosakaniza monga:

• madzi
• metacresol
• zinc oxide
• glycerol
• sodium hydrogen phosphate heptahydrate,
• sodium hydroxide solution.

Chogulitsachi chimagulitsidwa m'mak cartridge atatu. Makatoni ali mu cholembera cha Quickpen, zidutswa 5 pa paketi imodzi.

Komanso pali mitundu ya mankhwalawa, yomwe imaphatikizapo yankho laling'ono la insulin komanso kuyimitsidwa kwa protamine. Amadziwika kuti Humalog Remix 25 ndi Humalog Remix 50.

Lizpro insulin ndi mawonekedwe a insulin yaumunthu ndipo amadziwika ndi zomwezi. Zimathandizira kukulitsa kuchuluka kwa shuga. Pulogalamu yogwira imagwira pama cell membrane, chifukwa choti shuga kuchokera m'magazi amalowa m'matumbo ndipo amawagawa. Zimathandizanso kupanga mapuloteni omwe amagwira ntchito.

Mankhwala amadziwika ndi kuchitapo kanthu mwachangu. Zotsatira zimawonekera mkati mwa kotala la ola mutatha jakisoni. Koma imapitilira kwakanthawi. Hafu ya moyo wa zinthu zimafunika pafupifupi 2 hours. Nthawi yowonetsera kwambiri ndi maola 5, omwe amathandizidwa ndi mawonekedwe a thupi la wodwalayo.

Zizindikiro ndi contraindication

Chizindikiro chogwiritsira ntchito mankhwala omwe ali ndi insulin ndi:

• lembani matenda ashuga 1 omwe amadalira insulini (osalolera mitundu ina ya insulini),
• lembani matenda a shuga omwe amadalira insulin (ngati mankhwalawa ali ndi mankhwala ena)
• anakonzekera kuchitapo kanthu opaleshoni
• matenda ashuga omwe adayamba panthawi ya gestation (gestational).

Muzochitika izi, mankhwala a insulin amafunikira. Koma Humalog iyenera kusankhidwa ndi adotolo atatha kuphunzira chithunzi cha matendawa. Mankhwalawa ali ndi zotsutsana zina. Muyenera kuwonetsetsa kuti kulibe, apo ayi pamakhala zovuta za zovuta.

Izi zikuphatikiza:

• kupezeka kwa hypoglycemia (kapena kupezeka kwake),
• ziwengo kuti zikuchokera.

Ndi izi, adotolo ayenera kusankha mtundu wina wa mankhwala. Kusamala ndikofunikanso ngati wodwala ali ndi matenda ena owonjezera (matenda a chiwindi ndi impso), chifukwa chifukwa cha iwo, kufunikira kwa insulin kumatha kufooka. Chifukwa chake, odwala otere ayenera kusintha mlingo wa mankhwalawa.

Odwala Apadera ndi Mayendedwe

Mukamagwiritsa ntchito Humalog, kusamala kwina kumafunikira pokhudzana ndi magulu apadera a odwala. Matupi awo amatha kukhala osamala kwambiri ndi zovuta za insulin, motero muyenera kukhala anzeru.

Zina mwa izo ndi:

1. Amayi pa nthawi yoyembekezera. Mwachidziwitso, chithandizo cha matenda a shuga mwa odwala amaloledwa. Malinga ndi zotsatira za kafukufuku, mankhwalawa samavulaza kukula kwa mwana wosabadwayo ndipo samayambitsa mimbayo. Koma ziyenera kukumbukiridwa kuti munthawi imeneyi kuchuluka kwa shuga m'magazi kumatha kukhala kosiyana panthawi zosiyanasiyana. Izi ziyenera kuyang'aniridwa kuti mupewe zotsatira zoyipa.
2. Amayi oyamwitsa. Kulowetsedwa kwa insulin mkaka wa m'mawere sikowopsa kwa akhanda. Izi zimachokera kumapuloteni ndipo zimatengedwa m'matumbo a mwana. Chenjezo lokha ndiloti azimayi omwe amadyetsa mwachilengedwe ayenera kudya.

Kwa ana ndi okalamba posakhala ndi mavuto azaumoyo, chisamaliro chapadera sichofunikira. Humalog ndi yoyenera kulandira chithandizo chawo, ndipo adotolo ayenera kusankha mlingo wotsatira mawonekedwe a matendawa.

Kugwiritsa ntchito Humalog kumafunikira kukonzekereratu poyerekeza ndi matenda ena oyipa.

Izi zikuphatikiza:

1. Kuphwanya chiwindi. Ngati chiwalochi chikugwira ntchito moyipa kuposa momwe chikufunikira, ndiye kuti mankhwalawo atha kukhala ochulukirapo, zomwe zimabweretsa zovuta, komanso kukula kwa hypoglycemia. Chifukwa chake, pakakhala kulephera kwa chiwindi, mlingo wa Humalog uyenera kuchepetsedwa.
2. Mavuto a impso. Ngati alipo, palinso kuchepa kwa kufunika kwa insulin. Pankhaniyi, muyenera kuwerengera mosamala ndi kuyang'anira njira yochiritsira. Kukhalapo kwa vuto lotere kumafuna kupenda kwakanthawi.

Humalog imatha kuyambitsa hypoglycemia, chifukwa chomwe kuthamanga kwazomwe zimachitika komanso kuthekera kwazomwe zimayang'ana zimasokonezedwa.

Chizungulire, kufooka, kusokonezeka - zinthu zonsezi zimatha kugwira ntchito kwa wodwala. Zochita zomwe zimafunikira kuthamanga komanso kusokonezedwa zimatha kukhala zosatheka kwa iye. Koma mankhwalawo pawokha samakhudza izi.

Zotsatira za pharmacological

Humalog ndi DNA yobwerezabwereza yokwaniritsa ya insulin ya anthu.

Chochita chachikulu cha Humalog ndicholinga chowongolera kagayidwe ka glucose. Komanso, mankhwalawa ali ndi vuto la anabolic, chifukwa zomwe zimapangitsa mafuta acids, glycerol, glycogen mu minofu minofu kumawonjezera, komanso kuwonjezeka kwa kumwa kwama amino acid komanso kuchuluka kwa mapuloteni. Pankhaniyi, pali kuchepa kwa gluconeogenesis, glycogenolysis, lipolysis, ketogeneis komanso kumasulidwa kwa amino acid.

Poyerekeza ndi mtundu wa shuga wa mitundu 1 ndi 2, mukamagwiritsa ntchito Humalog, poyerekeza ndi insulin yaumunthu, pali kuchepa kwakukulu kwa hyperglycemia yomwe imachitika mutatha kudya. Kuti mukwaniritse kuchuluka kwa shuga m'magazi, mulingo woyenera waifupi komanso insulin yoyambira uyenera kusankhidwa.

Kutalika kwa Humalogue kumasiyana malinga ndi matendawa, komanso momwe munthu akuonekera, tsamba la jakisoni, mawonekedwe a magazi ndi kutentha kwa thupi.

Palibe kusiyana kwakukulu pakugwiritsa ntchito Humalog mwa akulu ndi ana.

Kuyankha kwa glucodynamic pamankhwala ndi Humalog sikudziyimira pawokha kapena kulephera kwa impso.

Mankhwala othandizira a Humalog ndi ofanana ndi insulin yaumunthu, koma amadziwika ndi kuyamba mwachangu (mkati mphindi 15), komanso nthawi yayifupi (kuyambira maola 2 mpaka 5).

Mlingo ndi makonzedwe

Mlingo umodzi wa insulin Humalog wopangidwa ndi dokotala aliyense payekhapayekha. Mutha kulowa mankhwalawa musanadye chakudya, ndipo nthawi zina mukatha kutero.

Kutentha kwa yankho kuyenera kukhala kutentha pang'ono kwa chipinda.

Nthawi zambiri, mankhwalawa amathandizidwa mosazungulira (mwa jakisoni kapena kulowetsedwa kwa nthawi yayitali pogwiritsa ntchito insulin pampu, phewa, m'mimba kapena matako. Potere, tsamba la jakisoni liyenera kusinthidwa kuti malo amodzi asagwiritsidwe ntchito koposa kamodzi pamwezi. Mukamapereka yankho la Humalog, muyenera kusamala kuti musalowe mu kayendedwe kazinthu.

Malinga ndi zomwe zikuwonetsa (motsutsana ndi ketoacidosis, matenda owopsa, komanso nthawi ya postoperative kapena nthawi yayitali) Humalog imayendetsedwa kudzera m'mitsetse yamkati.

Pakuperekedwa, Mlingo woyenera uyenera kutsatiridwa kuti mupewe mankhwala osokoneza bongo, omwe amatha kuwonetsa ngati hypoglycemia, limodzi ndi ulesi, kuchuluka thukuta, tachycardia, kupweteka kwa mutu, kusanza, ndi chisokonezo. Monga lamulo, shuga kapena mankhwala ena kapena zinthu zokhala ndi shuga zimagwiritsidwa ntchito pochiza.

Kuwongolera kwambiri hypoglycemia, kutsitsa kapena kugwiriridwa kwa glucagon kumagwiritsidwa ntchito, ndipo pambuyo pokhazikika, chakudya chimapangidwira mkati. Pofuna kupewa kubwereza kwa hypoglycemia, kudya mafuta ochulukirapo kungafunike.

Kuyanjana kwa mankhwala osokoneza bongo

Pa mankhwala, ziyenera kukumbukiridwa kuti kuchuluka kwa hypoglycemic ya Humalog insulin kumatha kuchepetsa kwambiri kugwiritsidwa ntchito kwa njira zakulera za pakamwa, glucocorticosteroids, mankhwala a chithokomiro, danazole, nicotinic acid, beta2-adrenergic agonists (kuphatikiza salbutamol, ritodrin ndi terbutaline acid. thiazide diuretics, diazoxide, lithiamu carbonate, isoniazid, phenothiazine.

Amveke Humalog kanthu hypoglycemic ankaziona pamene ntchito ndi beta-blockers, Mowa ndi Mowa-munali mankhwala, anabolic mankhwala, fenfluramine, guanethidine, tetracyclines, mankhwala m'kamwa hypoglycemic, salicylates, sulfonamides, Mao zoletsa ndi Ace, octreotide, angiotensin II cholandilira muzikangana.

Sitikulimbikitsidwa kusakaniza Humalog ndi mankhwala okhala ndi insulin ya nyama.

Moyang'aniridwa ndi dokotala, Humalog molingana ndi malangizo angagwiritsidwe ntchito nthawi imodzi ndi insulin yaumunthu, yomwe imakhala yotalikirapo, kapena ndi mankhwala a hypoglycemic (sulfonylurea derivatives).

Mimba komanso kuyamwa

Phunziroli, palibe zotsatira zoyipa za Humalog pa mwana wosabadwayo kapena mayi, koma palibe kafukufuku wofanana yemwe adachitika.

Pa nthawi yoyembekezera, Humalog imayang'aniridwa kuti azisamalira machitidwe a shuga pang'onopang'ono chifukwa cha matenda a shuga. Monga lamulo, kufunika kwa insulini kumachepa mu trimester yoyamba ndikuwonjezereka kwa atatu trimesters a mimba. Kufunika kwa insulin kumatha kuchepa kwambiri pakubadwa kwa mwana, komanso pambuyo pawo.

Pankhani ya matenda a shuga, ndikofunikira kudziwitsa dokotalayo nthawi yakusamba kwa kubereka, popeza nthawi imeneyi ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga.

Panthawi yoyamwitsa, ndikofunikira kusintha mlingo wa Humalog yoyikidwa.

Kodi insulin ya insulin ndi chiyani?

Pakadali pano, kuti akwaniritse chipukuta chokhazikika, mankhwala osiyanasiyana komanso kuphatikiza kwawo kumagwiritsidwa ntchito. Odwala ambiri M'mayiko osiyanasiyana amayamikiranso njira zina zomwe amapangira jekeseni theka la ola asanadye, pogwiritsa ntchito njira imodzi yaposachedwa yopanga insulin Humalog.

Mankhwalawa ndiwothandiza kwambiri makamaka ngati odwala matenda ashuga ocheperapo kwambiri, chifukwa sizovuta kuwerengetsa pafupifupi chilimbikitso cha mwana, ndipo ndizosatheka kuchotsa mahomoni omwe adayambitsidwa kale m'thupi. Koma jakisoni mukangodya kumene pankhaniyi ndiye chisankho choyenera.

Kusintha kwa lispro kumachitika pazifukwa zingapo. Nthawi zambiri, mankhwalawa amasankhidwa ndi anthu omwe safuna kukhala ndi chizolowezi chatsiku ndi tsiku.

Komanso, mankhwalawa amaperekedwa kwa odwala omwe ali ndi zovuta za matenda a shuga, akukonzekera opareshoni, achinyamata ndi ana a zaka zoyambirira za moyo. Mothandizidwa ndi mankhwalawa, DM 2, yomwe singayankhe mankhwala ochepetsa shuga, imatha kuwongoleredwa mosavuta.

Nthawi zambiri mahomoniwa amaphatikizidwa ndi ena owonjezera monga Lantus kapena Levemir.

Kugwiritsa ntchito mankhwalawa pa nthawi ya pakati kumapereka zotsatira zabwino zowongolera glycemic malinga ndi momwe mulingo umasankhidwa molondola komanso mawonekedwe a jakisoni amawonekera.

Zomwe zimayambitsa pakubala

Amayi oyembekezera ayenera kusamala makamaka pakubaya insulin yamtundu uliwonse. Zotsatira zamaphunziro amakono azachipatala zimawonetsa kuti palibe zovuta zosagwirizana ndi kugwiritsa ntchito moyenera mankhwalawa.

Pa nthawi yomwe ali ndi pakati, odwala amayenera kuwunika kuchuluka kwa shuga m'magazi. Izi zikugwiranso ntchito pa matenda a shuga. Ndikofunikira kutsatira mosamalitsa malingaliro onse a dokotala, chifukwa mungafunike kusintha mlingo kutengera nthawi ya pakati.

Ngati mayi ali ndi matenda a shuga, akukonzekera kutenga pakati ndikutenga Humalog, ayenera kudziwitsa adotolo za izi. Pankhaniyi, muyenera kusintha chiwembu cha insulin.

Kugwiritsa ntchito mankhwala osokoneza bongo komanso mowa

Ndikofunikira kusamala makamaka kwa odwala omwe amagwiritsa ntchito mankhwala ena omwe amakhudza shuga. Mankhwala otsatirawa kuwonjezera shuga

• Mao zoletsa
• β-blockers
• Kukonzekera kwa sulfonamide.

Mankhwala monga clonidine, reserpine, β-blockers amaliza zizindikiro za shuga wamagazi. Mankhwala otsatirawa, m'malo mwake, amachepetsa mphamvu ya Humog:

• kulera kwamlomo
• glucocorticosteroid mankhwala,
• kukonzekera kwa chithokomiro,
• okodzetsa a mndandanda wa thiazide,
• tridclic antidepressants.

Mowa wambiri ndi insulin mankhwala kumabweretsa mphamvu ya zotsatira za hypoglycemic.

Mtengo, ndemanga ndi fanizo la mankhwala

Mankhwalawa amagulitsidwa kokha ndi mankhwala. Itha kugulidwa ku pharmacy wamba kapena pa intaneti. Mtengo wa mankhwala ochokera ku mtundu wa Humalog siwokwera kwambiri, aliyense amene ali ndi ndalama zambiri amatha kugula. Mtengo wazokonzekera ndi wa Humalog Remix 25 (3 ml, 5 pcs) - kuyambira 1790 mpaka 2050 rubles, ndi Humalog Remix 50 (3 ml, 5 ma PC) - kuyambira 1890 mpaka 2100 rubles.

Ndemanga ya anthu ambiri odwala matenda ashuga okhudza insulin Humalog yabwino. Pali ndemanga zambiri pa intaneti zokhudzana ndi kugwiritsa ntchito mankhwalawa, omwe amati ndizosavuta kugwiritsa ntchito, ndipo zimachitika mwachangu mokwanira.

Momwe mungagwiritsire ntchito Humalog?

Kwa mankhwala osokoneza bongo, cholembera cha syringe chapadera cha Quick Pen chimapezeka kuti chitha kugwiritsidwa ntchito mosavuta. Musanagwiritse ntchito, muyenera kuwerengera Maupangiri Ogwiritsira Ntchito.

Kathumba ka insulin kakufunika kuti kakulidwe pakati pa manja m'manja kuti kuyimitsidwa kukhale kopanda pake. Ngati mukupezeka tinthu tachilendo mkati mwake, mankhwalawa ndibwino kuti musagwiritse ntchito konse.

Kuti mulowe chida molondola, muyenera kutsatira malamulo ena.

Sambani manja anu mosamala ndikuwona malo omwe adzapange jekeseniyo. Kenako, kuchitira malowa ndi antiseptic.

Chotsani kapu yoteteza ku singano. Pambuyo pa izi, muyenera kukonza khungu.

Gawo lotsatira ndikuyika singano mobisalira molingana ndi malangizo. Pambuyo pochotsa singano, malowa ayenera kukanikizidwa osasenda.

Pa gawo lomaliza la njirayi, singano yomwe imagwiritsidwa ntchito imatsekedwa ndi chipewa, ndipo cholembera cha syringe chimatsekedwa ndi chipewa chapadera.

Malangizidwe ophatikizidwa ali ndi chidziwitso chokha chomwe dokotala yekha ndi amene angatchule mlingo woyenera wa mankhwalawa komanso kaimidwe ka insulin, poperekera shuga m'magazi a wodwalayo. Pambuyo pogula Humalog, malangizo ogwiritsira ntchito ayenera kuphunziridwa mosamala. Mmenemo mungaphunzire za malamulo operekera mankhwala:

• mahomoni opanga amaperekedwa pokhapokha, amakanizidwa kulowa nawo mkati,
• Kutentha kwa mankhwalawa panthawi ya makonzedwe sikuyenera kutsika kuposa kutentha kwa chipinda,
• jakisoni amapangidwa ntchafu, matako, phewa kapena pamimba,
• masamba ena obayira
• mukamapereka mankhwalawa, muyenera kuonetsetsa kuti singano sikuwonekera m'miyeso ya ziwiya,
• pambuyo insulin, malo jakisoni sangathe kuzunzika.

Musanagwiritse ntchito, kusakaniza kuyenera kugwedezeka.

Alumali moyo wa mankhwala ndi zaka zitatu. Nthawi iyi ikatha, kugwiritsa ntchito kake kumaletsedwa. Mankhwalawa amasungidwa pamtunda kuchokera 2 mpaka 8 madigiri popanda mwayi wowunika.

Mankhwala omwe amagwiritsidwa ntchito amasungidwa pa kutentha osaposa madigiri 30 kwa masiku 28.

Bukuli likufunikira kuwerengera kuchuluka kwa mankhwalawa payekha payekha kuti athandizane ndi endocrinologist. Zimatengera momwe wodwalayo alili, kulemera kwake komanso zinthu zina. Mankhwalawa amatha kuthandizidwa musanadye chakudya komanso nthawi yomweyo (ngati pakufunika kutero). Popeza uyu ndiwothandizirana naye pang'ono, mphamvu yake imadziwoneka yokha mokwanira.

Kuti mulowe mankhwalawa, muyenera cholembera chapadera cha insulin. Nthawi ina kale, panali syringe yogulitsa - cholembera cha insulin pansi pa dzina lomweli. Koma pakadali pano zalekedwa. M'malo mwake, zolembera za 3 ml ya Humapen Savvio insulin Humapen zinagulitsidwa.

Kugwiritsa ntchito chipangizo chotere, mutha kubaya kumatanthauza Humulin, Humalog Mikst, Humalog, etc. Muli ndi zida zowerengera makina, omwe amathandizira kwambiri kugwiritsa ntchito mankhwalawa komanso kuyang'anira. Kuchuluka kwa cartridge ndi 3 ml.

Humalog imangoyambika pa gawo lomweli. Njira yobweretsera mankhwalawa m'thupi ndi yachilendo, yamitsempha, ndipo nthawi zina kudzera m'mitsempha. Kuwongolera kwapakati pa Humalog kumatheka kokha kuchipatala, chifukwa kunyumba njira yanjirayi imalumikizidwa ndi zoopsa zina. Ngati Humalog ikupezeka muma cartridge, ndiye kuti iyenera kuyendetsedwa kokha.

Ikani Humalog musanadye. Ndikofunika kuti muzisunga nthawi yoyambira: mphindi 5 - 15 musanadye. Pafupipafupi jakisoni amachokera 4 mpaka 6 pa tsiku. Ngati wodwala amapereka insulin yayitali, ndiye kuti Humalog imagwiritsidwa ntchito katatu patsiku.

Ndi dokotala yekhayo amene amapereka mlingo woyenera wa mankhwala otere. Zowonjezera zake ndizovomerezeka pazokha.

Amaloledwa kuphatikiza ndi ma fanizo ena a insulin ya anthu, ngati kusakanikirana uku kuli mu syringe. Mwachitsanzo, imatha kusakanikirana ndi insulin yowonjezera.

Komabe, munthu ayenera kukumbukira kuti Humalog iyenera kulembedwanso koyamba. Atangosakaniza zinthu zotere, jakisoni amayenera kupangidwa.

Ngati wodwala agwiritsa ntchito cartridge, ndiye kuti safunika kuwonjezera mtundu wina wa insulin. Kusakaniza kwa Humalog 25 kumakhala ndi malangizo ofanana ndi mitundu ina ya mahomoni awa.

Contraindication

Mankhwala a Humalog Remix 25 ndi Humalog Mix 50 ali ndi zotsutsana ziwiri zokha - uwu ndi mkhalidwe wa hypoglycemia komanso chidwi chamunthu pazinthu zomwe zili pokonzekera.

- shuga mellitus mwa akulu ndi ana, omwe amafunikira chithandizo cha insulin kuti akhalebe ndi shuga.

Mukamathandizidwa ndi Humalog, mavuto ena amatha kuchitika. Ndikofunikira kuti muziphunzira mosamalitsa ndikusamala za thanzi lanu pakapita nthawi. Chifukwa chake, Humalog imatha kuyambitsa zotsatirazi zosafunikira m'thupi la munthu:

1. Kutukwana.
2. Khungu pakhungu.
3. Kuchuluka kwa mtima.
4. Kutentha.
5. Madigiriulo ena osokoneza kugona amatha.
6. Kusokonezeka kwa chikumbumtima, ndipo nthawi zina kutayika kwathunthu, komwe kumalumikizidwa ndi kuchuluka kwa hypoglycemia.
7. Zowonongeka zowoneka bwino, zomwe zimapezeka pazowonongeka.
8. Zotsatira zoyipa (zosowa kwambiri).
9. Kuchepetsa kuchuluka kwa mafuta pamafuta ochulukirapo.

Mankhwala osokoneza bongo amapezeka pomwe wodwalayo amawerengera molakwika. Zizindikiro zazikuluzikulu za bongo ndi kufooka, nseru, mutu, kuchuluka kwa mtima, kuzindikira. Chithandizo cha izi ndi chimodzimodzi ndi hypoglycemia. Itha kuimitsidwa msanga pomwa chakudya chamafuta othamanga kapena mwa kukhazikitsa njira ya glucose (kuchipatala).

Milandu yambiri ya hypoglycemia imayimitsidwa ndi kutsekeka kapena kupindika kwa glucagon. Ngati palibe chochita ndi glucagon, ndiye kuti dextrose imayambitsidwa chimodzimodzi. Chidziwitso cha wodwalayo chikadzabweranso, amafunikira kupatsidwa chakudya cham'thupi. Ngati zizindikiro za mankhwala osokoneza bongo zibwerezedwanso pafupipafupi, ndiye kuti kusintha kwa zakudya ndi kuwonjezeka kwa chakudya kumatha.

Humalog insulini mu cholembera

Humalog ndi mankhwala osokoneza bongo omwe ali ndi insulin yachilengedwe yopangidwa ndi thupi la munthu. DNA ndi njira yosinthira. Chodabwitsa ndichakuti Humalog imasintha kapangidwe ka amino acid m'maketeni a insulin. Mankhwala amawongolera kagayidwe kakang'ono ka shuga m'thupi. Zimatengera mankhwala okhala ndi zotsatira za anabolic.

Kubayidwira mankhwala kumathandizira kukulitsa kuchuluka kwa glycerol, acid acid ndi glocogen m'thupi. Imathandizira kuthamangitsa kaphatikizidwe ka mapuloteni. Njira yothetsera kumwa kwa amino acid imathandizira, zomwe zimapangitsa kuchepa kwa ketogeneis, glucogenogeneis, lipolysis, glycogenolysis, mapuloteni catabolism. Mankhwalawa ali ndi kanthawi kochepa.

Gawo lalikulu la Humalog ndi insulin lispro. Komanso, kapangidwe kameneka kamathandizidwa ndi oyambitsa zochitika zapakhomo. Palinso mitundu yosiyanasiyana ya mankhwalawa - Humalogmix 25, 50 ndi 100. Kusiyanitsa kwake kwakukulu ndi kukhalapo kwa Hagedorn mu proitamin yosalowerera, yomwe imachepetsa mphamvu ya insulin.

Manambala 25, 50 ndi 100 akuwonetsa kuchuluka kwa NPH pamankhwala. Humalogmix yowonjezereka yomwe imakhala ndi kulowererapo kwa Hagedorn, m'pamenenso mankhwala omwe angagwiridwe ntchito amatha kuchita. Chifukwa chake, mutha kuchepetsa kufunika kwa jakisoni yambiri, yopangidwira tsiku limodzi. Kugwiritsa ntchito mankhwalawa kumathandizira kuchiza matenda okoma komanso kumapangitsa moyo kukhala wosavuta.

Monga mankhwala aliwonse a Humalogmix 25, 50 ndi 100 ali ndi zovuta.

Mankhwala salola kupanga chiwonetsero chokwanira pa magazi a shuga.

Palinso milandu yokhudzana ndi chifuwa cha mankhwalawa ndi zovuta zina. Madokotala nthawi zambiri amapereka insulin Humalog mu mawonekedwe oyera m'malo osakanikirana, chifukwa mankhwalawa a NPH 25, 50 ndi 100 angayambitse zovuta za matenda ashuga, nthawi zambiri amatha kudwala. Ndiwothandiza kwambiri kugwiritsa ntchito mitundu komanso mankhwalawa pochiza odwala okalamba omwe ali ndi matenda ashuga.

Nthawi zambiri, kusankha kwa mankhwala oterowo kumachitika chifukwa chakuyembekezerera kwakanthawi kochepa kwa odwala komanso kukula kwa demokalase. Pazigawo zotsala za odwala, Humalog mu mawonekedwe ake oyera amalimbikitsidwa.

Kuzindikira kwa shuga - ingomwani tsiku lililonse.

Kutulutsa Fomu

Mankhwalawa amapezeka ngati kuyimitsidwa kwa jakisoni pansi pa khungu. The yogwira ndi insulin lispro 100 IU.

Zowonjezera zinalembedwe:

• 1.76 mg metacresol,
• 0,80 mg wa phenol madzi,
• 16 mg a glycerol (glycerol),
• 0,28 mg proitamin sulfate,
• 3.78 mg wa sodium hydrogen phosphate,
• 25 mcg wa zinc oxide,
• 10% hydrochloric acid solution,
• Kufikira 1 ml ya madzi a jakisoni.

Thupi limayera ndi utoto, wokhoza kufalikira. Zotsatira zake zimakhala zoyera komanso zamadzimadzi zomveka zomwe zimasonkhana pamwamba pa mpweya. Kuti mupeze jakisoni, ndikofunikira kusakaniza madzi omwe amapangidwa ndi matope mwa kugwedeza mopepuka ma ampoules. Humalog ikukhudzana ndi njira zophatikiza ma insulin achilengedwe ndi nthawi yayitali komanso yochepa kuchitira.

Osakaniza 50 quicpen ndi osakaniza achilengedwe ochita mwachangu insulin (insulin solution lispro 50%) ndi sing'anga kanthu (proitamin kuyimitsidwa insulin lispro 50%).

Cholinga cha chinthu ichi ndikuwongolera kagayidwe kachakudya ka shuga m'thupi. Zochita za Anabolic komanso zotsutsa-catabolic m'maselo osiyanasiyana a thupi zimadziwikanso.

Lizpro ndi insulin, yomwe imafanananso ndi mahomoni opangidwa m'thupi la munthu, ngakhale kuchepa kwathunthu kwa shuga mumagazi kumachitika mwachangu, koma zotsatira zake zimakhala zochepa. Kumwirira kwathunthu m'magazi ndikuyamba kwa zomwe zikuyembekezeka kuchitazi mwachindunji zimatengera zifukwa zingapo:

• Masamba a jekeseni (kulowetsa pamimba, m'chiuno, matako),
• Mlingo (kuchuluka kwa insulini),
• kayendedwe ka magazi
• kutentha kwa thupi kwa wodwalayo
• kulimbitsa thupi.

Mutapanga jakisoni, mphamvu ya mankhwalawa imayamba pakatha mphindi 15 zotsatira. Nthawi zambiri, kuyimitsidwa kumayikidwa pakhungu pakatsala mphindi zochepa chakudya chisanachitike, zomwe zimathandiza kuti pasapezeke shuga. Poyerekeza, mphamvu ya lyspro insulin ingafaniziridwe ndi zomwe amachita ndi insulin ya munthu - isophan, yemwe zochita zake zimatha mpaka maola 15.