Chithandizo cha Pancreatic: Kuwunika kwa Mankhwala Othandiza

Ululu womwe umagwera munthu akakumana ndi mavuto am'modzi mwa ziwalo za endocrine sulephera. Ndikotheka kuchepetsa komanso kupatsanso mankhwala othandizira mothandizidwa ndi mankhwala osiyanasiyana. Koma chithandizo cha kapamba ndi mankhwala iyenera kuchitika poganizira zomwe zimayambitsa zovuta zaumoyo. Kutengera izi, mphamvu ya mankhwalawo ndi yosiyana.

Mankhwala amatanthauza kukonzekera kwa enzymatic komwe kumagwiritsidwa ntchito kutsimikizira zikondwerero zina zonse. Pakakhala kuchuluka kokwanira kwa ma enzymenti omwe amapangidwa ndi iye m'magazi, thupi limaleka kupanga kwawo, ndipo iyi ndi imodzi mwazinthu zothandizira.

Mankhwala amagwiritsidwa ntchito pancreatic insufficiency, kusokonezeka kwa m'mimba, chikhodzodzo, chiwindi, matumbo. Komanso, mankhwalawa amatha kugwiritsidwa ntchito pochiza matenda osokoneza bongo, cystic fibrosis, matenda osachiritsika opuwala. Zothandiza Zimathandizira kukonza mgaya.

Ndikotheka kuchita mankhwalawa omwe kapamba, m'mimba, ndi ziwalo zina zam'mimba zimafunikira kudzera mu mawonekedwe a mankhwalawa, monga mapiritsi okhala ndi mankhwala.

Enzistal ili ndi zinthu zingapo zogwira ntchito:

• Pancreatin
• Pagululi,
• Bovine bile Tingafinye.

Mndandanda wazinthu zothandizira ndi monga:

• Colloidal silicon dioxide,
• Magnesium wakuba,
• Lactose Monohydrate.

Phale lomwe lili ndi:

Ngati kapamba amapweteka kapena ngati pakufunika thandizo la chakudya cham'mimba, komanso kuchiza matenda osiyanasiyana, mankhwalawa amagwiritsidwa ntchito motere:

• Ana opitirira zaka zopitilira 6 ndi achinyamata amapatsidwa piritsi limodzi kawiri (kupitilizidwa katatu) patsiku. Odwala omwe ali m'gulu lino ayenera kutumizidwa ndi adokotala okha.
• Akuluakulu amakulimbikitsidwa kumwa mankhwalawa kuchuluka kwa mapiritsi awiri katatu / tsiku. Pakuganiza kwa dotolo, muyezo utha kuchuluka, koma sizingachitike mwaokha.

Kutalika Kovomerezeka Enzistala atha kukhala masiku angapo kapena miyezi ingapo. Odwala nthawi zina amagwiritsa ntchito mankhwalawa kwa zaka zingapo, ngati pakufunika kupitiliza chithandizo chamankhwala.

Pali zotsutsana pa kugwiritsa ntchito mankhwala omwe amathandizira kapamba:

• Hepatitis
• Matenda kapamba mu mawonekedwe pachimake
• Kulephera kwa chiwindi
• Makina jaundice,
• Hyperbilirubinemia,
• Kutsekeka kwamkati,
• Cholelithiasis,
• Hepatic precoma (kapena chikomokere).

Gentamicin

EMankhwalawa ndi anti-spectrum antiotic, ndipo amagwiritsidwa ntchito, pakati, pochizira kapamba. Kuchotsa kutupa kumatsimikiziridwa ndikuwonongeka kwa tizilombo toyambitsa matenda omwe amayambitsa njirayi.

Mankhwalawa amalepheretsa kuchulukana kwa njira zotupa, chifukwa chake amagwiritsidwa ntchito onse pochotsa ziphuphu, m'mimba, ziwalo zina zam'mimba, komanso ziwalo zina. Njira yothetsera jakisoni imagwiritsidwa ntchito.

Gawo lalikulu la mankhwalawa ndi gentamicin sulfate.

Pamndandanda wazinthu zothandizira pazomwe mungagwiritse ntchito mankhwalawa:

• Methylhydroxybenzoate,
• Edetate disodium,
• Sodium bisulfate
• Propylene glycol.

Mlingo wa mankhwalawa umatengera matenda omwe amakhudza kapamba, komanso zaka za wodwalayo.

• Makanda obadwa kumene amasankhidwa 2-5 mg / 1 kg ya kulemera kwa mwana pafupipafupi jakisoni kawiri / tsiku. Mlingo womwewo, mankhwalawa amalembedwa kwa ana osakwana zaka 2, koma jekeseni wobadwa katatu kapena tsiku,
• Ana opitirira zaka 2 ndi akulu amalimbikitsidwa kugwiritsa ntchito Mlingo wa 1-1.7 mg / 1 kg wa wodwala. Pankhaniyi, zosaposa 3-5 mg / 1 kg za wodwala zimayenera kuperekedwa patsiku. Pafupipafupi jakisoni ndi nthawi 2-4 / tsiku.

Kuchiza ndi mankhwalawa kuti muchepetse kutupa ndikuchotsa mavuto ena kumatenga pafupifupi sabata.

Zoyipa zogwiritsidwa ntchito ndi mankhwalawa ndi:

• Kusagwirizana ndi zinthu za mankhwala,
• Kukhalapo kwa mitsempha yamitsempha yamagetsi,
• Matenda a impso,
• Mimba, kuyamwa,
• Uremia
• Kusagwirizana ndi maantibayotiki omwe ali m'gulu la aminoglycosides.

Mankhwala ndi a gulu la maantacid, chithandizo cha kapamba chimachitika pogwiritsa ntchito mankhwalawa monga mapiritsi. Mankhwalawa amatha kusokoneza ma asidi, kuchepetsa kupsa mtima kwa chilengedwe. Kuphatikiza apo, mankhwalawa amaletsa kulowa kwake mu duodenum. Chidacho chimalimbikitsa kupanga ma pancreatic enzymes, komanso kuyambitsa kwawo.

Mankhwalawa ali ndi kuthekanso kwa adsorb bile acid, pepsin. Chida chimagwiritsidwa ntchito pochiza matenda amtumbo. Itha kutengedwa ngati m'mimba apweteka, kapamba chifukwa chosowa ma enzymes.

Zomwe amapangira mankhwalawa zimaphatikizapo zinthu monga zinthu zazikulu:

• Magnesium hydroxide,
• Aluminium hydroxide.

Muli zamankhwala ndi zina zowonjezera:

• Magnesium wakuba,
• Tsabola wa Peppermint
• Wowuma chimanga
• Sodium saccharin
• Sorbitol
• Kubwezeretsa
• Mannitolum.

Pankhani yamomwe mungamwe mapiritsi kuti muchiritse kapamba, m'mimba, ziyenera kuthetsedwa.

Malangizo omwe amamwa mankhwalawa amapereka malangizo:

• Pofuna kupewa, muyenera kumwa piritsi limodzi la ola limodzi la ola musanamwe mankhwala ena omwe kapamba amamugwirira.
• Ana azaka zapakati pa 10 ndi 10 akuyenera kugwiritsa ntchito piritsi la ½-1 kawiri / tsiku,
• Ana azaka zopitilira 15, komanso achikulire, amalangizidwa kuti azimwa mapiritsi ambiri a ma PC. kanayi / tsiku 1 itatha chakudya. Mutha kumwa piritsi limodzi usiku ngati mukufuna kuchotsa kutentha kwamtima, kupweteka kwa epigastrium, kusapeza bwino m'mimba, matumbo.

Pali zingapo zotsutsana pamankhwala omwe mumamwa:

• Hypersensitivity pamagawo a mankhwala,
• Fructose ziwengo,
• Matenda a Alzheimer's
• Kuperewera kwa isomaltase, sucrose,
• Matenda a impso,
• Mimba
• Hypophosphatemia.

Gwiritsani ntchito mosamala Zowonongera uku mukuyamwa.

Chidacho chimagwiritsidwa ntchito polimbikitsa kupanga ndi kuyambitsa kwa ma pancreatic enzymes. Mankhwala amagwiritsidwa ntchito kufalikira kwa kapamba, omwe amathandiza kwambiri masiku ochepa kuyambira chiyambi cha matenda, komanso kupewa pakanthawi ya ntchito.

Mankhwala amagwiritsidwa ntchito ngati mankhwala a lyophilisate a jakisoni kapena ma dontho.

Chofunikira kwambiri pa mankhwalawa ndi aprotinin. Isotonic sodium chloride imagwiritsidwa ntchito ngati zosungunulira. Chowonjezera china cha lyophilisate ndi mannitol.

Kodi mankhwalawa amayenera kugwiritsidwa ntchito molingana ndi momwe amagwiritsidwira ntchito:

• Pankhani ya pancreatitis pachimake, mankhwalawa amayamba kutumikiridwa kudzera m'mitsempha ya 200,000 mpaka 300,000 ATPE. Kenako, dontho lokha ndi mankhwalawa lingathe kutumizidwa. Mwanjira imeneyi, mankhwalawa amathanso kutumikiridwa,
• Pofuna kupewa pambuyo pa opaleshoni ya kapamba, jekeseni wothandizidwa ndi wothandizila kuchuluka kwa 200,000 ATPE, womwe ndi mulingo wa tsiku ndi tsiku wa mankhwalawa.

Kutalika kwa mankhwalawa kumatengera mphamvu zakukula kwa mkhalidwe wa wodwalayo.

Osagwiritsa ntchito "Contrical" pazithandizo zotere:

• Mimba ine trimester,
• Kusalolera ku madera "Contrikala".

Chidacho chimatanthauzira ku mahomoni, ndipo chimagwiritsidwa ntchito kupondaponda kupanga michere m'mimba, kapamba. Tiyenera kukumbukira kuti mankhwalawa amathandizira kuchepetsa kupezeka kwa magazi kwa thupi, chifukwa chake, amawerengedwa mosamala kwambiri, pokhapokha ngati pakufunika. Mndandanda wazomwe ungagwiritse ntchito mankhwalawa umaphatikizapo pancreatitis ya pachimake.

Amagwiritsidwa ntchito jakisoni ndi ma dontho ngati njira yankho. Chofunikira kwambiri pa mankhwalawa ndi octreotide, ndipo mndandanda wazinthu zothandizira zimaphatikizapo madzi oyeretsedwa ndi sodium chloride.

Polimbana ndi pancreatitis pachimake, mankhwalawa amathandizira kuchuluka kwa 100 μg katatu / tsiku mu mawonekedwe a dontho. Ngati mankhwalawa amaperekedwa kudzera mu mtsempha wa magazi, mlingo wa tsiku ndi tsiku ungakhale 1200 mcg.

Kutalika kwa ntchito "Octreotide" Nthawi zambiri masiku 5, koma kutengera momwe wodwala alili, nthawizi zimatha kukhala zosiyanasiyana.

Izi sizigwiritsidwa ntchito pazochitika zotsatirazi:

• Wodwala wosakwana zaka 18
• Hypersensitivity ya wodwala kumagawo "Octreotide."

Kusamala poika ndalama kuyenera kuwonetsedwa ngati wodwala ali ndi matenda a shuga, cholelithiasis. Izi zikugwiranso ntchito kwa odwala omwe ali ndi pakati.

Kudzipangira nokha mankhwala kumatha kukulitsa mkhalidwe wa wodwalayo, chifukwa chake, kulumikizana ndi dokotala ndikofunikira, ndipo pokhapokha mutatha kuyamba kulandira mankhwala.