Momwe mungamwe (kumwa) mapiritsi a Reduxin Met

Mlingo woyambira wothandiza ndi piritsi limodzi lokhala ndi 850 mg ya metformin ndi 1 kapisozi yokhala ndi 10 mg ya sibutramine. Mapiritsi ndi makapisozi amayenera kumwa m'mawa nthawi yomweyo, osafuna kutafuna ndi kumwa madzi ambiri (kapu imodzi yamadzi) kuphatikiza ndi chakudya.

Muyenera kuwunika momwe masinthidwe amasinthidwe a shuga m'magazi ndi mphamvu ya kuwonda. Ngati patatha sabata limodzi kapena awiri mulingo woyenera wamagazi m'magazi sukwaniritsidwa, mlingo wa metformin uyenera kuwonjezeka mpaka mapiritsi awiri. Mulingo woyenera wokonzanso wa metformin ndi 1700 mg patsiku. Mlingo wapamwamba tsiku lililonse wa metformin ndi 2550 mg. Kuti muchepetse mavuto kuchokera m'matumbo, gawo la metformin la tsiku ndi tsiku lingagawidwe pawiri. Mwachitsanzo, imwani piritsi 1 m'mawa ndi piritsi 1 yamadzulo.

Ngati mkati mwa masabata 4 kuyambira chiyambi cha chithandizo, kuchepa kwa thupi kwa 2 kg sikunatheke, ndiye kuti mlingo wa sibutramine ukuwonjezeka mpaka 15 mg / tsiku. Kuchiza ndi Reduxin ® Met sikuyenera kupitilira miyezi yoposa 3 kwa odwala omwe satsatira bwino chithandizo, i.e. omwe mkati mwa miyezi 3 ya chithandizo sangathe kukwaniritsa kuchepa kwa 5% kuchokera ku chisonyezo choyambirira. Kuchiza sikuyenera kupitilizidwa ngati, pogwiritsa ntchito mankhwala ena pambuyo pakuchepa kwa thupi, wodwalayo amawonjezeranso 3 kg kapena kuposerapo thupi. Kutalika kwa mankhwalawa sikuyenera kupitilira chaka chimodzi, chifukwa nthawi yayitali mukamamwa mankhwala a sibutramine, kugwiritsa ntchito bwino komanso chitetezo sichimapezeka.

Kuchiza ndi Reduxin® Met kuyenera kuchitika molumikizana ndi kadyedwe ndikuchita masewera olimbitsa thupi moyang'aniridwa ndi adokotala odziwa ntchito yothana ndi kunenepa kwambiri.

Kupanga ndi mafomu omasulira

Mankhwalawa amapezeka m'magawo awiri (mapiritsi + makapisozi).

Kuphatikizidwa kwa mapiritsiwa kumaphatikizapo 850 mg ya yogwira mankhwala yoyimiriridwa ndi metformin hydrochloride. Zinthu zina zilipo:

Povidone
Madzi okonzedwa
Stearic Acid Mg
MCC.

Chikuto chilichonse chimakhala ndi magawo awiri - MCC ndi sibutramine hydrochloride monohydrate mu 158,5 mg ndi 10 mg. Zowonjezereka zimaperekedwa:

Titanium dioxide
Colour jambo
Zopangira zamagalamu.

Chigawo chachiwiri chimakhala ndi miyala yofanana ndi yoyamba. Makapisozi amaphatikizapo 15 mg ya sibutramine hydrochloride monohydrate, komanso 153,5 mg wa gawo lachiwiri - MCC. Zowonjezera za makapisozi: Ti dioxide, gelatin, utoto wabuluu.

Mapiritsi oyera okhala ndi zowopsa amayikidwa mu chithuza chamtundu wa ma PC 10., Mkati mwa paketiyo muli matuza awiri kapena 6.

Makapisozi amtundu wamtambo wabuluu komanso wabuluu wokhala ndi mawonekedwe oyera a powdery okhala ndi mthunzi wa kirimu amayikidwa mu chithuza cha ma PC 10., paketi ili ndi matuza 1 kapena 3.

Katimuyo akhoza kukhala ndi mapiritsi 20 kapena 60. ndi 10 kapena 30 zisoti.

Kuchiritsa katundu

Reduxin Met ndi amodzi mwa mankhwala omwe amagwiritsidwa ntchito pofuna kuchiza matenda oyambira kunenepa kwambiri, omwe adayamba chifukwa cha matenda a shuga a mtundu wachiwiri omwe amapita patsogolo. Ndikulimbikitsidwa kumwa mankhwalawa m'mawa ndi chakudya china chowonjezera. Mkati mwake mumakhala ma metformin m'mapiritsi, komanso MCC yokhala ndi sibutramine m'mapiritsi.

Mtengo: kuchokera 655 mpaka 4007 rub.

Metformin imafunika kuti achepetse kuchuluka kwa hypreglycemia. Mukamamwa mankhwalawa, kukula kwa hypoglycemia sikuwonetsedwa poyerekeza ndi mankhwala omwewo. Pankhaniyi, palibe kukondoweza kwa kupanga insulini, njira yolembera mafuta osakanikirana imayimitsidwa, ndipo njira yogwiritsira ntchito shuga ipangika. Kuphatikiza apo, chizindikiro cha plasma cha cholesterol chimachepa. Chifukwa cha kudya kwa metformin m'thupi, ndizotheka kukhazikika pamtunda ndikuthamanga njira yochepetsera.

Sibutramine amalimbikitsa kutsegula kwa ma serotonin receptors, chifukwa cha izi ndizotheka kumva mwachangu zonse mukamadya.

Ndizofunikanso kudziwa kuti kupanga mafuta ochulukirachulukira kukuwonjezereka, zotsatira zake zamafuta a bulauni zimawonekera, zomwe zimatenga gawo lake pantchito imeneyi. Mukamagwiritsa ntchito mankhwala opangidwa ndi sibutramine, kuchepa thupi komanso kuchuluka kwakanthawi kumawonedwa. Wodwalayo amapita pang'onopang'ono kutenga magawo ang'onoang'ono.

Ma cellulose mu mawonekedwe a microcrystalline amachita ngati enterosorbent. Chifukwa cha malo ake enieni, njira yochotsa zinthu zapoizoni ndi zinthu zowola zomwe zimasokoneza magwiridwe antchito am'mimba zimathandizira. Pamodzi ndi metformin, komanso sibutramine, imagwiritsidwa ntchito kuchepetsa thupi mopitirira muyeso, popeza omwe amasiya mankhwalawa amathandizira zotsatira za wina ndi mnzake, zomwe zimakhudza kutha kwa mankhwalawa.

Malangizo ogwiritsira ntchito

Choyamba muyenera kumwa mankhwalawa 1 tabu. ndi 1 zisoti. Maola 24 panthawi, pamene kuli kofunikira kumwa mankhwala okhala ndi madzi okwanira. M'tsogolomu, muyenera kuwongolera kunenepa. Ngati 14 masiku. Mankhwala, kuchepa kwakukulu kwa thupi sikulembedwa kapena mphamvu zake ndizofooka kwambiri, kuthekera kwa kuchuluka kochulukirachulukirapo sikudziwika.

Momwe mungamwere mankhwala

Ndikosatheka kunena mtundu wamtundu wanji womwe ungayambitse kumwa mankhwalawo. Pali mwayi wokhala ndi vuto loipa ngati simungatsatire zomwe dokotala wakhazikitsa. Ngati mumwa mankhwalawo molondola, ndiye kuti mavuto omwe akuwonekera sadzaonekera. Sikoyenera kuyamba mankhwala achire mwa kutenga mankhwala ochulukirapo, kutenga chipewa chimodzi ndi njira yabwino kwambiri. ndi 1 tabu. patsiku. Pofuna kupewa kuphwanya mayendedwe am'mimba, kuchuluka kwa magawo a mankhwalawa sikuyenera kukhala kwakukulu kuposa ma PC atatu., Mankhwalawa amayenera kuledzera mogwirizana ndi nthawi.

Contraindication ndi Kusamala

Sikulimbikitsidwa kumwa mapiritsi ndi makapisozi ndi:

Okalamba (wodwala woposa zaka 65)
Zizindikiro za matenda opatsirana omwe amayambitsidwa ndi kupuma kwa dongosolo la kupuma
Kuthamanga kwa magazi
Matenda aimpso
Kuzindikira Glaucoma
Mimba, GV
Kupezeka kwa anorexia amanosa
Kuzindikira matenda a Gilles de la Tourette.

Ndikofunika kudziwa kuti mankhwalawa sagwiritsidwa ntchito ngati ana.

Kuchita mankhwala osokoneza bongo

Mankhwala okhala ndi iodine ya Radiocontrast sayenera kumwedwa panthawi ya mankhwala, chifukwa pamaso pa kusokonezeka kwa dongosolo la impso mwa anthu omwe ali ndi matenda ashuga, mwayi wa lactic acidosis ukuwonjezeka. Metformin idzafunika kumaliza masiku awiri. isanachitike mayeso a X-ray ogwiritsa ntchito ayodini wokhala ndi radiopaque kukonzekera. Kugwiritsanso ntchito mankhwalawa ndikotheka patatha masiku awiri. ndi chitsimikiziro chachilendo chantchito.

Ndikofunikira kupatula kumwa mowa pakumwa.

Mosamala, ndikofunikira kumwa nthawi yomweyo GCS, Danazole, Chlorpromazine, okodzetsa, komanso beta₂-adrenomimetics, zoletsa za ACE.

Sizikulamulidwa kuti pakhale hypoglycemia pamene akumwa mankhwala a insulin, kukonzekera kwa salicylate, acarbose, mankhwala ozunguza bongo wa sulfylurea.

Mankhwala a Nifidepine ndi cationic amatha kupangitsa kuchuluka kwa metformin kowopsa.

Ma inhibitors a microsomal oxidation process angayambitse kuchuluka kwa plasma of sibutramine metabolites. Kupititsa patsogolo kwa kagayidwe ka sibutramine kumawonedwa ndikugwiritsa ntchito munthawi yomweyo Dexamethasone, Rifampicin, othandizira antibacterial ochokera ku gulu la macrolide, phenobarbital, Phenytoin, komanso Carbamazepine.

Mukamamwa mankhwala omwe amachulukitsa kuchuluka kwa plotma ya serotonin, mankhwala ochizira migraine, ma paninkiller amphamvu, kukula kwa serotonin syndrome sikutsutsidwa.

Pogwiritsa ntchito munthawi yomweyo mankhwala omwe amakhudza hemostasis kapena kupatsidwa zinthu za m'magazi, chiopsezo chotaya magazi chitha kuchuluka.

Pankhani kutenga ndalama zochokera ephedrine ndi pseudoephedrine, chisamaliro chapadera chiyenera kutengedwa.

Sichikulimbikitsidwa kuphatikiza kumwa mankhwalawo ndi mankhwala omwe amakhudza ubongo.

Zotsatira zoyipa ndi bongo

Poyerekeza ndi momwe ntchito mankhwalawa imagwiritsidwira ntchito:

Zizindikiro za lactic acidosis
Kusokoneza kwam'mimba
Kuzindikira kwa kukoma
Maonekedwe a totupa pakhungu
Kudumpha kowopsa m'mwazi
Tachycardia akuukira
Thukuta kwambiri
Kukula kwa zopweteka
Kupweteka kwa epigastric
Kukula kwa malingaliro ofuna kudzipha
Kutsegula magazi muchiberekero
Mavuto amisala
Kusokonezeka tulo
The zimachitika chiwindi matenda.

Mukamamwa Mlingo waukulu wa metformin, lactic acidosis imatha kuchitika. Pankhani yogwiritsa ntchito mankhwala osokoneza bongo a sibutramine, kuwonjezereka kwa zizindikiro za mbali kumawonedwa. Ndi mawonekedwe owonetsa mawonekedwe osayenera, ndikofunikira kumaliza mankhwalawo mwachangu.

Ngati ndi kotheka, Reduxine akhoza kulembedwa. Popereka Reduxin ndi Reduxin Met, si aliyense amene amadziwa kusiyana kwake. Kusiyana kwakukulu ndiko kupezeka kwa piritsi lomaliza ndi metformin.

Mtengo kuyambira 470 mpaka 1835 rubles.

Mankhwala omwe amalepheretsa m'mimba lipases. Ntchito mankhwalawa onenepa. Gawo lalikulu ndi orlistat. Pa mankhwala, tikulimbikitsidwa kutsatira zakudya. Mankhwalawa ali ngati mapiritsi.

Ubwino:

Ndi kuvomereza pafupipafupi, kagayidwe kachakudya ka metabolism kamasinthasintha
Njira yoyenera yogwiritsira ntchito
Zimapezeka popanda mankhwala.

Chuma:

Zitha kuyambitsa chisangalalo
Sichikuperekedwa kwa nephrolithiasis
Simalimbikitsidwa kuti agwiritsidwe ntchito munthawi yomweyo ndi sodium levothyroxine.

The mankhwala Reduxin

Kuti mudziwe kufunika kokatenga mankhwala enaake kuti muchepetse kunenepa, muyenera kudziwa zomwe zili mu kapangidwe kake. Reduxine amapezeka m'mitundu iwiri: makapisozi ndi mapiritsi. Alinso ndimayendedwe ofanana ndipo mutha kusankha njira ina iliyonse yolandirira kapena kugwiritsa ntchito nthawi imodzi. Kupanga kwa Reduxine m'mitundu yonseyi ndikosavuta, koma kumasintha kwambiri.

Fomu ya Met, ngati analogue ya Reduxin-Goldline, ili ndi sibutramine mu kapangidwe kake. Mkati mwa kapisozi umodzi, zomwe zimapezeka zimafikira mu 15 mg. Izi, zomwe zimakhala m'mankhwala omwe amathandizira kuchepetsa thupi, zimapangitsa kuti muzimva kukomoka kwa nthawi yayitali, sizimalola munthu kudya mopitirira muyeso. Reduxine, makapisozi ake omwe amakhala osalala bwino kunja kwake ndi ufa wabwino mkati, amapezeka m'matupa a zidutswa za makatoni 30. Chipolopolocho chimapangidwa pamaziko a gelatin, motero chimasungunuka bwino pambuyo pakulowetsa.

Reduxin amatengedwa osati kokha kuti muchepetse thupi, komanso kuti athane ndi matenda a shuga, omwe nthawi zambiri amayamba chifukwa cha kunenepa kwambiri. Chithandizo chili ndi chinthu chotchedwa metformin. Iyenera kuchitika mosamala, kutsatira mosamalitsa malangizo. Reduxin wa mankhwala, mapiritsi omwe ali ndi 850 mg wa metformin, amagulitsidwa kuzipatala mumapaketi a zidutswa 10 kapena 60. Ngati pazifukwa zina mwaganiza zoyamba kumwa nokha, kumbukirani kuti mlingo wa tsiku ndi tsiku wa chinthucho suyenera kupitirira 2550 mg.

Malangizo Reduxin Met

Mankhwala aliwonse ayenera kumwedwa molingana ndi chiwembu china, kuti chitha kugwira ntchito komanso osavulaza thupi. Malangizo Reduxine Met akuti poyamba muyenera kumwa mankhwalawa 1 kapiritsi ndi piritsi 1 patsiku, osambitsidwa ndi madzi. Kupitilira apo, ndikofunikira kuchita zowongolera ndipo ngati, patatha milungu iwiri, pali mphamvu zopanda mphamvu kapena sizikupezeka, ndiye kuti kuwonjezeka kwa kawiri ndikotheka.

Zizindikiro zogwiritsidwa ntchito

Sibutramine yochepetsa thupi ndi chinthu china ngati panacea, chifukwa chimaletsa kudya kwambiri, kuchepetsa chilakolako chofuna kudya. Komabe, zikuwonetsa kugwiritsidwa ntchito kwa Reduxine Met ndi magawo oyambira a kunenepa kwambiri, pomwe zimakhudza kwambiri vutoli. Kuphatikiza apo, ngati kulemera kwambiri kwa thupi, komwe kumatha kugonjetsedwa ndi zakudya, kumayendetsedwa ndi matenda a shuga, ndiye kuti muyenera Met. Ndi matendawa, Reduxine amayenera kumwedwa piritsi lokha.

Limagwirira ntchito Reduxin

Pali mitundu itatu yamanjala ndipo imodzi yokha ya izo ndi yeniyeni mu ndege yakuthupi. Kukumva chilakolako chabodza chofananacho, thupi limasinthira modzikhumudwitsa, ngati nkosatheka kukwaniritsa zosowa zachilengedwe. Makina ochitapo kanthu a Reduxin ndikuti Met, monga mtundu wa inhibitor, akukhudzidwa ndi kapangidwe ka serotonin, komwe kumabweretsa chisangalalo. Izi zimathandiza kuti zigawo zikuluzikulu zizigwira bwino ntchito: sibutramine, yomwe imachepetsa chilimbikitso, kapena metformin, yomwe imachepetsa shuga m'magazi ndikusintha kuchuluka kwa glucose.

Momwe mungatenge Reduxine

Zomwe zimachitika izi kapena mankhwalawa zimayambitsa chiwalo china sichikudziwika. Pali chiopsezo chotenga zotsata zosasangalatsa. Ngati mutenga Reduxine molondola, ndiye kuti mavuto omwe mumakumana nawo akhoza kupewedwa. Musayambe ndi waukulu Mlingo, dziwani nokha 1 kapisozi ndi piritsi 1 patsiku. Pofuna kuti musamve zovuta ndi kugaya kwam'mimba, kuchuluka kwa magawo omwe agulitsidwe sikuyenera kupitirira zidutswa zitatu ndipo muyenera kuzitenga masana, kuonetsetsa zomwe zimachitika. Ndikofunika kukumbukira kuti Reduxin ndi mowa sizigwirizana. Kuphatikiza koteroko kumatha kuyambitsa chidakwa chachikulu ndi zovuta zonse zomwe zikubwera.

Zotsatira zoyipa

Gulu la mankhwala okhala ndi zinthu zazikuluzikulu zotere limatha kukhala ndi zizindikilo zomwe sizachilendo pamavuto omwe amagwiritsidwa ntchito. Chithandizo cha Reduxin ziyenera kutumizidwa ndi dokotala. Amakakamizidwa kufotokozera zomwe zikuyembekezereni chifukwa cha bongo wambiri. Zina mwazotsatira za Reduxin ndi:

lactic acidosis,
kuphwanya masamba okoma,
kudzimbidwa
kukula kwa mavuto a khungu,
kusintha kwa chiwindi,
kusowa tulo
kusokonezeka kwa mtima dongosolo: kuchuluka magazi, tachycardia,
thukuta kwambiri
kupweteka m'mimba
kukokana
matenda amisala: mawonekedwe amanjenje, kupezeka kwa malingaliro ofuna kudzipha,
magazi a m'mimba.

Mtengo wa Reduxin Met

Ndikwabwino kugula mankhwala m'masitolo, koma mutha kuyitanitsa pamndandanda ndikugula m'sitolo yogulitsa pa intaneti. Komabe, pankhani yachiwiri, kusinthanitsa, mwachitsanzo, zinthu zosasanja bwino zimakhala zovuta kwambiri. Chipangizochi ndichotsika mtengo, koma izi sizitanthauza kuti muyenera kudzilingalira nokha ndikupewa kukaonana ndi dokotala. Mtengo wa Reduxin Met umasiyana mtundu wamankhwala ndi ma CD ake:

Mtengo muma ruble

Sibutramine 10 mg makapisozi + 158,5 mg mapadi ndi mapiritsi a 850 mg

Makapu 30 ndi mapiritsi 60

Sibutramine 15 mg makapisozi + 153,5 mg mapadi ndi mapiritsi a 850 mg

Makapu 30 ndi mapiritsi 60

Kanema: Reduxin ndi chiyani

Ekaterina, wa zaka 29 ndakhala ndi chidwi chochepetsa thupi kwa zaka 5 zapitazi. Ndinayamba kulemera nditabereka mwana wamkazi. Kuphatikiza apo, kulakalaka zankhanza kumabwera kuchokera kwinakwake, choncho zakudya sizothandiza kwa ine. Ndinapita kwa asing'anga ndipo adotolo, atachita kafukufuku, adandiuza Reduxin. Ndikutenga mwezi wachiwiri, kulemera kumachoka pang'onopang'ono, ndinayamba kufuna zochepa.

Tatyana, wazaka 37. Zopindulitsa zazikulu za Reduxine kwa ine: mtengo wotsika komanso kupezeka kwa mafakisi. Moyang'aniridwa ndi dokotala, ndakhala ndikumwa mankhwalawa kwa pafupifupi chaka tsopano, ndikupumira pang'ono. Mankhwalawa adandisinthanitsa ndi chakudya: ndikukhala patebulo la zikondwerero, ndimadya monga momwe munthu wamba amakwanira kudya. Ndikukonzekera kupitiliza mpaka nditaona zabwino pagalasi.

Julia, wazaka 33 Kamodzi bwenzi linandiuza njira yochepetsera thupi popanda kuchita khama. Zinapezeka kuti ndi Reduxin.Nditaphunzira malangizo pa intaneti, sindinawonere zovuta zonse zomwe zikundiyembekezera. Ndinkatha kugula mankhwala popanda mankhwala osati movutikira. Patatha sabata limodzi, ndinayamba kumva kupweteka m'mimba, kugunda kwamtima kwambiri ndi thukuta. Chida ichi chidayenera kusiyidwa.

Momwe mungagwiritsire ntchito: Mlingo ndi njira ya chithandizo

Mulingo woyenera wokonzanso wa metformin ndi 1700 mg patsiku. Mlingo wapamwamba tsiku lililonse wa metformin ndi 2550 mg. Kuti muchepetse mavuto kuchokera m'matumbo, gawo la metformin la tsiku ndi tsiku lingagawidwe pawiri. Mwachitsanzo, imwani piritsi 1 m'mawa ndi piritsi 1 yamadzulo.

Ngati mkati mwa masabata 4 kuyambira chiyambi cha chithandizo, kuchepa kwa thupi kwa 2 kg sikunatheke, ndiye kuti mlingo wa sibutramine ukuwonjezeka mpaka 15 mg / tsiku. Kuchiza ndi mankhwalawa sikuyenera kupitilira miyezi yopitilira 3 kwa odwala omwe satsatira bwino chithandizo, i.e. omwe mkati mwa miyezi 3 ya chithandizo sangathe kukwaniritsa kuchepa kwa 5% kuchokera ku chisonyezo choyambirira. Kuchiza sikuyenera kupitilizidwa ngati, pogwiritsa ntchito mankhwala ena pambuyo pakuchepa kwa thupi, wodwalayo amawonjezeranso 3 kg kapena kuposerapo thupi. Kutalika kwa mankhwalawa sikuyenera kupitilira chaka chimodzi, popeza palibe chidziwitso chokwanira ndi chitetezo pokhudzana ndi nthawi yayitali pakutenga sibutramine.

Chithandizo chikuyenera kuchitika molumikizana ndi kadyedwe ndikuchita masewera olimbitsa thupi moyang'aniridwa ndi adokotala odziwa ntchito yochizira kunenepa.

Zotsatira za pharmacological

Mankhwalawa akuphatikiza mankhwala awiri osiyana mu phukusi limodzi: hypoglycemic wothandizira pakamwa pa gulu la ma gluuanides piritsi lalingaliro - metformin, ndi mankhwala ochizira kunenepa mu mawonekedwe a kapisozi kapangidwe kokhala ndi sibutramine ndi cellcose ya microcrystalline.

Metformin ndi mankhwala osokoneza bongo a hypoglycemic ochokera pagulu lalikulu, amachepetsa hyperglycemia, osatsogolera pakupanga hypoglycemia. Mosiyana ndi mankhwala a sulfonylurea, samalimbikitsa kutulutsa insulin ndipo samayambitsa zotsatira za hypoglycemic mwa anthu athanzi. Zimawonjezera chidwi cha zotumphukira zolandilira ku insulin ndikugwiritsa ntchito shuga ndi maselo. Amalepheretsa gluconeogenesis m'chiwindi. Imachedwetsa mayamwidwe am'mimba m'matumbo. Metformin imathandizira kapangidwe ka glycogen pochita glycogen synthase. Kuchulukitsa kuchuluka kwa mayendedwe amtundu uliwonse wa ma membrane glucose. Ilinso ndi phindu pa metabolidi ya lipid: imatsitsa cholesterol yathunthu, lipoproteins yotsika komanso triglycerides.

Ngakhale mutamwa metformin, thupi la wodwalayo limakhalabe lolimba kapena limatsika pang'ono.

Sibutramine ndi mankhwala osokoneza bongo ndipo amakhala ndi vivo chifukwa cha metabolites (ma pulamu oyambira ndi sekondale) omwe amalepheretsa kubwezeretsanso kwa monoamines (serotonin, norepinephrine ndi dopamine). Zimathandizira kukulitsa kumverera kwodzaza komanso kuchepetsa kufunika kwa chakudya, komanso kuwonjezera mafuta opanga. Pogwiritsa ntchito molakwika ma beta2-adrenergic receptors, sibutramine amachita pazinthu zodontha za bulauni. Kutsika kwa kulemera kwa thupi kumayendera limodzi ndi kuwonjezeka kwa ndende yamagazi a lipoproteins yapamwamba kwambiri (HDL) ndi kuchepa kwa kuchuluka kwa triglycerides. cholesterol yathunthu, otsika kachulukidwe lipoproteins (LDL) ndi uric acid. Sibutramine ndi metabolites ake sizikhudza kutulutsidwa kwa ma monoamines, osalepheretsa monoamine oxidase (MAO): alibe mgwirizano ndi kuchuluka kwa ma neurotransmitter receptors, kuphatikizapo serotonin, adrenergic, dopamine, muscarinic, histamine, benzodiazepine ndi glutamate receptors a NMDA.

Ma cellulose a Microcrystalline ndi enterosorbent, ali ndi mphamvu za matsenga ndi mphamvu yopanda tanthauzo. Amamanga ndikuchotsa tizilombo tating'onoting'ono tambiri, zopangidwa ndi ntchito yofunika kwambiri, poizoni wa chilengedwe komanso chilengedwe, ma allergen, xenobiotic, komanso kuchuluka kwazinthu zambiri za metabolic komanso metabolites zomwe zimayambitsa kukula kwa endo native toxicosis.

Kugwiritsa ntchito munthawi yomweyo mankhwala a metformin ndi sibutramine omwe ali ndi cellcrystalline cellulose kumawonjezera mphamvu ya kuphatikiza komwe kumagwiritsidwa ntchito kwa odwala omwe ali ndi matenda onenepa kwambiri komanso mtundu wa 2.

Kufotokozera za mankhwalawa

Reduxin Met ndi mankhwala amphamvu omwe amathandizira kusintha thupi, kuchepetsa shuga, komanso kuthana ndi chidwi. Awa ndi mankhwala omwe sanapangidwe kuti mugwiritse ntchito musanapume kaye ndi dokotala. Popeza anthu ambiri amafuna kuchepa thupi, chizolowezi chomwera mankhwalawa ndichapamwamba. Ndemanga zomwe zapezeka za Reduxin Met zimawonetsa kuti zimachepetsa kumverera kwanjala, komanso zimayambitsa zovuta zingapo, kotero sizili zoyenera kwa aliyense. Awa si mankhwala otsika mtengo. Mtengo wa Reduxin Met ndi pafupifupi ma ruble 2000 phukusi lililonse. Ili ndi malo ena angapo amitundu yamagulu osiyanasiyana, ofanana ndi kapangidwe kake. Koma ndi adokotala okha omwe angadziwe kuti ndi mankhwala ati omwe amayenera kumwa. Ma analogi a Reduxin Met akuphatikizapo Glucofage, Metformin, Metfogamma, Siofor popanga, ndi Bisogamma, Glyurenorm, Glimeperid, Maninil, ndi ena.

Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD

Reduxin Met imaperekedwa kwa ogula ngati mitundu ya mankhwala a piritsi ndi ufa wa kapisozi. Mapiritsi oyera otsekemera amakhala ndi mamiligiramu 850 a metformin hydrochloride (mankhwala othandizira), ma crystallites a microfibril cellulose, croscarmellose sodium, polyvinylpyrrolidone, mchere wa magnesium wa stearic acid ndi madzi oyeretsedwa. Makapisozi amtundu wabuluu kapena wabuluu wokhala ndi zinthu zoyera za ufa mkati mwake muli mamiligalamu 10/15 a sibutramine hydrochloride monohydrate, mamiligalamu 158,5 / 153,5 a microcrystalline cellulose (zosakaniza), calcium stearic acid (gawo lina), utoto, gelatin, zoyera za titanium (thupi) . Tiyenera kukumbukira kuti sibutramine adalembedwa mndandanda wazinthu zomwe zimagwiritsidwa ntchito polingalira za Art. 234 ya Criminal Code of the Russian Federation, yomwe imakhazikitsa chilango chifukwa chogulitsa mosaloledwa zinthu zamphamvu. Mtengo wa Reduxin Met zimatengera kuchuluka kwa mapiritsi / makapisozi ndi zomwe zimagwira mwa iwo. Mapiritsi ndi makapisozi onse amaikidwa zidutswa 10. m'matumba a foil ndi PVC, omwe amakhala ndi makatoni okhala ndi 20/60 mapiritsi ndi 10/30 makapisozi, motsatana. Mutha kugula Reduxin Met popereka mankhwala kuchokera kwa dokotala. Kuti mudziwe za kupezeka kwa Reduxin Met ku Moscow, kuti mufotokozere za mtengo wake komanso kuthekera kwa kubereka, mutha kudutsa patsamba la masamba kapena pafoni.

Malangizo apadera

Ndi kulephera kwa aimpso, theka la moyo limawonjezeka, lomwe lingayambitse kuchulukana m'thupi la metformin kapena zovuta zomwe zimayambitsa. Izi, zimatha kuyambitsa kukula kwachilendo, koma koopsa - kukomoka kwa lactic, komwe kumatha kubweretsa imfa popanda chithandizo chamankhwala choyenera. Kuchepa kwa kukhazikika kotereku kumachulukirachulukira mwa anthu omwe ali ndi matenda osokoneza bongo otseguka, kudzikundikira kwa matupi a ketone, kufunitsitsa kwa mowa, kufa ndi njala kwa nthawi yayitali, matenda oopsa a hypoxia. Ndi kulephera kwa chiwindi ndi chiwonetsero cha hepatomegaly, kupweteka, colic, jaundice pakhungu ndi mucous nembanemba ndi gawo limodzi la sibutramine, kuchuluka kwathunthu kwa zinthu zomwe zimagwira pakukonzekera kwake (M1 ndi M2) m'magazi ndi kotala kuposa omwe alibe mavuto a chiwindi. Izi zitha kuchititsanso lactic acidosis. Kuthekera kotukuka kwa lactacidemia kuyenera kuganiziridwa ngati wodwalayo atakhudzika ndi minyewa, ndikumva kupweteka pamimba pamatumbo osadziwika, kutentha kwapakhosi, kumverera kwadzaza m'mimba, ndi zina zambiri. Zizindikiro za lactic acidosis ndizovuta kupuma, kupweteka pamimba, kutsika kwa kutentha kwa thupi ndi chikomokere kumapeto. Mu ma laboratore amasanthula, lactic acidosis imawonetsedwa ngati kuchepa kwa pH ya 5 mmol / l, kusiyana pakati pa kuyeza kwa cations ndi anions, kuchuluka kwa lactic ndi pyruvic acid. Powonetsa koyamba matenda osokoneza bongo omwe ali ndi asidi, muyenera kusiya kumwa mankhwalawo ndikudziwitsa dokotala nthawi yomweyo. Njira zochizira opaleshoni zimatha kuchitidwa patangotha masiku awiri mutasiya kugwiritsa ntchito Reduxine Met. Kubwerera kugwiritsa ntchito mankhwalawa pambuyo pakuchita opaleshoni ndikololedwa pambuyo pa masiku awiri ndikugwira ntchito bwino kwa impso. Popeza ntchito ya impso ndi kufafaniza kwa metformin ndizogwirizana kwambiri, kuyesa kwa labotale kuyenera kukhazikitsidwa musanachitike komanso nthawi ya mankhwalawa kamodzi pachaka mwa anthu omwe ali ndi impso wathanzi, miyezi isanu ndi umodzi iliyonse kapena miyezi itatu mwa okalamba kapena odwala CC. chilolezo. Kugwiritsira ntchito mosiyanasiyana kwa Reduxin Met ndi mankhwala omwe amachepetsa kuthamanga kwa magazi, okodzetsa kapena opaka mafuta ayenera kuchitidwa moyang'aniridwa ndi achipatala mosamala kwambiri. Chenjezo lofananalo limafunikira mukaliphatikiza ndi insulin kapena mankhwala ena aliwonse a hypoglycemic. Zakudya zokhala ndi zopatsa mphamvu zama calorie komanso kudya mafuta okwanira tsiku ndi tsiku ziyenera kuchitika nthawi yonse ya kumwa mankhwalawa. Kuwunika kwawogwiritsa ntchito glycemic ya odwala matenda a shuga kuyenera kuchitika mwadongosolo. Reduxin Met imalembedwa pomwe ndizosatheka kukwaniritsa thupi popanda kugwiritsa ntchito ma pharmacological othandizira, ndipo njira zina m'miyezi itatu zathandizira kuchepetsa kulemera kwa thupi ndi zosakwana 5 kg. Chithandizo cha kunenepa kuyenera kuchitika mokwanira ndi dokotala yemwe akudziwa bwino izi. Kuphatikiza pa kumwa mankhwala ophatikizidwa ndimkati, ndikofunikira kusintha zizolowezi zodya, kukhala ndi moyo wogwira ntchito, womwe ungakuthandizeni kusunga zotsatira kumapeto kwa mankhwala. Kupanda kutero, mudzafunikira chithandizo chamankhwala ndi dokotala. Mukamagwiritsa ntchito Reduxin Met, ndikofunikira kuyang'anira kuchuluka kwa kukakamizidwa ndi kugunda kwa mtima: kamodzi sabata ziwiri m'miyezi itatu yoyambirira, kenako kamodzi pamwezi. Ngati mukuyendera kwa dokotala kawiri konse, kugunda kwa mtima kupumula kunali kwakukulu kapena kofanana ndi kugunda kwa mphindi 10 kapena kuthamanga kwa magazi ≥10 mm Hg, mankhwalawa ayenera kusiyidwa. Ngati odwala omwe ali ndi vuto la kuthamanga kwa magazi omwe akumwa mankhwala a antihypertensive, kupanikizika kumakhalabe kwa mlingo wa> 145/90 mmHg, kuyenera kuyang'aniridwa pafupipafupi kuposa kukhazikitsidwa kwa odwala ena. Mwanjira imeneyi, zizindikiro zobwereza kawiri kuposa mlingo uwu ndizomwe ziyimitsidwa kwa chithandizo. Odwala omwe ali ndi CHF, Reduxin Met imawonjezera chiopsezo cha kugona ndi okosijeni komanso kulephera kwa impso, chifukwa chake, kuwunikira kwamtima ndi impso ndikofunikira kwa iwo. Ngati muli ndi matenda obanika kutulo, muyenera kusamala kwambiri pakuwunika magazi. Ngakhale sizinatsimikizidwe kuti kutenga sibutramine kumatha kuyambitsa kuthina mkati mwa chotupa cha m'mapapo komanso kuwonjezeka kwathunthu kwam'mapapo, gulu ili lidakali ndi chiopsezo, chifukwa chake, mukapita kukaonana ndi dokotala, ndikofunikira kumamuwuza za kupuma, kupweteka pachifuwa komanso kutupa kwa miyendo . Ngati imodzi mwa mankhwalawa yakusowa, yotsatira imachitika molingana ndi dongosolo lokhazikitsidwa. Imwani mlingo womwe mwasowa nthawi yomweyo ndi wotsatira. Njira yochizira singathe kupitirira chaka chimodzi. Kugwiritsanso ntchito kwa sibutramine ndi mankhwala ena omwe amachepetsa kubwezeretsanso kwa serotonin kumawonjezera mwayi wokhetsa magazi. Wodwala akakhala kuti amakonda kukula kapena kumwa mankhwala omwe amakhudza magazi, Reduxine Met iyenera kumwedwa mosamala. Ngati pali mbiri yakudalira kwa pharmacological, sibutramine siinakhazikitsidwe. Kuvomerezedwa kwa mankhwalawa ndi odwala omwe ali ndi prediabetes ndizovomerezeka ngati pali zofunikira zotheka kupanga matenda osagwirizana ndi insulin: zaka 30 kg / m. sq., matenda a shuga chifukwa cha kubereka mu anamnesis, kuchepa kwa insulini m'thupi la abale oyamba kinship, kuchuluka kwa triacylglycerides, kuchuluka kosakwanira kwa cholesterol "chabwino", kuthamanga kwa magazi kunalembedwa. Reduxin Met imatha kusokoneza kayendetsedwe ka galimoto kapena njira zina, imachita zinthu zoopsa, imasokoneza chidwi komanso kuthamanga posankha zochita.

Bongo

Malinga ndi malangizo ogwiritsira ntchito Reduxin Met, mankhwala ochulukirapo a metformin ndi sibutramine amadziwulula mosiyanasiyana. Metformin, pamankhwala oposa 40 nthawi tsiku lililonse, amatha kuyambitsa kukomoka kwa lactic. Zizindikiro zoyambirira za mankhwala osokoneza bongo zikawoneka, mankhwalawa amaletseka, wodwalayo amagonekedwa kuchipatala mwachangu, kuphatikizidwa kwa lactic acid kumatsimikiziridwa kuchipatala, komwe, pamodzi ndi metformin, amathandizidwa ndi hemodialysis. Chithandizo cha zizindikiro ndi mankhwala. Mankhwala osokoneza bongo a sibutramine amagwirizanitsidwa ndi kuchuluka kwa kukakamiza, kugunda kwa mtima mopitirira 90 kumenyedwa. mu min., mawonekedwe a mutu, kumva kuzungulira kwa zinthu zozungulira kapena thupi lanu. Izi ziyenera kudziwitsidwa kwa dokotala. Palibe mankhwala, mapangidwe a kuchuluka kwa mkodzo mu kuchuluka kwa mkodzo wa thupi kapena njira ya hemodialysis sikunatsimikizike. Kuperewera kwa sibutramine kumachepetsa kutsekeka kwa m'mimba ndi kudya kwa sorbent. Pofuna kuthana ndi mawonekedwe a bongo wambiri, muyenera kupanga njira zopumira mwaulere, kuwongolera ntchito ya mtima ndi mitsempha yamagazi, ndikuwathandiza. Beta-blockers amalembedwa kwa odwala omwe ali ndi kuthamanga kwa magazi komanso kuwonjezeka kwa kuthamanga kwa mtima (HR) kwa oposa 90 pamphindi. Ngati mumagwiritsa ntchito mlingo wambiri wa mankhwalawa ndikuwonetsa zizindikiro zogwirizana, Reduxine Met imathetsedwa.

Reduxin kapena Reduxin Met: kusiyana kwake ndi chiyani?

Zonsezi zakonzedwa kuti zithandizire kunenepa kosiyanasiyana, pamene njira zina zochitira ndi mapaundi owonjezera sizimapereka zotsatira zomwe mukufuna. Ichi ndi chimodzi mwazipatso zamphamvu kwambiri zomwe zochita zake zimayatsidwa kuti atenthe mafuta amthupi. Kutulutsidwa kwa mitundu yonse iwiri ya Reduxine ndi mankhwala mosamalitsa.

Ngakhale kuti mankhwalawa ali ndi mayina ofanana, kapangidwe kazomwe zimagwira mosiyanasiyana. Reduxin Met imakhala ndi zigawo ziwiri za sibutramine ndi metformin, pomwe Reduxin wamba amangokhala ndi sibutramine. Mankhwala onsewa ndi anorexigenic, amachepetsa kufunikira kwakuthupi kwamunthu chakudya, amathandizira kuthamanga kwamafuta ndikuchotsa poizoni m'thupi.

Metformin, yomwe ndi gawo la Reduxin Met, imathandizira mphamvu ya sibutramine ndikukulitsa mphamvu ya pharmacological yamankhwala. Mankhwalawa amathandizira kuchotsa cholesterol yambiri m'thupi, imachepetsa shuga.

Odwala onenepa kwambiri ambiri akudandaula kuti: Reduxin kapena Reduxin Met, ndiwothandiza kwambiri? Mankhwala omaliza ali ndi zabwino zambiri, ngakhale zimawononga zochulukirapo.Njira yowotcha mafuta kumbali yakudya kwake imathamanga kwambiri. Sibutramine yowonjezeredwa ndi metformin imaloledwa kugwiritsidwa ntchito mu mtundu wa shuga 2.

Mapangidwe a "Reduxin Met", mawonekedwe omasulidwa

Mankhwalawa akuphatikiza mankhwala awiri osiyana mu bokosi limodzi. Chidacho chili ndi mapiritsi a 850 mg ndi 10 mg + 158.5 mg makapisozi. Mu bokosi la makatoni, mapiritsi 20 kapena 60 a metformin, makapu 10 kapena 30 a sibutramine amadzaza.

Mapiritsiwo amakhala ndi chowulungika, chowoneka bwino mbali zonse ziwiri, yogawidwa ndi mphako. Reduxin Met imapezeka m'matumba a foil 10. Atayikidwa m'makatoni okhala ndi matuza awiri kapena 6. Chofunikira ndi metformin hydrochloride. Zowonjezera:

Cellulose (microcrystalline),
Povidone
Magnesium wakuba,
Madzi osalala
Croscarmellose sodium.

Makapisozi amadzaza matuza a ma PC 10. ndi 1 kapena 3 maselo a contour mu bokosi limodzi. Mkati mwakonzedwa womata muli ufa kapena wachikasu, chipolopolo chimakhala ndi mtundu wa buluu. Chogulitsachi chimaphatikizapo ziwiri zosagwira: 10 mg ya sibutramine hydrochloride monohydrate ndi 158,5 mg wa microcrystalline cellulose. Pazinthu zothandizirana pakuphatikizika kwa magnesium yokha yochepa.

Mpaka pano, mankhwalawa "Reduxin Met", 15 mg. Kuphatikizika kwake komwe kumaphatikizapo 5 mg kwambiri sibutramine ndi cellulose yocheperako.

Sibutramine

Mankhwala amalimbikitsa kuyambika msanga kwa kudzimva kwache komanso kumachepetsa kufunikira kwa chakudya kowonjezera. Chifukwa chogwiritsa ntchito sibutramine, kuwonda kwambiri kumachitika. Pamodzi ndi izi, ma laboratori ammagazi amawongolera: cholesterol imachepa, uric acid yowonjezera imachotsedwa.

Microcrystalline mapadi

Mankhwalawa amakhala ndi mitundu yambiri yazakudya ndipo amatha kusintha zinthu mthupi. Choyamba, ndi logosorbent yogwira mtima yomwe imathandizira kuchotsa zinthu zowola, zinthu zoopsa, ziphe za thupi kuchokera mthupi, komanso ma metabolites osiyanasiyana omwe amachititsa kuti pakhale endo native toxicosis. Kuphatikiza apo, mapadi amathandizira kulimbitsa chitetezo cha mthupi, kusintha cholesterol, kumapangitsa kugaya chakudya ndi kagayidwe kachakudya.

Chifukwa cha kuphatikiza kwa mankhwalawa, Reduxin Met lero ndi njira imodzi yothandiza kwambiri polimbana ndi kilogalamu yowonjezera. Amaloledwa kugwiritsidwa ntchito ngakhale ndi odwala; kupezeka kwa matenda a shuga a 2 kwakhazikitsidwa.

Sibutramine ndi mankhwala a kunenepa kwambiri (chakudya) kunenepa kwambiri kwa omwe thupi lawo limakhala lalikulu kuposa 30 kg / m². Pamaso pa matenda ena achilendo, mwachitsanzo, matenda a shuga kapena lipid metabolic, Reduxine Met imalimbikitsidwa kuti igwiritsidwe ntchito ndi BMI ya 27 kg / m² kapena kuposerapo.

"Reduxin Met" 10, 15 mg malangizo ogwiritsira ntchito

Makapiritsi ndi mapiritsi amagwiritsidwa ntchito pakamwa. Amakhala oledzera nthawi yomweyo m'mawa ndi zakudya, ndikumwa madzi ambiri. Mlingo wocheperako ndi piritsi limodzi la metformin (0.85 g) ndi 1 kapisozi ya sibutramine (10 mg).

Ngati shuga wamagazi aposa zomwe zimachitika, ndiye kuti pamafunika kuwunika kusintha kwake pamasamba oyamba ovomerezeka. Ngati malingaliro abwinobwino masiku 14 sakwaniritsidwa, ndiye kuti mlingo wa metformin umakulitsidwa kumapiritsi awiri. Ndikothekanso kuchepetsa kuopsa kwa zovuta zomwe zimachitika m'matumbo ngati gawo la tsiku lililonse limagawika m'magawo awiri ofanana.

Kuchepetsa thupi kumachitika pambuyo masiku 30. Ngati munthawi imeneyi kuchepa kwamankhwala sikunakhazikike, kapena sikunapitirire 2 kg, ndiye kuti Reduxin Met, 15 mg ndi wokhazikika. Ngati kumwa kochita bwino mkati mwa miyezi itatu kulemera kwa wodwalayo sikucheperachepera 5 kapena kuposa, ndiye kuti mankhwalawo amayimitsidwa chifukwa cha kusachita bwino kwake. Kuchiza kumathetsedwanso ngati, malinga ndi momwe ntchito mankhwalawo ikukula, kuchuluka kwamakilogalamu atatu kapena kuposerapo kumachitika.

Malangizo a rexin, komanso metformin, ayenera kufotokozedwa ndi dokotala. Njira yochiritsira nthawi zambiri simapitilira 1 chaka. Kumwa mankhwala kuyenera kuphatikizidwa ndi zakudya zapadera komanso kuchita masewera olimbitsa thupi tsiku lililonse.

Mawonekedwe

Chifukwa chotenga metformin, chiopsezo cha mkhalidwe wowopsa monga lactic acidosis imachulukitsidwa kwambiri. Ichi ndi vuto lalikulu lomwe limachitika chifukwa chopanga gawo lomwe limagwira, lomwe limatitsogolera kuimfa. Kwenikweni, lactic acidosis anapezeka mwa odwala matenda amtundu wa 2, osakwanira aimpso ntchito.

Ngati opaleshoni yakonzekera, kulandiridwa kwa Reduxine Met kuyenera kuthetsedweratu masiku awiri musanachitike mankhwalawa ndipo kuyambanso kuyambikanso masiku awiri atatha ngati dongosolo la impso likugwira ntchito bwino. Kusamalidwa makamaka kuyenera kuthandizidwa popereka matenda a sibutramine kwa okalamba omwe ali ndi vuto laimpso.

M'zaka makumi angapo ndikuyambirira kwa kutenga Reduxine Met, odwala ayenera kuwunika kuthamanga ndi kuthamanga kwa mtima. Ngati chiwonetsero chawonjezereka kawiri pakuwonetsa chizindikiro chimodzi kapena chachiwiri ndi pafupipafupi kwa milungu iwiri, chithandizo chikuyenera kutha.