Zizindikiro za shuga mwa amuna
Matenda a shuga ndi matenda omwe amawoneka ndi shuga wambiri m'madzi a m'magazi chifukwa chosowa insulini kapena kusakhalapo kwathunthu. Mawu akuti "insulin" amatanthauza mahomoni omwe kapamba amayambitsa.
Timadzi timene timayendetsa kagayidwe. Kwambiri, zimakhudza kuchuluka kwa shuga ndipo pokhapokha pamapangidwe a mapuloteni ndi mafuta. Wodwala akapezeka kuti ali ndi vuto la insulin, titha kufotokoza za zovuta za metabolic, zomwe zimapangitsa kuchuluka kwa shuga m'magazi.
Vutoli limatchulidwanso kuti hyperglycemia. Thupi limayesetsa kuthana ndi shuga owonjezera, kotero ambiri amachotsedwa limodzi ndi mkodzo. Kuphatikiza apo, kapangidwe ka magazi kamasinthanso. Matupi a Ketone amawoneka m'magazi, zomwe ndi zinthu za acidic zomwe zimachokera ku mafuta osokoneza.
Pali mitundu iwiri yosiyanasiyana ya matenda ashuga. Matenda a shuga amtundu woyamba amakula chifukwa chopanga ma antibodies enaake m'thupi omwe amawononga ma cell omwe amapanga insulin ndi kapamba.
Matenda a shuga a Type 1 ndi matenda osachiritsika. Kugwira bwino ntchito kwamthupi kumathandizidwa ndi kuyambitsa insulini pogwiritsa ntchito syringe kapena zida zina zapadera. Mawonekedwe a piritsi la mahomoni kulibe, chifukwa amawonongeka ndikulowa m'mimba.
Pankhaniyi, jakisoni amachitika mosamalitsa pakudya. Kuphatikiza apo, wodwalayo ayenera kutsatira zakudya zosasunthika, zomwe zimaletsa kudya zakudya zam'mimba zomwe zimapezeka mofulumira, kuphatikizapo maswiti osiyanasiyana, shuga, misuzi yokhala ndi shuga ndi zina zambiri.
Pankhaniyi, mtundu wachiwiri wa matenda a shuga umayamba pang'onopang'ono, chifukwa kapamba amapanga insulin, koma sikokwanira kukwaniritsa zosowa zathupi.
Choyambitsa chitukuko cha matendawa nthawi zambiri chimakhala kuperewera kwa zakudya m'thupi, kukhalabe ndi moyo wokhala phee komanso kunenepa kwambiri. Ngati munthu wonenepa kwambiri, maselo ake amakhala ndi michere yambiri. Ndiye chifukwa chake, pakapita nthawi, amayamba kusiya kumva za insulin.
Zolinga za maonekedwe
Matenda a shuga amuna azaka 30 mpaka 35 amatha kuchitika pazifukwa zingapo:
- Kudziwikiratu kudzivulaza ndi chinthu chofunikira kwambiri. Chifukwa chake, ngati mayi kapena abambo a mwamunayo akudwala matenda ashuga, mwayi woti tso lake lingamufikire mwana limakhala pafupifupi 30 peresenti.
- Kunenepa kwambiri mu shuga ndi chizindikiro chofunikira kwambiri cha matendawa. Ngati munthu akudziwa kuthekera kwake kwa matendawa, amafunika kuwongolera osati zomwe zili m'magazi okha, komanso kulemera kwake komwe.
- Matenda a pancreatic omwe amawononga maselo a beta. Zitha kuphatikizaponso zinthu zoopsa.
- Kugwedezeka pafupipafupi kwamaganizidwe ndi nkhawa zam'mananso ndizinthu zomwe zikukulitsa.
- Matenda a ma virus, omwe akuphatikiza nthomba, rubella, hepatitis, fuluwenza ndi zina zambiri. Matenda amatha kubweretsa matenda ashuga.
- Zaka zakubadwa zaka 36 - 40 mwa amuna zimadziwikanso ngati chifukwa choopa matenda ashuga. Komabe, ndikofunikira kudziwa kuti chibadwidwe chamtsogolo chokhala ndi ukalamba sichimatha kuchita mbali yofunika kwambiri.
Zizindikiro zoyambira
Pali zodziwika za matenda ashuga mwa amuna ochepera zaka 30 ndipo atatha zaka 31. Pakati pawo, pali zizindikiro zazikulu zingapo zomwe zimakupatsani mwayi wodziwa matenda kuti mupewe kukula.
Mafuta ochulukirapo amakhudza thupi lonse lathunthu, komanso ntchito zomwe kapamba imayang'anira, ndipo amasiya kuthana nalo kwakanthawi. Chifukwa chake, kuchuluka kwa shuga kwa plasma kumawonjezeka, zomwe zimatsogolera pakupanga shuga.
Zizindikiro zoyambirira za matenda ashuga mwa amuna omwe ali ndi zaka 32 mpaka 33 zikuphatikiza ndi izi:
- Kuchulukitsa thukuta.
- Kuyabwa kosakhudzidwa m'malo a groin omwe samachoka.
- Maonekedwe a mibadwo ya pakhungu kapena pankhope.
- Kuchepetsa thupi kapena kuwonda.
- Kulakalaka kwambiri, ngakhale munthuyo atangodya. Komanso ludzu lakumwalira pamene munthu sangathe kuledzera.
- Zosokoneza tulo. Wodwalayo nthawi zonse amafuna kugona, koma kugona kumasokoneza komanso kupuma.
- Kutopa posakhalitsa katundu.
- Kuvulala kwamabala ambiri.
- Maonekedwe a zilonda zam'miyendo pa mwendo.
PepaniM'mwezi wa June, machitidwewa akuwonetsanso kuti amuna ambiri azaka zopitilira 34 samvera chidwi ndi mtundu uwu wa chizindikiro. Kufooka, kutopa kwambiri, kulakalaka kudya ndi zina zambiri nthawi zambiri sizimayenderana ndi kuyambika kwa matenda ashuga, chifukwa chake amanyalanyazidwa.
Ndikofunika kudziwa kuti gawo loyambirira la matendawa ndilosavuta kuchiza. Ndikokwanira kuti wodwalayo ayambe kuchita zinthu zolimbitsa thupi munthawi yake, kudya moyenera, komanso kuyendera endocrinologist pafupipafupi. Pakulimbitsa kwenikweni, wodwalayo amayeneranso kusiya zizolowezi zoipa ndikumwa njira yapadera yolimbikitsidwa.
Amuna atakwanitsa zaka 39 kapena zaka zilizonse akudwala matenda ashuga, Zizindikiro zingapo zomwe ndizosiyana ndi kugonana kwa amuna zimatha kusiyanitsidwa. Kukula kwa matendawa kumabweretsa kuwonjezeka kwa zizindikiro zake zamankhwala, zomwe zimasonyezedwanso mu thanzi la abambo.
Matenda a shuga amakhalanso ndi mavuto owononga pakubala komanso ntchito yogonana. Zizindikiro zoyambirira zikanyalanyazidwa kwa nthawi yayitali, zimasinthidwa ndi zizindikiritso zazikuluzikulu za matendawo. Popita nthawi, bambo amayamba kuwona kusowa kwa chilakolako chogonana, kuchepa kwa potency. Palibe amene angalephere kuwona chizolowezi chomangika musanachitike.
Zilonda zam'mimba zimavutikanso, zimakutidwa ndi ming'alu yosawoneka bwino, khungu limakhala louma kwambiri, lopendekeka ndikuonda. Kuchiritsa microran kumatenga nthawi yayitali, zomwe zimathandiza kuti matenda a fungus ndi viral athere.
Kuphatikiza apo, mwachitsanzo, bambo wazaka 37 ayenera kutembenuka pafupipafupi, komwe sikuima nthawi yayitali. Mutha kuthana ndi izi pokhapokha mwa kusankha zovala zoyenera zaukhondo, kutanthauza shampu, sopo, gel osambira ndi zina zotero. Zabwino kwambiri pakhungu lowonda kwambiri.
Chithandizo cha matenda ashuga ngati zaka 38 zakubadwa komanso zaka zina zilizonse zikuyenda bwino ziyenera kukhala pa nthawi yake. Ngati zizindikiro zoyambirira za matendawa zikunyalanyazidwa, bambo amayamba kuchepa kwambiri popanga testosterone, yomwe imalowetsa kuphwanya kwamitsempha yamagazi m'magazi amchiberekero.
Kuperewera kwa maliseche kumathandizira kukulitsa kusabala. Kuphatikiza apo, ziyenera kudziwika kuti ntchito yobereka imakhudzidwa kwambiri. Kuwonongeka kwamakhalidwe oyenera a umuna, komanso kuchuluka kwake, amadziwika.
Kuphatikiza apo, odwala matenda ashuga amabweretsa chiopsezo cha kuwonongeka kwa DNA, pomwe chidziwitso cha makolo chimafalikira.
Chifukwa chiyani akuyenera kuthandizidwa?
Ngati mumvera kwambiri za chithandizo cha matenda ashuga, kutsatira malangizo onse a dokotala, ndikofunikira kudziwa kuti matendawa alibe choopsa pamoyo. Komabe, kusowa kwa chithandizo choyenera kumabweretsa zovuta zambiri.
Mavuto ambiri ndi awa:
Matenda ogona (apnea) nthawi zambiri amawonedwa mwa anthu odwala matenda ashuga azaka zopitilira 30. Zimayendera limodzi ndi kusowa tulo, kudzutsidwa pafupipafupi, zovuta za usiku komanso mavuto ena ogona.
Kutupa kwachilendo kapena kwachilengedwe kumawonekera kwa odwala omwe amawonjezera omwe ali ndi vuto la mtima. Chizindikiro ichi chikuwonetsanso kukanika kwa impso.
Matenda owopsa kwambiri kuchipatala amatengedwa kuti ndi matenda a shuga. Zizindikiro zisanafike izi zimachitika mosayembekezereka. Izi zimaphatikizapo chizungulire, kukopa, kusokonezeka kwa malingaliro, komanso kukomoka.
Popewa zovuta, ndikokwanira kuti wodwala amwe mankhwala omwe amachepetsa shuga m'magazi munthawi yake, kutsatira zakudya, ndikukhala ndi moyo wapa mafoni. Chithandizo choyenera chidzaiwala za matenda mpaka kalekale. Kanemayo munkhaniyi akukamba za zizindikiro zazikulu za matenda ashuga.
Mitundu ya Matenda A shuga
International Health Organisation igawa matendawa m'magulu awiri:
- Matenda a Type 1 amapangitsa munthu kudalira insulin. Mwanjira yamatenda amtundu woyamba, maselo ambiri a insulin omwe amatulutsidwa ndi kapamba amawonongeka. Zomwe zimayambitsa matenda zimatha kukhala zosiyanasiyana (ma virus, vuto la autoimmune, kuperewera kwa zakudya, genetics). Nthawi zambiri, mtundu uwu umawonekera mwa anthu osakwana zaka 30. Matenda opatsirana amayambitsa kukokomeza. Popanda insulini, thupi la munthu limaleka kugwira ntchito moyenera ndikuyamwa glucose moyenerera, motero odwala ayenera kulandira zinthuzo kuchokera ku jakisoni.
- Mtundu 2 - osadalira insulin. Pankhaniyi, kugwira ntchito kwa kapamba sikulephera. Zizindikiro za matenda ashuga mwa abambo akuluakulu ndizofanana ndi akazi. Maselo a thupi amakhala insulin (yosagwira). Pazifukwa izi, magazi sangalowe m'mitsempha yamagazi. Zomwe zimayambitsa matendawa ndi izi:
- chibadwire
- zolakwa kumwa mankhwala,
- kuchuluka kwa thupi.
Zolemba zamatenda a matendawa kutengera zaka
Zizindikiro za shuga mwa amuna zimatha kusokonezeka mosavuta ndi nkhawa zamanjenje. Komabe, kuyang'ana koyamba kwa dotolo mukamamufufuza kwathunthu, mayeso odutsa adzakhala othandiza. Mutha kudwala matenda a shuga mudakali aang'ono, mutatha zaka 30, kapena ngakhale 50. Mukachedwa kulandira chithandizo, abambo atatha zaka 40 amayamba kudwala kwambiri. Kulephera kwa Hormonal kumakhudzanso potency, kumayambitsa matenda a prostatitis, kukomoka kwa kusokonekera, kugona.
Pakatha zaka 50, amuna nthawi zambiri amatenga matenda amtundu wachiwiri. Izi zitha kukhala limodzi ndi kupweteka kwamkamwa m'mimba, kupweteka mutu, tsitsi. Monga lamulo, zonsezi zimachitika chifukwa cha ukalamba, osakonda kutembenukira ku mankhwala. Momwe mungadziwire matenda a shuga? Onetsetsani kuti mukumana ndi dokotala woyenera, onani kuchuluka kwa shuga.
Zizindikiro zoyambirira za matenda ashuga mwa akulu zimasinthidwa ndi zizindikiro zazikulu zomwe sizitha kunyalanyazidwa:
- kukodza pafupipafupi,
- ludzu losalekeza
- mabala samachiza, zilonda zam'mimba, zotupa, matenda amatha,
- kutayika kwa tsitsi kumakwera
- mano awonongedwa
- kuchepa kwa chidwi cha malekezero (chala chachikulu chimakweza chovuta).
Njira Zodziwitsira
Zizindikiro za shuga wambiri zimawonetsa kuti munthu akhoza kudwala matenda ashuga. Kuti mudziwe bwino, muyenera kugwiritsa ntchito manambala otsatirawa:
- magazi ndi mkodzo amayendera glucose,
- ndikofunikira kudziwa zomwe zili hemoglobin glycosylated,
- kuyeserera kwa shuga m'thupi
- kupezeka kwa C-peptide, insulini m'madzi a m'magazi.
Kulowa misinkhu yosiyanasiyana.
Gout imakhudza makamaka akuluakulu. Malinga ndi ziwerengero, kuchokera ku gout kumakhudza anthu pafupifupi 100% a planeti ambiri, komanso m'maiko otukuka (West Europe dera, USA) chiwerengero cha anthu omwe akudwala gout chiri pafupi 2%. Kuphatikiza apo, akatswiri akuti chithunzithunzi chenicheni chazosiyana ndizosiyana ndi kafukufukuyu, chifukwa kafukufuku wokwanira amayamba chifukwa cha zovuta zomwe amapeza odwala. Ofufuza zamankhwala nawonso akuti gout, yomwe imawonedwa makamaka kukhala matenda amphongo mpaka m'zaka za zana la 20, mosakhalitsa, ikukhudza amuna ndi akazi onse, ngakhale kuchuluka kwa odwala amuna ndi akazi kumakhalabe kosagwirizana: pa milandu 20 yakuzindikira, matenda amodzi amapezeka mwa amuna azimayi. Chomwe chikuwonjezera kuchuluka kwa matenda opatsirana azimayi akuti ndiwosintha moyo wa anthu, chakudya chochuluka chomwe chimadzaza ndi purines, komanso kuchuluka kwa anthu oledzera. Chizolowezi cha "kupangitsanso" matenda opatsirana m'matumbo chinawululidwanso: ngati matendawa adayamba kuwoneka ndi matenda opha ziwalo kwa amuna azaka zapakati pa 35 mpaka 48, ndiye kuti zaka makumi atatu ndizochepa.
Khalani amuna
Chiwopsezo cha matenda amtundu wa azimayi poyerekeza ndi chachikazi ndi chimodzi mwazinthu ziwiri: chibadwa cha matenda ena, zomwe zimapangitsa kuti matupi athu azikhala ndi X, zomwe zikutanthauza kusapezeka kwa amuna omwe ali ndi chromosome imodzi yamtunduwu, komanso kukula kwa matenda amtundu wa m'mimba chifukwa cha zakudya zopanda thanzi komanso zakumwa mowa, womwe umakonda kwambiri amuna. Kuzindikira mochedwa kumawerengedwa ngati gawo lamatenda amphongo chifukwa cha chizolowezi cha anthuwa kufunafuna chithandizo chamankhwala pamlingo wa nthenda yomwe yayamba ndi zovuta za gouty kapena paziwonetsero zakunja kwa gout mwanjira yolumikizira mafupa.
Zinthu za gout mwa akazi
Mwa akazi, njirayi, yomwe imayendetsedwa ndi kuwonjezeka kwa uric acid ndi kuchuluka kwa mkodzo, makhiristo amchere, mu minofu yofewa, imadziwika ndi kusintha kwa msambo. Munthawi imeneyi, chiopsezo cha matenda a m'mimba chimachitika kwambiri, makamaka ngati pali cholowa chamtsogolo, nthawi zambiri, gout wa azimayi amadziwika ali ndi zaka 50-55. Komabe, cholowa chamtundu wa gout kwa akazi chimangowonetsa mwayi wokhala ndi matendawa, mosiyana ndi wamphongo. Jini yomwe imayambitsa ma enzyme ofunikira kupangira mankhwala a purine amapezeka pa X chromosome, ndipo azimayi amakhala ndi ma chromosome awiri. Chifukwa chake, jini ikawonongeka pa chromosome imodzi, kusagwira ntchito kwake kumalipidwa ndi ntchito yayikulu ya geni losungidwa pamwenso. Ngati pali majini awiri owonongeka mu genome, mwayi wokhala ndi gout mwa akazi ndiwofanana ndi amuna (pafupifupi zana limodzi), ndipo zaka zoyambira matendawa zimacheperanso.
Gout: Zizindikiro ndi chithandizo kwa ana azaka 10
Kukula kwa uric acid mthupi, kapena hyperuricemia muubwana, ndiko kusokonezeka kwachiwiri komwe kumayambitsa matenda kapena matenda oyambitsidwa ndipo sachititsidwa chifukwa cha kubadwa kwa chibadwa. Zomwe zimayambitsa gout mu ana a zaka 10 zimaphatikizira kufa kwa cell, komwe kumayambitsa kupangika kwa purines ndipo kumadziwika chifukwa cha kuchepa kwa madzi m'thupi, kufa ndi njala, kulephera kwa impso ndi zina zomwe zimayambitsa matenda a impso, kupezeka kwa zotupa zoyipa, ndi zina zotere. pali kusowa kwathunthu kapena pang'ono kwa hypoxanthine guanine phosphoribosyl transferase, komanso kuchuluka kwa ntchito ya phosphoribosyl pyrophosphate synthetase.
Zoyambitsa Gout
Kuwonjezeka kokhazikika kwa kuchuluka kwa uric acid m'magazi, zomwe zimapangitsa kuti pakhale mapangidwe amchere amchere ndi kuyika kwake mu minofu yofewa ya thupi, ndiye chifukwa chokhacho chomwe chikukulitsa gout.Gawo loyambirira la hyperuricemia, kudzikundikira kwa uric acid, sikumabweretsa mapangidwe ndi mawonekedwe a makhiristo, komabe, limayimira kusokonezeka kwa metabolic, kuwonetsa koyamba kwa matendawa. Zinthu zingapo zimathandizira kukulitsa kuchuluka kwa uric acid. Zomwe zimapangitsa kuti chibadwa chikhale cholowa, kuchuluka kwa purine kumalowerera m'thupi ndi chakudya ndi madzi, kuwonjezereka kwa purine catabolism, komanso kukhudzana ndi zaka kapena kusayenda pang'onopang'ono kwa uric acid excretion kuchokera mthupi mukamayamwa.
Chibale pakati pa chitukuko cha gout ndi kuchuluka kwa uric acid
Mukukonza zitsulo za purine zomwe zimalowa m'thupi ndi chakudya kapena zimapangidwa chifukwa chakutha kwa maselo awo, uric acid amapangidwa. Pulogalamuyi imasefedwa ndi a impso glomeruli ndipo nthawi zambiri imachotsedwa m'thupi limodzi ndi mkodzo. Ngati pa gawo lililonse pali zovuta (kuchuluka kwa uric acid, kusowa kwa chidwi, kuchoka), zomwe zimapangitsa kuti pakhale hyperuricemia zimapangidwa. Ndikofunika kukumbukira kuti kuzindikira kwa "hyperuricemia" sikofanana ndi kukhalapo kwa gout, chifukwa kuchuluka kwa uric acid kumatha kukhala chizindikiro cha matenda ena. Koma hyperuricemia imatha kupangitsa kuti gouty ikule. Ndi gout, uric acid, yomwe imalowa m'magazi amtundu wa calcium, calcium, potaziyamu ndi zinthu zina, imasinthidwa kukhala mankhwala a crystalline kapena urates. Urate imadziunjika mu tiziwalo tating'onoting'ono tating'ono tomwe timatanthauzika: ziwalo za kwamikodzo (impuritsa miyala mu impso, chikhodzodzo) komanso minyewa yofewa ya mafupa, minofu ya periarticular - urate imagwera ndikukhazikika pamenepo chifukwa chazovuta za mayendedwe amwazi m'magazi athupi.
Mlingo wa kaphatikizidwe wa purine nucleotides monga chinthu chothandizira mukukula kwa gout
Kuwonongeka kwa mabeseni a purine, omwe amatsogolera pakupanga uric acid, nthawi zambiri amakhala ndi kukhazikika, komwe kumatsimikiziridwa ndi kuchuluka kwa ma enzyme. Ndi kuchuluka kwa purines m'thupi chifukwa cha kuchuluka kwawo kwa chakudya, kusweka kwakukulu kwa maselo awo kapena njira zina zothandizira ndi kulowerera, kuchuluka kwa kaphatikizidwe kumawonjezeka, ndikupanga kuchuluka kwa uric acid m'magazi, zomwe zimapangitsa kuti pakhale gout. Njirayi imatha kukhala yakanthawi, yosinthika mosavuta, kapena kukhala yayitali chifukwa cha matenda osachiritsika, kuphwanya kawirikawiri zakudya zoyenera. Kuphatikiza kwamphamvu kwa maziko a nyukiliya kumayambitsanso njira zambiri za cytostatic mankhwala, wailesi ndi chemotherapy, hemolysis, mitundu ina ya njira zochitira opaleshoni.
Mlingo wa kuphipha kwa uric acid m'thupi
Gout monga matenda achiwiri amakula motsutsana ndi maziko a vuto laimpso. Pambuyo pokonza ndi kusefa ndi a impso glomeruli, uric acid nthawi zambiri imachoka m'thupi ndi mkodzo. M'matenda a impso, njira yochotsa zimbudzi zamkati za purine zimatha kusokonekera, zomwe zimapangitsa kuti azikhala ndi uric acid m'magazi. Zinthu zikuluzikulu zomwe zimalepheretsa kuwonongeka kwa uric acid ndi kufalikira kwa kufalikira kwa ma ducts chifukwa cha kutukukira kapena kuchuluka kwa minofu yolumikizika.
Purine Wowonjezera
Ngakhale kumwa kwambiri zakudya zamafuta mu purines sikuti kumabweretsa kukula kwa matendawa, zimapangitsa kuti pakhale kuphwanya ntchito za kukonza kwawo kapena kuchotsa zinthu zomwe ziwonongeka. Ndipo zakudya zake zonse ndi gawo limodzi la mankhwala a gout ndi njira yolepheretsa matendawa kapena kufalikira kwa matendawa, makamaka ngati pali chibadwa chamtsogolo kapena zina zothandiza pakukula kwa kutupa kwa gouty.
Matenda amtundu wakuthupi monga chifukwa cha gout
Gulu la ma enzymes, mapuloteni omwe amathandiza njira yoyeretsa purine, amatsimikizika ndi kupezeka kwa majini ena amtundu wa munthu. Panthawi ya Fermentopathy, thupi limalephera kupanga ma enzyme okwanira kuti athandizire kaphatikizidwe, pokonza mankhwala osiyanasiyana. Pakakhala mapuloteni enieni omwe amayang'anira purine processing ndi uric acid excretion, kuchuluka kwa poizoni wamagazi m'magazi kumaonjezera, komwe kumayambitsa kukula kwa gout. Chipembedzo choterechi chimakhala chobadwa nacho ndipo chimachokera kwa makolo kupita kwa ana. Nthawi zambiri, vuto la enzyme, lomwe limayambitsa matenda a gout, ndi gawo limodzi la majini a metabolic, omwe amachititsanso kuti azitha kunenepa kwambiri, matenda ashuga, matenda oopsa, komanso Hyperlipidemia.
Njira zopangira matendawa
The etiology yowonetsera zowawa mu minofu yaularular ndi periarticular imayang'aniridwa mothandizidwa ndi zida zothandizira kuzindikira. Magawo omwe akhudzidwa amayesedwa pogwiritsa ntchito njira za ultrasound, computer tomography, radiography, komanso maphunziro a scintigraphic ogwiritsa ntchito intravenous technetium pyrophosphate. Njira yotsirizayi imagwira bwino ntchito kumapeto komanso koyambirira kwa matendawo. Pa gawo loyambirira la gout, ina, njira zodziwika bwino zothandizira popanga matendawa sizothandiza kwenikweni, chifukwa ndi gout poyambira koyambirira kwa matendawa, zizindikiro zowonongeka za ziwonetsero zam'mimba komanso periarticular zimakhala zopanda tanthauzo ndipo sizingatheke kuzindikira njira zambiri zodziwonera. Komabe, kugwiritsidwa ntchito kwawo kumalola ndi kulondola kwakukulu kusiyanitsa kukula kwa nyamakazi ya gouty ndi mitundu ina ya matenda amitsempha.