Gentamicin jakisoni: malangizo ogwiritsira ntchito

Gentamicin sulfate ili m'gulu la aminoglycosides, ali ndi mawonekedwe osiyanasiyana, kukhala antiotic bactericidal.

Ziwonetserozo zimawonjezera ntchito yolimbana ndi mabakiteriya a gram-negative aerobic: Shigella, E. coli, Salmonella, Enterobacter, Klebsiella, Protein, Pseudomonas aeruginosa. Gentamicin imagwiranso ntchito motsutsana ndi staphylococci (ngakhale omwe amalimbana ndi maantibayotiki ena, penicillin), ena a streptococci.

Osagwirizana ndi meningococcus ya mankhwala, wotupa treponema, mitundu ina ya streptococci, anaerobic bacteria.

Zisonyezero zogwiritsira ntchito Gentamicin

Gentamicin mogwirizana ndi malangizo amakonzekera zotere:

• kwamikodzo: cystitis, urethritis, pyelonephritis,
• kupuma thirakiti: empyma, mapapo, zotupa, chibayo,
• matenda opatsirana: poizoni wamagazi, zotupa za peritoneal,
• khungu: dermatitis, angapo purulent kutupa, trophic zilonda, amayaka.

Malangizo a Gentamicin

Kugwiritsa ntchito Gentamicin kumachitika bwino kwambiri mukazindikira tanthauzo la microflora yomwe idayambitsa matendawa.

Malangizo akuwonetsa kuchuluka kwa mankhwala

• ndi matenda a kwamkodzo thirakiti la achinyamata opitirira 14l. ndipo kwa akulu, mlingo umodzi ndi 0,4 mg wa kilogalamu imodzi ya kulemera kwa thupi, ndi mlingo wa tsiku ndi tsiku wa 0.8-1.2 mg pa kilogalamu ya kulemera kwa odwala.
• Ndi sepsis ndi matenda ena owopsa, mlingo umodzi ndi 0.8-1 mg pa kilogalamu, ndipo tsiku ndi tsiku ndi 2.4-3.2 mg.

Mulingo waukulu ndi 5 mg pa kilogalamu patsiku.

Ana ochepera zaka 14 Gentamicin sulfate amalembedwa pokhapokha akuwonetsa.

Mlingo wa tsiku ndi tsiku wa makanda ndi akhanda ndi 2-5 mg pa kilogalamu iliyonse. Ana ochokera 1-5l. sankha 1.5-3.0 mg pa kilogalamu, ana malita 6-14. - 3 mg pa kilogalamu.

Mlingo waukulu wa Gentamicin wa ana amisinkhu yosiyanasiyana ndi 5 mg / kg / tsiku.

Mlingo wa tsiku ndi tsiku umagawidwa pawiri kapena katatu. Maphunzirowa, pafupifupi, amatha masiku 7-10. Gentamicin jakisoni amapatsidwa masiku atatu mkati, ndipo atatha amapangira jakisoni wa mu mnofu.

Kwa makonzedwe a intramuscularly, Gentamicin sulfate imagwiritsidwa ntchito ngati njira yokhazikitsidwa kapena 2 ml ya kuchepetsedwa. wosalala madzi ufa. Ngati jakisoni wamkati wa Gentamicin, mutha kugwiritsa ntchito njira yokonzedwa yokonzedwa kale.

Gentamicin kirimu kapena mafuta amagwiritsidwa ntchito pochotsa zotupa pakhungu, folliculitis, furunculosis. Nthawi yomweyo madera omwe akukhudzidwawo amamwetsedwa ndi awiri kapena atatu r / tsiku kwa sabata limodzi kapena awiri.

Ndi conjunctivitis, keratitis, matenda ena opatsirana amaso, madontho a Gentamicin amagwiritsidwa ntchito - atatu mpaka anayi r / tsiku.

Zotsatira zoyipa

Kugwiritsidwa ntchito kwa Gentamicin kumatha kuyambitsa zotsatirazi: kusanza, nseru, hyperbilirubinemia, kuchuluka kwa hepatic transaminases, proteinuria, michereuria, oliguria, kulephera kwa impso, kupweteka kwa mutu, kusowa kwa makutu, kugona, kugontha, kusokonezeka kwa mitsempha, chotupa, malungo, kuyabwa, edema ya Quincke (kawirikawiri).

Contraindication

Malangizo a Gentamicin akuwonetsa kuti kugwiritsidwa ntchito kwake ndikotsutsana ngati wodwalayo ali ndi hypersensitivity ku mankhwala onse a gulu la aminoglycoside.

Komanso, Gentamicin sagwiritsidwa ntchito ngati matenda amitsempha yama mtima, kukhudzika kwamphamvu kwa impso, kutenga pakati, kuyamwa, uremia.

Gentamicin: mitengo pamafakitale apakompyuta

Gentamicin 40 mg / ml yankho la kulowa mkati ndi mu mnofu makonzedwe a 2 ml 10 ma PC.

Gentamicin 40 mg / ml yankho la kulowa mkati ndi mu mnofu makonzedwe a 2 ml 10 ma PC.

Gentamicin 40 mg / ml yankho la kulowa mkati ndi mu mnofu makonzedwe a 2 ml 5 ma PC.

GENTAMICIN 40 mg / ml 2 ml 10 ma PC. yankho la mtsempha wa magazi ndi mu mnofu makonzedwe

GENTAMICIN 40 mg / ml 2 ml 10 ma PC. yankho la mtsempha wa magazi ndi mu mnofu makonzedwe

Mafuta a GENTAMICIN 0,1% 15g ogwiritsa ntchito kunja

Zambiri zokhudzana ndi mankhwalawa ndizofanana, zimaperekedwa pazidziwitso ndipo sizilowa m'malo mwa malangizo ovomerezeka. Kudzipatsa nokha mankhwala kuopsa!

James Harrison wazaka 74 yemwe amakhala ku Australia amakhala wopereka magazi pafupifupi nthawi 1,000. Ali ndi mtundu wamagazi osafunikira, ma antibodies omwe amathandizira akhanda omwe ali ndi vuto lalikulu la magazi kukhala ndi moyo. Chifukwa chake, waku Australia adapulumutsa ana pafupifupi mamiliyoni awiri.

Pochezera pafupipafupi pakama pofufuta, mwayi wokhala ndi khansa yapakhungu umawonjezeka ndi 60%.

Madokotala a mano adapezeka posachedwa. Kalelo m'zaka za zana la 19, inali ntchito ya tsitsi wamba kuti akatulutse mano odwala.

Ku UK, kuli lamulo malinga ndi momwe dokotala wothandizira amatha kukanachita opaleshoni ngati atasuta kapena wonenepa kwambiri. Munthu ayenera kusiya zizolowezi zoipa, kenako, mwina, sangafunikire opareshoni.

Vibrator woyamba adapangidwa m'zaka za zana la 19. Adagwira ntchito pa injini yankhonya ndipo adapangira kuti azitsatira khungu la akazi.

Pali ma syndromes osangalatsa kwambiri azachipatala, monga kuphatikiza zinthu. M'mimba mwa wodwala m'modzi wodwala mania uyu, zinthu 2500 zakunja zidapezeka.

Caries ndimatenda ofala kwambiri padziko lonse lapansi omwe ngakhale chimfine sangathe kupikisana nawo.

Asayansi aku America adayesera mbewa ndipo adati madzi amadzi amalepheretsa kukula kwa atherosulinosis yamitsempha yamagazi. Gulu limodzi la mbewa limamwa madzi am'madzi, ndipo lachiwiri ndi madzi a mavwende. Zotsatira zake, zombo za gulu lachiwiri zinali zopanda ma cholesterol.

Ntchito yomwe munthu samakonda imakhala yovulaza psyche yake kuposa kusowa kwa ntchito konse.

Kuti tinene ngakhale mawu afupi komanso osavuta, timagwiritsa ntchito minofu 72.

Chiwindi chanu chikasiya kugwira ntchito, imfa imatha pakatha tsiku limodzi.

Ngati mumamwetulira kawiri kokha patsiku, mutha kuchepetsa kuthamanga kwa magazi ndikuchepetsa chiopsezo cha matenda a mtima ndi stroko.

Pa moyo, munthu wamba amapanga miyala yocheperako yoposa awiri.

Malinga ndi asayansi ambiri, mavitamini zovuta ndizothandiza kwa anthu.

Munthu wophunzira sakhala wokonzeka kutenga matenda aubongo. Ntchito zaluso zimathandizira kuti pakhale ziwalo zina zowonjezera kulipirira odwala.

Malinga ndi ziwerengero, pafupifupi 80% ya akazi ku Russia amadwala bakiteriya. Monga lamulo, matenda osasangalatsa awa amatsatiridwa ndi kutuluka koyera kapena imvi.

Kutulutsa mawonekedwe ndi kapangidwe kake

Njira yothetsera makonzedwe a makolo Gentamicin ndi madzi omveka, opanda khungu. Muli ma ampoules a 2 ml. Mbale umodzi uli ndi 80 mg ya hamamicin sulfate monga chinthu chachikulu chogwiritsa ntchito. Ampoules amawaika matuza mu kuchuluka kwa zidutswa 10. Phukusi la makatoni limakhala ndi chovala chimodzi cholumikizira ndi malangizo ogwiritsira ntchito mankhwalawa.

Mlingo ndi makonzedwe

Gentamicin Injection Solution imathandizira kudzera m'mitsempha kapena m'mitsempha. Mlingo wovomerezeka tsiku lililonse wa mankhwalawa ndi 3-5 mg / kg kulemera kwa thupi, wogawika majakisoni atatu. Njira yodziwika bwino ya mankhwalawa ndi masiku 7-10, ngati kuli kotheka, dokotala amatha kuwonjezera mankhwala opha antibayotiki kwa masiku angapo. Palinso chiwembu chowongolera njira ya Gentamicin mu njira yokwanira 160 mg (2 ampoules) kamodzi patsiku, pakapita masiku 7-10. Mu matenda oopsa, mankhwalawa 240 mg wa antiotic (3 ampoules) imodzi amaperekedwa kamodzi. Kwa ana opitirira zaka 2, mlingo wa tsiku ndi tsiku wa mankhwalawa ndi wofanana ndi akulu - 3-5 mg / kg thupi. Kwa ana obadwa kumene kapena osabereka, tsiku lililonse mlingo 2-5 mg / kg wa thupi, umagawidwa majakisoni awiri. Kwa ana ochepera zaka ziwiri, mlingo womwewo umagawidwa majakisoni atatu. Ndi kulephera kwa aimpso, kuchuluka kwa yankho la Gentamicin kumakonzedwa, kutengera kutha kwa kuchepa kwa ntchito ya impso.

Zotsatira zoyipa

Kugwiritsa ntchito yankho la makina a makolo a Gentamicin kungayambitse kukulitsa zotsatira zoyipa kuchokera ku ziwalo zosiyanasiyana ndi machitidwe:

• Matumbo a pakhungu - nseru, kusanza, chopondapo chopanda.
• Mitsempha yam'mimba - mutu, kugona, chizungulire.
• Mchitidwe wamchiberekero - proteinuria (mawonekedwe a mapuloteni mumkodzo), cylindruria (mawonekedwe a mabowo am'mimbamu mu mkodzo ngati masilindala), kukula kwa kulephera kwa impso.
• Mafuta ofiira a m'mafupa ndi magazi m'magazi - kuchepa magazi (kuchepa kwa hemoglobin ndi maselo ofiira am'magazi), granulocytopenia (kutsika kwa kuchuluka kwamitundu ina yama cell oyera m'magazi, makamaka neutrophils ndi eosinophils).
• Ma biochemical labotale magawo - kuwonjezeka kwa ntchito ya chiwindi transaminase enzymes (AST, ALT), yomwe imawonetsa kuwonongeka kwa hepatocytes (ma cell a chiwindi).
• Momwe thupi limagwirira - mawonekedwe a chotupa pakhungu, kuyabwa kwake, ming'oma (chizolowezi chokhala ndi chotupa komanso chotupa chomwe chimawoneka ngati kutentha kwa nettle). Momwe thupi lawo limakhudzidwa ndi mawonekedwe a angioedema Quincke edema (kutupa kwambiri pakhungu ndi minyewa yofinya kumaso, ziwalo zakunja) kumayamba kupezeka kangapo. Pali milandu yodziwika ya kukhazikika kwa anaphylactic kugwedezeka (kuchepa kwapang'onopang'ono kwa kuchuluka kwa kuthamanga kwa magazi ndi ziwalo zingapo).

Pazifukwa zoyipa, kuyendetsa gentamicin yathetsedwa.

Malangizo apadera

Musanayambe chithandizo ndi Gentamicin jekeseni, malangizo apadera ayenera kukumbukiridwa ponena za momwe amagwiritsidwira ntchito, omwe amaphatikizapo:

• Kuwonetsedwa kwa kuwonongeka kwa ntchito kwa impso kapena minyewa yam'maso kumafuna kusiya kwa mankhwalawo.
• Mosamala, Gentamicin Injection imagwiritsidwa ntchito mwa ana aang'ono.
• Ngati kuli kofunika kuperekera mankhwalawa kwa mayi woyamwitsa, mwanayo amamugulitsa kuti am'thandize kudya mkaka wosinthika kwa nthawi yonse yogwiritsa ntchito yankho la Gentamicin.
• Munthawi ya chithandizo ndi Gentamicin jakisoni yankho, nthawi yowunika ma piritsi a michere yayikulu yogwira ntchito ya chiwindi ndi impso ndiyofunikira.
• Poyang'aniridwa ndi achipatala pafupipafupi, mankhwalawa amaperekedwa kwa odwala omwe amakhala ndi kuchepa kwa magazi m'thupi (minyewa) ndi myasthenia gravis (kufooka kwa minofu).
• Mankhwala amatha kuyanjana ndi mankhwala a magulu ena a pharmacological, makamaka ndi kuphatikizika kwa loop diuretics (okodzetsa), ndizotheka kuwonjezera zovuta zake pa impso.
• Mankhwala samakhudza chidwi cha anthu komanso kuthamanga kwa zochitika zama psychomotor.

Patsamba lamankhwala, jekeseni ya Gentamicin imaperekedwa ndi mankhwala. Odziyimira pawokha kapena pa upangiri wachitatu wothandizidwa ndi mankhwalawa osavomerezeka.