Liptonorm - malangizo atsatanetsatane ogwiritsira ntchito, kuyanjana ndi mankhwala ena

Mankhwala Liptonorm ndi mankhwala omwe ali a lipid-kuchepetsa mankhwala a pharmacological gulu la statins.

Mankhwalawa amatha kutsitsa cholesterol yamagazi ambiri.

Pakuchepetsa mulingo wa cholesterol m'mwazi, mankhwala a Liptonorm amalepheretsa kukula kwa matenda amitsempha yamagazi - systemic atherosclerosis, komanso ma pathologies ena a mtima ndi dongosolo la magazi.

Amachepetsa cholesterol index chifukwa cha hypercholesterolemia.

Mankhwala Liptonorm amapangidwa mwa mawonekedwe a piritsi. Mapiritsiwo ali mu kanema wophatikizira wa hue yoyera ndi mawonekedwe awiri mbali zonse, ndikuphwanya piritsi ndi yoyera. Mapiritsiwo adapangira pakamwa.

Wopanga amapanga mankhwala okhala ndi mankhwala osokoneza bongo a atorvastatin - mamilimita 10.0 piritsi limodzi, mamilimita 20.0.

Mapiritsiwo amawaika matuza m'mapiritsi 7, 10 ndi 14:

• Makatoni okhala ndi malangizo okhala ndi matuza 1 (ma 7 ma PC),
• Makatoni awiri matuza (ma 7 ma PC) okhala ndi mawu,
• Makatoni okhala ndi malangizo okhala ndi matuza 1 (ma PC 10),
• Makatoni awiri matuza (ma PC 10) okhala ndi mawu,
• Makatoni okhala ndi malangizo okhala ndi matuza atatu (ma PC 10),
• Makatoni okhala ndi malangizo ogwiritsira ntchito 1 matuza (14 ma PC),
• Phukusi la makatoni 2 matuza (ma 14 ma PC) okhala ndi mawu.

Kuphatikiza pa gawo logwira ntchito la atorvastatin, mankhwala a Liptonorm amaphatikizanso zina:

• MCC
• Ma molekyulu a Lactose
• Calcium calcium
• Mtanda wa Crosscarmellose
• Stearate yama mamolekyulu a magnesium,
• Chombo Twin-80,
• Titanium diayoni,
• Gawo lake ndi polyethylene glycol.

Mankhwala

Mankhwala a Liptonorm ndi HMG-CoA reductase inhibitor yomwe imalepheretsa kusintha kwa enzyme A kukhala gawo la mevalonate, lomwe limachepetsa kupanga ma cellids ndi cholesterol m'magazi a plasma.

Kuphatikiza ndi zoletsa, Liptonorm imayendetsa ma receptors mu maselo a chiwindi omwe amayankha ma cell ochepa osachulukitsa lipoproteins. Ma receptor amenewa amatenga ma lipids otsika kwambiri ndikuwonjezera mphamvu zawo.

Kukhazikika pamatumbo amkati mwa choroid, ma lipoprotein otsika kwambiri, omangika kwa mamolekyulu a calcium, amapanga cholembera cha atherosclerotic m'mitsempha, chomwe chitha kuyambitsa matenda akulu m'thupi la munthu.

Zotsatira za mankhwala a Liptonorm pamaselo a chiwindi zimayambitsa kukhudzidwa kwa magazi:

• Mamolekyu a cholesterol yathunthu pakuchepa kwa magazi (index ya OX),
• Mndandanda wa magawo ochepa a lipoproteins (LDL) amachepa,
• Kuchepa kwa kachigawo kochepa kwambiri ka lipids (VLDL) kumachepetsedwa,
• Mndandanda wa lipoproteins wapamwamba kwambiri (HDL) ndi apoprotein A ukuwonjezeka
• Kukhalapo kwa mamolekyulu a triglyceride kumachepetsedwa.

Komanso, Liptonorm imatulutsa mphamvu pakhungu, ndipo imasintha kapangidwe ka magazi. Kuletsa kuphatikiza kwa isoprenoids kumachitika. Izi ndi zina mwa zinthu zomwe zimapangitsa kuti maselo azitha kusintha mkati.

Zotsatira zochizira zimayamba kuonekera, patatha masiku 14 atangoyang'anira, mphamvu kwambiri ya atorvastatin m'thupi imawonekera pambuyo pa chithandizo cha mwezi umodzi.

Malangizo Mankhwala ku nkhani zake ↑

Pharmacokinetics

Nthawi ya ntchito yayikulu ndikuyang'aniridwa mu madzi am'magazi a chinthu chachikulu ndikuchokera kwa maola 1 mpaka 2 ndipo zimatengera nthawi yomwe mumamwa mapiritsi, komanso mtundu wa wodwala.

Mankhwalawa ali ndi bioavailability wotsika - osakwana 12,0%.

Hafu ya moyo wa gawo limodzi la rosuvastatin limayambira maola 8 mpaka 12 maola. Zimatengera mlingo womwe umatenge tsiku lililonse.

Njira yochotsa kwathunthu kachigawo kuyambira mthupi mpaka maora 18 mpaka 30. Kuchulukitsa ndizochepa kwambiri ndipo ndizochepa kuposa 1.0%

Kutuluka kwa chigawo cha atorvastatin kudzera pa bile ndi ndowe ndi mkodzo.

Zisonyezero zakugwiritsa ntchito Liptonorm

Fotokozani za Liptonorm mankhwala zochizira izi:

• Pulogalamu yayikulu ya heterozygous ndi homozygous yopanda cholowa m'mabanja hypercholesterolemia,
• Hypercholesterolemia wosakanikirana,
• Matenda a dysbetalipoproteinemia monga chowonjezera chakudya,
• Matenda a hypertriglyceridemia.
• Kuti muchepetse kupita patsogolo kwa systemic atherosulinosis, komanso kuphatikiza ndi zakudya.

Mankhwala enanso, Liptonorm, amathandizidwa kupewetsedwa pambuyo pobaya ndi pambuyo pake.

Contraindication

Ngati mankhwala, contraindations ntchito:

• Ndi chidwi chachikulu cha thupi ku atorvastatin ndi zina zowonjezera,
• Kuchulukitsidwa kwa ma transaminase,
• Kulephera kwa chiwindi
• Amayi panthawi yoyembekezera
• Mukamayamwitsa.
• Pakakhala kulera kwabwino mwa amayi,
• Ndi matenda a impso,
• Ana a zaka mpaka 18.

Njira yapadera yoperekera mankhwala ndiyomwe imafunikira ma pathologies oterowo:

• Ndi hepatic pathologies - chiwindi, cirrhosis maselo a chiwindi,
• Kuphwanya muyezo wamagetsi,
• Ndi kuphwanya kwa ziwalo za endocrine,
• Pa uchidakwa wambiri,
• Ndi index yotsika magazi,
• Ndi matenda opatsirana m'thupi,
• Chifukwa cha kugwidwa koopsa,
• Mu nthawi ya postoperative ndi nthawi yovuta.

Zotsatira zoyipa

Momwe mungamwe mankhwalawo?

Malinga ndi malangizo ochokera kwa wopanga mankhwalawa Liptonorm, zikuwoneka kuti muyenera kumwa mapiritsiwo mkati, osadzaza, komanso kumwa ndi kuchuluka kwa madzi. Palibe zonena za nthawi, koma ziyenera kutengedwa nthawi yomweyo.

Mfundo za njira y kumwa mankhwalawa ndi kuchuluka kwa mankhwalawa:

• Asanayambe chithandizo ndi Liptonorm, wodwalayo ayenera kudya zakudya zotsitsa cholesterol index.
• Njira yonse yochizira iyenera kuphatikizidwa ndi zakudya,
• Mlingo wake umasankhidwa ndi dokotala payekha komanso mogwirizana ndi zomwe zikuwonetsedwa ndi milomo.
• Mlingo woyambirira wa mankhwalawa ndi mamiligamu 10.0, kamodzi patsiku,
• Onjezani mlingo kapena mankhwalawa, ndi adokotala okhawo omwe amatha kumwa ma analog atatenga mapiritsi mwezi umodzi,
• Mlingo wabwino kwambiri tsiku limodzi ndi mamiligalamu 80.0,
• Mulingo woyenera kwambiri wa mankhwalawa, tikulimbikitsidwa kuti tizichita chipatala ndikuwunika ma hepatic transaminases ndi cholesterol index.
• Odwala okalamba safuna kusintha kwa mlingo.

Kuchita ndi mankhwala ena

Ndi munthawi yomweyo makonzedwe a mankhwala a cyclosporine, myopathy imachitika komanso kuwonjezeka kwa gawo la atorvastatin m'magazi, myopathy imapezekanso pakudya Erythromycin.

Mankhwala Colestipol, akagwiritsidwa ntchito limodzi ndi Liptonorm, amathandizira kutsitsa kwa milomo ya lipid.

Ngati mutenga Digoxin ndi Liptonorm nthawi yomweyo, ndiye kuti pakuwonjezeka kwa kuchuluka kwa Digoxin.

Ngati Digoxin ikufunika panthawi ya chithandizo ndi Atorvastatin, ndiye kuti adokotala amayenera kuyang'anira kuchuluka kwa mankhwalawa onse m'magazi.

The kuchuluka kwa njira zakulera mu thupi kumawonjezera ndi limodzi makonzedwe a Liptonorm ndi mankhwala Ethinyl estradiol, komanso mankhwala Norethindrone.

Mukatenga Liptonorm ndi Warfarin palimodzi, nthawi ya prothrombin imachepetsedwa ndipo iyenera kuyang'aniridwa pafupipafupi.

Sitikulimbikitsidwanso kutenga madzi a Liptonorm ndi msuzi wa mphesa. Madzi amachulukitsa kuchuluka kwa ma cell a plinma, ndipo amayenera kutayidwa kwa nthawi yonse ya mankhwalawo.

Kuchita ndi mankhwala ena ku nkhani zake ↑

Analogs of Liptonorm

• Mankhwala Liponorm,
• Mankhwala Atoris,
• Atorvox analogue,
• Mankhwala Anvistat,
• Mankhwala a Atocord
• Njira Atomax,
• Mankhwala a Atorvastatin
• Mankhwala Liprimar,
• Mankhwala Tulip,
• Lipon Remedy,
• Mankhwala ndi vazator.

Pomaliza

Kugwiritsa ntchito kwa mankhwala Liptonorm kuti muchepetse cholesterol yamagazi, kumakhala kokhako malinga ndi zomwe dokotala wakulembani, ndipo musadzimvere.

Ndikofunikira kumwa mankhwalawa limodzi ndi zakudya, zomwe kuwonjezera pa achire zimathandizanso kuti wodwala azitha kuchepa.

Svetlana wazaka 47: Adotolo adandiuza Liptonorm mwezi watha, chifukwa cha triglycerides okwera m'magazi. Izi zisanachitike, ndinadutsa maphunziro a miyezi 3, koma TG sinachepe.

Patatha mwezi umodzi ndikupeza Liptonorm, zizindikiro zanga zonse za lipid zidabweranso, ndipo pofuna kuphatikiza zochizira, ndimamwa mapiritsi ena mwezi.

Illarion, zaka 70: mankhwalawa atherosclerosis ndinamwa mapiritsi ambiri, ena amatsitsa cholesterol yanga, koma anali okwera mtengo kwambiri kuti agwiritse ntchito mosalekeza.

Anzanu otsika mtengo sanandithandizire. Adotolo adandiuza Liptonorm. Ndakhala ndikumwa kumwa kwa miyezi iwiri tsopano. Zotsatira za mankhwalawa ndi zabwino, ndipo mtengo wake si wokwera mtengo kwa ine.