Kodi mankhwala a Tricor ndi malangizo ake ndi ati?

Tricorr ndi dzina la mankhwalawa zomwe zimapangitsa kuti azindikire kwa ogula ndipo amagwiritsidwa ntchito kugulitsa zinthu. Dzinalo losavomerezeka padziko lonse lapansi ndi Fenofibrate.

Ili ndi magawo awiri ofunikira.

Choyamba ndi kuchepa kwa kuchuluka kwamafuta amwazi wamagazi monga cholesterol ndi triglycerides, zomwe zimachulukirachulukira zomwe zimathandizira kwambiri kukulitsa kwa matenda amtima kuposa kukulitsa aliyense payekhapayekha. Mothandizidwa ndi fenofibrate, mafutawa amasungunuka mwachangu ndikuchotsedwa m'thupi. Zowona, kuchuluka kwa kuchepa sikofanana: cholesterol yathunthu imachepetsedwa ndi kotala, ndipo ndende ya triglycerides imatsitsidwa. Awa ndi mankhwala omwe amatha kuthetseratu zomwe zimapezeka mu cholesterol zomwe siziri m'matumba, mwachitsanzo, mu tendons.

Chachiwiri ndi kuchepa kwa milingo ya fibrinogen, maziko a magazi. Zowonjezera kuchuluka kwa mapuloteni awa zimawonetsa njira zotupa mthupi, hypothyroidism yoopsa, ndi matenda ena akuluakulu. Fenofibrate imachepetsa kuchuluka kwake, potero kumawonjezera kuchuluka kwa magazi (kuchepetsedwa).

Kutulutsa fomu, mtengo

Mankhwala amafalitsidwa monga mapiritsi amkamwa. Mtengo wa Tricor umadalira kuchuluka kwa chinthu chomwe chimagwira piritsi limodzi. Mtengo wapakati wamankhwala ukuwonetsedwa pansipa.

Kuphatikizika ndi mankhwala

The yogwira ndi micenized fenofibrate mu kuchuluka kwa 0,145 kapena 0,160 mg. Zowonjezera ndi sodium laurisulfate, sucrose, lactose monohydrate, crospovidone, aerosil, hypromellose, etc.

Fenofibrate ndi chinthu chochokera ku ma fiber angapo. Ili ndi lipid-yotsitsa chifukwa cha kuyambitsa kwa RAPP-alpha. Mothandizidwa ndi iye, njira ya lipolysis imatheka, kupanga ma apoproteins A1 ndi A2 kumatheka. Nthawi yomweyo, kupanga apoprotein C3 ndi olepheretsa.

The kuchuluka kwa lipids mu madzi am`magazi amachepetsa chifukwa cha njira yowonjezera yawo. Munthawi yonse ya chithandizo, pali kuchepa kwa mafuta a cholesterol, triglycerides, ndipo chiwopsezo cha kupangika kwa zosowa zamphamvu za zinthu izi zimachepezedwanso.

Pambuyo patatha maola 2-4 mutamwa piritsi, kuchuluka kwa mankhwalawa kumawonedwa. Komanso, kuphatikiza kwawo kwambiri kwamankhwala kumasungidwa mwa odwala onse mosasamala nthawi yonse ya mankhwala. Mankhwala ambiri amatsitsidwa kudzera mu impso. Kuchotsa kwathunthu kumadziwika pambuyo masiku 6.

Zizindikiro ndi contraindication

Tricor amatchulidwa kuti azisonyeza zina:

• hypercholesterolemia, yomwe singathetsedwe ndi zakudya,
• hypertriglyceridemia,
• hyperlipoproteinemia yomwe idatulukira motsutsana ndi maziko a ma pathologies ena (yachiwiri mawonekedwe).

Contraindication pa mankhwala a Trikor akuphatikiza:

• kulephera kwa chiwindi
• Hypersensitivity zigawo zikuluzikulu za mankhwala kapena ziwombolo kwa iwo,
• matenda a ndulu,
• Kulephera kwaimpso komwe kumachitika motsutsana ndi kobadwa nako galactosemia,
• matenda a chiwindi.

Tricor, monga lamulo, silinafotokozedwenso kwa akazi panthawi yapakati komanso mkaka wa m'mawere. Ngati pakufunika kugwiritsa ntchito kwake, ndi dokotala yekhayo amene angadziwitse mankhwalawo, atayerekezera zabwino ndi zoopsa zomwe zingachitike. Komanso, mankhwalawa amaphatikizidwa ndi ana osakwana zaka 18.

Malangizo apadera

Ndi matenda a hepatic pathologies, Tricor ndi mankhwala si mankhwala. Amagwiritsidwa ntchito mosamala kwambiri odwala omwe ali ndi vuto la hypothyroidism. Pa mankhwala, ndikofunikira nthawi ndi nthawi kuyezetsa magazi a biochemical pamlingo wa mahomoni a chithokomiro.

Kwa odwala omwe ali ndi chidakwa chachikulu, mankhwala amatha kuperekedwa pokhapokha ngati akufunika kwambiri. Zomwezo zikugwiranso ntchito kwa odwala omwe akuchita chithandizo cha HMG-CoA reductase. Kuchulukitsa chidwi kuchokera kwa dokotala kumafunikira kwa odwala omwe ali ndi vuto lobadwa nawo kapena losakhazikika minofu, komanso anthu omwe amatenga mankhwala otulutsa pakamwa.

Kuchita ndi mankhwala ena

Mukamagwiritsa ntchito mapiritsi a Tricor, ayenera kukumbukiridwa kuti sayenera kuphatikizidwa ndi magulu ena a mankhwala. Nthawi zina, kugwiritsa ntchito mankhwala munthawi yomweyo limodzi ndi mankhwala ena kungayambitse zotsatira zosafunikira ndi matenda:

• Kugwiritsidwa ntchito kwa Tricor motsatana ndi ma anticoagulants kwambiri kumawonjezera mwayi wokhetsa magazi.
• Mankhwalawa sayenera kuphatikizidwa ndi cyclosporins, chifukwa izi zimapangitsa kuti ntchito yaimpso izipuwala.
• Ndi makonzedwe apakati a Tricor okhala ndi zoletsa za HMG-CoA reductase, pali mwayi wokhala ndi rhabdomyolysis.
• Zotsatira za sulfonylureas kuphatikiza ndi mankhwala omwe amafunsidwa zimayambitsa kuchuluka kwa hypoglycemic.
• Tricor imawonjezera mphamvu ya acenocoumarol.

Zochita Zosiyana ndi Zizindikiro Zambiri

Zotsatira zoyipa zimachitika kawirikawiri. Amatha kuwoneka ngati:

• kupweteka m'dera la epigastric,
• nseru
• kutaya tsitsi
• kusanza
• Photophobia
• kukula kwa kapamba kapamba,
• kusowa pogonana
• kutsegula m'mimba
• chisangalalo
• kuchuluka kwa hemoglobin,
• mutu
• chitukuko cha chiwindi
• venous thromboembolism,
• kuchuluka kwa ndende ya urea,
• kuyabwa m'thupi,
• kufooka kwa minofu
• pulmonary embolism
• kuchuluka kwa maselo oyera
• urticaria.

Ngati mukukumana ndi zovuta zotere, kapena ngati mukukayikira kuti chitukuko cha matenda amodzi omwe tatchulawa, muyenera kufunsa dokotala.

Milandu ya bongo ndi Tricor odwala sanalembedwe. Ngati matendawo apezeka munthawi yogwiritsira ntchito mankhwalawa muyezo waukulu, siyani kumwa mapiritsi. Palibe ma antidoteti enieni othetsa Zizindikiro za bongo. Pankhaniyi, chithandizo chamankhwala chimachitika.

Ma analogu

Sizotheka nthawi zonse kuchitira hyperlipidemia kapena hypercholesterolemia mothandizidwa ndi mankhwala Tricor. Zikatero, adotolo atha kukulemberani zakumwa zina zotchipa za mankhwalawo. Gome limangowonetsera otchipa a Tricor.

Uwu si mndandanda wathunthu wa mankhwala omwe angapangidwe m'malo mwa Tricor. Komabe, mankhwala ena ali ofanana ndi mankhwalawa omwe amangofunsidwa pa code ya ATC 4 yokha. Komanso, kuchuluka kwazomwe zimagulitsa zamankhwala zimakhala ndi zotsatira zofananira, ndipo zimakhala ndi zofananira zomwe zimagwiritsidwa ntchito, komabe, sizikuwonetsedwa mwachindunji ndi Tricor.

Sikoyenera kudzisankhira pawokha posankha mankhwalawo. Ngakhale mutakhala ndi zovuta, zizindikiro za bongo zikupezeka, muyenera kuonana ndi dokotala. Ndi iye yekhayo amene angasankhe chida chothandiza chomwe chitha kusintha Tricor.

Ndemanga za madokotala ndi odwala

Ndemanga za odwala za Tricor ndizosiyana. Madokotala amafotokozanso malingaliro osiyanasiyana pankhani y kumwa mankhwalawa:

Vasily Fedorov, wazaka makumi atatu ndi zisanu ndi zitatu: Adatembenukira kwa gastroenterologist-zakudya, adandiuza kuti ndidye zakudya. Anatsatira kwa nthawi yayitali kwambiri, koma sanalandire zotsatira zomwe ankayembekezera.

Polumikizana ndi othandizira, adalandira kutumizira kuti awunikire mbiri ya lipid. Cholesterol chinapita pamlingo - 7.8 mmol. Dokotala adamuuza Tricor. Ndidamwa mankhwalawa kwa nthawi yayitali, koma zotsatira zake zidadziwika pambuyo masiku ochepa. Pang'onopang'ono, kulemerako kunayamba kubwerera ku zachilendo, komanso zizindikiro zowunikira. Ndipo palibe mavuto! Ndikusangalala ndi mankhwalawo. ”

Elena Savelyeva, wazaka 48: “Ndili ndi matenda ashuga, omwe adapezeka zaka 20 zapitazo. Kuyambira pamenepo, cholesterol yakhala "ikulumpha" mosalekeza. Adokotala anga a endocrinologist adandipangira makapisozi a Tricor. Pambuyo pa mlingo woyamba, panali vuto lodana ndi mseru komanso mutu.

Ndidayenda tsiku lachiwiri kuti nditenge piritsi lina. Tithokoze Mulungu kuti sindinawone “zotsatila” zilizonse. Anamaliza maphunziro athunthu, ndipo ndikuthokoza kwambiri kwa dokotala pondipatsa mankhwala. Ndili wokondwa ndi mankhwalawo - cholesterol yachepa, milomo ya lipid yabwerera mwakale. ”

Irina Slavina, dokotala wamkulu: “Sindipereka mankhwala kwa odwala anga nthawi zambiri monga madokotala ena. Nthawi zambiri, odwala amadandaula za kusanza, nseru, chizungulire. Zachidziwikire, zizindikiro zonsezi ndizogwirizana, koma simungathe kutseka nawo.

Malingaliro anga: musanatembenukire ku ma fibrate, ndikofunikira kuti mupereke mankhwala kwa odwala. Osachepera, ili ndiye njira yanga yothandizira matenda a hypercholesterolemia kapena hyperlipidemia m'magulu osiyanasiyana a odwala. "

Tricor ndi mankhwala othandiza kwambiri omwe amathandiza kutsika kwa lipids ndi cholesterol. Zotsatira zake zidawunikira m'maiko ambiri padziko lapansi - USA, Europe, ndi ena.

Koma, poganizira kuwunika kwamankhwala ambiri omwe amapezeka pa intaneti, mankhwalawo sakhala "opanda mawonekedwe" nthawi zonse. Anthu ambiri amakumana ndi zovuta zoyipa zomwe siziyenera kukhala maso. Kusinthasintha kosalekeza komwe kumagwiridwa ndi kutenga makapisozi kumafuna kuchotsetsa mankhwalawo, kapena kusinthana ndi mankhwala ena. Koma chisankhochi chimapangidwa ndi katswiri.

Kutulutsa mawonekedwe ndi kapangidwe kake

Kunja, mankhwalawa ndi phale lalitali, lomwe limayikiridwa ndi chipolopolo choyera ndi nambala ya "145" mbali imodzi ndikulemba "F" mbali inayo, ndikuyika mu masamba a zidutswa khumi kapena khumi ndi zinayi. Matumba amayikidwa m'mabokosi a makatoni ndalama kuchokera pa imodzi (yogwiritsidwa ntchito kunja) mpaka magulu atatu (zipatala). Malangizo ogwiritsira ntchito akuphatikizidwa pamenepo.

Piritsi lililonse limakhala ndi:

• gawo lomwe limapangidwa ndi fenofibrate yoyeserera ndi voliyumu 145,
• zinthu zina, kuphatikizapo sucrose, sodium lauryl sulfate, lactose monohydrate, crospovidone, microcrystalline cellulose, colloidal silicon dioxide, hypromellose, docusate sodium, magnesium stearate,
• chigoba chakunja chopangidwa ndi mowa wa polyvinyl, titanium dioxide, talc, soy lecithin, ganthan chingamu.

Pharmacological katundu ndi pharmacokinetics

Mankhwala omwe aperekedwa amachepetsa kuchuluka kwa lipoprotein otsika kwambiri komanso otsika kwambiri, ndikumakulitsa kuchuluka kwa lipoproteins yapamwamba. Amachepetsa kuchuluka kwakufupika ndi tinthu tating'onoting'ono ta lipoproteins, kuchuluka kwakukulu komwe kumawonetsedwa mwa anthu omwe ali ndi chiopsezo cha ischemia cha minofu ya mtima. Kafukufuku wachipatala amatsimikizira kuti fenofibrate qualitatively komanso mwachangu mokwanira amachepetsa kwambiri cholesterol, kuphatikiza ndi kuchuluka kwa triglycerides komanso kukhalapo kwa hyperlipoproteinemia.

Tricorr imathandiza kuthana ndi tendon ndi tubular papules.

Kugwiritsa ntchito fenofibrate kumawonekeranso kwa anthu omwe ali ndi vuto la ziwengo za lipid komanso kuchuluka kwa uric acid mthupi. Izi zimachitika chifukwa chakuti kuwonjezera pazowonjezera zake, zimathandizanso kulepheretsa kuchuluka kwa uric acid, zomwe zimapangitsa kutsika kwake ndi pafupifupi kotala .

Fenofibrate pokonzekera ili mu mawonekedwe a zigawo za nanoscale. Kugawika, imapanga fenofibroic acid, theka la moyo lomwe limachepera pang'ono patsiku - pafupifupi maola makumi awiri. Pafupifupi kwathunthu, umachoka m'thupi mkati mwa masiku asanu ndi limodzi. Kuchuluka kwazomwe zimapangidwa m'magazi zimawonedwa pambuyo pa awiri, nthawi yayitali maola anayi mutatha kugwiritsa ntchito. Ndi chithandizo chakanthawi, chimakhala chokhazikika, ngakhale wodwalayo atakhala ndi zina zomwe zimagwira ntchito mthupi.

Kukula kwa tinthu timene timagwira kumapangitsa kuti mankhwalawa azitha kugwiritsidwa bwino ntchito, mosasamala nthawi yomwe munthu adadya.

Zizindikiro zogwiritsidwa ntchito

Chiwopsezo chachikulu cha stroke kapena myocardial infarction (monga prophylactic).

Kukhalapo kwa mavuto azaumoyo monga kupitirira malire a cholesterol, matenda osakhazikika a mitsempha yamagazi ndi mawonekedwe a cholesterol pa iwo, matenda a mtima, kuchuluka kwambiri kwa lipids kapena lipoproteins m'magazi.

Hypercholesterolemia ndi hypertriglyceridemia kudzipatula kapena kusakaniza, ngati kusintha kwa zakudya, kuchuluka kwa zochita zamagalimoto ndi zochitika zina popanda kugwiritsa ntchito mankhwala sizinathandize.

Kulimbana ndi yachiwiri hyperlipoproteinemia, ngati chithandizo cha matenda oyambira chikuwonetsa zotsatira zabwino, koma palibe zotsatira za hyperlipoproteinemia palokha.

Contraindication

Mankhwalawa ali ndi contraindication okhwima, omwe amaletsa kugwiritsidwa ntchito kwake, komanso wachibale. Awiriwo amalola kuti agwiritsidwe ntchito moyang'aniridwa ndi achipatala ndikuwunikira nthawi ndi nthawi mayeso ena.

Tricor sangatchulidwe ngati wodwala ali:

• Hypersensitivity ku chinthu chachikulu yogwira kapena zinthu zake zina,
• kulephera kwa chiwindi
• kuphwanya kwambiri ntchito zonse za impso,
• kusintha kwa thupi pogwiritsa ntchito ma fiber kapena ketoprofen m'mbuyomu,
• matenda a gallbladder.

Kuyamwitsa ndikuphwanyaphwanya kwakanthawi kogwiritsa ntchito fenofibrate, popeza imalowa mkaka wa mayiyo kulowa m'thupi la mwana, yomwe siili yovomerezeka.

Mawonetseredwe a mziwopsezo pakugwiritsa ntchito mtedza (mtedza), soya kapena "abale" awo - maziko akukana.

Ngati phindu logwiritsa ntchito mankhwalawa ndilokulirapo kuposa chiwopsezo chomwe chitha, ndiye kuyang'aniridwa ndi dokotala nthawi zonse, zimaloledwa kuti ziwathandize odwala omwe ali ndi vuto la chiwindi ndi impso, opuwala chithokomiro, anthu omwe akudwala mowa, okalamba, odwala omwe ali ndi matenda amisempha. anatengera, munthawi ya mankhwala ndi mankhwala umalimbana ndi magazi, amayi apakati.

Mlingo ndi makonzedwe

Kumwa mankhwalawa ndikosavuta - piritsi limodzi kamodzi patsiku nthawi iliyonse yabwino kwa wodwala. Kaya munthu adya kapena ayi, zilibe kanthu kuti mankhwalawo agwira bwino ntchito. Koma pali malingaliro apadera: simungathe kuwaluma ndi kuwadula, koma muyenera kuwameza lonse ndi madzi ambiri.

Chithandizo chimapangidwa kuti amwe mapiritsi nthawi yayitali, mogwirizana ndi zakudya zomwe zimakhazikitsidwa isanayambe.

Zotsatira zoyipa

Kuphatikiza pazomwe zimapangitsa kuti asagwidwe ndikusokonekera, Tricorr ali ndi zovuta zingapo zomwe sizimachitika kawirikawiri, koma muyenera kudziwa za iwo. Amatha kupweteka mkati mwa m'mimba, kusanza, hepatitis, kapamba, kutupa m'matumbo a mafupa, myasthenia gravis, strin thrombosis, pulmonary embolism, vuto logonana, mutu, ndi ena.

Ngati pali zizindikiro zomwe zingasonyeze hepatitis, tikulimbikitsidwa kuyezetsa magazi ndikuchotsa mankhwalawo ngati matendowo atsimikiziridwa.

Bongo wambiri. Pankhaniyi, chithandizo chamankhwala, ndipo nthawi zina chothandizira, ndikulimbikitsidwa. Tiyenera kukumbukira kuti pakadali pano palibe deta yantchito inayake, ndipo hemodialysis siyikupereka kanthu.

Kuchita ndi mankhwala ena

Popeza Tricor ndi mankhwala ogwiritsira ntchito nthawi yayitali, ndikofunikira kudziwa za kuyanjana kwake ndi mankhwala ena.

Chifukwa chake, kukulitsa mphamvu ya mankhwala omwe amachepetsa magazi, amatha kuwonjezera magazi. Cyclosporine ndi fenofibrate, yotengedwa nthawi yomweyo, imatha kuyambitsa matenda aimpso, koma izi zimatha kusintha. M'magawo onse awiri, adotolo amafunikira kuti asinthe kuchuluka kwa mankhwalawa ndikuwonetsetsa kuwunika kwa magazi pafupipafupi.

Kuphatikizidwa kwa fenofibrate ndi HMG-CoA reductase inhibitors, ma fiber ena kumawonjezera chiopsezo chowononga chachikulu pamafupa a minofu. Kulandila kwawo kophatikizana ndikotheka m'malo ochepa. Chizindikiro kwa iye chikhoza kukhala kuphwanya kwakukulu kwa kuphatikiza mafuta kagayidwe kosakanikirana ndi chiwopsezo chachikulu cha mtima, kenako ndikupereka kuti wodwalayo sanadwalidwe ndi matenda a minofu. Odwala otere amafunikira chisamaliro chowonjezereka, cholinga ndikuwonetsa mwachangu kukula kwa zotsatira zoyipa pamisempha.

Migwirizano ndi magwiritsidwe akusungidwa

Malipenga amasungidwa mu bokosi la makatoni a fakitale kwa zaka zitatu kuyambira tsiku lopangidwa. Kutentha kosungirako - mpaka 25 ° С. Chotupacho chikuyenera kutetezedwa ku dzuwa ndi chinyezi. Kugwiritsa ntchito mapiritsi omwe akhala akusungidwa kwanthawi yayitali m'maselo owonongeka sikuvomerezeka. Monga mankhwala ena, sayenera kupezeka kwa ana.

Pambuyo pake ntchito sikugwiritsidwa ntchito, chifukwa izi zingaphatikizepo kusadalirika kwa thupi.

Imapezeka ku pharmacies ndi mankhwala.