Amafuna kukhala ndi moyo wamphamvu komanso wathanzi? Lembani nkhani yathu ya Wellness Wire yamitundu yonse yazakudya, kukhala wathanzi komanso thanzi.

Pafupifupi zaka 100 zapitazo, mu 1922, asayansi anapeza njira yolimbana ndi matenda a shuga ndi jakisoni wa insulin. Kuchokera nthawi imeneyo, kupita patsogolo kwina kwachipatala ndi ukadaulo kwawoneka komwe kwapangitsa moyo wa anthu ambiri kukhala ndi matenda ashuga. Ndipo pali ambiri: kuzungulira padziko lapansi pakadali pano pali odwala matenda ashuga okwana 371 miliyoni, ndipo chiwerengero chawo chikukula. Tekinoloji zamakono, kumene, zimathandizanso kuthandizira. Nazi zinthu zisanu ndi ziwiri zomwe zimathandiza anthu odwala matenda ashuga tsiku lililonse.

Medtronic adapanga "pancreas woyamba" padziko lapansi

Mu Seputembala, FDA idavomereza chipangizochi, chomwe nthawi zambiri chimatchedwa "kapamba wochita kupanga," kuti chizigwiritsidwa ntchito ponseponse kwa odwala azaka zopitilira 14. Dzina lake ndi MiniMed 670G, ndipo limangoyendetsa shuga wa wodwalayo ndikuvulaza insulin momwe ikufunikira, kotero wodwalayo sayenera kuchita izi payekha. Mwambiri, imalocha m'malo “enieni” kapamba, amene amalamulira kuchuluka kwa shuga m'magazi mwa anthu athanzi. Minus imodzi - muyenera kuwonjezera insulin maola 12 aliwonse, koma ndi yosavuta kuposa kunyamula ma syringes.

Medtronic

Startup Livongo adapanga polojekiti ya glucose, yomwe imalandila zosintha ngati foni yam'manja

"Odwala sasamala zaukadaulo. Amangofuna kukhala ndi moyo wawo, ”anatero Glenn Tulman, mlengi wa Liveongo, pamachitidwe ake. Mavuto a odwala matenda ashuga amadziwika bwino, chifukwa mwana wake wamwamuna amadwala matenda a shuga 1.

Kuwunika kwa glucose komwe Livongo amatha kusintha pulogalamuyi - kutanthauza kuti, anthu safunikira kusintha zida zawo kukhala zamtundu watsopano pamene mapulogalamu akuwunika akupanga.

Livongo

Bigfoot Biomedical imapanganso "kapamba wochita kupanga"

Woyambitsa Bigfoot Biomedical Jeffrey Brewer anali m'modzi mwa anthu oyamba kupereka ndalama ku JDRF, bungwe lofufuza za matenda ashuga, kuti apange chikhodzodzo. Koma pomwe kafukufuku wawo adakana, adaganiza zodzichitira yekha. Anagula kampani ya insulin pump, yogwirizana ndi Dexcom, wopanga ma insulin, ndipo anayamba kupanga makina ogwiritsa ntchito pulogalamu yomwe imagwirira ntchito pa smartphone ndipo "sizikuwoneka ngati mukuthawa kuchipatala." Mayeso oyamba a chipangizocho adayamba mu Julayi, ndipo kampaniyo ikuyembekeza kukhazikitsa chipangizochi pamsika pazaka zingapo zikubwerazi.

Bigfoot

Omwe amapanga Omnipod, pampu yoyamba ya insulin yopanda chopanda, amapanga "ziphuphu zakumaso" zomwezo

Insulet, kampani yomwe idapanga pampu ya insulin ya Omnipod, Seputembala iyi idayambitsa mayesero azachipatala a "kapamba wochita kupanga" ndi Dexcom. Omnipod yokha idayambitsidwanso kumbuyo kwa 2005, ndipo kampaniyo ikukonzekera kuyambitsa ntchito yake yatsopano mu 2018. Mosiyana ndi zida zina, chitukuko cha Insulet chidzaikidwa mwachindunji mthupi ndipo chimakhala ndi mlingo wa insulin masiku atatu, ndipo chiwongolero chidzachitika ndi woyang'anira wopanda zingwe .

Insulet

Dexcom wapanga pulogalamu yowunika ma glucose opanda zingwe yomwe imatumiza deta ku smartphone

Mbali yofunika kwambiri pazomwe tafotokoza apa za Insulet ndi Bigfoot ndi njira yowunikira shuga ya Dexcom. Kupitiliza mopitilira sikuwonetsa mphindi zokha pomwe kuchuluka kwa glucose ndikofunikira kwambiri kapena kocheperako, komanso zimakupatsani mwayi kuti mumvetsetse ngati glucose ikukula kapena ikugwa kwakanthawi. Endocrinologists zimatsimikizira kuti kuwunika pafupipafupi kuchuluka kwa shuga m'magazi kumawongolera kuwongolera kwakadali pano.

Kuphatikiza pa kutenga nawo gawo pakukonza machitidwe ochita kupanga pancreatic, Dexcom ikugwiranso ntchito ndi Google Verify kuti apange kuwongolera kowoneka bwino kwambiri komanso kowoneka bwino kwa glucose.

Dexcom

Timesulin adapanga cholembera chomwe chikuwonetsa kuti anali liti jekeseni womaliza

Kwa anthu onse omwe ali ndi matenda ashuga amtundu 1 komanso gawo limodzi la matenda ashuga a 2, jakisoni wa insulin ndi gawo limodzi lamoyo. Ena amagwiritsa ntchito mapampu a insulini, ena amakonda ma syringe ndi ma ampoules, kapena zolembera zosavuta kwambiri.

A John Sjolund, omwe akhala akudwala matenda ashuga amtundu 1 kwazaka zopitilira 30, apanga cholembera chomwe chimasunga nthawi jekeseni womaliza. Dongosolo lake lotsatira ndikuwonetsetsa kuti izi zikuwonetsedwa mufoniyi.

Timesulin

Google Verify ikupanga mankhwala atsopano

Mu Seputembala, Google Verify idalengeza kukhazikitsidwa kwa kampani yotchedwa Onduo, yomwe ikupanga njira zowonjezera komanso kukhazikitsa chithandizo cha matenda ashuga. Akugwiranso ntchito polojekiti ya mandala a glucose mogwirizana ndi Novartis. Chifukwa cha zidziwitso zonse zomwe angatenge, akonza njira zatsopano zopangira chithandizo ndi kupewa zomwe zingapangitse kuti kulimbana ndi matenda ashuga kukhale kosavuta komanso kotchipa.

Google

Kodi "kapamba wochita kupanga" amayamba ndi chiyani?

Ngakhale "Artificial Pancreas" akumveka ngati chipangizo chimodzi chomwe mumangoyika m'thupi lanu, chowonadi ndi ichi: sitinafikebe.

Ofufuza makumi ambiri adakwanitsa kufikira pomwe amatha kulumikizira zida zosiyanasiyana za shuga pogwiritsa ntchito zingwe zamagetsi komanso ukadaulo wopanda zingwe kuti apange dongosolo lomwe lingafanane ndi zomwe kapamba wamtenda wabwino amatsatira poyang'ana kuchuluka kwa glucose ndikupereka insulini pakufunika.

Chifukwa chake, tsopano omwe amatchedwa "ma pancreas opanga", ndipopompopu ya insulin yolumikizidwa ndi pulogalamu yowonera glucose (CGM), yoyendetsedwa kudzera mwa wolandila wina (nthawi zambiri wogwiritsa ntchito foni yamakono) pogwiritsa ntchito ma algorithms apamwamba kwambiri zinagwira ntchito.

Lingalirolo ndi kusinthitsa kuwunika kwamisempha yamagazi kwambiri momwe angathere, kotero mwiniwake safunikiranso kuwerenga zowerengera za shuga, kenako nkuchita masamu ovuta kuti muwone kuchuluka kwa insulini kapena kuchuluka kwa insulini pakuwerengera kotsika. Makina ena amatha kuzimitsa kuperekera insulini zokha malinga ndi kuchuluka kwa shuga m'mwazi womwe wapezeka ndi CGM. Ndipo machitidwe ena akuyesera kunyamula glucagon kupita kupampu limodzi ndi insulin kuti abweretse shuga yamagazi pakafunika.

Njira izi zidaphunziridwabe, ndipo pakalembedwe kameneka (Epulo 2016), palibe malonda pa AP pamsika pano. Koma maulendo owoneka bwino akupangidwa, ndipo magulu atsopano akuwoneka kuti akugwira ntchito pakupititsa patsogolo kosangalatsa nthawi zonse.

Zogulitsa zomwe zidaphatikizidwa mu makina a AP omwe alipo:

• pampu ya insulini yomwe imapereka insulin kulowa mthupi mosalekeza kudzera "kulowetsedwa" kapena kansalu kakang'ono kamene kamayikidwa pakhungu

• kuwunika kokhazikika kwa glucose (CGM) komwe kumalandira kuwerenga kwa shuga kudzera mu sensor yaying'ono yovala pakhungu lomwe limakhala ndi cannula yosiyana ndi pampu. Pali ma CGM awiri pano pamsika, kuchokera ku Dexcom ndi Medtronic

• chowongolera (nthawi zambiri chimakhala iPhone) chomwe chimakhala ndi chiwonetsero chazithunzi pomwe ogwiritsa ntchito amatha kuwona pulogalamu ya algorithm ya glucose

• , "Ubongo" wamachitidwe omwe amakanikiza manambala kuti adziwe komwe kuchuluka kwa glucose kenako ndikuwuza pampu kuti ichite chiyani

• Nthawi zina glucagon, timadzi timene timatulutsa shuga m'magazi, timagwiritsidwa ntchito ngati mankhwala othana ndi hypoglycemia (shuga m'magazi)

Ndani akupanga makina awa a AP?

Nayi mndandanda wamakampani omwe akutenga nawo gawo pakukonza pulogalamu ya AP, yokonzekera msika, motengera zilembo:

Beta Bionics - Boston-wobadwa ku Yet Bionic Pancreas University ya Boston, Dr. Ed Damiano ndi gulu laposachedwa lapanga kampani yamalonda kuti ibweretse dongosolo lawo pamsika. iLet ili ndi malo amodzi ogwiritsira ntchito kwambiri ndipo imaphatikizapo makatoni omwe amadzaza insulin ndi glucagon kuti athetse kufunikira kwa kutsitsa kwa buku ndi wogwiritsa ntchito.

Bigfoot Biomedical - Yakhazikitsidwa mchaka cha 2014 ndi wamkulu wa JDRF, a Jeffrey Brewer, Bigfoot adalemba aganyu ena odziwika kwambiri a AP ndipo adagulanso IP (Intellectual Property) ndi Milpitas, CA, office office ku Asante Solutions, kampani tsopano yopanda insulin.

CellNovo & Diabeloop ndi kampani yaku Europe yopukuta ndi yofufuza yaku France yopanga ndikuyesa njira zatsopano za AP ku UK ndi France.

Dexcom, patsogolo pa CGM sensor technology kuchokera ku kampaniyi ku San Diego, ili pamtima pa machitidwe ambiri a AP omwe akupangidwa, kuphatikiza machitidwe ena a DIY (opangidwira nyumba) ophatikizidwa ndi nzika za owononga. Kuti zithandizire kupitanso patsogolo, Dexcom adalumikiza AP algorithm mu chogulitsa chake cha G4 mu 2014 ndipo adasaina mapangano oyanjanitsa ndi mapampu a Insulet (OmniPod) ndi J & J Animas insulin.

Dose Safety ndi chiyambi choyambira Seattle chomwe chikukulitsa chowongolera chazogwiritsidwa ntchito mumagulu a AP.

DreaMed Diabetes ndi oyambitsa oyambira ku Israeli omwe adakhazikitsidwa mu 2014 ngati chopangidwa ndi DREAM International Consortium, ndi cholinga chotsatsa ukadaulo wapamba wa pancreatic pa pulogalamu yake ya Glucositter.

Insulet Corp. ndi Mode ACG, Opanga -Boston opanga mapulogalamu opanda insulin OmniPod adalengeza kuphatikiza ndi CGM Dexcom mu 2014, ndipo posachedwapa alowa mu mgwirizano ndi AP pulogalamu yolimba ya Mode AGC (automated Glucose Control LLC) yachitukuko ndikuphatikiza ma algorithm awo apamwamba mu AP.

J & J Animas - wopanga mapampu a insulin adatulutsa mpope wake wophatikiza ndi CGM Dexcom (Animas Vibe) mu 2014. Pakhala pali malingaliro akuti dongosolo lake lomwe lakhala likuyembekezeredwa kwa nthawi yayitali akhoza kulowa mumsika kale kuposa momwe amayembekezera.

Matenda a shuga a Medtronic ndiye mtsogoleri wazamapampu a insulin, ndipo ndi kampani yokha yomwe imapanga mpope ndi chipangizo cha CGM mokondweretsa zomwe zidayambitsa kuphatikiza shuga (530G) mu 2014, chinthu choyamba chovomerezedwa ndi FDA chatsopano kuti yosalala njira yowongolera zida izi. Medtronic idasainanso mgwirizano wapadera mu 2015 wogwiritsa ntchito Glucositter yokumba pancreatic mapulogalamu machitidwe ake amtsogolo.

Mu Seputembala 28, 2016, Medtronic Minimed 670G Hybrid Enclosed Loop System wavomerezedwa ndi FDA ndipo ndiye kachitidwe koyamba kovomerezeka ka CGM-automatic insulin dosing padziko lapansi. Chifukwa chake, iyi ndiye "kanyumba kapangidwe koyamba" pamsika. Kugwiritsa ntchito sensor ya CGM ya m'badwo wachinayi ndi kampani yotchedwa Guardian 3, imangosintha maziko a insulini (kumbuyo) kuti ibweretse wogwiritsa ntchito pafupi ndi 120 mg / dl momwe angathere, kuchepetsa kuchepa kwa shuga komanso kuthamanga kwa magazi ndipo akuyembekezeka kuyamba ku U.S. kumapeto kwa chaka cha 2017. kenako mkatikati mwa 2017, kupezeka kwa mayiko kudzawonekera.

Pancreum ndi poyambira masomphenya opangidwa ndi injinala wakale wa Insulet yemwe amafuna kupanga magawo atatu opanga modular kuti apange dongosolo la AP kukhala losavuta komanso lothandiza kwa odwala.

Tandem Diabetes Care - omwe amapanga pulogalamu yatsopano ya iPhone-ish t: pampu yopyapyala ya insulin ikupanga dongosolo lophatikiza-CGM lomwe limaphatikizapo onse kulosera kwa hypoglycemia algorithm ndi algorithm yolosera hyperglycemia (shuga yayikulu). Amaliza kale kafukufuku wamkati ndipo akugwira ntchito ndi FDA kuti apeze kuvomerezedwa kwa IDE (Kutulutsidwa kuchokera Kufufuzidwa) kuti mupange kafukufuku wina.

TypeZero Technologies ndi poyambira ku Charlottesville, Virginia omwe adzipatulira pa kafukufuku wotseka wotseka ndi chitukuko cha dongosolo la AP ku University of Virginia (UVA). Akugwira ntchito pazakugulitsa zomwe UVA poyambirira inkatchedwa DiAs (yofupikirako kwa othandizira a shuga).

Zopangira zapakhaza Lingo

Nayi chikopa cha mawu ofunikira:

Ma algorithms - ngati simukuzindikira, ma algorithm ndi malangizo a masitepe apakatikati omwe amathetsa vuto lomwe limakhala nthawi ndi nthawi. Mdziko la AP, pali njira zambiri zosiyana ndi izi - zomwe zimachititsadi manyazi, chifukwa kuyimira ma protocol ndi maulangizi othandizira ndizothandiza kwambiri kwa madokotala onse (kuwunika deta) ndi odwala (kuti athe kupeza machitidwe omwe amapereka zosintha zosinthika zigawo).

Chovala chotseka - kutanthauza, makina oyendetsa okha momwe ntchito, njira kapena makina amayendetsedwera ndi mayankho. Mdziko la shuga, njira yotseka yotseka imakhala kapamba wochita kupanga, komwe kutulutsa kwa insulini kumayendetsedwa ndi mayankho ochokera ku algorithm yochokera mu data ya CGM.

Mahoni awiri - Izi zikugwira ntchito kumakina a AP omwe ali ndi insulin komanso glucagon, timadzi tomwe timasiyana ndi shuga.

UI (mawonekedwe ogwiritsa ntchito)- Tekinoloje ya mawu, yomwe imatanthawuza chilichonse chomwe chimapangidwa mu chipangizo chomwe munthu amatha kulumikizana nayo, ndi chiwonetsero chazithunzi, mitundu, mabatani, zidziwitso, zithunzi, mauthenga othandizira, etc. Ofufuzawo adazindikira kuti mawonekedwe osankhidwa bwino amatha kupweteketsa Izi zitha kukakamiza odwala kugwiritsa ntchito pulogalamu ya AP. Chifukwa chake, kuyesayesa kwakukulu pakalipano kukuchitika pakupanga mawonekedwe ogwiritsa ntchito.

Kuyimitsa Low Glucose (LGS) kapena Threshold Suspend - Izi zimathandizira kuti pulogalamu ya AP itseke kudzipereka kwa insulin ngati cholowa chamagetsi chochepa. Izi ndizofunikira popanga AP yomwe imatha kuwongolera kuchuluka kwa shuga.

#WeAreNotWaiting - hashtag yomwe yakhala mkokomo wa phokoso pakati pa olowera patsogolo omwe ali ndi zatsopano pazida zamankhwala, osadikirira madotolo, opanga mankhwala kapena FDA kuti iwapatse patsogolo. Ntchito za mizu ya udzu iyi yakhala ndi gawo lalikulu pofulumizitsa luso, kuphatikiza pa chitukuko cha AP.

#OpenAPS - "Pancreas system" yopangidwa ndi nyumba yopangidwa ndi anthu osokoneza bongo a Dana Lewis ndi Scott Leibrand. Ntchito yawo yodabwitsa idayambitsa kusuntha, popeza odwala ochulukirachulukira anayamba kugwiritsa ntchito ndikubwereza dongosololi. FDA yazindikira OpenAPS ndipo ikuvutikabe ndi momwe angayankhire.

FDA ndi JDRF ikulimbikitsa kupita patsogolo kwa AP

M'malo mwake, akhala akukankhira izi kwa zaka khumi!

Njira yopita ku AP: Kubwerera ku 2006, JDRF idapanga Artificial Pancreas Project Consortium (APPC), ntchito yopanga zaka zambiri, miliyoni miliyoni yolimbikitsa chitukuko cha AP. Izi zinali zabwino kwambiri, mchaka chomwechi, FDA idatchulanso ukadaulo wa AP imodzi mwa njira zake zopangitsanso njira zatsopano zopangira sayansi.

Utsogoleri: Kenako, mu Marichi 2011, JDRF idapempha utsogoleri wa FDA kuti apange malingaliro othandiza kupititsa patsogolo chitukuko. JDRF, pamodzi ndi akatswiri azachipatala, adapanga izi poyambira, zomwe zidatulutsidwa mu Disembala 2011.

Kuyesa kachipatala koyamba: Mu Marichi 2012, FDA idapereka kuyera koyambirira kwamachitidwe azachipatala a AP.

Kuvomerezeka: Mu Seputembara 2016, pomwe FDA idavomereza Medtronic Minimed 670G, "system yotsekedwa yozungulira" yomwe imangodzikongoletsa yokha insulin ndipo ikhoza kulosera zamasewera ena ndi hyperglycemia, mphindi yofunika idadziwika. Chipangizochi chimatseka pang'ono, koma si malo athunthu opezera chilichonse ogwiritsa ntchito. Izi ndizotsatira zopitilira zaka khumi zotsatila, mfundo, kafukufuku ndi chitukuko cha zinthu. Kuvomereza uku akuyembekezeka kukhazikitsa njira kwa njira zina zotsekeka.

Ziyeso zamankhwala za kapamba wochita kupanga

Monga lero, pali masamba mazana angapo mdziko lonse lapansi komanso padziko lonse lapansi omwe amayesa mayeso azachipatala - ambiri aiwo pamwambo wongotuluka, ndiye kuti, omwe amaphunzira nawo samangokhala kuchipatala kapena kuchipatala.

Mayeso awiri mwatsopano kwambiri, omwe adayamba mu Januware 2016, akuyembekezeka kukhazikitsa njira yolandirira FDA ya malonda, kutsimikizira zotetezeka ndi kachitidwe ka AP nthawi yayitali (kuyambira miyezi isanu ndi umodzi mpaka chaka) "m'malo achilengedwe a wodwala."

Palibe zinthu ngati zosasokoneza

Anthu ambiri osadziwika ndi matenda ashuga adzadabwa kudziwa kuti zida zonsezi zikubowola khungu lathu chifukwa akupitilizabe kumva za tekinoloje yosavomerezeka ya shuga.

Ngakhale ndizowona kuti insulin yatsopano yomwe ikulowera inagwera msika chaka chatha (ManreKind's Afrezza), pakadali pano, kuti insulini yokha yopezera chakudya inali yosakwanira kuti igwiritsidwe ntchito mu kachitidwe kapamba kakang'ono. Makina amakono a AP amagwiritsa ntchito pampu yomwe imatulutsa insulini kudzera mu cannula ya "subcutaneous" (pansi pa khungu).

Ndilotinso kwa zaka zambiri kuti apange njira yoyezera shuga popanda kukakamira khungu, koma sitinafikeko. Pakadali pano, kuyesa kuyeza BG kudzera pakhungu, kudzera thukuta komanso ngakhale m'maso mwanu sikunakhaleko wopambana. Koma akatswiri akadali olimbika pantchito akuyesera. Chonde dziwani kuti Google ikupanga ndalama popanga magalasi ochezera. Wambitsani zala zanu (kapena maso anu?) Chifukwa cha izi!

Zovuta zamakono za matenda ashuga

Mu matenda, mankhwala akuluakulu amakhalabe ndi insulini ya mahomoni, omwe amayenera kulowetsedwa m'magazi nthawi zonse ndi syringes kapena mothandizidwa ndi zida zapadera zamagetsi - pampu ya insulin.

Jekeseni wa insulin mu mtundu wa matenda a shuga nthawi zambiri amayenera kuchitidwa kawiri pa tsiku, ndipo nthawi zina 3-4.

Ngakhale njira zopewera za matenda ashuga zomwe zilipo masiku ano ndizothandiza, kuperekera insulin kwa odwala sikokwanira 100% pazosowa zake pakalipano. Ndipo zosowa izi zimasiyanasiyana tsiku ndi tsiku, kutengera zakudya, zolimbitsa thupi, komanso azimayi, komanso gawo la kusintha kwa msambo komwe kumachitika chifukwa cha kusinthasintha kwa chidwi cha insulin.

Dr. Roman Hovorka ndi Dr. Hood Thabit aku University of Cambridge ku England adafotokoza kuti kapamba wochita kupanga ndiye woyenera kwambiri kuwunikira mosalekeza ndikupereka insulin yoyenera. Chipangizochi chimachotsa kusinthasintha kwakukulu m'magulu a shuga, zomwe zikutanthauza kuti zimalepheretsa zovuta zovuta za shuga.

Kafukufuku wambiri wasayansi watsimikizira kugwira ntchito kwa kufalikira kwa maselo, komwe othandizira, maselo omwe amagwira ntchito amasinthidwa kwa odwala omwe ali ndi matenda a shuga a shuga kuti apange insulin. Koma pali zovuta zambiri ndi njirayi, ndipo zotsatira zake ndizochepa kwa zaka zingapo.

Mu magazine a Diabetesologia, Govorka ndi Tabith alemba kuti kapamba wochita kupanga sakhala njira yosavulaza komanso yotetezedwa yothanirana ndi shuga a mtundu I omwe amadalira matenda a shuga. Zimathandizanso odwala jakisoni wa mahomoni ndi kufunika kosinthanso shuga.

Kuyesedwa kwa Njira Yotseka

Pakadali pano, m'maiko osiyanasiyana mdziko lapansi akukumana ndi zosankha zingapo kapamba kapangidwe kake.

Kumayambiriro kwa chaka chino, University of Virginia (USA) idanenanso kuti akugwira ntchito kapamba pogwiritsa ntchito foni yakutali, mayeso awiri azachipatala atsimikizira kale chipangizochi.

Ngakhale pali mapangidwe osiyana, onsewa ndi otengera dongosolo lotsekeka. Ichi ndi njira yowunika yowonera shuga yolumikizidwa ndi pampu ya insulin (poservoir), yoyendetsedwa ndi ma algorithms apadera.

Dr. Govorka ndi anzawo akuti makina otsekeka anachitika bwino kwambiri m'mayesero azachipatala pazinthu zosiyanasiyana. Anathandiza odwala molondola kuwongolera shuga kuchipatala, m'misasa ya odwala matenda ashuga, komanso m'nyumba momwe munalibe kuyang'aniridwa kwachipatala.

Mlandu womaliza unakhudza odwala 24 omwe ali ndi matenda a shuga a mtundu woyamba, omwe kwa milungu 6 amakhala kunyumba ndi kapamba wochita kupanga. Pulogalamu yoyesera idakhala yodalirika komanso yotetezeka kwambiri poyerekeza ndi mapampu a insulini.

Makamaka, machitidwe a hypoglycemic anakula kawiri, ndipo shuga yofunikira kwambiri imafikiridwa 11% pafupipafupi.

Kuyembekezera kusintha kwakukulu

Ngakhale kafukufukuyu akupitilizabe, Dr. Govorka ndi Tabith akuyembekezera lingaliro labwino la FDA koyambirira kwa chaka cha 2017.

Nawonso National Institute for Medical Research (NIHR) UK idalengeza kumaliza kwa kuyesa "lotsekeka malupu" pofika theka lachiwiri la 2018.

"Kuchita kapamba wochita kupanga osati kungoganiza zabwino za oyang'anira kudzafunika, komanso kukhazikitsa malo oyenera azachipatala, komanso maphunziro owonjezera a madokotala ndi ogwira ntchito kuchipatala, "asayansi anachenjeza.

Kutenga mbali kwa ogwiritsa ntchito komanso chiopsezo ndi mavuto akuluakulu

FDA, yomwe udindo wawo wodera nkhawa za chitetezo cha odwala, ndikomveka, umaganizira zoopsa zomwe zimakhudzana ndi dongosolo la automated lomwe limapereka insulin popanda munthu kulowererapo. Kapena popanda kulowererapo kwa anthu. Sizikudziwika kuti wogwiritsa ntchito AP adzayenera "kulengeza" zakudya kapena masewera olimbitsa thupi omwe akubwera. Ndipo makina ambiri amaphatikiza ma alamu olimbikitsa kuwongolera ogwiritsa ntchito komanso kulowerera pakafunika.

FDA idatenganso nthawi yayitali kuti ivomereze gawo loyamba la njira yoyendetsera payekha - ntchito ya "kuyimitsa insulini" mu pulogalamu ya Medtronic, yomwe imalepheretsa kuperekanso insulin kwa maola awiri usiku pamene misempha yotsika magazi ifika ndipo wosagwiritsa ntchito sayankho nkhawa.

Ngakhale malingaliro a FDA anali akuti kuletsa kuperekera mankhwala a insulin ndi chiopsezo kwa wodwala, anthu ambiri omwe amamwa insulin amawawona mosiyana.

kuganiza (kuphatikiza mgodi wathu) ndi motere:

Insulin ndi mankhwala oopsa kwambiri. Odwala amalakwitsa nthawi zonse, chifukwa chake zonsezi zimakhala ndi pulogalamu yoyenera yomwe imatha kupereka malingaliro oyenera. Ngati wina akumana ndi vuto la nocturnal hypoglycemia, pali zoopsa zambiri zomwe zimakhudzana ndi kusayimitsidwa kwa kuperekera insulin kuposa kumulola kuchita kanthu.

Monga njira zamankhwala zonse, pali zoopsa komanso kunyengerera. Koma ife, odwala omwe moyo wawo umadalira insulini, kuti pulogalamu ya AP ingachepetse zoopsa tsiku lililonse zomwe timakumana nazo kwambiri hypoglycemia ndi suboptimal glucose control.

Werengani zonse za izi: Kuphunzira kwapadera pancreatic

Tili mkati 'Zanga anali akupanga AP bola nthawi yayitali. Nayi mndandanda wazomwe talemba kuyambira koyambirira kwa 2014 mpaka pano (Seputembara 2016):

NewsFLASH: FDA ivomereza zoyambirira zapakhomo za Medtronic Minimed 670G (September 29, 2016)

Mayeso Ochepera 670G Ma hybrid Otsekedwa Lolemba (Julayi 2016)

New iLet Bionic Pancreas + Nkhani zina kuchokera kwa abwenzi moyo wonse (Julayi 2016)

Kuyambitsa Bionactics: Kapangidwe Katsopano ka Bizinesi ya iLet Bionic Pancreas (Epulo 2016)

Nthawi yanga ndi iLet Bionic Pancreas "- Mayeso oyamba a anthu! (Marichi 2016)

Ukadaulo wamatenda a shuga wotsekedwa-loop: iLET, Bigfoot, TypeZero, ndi zina zambiri! (Ogasiti 2016)

Zosintha za #WeAreNotWaiting - Slideshow kuchokera ku Msonkhano Watsopano wa Zovuta Zakugawa wa 2015 (Novembara 2015)

Tekinoloji ya TypeZero: Zoyembekeza Zapamwamba Zakugulitsa Zoyendayenda Pazungulira (June 2015)

Kumanani ndi Banja Lalikulu la Bigfoot ndi Maofesi Awo Okhazikika Kunyumba (Marichi 2015)

Ndi mphete iyi, ndimatseka malupu - ndi #OpenAPS (Marichi 2015)

Moyo wapanthawi yopanga tinthu tating'ono (December 2015)

Chosangalatsa cha iLET - A Poyamba a Bionic Pancreas (Novembara 2015)

Ripoti Lachitukuko cha Pancreatic: Makina Otsekeka Otsekeka Tsopano Tsopano Prototype (Ogasiti 2014)

Tom Brobson ndiwotsogolera pancreatic msewu (February 2014)