Glucophage 750: ndemanga

Gawo lalikulu la mankhwalawo ndi chachikulu yogwira mankhwala ndi metformin. Piritsi, ilipo mu mawonekedwe a hydrochloride.

Mankhwalawa amapangidwa ndi opanga mankhwala mwanjira ya piritsi. Mapiritsi amaikidwa m'matumba apadera ndipo amasindikizidwa ndi zojambulazo za aluminiyamu. Piritsi lililonse lili ndi mapiritsi 15 a mankhwala.

Mankhwala, kukhazikitsidwa kwa mankhwala Glucofage kwa nthawi yayitali kumachitika m'makatoni okhala ndi matuza a 2 kapena 4. Phukusi lililonse la mankhwala Glucofage lalitali 750 lili ndi malangizo ogwiritsira ntchito, omwe amafotokoza mwatsatanetsatane magawo onse ogwiritsira ntchito mankhwalawa pochiza matenda a shuga.

The zikuchokera mankhwala ndi zimakhudza thupi la odwala matenda ashuga

Chofunikira chachikulu - metformin, ndi gulu la gulu la Biguanide.

Gulu la Biguanide lili ndi kutchulidwa kwa hypoglycemic.

Kuphatikiza pa metformin hydrochloride, mapiritsi a mankhwalawa ali ndi zinthu zomwe zimagwira ntchito yothandiza monga gawo lalikulu lomwe limagwira ntchito.

Zothandiza pazinthu izi zikuphatikiza izi:

• carmellose sodium
• hypromellose 2910 ndi 2208,
• MCC
• magnesium wakuba.

Mapiritsiwo ali ndi chophatikizira chachikulu 750 mamililita.

Mukamamwa mankhwala a Glucofage Long, chigawocho chimagwira kwathunthu kuchokera ku mawonekedwe a m'mimba m'magazi. Ngati mankhwalawa amatengedwa nthawi yomweyo ndi chakudya, mayamwidwe amachepetsa.

Pambuyo mayamwidwe, bioavailability wa phula pafupifupi 50-60%. Alowa m'matipi amthupi, metformin imagawidwa mwachangu kuzinthu zonse. Pa kayendedwe, mankhwala omwe amapanga kwenikweni samapangidwa ndi mapuloteni omwe ali m'madzi a m'magazi.

Metformin simalimbikitsa kuphatikizira kwa insulin m'maselo a beta a kapamba, chifukwa chake, kuyambitsa kwa mankhwala mthupi sikumapangitsa kuti muzindikire zambiri za hypoglycemic.

Metformin imakhala ndi mphamvu yolimbikitsira maselo a minofu yotengera insulin. Chifukwa cha kuchuluka kwa mankhwala omwe amapanga pama cell, pali kuwonjezeka kwa chidwi cha zolandilira maselo ku insulin, komwe kumakulitsa kupezeka kwa glucose m'magazi.

Kuphatikiza apo, pali kuchepa kwa kaphatikizidwe ka shuga ndi maselo a chiwindi. Kuchepetsa kwa shuga m'magazi kumachitika chifukwa cha kuletsa kwa glycogenolysis ndi gluconeogeneis.

Yogwira popanga imathandizira ntchito ya glycogen synthetase.

Kugwiritsira ntchito Glucofage kutalika mu shuga mellitus kumathandizira kukonza thupi kapena kuchepa kwapang'onopang'ono.

Metformin imayendetsa kagayidwe ka lipid. Kutsegula kwa metabolidi ya lipid kumabweretsa kuchepa kwa zomwe zimakhala m'mafuta a cholesterol, triglycerides ndi LDL m'thupi.

Mapiritsi otsekemera otsekemera amadziwika ndi kuchedwa kuyamwa kwa chinthucho, izi zimapangitsa kuti zotsatira za mankhwalawa zimakhala kwa maola 7 mutatha kumwa mankhwalawo.

Zizindikiro ndi contraindication

Kumwa glucophage ayenera kukhalapo pamaso pa mtundu 2 matenda a shuga odwala omwe ali ndi kunenepa kwambiri chifukwa choti sangathe kugwiritsa ntchito chakudya chamagulu komanso kuchita masewera olimbitsa thupi mwapadera.

Chithandizo cha mankhwalawa chikuchitika pang'onopang'ono ngati mukuchita mankhwalawa kapena mukumagwiritsa ntchito mankhwala ena othandizira ena, kuphatikizapo mankhwala okhala ndi insulin.

Monga mankhwala ena ambiri, Glucofage 850 ya nthawi zonse kapena Glucofage 750 ya nthawi yayitali imakhala ndi zotsutsana.

Milandu yayikulu yomwe sioyenera kumwa ndi:

1. Kukhalapo kwa hypersensitivity kwa gawo lalikulu la mankhwalawo kapena magawo ena a mankhwalawa.
2. Kupezeka kwa zizindikiro za ketoacidosis, precoma kapena chikomokere m'thupi.
3. Kusokonezeka mu ntchito ya impso ndi chiwindi, zomwe zimayambitsa kuwonongeka kwa magwiridwe antchito.
4. Matenda ena ali pamavuto kapena pachimake.
5. Kupeza odwala omwe akuvulala kwambiri komanso nthawi ya opareshoni.
6. Wodwala ali ndi mtundu wosamwa wa kuledzera komanso kuledzera.
7. Kuzindikiritsa Zizindikiro za lactic acidosis.
8. Mukamagwiritsa ntchito chakudya chama hypocaloric kapena mukamachititsa maphunziro pogwiritsa ntchito mankhwala okhala ndi ayodini.
9. Zaka za munthu wodwala matenda ashuga ndizosakwana zaka 18.

Sindikulimbikitsidwa kugwiritsa ntchito mankhwalawa pambuyo pakubereka komanso pakubala mwana.

Kusamala makamaka kuyenera kuthandizidwa popereka mankhwala othandizira odwala okalamba omwe akuchita ntchito yayikulu, izi zimachitika chifukwa cha kutukuka kwa chizindikiritso cha thupi m'thupi.

Kuphatikiza apo, kusamala ndikofunikira pakumwa mankhwala othandizira amayi omwe akuyamwitsa.

Zotsatira zoyipa ndi bongo

Popereka chithandizo chamankhwala, mavuto amabwera mthupi la wodwalayo.

Zotsatira zoyipa zomwe zimadza chifukwa chogwiritsa ntchito mankhwalawa ndi lactic acidosis, kuchepa kwa magazi m'thupi ndi kuchepa kwa mayamwidwe a vitamini B12.

Kuphatikiza apo, maonekedwe osokoneza ma kayendedwe amanjenje samatsutsidwa. Zisokonezo izi zimawonetsedwa ndi kusintha kwa kukoma.

Kuchokera kuntchito ya m'mimba, zotsatirazi zoyipa zingachitike:

• nseru
• kusanza
• kupweteka m'mimba,
• kutsegula m'mimba
• kusowa kwa chakudya.

Nthawi zambiri, zotsatira zoyipa kuchokera kuntchito ya m'mimba zimawonekera nthawi yoyamba ya mankhwala ndipo pamapeto pake zimatha pakapita nthawi.

Kuti muchepetse mavuto obwera chifukwa cha m'mimba, timalimbikitsidwa kumwa mankhwalawo ndi chakudya kapena tikangomaliza kumwa.

Nthawi zina, pamakhala kusintha pakati pa chiwindi ndi maonekedwe a khungu lawo.

Kulandiridwa kwa Metformin mu Mlingo osapitirira 85 g sikubvulaza anthu ndipo sikumupangitsa kukula kwa zizindikiro za hypoglycemia mthupi, pomwe wodwalayo amakhalabe akuonetsa zizindikiro za lactocytosis.

Panthawi ya zizindikiro zoyambirira za lactocytosis, muyenera kusiya kumwa mankhwalawo ndikupempha thandizo kuchipatala kuchipatala kuti mumvetse bwino za matendawo ndikuzindikira kuchuluka kwa lactate m'thupi la wodwalayo. Ngati ndi kotheka, kuchipatala, hemodialysis ndi dalili zozizwitsa zimachitika.

Kuti muchepetse kuthana ndi mavuto, nthawi zambiri amalimbikitsa kuti mapiritsi a Xenical atenge nthawi yomweyo ndi Glucofage Long. Mankhwalawa amagwira ntchito molumikizana ndi Metformin.

Musanayambe kumwa Glucofage yayitali muyezo wa 750 mg kapena mawonekedwe ake, muyenera kuphunzira momwe mankhwalawo amafotokozera malinga ndi malangizo omwe angagwiritsidwe ntchito.

Malangizo ogwiritsira ntchito mankhwalawa

Malangizo ogwiritsira ntchito mankhwalawa amawongolera kuchuluka kwa kuchuluka kwa mankhwalawa. Koma musanagwiritse ntchito mankhwalawa, muyenera kufunsa dokotala wanu za mankhwalawo.

Malinga ndi malangizo, amamwa mapiritsi mkati momwemo, osafuna kutafuna. Kumwa mankhwalawa kuyenera kutsagana ndi kutsuka piritsi ndi madzi ochepa.

Nthawi yabwino kumwa mankhwalawa ndikugwiritsa ntchito nthawi yamadzulo.

Malinga ndi malangizo, kusankha kwa mankhwalawa kumachitika ndi dokotala yemwe amaganizira zotsatira za mayeso ndi machitidwe a thupi. Posankha mlingo woti amwe mankhwalawo, dokotala yemwe amathandizira mankhwalawa amaganizira zomwe zikuwonetsa mu chakudya chamagazi m'magazi a wodwalayo.

Glucophage kutalika kwa 750 mg ndi mankhwala onse omwe amagwiritsidwa ntchito popanga mankhwala a mono. Mukamagwiritsa ntchito mankhwalawa, Mlingo wokhazikitsidwa ndi dokotala wopezekapo uyenera kuyang'aniridwa ndipo magawo a shuga omwe amapezeka m'madzi a m'magazi amayenera kuwunikidwa nthawi zonse.

Nthawi zambiri, mankhwalawa amayamba ndi mlingo wa 500 mg, kawirikawiri, mankhwalawa amayamba ndi mlingo wa 850 mg.

Mankhwala amatengedwa katatu patsiku chakudya. Mlingo utha kuwonjezeredwa ngati pakufunika.

Mlingo wa mankhwala womwe umagwiritsidwa ntchito kukhazikitsa khola lamthupi ndi 1500-2000 mg patsiku.

Zikakhala kuti zakonzedwa kuti zisamutse wodwala kuti atenge Glucofage, ndiye kuti othandizira ena a hypoglycemic ayenera kusiyidwa.

Kugwirizana kwa Glucophage Long ndi mankhwala ena

Glucophage Long ikhoza kugwiritsidwa ntchito ngati gawo la mankhwala othandizira kuphatikiza ndi mankhwala okhala ndi insulin. Mukamagwiritsa ntchito mankhwalawa limodzi ndi jakisoni wa insulin, mulingo wotsatira uyenera kusankhidwa molingana ndi kuchuluka kwa shuga ndi kusinthasintha kwake.

Sitikulimbikitsidwa kugwiritsa ntchito mankhwalawa pochita kafukufuku wamthupi pogwiritsa ntchito mankhwala osokoneza bongo omwe ali ndi ayodini. Maphunziro amenewa asanachitike, oyang'anira Glucofage ayenera kuyimitsidwa maola 48 asanachitike ndikuyambiranso kutenga masiku awiri atatha mayeso.

Pochiza wodwala Glucophagem Long pomwe amamwa mankhwala osakhudzana ndi hypoglycemic zotsatira, ndikofunikira kuyeza kuchuluka kwa shuga m'magazi am'magazi.

Mankhwalawa ndi:

1. Mankhwala a Hormonal.
2. Tetracosactide.
3. Beta -2-adrenergic agonists.
4. Danazole
5. Chlorpromazine.
6. Zodzikongoletsera.

Kumwa mankhwalawa kumafunikira kuwunikira kosalekeza momwe chizindikiro cha shuga m'thupi chimasinthira, ndipo ngati chizindikirocho chikugwera pansi pa mulingo wovomerezeka, mlingo wa Glucofage uyenera kusinthidwa.

Kuphatikiza apo, kuchuluka kwa ma diuretics osakanikirana ndi Glucofage kumatha kupangitsa kukula kwa lactic acidosis mthupi.

Mukamagwiritsa ntchito mankhwala monga mankhwala a sulfonylurea, acarbose, insulin, salicylates, zimachitika ndi kukula kwa zizindikiro za hypoglycemia m'thupi.

Mukagwiritsidwa ntchito pochiza ndi mankhwala monga Amiloride, Digoxin, Morphine, Procainamide, Quinidine, Quinine, Ranitidine ndi ena ena, pali mpikisano pakati pa metformin ndi mankhwalawa pamayendedwe a tubular, zomwe zimapangitsa kukulira kwa kuchuluka kwa Metformin.

Mtengo wa mankhwalawa, mawonekedwe ake ndi ndemanga zake za mankhwalawa

Kugulitsa mankhwalawa kumachitika m'mafakitoreti okha malinga ndi mankhwala omwe adokotala amapita.

Kuti musunge mankhwalawa, muyenera kugwiritsa ntchito malo amdima komanso ozizira, omwe sangathe kuwapeza kwa ana. Moyo wa alumali ndi zaka zitatu.

Ikatha nthawi yosunga mankhwalawo, nkoletsedwa kugwiritsa ntchito mankhwalawa. Ikatha nthawi yosungirako, mankhwalawa amapezeka ndikuchotsa ntchito.

Mankhwalawa ali ndi mitundu yonse ya fanizo. Mankhwala a Analog ali ofanana pakapangidwe kachitidwe ka thupi.

Mankhwala otsatirawa ndi fanizo la mankhwalawa:

• Bagomet,
• Glycon
• Glyformin
• Glyminfor,
• Langerine
• Metospanin
• Methadiene
• Metformin
• Siafor ndi ena.

Mtengo wa Glucofage Long 750 makamaka zimatengera kuchuluka kwa ma CD ndi dera la Russian Federation komwe mankhwalawo amagulitsidwa.

Mtengo wa phukusi lomwe limakhala ndi mapiritsi 30 a mankhwala m'matumba awiri amasiyana malinga ndi dera ladziko lonse kuyambira 260 mpaka 320 rubles.

Mtengo wa phukusi, womwe uli ndi mapiritsi 60 m'matumba anayi, umasiyana malinga ndi dera la Russian Federation, momwe limagulitsidwa pamtunda kuchokera 380 mpaka 590 rubles.

Nthawi zambiri, odwala amasiya ndemanga za Glucofage yayitali 750 mg. Izi ndichifukwa choti mankhwalawa ndiwothandiza kwambiri panthawi ya matenda a shuga 2. Nthawi zambiri, ambiri achire kwambiri zotsatira, kuwunika ndi kuwunika kwa odwala, zimatheka ndi kugwiritsa ntchito mankhwalawo pakatikati pa matendawa. Nthawi zambiri mumatha kuwunika kuti kumwa mankhwala kumatha kuchepetsa thupi kwa odwala onenepa kwambiri omwe ali ndi matenda a shuga a 2.

Ngati mukufuna kugwiritsa ntchito Glucophage kutalika kwa matenda a shuga, ndiye musanagwiritse ntchito mankhwalawa, muyenera kufunsa dokotala ndikuwunika thupi. Kutengera zotsatira za mayeserowa, dotolo wokhazikika azindikira kuti ndibwino kugwiritsa ntchito mankhwalawa kwa nthawi yayitali.

Katswiri wa kanema mu nkhaniyi adzafotokoza za mfundo za Glucofage.

Mitengo ya Glucofage 750

Ndili ndi matenda ashuga a 2. Ndi matendawa, ndikofunikira kwambiri kuti shuga asakwere kuposa mtengo winawake, koma ndibwino kuti muzikhala ndi thanzi labwino. Glyukofazh Long 750 imandithandiza kuthana ndi izi .. Choyamba, adotolo andiyambitsa Glyukofazh 500 mg aliyense. Komabe, mankhwalawa ali ndi zovuta zambiri ndipo ndidamva kuwawa kwambiri. Adadandaula dotolo, nati zimandivuta kumwa. Ndipo adotolo adandipangira kuti ndiziwonjezera Glucofage Long 750. Mankhwalawa amakhala motalika, muyenera kumwa kamodzi patsiku. Ndipo pali zovuta zoyipa zingapo kuchokera pamenepo. Tsopano ndimangomwa, shuga amasungidwa pafupipafupi. Njira yabwino yothetsera.

Amayi anga ali ndi matenda ashuga. Tsoka ilo, ayenera kugwiritsira ntchito insulin, ndipo patapita nthawi Glucofage Long 750 idalembedwa .. Zowonadi ndi zoti mayi anga adayamba kuchira, mkhalidwe wake umakulirakulira, ndipo mankhwalawa amathandizira kutsitsa shuga wamagazi ndikupanga metabolism. Amayi anayamba kumwa mankhwalawo malinga ndi chiwembu chomwe adokotala adamuuza.Pakapita kanthawi, mkhalidwe unayamba kuyenda bwino, kulemera kunachepa pang'ono, kusanthula kunakhala bwino. Amayi amasangalala ndi mankhwalawa, adayamba kuwunika momwe amadyera kuti zotsatira zoyipa zisamachitike. Ndipo ndili chete kuti ali bwino.

Anandipeza ndi matenda a shuga kwa nthawi yayitali. Choyamba, Glucofage 500 idatumizidwa kuti ikhale yofanana ndi shuga, ndiye imasamutsidwa kupita ku Glucofage Long 750. Mankhwala achiwiri amagwira bwino ntchito, ndikosavuta kumwa kamodzi patsiku. Kuchita kwa mankhwalawa ndikokwanira kwa tsiku limodzi, ndipo zotsatirapo zake zimawonekera pang'ono. Sindinapeze vuto lililonse ndikumatenga Glucofage Long 750. Kuwunika komwe kunawonetsa kunawonetsa kuti shuga yanga inali yofunikira pazaka zanga. Ndimapitilizabe kumwa mankhwalawo, monga adokotala adalangiza.

Ndinapita kwa adotolo ndimakamwa onenepa kwambiri komanso owuma, kuti andikayezetsa. Zotsatira zake, matendawa ndi amtundu wa 2 shuga. Glucofage Long 750 idalembedwa, mphamvu ya mankhwalawa ndi yayitali kuposa ya wamba Glucofage. Pakapita kanthawi, ndinazindikira kuti chikhumbochi chikukula kwambiri, ndikufuna maswiti ochepera (ili ndi vuto lalikulu kwa odwala matenda ashuga). Kuphatikizanso ndi phwando kunali kuchepa kwa thupi, ndinataya ma kilogalamu atatu. Ndikosavuta kumwa mankhwala, muyenera kumwa madzi ambiri. Kuyesedwa kwatsopano kukuwonetsa kuti shuga idayamba kuchepa, chifukwa chake ndikupitiliza chithandizo ndi mankhwalawa.

Glucophage Long 750 adandiuza kwa dokotala. Ndine wodwala matenda ashuga; shuga ndiwopitilira muyeso. Ndinaona kuti ndikatenga Glucofage, zimandivuta. Mankhwalawa amachepetsa shuga m'magazi, pomwe vutolo limayenda bwino. Mankhwala omwe ali ndi prefix "Long" amakhala ndi mphamvu yayitali, poyerekeza ndi mankhwala omwe amapezeka, kotero ndimayenera kumwa kamodzi patsiku. M'masiku oyambirirawo, ndimamva kuti sindimakhala bwino, kenako zonse zimayenda bwino ndipo zinthu zinayamba bwino. Dotoloyo akuti mwina ndiyenera kumwa mankhwalawo moyo wanga wonse.

Saw Glyukofazh 500, patapita kanthawi anaika Glyukofazh Long 750, chifukwa kuyambira koyamba zinali zoipa kwambiri. Komabe, ndimamwa yachiwiri ndikuvuta. Ngakhale kuti muyenera kuzipatula pang'ono, zovuta zake zilipo. Nthawi zambiri kuvulala mseru komanso chizungulire, m'mimba limapweteka, kutsegula m'mimba nthawi zambiri kumachitika. Ndili ndi shuga wambiri, ndimadwala matenda ashuga, koma sindidziwa kumwa mankhwalawa. Mkhalidwe wowopsa kwambiri. Ndifunsa adotolo kuti asankhe kena kena kuti achetetse shuga.

Ndakhala ndi matenda ashuga kwa nthawi yayitali, ndalembetsedwa ndi endocrinologist. Nditha kupeza mankhwala onse kwaulere, koma zomwe amapereka zimawononga thupi. Adotolo adalimbikitsa kumwa Glucofage Long 750 kuti muchepetse shuga, koma muyenera kugula nokha. Ndibwino kwa ine kuposa zovuta za mankhwala ena. Ponena za Glucofage, ndimakonda mankhwalawo. Muyenera kumwa kamodzi patsiku chifukwa cha nthawi yayitali, sizinabweretse mavuto. Pazaka zambiri, nditatha miyezi yambiri nditamwa, ndidamva bwino, ndidazindikira kuti ndidataya ngakhale kulemera pang'ono. Ndipitiliza kumwa mankhwalawa kuti pasakhale mavuto ndi shuga wamagazi.

Ndinkamwa mankhwala Glucofage katatu patsiku - ndili ndi matenda ashuga 2. Koma mankhwalawa amayambitsa nseru komanso kusasangalala m'mimba. Ndidapita kwa dotolo, adandiuza kuti alowe m'malo - Glucofage Long 750. Mankhwalawa ndiwotalikilapo, kotero ndikokwanira kumwa piritsi limodzi patsiku. Dokotalayo adalongosola kuti mankhwalawa ali ndi zovuta zochepa kuposa mapiritsi a nthawi zonse. Ndipo zowonadi, ndi Glucophage iyi inali yosavuta, ndimamwa mapiritsi usiku, zotsatira zimatha tsiku limodzi. Izi ndizothandiza kwambiri, chifukwa simukuyenera kuyang'anira nthawi yonse ndikuyenda nanu mapiritsi. Mlingo wa shuga mukamamwa Glucofage Long 750 uli pafupi kwambiri, kotero ndikupitiliza mankhwala ndi mankhwalawa.

Posachedwa ndidapezeka ndi matenda a shuga 2. Glyukofazh Wolemba Long 750. Imwani piritsi limodzi, kumwa madzi oyera ambiri. Sindinazindikire zovuta zilizonse kuchokera ku mankhwalawa. Glucophage imathandizira kuchepetsa shuga, yomwe imakhala ndi phindu m'thupi la munthu. Mphamvu ya mankhwalawa imayamba msanga, imadziwika. Nthawi yoyesedwa yowonjezereka, zidatsimikiza kuti mulingo wanga wa shuga ndi wabwinobwino zandalama zanga. Bhonasi yotheka inali yolemetsa yomwe ingatheke - odwala matenda ashuga nthawi zambiri amadwala mapaundi ochulukirapo. Dotoloyo adati ndikufunika kumwa mankhwalawo kwa nthawi yayitali, motero ndikupitiliza kuthandizidwa.

Ndili ndi matenda ashuga a 2, ndamwa Glucophage zaka zingapo. Posachedwa, adotolo andipempha kuti ndisinthane ndi Glucofage Long 750, ndikufotokozera kuti amwe mapiritsi ochepa. Kuphatikiza apo, adati zotsatira zoyipa mukamamwa mapiritsiwa zimawonekeranso zochepa. Ndinaganiza zoyesera. Inde, ndikofunikira kwambiri kumwa piritsi limodzi, m'malo awiri kapena atatu. Zotsatira zoyipa sizindikiranso. Chinthu chimodzi cholakwika - nthawi zina mapiritsi awa ndi osatheka kugula, samapezeka mufesi. Chifukwa chake, tiyenera kubwerera ku Glucophage yosavuta.