Supombital ndi Cardiomagnyl: zili bwino?

Mankhwalawa amapangidwa ngati mapiritsi okhala ndi filimu: biconvex, ozungulira, wokutidwa ndi filimu komanso pakati pamtanda wa pafupifupi oyera kapena oyera 30 kapena 100 ma PC. mumtsuko wagalasi yakuda (amber), yosindikizidwa ndi kansalu yoyera yopangidwa ndi polyethylene yokhala ndi kapisozi wochotseka wokhala ndi khungu la silika ndi mphete yolamulira kutsegulira koyamba, mu bokosi la makatoni a 1 mtsuko ndi malangizo ogwiritsira ntchito mphamvu.

Piritsi limodzi lili:

• yogwira zinthu: acetylsalicylic acid - 75 mg, magnesium hydroxide - 15.2 mg,
• zina zowonjezera: wowuma wa mbatata, cellcrystalline cellulose, wowuma chimanga, magnesium stearate,
• zokutira filimu: macrogol (polyglycol 4000), hypromellose (hydroxypropyl methylcellulose 15 cPs), talc.

Mankhwala

Supombital ndi kuphatikiza kosakanizira kwa kuphatikizana kwa kupatsidwa zinthu za m'mwazi. Mankhwala chifukwa cha kukakamiza kwa thromboxane A kapangidwe ka maselo₂ amachepetsa kusakanikirana, kuphatikiza mapulateleti, ndi kapangidwe ka magazi. Pambuyo pa limodzi mlingo, mphamvu ya antiplatelet ya mankhwalawa imawonedwa masiku 7 (mwa amuna, zotsatira zake zimatchulidwa kuposa azimayi).

Poyerekeza ndi kusakhazikika kwa angina pectoris, acetylsalicylic acid kumachepetsa kufa ndi chiopsezo cha myocardial infarction, kumawonetseranso kuyendetsa bwino pakuletsa kwapafupa kwamatenda amtima, makamaka myocardial infarction mwa amuna pambuyo pa zaka 40, ndipo akuwonetsa zotsatira zabwino zakuthana ndi kulowetsedwa kwa myocardial. Ichi chogwira ntchito m'chiwindi chimalepheretsa kupangika kwa prothrombin, kumalimbikitsa kuchuluka kwa prothrombin, kuwonjezeka kwa ntchito ya fibrinolytic ya plasma ya magazi ndi kuchepa kwa magawo a zinthu zomwe zimadalira Vitamin K - II, VII, IX ndi X. Pazinthu zopangira opaleshoni, gawo lomwe limagwira limapangitsa ngozi ya hemorrhagic, motsutsana ndi maziko ophatikizana ndi anticoagulants kumawonjezera mwayi wokhetsa magazi.

Ikagwiritsidwa ntchito muyezo waukulu, acetylsalicylic acid imawonetseranso odana ndi kutupa, ma analgesic ndi antipyretic zotsatira, imayendetsa uric acid excretion (kusokoneza njira ya kubwezeretsanso kwa a rebu tubules). Mu mucosa wam'mimba, kutsekeka kwa cycloo oxygenase-1 (COX-1) kumayambitsa kulepheretsa kwa ma gastroprotective prostaglandins, omwe angayambitse zilonda zam'mimba komanso kuwonjezeka kwa magazi.

Hydroxide yomwe ikuphatikizidwa pakuphatikizidwa kwa magnesium thrombital imateteza kuteteza mucosa wam'mimba (GIT) ku zotsatira zoyipa za acetylsalicylic acid.

Pharmacokinetics

Acetylsalicylic acid imatsala pang'ono kulowa m'mimba. Hafu ya moyo (T_½) yogwira ntchito imakhala pafupifupi mphindi 15, chifukwa pansi pa michere imachulukitsa hydrolyzes mu salicylic acid m'madzi am'magazi, chiwindi ndi matumbo. Salicylic acid T_½ pafupifupi maola atatu, koma amatha kuchuluka kwambiri ndi nthawi yomweyo kugwiritsa ntchito milingo yoposa 3 g ya acetylsalicylic acid chifukwa cha kuchuluka kwa ma enzyme. The bioavailability wa acetylsalicylic acid ndi 70%, koma kufunika kwake kungasinthe kwambiri, chifukwa chakuti chinthu chomwe chimapangidwira chimapangidwanso ndimayikidwe a hydrolysis (chiwindi, m'mimba) ndi gawo la michere mu salicylic acid, bioavailability yomwe ndi 80-100%.

Mlingo wa magnesium hydroxide yomwe imagwiritsidwa ntchito sizikhudza bioavailability wa acetylsalicylic acid.

Zizindikiro zogwiritsidwa ntchito

• kupewa kwakukulu kwa zotupa zam'mtima, kuphatikizapo thrombosis ndi mtima wosakhazikika, ndi zovuta zomwe zilipo (mwachitsanzo, matenda oopsa, hyperlipidemia, matenda osokoneza bongo, kusuta, kunenepa kwambiri, ukalamba),
• kupewa magazi chotupa thrombosis ndi myocardial infaration,
• kupewa thromboembolism pambuyo opaleshoni kuchitira pa ziwiya, monga coronary artery bypass grafting, percutaneous translate coronary angioplasty,
• angina pectoris.

Contraindication

• magazi am'mimba, zotupa ndi zilonda zam'mimba zam'mimba thirakiti,
• matenda am'mimba,
• Kulephera kwamtima kwa mtima kwa III - kalasi yogwira ntchito malinga ndi gulu la NYHA (New York Association of Cardiology),
• kuphatikizika kapena kuphatikizika kwathunthu kwa polyposis ya rhinosinusitis ndi mphumu ya bronchial komanso kuvomerezeka kwa acetylsalicylic acid kapena mankhwala ena onse osapweteka a antiidal (NSAIDs), kuphatikizapo cycloo oxygenase-2 inhibitors (COX-2), kuphatikizapo mbiri
• mphumu ya bronchial chifukwa cha kudya kwa ma salicylates ndi NSAID ena,
• Matenda a kukhetsa magazi (hemorrhagic diathesis, thrombocytopenia, kuchepa kwa Vitamini K),
• kulephera kwambiri kwaimpso ndi creatinine chilolezo (CC) pansi pa 30 ml / min,
• Kulephera kwamphamvu kwa chiwindi (Maphunziro a ana-Pugh B ndi C),
• shuga-6-phosphate dehydrogenase akusowa,
• Ine ndi III timayesa kutenga pakati komanso nthawi yoyamwitsa,
• kugwiritsa ntchito methotrexate pa mlingo wa 15 mg pa sabata kapena kupitilira,
• wazaka 18
• Hypersensitivity ku zilizonse za mankhwala ndi NSAIDs ena.

Wothandizirana (kumwa mapiritsi obwezera mosamala mosamala):

• mbiri yakutuluka magazi m'mimba kapena kukokoloka ndi zilonda zam'mimba zam'mimba,
• minofu yaimpso (CC pamwamba 30 ml / min),
• Kulephera kwa chiwindi (Gulu Lopanda Ana),
• matenda ashuga
• aakulu kupuma matenda, bronchial mphumu, mphuno polyposis, hay chifuwa, matupi awo sagwirizana, mankhwala chifuwa, kuphatikizapo mawonekedwe a khungu zimachitika, kuyabwa, urticaria (popeza acetylsalicylic acid kungayambitse bronchospasm, komanso kupweteka kwa bronchial mphumu kapena chitukuko cha zochitika zina za hypersensitivity),
• gout, hyperuricemia, chifukwa acetylsalicylic acid, omwe amatengedwa mu yaying'ono Mlingo, amachepetsa kuchotsa kwa uric acid,
• II trimester wa pakati,
• kuchitapo kanthu koperekera opaleshoni (kuphatikiza yaying'ono ngati kutulutsa mano), chifukwa kupatsirana kungayambitse magazi kwa masiku angapo mutatha kumwa,
• ukalamba
• kuphatikiza pamodzi ndi mankhwalawa: NSAIDs ndi mankhwala ambiri okhathamiritsa amtundu wa asidi, digoxin, valproic acid, anticoagulants, antiplatelet / thrombolytic othandizira, methotrexate pa mlingo womwe uli pansi pa 15 mg pa sabata, insulin ndi pakamwa othandizira a hypoglycemic (sulfonylurea-derivatives. mankhwala a serotonin, ethanol (kuphatikizapo zakumwa za ethanol), ibuprofen, systemic glucocorticosteroids (GCS), kukonzekera kwa lifiyamu, carbonic anhydrase inhibitors, sulfonamides, mankhwala RP G analgesics.

Thrombital, malangizo ntchito: njira ndi mlingo

Mapiritsi a thrombital amatengedwa pakamwa, kutsukidwa ndi madzi, 1 nthawi patsiku. Ngati mukuvutikira kumeza piritsi lonse, mutha kutafuna kapena kuwaphwanya kukhala ufa.

Mlingo woyenera wophatikizidwa:

• matenda amtima, kuphatikiza thrombosis ndi matenda a mtima pachimake ndi zinthu zomwe zingayambitse kupewa: tsiku loyamba - mapiritsi 2, ndiye piritsi limodzi patsiku,
• thromboembolism pambuyo opaleshoni ya mtima, mobwerezabwereza myocardial kulowetsedwa ndi magazi chotupa thrombosis pofuna kupewa: tsiku lililonse mapiritsi 1-2,
• osakhazikika angina: tsiku lililonse mapiritsi a 1-2, kuyamwa mwachangu, piritsi loyamba la mankhwalawa tikulimbikitsidwa kutafuna.

Thrombital anafuna kuti ntchito kwa nthawi yayitali, mlingo wa mankhwalawa komanso kutalika kwa mankhwala amatsimikiziridwa ndi adokotala.

Tengani mankhwalawa akufunika kokha pamankhwala omwe ali pamwambapa malinga ndi zomwe akuwonetsa.

Zotsatira zoyipa

• Mchitidwe wamanjenje: Nthawi zambiri - kusowa tulo, kupweteka mutu, pafupipafupi - kugona, chizungulire, kawirikawiri - tinnitus, intracerebral hemorrhage, osadziwika pafupipafupi - kulephera kumva (kungakhale chizindikiro cha kuchuluka kwa mankhwalawa),
• hematopoietic dongosolo: pafupipafupi - magazi ochulukirapo (magazi amkamwa, mphuno, ma hematomas, magazi ochokera ku genitourinary thirakiti), kawirikawiri - kuchepera magazi - thrombocytopenia, hypoprothrombinemia, aplasic anemia, neutropenia, eosinophilia, agranulocytosis, ndi pafupipafupi - Pakhala pali malipoti amilandu yayikulu yotaya magazi (mwachitsanzo, kutulutsa magazi m'mimba ndi matenda otupa m'mimba, makamaka kwa odwala omwe ali ndi matenda oopsa omwe sanachite nawo kuthamanga kwa magazi ndipo / kapena kulandira chithandizo chothandizirana ndi mankhwala opha matenda a anticoagulant), nthawi zina kukhala ndi vuto lowononga moyo, kutaya magazi kungayambitse kuchepa kwamatenda kapena kusowa kwazitsulo / kuchepa kwa magazi m'magazi (mwachitsanzo, chifukwa chakuwukha magazi) ndi ziwonetsero za kuchipatala komanso zantchito yothandizira , asthenia, hypoperfusion), mwa odwala omwe ali ndi vuto lalikulu la kuchepa kwa shuga-6-phosphate dehydrogenase, milandu ya hemolysis ndi hemolytic anemia,
• kupuma dongosolo: Nthawi zambiri - bronchospasm,
• kwamikodzo dongosolo: ndi pafupipafupi mawonekedwe - mkhutu aimpso ntchito ndi kupweteka kwambiri aimpso,
• zam'mimba dongosolo: pafupipafupi - kutentha pa chifuwa, nthawi zambiri - kusanza, nseru, zilonda zam'mimba, zilonda zam'mimba, kuphatikizapo zilonda zam'mimba, magazi osowa - kuchuluka kwa michere ya chiwindi, osowa kwambiri - stomatitis, zotupa zotupa za chapamimba m'mimba, ma strictures, esophagitis, colitis, matumbo osakwiya, osadziwika pafupipafupi - kuchepa kwa chakudya, kutsegula m'mimba,
• thupi lawo siligwirizana: pafupipafupi - urticaria, edema ya Quincke, pafupipafupi - anaphylactic zimachitika, kuphatikizapo angioedema, osadziwika pafupipafupi - zotupa pakhungu, kuyabwa, kutupa kwammphuno, matenda a mtima, matenda a mtima .

Pakakhala mawonekedwe / ochulukitsa pazomwe tafotokozazi pamwambapa kapena pakachitika zolakwira zina, ndikofunikira kukaonana ndi katswiri.

Bongo

Mankhwala osokoneza bongo a thrombital amatha kudziwika pambuyo pa limodzi lokha la mlingo waukulu, komanso ndi chithandizo cha nthawi yayitali. Ndi muyezo umodzi wa acetylsalicylic acid pa mlingo womwe uli pansi pa 150 mg / kg, poyizoni wa pachimake amadziwika kuti ndi wofatsa, pa mlingo wa 150-300 mg / kg - odziletsa, ndipo akamagwiritsidwa ntchito pamlingo waukulu - woopsa.

Zizindikiro za mankhwala osokoneza bongo kuchokera pakakhala pang'onopang'ono mpaka pang'ono: monga kuwonongeka kwamaso, kumva makutu, kupweteka kwa mutu, kutsekemera, chizungulire, kutuluka thukuta, kusanza, nseru, Hyperventilation, tachypnea, chisokonezo, kupuma. Ndi kukula kwa zizindikirozi, amalengeza kuyambitsa kusanza ndikukakamiza zamchere zamkati, kugwiritsidwa ntchito mobwerezabwereza kaboni, ndipo amayesedwa kuti abwezeretse kuchuluka kwa ma electrolyte ndi acid-base state.

Zizindikiro zakuchuluka kwa Thrombital kuyambira pang'ono mpaka kukula kwambiri zingaphatikizepo: kutentha kwambiri kwa thupi (hyperpyrexia), kupuma kwamatumbo ndi compensatory metabolic acidosis, hyperventilation, kupuma, osagwirizana ndi cardiogenic pulmonary edema, asphyxia, kuchepa kwa magazi, kusokonezeka kwa mtima. , magazi am'mimba, tinnitus, ugonthi, hyperglycemia, hypoglycemia (makamaka mwa ana), ketoacidosis, kuchepa magazi, kuwonongeka kwa impso (kuchokera ku oliguria kupita ku Nia aimpso insufficiency, hyper- ndi hyponatremia osiyana, hypokalemia), chopinga wa dongosolo chapakati mantha (kusinza, khunyu, kumasokoneza ubongo, chikomokere), encephalopathy poizoni, matenda haematological (yimitsira wa kupatsidwa zinthu za m'mwazi loitanirana kuti coagulopathy, hypoprothrombinemia, ndi elongation nthawi prothrombin).

Ngati munthu ali ndi mankhwala osokoneza bongo okwanira / okhathamira, kuchipatala pamafunika kuchipatala msanga. Gastric lavage, mobwerezabwereza kayendetsedwe ka makala ophatikizika ndi mankhwala ofewetsa thukuta amachitika, ndi ma salicylates oposa 500 mg / l, mkodzo umasakanizidwa ndi kulowetsedwa (iv) kulowetsedwa kwa sodium bicarbonate (88 meq mu 5% shuga yothetsera mlingo wa 1 l, pamlingo wa 10 -15 ml / kg / h). Diuresis amayamba ndi kuchuluka kwa magazi ozungulira kumabwezeretsedwa (mwa kulowetsedwa kawiri kapena katatu mwa kulowetsedwa kwa sodium bicarbonate chimodzimodzi. Tiyenera kudziwa kuti kulowetsedwa kwamadzi kwambiri kwa okalamba kungayambitse matenda a m'mapapo. Acetazolamide ya alkalization wa mkodzo ndi osavomerezeka, chifukwa imatha kupweteka acidemia ndikuwonjezera poizoni wa salicylates.

Mukamachita dialis ya alkaline, pamafunika kukwaniritsa zofunika za pH pakati pa 7.5 ndi 8. Hemodialysis imayikidwa ndi plasma ndende ya salicylates m'magazi oposa 1000 mg / l, komanso mwa odwala omwe ali ndi poizoni wambiri - 500 mg / l kapena kuchepera ngati zikuwonetsedwa (kukulira pang'onopang'ono, Reflexory acidosis, kulephera kwa impso, pulmonary edema, kuwonongeka kwapakati pamitsempha yamagetsi. Poyerekeza ndi mapangidwe am'mimba a edema, mpweya wabwino wa m'mapapo wosakanikirana womwe umapangidwa ndi mpweya wabwino umachitika, ndi edema ya ubongo - hyperventilation ndi osmotic diuresis.

Kuopseza kwa kuledzera kwamphamvu kumakulirakulira achikulire akamagwiritsa ntchito mankhwala kwa masiku angapo pa mlingo woposa 100 mg / kg patsiku. Odwala a m'badwo uno, kuchuluka kwa salicylates mu plasma kuyenera kutsimikizika nthawi, chifukwa nthawi zambiri samazindikira chizindikiro choyambirira cha salicylism, monga kuwonongeka kwam'maso, tinnitus, mseru, kusanza, malaise, mutu, chizungulire.

Malangizo apadera

Supombital iyenera kutengedwa motsogozedwa ndi dokotala.

Pankhani ya kutenga acetylsalicylic acid mu Mlingo wopitilira kuchiritsa, chiopsezo chotenga magazi m'mimba chimakulitsidwa.

Poyerekeza ndi kumbuyo kwa kutenga acetylsalicylic acid panthawi ndi / kapena pambuyo pachitetezo cha opaleshoni, kukula kwa magazi kosiyanasiyana kwamomwe kumatheka. Odwala omwe amalandira Mlingo wochepa wa acetylsalicylic acid, masiku angapo asanachitike opaleshoni yokonzekera, ndikofunikira kuti aziwonetsetsa kuti magazi amatha kutuluka poyerekeza ndi chiwopsezo cha ischemic. Pokhala ndi chiwopsezo chachikulu chokhetsa magazi, mankhwalawo ayenera kusiyidwa kwakanthawi.

Ndi munthawi yomweyo kugwiritsa ntchito thrombital ndi mowa, chiopsezo cha m'mimba kupunduka zolakwika ndi magazi nthawi yayitali.

Pakusala kwakanthawi kochedwa ndi mankhwalawa, kuyezetsa magazi komanso kuyeseza magazi kochita zamatsenga kuyenera kuchitidwa nthawi ndi nthawi.

Mimba komanso kuyamwa

Mu trimesters oyambira a I ndi III, kugwiritsa ntchito Supombital kumatsutsana, chifukwa zimakhala ndi teratogenic. Munthawi yoyamba kubereka, kugwiritsa ntchito mankhwalawa kungayambitse mawonekedwe a kugawanika kwa khomo lapamwamba mu fetus, ndipo chachitatu trimester - kuletsa ntchito (kuponderezana kwa syntaglandin synthesis, pulmonary vascular hyperplasia ndi matenda oopsa m'mitsempha yamagazi.

Salicylic acid imadutsa chotchinga. Mu II trimester yokhala ndi pakati, kumwa mankhwalawa ndikotheka pokhapokha ngati phindu lomwe likuyembekezeredwa kwa mayi lipitilira kuwopsa kwa mwana wosabadwayo.

Acetylsalicylic acid, monga ma metabolites ake, imadutsa mkaka wa m'mawere. Pogwiritsa ntchito thrombital, kuyamwitsa kuyenera kusiyidwa.

Zofanana za Thrombital ndi Cardiomagnyl

Izi ndi zinthu ziwiri. Zosakaniza zogwira ntchito pazomwe zimapangidwira: acetylsalicylic acid (75-150 mg), magnesium hydroxide (15.2 kapena 30.39 mg).

Zotsatira zabwino zimaperekedwa chifukwa cha momwe zimagwirira ntchito. Mankhwala amalepheretsa kaphatikizidwe ka thromboxane A2, kamene kamachepetsa kuthekera kwa mapulateleti kutsatira m'makoma amitsempha yamagazi. Nthawi yomweyo, pamakhala kuchepa pakumanga ma cell am'magazi kwa wina ndi mnzake, mapangidwe amitsempha am magazi amaletsedwa, ndipo mitsempha ya varicose imakhalanso chisonyezo chogwiritsa ntchito. Katundu wa antithrombotic amawonekera mkati mwa masiku 7. Kuti izi zitheke, ndikokwanira kumwa 1 piritsi.

Chuma china cha acetylsalicylic acid ndiko kuthekera kokhala ndi zotsatira zabwino pamtima. Ndi mankhwala omwe ali ndi mankhwalawa, pali kuchepa kwa chiwopsezo cha kufa myocardial infarction. Mankhwala amathandiza kupewa kukula kwa matenda amtunduwu komanso matenda osiyanasiyana a mtima.

Pogwiritsa ntchito mankhwala osokoneza bongo, nthawi ya prothrombin imawonjezeka, kuchuluka kwa njira ya prothrombin yopanga m'chiwindi kumachepa. Kuphatikiza apo, pali kuchepa kwa kuchuluka kwa zinthu zosakanikira (kokha vitamini K-wodalira).

Mukatenga thrombital ndi cardiomagnyl, kuthekera kwa kuphatikiza mapulateleti amitsempha.

Pali milandu ingapo ikuluikulu, pomwe mankhwala amatha kupweteketsa:

• matenda am'mimba,
• kuperewera kwa magazi
• kuchuluka kwa zilonda zam'mimba,
• kupezeka kwa mphumu ya bronchial pamankhwala a NSAIDs,
• kukanika kwa aimpso,
• Mimba mu 1 ndi 3 trimesters,
• kuyamwa
• Hypersensitivity pamagawo a mankhwala,
• wazaka 18
• kulephera kwa aimpso
• mankhwala a methotrexate.

Mankhwala ayenera kumwedwa mosamala kwambiri chifukwa chovulaza mu milandu yotsatirayi:

• gout
• kuchuluka kwa michere ya chiwindi,
• Hyperuricemia
• mbiri ya zilonda zam'mimba komanso magazi,
• Mphumu ya bronchial,
• polyposis m'mphuno,
• chifuwa
• mimba 2 trimesters.

Nthawi zina, kumwa mapiritsiwa kungakhale kovulaza, chifukwa chake, pozindikira zotsutsana, sayenera kunyalanyazidwa. Ngati pali zotsutsana pamilandu, lingaliro lovomera liyenera kuperekedwa ndi adokotala.

Ngakhale kuti mankhwalawa amapindula ndi matenda a mtima ndi mitsempha yamagazi, kusintha minyewa ya mtima, ngati mulingo wambiri utatha, zitha kuyipitsa thanzi. Kuopsa kwa bongo kumawerengeredwa kuti:

1. Yapakatikati. Pali mseru ndi kusanza, tinnitus, hematopoietic dongosolo kusokonekera - kuchuluka magazi, kuchepa magazi. Kumva zoyipa, chisokonezo ndi chizungulire zimachitika. Wodwalayo amasambitsidwa ndi m'mimba ndipo amakhala ndi mlingo wokwanira wa kaboni wokhazikitsidwa. Chithandizo chimatengera chithunzi cha matenda osokoneza bongo.
2. Zovuta. Thupi, chikomokere, kupuma komanso mtima kuchepa, hypoglycemia imadziwika. Chithandizo chimachitika kuchipatala. Wodwalayo akuwonetsedwa kuti ali ndi chithandizo chokwanira, chomwe chimaphatikizapo kuyambitsa njira zapadera zamchere, kuyendetsa digesis ndi kupweteka kwam'mimba, hemodialysis.

Ngati bongo wa thrombital, nseru ndi kusanza, tinnitus zimawonedwa.

Mankhwalawa amalimbikitsa mphamvu ya mankhwala ena, malinga ngati amagwiritsidwa ntchito limodzi:

1. Methotrexate. Kuchepetsa chilolezo, kuwonongeka kwa zomangira ndi mapuloteni.
2. Heparin ndi anticoagulants osadziwika. Mapulatifomu amasintha momwe amagwirira ntchito. Ma Anticoagulants amakakamizidwa kunja kwa maubwenzi awo ndi mapuloteni.
3. Antiaggregant ndi hypoglycemic agents - ticlopidine.
4. Zokonzekera zomwe zimakhala ndi ethanol.
5. Mankhwala a insulin ndi hypoglycemic.
6. Digoxin. Pali kuchepa kwa impso excretion.
7. Valproic acid. Kuukakamiza kumuchotsera ndi ma protein.

Mankhwala amateteza izi:

• uricosuric othandizira
• Maantacid ndi colestyramine.

Ubwino wa mankhwalawa umachepetsedwa tikamamwa ndi Ibuprofen.

Kuyanjana kwa mankhwala osokoneza bongo

Ndi kuphatikiza kwa acetylsalicylic acid kumawonjezera machitidwe a mankhwala / zinthu zotsatirazi chifukwa chopanga zotsatirazi:

• digoxin - impso yake imachepa,
• methotrexate - kufupika kwa impso, ndipo chinthu ichi sichitha kulumikizana ndi mapuloteni, kuphatikiza uku kumawonjezera chiwopsezo cha zovuta zoyipa kuchokera ku ziwalo zopanga magazi,
• antidiabetesic pamlomo wothandizila (sulfonylurea zotumphukira) ndi insulin - acetylsalicylic acid mu okwera chikuwonetsa hypoglycemic zotsatira, zotumphukira sulfonylurea amachotsedwa kulumikizana ndi mapuloteni a plasma a magazi,
• heparin ndi anticoagulants osadziwika - ntchito ya kupatsidwa zinthu za m'magazi ndi kuwonongeka, ma anticoagulants osalunjika amachotsedwa kuti asalumikizane ndi mapuloteni a plasma,
• valproic acid - chinthu ichi sichingasinthidwe kulumikizana ndi mapuloteni a plasma,
• narcotic analgesics, ena NSAIDs, thrombolytic, antiplatelet ndi anticoagulant othandizira (ticlopidine) - kusamala kuyenera kuchitidwa ndi kuphatikiza uku.

Mankhwala acetylsalicylic acid akaphatikizidwa ndi mankhwala / zinthu zina, zotsatirazi zimawonedwa:

• barbiturates ndi mchere wa lithiamu - kuchuluka kwa plasma kwa othandizira awa kumawonjezera,
• ibuprofen - zotsatira za mtima za acetylsalicylic acid zimachepetsedwa zikagwiritsidwa ntchito mu Mlingo mpaka 300 mg chifukwa cha kufooka kwa mphamvu ya antiplatelet, pakakhala chiwopsezo cha matenda amtima, kuphatikiza uku sikulimbikitsidwa,
• anticoagulants, thrombolytics, ma antiplatelet othandizira - chiopsezo chotaya magazi ndi kuchuluka,
• GCS, ethanol ndi mankhwala okhala ndi ethanol - zovuta zoyipa za m'mimba zimawonjezeka, ndipo chiwopsezo cha kukha m'mimba chikuwonjezereka,
• systemic corticosteroids - kuchotsa kwa ma salicylates kumatheka, ndipo zotsatira zake zimafooka, atatha kugwiritsa ntchito systemic corticosteroids, chiopsezo cha kuchuluka kwa salicylates chikuwonjezeka,
• Mowa - poizoni wamavuto amtundu wamkati wamanjenje amawonjezeka,
• colestyramine, ma antacid - mayamwidwe acetylsalicylic acid yafupika,
• kukonzekera kwa uricosuric (phenenicide, benzbromaron) - mphamvu zawo zimachepa chifukwa chopikisana ndi aimpso a chibayo ndi uric acid,
• angiotensin-converting enzyme inhibitors - kuchepa kwa kuchuluka kwa kuchuluka kwa kusefukira kwamasewera kumawonedwa chifukwa cha kuletsa kwa ma prostaglandins, kuwonetsa zotsatira zosapindulitsa ndipo, chifukwa chake, kutsika kwa hypotensive zotsatira,
• diuretics (kuphatikiza waukulu Mlingo wa acetylsalicylic acid) - kuchepa kwa kusefedwa kwa glomerular chifukwa cha kuchepa kwa kupanga kwa ma prostaglandins mu impso ndikotheka.

Zofanizira za Trombital ndi: Cardiomagnyl, Trombital Forte, ThromboMag, Phasostabil.

Ndemanga za Trombital

Ndemanga za Trombital ndi zabwino kwambiri. Odwala amawona kugwira ntchito kwa antiplatelet agent pamene imagwiritsidwa ntchito popewa matenda amtima, kubwereza mobwerezabwereza kwa infarction ya myocardial ndi thromboembolism pambuyo pothandizidwa ndi opaleshoni yamatumbo, komanso kupewa matenda a angina. Malinga ndi ndemanga, mukalandira chithandizo ndimankhwala mumakhala zotsatira zabwino. Komanso, odwala amadziwa chizindikiritso chonse cha mankhwalawa ndi Cardiomagnyl wakunja, koma mtengo wa mankhwalawa ku Russia ndi wotsika pang'ono kuposa mnzake, zomwe ndizofunikira kwa odwala pakulandila kwakanthawi.

Zoyipa za mankhwalawa zimaphatikizapo mndandanda waukulu wa contraindication ndi zovuta zomwe zimachitika. Kuti achepetse mavuto osagwirizana ndi chakudya cham'mimba, odwala ambiri amalimbikitsa kuti azidya pambuyo chakudya.

Khalidwe la Trombital

Wopanga - Pharmstandard (Russia). Njira yotulutsira mankhwalawa ndi mapiritsi okhala ndi filimu. Ichi ndi chida cha magawo awiri. Zosakaniza zogwira ntchito zake: acetylsalicylic acid (75-150 mg), magnesium hydroxide (15.20 kapena 30.39 mg). Kuphatikizika kwa zinthuzi kukuwonetsedwa piritsi limodzi. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa:

• kuphatikiza
• antithrombotic.

Kuti mudziwe chomwe chili bwino, thrombital kapena cardiomagnyl, ndikofunikira kuyesa kuchuluka kwa mankhwalawa.

Zotsatira zabwino zimaperekedwa chifukwa cha momwe zimagwirira ntchito. Mankhwala amalepheretsa kaphatikizidwe ka thromboxane A2, kamene kamachepetsa kuthekera kwa mapulateleti kutsatira m'makoma amitsempha yamagazi. Nthawi yomweyo, pamakhala kutsika kwenikweni pakumanga ma cell amwazi wina ndi mnzake, mapangidwe amitsempha am magazi amaletsedwa. Katundu wa antithrombotic amawonekera mkati mwa masiku 7. Kuti izi zitheke, ndikokwanira kumwa 1 piritsi.

Werengani zambiri za mankhwala aliwonse omwe alembedwa:

Chuma china cha acetylsalicylic acid ndiko kuthekera kokhala ndi zotsatira zabwino pamtima. Ndi mankhwala omwe ali ndi mankhwalawa, pali kuchepa kwa chiwopsezo cha kufa myocardial infarction. Mankhwala amathandiza kupewa kukula kwa matenda amtunduwu komanso matenda osiyanasiyana a mtima.

Ndi chithandizo cha thrombital, nthawi ya prothrombin imachulukanso, kulimba kwa njira ya prothrombin kupanga mu chiwindi kumachepa. Kuphatikiza apo, pali kuchepa kwa kuchuluka kwa zinthu zosakanikira (kokha vitamini K-wodalira).

Katundu wa antithrombotic amawonekera mkati mwa masiku 7. Kuti izi zitheke, ndikokwanira kumwa 1 piritsi.

Mankhwala othandizira opatsirana muyezo uyenera kuchitika mosamala ngati maanticoagulants ena atchulidwa nthawi yomweyo. Chiwopsezo cha zovuta zimachuluka, kutuluka kwa magazi kungatseguke.

Kuphatikiza apo, zinthu zina za acetylsalicylic acid zimawonetsedwanso: anti-yotupa, antipyretic, analgesic. Chifukwa cha izi, thrombital ikhoza kugwiritsidwa ntchito kuchepetsa kutentha kwambiri kwa thupi, kupweteka kwa maumboni osiyanasiyana, motsutsana ndi maziko omwe amapanga kutupa kwa mtima. Chuma china cha mankhwalawa ndi kuthekera kwakwe kupititsa patsogolo mayendedwe a uric acid.

Zoyipa zamankhwala zimaphatikizira zovuta pa mucous membrane wa ziwalo zam'mimba. Kuchepetsa mphamvu ya acetylsalicylic acid ndikupewa kukula kwa zovuta, gawo lina linayambitsidwa ndikuyambitsa - magnesium hydroxide. Zisonyezero zogwiritsa ntchito thrombital:

• kupewa mtima ndi mtima matenda komanso kupewa mtima kulephera,
• kupewa magazi
• kupewa thromboembolism pambuyo opaleshoni yamadzi,
• Kuchepetsa chiwopsezo cha kukonzanso kwa myocardial infarction,
• angina pectoris wachikhalidwe chokhazikika.

Cardiomagnyl Zochita

Cardiomagnyl amapangidwa ndi Takeda GmbH (Germany).

Fomu ya Mlingo: mapiritsi okhala ndi mphamvu.

Zosakaniza: Acetylsalicylic acid - 75/150 mg, magnesium hydroxide - 15.2 / 30.39 mg.

Omwe amathandizira: cellcrystalline cellulose, wowuma chimanga, wowuma wa mbatata, magnesium stearate.

Phula: methylhydroxyethyl cellulose, propylene glycol, talc.

Kodi pali kusiyana kwanji pakati pa Thrombital ndi Cardiomagnyl?

Mankhwalawa ali ofanana Mlingo wa yogwira - acetylsalicylic acid (ASA), komanso antacid - magnesium hydroxide. Limagwirira a zochita za mankhwalawa zimatengera mtundu-zimadalira mtundu wa zotsatira za ASA pa thupi.

Mlingo wochepa, acetylsalicylic acid amawonetsa antiplatelet katundu, i.e. amatha kuonda magazi.

ASA pa mlingo wa 30-300 mg / tsiku. sasintha mosemphana ndi ma enzymes cycloo oxygenase (COX), omwe amathandizira popanga thromboxane A2. Katunduyu wa ASA amagwiritsidwa ntchito popewa matenda amtima omwe amakhudzana ndi kuwonjezeka kwamitsempha yamagazi: thromboembolism, stroke ischemic ndi infarction ya myocardial.

Mwa zina zoyipa za ASA, choopsa chachikulu ndikuwonjezereka kwa kukokoloka ndi zilonda pamakoma am'mimba ndi duodenum. Izi osayenerera zotsatira zimagwirizanitsidwa ndi chopinga cha ma cell a zotumphukira maselo atatseka ma enzymes a COX, omwe samangophatikizidwa ndi kapangidwe ka thromboxane A2, komanso kapangidwe ka prostaglandins (PG). Kuletsa kwa kapangidwe ka GHG kumatchulidwa kwambiri mutatenga waukulu Mlingo wa ASA (4-6 g), koma minofu yolumikizika ya cytoprotection imadziwika mukagwiritsa ntchito waukulu.

Kuteteza makoma am'mimba, mapiritsi a Trombital ndi Cardiomagnyl adakutidwa ndi enteric film comping, kapangidwe kake kamene kamakhala ndi kosagwirizana komwe sikukhudza chitetezo chawo.

Magawo omwe amagwira ntchito a mankhwalawo alibe kusiyana pakapangidwe kapena mulingo, chifukwa chake, zomwe zikuwonetsa kumwa mankhwalawa ndizofanana ndendende:

1. Prophylaxis yoyamba ya thrombosis ndi mtima pachimake kutha kwa zinthu zoopsa (matenda ashuga, matenda oopsa, matenda oopsa, kunenepa kwambiri, kusuta, zaka zoposa 50).
2. Kupewa kwa sekondale myocardial infarction ndi thrombosis.
3. Kupewa kwa thromboembolism pambuyo pakuchita opaleshoni ya mtima.
4. Angina pectoris.

Zoyipa zomwe zimamwa mankhwalawa ndi:

• tsankho kwa NSAIDs, makamaka ASA,
• zilonda zam'mimba pachimake kapena mu anamnesis,
• chizolowezi chokhetsa magazi m'mimba,
• Mphumu ya bronchial,
• polyposis ya mucosa amphuno,
• hemophilia
• hemorrhagic diathesis,
• hypoprothrombinemia,
• stratified aortic aneurysm.

Chotsika mtengo ndi chiyani?

Poyerekeza, tebulo likuwonetsa mitengo ya mankhwalawa amitundu mitundu yotulutsidwa:

Domestic Thrombital ndiwotsika mtengo wogwiritsira ntchito antiplatelet kuposa mnzake waku Germany.

Kodi ndizotheka m'malo mwa thrombital ndi cardiomagnyl?

Mankhwalawa amatha kusinthidwa panthawi yopereka chithandizo chamankhwala, popeza alibe kusiyana pakapangidwe kake. Zizindikiro zogwiritsidwa ntchito ndi contraindication ndizofanana.

"

Marinov M. Yu., Therapist, Verkhoyansk: "Kupezeka kwa mankhwalawa, kumbali imodzi, kuli bwino kwa wodwalayo, koma, kumawonjezera mwayi wolakwitsa pakudzipanga nokha. Mankhwalawa amagwiritsidwanso ntchito pothana ndi vuto la odwala omwe ali ndi mitsempha ya varicose kapena ngozi ya cerebrovascular. "Kutsiliza kwa maphunziro a prophylactic kuyenera kuchitika pang'onopang'ono moyang'aniridwa ndi dokotala. Ndikukana kwambiri mankhwala, pamakhala chiwopsezo chowonjezeka magazi.

Alina, wazaka 24, ku Moscow: "Mankhwalawa onse ndi othandizira mapiritsi osavuta a Acetylsalicylic acid - chida chotsika mtengo, koma chovuta kugwiritsa ntchito kuti muchepetse magazi. Nembanemba imateteza bwino m'mimba, ndikuchotsa mbali yayikulu."

Olga, wazaka 57, Barnaul: "Ndidadzisankhira Cardiomagnyl koyambirira kwa prophylaxis. Koma kenako ndidasinthanitsa ndi Trombital. Sindimamva kusiyana kulikonse. Sindinawone zovuta zilizonse. Pali mitundu yambiri yamankhwala awa."

Kodi pali kusiyana kotani pakati pa Thrombital ndi Cardiomagnyl

Supombital imapangidwa mapiritsi okhala ndi tinthu tambiri, omwe amachepetsa kuchuluka kwa zoyipa pamimba. Cardiomagnyl imapezeka m'mapiritsi osavomerezeka, chifukwa chake, acetylsalicylic acid imachita mwankhanza pa mucosa ya m'mimba.

Kusiyanitsa mtengo ndikochepa. Phukusi la Trombital (mapiritsi 30) limatenga pafupifupi ma ruble 115, Cardiomagnyl - ma ruble 140.

The kapangidwe ndi Mlingo wa mankhwalawa ndi ofanana, kotero ali ndi zofanizira komanso contraindication. Supombital imakonda kwambiri pochiza matenda amtima chifukwa cha mavinidwe a mafilimu.

Ndemanga za Madotolo za Trombital ndi Cardiomagnyl

Dmitry, dokotala wa opaleshoni ya mtima, Moscow

Thrombital nthawi zonse zotchulidwa kwa odwala mtima. Mlingo - 75 mg kamodzi tsiku lililonse chakudya chamasana. Chidwi chachikulu komanso chotsika mtengo. Mankhwala oyenera mu opaleshoni ya mtima. Odwala onse amakhutira ndi mtengo ndi mtundu wa mankhwalawo.

Vladimir, dokotala wamtima, St.

Cardiomagnyl ali ndi Mlingo wa 75 mg, womwe ndi mlingo wochepetsetsa womwe umathandiza kuchepetsa chiopsezo cha myocardial infarction ndi stroke. Kutsitsa zomwe zili ndi ASA mu mankhwalawa, kumachepetsa mwayi wotulutsa magazi. Chifukwa chake 75 mg ndiyabwino pankhaniyi kuposa 100 mg. Pankhaniyi, Cardiomagnyl imatha kungochiritsa zakukula mwa odwala.

Igor, phlebologist, Vladivostok

Mtengo wotsika wa mankhwalawa, kuthamanga kwambiri poyerekeza ndi kupewa matenda amtima komanso zovuta zawo, ochepa kuchuluka kwa zotsatira zoyipa, kumwa kamodzi patsiku. Cardiomagnyl ndi mankhwala ofunikira kwambiri pakuchita opaleshoni ya mtima, omwe amalembedwa kwa odwala onse a 50+ omwe ali ndi mtima wamitsempha kuti apewe kukwiya, kugunda kwa mtima ndi mtima.

Cardiomagnyl imapezeka m'mapiritsi osavomerezeka, chifukwa chake, acetylsalicylic acid imachita mwankhanza pa mucosa ya m'mimba.

Ndemanga za Odwala

Marta, wazaka 34, Yaroslavl

Anatenga Trombital Forte (ndi muyeso wokwanira wa zinthu zofunikira). Zotsatira zoyipa zidawonekera: kusokonezeka kwa tulo, kupweteka mutu, chizungulire, nseru. Ndinasinthira ku Trombital ndi mlingo wocheperako wa zinthu zikuluzikulu. Analandila chithandizo popanda zovuta.

Alena, wazaka 36, ​​Nizhny Novgorod

Ndakhala ndikumwa Cardiomagnyl kwazaka zopitilira 3. Panalibe zovuta kuchokera ku mankhwalawa. Botolo limatha miyezi itatu. Ndimamwa piritsi limodzi patsiku, ndimagula mapiritsi 100, ndi 75 mg. Imayenera kuledzera pafupipafupi, chifukwa ndili ndi hemodialysis, pali fistula, ngati simumamwa, magazi amawoneka. Kenako sikungakhale kotheka kuchita njira ya hemodialysis. Pokhapokha mutayika catheter, koma amathanso kutsekedwa. Chifukwa chake, ndimamwa mosalekeza, zimathandiza, mankhwala abwino.

Victoria, wazaka 32, Volgograd

Mankhwalawa adatengedwa panthawi yomwe ali ndi pakati, chifukwa placenta sadaperekedwe bwino ndi magazi ndipo kubadwa msanga kumatha kuyamba, pa mlingo wa 75 mg kamodzi patsiku atatha kudya kwa miyezi iwiri. Munthawi imeneyi, kunalibe zovuta pamimba, ma mphuno zokhazokha zomwe zimakonda kukhala pafupipafupi. Koma popeza kuwongolera kudawonekera pa ultrasound, ndiye kuti ndudu m'mphuno chifukwa cha mwana zimatha kuloledwa.

Makhalidwe a Thrombital ndi Cardiomagnyl

Gawo logwira la Cardiomagnyl ndi acetylsalicylic acid. Kulowera m'magazi, kumalepheretsa kupanga kwa thromboxane (mapulateleti omwe amamangika pamodzi motsogozedwa ndi enzyme iyi, zomwe zimapangitsa kuti akhale ndi thrombosis).

Chowonjezera china pakuphatikizaku ndi magnesium hydroxide. Ndi antacid (chinthu chomwe chimatsitsa acidity m'mimba).

Kuphatikizidwa kwa acetylsalicylic acid ndi magnesium hydroxide, sikuwonetsa katundu wake woipa komanso sikuwononga nembanemba ya mucous. Ubwino wofunikira ndikuchepa kwa kuyanjana kwa zigawozo, chifukwa chomwe zimalowa mu magazi momasuka.

Kuphatikizika kwa Trombital kumaphatikizanso magawo omwewo. Mphamvu ya kumwa imapitirira sabata pambuyo pa makonzedwe. Zofunika! Zinthu zomwe zimagwira zimachepetsa chiopsezo cha kuchepa kwa myocardial infaration. Amapereka komanso kugwira ntchito mwamphamvu poletsa matenda a sitiroko. Mu mlingo wapamwamba, amakhala ndi zotsutsana ndi zotupa komanso analgesic.

Kuyerekeza: kufanana ndi kusiyana

Mankhwala omwe afunsidwa ali ndi zochitika zambiri. Zowonetsera zagwiritsa ntchito motere:

1. Kupewa komanso kuchiza matenda a thrombosis.
2. Chithandizo cha thromboembolism pambuyo pakuchita opaleshoni ya mtima.
3. Kukhalapo kwa angina osakhazikika.

Mukuyenera kukumbukira! Ngati imodzi mwazithandizo sizili bwino kwa wodwala, ndikosayenera kuisintha ndi analog. Kupanda kutero, hypersensitivity imayamba.

Contraindication ogwiritsa ntchito ali motere:

1. Kuphika magazi ndi kuwonda kochepa.
2. Mbiri ya mphumu.
3. Kulephera kwakukulu kwaimpso.

Yang'anani! Sizoletsedwa kugwiritsa ntchito mankhwalawa kwa odwala osakwana zaka 18. Ndikofunika kusiya kugwiritsa ntchito nthawi yoyamba komanso yachitatu ya mimba, chifukwa ndiye kuti kupangika kwa ziwalo za mwana wosabadwayo kumachitika (kumalepheretsa njirayo).
Amayi oyembekezera amatha kugwiritsa ntchito mapiritsi awa kwakanthawi kochepa, chifukwa mchere umalowa mkaka.

Kusiyanako kwalembedwa pagome:

Mlingo wovomerezeka ndi dokotala uyenera kuonedwa kuti mupewe mankhwala osokoneza bongo, limodzi ndi kusanza, tinnitus. Zizindikirozi zikaonekera, muyenera kutsuka m'mimba yanu.

Kodi bwino Cardiomagnyl kapena Thrombital

Mukamasankha malonda, muyenera kuganizira kufunika kopera musanagwiritse ntchito. Ngati pakufunika izi, ndibwino kusankha Cardiomagnil, chifukwa ili ndi zoopsa.

Mankhwala onse awiriwa alibe shuga. Chifukwa chake amatha kudyedwa ndi odwala matenda a shuga. Zofunika! Zosakaniza zomwe zimapangidwa muzomwe zimapangidwira zimathandizira Heparin ndi Digoxin. Sitikulimbikitsidwa kuphatikiza mankhwala ndi anticoagulants. Kupanda kutero, magazi amatha.

Tsimikizirani kupambana kwa mayankho ochokera kwa ogwiritsa ntchito ndipo madokotala angakuthandizeni.

Kuchokera ku angina pectoris, adotolo adalangiza Cardiomagnil. Ndinali wokondwa kuti samangoletsa mwachangu zizindikiro za matendawa, komanso mulibe shuga (ndili ndi mbiri ya matenda ashuga).

Kodi pali kusiyana kotani pakati pa mkulu wachitetezo ndi wofufuza: ntchito ndi chiyani, kusiyana. Onani zambiri apa.

Kuyambira thrombosis, dokotala adafotokozera thrombital. Ubwino wake ndi mtengo wotsika mtengo komanso wogwira ntchito mankhwalawa komanso kupewa matenda amtima.

Zochizira matenda amtima, ndimapereka mankhwala a Trombital kapena Cardiomagnil kwa odwala. Kupezeka kwa ma contraindication kuti agwiritse ntchito kumathetsedwa ndi mtengo wokwera mtengo komanso wogwira ntchito.

Onani malangizo akanema akukonzekera "Cardiomagnyl":

Kusiyana kwa Trombital ndi Cardiomagnyl

Mukamasankha Trombital kapena Cardiomagnyl kukonzekera, muyenera kudziwa bwino zomwe ali nazo, mawonekedwe ake ndi kusiyana kwawo. Pankhaniyi, kusankha kwa mankhwala kuyenera kupangidwa ndi adokotala.

Mukamasankha Trombital kapena Cardiomagnyl kukonzekera, ndikofunikira kuti adziwe mawonekedwe awo, mawonekedwe ndi kusiyana kwawo.

Kodi kusiyana ndi kufanana kwa Trombital ndi Cardiomagnyl ndi kotani?

Mankhwala ali ndi mawonekedwe ofanana. Zizindikiro ndi zoletsa kugwiritsa ntchito mankhwalawa ndizofanana.

Mankhwala Trombital amapezeka piritsi. Pankhaniyi, mapiritsiwa amakhala ndi zokutira, chifukwa chomwe chiopsezo cha zotsatira zoyipa za ziwalo za m'mimba zimachepetsedwa.

Mapiritsi a Cardiomagnyl mapiritsi alibe utoto wamafilimu, chifukwa chake acetylsalicylic acid, motsutsana ndi momwe amagwiritsidwira ntchito, amakhala ndi vuto lalikulu pamatumbo.

Malingaliro a madotolo

Igor (phlebologist), wazaka 38, Syktyvkar

Mankhwalawa amachepetsa magazi ndikuletsa kukula kwa mtima wama mtima ambiri. Nthawi zambiri, ndimapereka mankhwala opatsirana chifukwa mankhwalawa amaphatikizidwa ndi zokutira zapadera, zomwe zimapangitsa kuti mankhwalawo akhale otetezeka. Cardiomagnyl ndi wotsika mtengo. Komabe, sindingalangize kupulumutsa paokha thanzi. Komanso, kusiyana kwa mtengo ndikochepa.

Dmitry (dokotala), wazaka 40, Vladimir

Mankhwala onse awiriwa amagwira ntchito kwambiri. Amasiyana mokha - kupezeka kwa nembanemba wamafuta mu mankhwala Trombital. Cardiomagnyl alibe, chifukwa chake iyenera kumwedwa mosamala ndi kuyang'aniridwa ndi dokotala. Zithandizozi zimathandizidwa bwino ndi odwala matenda ashuga komanso odwala okalamba. Zotsatira zoyipa sizimawoneka ngati mumatsatira malangizo azachipatala ndi zofunikira za malangizo.

Zizindikiro ndi contraindication kuti mugwiritse ntchito

Cholinga cha mankhwalawa ndi mankhwalawa ndikuwongolera magwiridwe antchito a mtima, kupewa mapangidwe a magazi.

Mankhwalawa amathandizidwa kuti apewe matenda pofuna kupewa mavuto omwe angabwere chifukwa cha omwe ali m'gulu la anthu omwe ali pachiwopsezo (omwe ali ndi vuto la kunenepa kwambiri, matenda a shuga, matenda oopsa, komanso magulu okalamba komanso osuta).

Mankhwala amapatsidwa thrombosis

Kuphatikiza pa chithandizo chachikulu, mankhwalawa amatha kuikidwa pambuyo pakuchita opaleshoni (kuphatikizapo coronary artery bypass grafting). Kugwiritsa ntchito mankhwalawa panthawi yothandizirana zimathandizira kuchepetsa kwakukulu pakuchitika kwa thrombosis.

Trombital ikusonyezedwa kwa odwala:

• ndiina wosakhazikika,
• kupewa mapangidwe a thrombosis pambuyo pa opaleshoni,
• Ndi kukula kwa mtima ndi matenda a mtima,
• popewa kupangika kwa myocardial infarction,
• motsutsana ndi maziko a kulephera kwa mtima pachimake,
• kuteteza mapangidwe magazi m'ziwiya.

Chipangizocho chili ndi zoletsa zina pakugwiritsa ntchito. Sichikulimbikitsidwa kugwiritsa ntchito mapiritsi a anthu omwe ali ndi vuto lotaya magazi (motsutsana ndi maziko a thrombocytopenia, kusowa kwenikweni kwa vitamini K, hemorrhagic diathesis).

Ndi zoletsedwa kotheratu kutenga odwala omwe ali ndi vutoli kwa aspirin, omwe si mankhwala a antiidal, komanso gawo lililonse la mankhwalawo. Chida ichi sichimagwiritsidwa ntchito ngati ana, sichothandiza ana.

Kuphatikiza apo, chida sichingatengedwe pamaso pa zinthu izi:

• kutaya magazi
• kuchepa kwa magazi m'mimba kapena matumbo,
• kulephera kwa mtima 3 ndi FC, ikuyenda mozungulira.
• kukanika kwambiri kwa hepatic ndi aimpso,
• Mphumu ya bronchial yophatikizidwa ndi kusawona kwa acetylsalicylic acid,
• matenda a ulcerative etiology mu ziwalo zam'mimba khunyu,
• azimayi pa nthawi yobereka komanso poyamwitsa.

Malangizo ogwiritsira ntchito

Kulandila kuyenera kuchitika ndi njira ya pakamwa kamodzi patsiku. Ngati mukuvutika kumeza mankhwala onse, mutha kuwabaya kapena kuwaza musanagwiritse ntchito.

Mlingo wa mankhwalawa chifukwa cha chifukwa chomwe amalembera komanso kufotokozedwera patebulopo:

Zofunika! Mankhwala othandizira opatsirana mwa mankhwalawa amayenera kugwiritsa ntchito nthawi yayitali, kuchuluka kwa nthawi ya maphunzirowo kuyenera kutsimikiziridwa ndi adokotala.

M'pofunika kugwiritsa ntchito mankhwalawa, kutsatira mosamalitsa malangizo akuchipatala.

Thrombital ndi Cardiomagnyl: kusiyana kwake ndi kotani

Malinga ndi zomwe zimapezeka, kuchuluka kwa zosakaniza, zomwe zikuwonetsa komanso kutsutsana kwa ntchito, thrombital ndi mtima ndi ma analogues. Koma chifukwa chakuti mapiritsi a Trombital ali ndi membala wamakanema oteteza, amawakonda poyerekeza ndi Cardiomagnyl pochiza matenda a ziwalo zamagetsi mothandizidwa ndi mtima, chifukwa zimakhudza kwambiri dongosolo logaya chakudya.

Mitengo ndi nyengo ya tchuthi ku malo ogulitsa mankhwala

Mutha kugula zambiri m'mitundu iliyonse mopanda mankhwala kuchokera kwa dokotala. Mtengo wa mankhwalawa umatheka chifukwa cha kuchuluka kwake ndi kuchuluka kwa mapiritsi omwe ali phukusili, ndipo pafupifupi ma ruble 92-157.

Kuchita bwino kwa Trombital pothana ndi mavuto amtima komanso njira zodzitetezera kumatsimikiziridwa ndi kuwunika kokwanira kwa anthu omwe adagwiritsa ntchito mankhwalawa. Chida chimathandizira kuchepetsa chiwopsezo cha thrombosis, kusintha magwiridwe antchito a mtima, kuletsa kukula kwa kulowerera kwa mtima mwa anthu omwe ali pachiwopsezo.