Glucophage analogs mapiritsi

Kuti mukhale ndi thanzi labwino mu shuga mellitus, ndikofunikira kuti musangotsatira zakudya zapadera, komanso kumwa mankhwala ochepetsa shuga nthawi zonse.

Nthawi zambiri, madokotala amatipatsa shuga. Mankhwalawa ndi othandiza komanso okwera mtengo. Koma osati nthawi zonse m'mafakitala.

Chifukwa chake, muyenera kudziwa zomwe Glyukofazh ali ndi fanizo, komanso momwe mankhwalawa ali bwino kusintha mankhwalawa. Nkhaniyi ikutiuza.

Zotsatira za mankhwala

Glucophage ndi mankhwala achi French apakamwa a hypoglycemic. Amapezeka mu mawonekedwe a mapiritsi oval biconvex. Magawo onse awiriwa amalekanitsidwa ndi chiwopsezo chochepa kwambiri ndipo ali ndi zolemba za "1000", "850" kapena "500" (zomwe zikufanana ndi mlingo wa mankhwalawo).

Chosakaniza chophatikizacho ndi metformin hydrochloride. Ili ndi kuchuluka kwa 1000, 850 kapena 500 mg. Kuphatikiza pa chinthu chachikulu chomwe chimagwira, pali zinthu zothandiza: povidone, hypromellose ndi magnesium stearate. Kutsitsa kwa shuga kumachitika pokhapokha ngati pali hyperglycemia. Kwa odwala omwe ali ndi shuga wathanzi, mankhwalawa samachepetsa kuchuluka kwa shuga m'magazi.

Limagwirira ntchito amatengera luso la metformin poletsa glycogenolysis ndi gluconeogeneis, kuonjezera mphamvu ya maselo kuti apange insulin, ndikuchepetsa kuyamwa kwa glycogen m'matumbo am'mimba. Metformin imathandizanso kukhala ndi lipid metabolism, kutsitsa cholesterol, triglycerides ndi ochepa kachulukidwe lipoproteins.

Dokotala amasankha payekha payekha kwa wodwala aliyense. Mlingo woyamba wa akulu tsiku lililonse ndi 500-100 mg. Pambuyo pa milungu iwiri, ngati pakufunika, imawonjezeka mpaka 1500-2000 mg patsiku. Mlingo wapamwamba ndi 3000 mg.

Zotsatira zoyipa nthawi zina zimaphatikizapo:

• kuchepa kapena kusowa kwa chakudya,
• nseru
• kulawa kwazitsulo mkamwa
• kusanza
• kudzimbidwa.

Nthawi zambiri, zizindikirozi zimawonekera koyambirira kwa chithandizo ndipo pakapita nthawi yochepa pazokha. Pofuna kuchepetsa mavuto, muyeso wa tsiku ndi tsiku umagawidwa pazipinda zitatu. Ngati vuto la dyspeptic silichoka, ndibwino kusiya mankhwalawo.

Pa mankhwala, nthawi zina pamakhala zovuta za mapangidwe a magazi ndi kagayidwe. Nthawi zina, sayanjana mu mawonekedwe a urticaria amawonedwa. Ndi zochitika zotere, mapiritsi amayimitsidwa.

Kodi ndiyenera kusintha pa analogi?

Mtengo wa Glucofage ndiolandiridwa. Paketi ya mapiritsi 30 okhala ndi kuchuluka kwa 500 mg yogwira ntchito amagulitsidwa kuzipatala zamzindawu kwa ma ruble 100-130.

Malinga ndi kuwunika kwa makasitomala, mankhwalawo:

• zosavuta kunyamula
• bwino Sachita plasma shuga
• Matumbo glycemia,
• kukonza bwino kwathunthu,
• amachepetsa thupi
• amathetsa zizindikiro za matendawa.

Chifukwa chake, ndi ochepa omwe amaganiza zopeza fanizo la mankhwalawa.

Pali nthawi zina pomwe pakufunika kusintha glucophage ndi hypoglycemic ina. Izi zitha kuchitika pazifukwa zosiyanasiyana:

• mankhwalawa amalembetsedwanso motero sagulitsidwa kwakanthawi m'mafakisi,
• mapiritsi sakukwanira, amayambitsa zovuta zingapo,
• wodwala akufuna kupeza mankhwala otsika mtengo othandizira.

Ndikofunika kwa odwala matenda ashuga kudziwa zomwe zimalowa m'malo mwa hypoglycemic. Izi zikuthandizani kusankha mwachangu mankhwala oyenera.

Kodi ndimafanizo ati?

Opanga mapiritsi a hypoglycemic a gulu la Biguanide amapereka mitundu yambiri yosanja. Mtengo wawo ukhoza kukhala wosiyanasiyana kapena wotsika.

Zotsatira zabwino kwambiri za mankhwalawa Glucofage ndi awa:

• Reduxin Met (ma ruble 2),
• Metformin (ma ruble 80),
• Formetin (ma ruble 77),
• Metformin-Teva (ma ruble 94)
• Metformin Canon (ma ruble 89),
• Meglift (ma ruble 7).

Chifukwa cha kuchuluka kwa mapiritsi okhala ndi metformin, anthu ambiri omwe amapezeka ndi matenda ashuga ali ndi funso: kodi analogue ndiyabwino bwanji? Kuti muyankhe, muyenera kuphunzira momwe mankhwalawo amathandizira komanso kudziwa za ogula.

Chofunikira chachikulu cha Siofor ndi metformin hydrochloride mu mlingo wa 500 mg. Zabwino zimayimiriridwa ndi povidone, titanium dioxide, hypromellose, macrogol 6000, magnesium stearate. Poyerekeza kapangidwe kazomwe zimapangidwira, ndizosavuta kunena kuti Glucophage ndiyabwino kuposa Siofor.

Mapiritsi a Siofor 850 mg

Popeza ili ndi zowonjezera zochepa. Komanso, nthawi yayitali imayenera kutchedwa mwayi wake: imakhala ndi shuga m'magazi kwa maola 10. Siofor amasiya kugwira ntchito patatha mphindi 30.

Otsatirawa ndi omwe akukonda Glucophage:

• sizimapangitsa kusintha kwakukuru mu plasma glucose,
• imakhala ndi zovuta zochepa kuchokera m'matumbo am'mimba,
• zotsika mtengo
• kumwa mapiritsi pafupipafupi.

Reduxin ndi magome awiri. Yoyamba ili ndi metformin hydrochloride 850 mg, yachiwiri imakhala ndi subutramine hydrochloride monohydrate 10 mg ndi microcrystalline cellulose 158,5 mg.

Omwe amathandizira ndi povidone, gelatin, stearate ya magnesium, sodium ya croscarmellose, madzi osungunuka, calcium yochepa.

Makapu a Reduxine 10 mg

Piritsi lachiwiri likuwonetsa matsenga, kutulutsa ziwalo. Amasintha kagayidwe. Amatengedwa kawiri patsiku. Kapilatini wokhala ndi Metformin amaledzera kamodzi patsiku.

Reduksin endocrinologists nthawi zambiri amalembedwa kwa odwala matenda ashuga kuwonda. Chifukwa chake, ngati palibe kunenepa kwambiri, simuyenera kumwa mankhwalawa. Ndikwabwino kusankha gawo limodzi Glucophage yokhala ndi mavuto ochepa.

Mphamvu yogwira ya Metformin ndi metformin hydrochloride. Mlingo ndi 500, 850 ndi 1000 mg. Zothandizira zothandizira zimayimiriridwa ndi povidone, wowuma 1500, magnesium stearate, opadra 2, croscarmellose sodium, microcrystalline cellulose.

Mapiritsi a Metformin 850 mg

Chifukwa chake, pali zinthu zowonjezera m'mapiritsi awa kuposa Glucofage. Zomwe zimayenera kuphatikizidwa ndi mankhwala ochepetsa. Mwayi ungatchedwa mtengo wotsika mtengo kwambiri.

Kafukufuku akuwonetsa kuti kuphwanya kwa magwiridwe antchito oyendetsa thupi pakudya Metformin kumachitika nthawi zambiri kuposa momwe tingagwiritsire ntchito mankhwala a Glucofage. Chifukwa chake, akatswiri a endocrinologists samalimbikitsa kuti asankhe analogueyi.

Glformin ndi chithunzi cha zopangidwa ku Russia. Ili ndi chinthu chomwechi. Piritsi limodzi lili ndi 250 kapena 500 mg ya metformin.

Palinso zinthu zina zotsatirazi: stearic acid, dihydrate, calcium phosphate, povidone, sorbitol. Kapangidwe ka mankhwala a Glucophage kuli bwino. Popeza glyformin imagulitsidwa pamiyeso yaying'ono, ndikofunikira kumwa pafupipafupi. Nthawi yomweyo, mtengo wa ma CD ndi wokwera.

Kodi mungapeze bwanji analogue?

Glucofage imakhala ndi mitundu yambiri. Mukamasankha wogwirizira, munthu ayenera kuganizira osati mtengo wokhawo, komanso dziko lakapangidwe, mbiri ya wopanga. Mankhwala apakhomo ndi otsika mtengo poyerekeza ndi akunja, pomwe sikugwira ntchito moyenera.

Pali njira zitatu zopezera cholowa m'malo, podziwa chinthu chomwe chikugwira:

• pitani pa webusayiti ya State Register of Medicines ndipo mu gawo la “International Nonpuffetary Name” lowetsani “metformin hydrochloride”. Dinani pa batani la "Pezani". Mndandanda wamankhwala omwe ali ndi metformin ndi zinthu zina zingapo zomwe zidzaonekera. Gome lotsatiralo liyenera kusanjidwa kuti mupeze mndandanda wa mankhwalawa omwe amangotengera metformin. Kuti muchite izi, dinani ulalo womwe uli pamutu pa tebulo, kenako pa "Zina Lamalonda",
• pitani patsamba la zilembo zamagulu azigawo zomwe muli nazo ndipo mu "M" sankhani ulalo "Me". Mndandanda wazinthu zoyambira ndi Ine umawonekera. Muyenera kupeza metformin pamndandandawu ndikudina. Tsamba lokhala ndi mafotokozedwe atsatanetsatane lidzatsegulidwa. Pansipa pali mndandanda wa mankhwala omwe ali ndi ichi,
• pitani pa webapteka.ru. Pitani patsamba "Mndandanda wazinthu zopanga mankhwala". Lowani "metformin hydrochloride" mu mawonekedwe olowera. Dinani batani la "Pezani". Gome limawonekera ndi dzina la mankhwalawo, chomwe chimagwira ntchito chomwe ndi metformin.

Pomwe pali mndandanda wamankhwala ochepetsa shuga omwe amachokera pa metformin, zimangokhala kuti mudziwane ndi malangizo a mankhwala aliwonse ndikusankha njira yoyenera kwambiri.

Makanema okhudzana nawo

About Metformin, Siofor, Glucofage kukonzekera mu kanema:

Chifukwa chake, Glucophage, malinga ndi odwala omwe ali ndi vuto la matenda ashuga, ndi njira yothandiza kwambiri kufotokozera msambo wa glycemia. Mapiritsi ndiwotsika mtengo, amakhala ndi zovuta zochepa. Koma pazifukwa zosiyanasiyana, nthawi zina ndikofunikira kusintha chida ichi ndi analog.

Pali mankhwala ambiri ozikidwa pa metformin. Gliformin amadziwika kuti ndiye wabwino kwambiri. Ilinso ndi mawonekedwe ofanana, koma ochepa contraindication. Zowona, zimawononga ndalama zambiri. Cheker ndi Fomu ndi Reduxine. Sikoyenera kuti mupange chisankho pakusintha kwina nokha. Izi zikuyenera kuchitika ndi endocrinologist.

• Imakhazikika pamisempha ya shuga kwa nthawi yayitali
• Imabwezeretsa kapangidwe ka insulin

Phunzirani zambiri. Osati mankhwala. ->

Mndandanda wamalo omwe akupezeka a Glucophage

Forethine (mapiritsi) Kutalika: 28

Analogue ndiotsika mtengo kuchokera ku ma ruble 53.

Formetin ndimalo otsika mtengo kwambiri a Glucofage, omwe amapangidwa kuti achepetse shuga m'magazi. Amapezeka m'mapiritsi okhala ndi 0,5, 0,85 kapena 1 g wa metformin. Zitha kuyambitsa kusokonezeka kwa dongosolo la kugaya, zotupa pakhungu, komanso ngati mankhwala osokoneza bongo - hypoglycemia ndi lactic acidosis atha kufa.

Analogue ndiyotsika mtengo kuchokera 1 rub.

Glyformin imalowa m'malo mwa Glucofage yokhudzana ndi mankhwala omwe amasunganso kuchuluka kwa shuga m'magazi. Amamutsatira pakamwa poyambira 0,5 ga katatu patsiku pakudya kapena pambuyo pake. Mlingowo umakulitsidwa pang'onopang'ono mpaka 1 g pa mlingo uliwonse. Imagwiritsidwanso ntchito ngati othandizira mu kuchuluka kwa 0.1-0.2 g tsiku lililonse.

Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 68.

Metformin ndi mankhwala osokoneza bongo a hypoglycemic ofanana ndi Glucofage, chifukwa chotengera 500 mg piritsi limodzi. Amadziwikiranso pakukonzekera pakati, panthawi yoyembekezera komanso mkaka wa m'mawere, kuphwanya kwambiri chiwindi ndi / kapena impso. Munthawi yonse ya chithandizo, muyenera kupewa kumwa mowa wokhala ndi mankhwala a ethanol.

Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 161.

Siofor ndi njira ina yotsika mtengo yogwiritsira ntchito Glucophage, yogwira matenda a shuga 2, makamaka kwa odwala omwe ali ndi kunenepa kwambiri. Mankhwalawa angagwiritsidwe ntchito ngati monotherapy komanso kuphatikiza ndi insulin. Adalola kuikidwa kwa ana kuyambira azaka 10. Chenjezo limaperekedwa kwa okalamba omwe akugwira ntchito yolemetsa.

Glucophage 1000: malangizo ogwiritsira ntchito, mtengo, ndemanga, analogues

Glucophage ndi mankhwala omwe amachepetsa glucose wamagazi. Amapangidwa m'mapiritsi a pakamwa. Mankhwalawa akuwonetsedwa kwa anthu omwe ali ndi matenda a shuga a mtundu wachiwiri chifukwa cha kunenepa kwambiri.

Kugwiritsa

Glucophage ndi othandizira kutsitsa shuga pakuchita pakamwa (pakamwa), woimira biguanides. Zimaphatikizira gawo lomwe limagwira - metformin hydrochloride, ndi magnesium stearate ndi povidone amadziwikanso monga zinthu zowonjezera. Chigoba cha mapiritsi Glucofage 1000 chili, kuphatikiza hypromellose, macrogol.

Ngakhale kuchepa kwa shuga m'magazi, sikuti kumayambitsa hypoglycemia. Mfundo zoyeserera Glucophage zimakhazikika pakuwonjezera kuyanjana kwa insulin receptors, komanso pogwira komanso kuwononga glucose ndi maselo. Kuphatikiza apo, mankhwalawa amalepheretsa kupanga shuga m'magazi a chiwindi - poletsa njira za glucogenolysis ndi gluconeogenesis.

Chofunikira chachikulu pa mankhwalawa ndi kupanga glycogen ndi chiwindi. Zimaperekanso kuwonjezeka kwa kuchuluka kwa kayendedwe ka glucose kumaselo osiyanasiyana. Metformin ilinso ndi zotsatirapo zake - imatsitsa cholesterol ndi triglycerides, imathandizira kulowetsedwa kwamphamvu kwa glucose m'mimba.

Chimodzi mwamaubwino amwa mankhwalawa chifukwa cha matenda ashuga ndikuwtha kugwiritsa ntchito poonda. Glucofage imakuthandizani kuti musinthe kulemera kwa thupi motsutsana ndi kumbuyo kwa kunenepa kwambiri kapena kunenepa kwambiri m'njira yochepetsera, komanso kukhalanso ndi mawonekedwe abwinobwino poika mankhwala.

Malangizo ogwiritsira ntchito

Kukonzekera makonzedwe amkamwa mwa mawonekedwe a mapiritsi okhala ndi zokutira zoyera.

Kuyambira pachiyambi cha maphunzirowa, amawerengedwa kuchuluka kwa 500 kapena 850 mg kangapo patsiku panthawi yachakudya kapena mukatha kudya. Kudalira kuchuluka kwa magazi ndi shuga, mutha kuwonjezera pang'onopang'ono.

Gawo lothandizira panthawi ya chithandizo ndi 1500-2000 mg patsiku. Chiwerengero chonsecho chimagawidwa pamiyeso 2-3 kuti mupewe matenda osafunikira am'mimba. Mulingo woyenera kwambiri wokonza ndi 3000 mg, uyenera kugawidwa m'magawo atatu patsiku.

Kuti mulekerera bwino Glucofage wam'mimba, mutha kuwonjezera pang'onopang'ono mlingo, potero mulole thupi "kuzolowera" mankhwalawo.

Pakapita kanthawi, odwala amatha kusintha kuchokera ku mlingo wapadera wa 500-850 mg kukhala mlingo wa 1000 mg. Mlingo woyenera pazinthu zonsezi ali wofanana ndendende ndi kukonza mankhwalawa - 3000 mg, wogawidwa mu 3 waukulu.

Ngati kuli kofunika kusintha kuchokera ku gawo lomwe limatengedwa kale la hypoglycemic kupita ku Glucophage, muyenera kusiya kumwa koyambayo, ndikuyamba kumwa Glucophage pa mlingo womwe watchulidwa kale.

Kuphatikiza ndi insulin:

Sizimaletsa kuphatikiza kwa mahomoni awa ndipo sikuti zimayambitsa mavuto motsatizana. Itha kutengedwa palimodzi pazotsatira zabwino. Pachifukwa ichi, mlingo wa Glucofage uyenera kukhala wokhazikika - 500-850 mg, ndipo kuchuluka kwa insulini yoyendetsedwa kuyenera kusankhidwa poganizira kuchuluka kwa omwe ali m'magazi.

Ana ndi achinyamata:

Kuyambira zaka 10, mutha kudziwa mankhwala a glucophage onse amodzi mankhwala, komanso limodzi ndi insulin. Mlingo wofanana ndi akulu. Pakatha milungu iwiri, kusintha kwa mtundu wa glucose kumatha kuchitika.

Mlingo wa Glucophage mwa okalamba uyenera kusankhidwa poganizira momwe zida za impso zimakhalira. Kuti muchite izi, ndikofunikira kudziwa kuchuluka kwa creatinine mu seramu ya 2-4 kawiri pachaka.

Ndikofunikira kutenga Glucophage mosamalitsa malinga ndi malingaliro a dokotala komanso mlingo. Dokotala wokhayo yemwe amatha kusintha mlingo. Ngati wodwalayo asiya kumwa mankhwala a hypoglycemic, ayenera kuuzidwa dokotala mwachangu.

Mapiritsi oyera okhala ndi pakamwa. Ayenera kudyedwa kwathunthu, popanda kuphwanya umphumphu wawo, kutsukidwa ndi madzi.

Glucophage Kutalika 500 mg:

Kuwongolera mlingo wa 500 mg - kamodzi patsiku chakudya chamadzulo kapena kawiri pa 250 mg pa chakudya cham'mawa komanso chamadzulo. Kuchuluka kumeneku kumasankhidwa pa chizindikiritso cha shuga m'magazi am'magazi.

Ngati mukufuna kusintha kuchokera pa mapiritsi wamba kupita ku Glucofage Long, ndiye kuti muyezo womaliza umagwirizana ndi mlingo wa mankhwala wamba.

Malinga ndi kuchuluka kwa shuga, pakatha milungu iwiri amaloledwa kuonjezera mlingo woyambira ndi 500 mg, koma osapitilira muyeso waukulu - 2000 mg.

Ngati mphamvu ya mankhwala Glucofage Long yafupika, kapena sinafotokozeredwe, ndiye kuti ndikofunikira kumwa kwambiri monga momwe adanenera - mapiritsi awiri m'mawa ndi madzulo.

Kuchita ndi insulini sikusiyana ndi zomwe mumatenga glucophage osakhalitsa.

Imwani glucophage iyenera kukhala mosamalitsa malinga ndi malangizo. Ngati cholowera chimodzi chidasowa (m'mawa), mlingo watsopano umakhala woledzera patsiku lotsatira (madzulo).

Glucophage Long 850 mg:

Mlingo woyamba wa Glucophage Long 850 mg - piritsi 1 patsiku. Mlingo waukulu kwambiri ndi 2250 mg. Kulandila ndikufanana ndi mlingo wa 500 mg.

Malangizo a Glucofage 1000 ogwiritsa ntchito:

Mlingo wa 1000 mg ndi wofanana ndi njira zina zazitali - piritsi limodzi patsiku ndi chakudya.

Contraindication

Simungathe kumwa mankhwalawa kwa anthu omwe akudwala:

• ketoacidosis motsutsana ndi matenda a shuga
• kuyambira kuphwanya ntchito ya aimpso zida ndi chilolezo zosakwana 60 ml / min
• kusowa kwamadzi chifukwa cha kusanza kapena kutsegula m'mimba, kugwedezeka, matenda opatsirana
• matenda a mtima monga kulephera kwa mtima
• matenda a m'mapapo - CLL
• Kulephera kwa chiwindi ndi kuwonongeka kwa chiwindi
• uchidakwa wosatha
• tsankho la munthu mankhwala

Kuphatikiza apo, ndizoletsedwa kutenga Glucofage kwa amayi apakati omwe amatsata zakudya zama calorie otsika, kwa anthu omwe ali pachiwopsezo kapena chikomokere motsutsana ndi maziko a matenda ashuga.

Mapiritsi oyera, okhala ndi mapiritsi a 500, 850 ndi 100 mg. Kugwiritsa ntchito mankhwalawa - pakudya, ndi madzi. Mlingo amawerengedwa payekhapayekha kwa wodwala aliyense, poganizira momwe amawonetsa glucose komanso kuchuluka kwa kunenepa kwambiri, chifukwa mankhwalawo ndi oyeneranso kuchepetsa thupi.

Zotsatira zoyipa

Zotsatira zoyipa mthupi zimatha kuchitika - monga:

• dyspepsia - chikuwonetsedwa ndi mseru, kusanza, kutsegula m'mimba, kupweteka kwam'mimba, kugona mosakhalitsa (kuchuluka kwa mpweya)
• mavuto amakomedwe
• kuchepa kwamtima
• chiwindi chiwindi - kuchepa kwa ntchito ya ntchito zake mpaka kukula kwa chiwindi mbali ya pakhungu - zotupa oyenda, erythema
• kutsika kwa vitamini B12 - motsutsana ndi maziko a kumwa kwa nthawi yayitali

Mtengo umasiyanasiyana malo ogulitsa ogulitsa ndi malo ogulitsira pa intaneti. Mtengo umatengera mlingo wa mankhwalawo komanso kuchuluka kwa mapiritsi omwe ali phukusi.

Mu malo ogulitsira pa intaneti, mafotokozedwe amitengo yamathumba a mapiritsi ochulukirapo 30 - 500 mg - pafupifupi ma ruble 130, 850 mg - 130-140 rubles, 1000 mg - pafupifupi ruble 200.

Mlingo womwewo, koma kwa paketi yokhala ndi zidutswa 60 phukusi - 170, 220 ndi 320 ma ruble, motsatana.

M'maketi ogulitsa mankhwala, mtengo wake umatha kukhala wokwera pamitundu yokwana 20-30 rubles.

Chifukwa cha mankhwala omwe amagwiritsidwa ntchito a metformin, Glucofage ili ndi mitundu yambiri. Nawa ochepa mwa iwo:

• Siofor. Mankhwala omwe ali ndi mfundo zomwezi. Ndi njira yotetezeka kwambiri ya mankhwala a hypoglycemic yochepetsa thupi. Kuphatikiza apo, mavuto osowa kwambiri adadziwika. Mtengo pafupifupi ndi 400 rubles.
• Nova Met. Chodabwitsa cha mankhwalawa ndikuti kugwiritsa ntchito kwake kwa anthu omwe ali ndi zaka zocheperako komanso kwa anthu ogwira ntchito zolimba. Chowonadi ndi chakuti, Nova Met amatha kupangitsa kuti mawonekedwe a lactic acidosis asinthe. Kuphatikiza apo, anthu okalamba amatha kudwala matenda a impso chifukwa cha zizindikiro zomwe zikusowa. Mtengo wake ndi pafupifupi ma ruble 300.
• Metformin. M'malo mwake, ichi ndiye chinthu chonse cha zochitika zonse za Glucofage ndi iye. Ili ndi katundu yemweyo. Mtengo muma pharmacies pafupifupi 80-100 rubles.

Bongo

Monga tafotokozera pamwambapa, mankhwalawa samathandizira hypoglycemia - komanso ndi bongo wambiri. Koma zikavuta pakachulukidwe kovomerezeka, kotchedwa lactic acidosis imayamba. Izi ndizachidziwikire, koma zowopsa, chifukwa zimatha kufa.

Ngati bongo wa Glucofage, ndikofunikira kusiya kumwa mankhwalawa. Kugonekedwa kuchipatala msanga, kuyezetsa kuchipatala ndi kuzindikira kwawonetsedwa. Syndromealili amasonyezedwa, koma hemodialysis ndiye njira yabwino koposa.

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Ngakhale kuti wodwalayo achepa, kulemera kwake kunakhalabe pamanambala am'mbuyomu - kupatula kuti anasintha mkati mwa ma kilogalamu 1-2 - Adriana Glyukofzh samalimbikitsa kuwonda.

Dora adalemba ndemanga pa HTER: adzakhala ndi chidwi ndi mankhwalawa.

Tasha akupereka ndemanga zabwino http://otzovik.com/review_2258774.html Kuchepa kwa glucose kumawonekera, koma hypoglycemia sikuwoneka. Wodwalayo adanenanso kuchepa kwa chikondwerero, ndikufotokozera mwatsatanetsatane njira yothira mankhwalawa pa mlingo wa 1000 mg.

Irina patsambalo http://www.stroineemvmeste.ru/blog/glyukofazh-dlya-pox motlya/5183 imapereka chiwonetsero chovuta kwambiri cha mankhwalawa. Ndemanga zoterezi zimachitika chifukwa chakuti dotolo adakhazikitsa mankhwala ochepetsa thupi - komabe, mavuto obwera chifukwa cha dyspepsia - makamaka, kutsegula m'mimba ndi kusabereka kunampangitsa kuti ayimitse mankhwala.

Marina akuti http://pohudejkina.ru/glyukofazh-dlya-pohudeniya.html#otzyvy-vrachey-i-specialistov/ kuti mankhwalawa Glyukofazh 1000 adamuthandiza kuti achepetse thupi pambuyo pobereka - ndipo alibe matenda a shuga. Pamodzi ndi zolimbitsa thupi, mankhwalawa adamuthandiza kuti achepetse kulemera kwake.

Elena pobwereza http://mirime.ru/diet-tablets/glucophage.html akuti zotsatira zoyipa zimamuvutitsa iye atangoyamba kumene maphunziro a Glucofage, komanso motsutsana ndi magwiritsidwe ntchito a zotsekemera za ufa, ndipo kuchepa thupi kumachitika motsutsana ndi magwiritsidwe ntchito a nthawi yayitali.

Pomaliza

Glukonazh 1000 ndi mankhwala abwino kwambiri kwa anthu odwala matenda ashuga. Sizothandiza kungoyendetsa kuchuluka kwa shuga, komanso zimachepetsa thupi, motero zithandizanso anthu omwe akufuna kuchepa thupi. Komabe, simuyenera kuigwiritsa ntchito mosaganizira - muyenera kuyitenga monga mwauzidwa ndi dokotala. Musanagule mankhwalawa, funsani katswiri.

Sungani kapena gawani:

Glucophage Long Slimming - malangizo angagwiritsidwe ntchito mankhwala, analogi ndi mtengo

Matenda a metabolism ndi mtundu wamba wa matenda omwe amayambitsa mavuto akulu azaumoyo: matenda a shuga, kunenepa kwambiri. Pa mtima pa matenda onsewa ndi kusakhazikika kwa minyewa kupita ku insulin. Kuti muthane naye, pali mankhwala omwe amachiza matenda ndikuchotsa mapaundi owonjezera.

Makampani ogulitsa mankhwala amapereka njira yothetsera kunenepa kwambiri ndi matenda a shuga a Glucophage Long. Gulu la pharmacological ndi othandizira odwala matenda ashuga. Kutulutsa Fomu - makapisozi oyera.

Chofunikira chachikulu ndi metformin hydrochloride. Mlingo wake umatha kusiyana 500 mpaka 750 mg.

Malangizo a Glucophage Long akuti zachitika nthawi yayitali, kotero kuti mapiritsi satengedwa mobwerezabwereza 1-2 kugogoda.

Mankhwalawa amatengedwa pamene msinkhu wa shuga ukufunika kutsitsidwa. Mu thupi lathanzi, izi zimachitika mwachilengedwe. Kulephera kumachitika pamene timadzi tating'onoting'ono tomwe timayambitsa matenda a glucose sadziwika ndi minofu. Zisonyezero zogwiritsa ntchito glucophage yayitali ndi motere:

• kunenepa kwambiri
• shuga kwa akulu,
• ubwana ndi matenda a shuga achinyamata
• chitetezo chokwanira mthupi la insulin.

Contraindication yogwiritsira ntchito ndi mimba chifukwa choopseza kubadwa kwa maliseche mwa mwana, ngakhale palibe chidziwitso chokwanira chonena izi motsimikiza.

Mimba ikachitika munthawi ya mankhwalawa, mankhwalawo amayenera kuthetsedwa ndipo njira zamankhwala zimasinthidwa. Palinso deta yokwanira pa zomwe zimachitika pa ana poyamwitsa.

Komabe, zimadziwika kuti gawo lalikulu limadutsa mkaka wa m'mawere, kotero kugwiritsa ntchito mankhwalawa panthawi yotsekemera sikulimbikitsidwanso. Kapangidwe kake sikogwirizana ndi mowa.

Malo ena ogwiritsira ntchito mankhwalawa ndikusintha thupi.

Glucophage kutalika kwa kuchepa kwa thupi kumayikidwa chifukwa kumachepetsa kuchuluka kwa shuga, kumalimbikitsa kuyamwa kwake, ndiye kuti, kumawongolera mamolekyulu a shuga m'matumbo.

Momwe, mothandizidwa ndi kulimbitsa thupi, shuga amamwetsedwa ndipo ma acid acid amakhathamiritsidwa, kuyamwa kwa michere kumachepetsa. Zonsezi zimakhudza chilakolako cha kudya, chomwe chimachepetsedwa kwambiri, zomwe zimapangitsa kuti muchepetse kunenepa.

Glucophage Mtengo Wautali

Mtengo wa mankhwalawa m'mafakisi ku Moscow ndi dera la Moscow umachokera ku 280 mpaka 650 rubles. Mtengo wa Glucophage Long zimatengera kapangidwe kazinthu zomwe zimagwira. Phukusi la mapiritsi 30 achi French ophatikizidwa ndi kipimo cha 500 mg metformin imatengera 281 p., Norway - 330 p.

Phukusi la zidutswa 60 lingagulidwe pamtengo wa 444 ndi 494 p. Mapiritsi 30 Glucofage 750 Kutalika komwe amapangidwa ku France atenga 343 rubles, Norway - 395 rubles. Mapaketi a mapiritsi 60 amatenga ma ruble 575 ndi 651, kutengera dziko lopanga.

Pamtengo wabwinoko, chidacho chitha kuyitanitsidwa kuchokera pa zikwangwani pa intaneti.

Analogs a mankhwala Glucofage

Metformin
Sindikizani mndandanda wazofanana
Metformin (Metformin) Hypoglycemic wothandizila kukonzekera pakamwa pa gulu la zigubu zam'magulu akulu, mapiritsi

Biguanide, othandizira pakamwa.

Odwala omwe ali ndi matenda a shuga, amachepetsa kuchuluka kwa shuga m'magazi poletsa gluconeogenesis m'chiwindi, kuchepetsa kuchepa kwa glucose m'matumbo am'mimba ndikuwonjezera kugwiritsidwa ntchito kwake mu minofu, Kumachepetsa kuchuluka kwa TG, cholesterol ndi LDL (kutsimikizika pamimba yopanda kanthu) mu seramu yamagazi. Imakhazikika kapena kuchepetsa thupi.

Pakakhala insulin m'magazi, chithandizo cha mankhwala sichikuwonetsedwa. Hypoglycemic zimachitika sizimayambitsa. Amawongolera michere yamagazi ya fibrinolytic chifukwa cha kuponderezedwa kwa choletsa wa activator profibrinolysin (plasminogen).

Type 2 shuga mellitus mwa akulu (kuphatikiza gulu la sulfonylurea kukhala losagwira), makamaka pazokhudza kunenepa kwambiri.

Zotsatira zoyipa

Kuchokera pamimba: kukhumudwa, kusanza, "zitsulo" mkamwa, kuchepa kwa chilakolako chofuna kudya, kukomoka, kupweteka kwam'mimba.

Kuchokera kumbali ya kagayidwe: nthawi zina - lactic acidosis (kufooka, myalgia, kupuma, kugona, kupweteka kwam'mimba, hypothermia, kuchepa kwa magazi, Reflex bradyarrhythmia), ndi chithandizo cha nthawi yayitali - hypovitaminosis B12 (malabsorption).

Kuchokera ku ziwalo za hemopoietic: Nthawi zina - megaloblastic anemia.

Thupi lawo siligwirizana: zotupa pakhungu.

Pazifukwa zoyipa, mankhwalawa amayenera kuchepetsedwa kapena kuletsedwa kwakanthawi.

Zomwe mungasankhe shuga: Siofor kapena Glucofage

Siofor ili ndi chinthu chimodzi chomwe chimagwira. Ndiye chifukwa chake mankhwalawa ndi ofanana kwambiri. Madokotala ena amakhulupirira kuti glucophage ndiyotetezeka, chifukwa zimakhala ndi mankhwala ochepa othandizira. Koma maphunziro omwe angatsimikizire kapena kutsutsa izi sanachitikebe pakadali pano.

Imakhala ndi chithandizo chambiri kwa nthawi yayitali ndipo samayambitsa kusintha kwadzidzidzi m'thupi la magazi. Komanso, chinthu chofunikira chomwe chingakhudze kusankha kwa mankhwalawa ndikuti Glucofage ndi dongosolo la kukula kotsika mtengo kuposa Siofor.

Zomwe mungasankhe mukamachepetsa thupi: Siofor kapena Glyukofazh

Kutengera kuti metformin ndiyo gawo lalikulu la mankhwala onsewa, zingakhale zolondola kunena kuti zimathandizanso kagayidwe kenakake ndikuthandizira kuwotcha mafuta owonjezera thupi.

Komabe, ndikofunikira kudziwa kuti munthu aliyense amakhala ndi chidwi chomva mankhwala, motero amathandiza Glucophage bwino, pomwe ena akumva mphamvu ya Siofor. Koma odwala ambiri omwe adagwiritsa ntchito zinthu zonse ziwiri zolemetsa izi amati sazindikira kusiyana pakati pawo. Tiyenera kudziwa kuti kuwonjezera pa kumwa mankhwalawa, umafunikanso kusintha moyo wako kuti zotsatira zake zikhale zofunikira kwambiri.

Glucovans monga analogue

Kusiyanitsa kwakukulu pakati pa mankhwala awiriwa ndikuti Glucovans amatanthauza mankhwala osakanikirana, omwe ndi omwe amakhala ndi zosakaniza zingapo nthawi imodzi. Zigawozi (glibenclamide ndi metformin) ndi zamagulu osiyanasiyana a mankhwala a antipyretic.

Glibenclamide ndi woimira m'badwo wachiwiri wa zotumphukira za sulfanylurea, ndipo Metformin ndi biguanides. Glucovans imatchedwa chida chothandiza kwambiri pochiza matenda ashuga, chifukwa imakwaniritsa zotsatira zake zochizira nthawi yomweyo pogwiritsa ntchito njira zingapo zoyambira. Glucophage amalimbikitsidwa kwa odwala omwe ali ndi zovuta zodwala.

Zomwe zili bwino kusankha kwa odwala matenda ashuga: Metmorfin kapena Glucofage

Mankhwala onse awiriwa ali ndi zigawo zazikuluzikulu, zomwe zimapereka kufanana kwambiri pakati pa mankhwalawa. Mwayi wachiwiri ukhoza kutchedwa kuti imapezekanso m'njira zowonjezera. Chifukwa chake, mankhwalawa amatha kumwa kamodzi patsiku. Izi zitha kuonjezera kutsatira kwa wodwala chithandizo.

Ngakhale madokotala sangavomerezane pazomwe zimagwira ntchito kwambiri: Glucofage kapena Metformin, popeza kusiyana pakati pawo ndikosakwanira. Chifukwa chake, muyenera kuyang'ana pazomwe wodwala aliyense amapeza mankhwalawa.

Metmorphine kapena Glucophage: ndibwino kuti muchepetse kunenepa

Mankhwala onsewa amathanso kuperekedwa kwa odwala omwe amafunikira kuwongolera kuchipatala. Mankhwalawa onse amatenga kagayidwe kazakudya:

• kuchuluka kwa shuga ndi minofu,
• kuchepa kwa ndende yake m'magazi.

Komanso, mankhwalawa amateteza kagayidwe ka mafuta, amachepetsa kuchuluka kwa lipoprotein m'madzi a m'magazi, omwe ali ndi mphamvu ya atherogenic m'mitsempha yamagazi. Kuphatikiza apo, mankhwalawa onse amakhudza kumverera kwa njala, amachepetsa mphamvu ndikuchepetsa chilako cha chakudya.

Pofuna kuti njira yochepetsera thupi ikhale yothamanga komanso yothandiza kwambiri, kuphatikiza kumwa mapiritsi ndi kuwonjezeka kwa zolimbitsa thupi (zolimbitsa thupi, kulimbitsa thupi, kulimbitsa thupi) komanso kuphatikiza chakudya (kuphatikizapo michere yambiri, masamba atsopano, zipatso ndi zipatso m'malo mwabwino).

Glformin ndi Glucofage: kufotokozera kofananira

Mankhwala onse awiriwa ali m'gulu la mapiritsi amkamwa okhala ndi vuto la hypoglycemic. Zomwe zimapangidwa zimakhala zofanana, ndipo kusiyanasiyana kumangokhala pazinthu zosiyanasiyana zamankhwala othandizira. Madokotala amawona kuti mankhwalawa amagwiranso ntchito moyenera pochiza anthu omwe ali ndi matenda a shuga omwe amadalira insulin komanso kunenepa kwambiri.

Odwala omwe amatenga mankhwalawa nthawi zambiri sanazindikire kusiyana kulikonse pakati pawo. Komabe, panali milandu yolekerera imodzi ya mankhwalawa, koma izi zimatengera kale mawonekedwe amthupi la wodwalayo.

Diabetes ngati wogwirizira

Diabetes ndi m'gulu la amachokera ku sulfanylurea ndipo amazindikira zotulukapo zake chifukwa cha kukoka kwa kupanga kwa insulin chifukwa cha maselo a pancreatic islet. Diabetes imatha kuchepetsa kuchuluka kwa shuga m'magazi am'magazi, koma sizimakhudza kulemera kwa wodwalayo. Ndiye kuti, odwala omwe ali ndi kunenepa kwambiri sizikupanga nzeru kutenga matenda a shuga.

Mukamagwiritsa ntchito formin ngati analogue

Formformin ilinso ndi Metformin momwe imapangidwira, motero zotsatira za mankhwalawa ndizofanana kwambiri. Fomu imatha kuphatikizidwanso kwa odwala omwe ali ndi mafuta ochulukirapo a subcutaneous ndi visceral mafuta. Mankhwalawa onse amadziwika kuti ndi othandiza komanso otetezeka.

Mndandanda wazofananira zina

Kuphatikiza pa mankhwala omwe ali pamwambawa, mankhwala omwe ali m'munsiwa atha kusintha:

• Reduxin Met.
• Bagomet.
• Metformin-Teva.
• Glycidone.
• Gliclazide.
• Acarbose.
• Glucobay.

Mukamayandikira mankhwala osokoneza bongo mosamala komanso mosamala, ndiye kuti nthawi zambiri pamakhala zovuta zina.

Malangizo apadera

Pa mankhwala, kuwunika aimpso ndikofunikira; kutsimikiza kwa plasma lactate kuyenera kuchitika kawiri pachaka, komanso maonekedwe a myalgia. Ndi chitukuko cha lactic acidosis, kusiya kwa mankhwala kumafunika.

Kukhazikitsidwa sikulimbikitsidwa chifukwa cha matenda oopsa, kuvulala, ndi chiopsezo chofuna madzi m'thupi.

Ndi mankhwala ophatikizika a sulfonylurea, kuyang'anitsitsa shuga wamagazi ndikofunikira.

Ntchito zophatikizidwa ndi insulin tikulimbikitsidwa kuchipatala.

Kuchita

Amachepetsa Cmax ndi T1 / 2 ya furosemide ndi 31 ndi 42.3%, motsatana.

Zosagwirizana ndi ethanol (lactic acidosis).

Gwiritsani ntchito mosamala limodzi ndi anticoagulants osalunjika komanso cimetidine.

Zotsatira za sulfonylureas, insulin, acarbose, MAO zoletsa, oxytetracycline, ACE zoletsa, clofibrate, cyclophosphamide ndi salicylates zimathandizira.

Pogwiritsa ntchito munthawi yomweyo ndi GCS, njira yolerera yoletsa kukonzekera pakamwa, epinephrine, glucagon, mahomoni a chithokomiro, zotengera za phenothiazine, zotupa za thiazide, zotumphukira za nicotinic acid, kuchepa kwa mphamvu ya hypoglycemic ya metformin ndikotheka.

Furosemide imachulukitsa Cmax ndi 22%.

Nifedipine imawonjezera mayamwidwe, Cmax, imachepetsa mayeso.

Mankhwala a Cationic (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren ndi vancomycin) omwe amatulutsidwa m'mapikisano olimbana ndi machitidwe ogwiritsira ntchito ma tubular ndipo amatha kuonjezera Cmax ndi 60% ndi chithandizo chanthawi yayitali.

Kutulutsa mawonekedwe ndi kapangidwe kake

Mapiritsi a Glucophage ali ndi mawonekedwe ozungulira (Mlingo wa 1000 mg - chowulungika), mawonekedwe a biconvex ndi mtundu woyera. Chofunikira chachikulu ndi metformin hydrochloride. Pali 3 Mlingo wa mankhwala, zomwe zili ndi yogwira - 500 mg, 850 mg ndi 1000 mg piritsi limodzi. Komanso, kapangidwe kake ka mankhwalawa amaphatikizanso zinthu zina zothandiza, monga:

• Hypromellose.
• Povidone K30.
• Magnesium wakuba.

Mapiritsi a Glucophage amadzaza matuza a 10 ndi 20 zidutswa. Phukusi la makatoni mumakhala mapiritsi osiyanasiyana - 30, 60. Mulinso malangizo ogwiritsira ntchito mankhwalawa.

Zotsatira za pharmacological

Chofunikira chachikulu cha mapiritsi Glucofage metformin mu kapangidwe ka mankhwala chimatanthauzira kuti biguanides. Kuchepetsa kwake shuga kumachitika kudzera munjira izi:

• Kuchulukitsa chidwi cha ma cell receptors ku insulin, potero kumawonjezera kuyamwa kwa glucose.
• Imachepetsa njira ya gluconeogenesis (kaphatikizidwe kagayidwe) ka hepatocytes (ma cell a chiwindi).
• Iachedwetsa kuyamwa kwa chakudya kuchokera ku lumen yaing'ono.
• Imakongoletsa mawonekedwe a lipid a metabolism, monga, amachepetsa cholesterol, triglycerides ndi otsika kachulukidwe lipoproteins (LDL) m'magazi.

Metformin siyimakhudzanso kuchuluka kwa insulin yotchinga maselo a kanyumba kamene kamayambitsa ma kapamba, motero sikumabweretsa hypoglycemia (kuchepa kwakukulu kwa shuga m'magazi m'munsi mwabwinobwino).

Mutatenga piritsi la Glucophage, chinthu chogwira chimatengedwa mu kayendedwe ka magazi kuchokera ku lumen yaying'ono. Zake bioavailability ndi 50-60%, amachepetsa pamene akumwa mankhwalawo ndi chakudya.

Kuchuluka kwa metformin m'magazi kumafikira maola 2.5 mutamwa mapiritsi. Chidacho chophatikizika chimaphatikizidwa m'chiwindi, zomwe zimapangitsa kuti ziwunduke komanso metformin pazokha zimapukusidwa makamaka ndi impso m'njira yosasinthika.

Hafu ya moyo (nthawi yomwe theka lathunthu la mankhwalawa limachotsedwa m'thupi) ndi maola 6.5.

Mlingo ndi makonzedwe

Mapiritsi a Glucophage amatengedwa pakamwa pakudya kapena pambuyo pake. Mutatha kumwa mapiritsi, muyenera kumwa ndi madzi okwanira. Mlingo wa mankhwalawa zimatengera kuchuluka kwa kuchuluka kwa shuga wamagazi ndi kugwiritsa ntchito mankhwala ena ochepetsa shuga:

• Nthawi zambiri, muyeso woyamba wa mapiritsi a glucophage ndi 500-850 mg mu 2-3. M'tsogolomu, mutayendetsa kuchuluka kwa shuga m'magazi, mlingowo ungawonjezeke.
• Pulogalamu yatsiku ndi tsiku yokonza ndi 1500-2000 mg, iyenera kugawidwa m'magawo atatu kuti mukwaniritse bwino bioavailability ndikuchepetsa zovuta zoyambira m'mimba.
• Mulingo wovomerezeka woyenera ndi 3000 mg wa patsiku, wogawidwa pawiri.
• Ngati ndi kotheka, onjezani mlingo, kuchuluka kwa mankhwalawa kumawonjezeka pang'onopang'ono, kuti muchepetse chiopsezo cha mavuto.
• Ndi kuphatikiza kwa mapiritsi a glucophage ndi insulin, mlingo woyambirira wa mankhwalawa ndi 500-850 mg katatu patsiku. Mulingo wa shuga wamagazi umakonzedwanso ndikusintha mlingo wa insulin.
• Kwa ana opitirira zaka 10, mankhwalawa amatha kugwiritsidwa ntchito ngati monotherapy kapena kuphatikiza ndi insulin, mlingo wamba ndi 500-850 mg kamodzi patsiku. M'tsogolo, zitha kuchuluka. Mlingo wambiri watsiku ndi tsiku ndi 2000 mg.
• Kwa anthu achikulire, mapiritsi a Glucophage amasankhidwa malinga ndi zomwe zikuchitika mu impso.

Kutalika kwa kugwiritsa ntchito mapiritsi a Glucophage amakhazikitsidwa payekhapayekha. Ayenera kutengedwa tsiku lililonse. Ngati mukuphonya piritsi, muyenera kuwona dokotala, monga kusintha kwa mankhwalawa kungafunikire.

Mtengo wamagetsi

Mtengo wapakati wa mapiritsi a Glucophage ku malo ogulitsa mankhwala ku Moscow zimatengera kuchuluka kwawo komanso kuchuluka kwa ntchito yayikulu:

• 500 mg, mapiritsi 30 - 113-127 rubles.
• 500 mg, mapiritsi a 60 - ma ruble a 170-178.
• 850 mg, mapiritsi 30 - ma ruble 119-125.
• 850 mg, mapiritsi 60 - 217-233 rubles.
• 1000 mg, mapiritsi 30 - ma ruble 186-197.
• 1000 mg, mapiritsi 60 - 310-334 rubles.