Udindo wa glucophage pachatgenetic chithandizo cha matenda a shuga a 2
Wolemba mu magazine:
Cancer Cancer Vol 18, No. 10, 2010
Ph.D. I.V. Kononenko, pulofesa O.M. Smirnova
Federal State Institution Endocrinological Research Center, Moscow
Type 2 matenda a shuga ndi matenda osachiritsika omwe amakhala ndi hyperglycemia, omwe amayamba chifukwa cha zolakwika zobisika komanso zochita za insulin. Ichi ndi matenda oopsa, osachiritsika komanso opita patsogolo. Zotsatira zabwino za odwala omwe ali ndi matenda a shuga 2 mtundu wa 2 amatsimikizika ndi kukula kwa zovuta zazikulu komanso zazikulu. Zomwe zimayambitsa zovuta zazikulu ndi ma cell opatsirana a atherosulinotic of the arterial pools, zomwe zimatsogolera pakupanga matenda a mtima ndi zovuta zake, matenda amitsempha yamagazi komanso zotupa za m'mitsempha yam'munsi. Maziko a zovuta zavasvasvas ndizowonongeka kwakanthawi kwamasamba, makamaka kwa matenda ashuga, omwe amalumikizidwa ndi makulidwe am'munsi mwa capillaries. Mawonetsedwe azachipatala a microangiopathy ndi matenda a shuga ndi nephropathy. DM ndiyomwe imapangitsa kwambiri khungu kwa akuluakulu. Cholinga cha chithandizo cha matenda ashuga ndikusinthasintha glycemia ndikuchepetsa chiopsezo cha zovuta zazikulu za macro- ndi microvascular. Zofunikira kwambiri zowopsa zomwe zimakhudza kukula kwa mtima wamankhwala kwa odwala omwe ali ndi matenda a shuga a 2 ndi mtundu wa metabolism ya carbohydrate, kuthamanga kwa magazi ndi kuchuluka kwa madzi a lipid. Gome 1 ikuwonetsa zofunikira pazisonyezo zazikulu, kukwaniritsa kwake komwe kumatsimikizira kuyenera kwa chithandizo cha odwala omwe ali ndi matenda a shuga a 2.
Tebulo 1. Kuwongolera magawo (njira zakuchiritsira) zamtundu wa 2 wa matenda a shuga (Algorithms posamalira mwapadera odwala omwe ali ndi matenda a shuga mellitus, 2009)
