Levemir - malangizo ntchito

"Levemir" ndi mankhwala ochiritsira omwe amagwiritsidwa ntchito mogwirizana ndi malangizo omwe angagwiritsidwe ntchito kuteteza matenda a insulin, mosasamala kuchuluka kwa chakudya chomwe chatengedwa komanso zakudya zomwe mumadya. Madokotala nthawi zambiri amalimbikitsa njira yothetsera vutoli kwa odwala awo kuti achepetse shuga. Zomwe zimagwira mu kapangidwe kake ka mankhwala ndi katundu ndizofanana ndi insulin, yomwe imapangidwa m'thupi la munthu.

Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD

Mankhwala ndi madzi owonekera bwino mu cholembera ndi chosakanizira. Ndi m'gulu la othandizira a hypoglycemic. Kuyika maphukusi kumakupatsani mwayi wowonjezera insulini mulingo uliwonse - kuchokera pa 1 unit mpaka 60. Kusintha kwa Mlingo ndikotheka kwa gawo. Kusintha kwina kwa dzinalo kungatchulidwe pa phukusi la mankhwalawa: LEVEMIR FlexPen kapena LEVEMIR Penfill.

Gawo lalikulu ndi insulin.

Zowonjezera:

  • glycerol
  • sodium kolorayidi
  • metacresol
  • phenol
  • hydrochloric acid
  • zinc acetate
  • hydrogen phosphate dihydrate,
  • madzi.

Kuyika katundu ndi koyera. Mkati mwa LEVEMIR Penfill ndi makatoni amgalasi okhala ndi 3 ml of solution (300 ED) iliyonse. Chigawo chimodzi chili ndi 0,142 mg yogwira ntchito. LEVEMIR FlexPen imayikidwa mu cholembera.

Zofunika! Mankhwala akapaka cartridge akapera, cholembera uyenera kutayidwa!

Opanga INN

Opangawo ndi Novo Nordisk, Denmark. Dzinalo losavomerezeka "ndi insulin."

Kukonzekera kumapangidwa ndi njira yachilengedwe yochokera pa chinthu chopangidwa ndi DNA chogwiritsa ntchito gawo la Saccharomyces cerevisiae.

Mtengo wogulitsa wa mankhwalawa umasiyanasiyana 1300 mpaka 3000 rubles. "FlexPen" imawononga ndalama zochepa kuposa "PenFill", chifukwa ndizosavuta kugwiritsa ntchito.

Pharmacology

Levemir ndi analogue yochita kupanga ya insulin kwa nthawi yayitali. Pamalo opangira jakisoni, pamakhala odziyimira okha a mamolekyulamu a insulin komanso kuphatikiza kwawo ndi albumin, chifukwa chinthucho chimagwira pang'onopang'ono m'matupi a chandamale ndipo sichilowa nthawi yomweyo m'magazi. Pali magawidwe pang'onopang'ono ndikuyamwa kwa mankhwalawa.

Kuphatikiza kwama mamolekyulu ndi mapuloteni kumachitika m'mbali mwa mbali yamafuta am'kati mwa asidi.

Makina oterewa amakhala ndi kuphatikiza komwe kumapangitsa kuti mayendedwe a chithokomiro chithandizidwe ndikuthandizira kayendedwe ka metabolic.

Pharmacokinetics

Pazipita voliyumu imadziwikiridwa ndi plasma maola 6-8 mutatha kubayidwa. A ndende yofanana ndi iyo pawiri mlingo zimatheka 2 kapena 3 jakisoni. Mankhwalawa amagawidwa m'magazi mu muyeso wa 0,1 l / kg. Chizindikirochi chimatheka chifukwa chakuti chinthucho sichimangiriza mapuloteni, koma chimadziunjikira ndikuzungulira mu plasma. Pambuyo pakulephera, zinthu za metabolic zimachotsedwa m'thupi pambuyo pa maola 5-7.

Mankhwala amapatsidwa shuga wambiri. Ankakonda kuchitira achikulire ndi ana kuyambira zaka ziwiri.

Kumayambiriro kwa mankhwala a insulin, Levemir imayendetsedwa kamodzi, yomwe imathandizira kuyendetsa bwino glycemia.

Mankhwalawa amachepetsa kwambiri chiopsezo cha hypoglycemia usiku.

Kupeza mlingo woyenera kuti muthe kusintha matenda sizovuta. Kuchiza ndi Levemir sikuti kumabweretsa kulemera.

Nthawi yomwe mankhwalawa amathandizidwa amatha kusankhidwa pawokha. M'tsogolomu, sikulimbikitsidwa kuti musinthe.

Malangizo ogwiritsira ntchito (mlingo)

Kutalika kwa mankhwalawa kumatengera mlingo. Kumayambiriro kwa mankhwalawa kuyenera kunenedwa kamodzi patsiku, makamaka tsiku lomaliza chakudya chamadzulo kapena musanagone.Kwa odwala omwe sanalandire insulin m'mbuyomu, Mlingo woyambirira ndi magawo 10 kapena magawo 0,1-0.2 pa kilogalamu ya thupi.

Kwa odwala omwe akhala akugwiritsa ntchito hypoglycemic kwa nthawi yayitali, madokotala amalimbikitsa kuchuluka kwa pafupifupi 0,4,4 magawo a kilogalamu iliyonse ya thupi. Kuchitikaku kumayambira pambuyo pa maola 3-4, nthawi zina mpaka maola 14.

Mlingo woyambira nthawi zambiri umaperekedwa nthawi 1-2. Mutha kulowa yomweyo kamodzi kapena kugawa kawiri. Pachiwiri, mankhwalawa amagwiritsidwa ntchito m'mawa komanso madzulo, nthawi yolumikizirana imayenera kukhala maola 12. Mukasintha kuchokera ku mtundu wina wa insulin kupita ku Levemir, mlingo wa mankhwalawa sungasinthe.

Mlingo wawerengedwa ndi endocrinologist potengera izi:

  • kuchuluka kwa zochitika
  • zopatsa thanzi
  • shuga
  • kuopsa kwa matenda,
  • zochitika tsiku ndi tsiku
  • kukhalapo kwa matenda oyanjana.

Mankhwalawa amatha kusinthidwa ngati pakufunika opaleshoni.

Zotsatira zoyipa

Pafupifupi 10% ya odwala amafunsira limodzi matendawa. Mu theka la milandu, iyi ndi hypoglycemia. Zotsatira zina pambuyo pa makonzedwe zimawonetsedwa ngati kutupa, redness, kupweteka, kuyabwa, kutupa. Kuwonongeka kumatha kuchitika. Zotsatira zoyipa zimatha patatha milungu ingapo.

Nthawi zina vutoli limakulirakulira chifukwa cha kuchuluka kwa matenda ashuga, zimachitika mwanjira inayake: matenda a shuga. Cholinga cha izi ndikusunga kuchuluka kwa glucose komanso kupewa glycemia. Thupi limapangidwanso, ndipo likasinthana ndi mankhwalawo, Zizindikiro zimapita zokha.

Mwa zina zoyipa zomwe zimachitika, zomwe ambiri ndi:

  • Kulakwitsa kwa chapakati mantha dongosolo (kuchuluka kumva kupweteka, kumva mphamvu za malekezero, kusokonekera kwamphamvu kuona ndi kuona kopepuka, kumva kugunda kapena kugunda kwamphamvu)
  • zovuta zamagulu kagayidwe kazakudya (hypoglycemia),
  • urticaria, kuyabwa, ziwengo, mantha anaphylactic,
  • zotumphukira edema
  • matenda a adipose minofu, zomwe zimatsogolera kusintha kwa mawonekedwe amthupi.

Onsewa amaphunzitsidwa pogwiritsa ntchito mankhwala osokoneza bongo. Ngati izi sizikuthandizani, dokotala amadzatenga mankhwalawo.

Zofunika! Thupi limaperekedwa kokha mosazindikira, mwanjira zina zovuta mu mawonekedwe a hypoglycemia zimatha kupweteka.

Bongo

Kuchuluka kwa mankhwalawa omwe angapangitse chithunzichi, akatswiri sanazindikirebe. Mlingo wambiri wowonjezera ungayambitse hypoglycemia. Kuukira kumayambira nthawi zambiri usiku kapena kupsinjika.

Fomu yofatsa imatha kuchotsedwa palokha: idyani chokoleti, chidutswa cha shuga kapena mankhwala olemera. A woipa mawonekedwe, wodwala akasiya kuzindikira, zimaphatikizapo intramuscular makonzedwe a 1 mg wa shuga / glucose njira kudzera m`mitsempha. Njirayi imatha kuchitika kokha ndi katswiri. Ngati chikumbumtima sichibwerera kwa munthuyo, shuga amathandizidwanso.

Zofunika! Sizoletsedwa kuwonjezera kapena kuchepetsa kuchuluka, komanso kuphonya mphindi yotsatira ya mankhwalawa, popeza pali kuthekera kwakukulu kwa chikomokere ndi kukokomeza kwa neuropathy.

Kuyanjana kwa mankhwala

Levemir imagwiritsidwa ntchito bwino limodzi ndi mankhwala ena: othandizira a hypoglycemic monga mapiritsi kapena ma insulin afupiafupi. Komabe, ndikosayenera kusakaniza mitundu ingapo ya insulin mkati mwa syringe yomweyo.

Kugwiritsa ntchito mankhwala ena kumasintha chizindikiro cha insulin. Chifukwa chake, othandizira a hypoglycemic, carbonic anhydrase, zoletsa, monoamine oxidases ndi ena amathandizira pakuchitika kwa chinthu chogwira ntchito.

Mahomoni, njira zakulera, mankhwala okhala ndi ayodini, antidepressants, danazole amatha kufooketsa mphamvu.

Ma salicylates, octreotide, komanso reserpine amatha kutsitsa ndikuwonjezera kufunikira kwa insulin, ndipo beta-blockers imatchinga zizindikiro za hypoglycemia, ndikuletsa kuchuluka kwa shuga.

Kuphatikizana ndi gulu la sulfite kapena thiol, komanso mitundu ya kulowetsedwa, kumakhala ndi zowononga.

Insulin Levemir - malangizo, ntchito, mtengo

Sichingakhale kukokomeza kunena kuti pobwera insulin analogues nthawi yatsopano idayamba m'miyoyo ya odwala matenda ashuga.

Chifukwa cha kapangidwe kake kapadera, zimapangitsa kuti azitha kuyendetsa glycemia bwino kwambiri kuposa kale. Insulin Levemir ndi m'modzi mwa oimira mankhwala amakono, analogue ya basal hormone.

Zawoneka posachedwa: ku Europe mu 2004, ku Russia patatha zaka ziwiri.

Levemir ali ndi mawonekedwe onse a insulin yayitali yayitali: imagwira ntchito mofananamo, popanda kupindika kwa maola 24, imayambitsa kuchepa kwa usiku hypoglycemia, sikuti imapangitsa kuti odwala azichita bwino, zomwe zimakhala zowona makamaka kwa matenda ashuga amtundu wa 2. Zotsatira zake ndizodziwikiratu komanso zimadalira kwambiri mawonekedwe a munthu kuposa NPH-insulin, ndiye kuti mankhwalawa ndikosavuta kusankha. M'mawu ochepa, ndikofunikira kuyang'anitsitsa mankhwalawa.

Malangizo achidule

Levemir ndiye kholo la kampani ya ku Danish ya Novo Nordisk, yomwe imadziwika ndi mankhwala othandizira odwala matenda ashuga. Mankhwalawa adadutsa maphunziro ambiri, kuphatikiza ana ndi achinyamata, pa nthawi yomwe ali ndi pakati.

Onsewa sanatsimikize chitetezo cha Levemir okha, komanso kuchita bwino kwambiri kuposa ma insulins omwe amagwiritsidwa ntchito kale.

Kuwongolera shuga kumatheka bwino mofananamo matenda amtundu woyamba wa shuga komanso m'mikhalidwe yokhala ndi vuto lochepa la mahomoni: mtundu 2 koyambirira kwa mankhwala a insulin komanso matenda a shuga.

Zambiri mwachidule za mankhwalawa kuchokera kuzomwe mungagwiritse ntchito:

KufotokozeraYankho lopanda utoto lokhala ndi U100, yodzaza ndi makatoni am'magalasi (Levemir Penfill) kapena ma cholembera a syringe omwe safuna kufatsa (Levemir Flexpen).
KupangaDzina ladziko lonse losagwirizana ndi gawo la Levemir (INN) ndi insulin. Kuphatikiza apo, mankhwalawa ali ndi zokometsera. Zida zonse zimayesedwa poizoni ndi carcinogenicity.
MankhwalaLimakupatsani mwayi wofanizira kumasulira kwa basal insulin. Amakhala ndi kusiyanasiyana kochepa, ndiye kuti, zotsatira zake zimasiyana pang'ono osati mwa wodwala m'modzi wokha yemwe ali ndi matenda ashuga masiku osiyanasiyana, komanso odwala ena. Kugwiritsa ntchito insulin Levemir kumachepetsa kwambiri chiopsezo cha hypoglycemia, zimawonjezera kuzindikira kwawo. Mankhwalawa pakali pano ndi insulini "yokhayo-yophatikiza", imakhudza thupi, imathandizira mawonekedwe a chidzalo.
Zomwe zimayamwaLevemir imapanga ma insulin ovuta kuphatikizira - hexamers, yomwe imamangiriza mapuloteni pamalo opangira jakisoni, kotero kuti kumasulidwa kwake kwa minofu yapansipansi kumakhala kuchepa komanso yunifolomu. Mankhwalawa alibe zambiri zapamwamba za Protafan ndi Humulin NPH. Malinga ndi wopanga, zomwe Levemir amachita zimakhala zosalala kuposa zomwe akupikisana naye kuchokera ku gulu limodzi la insulin - Lantus. Mwa nthawi yogwira ntchito, Levemir idutsa kokha mankhwala amakono komanso okwera mtengo a Tresiba, omwe amapangidwa ndi Novo Nordisk.
ZizindikiroMitundu yonse ya matenda a shuga omwe amafunikira insulin mankhwala kuti apatsidwe chipukuta misozi. Levemir imakhudzanso ana, odwala ndi achinyamata omwe, angagwiritsidwe ntchito kuphwanya chiwindi ndi impso. Ndi mtundu wa 2 shuga, kugwiritsa ntchito kwake molumikizana ndi othandizira a hypoglycemic ndikololedwa.
ContraindicationLevemir sayenera kugwiritsidwa ntchito:

  • Ndi chifuwa chachikulu cha insulini kapena chothandiza pa yankho,
  • mankhwalawa pachimake hyperglycemic zinthu,
  • m'mapopa a insulin.

Mankhwalawa amangoperekedwa pang'onopang'ono, makonzedwe amkati amaletsedwa.Kafukufuku wa ana osakwana zaka ziwiri sanachitepo, chifukwa chake gulu ili la odwala limanenedwanso mu contraindication. Komabe, insulin iyi imalembera ana aang'ono kwambiri.

Malangizo apaderaKuthetsa kwa Levemir kapena kutumikiridwa mobwerezabwereza kwa mlingo wosakwanira kumabweretsa kwambiri hyperglycemia ndi ketoacidosis. Izi ndizowopsa makamaka ndi matenda amtundu 1 shuga. Mlingo wowonjezera, kudya zakudya, kulibe zinthu zambiri zomwe zimakhala ndi hypoglycemia. Ndi kunyalanyaza kwa mankhwala a insulin komanso kusinthasintha kwapafupipafupi kwa shuga wambiri komanso wotsika, zovuta zamatenda a shuga zimayamba mofulumira.Ukufunika kwa Levemir kumawonjezereka ndi masewera, pa nthawi ya matenda, makamaka ndi kutentha thupi, panthawi yapakati, kuyambira theka lachiwiri. Kusintha kwa Mlingo wofunikira kumapangitsa kuti pachimake pakhale kutupa komanso kuchulukirachulukira.
MlingoMalangizowo akuwonetsa kuti kwa matenda amtundu 1 wa shuga, kuwerengetsa kwa munthu aliyense kwa wodwala aliyense. Ndi matenda amtundu wa 2, mlingo umayamba ndi magawo 10 a Levemir patsiku kapena mayunitsi a 0-0-0.2 pa kilogalamu ngati kulemera kwake ndikosiyana kwambiri ndi kuchuluka. Poyeserera, kuchuluka kumeneku kungakhale kokwanira ngati wodwala amatsatira zakudya zama carb otsika kapena ngati akuchita nawo masewera olimbitsa thupi. Chifukwa chake, ndikofunikira kuwerengera kuchuluka kwa insulin yayitali malinga ndi ma algorithms apadera, poganizira glycemia m'masiku ochepa.
KusungaLevemir, monga ma insulin ena, amafunika kutetezedwa pakuwala, kuzizira ndi kutentha kwambiri. Kukonzekera kovunda sikungasiyane mwanjira iliyonse ndi yatsopano, chifukwa chake chisamaliro chapadera chiyenera kulipidwa pazosungidwa. Makatsegulo otseguka amakhala kwa milungu isanu ndi umodzi pa kutentha kwa chipinda. Mabotolo a spare amasungidwa mufiriji, moyo wawo wa alumali kuyambira tsiku lopanga ndi miyezi 30.
MtengoMakatoni 5 a 3 ml (mayunitsi okwana 1,500) a Levemir Penfill mtengo kuchokera kuma ruble 2800. Mtengo wa Levemir Flexpen ndiwokwera pang'ono.

Kodi insulin levemir ikuyenda bwanji?

Levemir ndi insulin yayitali. Zotsatira zake ndizotalikirapo kuposa zamankhwala osokoneza bongo - chisakanizo cha insulin ya anthu ndi protamine. Pa mlingo wa mayunitsi 0,3. pa kilogalamu, mankhwalawa amagwira ntchito maola 24. Mlingo wochepera, wocheperako nthawi yogwira ntchito. Odwala omwe ali ndi matenda a shuga, kutsatira zakudya zamafuta ochepa, izi zitha kutha patatha maola 14.

Insulin yayitali silingagwiritsidwe ntchito kukonza glycemia masana kapena pogona. Ngati shuga wokwezeka wapezeka madzulo, ndikofunikira kupanga jakisoni waifupi wa insulin, ndipo pambuyo poti atulutse timadzi tambiri tomwe timatulutsa. Simungasakanize ma insulin analogi amtundu umodzi mu syringe yomweyo.

Kutulutsa Mafomu

Levemir insulin mu vial

Levemir Flexpen ndi Penfill amasiyana mawonekedwe okha, mankhwalawo ali ofanana. Penfill - awa ndi makatiriji omwe amatha kuyikidwa mu ma cholembera kapena kutumizira insulin kuchokera kwa iwo ndi syringe yovomerezeka.

Levemir Flexpen - pre-wodzazidwa ndi zolembera zopangira zomwe zimagwiritsidwa ntchito mpaka yankho litatha. Simungathe kuzikulitsanso. Ma cell amakulolani kuti mulowetse insulin muzowonjezera za 1 unit. Afunika kugula padera ndi singano za NovoFayn.

Kutengera ndi kukula kwa tinthu tating'onoting'ono, makamaka tating'ono (0.25 mm m'milimita) 6 mm kutalika kapena kupyapyala (0.3 mm) 8 mm amasankhidwa. Mtengo wa paketi ya singano 100 ndi pafupifupi ma ruble 700.

Levemir Flexpen ndi yoyenera kwa odwala omwe ali ndi moyo wokangalika komanso kusowa kwa nthawi. Ngati kufunika kwa insulini kuli kochepa, gawo limodzi la 1 sikulola kuti muimbire molondola mlingo womwe mukufuna. Kwa anthu otere, Levemir Penfill amalimbikitsidwa kuphatikiza cholembera cholondola kwambiri, mwachitsanzo, NovoPen Echo.

Mlingo woyenera

Mlingo wa Levemir amaonedwa kuti ndi wolondola ngati sikuti amasala kudya kokha, komanso hemoglobin wa glycated ali paliponse. Ngati chiphuphu cha shuga sichikwanira, mutha kusintha insulin yayitali masiku atatu aliwonse. Kuti mudziwe kukonza koyenera, wopangayo akuvomereza kuti atenge shuga wamba pamimba yopanda kanthu, masiku atatu omaliza akukhudzidwa pakuwerengera

Glycemia, mmol / lKusintha kwa MlingoMtengo wowongolera, mayunitsi
1010

Nkhani yofananira: Malamulo owerengera kuchuluka kwa insulin ya jakisoni

Ndondomeko ya jekeseni

  1. Ndi matenda a shuga 1 Malangizo akutsimikizira kukonzekera kwa insulin kawiri: mutadzuka ndi asanagone. Dongosolo lotere limapereka chindapusa kwabwino kwa odwala matenda ashuga kuposa amodzi. Mlingo amawerengedwa mosiyana. Kwa insulin yam'mawa - yozikidwa pa shuga ya tsiku ndi tsiku osala kudya, chifukwa chamadzulo - motengera zoyenera zake zamadzulo.

Ndi matenda a shuga a 2 onse osakwatira ndi awiri makonzedwe ndizotheka. Kafukufuku akuwonetsa kuti kumayambiriro kwa mankhwala a insulin, jakisoni imodzi patsiku ndikokwanira kukwaniritsa kuchuluka kwa shuga. Mankhwala okhazikika limodzi safuna kuti munthu awonjezere kuchuluka kwake. Popeza munthu amakhala ndi matenda a shuga kwa nthawi yayitali, insulin yayitali imakhala yanzeru kuthandizira kawiri patsiku.

Gwiritsani ntchito ana

Pofuna kuloleza kugwiritsa ntchito Levemir m'magulu osiyanasiyana a anthu, maphunziro akulu okhudzana ndi odzipereka amafunikira.

Kwa ana ochepera zaka ziwiri, izi zimalumikizidwa ndi zovuta zambiri, chifukwa chake, mu malangizo ogwiritsira ntchito, pali zoletsa pazaka. Zofananazo zilipo ndi ma insulini ena amakono. Ngakhale izi, Levemir imagwiritsidwa ntchito bwino mu makanda mpaka chaka.

Kuthandizirana nawo kumakhala kopambana monga mwa ana okulirapo. Malinga ndi makolo, palibe zoyipa.

Kusintha ku Levemir ndi NPH insulin ndikofunikira ngati:

Ndikofunikira kwambiri: Lekani kudyetsa mafia azakudya zonse. Ma Endocrinologists amatipangitsa kuti tiziwonongeratu ndalama pamapiritsi pomwe shuga m'magazi amatha kukhala ngati ma ruble 147 ... >> werengani nkhani ya Alla Viktorovna

  • shuga yosala kudya siyakhazikika,
  • hypoglycemia imawonedwa usiku kapena nthawi yamadzulo,
  • mwana wonenepa kwambiri.

Kuyerekeza kwa Levemir ndi NPH-insulin

Mosiyana ndi Levemir, onse a insulin omwe ali ndi protamine (Protafan, Humulin NPH ndi ma analogi awo) ali ndi kutchulidwa kwakukulu, komwe kumawonjezera chiopsezo cha hypoglycemia, kudumpha kwa shuga kumachitika tsiku lonse.

Ubwino Wotsimikiziridwa ndi Levemir:

  1. Ili ndi kuthekera kowonekeratu.
  2. Amachepetsa mwayi wa hypoglycemia: kwambiri ndi 69%, usiku ndi 46%.
  3. Zimayambitsa kuchepa pang'ono mu mtundu wa matenda ashuga a 2: m'masabata 26, kulemera kwa odwala ku Levemir kumawonjezera ndi ma kilogalamu 1.2, komanso odwala matenda ashuga a NPH-insulin ndi 2.8 kg.
  4. Imayang'anira njala, yomwe imayambitsa kuchepa kwa chidwi cha odwala omwe ali ndi kunenepa kwambiri. Anthu odwala matenda ashuga ku Levemir amathera pafupifupi kcal 160 / tsiku zochepa.
  5. Kuchulukitsa katulutsidwe ka GLP-1. Ndi matenda a shuga a 2, izi zimapangitsa kuti awonjezeke insulin yawo.
  6. Imakhala ndi phindu pa kagayidwe kamchere wamchere, komwe kumachepetsa chiopsezo cha matenda oopsa.

Drawback yokhayo ya Levemir poyerekeza ndi kukonzekera kwa NPH ndi mtengo wake wokwera. Zaka zaposachedwa, zalembedwera m'ndandanda wa mankhwala ofunikira, chifukwa chake odwala omwe ali ndi matenda ashuga amatha kupeza kwaulere.

Levemir ndi insulin yatsopano kwambiri, motero ilibe mafuta okwera mtengo. Malo omwe ali pafupi kwambiri komanso nthawi yayitali ndi mankhwala osokoneza bongo omwe ali m'gulu la insulin analogues - Lantus ndi Tujeo.

Kusunthira ku insulin ina kumafunanso kuti mupeze kuchuluka kwa mankhwalawa ndipo mosakayikitsa kumabweretsa kuwonongeka kwakanthawi pobwezeretsa matenda a shuga, chifukwa chake, mankhwalawa ayenera kusinthidwa pazifukwa zachipatala, mwachitsanzo, ndi tsankho la munthu payekha.

Kuwerenga: mndandanda wa mankhwala otchuka a insulin

Malangizo apadera

Kuchiza ndi Levemir kumachepetsa chiopsezo cha kugwidwa ndi hypoglycemia usiku ndipo nthawi yomweyo sikuti kumabweretsa kuwonda kwambiri. Izi, zimakupatsani mwayi wosinthira kuchuluka kwa yankho, sankhani mlingo woyenera, kuphatikiza ndi mapiritsi amtundu womwewo kuti muwongolere bwino.

Mukakonzekera ulendo wautali ndikusintha kwa nthawi, funsani dokotala.

Siyani kumwa ndikuchepetsa mulingo woletsedwa kupewa hypoglycemia.

Zizindikiro zakuyamba kuukira:

  • kumverera kwa ludzu
  • akukumbutsa
  • nseru
  • malo ogona
  • khungu lowuma
  • kukodza pafupipafupi
  • kusadya bwino
  • Mukatulutsa, mumanunkhira acetone.

Ndi kuwonjezeka kwa mlingo, kudumpha chakudya chovomerezeka, kuchuluka kwakukulu mosayembekezereka, hypoglycemia ikhoza kukhalanso. Kusamala kwambiri

Kuponderezedwa kwa thupi kumayambitsa kuchuluka kwa insulin. Mu matenda a chithokomiro, impso kapena chiwindi, kusintha kwa mlingo kumachitidwanso.

Zithunzi za 3D

Subcutaneous Solution1 ml
ntchito:
insulin100 PIERES (14.2 mg)
zokopa: glycerol, phenol, metacresol, nthaka (monga zinc acetate), sodium hydrogen phosphate dihydrate, sodium chloride, hydrochloric acid kapena sodium hydroxide, madzi a jekeseni
1 cholembera cha syringe chili ndi 3 ml ya yankho lofanana ndi 300 PIECES
1 unit ya insulin detemir ili ndi 0,142 mg ya insulin yopanda mchere, womwe umafanana ndi gawo limodzi la insulin (IU) yaumunthu

Levemir kapena Lantus - zomwe zili bwino

Wopanga adavumbulutsa zabwino za Levemir poyerekeza ndi mpikisano wake wamkulu - Lantus, yemwe adawonetsa mosangalala malangizo:

  • zochita za insulin ndizosatha
  • mankhwalawa amapatsa mphamvu zochepa.

Malinga ndi ndemanga, kusiyana kumeneku ndi kosavomerezeka, choncho odwala amakonda mankhwala, mankhwala omwe ndi osavuta kupeza m'derali.

Kusiyanitsa kofunikira ndikofunikira kwa odwala omwe amachepetsa insulin: Levemir imasakanikirana bwino ndi saline, ndipo Lantus amataya zinthu zake pang'ono atasungunuka.

Mimba ndi Levemir

Levemir sikukhudza chitukuko cha fetalChifukwa chake, angagwiritsidwe ntchito ndi amayi apakati, kuphatikizapo omwe ali ndi matenda a shuga. Mlingo wa mankhwala pa nthawi ya pakati pamafunika kusinthidwa pafupipafupi, ndipo ayenera kusankhidwa limodzi ndi adokotala.

Ndi matenda amtundu woyamba 1, odwala panthawi yomwe akubala mwana amakhalabe pa insulin yomweyo yomwe adalandira kale, ndiye kusintha kwake. Kusintha kuchokera ku mankhwala a NPH kupita ku Levemir kapena Lantus sikofunikira ngati shuga ndi yabwinobwino.

Ndi matenda a shuga gestational, nthawi zina zimakhala zotheka kukwaniritsa glycemia popanda insulin, pakudya kokha komanso masewera olimbitsa thupi. Ngati shuga amakwezedwa pafupipafupi, mankhwala a insulin amafunikira kuti muchepetse matenda a fetus mu fetus ndi ketoacidosis mwa amayi.

Ndemanga zambiri za odwala a Levemir ndi zabwino. Kuphatikiza pakupititsa patsogolo kayendedwe ka glycemic, odwala amawona kugwiritsa ntchito mosavuta, kulolera bwino, mabotolo abwino ndi zolembera, singano zowonda zomwe zimakupatsani mwayi kuti mupange jakisoni osapweteka. Ambiri odwala matenda ashuga amati hypoglycemia pa insulin iyi imakhala yocheperako komanso yofooka.

Ndemanga zoyipa ndizosowa. Amachokera makamaka kwa makolo a makanda omwe ali ndi matenda ashuga komanso azimayi omwe ali ndi matenda ashuga.

Odwala awa amafunika Mlingo wa insulini wochepetsedwa, motero Levemir Flexpen sakhala womasuka kwa iwo.

Ngati sipangakhale njira ina iliyonse, ndipo ndi mankhwala okhawo omwe angapezeke, odwala matenda ashuga amayenera kuchoka mu cholembera ndi kutulutsa zina ndi zina kapena kupanga jakisoni ndi syringe.

Zochita za Levemir ndizodabwitsa kwambiri amayamba masabata 6 atatha kutsegulidwa. Odwala omwe amafunikira insulin yayitali alibe nthawi yocheza ndi magawo 300 a mankhwalawa, ndiye kuti zotsalazo ziyenera kutayidwa.

Chonde dziwani: Kodi mumalota kuti muthetse matenda ashuga kamodzi? Phunzirani momwe mungathetsere matendawa, osagwiritsa ntchito mankhwala okwera mtengo pokhapokha ... >> werengani zambiri apa

Levemir: malangizo ogwiritsira ntchito, mtengo, ndemanga ndi fanizo

"Levemir" ndi mankhwala ochiritsira omwe amagwiritsidwa ntchito mogwirizana ndi malangizo omwe angagwiritsidwe ntchito kuteteza matenda a insulin, mosasamala kuchuluka kwa chakudya chomwe chatengedwa komanso zakudya zomwe mumadya.

Madokotala nthawi zambiri amalimbikitsa njira yothetsera vutoli kwa odwala awo kuti achepetse shuga.

Zomwe zimagwira mu kapangidwe kake ka mankhwala ndi katundu ndizofanana ndi insulin, yomwe imapangidwa m'thupi la munthu.

Mimba komanso kuyamwa

Palibe chovuta kutenga Levemir mutanyamula mwana, izi zimatsimikiziridwa ndi kafukufuku. Insulin sikuvulaza mwana wosabadwayo komanso amayi akewo ndi mlingo wosankhidwa bwino. Sichosokoneza. Ngati matenda a shuga sagwiritsidwa ntchito panthawiyi, izi zimabweretsa mavuto akulu. Mukamadyetsa, mankhwalawa amasinthidwanso.

Mu trimester yoyamba, kufunika kwa insulin kumatha kuchepa, ndipo chachiwiri ndi chachitatu chimayamba kuchuluka pang'ono. Pambuyo pobereka, mulingo wofunikira umakhala wofanana ndi pathupi pathupi.

Gwiritsani ntchito muubwana ndi ukalamba

Kwa ana, mlingo wa insulin amawerengedwa potengera zakudya zomwe amatsatira. Ngati pali zakudya zambiri zomwe zili ndi zakudya zochepa zamafuta m'zakudya, ndiye kuti mlingo wake udzakhala wochepa. Ndi chimfine ndi chimfine, mlingo wake ufunika kuwonjezeka nthawi 1.5-2.

Okalamba, shuga wamagazi amayang'aniridwa bwino. Mlingo amawerengedwa mosamalitsa payekhapayekha, makamaka kwa iwo omwe ali ndi matenda a impso ndi chiwindi. Ma pharmacokinetics mwa odwala achinyamata ndi okalamba si osiyana.

Migwirizano ndi magwiritsidwe akusungidwa

Sungani mankhwalawo mufiriji pa 2-8 ° C. Cholembera chimbale chokha sichimafunikira kuti chichepe. Pamodzi ndi zomwe zili mu cartridge, imatha kusungidwa kwa mwezi ndi theka kutentha kwa chipinda. Chipewa chimathandiza kuteteza zomwe zili mu syringe kuchokera ku kuwala kwa kuwala. Mankhwalawa ndi oyenera kugwiritsidwa ntchito pakatha miyezi 30 kuchokera tsiku lomwe adamasulidwa. Amangotulutsidwa ndi mankhwala okha.

Mutha kuyeretsa cholembera ndi thonje swab choviikidwa mu njira ya mowa. Kumiza m'madzi ndi kuponyera nkoletsedwa. Ikaponyedwa, chogwirira chingawonongeke ndipo zomwe zili mkati mwake zikhwere.

Fananizani ndi fanizo

MankhwalaMapindu akeZoyipaMtengo, pakani.
LantusImakhala ndi mphamvu yayitali - kupindula kwatsopano pochiza matenda ashuga. Imagwira mokhazikika, popanda nsonga. Imafanana ndi kuchuluka kwa insulin ya munthu wathanzi Ngati mukufunikira kulowa mulingo waukulu wa insulin, ndibwino kusankha njirayi.Amakhulupirira kuti mankhwalawa amawonjezera mwayi wokhala ndi khansa poyerekeza ndi ena ofanana. Koma izi sizikutsimikiziridwa.Kuyambira 1800
TujeoAmachepetsa chiopsezo cha hypoglycemia, makamaka usiku. Glargine yatsopano ya Sanofi ikupita patsogolo kwambiri. Zovomerezeka mpaka maola 35. Kugwiritsa ntchito poyang'anira glycemic.Sitha kugwiritsidwa ntchito pochiza matenda ashuga a ketoacidosis. Ndikosayenera kutenga ana ndi amayi apakati. Ndi matenda a impso ndi chiwindi, sizinasankhidwe.Kuyambira 2200
ProtafanImakhala ndi kutalika kwa nthawi yayitali. Amawerengera amayi omwe ali ndi pakati. Oyenera T1DM ndi T2DM. Amathandizira magawo a shuga m'magazi bwino.Zingayambitse kuyabwa pakhungu, redness, kutupa.Kuyambira 800
RosinsulinOtetezeka kwa mkaka ndi pakati. Mitundu itatu imapangidwa (P, C ndi M), yomwe imasiyanitsidwa ndi kuthamanga ndi nthawi yowonekera.Sioyenera aliyense, zonse zimatengera umunthu wake.Kuyambira 1100
TresibaChofunikira chachikulu ndi insulin degludec. Momwe amachepetsa kwambiri zochitika za hypoglycemia. Kusunga shuga wokhazikika tsiku lonse. Zovomerezeka kwa maola opitilira 40.Osakhala yoyenera kuthandizira ana, kunyambita ndi amayi apakati. Ochepa omwe amagwiritsidwa ntchito pochita. Zimayambitsa zovuta.Kuyambira 8000.

Malinga ndi akatswiri, ngati pambuyo pa kumwa kamodzi pa insulini palibe kusintha kosintha kwa shuga, ndikofunika kupatsidwa analog yochepa.

Levemir ndi wabwino kwambiri pochiza odwala matenda ashuga. Chida ichi chamakono komanso chotsimikiziridwa chikuthandizira kuchepa kwamwazi wamagazi.

Irina, wazaka 27, Moscow.

"Poyamba, ndidakana kukana Levemir. Ndani akufuna kutenga insulin kapena kulemera kowonjezera? Dotolo adanditsimikizira kuti sizotheka kuchira kwa iye ndipo sanayambitse kudalira. Anandiika 6 ma insulin kamodzi patsiku.

Koma zodandaula sizinathe.Kodi nditha kubereka mwana wathanzi, kodi padzakhala mavuto ndi kukula kwake? Mankhwalawa ndi okwera mtengo. Sindinazindikire mavuto aliwonse kunyumba; mwanayo adabadwa mosatekeseka. Nditabereka, ndinasiya jakisoni wa Levemir;

Chifukwa chake ndimalimbikitsa. ”

Eugene, wazaka 43, Moscow.

“Ndili ndi matenda ashuga 1 kuyambira ndili mwana. M'mbuyomu, kunali kofunikira kutola insulini mu syringe kuchokera ku ampoules, kuyeza mayunitsi ndikudzibaya nokha. Ma syringe amakono omwe ali ndi cartulin ya insulin ndiwosavuta, ali ndi mfundo yoti azitha kuyika manambala. Mankhwalawa amachita mosamalitsa malinga ndi malangizo, ndimapita nawo maulendo azamalonda, zonse ndizopambana. Ndikukulangizani. ”

Huseyn, wazaka 40, Moscow.

Kwa nthawi yayitali sindimatha kuthana ndi vuto la shuga m'mawa. Adasinthira ku Levemir. Gawani majakisoni 4, omwe ndimachita kwa maola 24. Ndimatsatira zakudya zamafuta ochepa. Patatha mwezi umodzi kusinthaku kupita ku boma latsopano, shuga sanathenso. Tithokoze opanga. ”

Levemir Flexpen ndi Penfil - malangizo, ntchito, mayendedwe, ndemanga

Levemir ndi mankhwala a hypoglycemic omwe ali ofanana mu kapangidwe kake ka mankhwala ndi zochita kwa insulin yaumunthu. Mankhwalawa ali m'gulu la anthu omwe amapanganso insulin.

Levemir Flexpen ndi cholembera cha insulin chapadera ndi chothandizira. Chifukwa cha izo, insulin imatha kutumizidwa kuchokera ku 1 unit mpaka 60 unit. Kusintha kwa Mlingo kumapezeka mgulu limodzi.

Pa mashelu apachipatala mungapeze Levemir Penfill ndi Levemir Flekspen. Kodi amasiyana bwanji wina ndi mnzake? Kapangidwe konse ndi mlingo, njira ya makonzedwe ali chimodzimodzi. Kusiyana pakati pa oyimilira kuli pakumasulidwa. Levemir Penfill ndi makatoni omwe angathe kusintha m'malo mwa cholembera. Ndipo Levemir Flekspen ndi cholembera chimbale chotayika chomwe chili ndi makatoni omangidwa mkati.

Levemir amagwiritsidwa ntchito kuti azisunga insulin yamagazi kwambiri, mosasamala zakudya.

Chofunikira chachikulu pa mankhwalawa ndi kunyansidwa ndi insulin. Ndi insulin yamaumboni yaumunthu yomwe imapangidwa pogwiritsa ntchito chibadwa cha bakiteriya ya Saccharomyces cerevisiae. Mlingo wa yogwira 1 mg wa yankho ndi 100 IU kapena 14.2 mg. Komanso, 1 unit ya recombinant insulin Levemir ndi ofanana 1 unit ya insulin ya munthu.

Zowonjezera zina zimathandizira. Gawo lililonse limayang'anira ntchito zina. Amakhazikitsa kapangidwe ka yankho, amapereka zofunika zapadera zamankhwala, ndikuwonjezera nthawi yosungirako ndi moyo wa alumali.

Komanso, zinthuzi zimathandizira kukonza komanso kukonza ma pharmacokinetics ndi ma pharmacodynamics a kantheya kogwira ntchito: amasintha bioavailability, kupangika kwa minofu, kuchepetsa kumangiriza kwa mapuloteni amwazi, kuwongolera kagayidwe kazinthu ndi njira zina zochotsera.

Zinthu zina zotsatirazi zimaphatikizidwa ndi yankho la mankhwalawa:

  • Glycerol - 16 mg,
  • Metacresol - 2.06 mg,
  • Zink acetate - 65.4 mcg,
  • Phenol - 1,8 mg
  • Sodium Chloride - 1.17 mg
  • Hydrochloric acid - q.s.,
  • Hydrophosphate dihydrate - 0,89 mg,
  • Madzi a jakisoni - mpaka 1 ml.

Cholembera chilichonse kapena cartridge imakhala ndi 3 ml ya yankho kapena 300 IU ya insulin.

Mankhwala

Levemir insulin ndi mawonekedwe a insulin yaumunthu yokhala ndi nthawi yayitali, yosanja mawonekedwe. Kuchitidwa kwa mtundu wosachedwa kumachitika chifukwa cha kuphatikiza kwakukulu komwe kumayenderana ndi ma mamolekyulu a mankhwala.

Amanganso ena kumapuloteni m'dera lamatumbo. Zonsezi zimachitika pamalo operekera jakisoni, kotero kuti insulin ya insulin imalowera m'magazi pang'onopang'ono.

Ndipo zimakhala zofunikira zimalandira mlingo wofunikira pambuyo pake ndi ena oimira insulin.

Njira izi zimathandizira kugawa mankhwalawa, omwe amathandiza kuyamwa komanso chidziwitso cha kagayidwe.

Akuluakulu analimbikitsa mlingo wa 0,2-0.4 U / kg umafika hafu ya mphamvu pambuyo maola atatu.Nthawi zina, nthawi imeneyi imatha kuchedwa mpaka maola 14.

Zizindikiro ndi contraindication

Chizindikiro chokhacho chogwiritsira ntchito Levemir ndikuzindikira kwa matenda a shuga omwe amadalira odwala a shuga ndi ana opitirira zaka 2.

Contraindled pakumagwiritsa ntchito mankhwalawa ndi kupezeka kwa tsankho kwa chinthu chachikulu chothandizira ndi zigawo zothandizira.

Komanso, kudya kumapangidwa pakati pa ana osaposa zaka ziwiri chifukwa chosowa maphunziro azachipatala m'gulu la odwala.

Levemir: malangizo ogwiritsira ntchito. Momwe mungasankhire mlingo. Ndemanga

Insulin Levemir (detemir): phunzirani zonse zomwe mukufuna. Pansipa mupeza malangizo atsatanetsatane ogwiritsira ntchito olembedwa mchilankhulo. Dziwani:

Levemir ndi insulin yowonjezera (basal), yomwe imapangidwa ndi kampani yotchuka komanso yolemekezeka yapadziko lonse Novo Nordisk. Mankhwalawa agwiritsidwa ntchito kuyambira m'ma 2000s. Anakwanitsa kutchuka pakati pa odwala matenda ashuga, ngakhale insulin Lantus ili ndi gawo lalikulu pamsika. Werengani ndemanga zenizeni za odwala omwe ali ndi matenda amtundu wa 2 komanso matenda amitundu iwiri, komanso zomwe ana angagwiritse ntchito.

Komanso phunzirani zamankhwala othandizira omwe amasunga magazi anu kukhala 3.9-5,5 mmol / L khola maola 24 patsiku, monga momwe mungakhalire ndi anthu athanzi. Dongosolo la Dr. Bernstein, amene akhala ndi matenda ashuga kwa zaka zopitilira 70, amalola akuluakulu ndi ana odwala matenda ashuga kudziteteza ku zovuta zowopsa.

Long insulin levemir: Nkhani zatsatanetsatane

Chidwi chachikulu chimaperekedwa polamulira matenda ashuga. Levemir ndi mankhwala osankhidwa kwa amayi apakati omwe ali ndi shuga wambiri. Kafukufuku wovuta watsimikizira chitetezo chake komanso kugwira ntchito bwino kwa amayi oyembekezera, komanso kwa ana kuyambira zaka ziwiri.

Kumbukirani kuti insulin yowonongeka imakhala yowoneka bwino kwambiri. Ubwino wa mankhwalawa sungadziwike ndi maonekedwe ake. Chifukwa chake, sizoyenera kugula Levemir yokhala m'manja, ndikulengeza mwachinsinsi. Gulani mumasitolo akuluakulu odziwika omwe antchito ake amadziwa malamulo osungira ndipo si aulesi kwambiri kuti athe kutsatira.

Kodi levemir ndi insulini ya chochita? Kodi ndizitali kapena zazifupi?

Levemir ndi insulin wa nthawi yayitali. Mlingo uliwonse womwe umaperekedwa umachepetsa shuga mkati mwa maola 18-24. Komabe, odwala matenda ashuga omwe amatsata zakudya zama carb ochepa amafunika Mlingo wochepetsetsa, 2-8 nthawi yotsika kuposa wamba.

Pogwiritsa ntchito mankhwalawa, mphamvu ya mankhwalawa imatha mofulumira, mkati mwa maola 10-16. Mosiyana ndi wastani insulin Protafan, Levemir alibe chiwonetsero chokwanira kuchitapo kanthu.

Samalani ndi mankhwala atsopano a Tresib, omwe amakhala nthawi yayitali, mpaka maola 42, komanso bwino.

Levemir si inshuwaransi yayifupi. Sikoyenera malo omwe muyenera kuthana ndi shuga msanga. Komanso, siyenera kunenedwa musanadye chakudya kuti mugwirizane ndi chakudya chomwe odwala matenda ashuga akukonzekera kudya. Pazifukwa izi, kukonzekera kwakanthawi kapena ultrashort kumagwiritsidwa ntchito. Werengani nkhani yakuti “Mitundu ya Insulin ndi Zotsatira Zawo” mwatsatanetsatane.

Onerani kanema wa Dr. Bernstein. Dziwani chifukwa chake Levemir ali bwino kuposa Lantus. Mvetsetsani kangati patsiku muyenera kulidulira ilo komanso nthawi yanji. Onani kuti mukusunga insulini yanu molondola kuti isawonongeke.

Momwe mungasankhire mlingo?

Mlingo wa Levemir ndi mitundu ina yonse ya insulin uyenera kusankhidwa payekhapayekha. Kwa odwala matenda ashuga akuluakulu, pali malingaliro oyambira kuti ayambe ndi 10 PIECES kapena 0,1-0.2 PIECES / kg.

Komabe, kwa odwala omwe amatsata zakudya zama carb otsika kwambiri, mankhwalawa azikhala okwera kwambiri. Onani shuga wanu wamagazi masiku angapo. Sankhani mulingo woyenera wa insulin pogwiritsa ntchito zomwe mwalandira.

Werengani zambiri mu nkhani "Kuwerengera Mlingo wa insulin yayitali usiku ndi m'mawa."

Kodi mankhwalawa amafunika kuti alowetse ndani mwa mwana wazaka 3?

Zimatengera zakudya zamtundu wanji mwana wodwala matenda ashuga.Ngati adasinthidwa kudya zakudya zama carb ochepa, ndiye kuti Mlingo wochepetsetsa kwambiri, ngati homeopathic, ungafunike.

Mwinanso, muyenera kulowa ku Levemir m'mawa ndi madzulo muzinthu zosaposa 1 unit. Mutha kuyamba ndi mayunitsi 0,25. Kuti mupeze jekeseni yotsika bwino, ndikofunikira kuthira njira yofayira jakisoni.

Werengani zambiri za izo apa.

Pakazizira, poizoni wa chakudya ndi matenda ena opatsirana, Mlingo wa insulin uyenera kuchuluka nthawi 1.5. Chonde dziwani kuti kukonzekera kwa Lantus, Tujeo ndi Tresiba sikungathe kuchepetsedwa.

Chifukwa chake, kwa ana aang'ono a mitundu yayitali ya insulin, ndi Levemir ndi Protafan yekhayo amene atsalira. Phunzirani nkhani ya “Matenda a Ana A shuga.”

Phunzirani momwe mungatalikitsire nthawi yanu ya tchuthi ndikukhazikitsa mtundu wabwino wama glucose.

Mitundu ya insulini: Momwe mungasankhire mankhwala a insulin yayitali usiku ndi m'mawa Muwerengera kuchuluka kwa insulin musanadye chakudya

Momwe mungasinthire Levemir? Kangati patsiku?

Levemir sikokwanira kumangodula kamodzi patsiku. Iyenera kuperekedwa kawiri pa tsiku - m'mawa ndi usiku. Kuphatikiza apo, zochita zamankhwala a madzulo nthawi zambiri sizikhala zokwanira usiku wonse. Chifukwa cha izi, odwala matenda ashuga amatha kukhala ndi zovuta zam'mawa m'mimba yopanda kanthu. Werengani nkhani yoti "Shuga pamimba yopanda kanthu m'mawa: momwe mungabwezeretsere zodabwitsa". Komanso werengani za "insulin management: momwe ndi momwe mungabayitsire".

Kodi mankhwalawa angafanane ndi Protafan?

Levemir ndi wabwino kwambiri kuposa Protafan. Majekeseni a insulin a Protafan satenga nthawi yayitali, makamaka ngati milingo yotsika. Mankhwalawa amakhala ndi puloteni wa nyama, zomwe nthawi zambiri zimayambitsa matupi awo.

Ndikwabwino kukana kugwiritsa ntchito protafan insulin. Ngakhale mankhwalawa akaperekedwa kwaulere, ndipo mitundu ina ya insulin yowonjezera idzayenera kugulidwa ndi ndalama. Pitani ku Levemir, Lantus kapena Tresiba.

Werengani zambiri mu nkhani "Mitundu ya Insulin ndi Zotsatira Zawo".

Levemir Penfill ndi Flekspen: Kusiyana kwake ndi kotani?

Flekspen ndi cholembera chimbale momwe mavekitala a inshuwaransi ya Levemir amaikiramo.

Penfill ndi mankhwala a Levemir omwe amagulitsidwa popanda zolembera kuti mugwiritse ntchito syringes yokhazikika ya insulin. Ma cholembera a Flexspen ali ndi gawo la 1 unit.

Izi zitha kukhala zosokoneza mankhwalawa a shuga kwa ana omwe amafunikira kuchuluka. Zikatero, ndikofunika kupeza ndikugwiritsa ntchito Penfill.

Levemir alibe ma analogu otsika mtengo. Chifukwa mawonekedwe ake amatetezedwa ndi patent yomwe kuvomerezeka kwake sikunathe. Pali mitundu ingapo yofanana ya insulin yayitali kuchokera kwa opanga ena. Awa ndi mankhwala Lantus, Tujeo ndi Tresiba.

Mutha kuphunzira mwatsatanetsatane nkhani iliyonse. Komabe, mankhwalawa onse siotsika mtengo. Insulin-average insulin, monga Protafan, imakhala yotsika mtengo. Komabe, zili ndi zolakwika zazikulu chifukwa chake Dr. Bernstein ndi tsamba la odwala endocrin.

com sikulimbikitsa kugwiritsa ntchito.

Levemir kapena Lantus: ndi insulin iti bwino?

Yankho lachilendo la funsoli laperekedwa munkhaniyi ya insulin Lantus. Ngati Levemir kapena Lantus akukwiyirani, pitilizani kugwiritsa ntchito. Musasinthe mankhwala amitundu ina pokhapokha pakufunika.

Ngati mukukonzekera kuyamba kubayitsa insulin yayitali, ndiye yesetsani Levemir. Insulin yatsopano ya Treshiba ndiyabwino kuposa Levemir ndi Lantus, chifukwa imatenga nthawi yayitali komanso bwino.

Komabe, zimawononga pafupifupi katatu katatu.

Levemir pa mimba

Kafukufuku wamkulu wazachipatala adachitidwa omwe adatsimikizira chitetezo ndi kuyendetsa bwino kwa kayendetsedwe ka Levemir pa nthawi yapakati.

Mitundu yampikisano ya insulin Lantus, Tujeo ndi Tresiba sangadzitame chifukwa cha umboni wabwino wotetezedwa.

Ndikofunika kuti mayi woyembekezera yemwe ali ndi shuga wambiri amvetsetse momwe angawerengere Mlingo woyenera.

Insulin siyowopsa kwa mayi kapena kwa mwana wosabadwayo, malinga ngati mankhwalawo asankhidwa molondola. Matenda a shuga oyembekezera, ngati atasiyidwa, amatha kubweretsa mavuto akulu. Chifukwa chake, lembani molimba mtima Levemir ngati dokotala wakuuzani kuti muchite izi. Yesani kuchita popanda kulandira insulin, kutsatira zakudya zabwino. Werengani nkhani zakuti “Amayi Azipakati” ndi “Gestational Diabetes” kuti mumve zambiri.

Levemir wakhala akugwiritsidwa ntchito kuwongolera matenda a shuga a 2 ndikulemba mtundu 1 kuyambira m'ma 2000s. Ngakhale mankhwalawa ali ndi mafani ocheperako kuposa a Lantus, ndemanga zokwanira zasonkhana pazaka zambiri. Ambiri mwaiwo ndi abwino. Odwala amati insulin imachepetsa shuga m'magazi. Nthawi yomweyo, chiopsezo cha hypoglycemia ndichochepa kwambiri.

Gawo lalikulu la ndemanga zalembedwa ndi azimayi omwe amagwiritsa ntchito Levemir pa nthawi yoyembekezera kuti athe kuthana ndi matenda ashuga. Kwenikweni, odwala awa amakhutira ndi mankhwalawo. Sichosokoneza, jakisoni wobala mwana atatha kuthetsedwa popanda mavuto. Kulondola ndikofunikira kuti musapange cholakwika ndi muyezo, koma ndi kukonzekera kwina kwa insulin ndi chimodzimodzi.

Malinga ndi odwala, chododometsa chachikulu ndikuti cartridge yoyambira iyenera kugwiritsidwa ntchito mkati mwa masiku 30. Ino ndi nthawi yochepa kwambiri. Nthawi zambiri mumayenera kutaya ndalama zonse zosagwiritsidwa ntchito, ndipo pambuyo pake, ndalama zawalipira. Koma mankhwala onse opikisana ali ndi vuto lomweli. Ndemanga za odwala matenda ashuga zimatsimikizira kuti Levemir ndiwopambana ndi pafupifupi insulin Protafan pankhani zonse zofunika.

Insulin LEVEMIR: ndemanga, malangizo, mtengo

Levemir Flexpen ndi analogue of insulin yamunthu ndipo imakhala ndi hypoglycemic. Levemir imapangidwa ndikuwonjezera kwa DNA yomwe ikubwerekanso pogwiritsa ntchito Saccharomyces cerevisiae.

Ndi osungunuka basalle a insulin yaumunthu yokhala ndi mphamvu yayitali komanso mawonekedwe a pang'onopang'ono pochita, osasinthika kwambiri poyerekeza ndi insulin glargine ndi isofan-insulin.

Kuchitikira kwakanthawi kwa mankhwalawa kumachitika chifukwa chakuti ma molekyulu a insulir amatha kudziwonetseratu pawebusayiti, komanso kumangiriza ku albumin pophatikiza ndi unyolo wamafuta acid.

Dermul ya Detemir imagwira zotumphukira zamafupipafupi pang'onopang'ono kuposa isofan-insulin. Kuphatikizika kwa njira zogwiritsidwira ntchito masiku ano kumathandizanso kuti mbiri ya Levemir Penfill ichitike kuposa isofan-insulin.

Mukamangirira ma receptor enieni pa cytoplasmic membrane wa insulin, insulin imapanga mawonekedwe apadera omwe amalimbikitsa kapangidwe kazinthu zingapo zofunika za ma enzymes mkati mwa maselo, monga hexokinase, glycogen synthetase, pyruvate kinase ndi ena.

Chizindikiro chachikulu pakugwiritsa ntchito Levemir Flexpen ndi matenda ashuga.

Contraindication

  1. Kusagwirizana ndi zinthu zazikulu komanso zowonjezera pazogwira ntchito.
  2. Zaka mpaka zaka ziwiri.

Malangizo ogwiritsira ntchito (mlingo)

Kutalika kwa mankhwalawa kumatengera mlingo. Kumayambiriro kwa mankhwalawa kuyenera kunenedwa kamodzi patsiku, makamaka tsiku lomaliza chakudya chamadzulo kapena musanagone. Kwa odwala omwe sanalandire insulin m'mbuyomu, Mlingo woyambirira ndi magawo 10 kapena magawo 0,1-0.2 pa kilogalamu ya thupi.

Kwa odwala omwe akhala akugwiritsa ntchito hypoglycemic kwa nthawi yayitali, madokotala amalimbikitsa kuchuluka kwa pafupifupi 0,4,4 magawo a kilogalamu iliyonse ya thupi. Kuchitikaku kumayambira pambuyo pa maola 3-4, nthawi zina mpaka maola 14.

Mlingo woyambira nthawi zambiri umaperekedwa nthawi 1-2. Mutha kulowa yomweyo kamodzi kapena kugawa kawiri. Pachiwiri, mankhwalawa amagwiritsidwa ntchito m'mawa komanso madzulo, nthawi yolumikizirana imayenera kukhala maola 12. Mukasintha kuchokera ku mtundu wina wa insulin kupita ku Levemir, mlingo wa mankhwalawa sungasinthe.

Mlingo wawerengedwa ndi endocrinologist potengera izi:

  • kuchuluka kwa zochitika
  • zopatsa thanzi
  • shuga
  • kuopsa kwa matenda,
  • zochitika tsiku ndi tsiku
  • kukhalapo kwa matenda oyanjana.

Mankhwalawa amatha kusinthidwa ngati pakufunika opaleshoni.

Zotsatira zoyipa

Pafupifupi 10% ya odwala amafunsira limodzi matendawa. Mu theka la milandu, iyi ndi hypoglycemia. Zotsatira zina pambuyo pa makonzedwe zimawonetsedwa ngati kutupa, redness, kupweteka, kuyabwa, kutupa. Kuwonongeka kumatha kuchitika. Zotsatira zoyipa zimatha patatha milungu ingapo.

Nthawi zina vutoli limakulirakulira chifukwa cha kuchuluka kwa matenda ashuga, zimachitika mwanjira inayake: matenda a shuga. Cholinga cha izi ndikusunga kuchuluka kwa glucose komanso kupewa glycemia. Thupi limapangidwanso, ndipo likasinthana ndi mankhwalawo, Zizindikiro zimapita zokha.

Mwa zina zoyipa zomwe zimachitika, zomwe ambiri ndi:

  • Kulakwitsa kwa chapakati mantha dongosolo (kuchuluka kumva kupweteka, kumva mphamvu za malekezero, kusokonekera kwamphamvu kuona ndi kuona kopepuka, kumva kugunda kapena kugunda kwamphamvu)
  • zovuta zamagulu kagayidwe kazakudya (hypoglycemia),
  • urticaria, kuyabwa, ziwengo, mantha anaphylactic,
  • zotumphukira edema
  • matenda a adipose minofu, zomwe zimatsogolera kusintha kwa mawonekedwe amthupi.

Onsewa amaphunzitsidwa pogwiritsa ntchito mankhwala osokoneza bongo. Ngati izi sizikuthandizani, dokotala amadzatenga mankhwalawo.

Bongo

Kuchuluka kwa mankhwalawa omwe angapangitse chithunzichi, akatswiri sanazindikirebe. Mlingo wambiri wowonjezera ungayambitse hypoglycemia. Kuukira kumayambira nthawi zambiri usiku kapena kupsinjika.

Fomu yofatsa imatha kuchotsedwa palokha: idyani chokoleti, chidutswa cha shuga kapena mankhwala olemera. A woipa mawonekedwe, wodwala akasiya kuzindikira, zimaphatikizapo intramuscular makonzedwe a 1 mg wa shuga / glucose njira kudzera m`mitsempha. Njirayi imatha kuchitika kokha ndi katswiri. Ngati chikumbumtima sichibwerera kwa munthuyo, shuga amathandizidwanso.

Kuyanjana kwa mankhwala

Levemir imagwiritsidwa ntchito bwino limodzi ndi mankhwala ena: othandizira a hypoglycemic monga mapiritsi kapena ma insulin afupiafupi. Komabe, ndikosayenera kusakaniza mitundu ingapo ya insulin mkati mwa syringe yomweyo.

Kugwiritsa ntchito mankhwala ena kumasintha chizindikiro cha insulin. Chifukwa chake, othandizira a hypoglycemic, carbonic anhydrase, zoletsa, monoamine oxidases ndi ena amathandizira pakuchitika kwa chinthu chogwira ntchito.

Mahomoni, njira zakulera, mankhwala okhala ndi ayodini, antidepressants, danazole amatha kufooketsa mphamvu.

Ma salicylates, octreotide, komanso reserpine amatha kutsitsa ndikuwonjezera kufunikira kwa insulin, ndipo beta-blockers imatchinga zizindikiro za hypoglycemia, ndikuletsa kuchuluka kwa shuga.

Kuphatikizana ndi gulu la sulfite kapena thiol, komanso mitundu ya kulowetsedwa, kumakhala ndi zowononga.

Kuyenderana ndi mowa

Zakumwa zokhala ndi zakumwa zoledzeretsa zimatha kuchulukitsa kapena kukulitsa mphamvu ya hypoglycemic ya kukonzekera kwa insulin, koma mowa uyenera kutengedwa ndi odwala matenda a shuga mosamala kwambiri, chifukwa umakhudza kagayidwe kazakudya m'thupi.

Malangizo apadera

Kuchiza ndi Levemir kumachepetsa chiopsezo cha kugwidwa ndi hypoglycemia usiku ndipo nthawi yomweyo sikuti kumabweretsa kuwonda kwambiri. Izi, zimakupatsani mwayi wosinthira kuchuluka kwa yankho, sankhani mlingo woyenera, kuphatikiza ndi mapiritsi amtundu womwewo kuti muwongolere bwino.

Mukakonzekera ulendo wautali ndikusintha kwa nthawi, funsani dokotala.

Zizindikiro zakuyamba kuukira:

  • kumverera kwa ludzu
  • akukumbutsa
  • nseru
  • malo ogona
  • khungu lowuma
  • kukodza pafupipafupi
  • kusadya bwino
  • Mukatulutsa, mumanunkhira acetone.

Ndi kuwonjezeka kwa mlingo, kudumpha chakudya chovomerezeka, kuchuluka kwakukulu mosayembekezereka, hypoglycemia ikhoza kukhalanso. Kusamala kwambiri

Kuponderezedwa kwa thupi kumayambitsa kuchuluka kwa insulin. Mu matenda a chithokomiro, impso kapena chiwindi, kusintha kwa mlingo kumachitidwanso.

Mimba komanso kuyamwa

Palibe chovuta kutenga Levemir mutanyamula mwana, izi zimatsimikiziridwa ndi kafukufuku. Insulin sikuvulaza mwana wosabadwayo komanso amayi akewo ndi mlingo wosankhidwa bwino. Sichosokoneza. Ngati matenda a shuga sagwiritsidwa ntchito panthawiyi, izi zimabweretsa mavuto akulu. Mukamadyetsa, mankhwalawa amasinthidwanso.

Mu trimester yoyamba, kufunika kwa insulin kumatha kuchepa, ndipo chachiwiri ndi chachitatu chimayamba kuchuluka pang'ono. Pambuyo pobereka, mulingo wofunikira umakhala wofanana ndi pathupi pathupi.

Gwiritsani ntchito muubwana ndi ukalamba

Kwa ana, mlingo wa insulin amawerengedwa potengera zakudya zomwe amatsatira. Ngati pali zakudya zambiri zomwe zili ndi zakudya zochepa zamafuta m'zakudya, ndiye kuti mlingo wake udzakhala wochepa. Ndi chimfine ndi chimfine, mlingo wake ufunika kuwonjezeka nthawi 1.5-2.

Okalamba, shuga wamagazi amayang'aniridwa bwino. Mlingo amawerengedwa mosamalitsa payekhapayekha, makamaka kwa iwo omwe ali ndi matenda a impso ndi chiwindi. Ma pharmacokinetics mwa odwala achinyamata ndi okalamba si osiyana.

Migwirizano ndi magwiritsidwe akusungidwa

Sungani mankhwalawo mufiriji pa 2-8 ° C. Cholembera chimbale chokha sichimafunikira kuti chichepe. Pamodzi ndi zomwe zili mu cartridge, imatha kusungidwa kwa mwezi ndi theka kutentha kwa chipinda. Chipewa chimathandiza kuteteza zomwe zili mu syringe kuchokera ku kuwala kwa kuwala. Mankhwalawa ndi oyenera kugwiritsidwa ntchito pakatha miyezi 30 kuchokera tsiku lomwe adamasulidwa. Amangotulutsidwa ndi mankhwala okha.

Mutha kuyeretsa cholembera ndi thonje swab choviikidwa mu njira ya mowa. Kumiza m'madzi ndi kuponyera nkoletsedwa. Ikaponyedwa, chogwirira chingawonongeke ndipo zomwe zili mkati mwake zikhwere.

Fananizani ndi fanizo

MankhwalaMapindu akeZoyipaMtengo, pakani.
LantusImakhala ndi mphamvu yayitali - kupindula kwatsopano pochiza matenda ashuga. Imagwira mokhazikika, popanda nsonga. Imafanana ndi kuchuluka kwa insulin ya munthu wathanzi Ngati mukufunikira kulowa mulingo waukulu wa insulin, ndibwino kusankha njirayi.Amakhulupirira kuti mankhwalawa amawonjezera mwayi wokhala ndi khansa poyerekeza ndi ena ofanana. Koma izi sizikutsimikiziridwa.Kuyambira 1800
TujeoAmachepetsa chiopsezo cha hypoglycemia, makamaka usiku. Glargine yatsopano ya Sanofi ikupita patsogolo kwambiri. Zovomerezeka mpaka maola 35. Kugwiritsa ntchito poyang'anira glycemic.Sitha kugwiritsidwa ntchito pochiza matenda ashuga a ketoacidosis. Ndikosayenera kutenga ana ndi amayi apakati. Ndi matenda a impso ndi chiwindi, sizinasankhidwe.Kuyambira 2200
ProtafanImakhala ndi kutalika kwa nthawi yayitali. Amawerengera amayi omwe ali ndi pakati. Oyenera T1DM ndi T2DM. Amathandizira magawo a shuga m'magazi bwino.Zingayambitse kuyabwa pakhungu, redness, kutupa.Kuyambira 800
RosinsulinOtetezeka kwa mkaka ndi pakati. Mitundu itatu imapangidwa (P, C ndi M), yomwe imasiyanitsidwa ndi kuthamanga ndi nthawi yowonekera.Sioyenera aliyense, zonse zimatengera umunthu wake.Kuyambira 1100
TresibaChofunikira chachikulu ndi insulin degludec. Momwe amachepetsa kwambiri zochitika za hypoglycemia. Kusunga shuga wokhazikika tsiku lonse. Zovomerezeka kwa maola opitilira 40.Osakhala yoyenera kuthandizira ana, kunyambita ndi amayi apakati. Ochepa omwe amagwiritsidwa ntchito pochita. Zimayambitsa zovuta.Kuyambira 8000.

Malinga ndi akatswiri, ngati pambuyo pa kumwa kamodzi pa insulini palibe kusintha kosintha kwa shuga, ndikofunika kupatsidwa analog yochepa.

Levemir ndi wabwino kwambiri pochiza odwala matenda ashuga. Chida ichi chamakono komanso chotsimikiziridwa chikuthandizira kuchepa kwamwazi wamagazi.

Irina, wazaka 27, Moscow.

"Poyamba, ndidakana kukana Levemir.Ndani akufuna kutenga insulin kapena kulemera kowonjezera? Dotolo adanditsimikizira kuti sizotheka kuchira kwa iye ndipo sanayambitse kudalira. Anandiika 6 ma insulin kamodzi patsiku.

Koma zodandaula sizinathe. Kodi nditha kubereka mwana wathanzi, kodi padzakhala mavuto ndi kukula kwake? Mankhwalawa ndi okwera mtengo. Sindinazindikire mavuto aliwonse kunyumba; mwanayo adabadwa mosatekeseka. Nditabereka, ndinasiya jakisoni wa Levemir;

Chifukwa chake ndimalimbikitsa. ”

Eugene, wazaka 43, Moscow.

“Ndili ndi matenda ashuga 1 kuyambira ndili mwana. M'mbuyomu, kunali kofunikira kutola insulini mu syringe kuchokera ku ampoules, kuyeza mayunitsi ndikudzibaya nokha. Ma syringe amakono omwe ali ndi cartulin ya insulin ndiwosavuta, ali ndi mfundo yoti azitha kuyika manambala. Mankhwalawa amachita mosamalitsa malinga ndi malangizo, ndimapita nawo maulendo azamalonda, zonse ndizopambana. Ndikukulangizani. ”

Huseyn, wazaka 40, Moscow.

Kwa nthawi yayitali sindimatha kuthana ndi vuto la shuga m'mawa. Adasinthira ku Levemir. Gawani majakisoni 4, omwe ndimachita kwa maola 24. Ndimatsatira zakudya zamafuta ochepa. Patatha mwezi umodzi kusinthaku kupita ku boma latsopano, shuga sanathenso. Tithokoze opanga. ”

Levemir Flexpen ndi Penfil - malangizo, ntchito, mayendedwe, ndemanga

Levemir ndi mankhwala a hypoglycemic omwe ali ofanana mu kapangidwe kake ka mankhwala ndi zochita kwa insulin yaumunthu. Mankhwalawa ali m'gulu la anthu omwe amapanganso insulin.

Levemir Flexpen ndi cholembera cha insulin chapadera ndi chothandizira. Chifukwa cha izo, insulin imatha kutumizidwa kuchokera ku 1 unit mpaka 60 unit. Kusintha kwa Mlingo kumapezeka mgulu limodzi.

Pa mashelu apachipatala mungapeze Levemir Penfill ndi Levemir Flekspen. Kodi amasiyana bwanji wina ndi mnzake? Kapangidwe konse ndi mlingo, njira ya makonzedwe ali chimodzimodzi. Kusiyana pakati pa oyimilira kuli pakumasulidwa. Levemir Penfill ndi makatoni omwe angathe kusintha m'malo mwa cholembera. Ndipo Levemir Flekspen ndi cholembera chimbale chotayika chomwe chili ndi makatoni omangidwa mkati.

Levemir amagwiritsidwa ntchito kuti azisunga insulin yamagazi kwambiri, mosasamala zakudya.

Chofunikira chachikulu pa mankhwalawa ndi kunyansidwa ndi insulin. Ndi insulin yamaumboni yaumunthu yomwe imapangidwa pogwiritsa ntchito chibadwa cha bakiteriya ya Saccharomyces cerevisiae. Mlingo wa yogwira 1 mg wa yankho ndi 100 IU kapena 14.2 mg. Komanso, 1 unit ya recombinant insulin Levemir ndi ofanana 1 unit ya insulin ya munthu.

Zowonjezera zina zimathandizira. Gawo lililonse limayang'anira ntchito zina. Amakhazikitsa kapangidwe ka yankho, amapereka zofunika zapadera zamankhwala, ndikuwonjezera nthawi yosungirako ndi moyo wa alumali.

Komanso, zinthuzi zimathandizira kukonza komanso kukonza ma pharmacokinetics ndi ma pharmacodynamics a kantheya kogwira ntchito: amasintha bioavailability, kupangika kwa minofu, kuchepetsa kumangiriza kwa mapuloteni amwazi, kuwongolera kagayidwe kazinthu ndi njira zina zochotsera.

Zinthu zina zotsatirazi zimaphatikizidwa ndi yankho la mankhwalawa:

  • Glycerol - 16 mg,
  • Metacresol - 2.06 mg,
  • Zink acetate - 65.4 mcg,
  • Phenol - 1,8 mg
  • Sodium Chloride - 1.17 mg
  • Hydrochloric acid - q.s.,
  • Hydrophosphate dihydrate - 0,89 mg,
  • Madzi a jakisoni - mpaka 1 ml.

Cholembera chilichonse kapena cartridge imakhala ndi 3 ml ya yankho kapena 300 IU ya insulin.

Mankhwala

Levemir insulin ndi mawonekedwe a insulin yaumunthu yokhala ndi nthawi yayitali, yosanja mawonekedwe. Kuchitidwa kwa mtundu wosachedwa kumachitika chifukwa cha kuphatikiza kwakukulu komwe kumayenderana ndi ma mamolekyulu a mankhwala.

Amanganso ena kumapuloteni m'dera lamatumbo. Zonsezi zimachitika pamalo operekera jakisoni, kotero kuti insulin ya insulin imalowera m'magazi pang'onopang'ono.

Ndipo zimakhala zofunikira zimalandira mlingo wofunikira pambuyo pake ndi ena oimira insulin.

Njira izi zimathandizira kugawa mankhwalawa, omwe amathandiza kuyamwa komanso chidziwitso cha kagayidwe.

Akuluakulu analimbikitsa mlingo wa 0,2-0.4 U / kg umafika hafu ya mphamvu pambuyo maola atatu. Nthawi zina, nthawi imeneyi imatha kuchedwa mpaka maola 14.

Pharmacokinetics

Mankhwalawa amafikira kuchuluka kwake m'magazi pambuyo pakupita kwa maola 6-8.

Kuphatikiza kosalekeza kwa mankhwalawa kumatheka ndi kuwongolera kawiri patsiku ndipo kumakhazikika pambuyo pa jakisoni 3.

Mosiyana ndi insulin ina yoyambira, kusiyanasiyana kwa mayamwidwe ndi magawidwe kumakhala kosadalira pa umunthu wake. Komanso, palibe kudalira mtundu ndi mtundu wa akazi.

Kafukufuku akuwonetsa kuti Levemir insulin kwenikweni sikugwirizana ndi mapuloteni, ndipo zochuluka za mankhwalawa zimazungulira m'madzi am'magazi (kuchuluka kwa mankhwalawa kufikira 0,1 l / kg). Insulin yolimbitsa thupi mu chiwindi ndi kuchotsedwa kwa ma metabolites osagwira.

Hafu ya moyo imatsimikiziridwa ndi kudalira nthawi yonyowetsedwa m'magazi pambuyo pa kayendetsedwe ka subcutaneous. Pafupifupi theka la moyo wodalira mlingo ndi maola 6-7.

Zizindikiro ndi contraindication

Chizindikiro chokhacho chogwiritsira ntchito Levemir ndikuzindikira kwa matenda a shuga omwe amadalira odwala a shuga ndi ana opitirira zaka 2.

Contraindled pakumagwiritsa ntchito mankhwalawa ndi kupezeka kwa tsankho kwa chinthu chachikulu chothandizira ndi zigawo zothandizira.

Komanso, kudya kumapangidwa pakati pa ana osaposa zaka ziwiri chifukwa chosowa maphunziro azachipatala m'gulu la odwala.

Malangizo ogwiritsira ntchito

Insulin Levemir yemwe amagwira ntchito kwa nthawi yayitali amatengedwa 1 kapena 2 kawiri pa tsiku ngati mankhwala oyambira a bolus. Kuphatikiza apo, imodzi mwamwa imathandizidwa kwambiri madzulo asanagone kapena chakudya chamadzulo. Izi zimalepheretsanso kugona kwa hypoglycemia usiku.

Mlingo amasankhidwa ndi dokotala payekhapayekha kwa wodwala aliyense. Mlingo ndi pafupipafupi wa makonzedwe zimadalira thupi la munthu, mfundo za zakudya, kuchuluka kwa shuga, kuopsa kwa matendawa komanso momwe wodwala amayendera tsiku ndi tsiku. Komanso, chithandizo choyambirira sichitha kusankhidwa kamodzi. Kusinthasintha kulikonse kwa mfundo zomwe zili pamwambapa kuyenera kudziwitsidwa kwa dokotala, ndipo mlingo wonse watsiku ndi tsiku uyenera kufotokozedwanso.

Komanso, kugwiritsa ntchito mankhwala osokoneza bongo kumasintha ndikukula kwa matenda aliwonse oyanjana kapena kufunikira kwa kuchitapo kanthu.

Sitikulimbikitsidwa kuti musinthe mosiyanasiyana mankhwalawa, ndikulilumphira, kusintha pafupipafupi, motero pali mwayi waukulu wokhala ndi hypoglycemic kapena hyperglycemic coma komanso kuchulukitsa kwa neuropathy ndi retinopathy.

Levemir angagwiritsidwe ntchito ngati monotherapy, komanso kuphatikiza kuyambitsa ma insulin apafupi kapena mankhwala a pakamwa a hypoglycemic. Pali chithandizo chokwanira, kuchuluka kwa kuvomerezeka ndi nthawi 1.

Mulingo woyenera ndi magawo 10 kapena 0,1 - 0,2 ma kilogalamu.

Nthawi yoyang'anira masana imatsimikiziridwa ndi wodwala iyemwini, monga momwe iyenera iye. Koma tsiku lililonse muyenera kubaya mankhwala mosamala nthawi yomweyo.

Levemir: malangizo ogwiritsira ntchito. Momwe mungasankhire mlingo. Ndemanga

Insulin Levemir (detemir): phunzirani zonse zomwe mukufuna. Pansipa mupeza malangizo atsatanetsatane ogwiritsira ntchito olembedwa mchilankhulo. Dziwani:

Levemir ndi insulin yowonjezera (basal), yomwe imapangidwa ndi kampani yotchuka komanso yolemekezeka yapadziko lonse Novo Nordisk. Mankhwalawa agwiritsidwa ntchito kuyambira m'ma 2000s. Anakwanitsa kutchuka pakati pa odwala matenda ashuga, ngakhale insulin Lantus ili ndi gawo lalikulu pamsika. Werengani ndemanga zenizeni za odwala omwe ali ndi matenda amtundu wa 2 komanso matenda amitundu iwiri, komanso zomwe ana angagwiritse ntchito.

Komanso phunzirani zamankhwala othandizira omwe amasunga magazi anu kukhala 3.9-5,5 mmol / L khola maola 24 patsiku, monga momwe mungakhalire ndi anthu athanzi.Dongosolo la Dr. Bernstein, amene akhala ndi matenda ashuga kwa zaka zopitilira 70, amalola akuluakulu ndi ana odwala matenda ashuga kudziteteza ku zovuta zowopsa.

Long insulin levemir: Nkhani zatsatanetsatane

Chidwi chachikulu chimaperekedwa polamulira matenda ashuga. Levemir ndi mankhwala osankhidwa kwa amayi apakati omwe ali ndi shuga wambiri. Kafukufuku wovuta watsimikizira chitetezo chake komanso kugwira ntchito bwino kwa amayi oyembekezera, komanso kwa ana kuyambira zaka ziwiri.

Kumbukirani kuti insulin yowonongeka imakhala yowoneka bwino kwambiri. Ubwino wa mankhwalawa sungadziwike ndi maonekedwe ake. Chifukwa chake, sizoyenera kugula Levemir yokhala m'manja, ndikulengeza mwachinsinsi. Gulani mumasitolo akuluakulu odziwika omwe antchito ake amadziwa malamulo osungira ndipo si aulesi kwambiri kuti athe kutsatira.

Malangizo ogwiritsira ntchito

Zotsatira za pharmacologicalMonga mitundu ina ya insulin, Levemir amachepetsa shuga m'magazi, ndikupangitsa maselo a chiwindi ndi minofu kulowa glucose. Mankhwalawa amathandizanso kuphatikiza mapuloteni komanso kusintha kwa glucose kukhala mafuta. Amapangidwira kuti azilipira shuga asala kudya, koma sizithandiza kuwonjezera shuga pambuyo kudya. Ngati ndi kotheka, gwiritsani ntchito kukonzekera kwakanthawi kochepa kapena kwa ultrashort kuwonjezera pa insulin yayitali.
PharmacokineticsJekeseni aliyense wa mankhwalawa amatenga nthawi yayitali kuposa jakisoni wa sing'anga wa insulin Protafan. Chida ichi chilibe tanthauzo lenileni. Malangizo a boma akuti Levemir amagwira ntchito bwino kwambiri kuposa Lantus, yemwe ali mpikisano wake wamkulu. Komabe, opanga a Lantus insulin sangavomereze izi :). Mulimonsemo, mankhwala atsopano a Tresiba amatsitsa shuga m'magayidwe a shuga kwa nthawi yayitali (mpaka maola 42) komanso bwino kuposa Levemir ndi Lantus.
Zizindikiro zogwiritsidwa ntchitoType 1 and Type 2abetes mellitus, omwe amafunika jakisoni wa insulin kuti amalipire chindalama chokwanira cha matenda a shuga. Itha kuperekedwa kwa ana kuyambira zaka 2, ndipo makamaka kwa achikulire ndi okalamba. Werengani nkhani yoti: “Chithandizo cha Matenda a shuga Aakulu Kwa Akuluakulu ndi Ana” kapena “Insulin ya Matenda A 2”. Levemir ndi mankhwala osankhidwa kwa ana odwala matenda ashuga omwe amafuna Mlingo wochepa wochepera 1-2 mayunitsi. Chifukwa imatha kuchepetsedwa, mosiyana ndi insulin Lantus, Tujeo ndi Tresiba.

Mukabayidwa jekeseni wa Levemir, monga mtundu wina uliwonse wa insulin, muyenera kutsatira zakudya.

Mtundu wa matenda a shuga a 2 Mtundu woyamba wa shuga Zakudya tebulo No. 9 Masamba a sabata: Zitsanzo

ContraindicationThupi lawo siligwirizana ndi insulin detemir kapena othandizira zigawo zikuluzikulu za jakisoni. Palibe zambiri zochokera ku maphunziro azachipatala a mankhwalawa okhudzana ndi ana odwala matenda ashuga osakwana zaka 2. Komabe, palibe deta yotereyi yopikisana ndi mtundu wa insulin mwina. Chifukwa chake Levemir amagwiritsidwa ntchito mosavomerezeka kuti amalipirire matenda a shuga ngakhale kwa ana aang'ono kwambiri. Komanso, ikhoza kuchepetsedwa.
Malangizo apaderaOnani nkhani yofotokoza momwe matenda opatsirana, kupsinjika kwamphamvu komanso kosatha, ndi nyengo zimakhudzira zosowa za insulin za odwala matenda ashuga. Werengani momwe mungaphatikizire shuga ndi insulin ndi mowa. Musakhale aulesi kubaya Levemir 2 kawiri pa tsiku, osadziika malire ndi jakisoni imodzi patsiku. Insulin iyi ikhoza kuchepetsedwa ngati pakufunika, mosiyana ndi kukonzekera Lantus, Tujeo ndi Tresiba.

Sonyezani shuga yanu kapena sankhani jenda kuti mulimbikitsidwe

MlingoPhunzirani nkhani ya "Kuwerengera Mlingo Wamtundu wa Insulin Yambiri ya Jakisoni Usiku ndi M'mawa". Sankhani mlingo woyenera, komanso ndandanda ya jakisoni payekhapayekha, malinga ndi zomwe amapezeka ndi shuga kwa masiku angapo. Musagwiritse ntchito malingaliro oyambira kuti ayambire 10 PIECES kapena 0,0-0.2 PIECES / kg. Kwa odwala matenda ashuga achikulire omwe amatsata zakudya zama carb ochepa, izi ndizokwera kwambiri. Ndipo makamaka kwa ana. Werengani werengani zomwe zalembedwa kuti: “Mankhwala a insulin.
Zotsatira zoyipaChoyipa chowopsa ndi shuga m'magazi (hypoglycemia).Mvetsetsani zomwe izi zikuonetsa, momwe mungathandizire wodwala. M'malo jakisoni pakhoza kukhala redness ndi kuyabwa. Zotsatira zoyipa kwambiri za thupi sizimachitika. Ngati chiwonetserochi chikuphwanya, malo ena obayira angayambire lipohypertrophy.

Anthu ambiri odwala matenda ashuga omwe amathandizidwa ndi insulin sawona kuti ndizotheka kupewa kukhala ndi vuto la hypoglycemia. M'malo mwake, izi siziri choncho. Mutha kusunga shuga wokhazikika ngakhale ndi matenda oopsa a autoimmune. Ndipo makamaka, ndi matenda a shuga a 2 ochepa. Palibe chifukwa chakuwonjezera kuchuluka kwa shuga m'magazi anu kuti mudzilimbitse nokha motsutsana ndi hypoglycemia yoopsa. Onerani kanema pomwe Dr. Bernstein akufotokoza nkhaniyi.

Kuchita ndi mankhwala enaMankhwala omwe amatha kupititsa patsogolo zotsatira za insulini amaphatikizapo mapiritsi ochepetsa shuga, komanso ACE inhibitors, disopyramides, fibrate, fluoxetine, MAO inhibitors, pentoxifylline, propoxyphene, salicylates ndi sulfonamides. Amatha kufooketsa mphamvu ya jakisoni: danazol, diazoxide, diuretics, glucagon, isoniazid, estrogens, gestagens, zotengera za phenothiazine, somatotropin, epinephrine (adrenaline), salbutamol, terbutaline ndi mahomoni a chithokomiro, protease inhibitors, olanzapine, Lankhulani ndi dokotala wanu za mankhwala onse omwe mumamwa!
BongoNgati mlingo womwe waperekedwa ndiwokwera kwambiri kwa wodwalayo, hypoglycemia imatha kuchitika, mutakhala ndi chikumbumtima chodandaula. Zotsatira zake ndikuwonongeka kwa ubongo kosasinthika, ngakhale kufa. Ndiwosowa, pokhapokha ngati pali mankhwala osokoneza bongo mwadala. Kwa Levemir ndi mitundu ina yayitali ya insulini, chiwopsezo ndichochepa kwambiri, koma osati ziro. Werengani apa momwe mungaperekere chithandizo chamankhwala kwa wodwala.
Kutulutsa FomuLevemir amawoneka ngati yankho lomveka, lopanda utoto. Wogulitsidwa mumak cartridge atatu. Makatoni awa amatha kukhazikitsidwa m'mapensulo otayidwa a FlexPen ndi gawo la 1 unit. Mankhwala opanda cholembera amatchedwa Penfill.
Migwirizano ndi magwiritsidwe akusungidwaMonga mitundu ina ya insulin, mankhwalawa Levemir ndi osalimba, amatha kuwonongeka mosavuta. Kuti mupewe izi, phunzirani malamulo osungira ndikuwatsata mosamala. Alumali moyo wa cartridge mutatsegulidwa ndi masabata 6. Mankhwalawa, omwe sanayambe kugwiritsidwa ntchito, amatha kusungidwa m'firiji kwa zaka 2.5. Osamawuma! Pewani kufikira ana.
KupangaChomwe chimagwira ndi insulin. Othandizira - glycerol, phenol, metacresol, zinc acetate, sodium hydrogen phosphate dihydrate, sodium chloride, hydrochloric acid kapena sodium hydroxide, madzi a jekeseni.

Onani pansipa kuti mumve zambiri.

Kodi levemir ndi insulini ya chochita? Kodi ndizitali kapena zazifupi?

Levemir ndi insulin wa nthawi yayitali. Mlingo uliwonse womwe umaperekedwa umachepetsa shuga mkati mwa maola 18-24. Komabe, odwala matenda ashuga omwe amatsata zakudya zama carb ochepa amafunika Mlingo wochepetsetsa, 2-8 nthawi yotsika kuposa wamba.

Pogwiritsa ntchito mankhwalawa, mphamvu ya mankhwalawa imatha mofulumira, mkati mwa maola 10-16. Mosiyana ndi wastani insulin Protafan, Levemir alibe chiwonetsero chokwanira kuchitapo kanthu.

Samalani ndi mankhwala atsopano a Tresib, omwe amakhala nthawi yayitali, mpaka maola 42, komanso bwino.

Levemir si inshuwaransi yayifupi. Sikoyenera malo omwe muyenera kuthana ndi shuga msanga. Komanso, siyenera kunenedwa musanadye chakudya kuti mugwirizane ndi chakudya chomwe odwala matenda ashuga akukonzekera kudya. Pazifukwa izi, kukonzekera kwakanthawi kapena ultrashort kumagwiritsidwa ntchito. Werengani nkhani yakuti “Mitundu ya Insulin ndi Zotsatira Zawo” mwatsatanetsatane.

Onerani kanema wa Dr. Bernstein. Dziwani chifukwa chake Levemir ali bwino kuposa Lantus. Mvetsetsani kangati patsiku muyenera kulidulira ilo komanso nthawi yanji. Onani kuti mukusunga insulini yanu molondola kuti isawonongeke.

Momwe mungasankhire mlingo?

Mlingo wa Levemir ndi mitundu ina yonse ya insulin uyenera kusankhidwa payekhapayekha.Kwa odwala matenda ashuga akuluakulu, pali malingaliro oyambira kuti ayambe ndi 10 PIECES kapena 0,1-0.2 PIECES / kg.

Komabe, kwa odwala omwe amatsata zakudya zama carb otsika kwambiri, mankhwalawa azikhala okwera kwambiri. Onani shuga wanu wamagazi masiku angapo. Sankhani mulingo woyenera wa insulin pogwiritsa ntchito zomwe mwalandira.

Werengani zambiri mu nkhani "Kuwerengera Mlingo wa insulin yayitali usiku ndi m'mawa."

Kodi mankhwalawa amafunika kuti alowetse ndani mwa mwana wazaka 3?

Zimatengera zakudya zamtundu wanji mwana wodwala matenda ashuga. Ngati adasinthidwa kudya zakudya zama carb ochepa, ndiye kuti Mlingo wochepetsetsa kwambiri, ngati homeopathic, ungafunike.

Mwinanso, muyenera kulowa ku Levemir m'mawa ndi madzulo muzinthu zosaposa 1 unit. Mutha kuyamba ndi mayunitsi 0,25. Kuti mupeze jekeseni yotsika bwino, ndikofunikira kuthira njira yofayira jakisoni.

Werengani zambiri za izo apa.

Pakazizira, poizoni wa chakudya ndi matenda ena opatsirana, Mlingo wa insulin uyenera kuchuluka nthawi 1.5. Chonde dziwani kuti kukonzekera kwa Lantus, Tujeo ndi Tresiba sikungathe kuchepetsedwa.

Chifukwa chake, kwa ana aang'ono a mitundu yayitali ya insulin, ndi Levemir ndi Protafan yekhayo amene atsalira. Phunzirani nkhani ya “Matenda a Ana A shuga.”

Phunzirani momwe mungatalikitsire nthawi yanu ya tchuthi ndikukhazikitsa mtundu wabwino wama glucose.

Mitundu ya insulini: Momwe mungasankhire mankhwala a insulin yayitali usiku ndi m'mawa Muwerengera kuchuluka kwa insulin musanadye chakudya

Momwe mungasinthire Levemir? Kangati patsiku?

Levemir sikokwanira kumangodula kamodzi patsiku. Iyenera kuperekedwa kawiri pa tsiku - m'mawa ndi usiku. Kuphatikiza apo, zochita zamankhwala a madzulo nthawi zambiri sizikhala zokwanira usiku wonse. Chifukwa cha izi, odwala matenda ashuga amatha kukhala ndi zovuta zam'mawa m'mimba yopanda kanthu. Werengani nkhani yoti "Shuga pamimba yopanda kanthu m'mawa: momwe mungabwezeretsere zodabwitsa". Komanso werengani za "insulin management: momwe ndi momwe mungabayitsire".

Kodi mankhwalawa angafanane ndi Protafan?

Levemir ndi wabwino kwambiri kuposa Protafan. Majekeseni a insulin a Protafan satenga nthawi yayitali, makamaka ngati milingo yotsika. Mankhwalawa amakhala ndi puloteni wa nyama, zomwe nthawi zambiri zimayambitsa matupi awo.

Ndikwabwino kukana kugwiritsa ntchito protafan insulin. Ngakhale mankhwalawa akaperekedwa kwaulere, ndipo mitundu ina ya insulin yowonjezera idzayenera kugulidwa ndi ndalama. Pitani ku Levemir, Lantus kapena Tresiba.

Werengani zambiri mu nkhani "Mitundu ya Insulin ndi Zotsatira Zawo".

Zomwe zili bwino: Levemir kapena Humulin NPH?

Humulin NPH ndi insulin yochita ngati sing'anga, ngati Protafan. NPH ndi protamine ya Hagedorn yosaloledwa, mapuloteni omwewo omwe nthawi zambiri amayambitsa ziwengo. zimachitika. Humulin NPH sayenera kugwiritsidwa ntchito pazifukwa zofanana ndi Protafan.

Levemir Penfill ndi Flekspen: Kusiyana kwake ndi kotani?

Flekspen ndi cholembera chimbale momwe mavekitala a inshuwaransi ya Levemir amaikiramo.

Penfill ndi mankhwala a Levemir omwe amagulitsidwa popanda zolembera kuti mugwiritse ntchito syringes yokhazikika ya insulin. Ma cholembera a Flexspen ali ndi gawo la 1 unit.

Izi zitha kukhala zosokoneza mankhwalawa a shuga kwa ana omwe amafunikira kuchuluka. Zikatero, ndikofunika kupeza ndikugwiritsa ntchito Penfill.

Levemir alibe ma analogu otsika mtengo. Chifukwa mawonekedwe ake amatetezedwa ndi patent yomwe kuvomerezeka kwake sikunathe. Pali mitundu ingapo yofanana ya insulin yayitali kuchokera kwa opanga ena. Awa ndi mankhwala Lantus, Tujeo ndi Tresiba.

Mutha kuphunzira mwatsatanetsatane nkhani iliyonse. Komabe, mankhwalawa onse siotsika mtengo. Insulin-average insulin, monga Protafan, imakhala yotsika mtengo. Komabe, zili ndi zolakwika zazikulu chifukwa chake Dr. Bernstein ndi tsamba la odwala endocrin.

com sikulimbikitsa kugwiritsa ntchito.

Levemir kapena Lantus: ndi insulin iti bwino?

Yankho lachilendo la funsoli laperekedwa munkhaniyi ya insulin Lantus.Ngati Levemir kapena Lantus akukwiyirani, pitilizani kugwiritsa ntchito. Musasinthe mankhwala amitundu ina pokhapokha pakufunika.

Ngati mukukonzekera kuyamba kubayitsa insulin yayitali, ndiye yesetsani Levemir. Insulin yatsopano ya Treshiba ndiyabwino kuposa Levemir ndi Lantus, chifukwa imatenga nthawi yayitali komanso bwino.

Komabe, zimawononga pafupifupi katatu katatu.

Levemir pa mimba

Kafukufuku wamkulu wazachipatala adachitidwa omwe adatsimikizira chitetezo ndi kuyendetsa bwino kwa kayendetsedwe ka Levemir pa nthawi yapakati.

Mitundu yampikisano ya insulin Lantus, Tujeo ndi Tresiba sangadzitame chifukwa cha umboni wabwino wotetezedwa.

Ndikofunika kuti mayi woyembekezera yemwe ali ndi shuga wambiri amvetsetse momwe angawerengere Mlingo woyenera.

Insulin siyowopsa kwa mayi kapena kwa mwana wosabadwayo, malinga ngati mankhwalawo asankhidwa molondola. Matenda a shuga oyembekezera, ngati atasiyidwa, amatha kubweretsa mavuto akulu. Chifukwa chake, lembani molimba mtima Levemir ngati dokotala wakuuzani kuti muchite izi. Yesani kuchita popanda kulandira insulin, kutsatira zakudya zabwino. Werengani nkhani zakuti “Amayi Azipakati” ndi “Gestational Diabetes” kuti mumve zambiri.

Levemir wakhala akugwiritsidwa ntchito kuwongolera matenda a shuga a 2 ndikulemba mtundu 1 kuyambira m'ma 2000s. Ngakhale mankhwalawa ali ndi mafani ocheperako kuposa a Lantus, ndemanga zokwanira zasonkhana pazaka zambiri. Ambiri mwaiwo ndi abwino. Odwala amati insulin imachepetsa shuga m'magazi. Nthawi yomweyo, chiopsezo cha hypoglycemia ndichochepa kwambiri.

Gawo lalikulu la ndemanga zalembedwa ndi azimayi omwe amagwiritsa ntchito Levemir pa nthawi yoyembekezera kuti athe kuthana ndi matenda ashuga. Kwenikweni, odwala awa amakhutira ndi mankhwalawo. Sichosokoneza, jakisoni wobala mwana atatha kuthetsedwa popanda mavuto. Kulondola ndikofunikira kuti musapange cholakwika ndi muyezo, koma ndi kukonzekera kwina kwa insulin ndi chimodzimodzi.

Malinga ndi odwala, chododometsa chachikulu ndikuti cartridge yoyambira iyenera kugwiritsidwa ntchito mkati mwa masiku 30. Ino ndi nthawi yochepa kwambiri. Nthawi zambiri mumayenera kutaya ndalama zonse zosagwiritsidwa ntchito, ndipo pambuyo pake, ndalama zawalipira. Koma mankhwala onse opikisana ali ndi vuto lomweli. Ndemanga za odwala matenda ashuga zimatsimikizira kuti Levemir ndiwopambana ndi pafupifupi insulin Protafan pankhani zonse zofunika.

Insulin LEVEMIR: ndemanga, malangizo, mtengo

Levemir Flexpen ndi analogue of insulin yamunthu ndipo imakhala ndi hypoglycemic. Levemir imapangidwa ndikuwonjezera kwa DNA yomwe ikubwerekanso pogwiritsa ntchito Saccharomyces cerevisiae.

Ndi osungunuka basalle a insulin yaumunthu yokhala ndi mphamvu yayitali komanso mawonekedwe a pang'onopang'ono pochita, osasinthika kwambiri poyerekeza ndi insulin glargine ndi isofan-insulin.

Kuchitikira kwakanthawi kwa mankhwalawa kumachitika chifukwa chakuti ma molekyulu a insulir amatha kudziwonetseratu pawebusayiti, komanso kumangiriza ku albumin pophatikiza ndi unyolo wamafuta acid.

Dermul ya Detemir imagwira zotumphukira zamafupipafupi pang'onopang'ono kuposa isofan-insulin. Kuphatikizika kwa njira zogwiritsidwira ntchito masiku ano kumathandizanso kuti mbiri ya Levemir Penfill ichitike kuposa isofan-insulin.

Mukamangirira ma receptor enieni pa cytoplasmic membrane wa insulin, insulin imapanga mawonekedwe apadera omwe amalimbikitsa kapangidwe kazinthu zingapo zofunika za ma enzymes mkati mwa maselo, monga hexokinase, glycogen synthetase, pyruvate kinase ndi ena.

Chizindikiro chachikulu pakugwiritsa ntchito Levemir Flexpen ndi matenda ashuga.

Contraindication

Insulin sikuyenera kutumikiridwa ndi chidwi chowonjezeka cha munthu kuti awonerere insulini kapena chinthu china chilichonse chomwe ndi gawo lazopangidwe.

Levemir Flexpen sagwiritsidwa ntchito mwa ana ochepera zaka zisanu ndi chimodzi, chifukwa palibe maphunziro azachipatala omwe adachitidwa pa ana aang'ono.

Mlingo ndi makonzedwe

Kwa Levemir Flexpen, njira yotsogoza imagwiritsidwa ntchito. Mlingo ndi kuchuluka kwa jakisoni zimatsimikiziridwa payekhapayekha kwa munthu aliyense payekha.

Potumiza mankhwala limodzi ndi othandizira kuchepetsa shuga pamlomo, pakulimbikitsidwa kuti mugwiritse ntchito kamodzi patsiku pa mlingo wa 0.1-0.2 U / kg kapena 10 U.

Ngati mankhwalawa amagwiritsidwa ntchito ngati gawo la regimen ya maziko-a bolus, ndiye kuti amawayikidwa kutengera zosowa za wodwala 1 kapena 2 pa tsiku. Ngati munthu akufunika kugwiritsa ntchito insulin kawiri kuti akhalebe ndi shuga wokwanira, ndiye kuti kumwa kwamadzulo kumatha kutumikiridwa panthawi ya chakudya chamadzulo kapena pogona, kapena pambuyo pa maola 12 kutacha.

Zingwe za Levemir Penfill zimabayidwa pang'onopang'ono m'khosi, kunja kwamimba khoma kapena ntchafu, tsatanetsatane wa momwe jekeseni wa insulin angapangidwire patsamba lathu. Ngakhale jakisoni utachitidwa mbali yomweyo ya thupi, tsamba la jakisidwe liyenera kusinthidwa.

Kusintha kwa Mlingo

Odwala mu ukalamba kapena pamaso pa aimpso kapena kwa chiwindi, kusintha kwa mankhwalawa kuyenera kuchitika, monga insulin ina. Mtengo sasintha kuchokera pamenepa.

Mlingo wa detemir insulin uyenera kusankhidwa payekhapayekha popenyerera shuga m'magazi.

Komanso, kuwunikiridwa kwa mlingo ndikofunikira ndikuwonjezera zolimbitsa thupi kwa wodwalayo, kupezeka kwa matenda oyanjana kapena kusintha kwa zakudya zake.

Kusintha kuchokera kukonzekera kwina kwa insulin

Ngati pakufunika kusamutsa wodwala kuchokera kwa insulin yayitali kapena mankhwala osokoneza bongo apakati pa Levemir Flexpen, ndiye kuti kusintha kosintha kwakanthawi kokhazikika, komanso kusintha kwa mlingo, kungafunike.

Monga kugwiritsa ntchito mankhwala enanso ofananawo, ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magazi poyisintha nokha komanso pakatha milungu ingapo yoyambirira yogwiritsa ntchito mankhwalawa.

Nthawi zina, concomitant hypoglycemic Therapy iyeneranso kuwunikiridwa, mwachitsanzo, mankhwala a pakamwa pakamwa kapena mlingo komanso nthawi ya makonzedwe a insulin yokonzekera.

Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere

Palibe zambiri zakuchipatala zomwe zimagwiritsidwa ntchito ndi Levemir Flexpen panthawi yobereka komanso kuyamwitsa. Pophunzira ntchito yachilengedwe mu nyama, palibe kusiyana pakati pa embryotooticity ndi teratogenicity pakati pa insulin ya insulin ndi insulin.

Ngati mayi wapezeka ndi matenda a shuga, kuwunika mosamala ndikofunikira pakukonzekera komanso nthawi yonse ya bere.

Mu trimester yoyamba, nthawi zambiri kufunikira kwa insulin kumachepa, ndipo pambuyo pake kumawonjezeka. Pambuyo pobadwa mwana, nthawi zambiri kufunikira kwa timadzi timeneti kumabwera mwachangu pamlingo woyambirira womwe unali asanakhale ndi pakati.

Pa yoyamwitsa, mkazi angafunike kusintha zakudya zake ndi mlingo wa insulin.

Zotsatira zoyipa

Monga lamulo, mavuto omwe amagwiritsidwa ntchito mwa anthu omwe amagwiritsidwa ntchito ndi mankhwala a Levemir Flexpen amadalira kwambiri mankhwalawa ndipo ndi chifukwa cha insulin.

Zotsatira zoyipa kwambiri ndi hypoglycemia. Zimachitika ngati milingo yayikulu kwambiri ya mankhwalawa imaperekedwa yomwe imaposa kufunika kwachilengedwe kwa insulin.

Kafukufuku wachipatala awonetsa kuti pafupifupi 6% ya odwala omwe amathandizidwa ndi Levemir Flexpen amayamba kukhala ndi hypoglycemia wothandizidwa ndi anthu ena.

Zomwe zimachitika pakukhazikitsidwa kwa mankhwalawa pamalo a jakisoni pogwiritsa ntchito Levemir Flexpen ndizofala kwambiri pochiritsidwa ndi insulin ya anthu. Izi zimawonetsedwa ndi redness, kutupa, kutupa ndi kuyabwa, kuphulika pamalowo jekeseni.

Nthawi zambiri, machitidwe oterewa sakutchulidwa ndipo amakhalapo kwakanthawi (amazimiririka ndikumalandira mankhwala kwa masiku angapo kapena masabata).

Kukula kwa zotsatira zoyipa mwa odwala omwe amathandizidwa ndi mankhwalawa amapezeka pafupifupi 12% ya milandu. Zotsatira zonse zoyipa zomwe zimachitika chifukwa cha mankhwala a Levemir Flexpen amagawidwa m'magulu otsatirawa:

  1. Matenda a metabolism komanso zakudya.

Nthawi zambiri, hypoglycemia imachitika, itakhala ndi zizindikiro zotsatirazi:

  • thukuta lozizira
  • kutopa, kutopa, kufooka,
  • kukopa kwa pakhungu
  • kumverera kwa nkhawa
  • mantha kapena kunjenjemera,
  • idachepetsa nthawi yayitali komanso chisokonezo,
  • kumva kwamphamvu njala
  • mutu
  • kuwonongeka kwamawonekedwe
  • kuchuluka kwa mtima.

Mu hypoglycemia yayikulu, wodwalayo atha kuzindikira, amamva kukokana, kusokonezeka kwakanthawi kapena kosasinthika muubongo kungachitike, ndipo zotsatira zake zingachitike.

  1. Zomwe zimachitika jekeseni:
  • redness, kuyabwa ndi kutupa kumachitika kawirikawiri pamalowo. Nthawi zambiri amakhala osakhalitsa ndipo amadutsa ndi kupitiliza mankhwala.
  • lipodystrophy - sizichitika kawirikawiri, zitha kuyamba chifukwa chakuti lamulo losintha jakisoni m'dera lomwelo sililemekezedwa
  • edema imatha kumayambiriro kwa chithandizo cha insulin.

Zonsezi zimachitika nthawi yochepa.

  1. Kusintha kwa chitetezo chathupi - zotupa za pakhungu, ming'oma, ndimomwe zimayambitsa thupi nthawi zina zimatha kuchitika.

Izi ndizotsatira za mphamvu ya hypersensitivity. Zizindikiro zina zimaphatikizira thukuta, angioedema, kuyabwa, mavuto am'mimba, kuvutika kupuma, kutsika kwa magazi, komanso kugunda kwamtima mwachangu.

Kuwonetsedwa kwa generalised hypersensitivity (anaphylactic reaction) kungakhale koopsa kwa moyo wa wodwalayo.

  1. Kuwonongeka kwamawonekedwe - nthawi zina, matenda ashuga a retinopathy kapena kuwonongeka kwakanthawi kumatha kuchitika.

Mimba komanso kuyamwa

Pogwiritsa ntchito Levemir ® FlexPen ® pa nthawi ya pakati, ndikofunikira kuganizira momwe phindu la kugwiritsira ntchito kwake limaposa ngozi zomwe zingachitike.

Imodzi mwazoyeserera zopanda mayeso zomwe zimaphatikizidwa ndi amayi apakati omwe ali ndi matenda a shuga 1, momwe zimakhalira ndi chitetezo cha mankhwala ophatikiza ndi Levemir ® FlexPen ® ndi insulin aspart (azimayi oyembekezera 152) poyerekeza ndi insulin-isofan yophatikizidwa ndi insulin aspart ( Amayi oyembekezera 158), sanawonetse kusiyana pakumvetsetsa konse panthawi ya pakati, pazotsatira za pakati kapena pakukhudzidwa kwa thanzi la mwana wosabadwa ndi wakhanda (onani "Pharmacodynamics", "Pharmacokinetics" )

Zowonjezera pazakuchita bwino komanso chitetezo pamankhwala a Levemir ® FlexPen ® omwe amapezeka mwa azimayi 300 oyembekezera panthawi yogulitsa atagwiritsa ntchito akuwonetsa kusakhalapo kwa zotsatira zoyipa za insulin, zomwe zimayambitsa kusokonezeka kobadwa nako komanso kuwonongeka kwa poyipa.

Kafukufuku wokhudzana ndi kubereka mu nyama sanawonetse kuchuluka kwa mankhwalawa pakubala (onani "Pharmacodynamics", "Pharmacokinetics").

Mwambiri, kuwunika mosamala amayi apakati omwe ali ndi matenda ashuga panthawi yonse yomwe ali ndi pakati, komanso pokonzekera kutenga pakati, ndikofunikira. Kufunika kwa insulini mu nthawi yoyambirira ya mimba nthawi zambiri kumachepa, ndiye kuti mu trimesters yachiwiri ndi yachitatu imachulukirachulukira. Pambuyo pobadwa, kufunikira kwa insulin kumabwereranso msanga momwe kunaliri asanakhale ndi pakati.

Sizikudziwika ngati insulin imalowa mu Detemir mkaka wa m'mawere a anthu.Amaganiziridwa kuti insulir insulini siyikhudzanso ma metabolic a mthupi la akhanda / makanda pakuyamwa, chifukwa ndi gawo la gulu la ma peptides omwe amaswa mosavuta mu ma amino acid m'mimba yamagetsi ndikulowetsedwa ndi thupi.

Mwa amayi nthawi yoyamwitsa, kusintha kwa insulin kungafunike.

Kuchita

Pali mankhwala angapo omwe amakhudza kagayidwe ka glucose.

Kufunika kwa insulin kumatha kuchepa mankhwala amkamwa a hypoglycemic, glucagon-peptide-1 receptor agonists (GLP-1), Ma inhibitors a MAO, osagwiritsa ntchito beta-blockers, ma inhibitors a ACE, salicylates, anabolic steroids ndi sulfonamides.

Zofunikira za insulin zitha kuchuluka njira yolerera ya pakamwa ya mahomoni, thiazide diuretics, corticosteroids, mahomoni a chithokomiro, sympathomimetics, somatropin ndi danazole.

Beta blockers imatha kuvala zizindikiro za hypoglycemia.

Octreotide / Lanreotide ikhoza kuwonjezera ndikuchepetsa kufunika kwa insulin.

Ethanoli (mowa) ikhoza kuwongolera ndikuchepetsa mphamvu ya insulin.

Kusagwirizana. Mankhwala ena, mwachitsanzo okhala ndi magulu a thiol kapena sulfite, akaphatikizidwa ku mankhwala a Levemir ® FlexPen ® angayambitse kuwonongeka kwa insulin. Levemir ® FlexPen ® sayenera kuwonjezeredwa pazothetsera kulowetsedwa. Mankhwala sayenera kusakanikirana ndi mankhwala ena.

Mlingo ndi makonzedwe

Mankhwala Levemir ® FlexPen ® angagwiritsidwe ntchito onse ngati monotherapy monga basal insulin, komanso kuphatikiza ndi insulin. Itha kugwiritsidwanso ntchito limodzi ndi mankhwala amkamwa a hypoglycemic komanso / kapena GLP-1 receptor agonists.

Kuphatikiza ndi mankhwala amkamwa a hypoglycemic kapena kuwonjezera pa agonists a GLP-1 receptors mwa odwala akuluakulu, tikulimbikitsidwa kugwiritsa ntchito Levemir ® FlexPen ® kamodzi patsiku, kuyambira ndi mlingo wa 0.1-0.2 U / kg kapena 10 UNITS.

Levemir ® FlexPen ® ikhoza kutumikiridwa nthawi iliyonse masana, koma tsiku ndi tsiku. Mlingo wa Levemir ® FlexPen ® uyenera kusankhidwa payekha pazinthu zonse, kutengera zosowa za wodwala.

Mukamawonjezera agonist a GLP-1 receptors ku Levemir ®, tikulimbikitsidwa kuti muchepetse mlingo wa Levemir ® ndi 20% kuti muchepetse chiopsezo cha hypoglycemia. Pambuyo pake, mlingo uyenera kusankhidwa payekha.

Pakusintha kwa mlingo wa munthu m'magulu akuluakulu a matenda a shuga 2, malangizidwe otsatirawa amalimbikitsidwa (onani Gome 1).

Madzi a m'magazi a plasma amayesedwa popanda chakudya cham'mawaKusintha kwa mankhwala Levemir ® FlexPen ®, ED
> 10 mmol / L (180 mg / dL)+8
9.1-10 mmol / L (163-180 mg / dl)+6
8.1-9 mmol / L (145-162 mg / dl)+4
7.1-8 mmol / L (127-144 mg / dl)+2
6.1-7 mmol / L (109-126 mg / dl)+2
4.1-6 mmol / L (73-108 mg / dl)Palibe kusintha (mtengo wake)
3.1-4 mmol / L (56-72 mg / dl)-2
® FlexPen ® imagwiritsidwa ntchito ngati gawo la regimen yofunikira, iyenera kuyikidwa 1 kapena 2 pa tsiku, kutengera zosowa za wodwalayo. Mlingo wa Levemir ® FlexPen ® uyenera kusankhidwa payekha.

Odwala omwe amafunikira kugwiritsa ntchito mankhwalawa kawiri pa tsiku kuti azitha kuyendetsa bwino glycemic, amatha kulowa mgonero ngakhale nthawi yamadzulo kapena asanagone. Kusintha kwa Mlingo kumakhala kofunikira pakulimbitsa thupi la wodwalayo, kusintha zakudya zake wamba kapena zodwala.

Chotsani kuchokera kukonzekera kwina kwa insulin. Kusintha kuchokera pakukonzekera kwapakati kapena nthawi yayitali kukonzekera inshuwaransi ku Levemir ® FlexPen ® kungafune kusintha kwa mlingo ndi nthawi (onani "Maupangiri Apadera").

Monga momwe amakonzera insulin ina, kuwunika mosamala kuchuluka kwa shuga wamagazi pakasamu komanso m'milungu yoyamba yatsopano ndikulimbikitsidwa.

Malangizo a concomitant hypoglycemic therapy (mlingo ndi nthawi ya makonzedwe osakhalitsa a insulin kukonzekera kapena mlingo wa pakamwa hypoglycemic mankhwala angafunike.

Njira yogwiritsira ntchito. Levemir ® FlexPen ® idapangidwa kuti ikwaniritse zokhazokha. Levemir ® FlexPen ® silingathe kutumizidwa iv. izi zimatha kuyambitsa kwambiri hypoglycemia. M'pofunikanso kupewa jakisoni wa IM. Levemir ® FlexPen ® sangagwiritsidwe ntchito pamapampu a insulini.

Levemir ® FlexPen ® imalowetsedwa pakatikati pa khoma lachiberekero lakumbuyo, ntchafu, matako, phewa, mapewa kapena dera la gluteal. Masamba a jakisoni amayenera kusinthidwa pafupipafupi m'dera lomwelo kuti muchepetse chiopsezo cha lipodystrophy. Monga kukonzekera kwina kwa insulin, kutalika kwa zochita zimatengera mlingo, malo oyendetsera, kutsika kwa magazi, kutentha ndi mulingo wakuchita zolimbitsa thupi.

Magulu apadera a odwala

Monga momwe amakonzera insulin ena, odwala ndi odwala omwe ali ndi vuto la impso kapena hepatic, kuyang'aniridwa kwa shuga wamagazi kuyenera kuyang'aniridwa mosamala kwambiri komanso mlingo wa kununkhira payokha.

Ana ndi achinyamata. Mankhwala Levemir ® angagwiritsidwe ntchito pochiza achinyamata ndi ana osaposa chaka chimodzi (onani "Pharmacodynamics", "Pharmacokinetics"). Mukamasintha kuchokera ku basal insulin kupita ku Levemir ®, ndikofunikira munthawi zonse kuganizira kufunika kochepetsa mlingo wa basal ndi bolus insulin kuti muchepetse chiopsezo cha hypoglycemia (onani. "Malangizo apadera").

Chitetezo ndi kugwira ntchito kwa Levemir ® mwa ana osakwana chaka chimodzi sizinaphunzire. Palibe zambiri zomwe zilipo.

Malangizo kwa wodwala

Osagwiritsa ntchito Levemir ® FlexPen ®

- pa nkhani ya ziwengo (hypersensitivity) kuti insulin, detemir kapena chilichonse cha mankhwala.

- ngati wodwala ayamba hypoglycemia (shuga wochepa wamagazi),

- m'mapampu a insulin,

- cholembera cha syringe ya FlexPen ® chikaponyedwa, chimawonongeka kapena kuphwanyidwa,

- ngati malo osungiramo mankhwalawo adaphwanyidwa kapena ndiuma;

- ngati insulini yasiya kukhala yowonekera komanso yopanda utoto.

Musanagwiritse ntchito Levemir ® FlexPen ®, ndikofunikira

- yang'aninso chizindikiro choti wodwalayo akugwiritsa ntchito bwino insulin,

- Gwiritsani ntchito singano yatsopano jakisoni iliyonse popewa matenda.

- zindikirani kuti Levemir ® FlexPen ® ndi singano zimapangidwa kuti azigwiritsa ntchito payekha.

Levemir ® FlexPen ® idapangidwa kuti ikwaniritse zokhazokha. Osachilowetsani mu / mkati kapena mu / m. Nthawi iliyonse, sinthani malo opangira jekeseni mkati mwa gawo la anatomical. Izi zimachepetsa chiwopsezo cha zisindikizo ndi zilonda pamalo a jekeseni. Ndikofunika kubaya mankhwalawo kutsogolo kwa ntchafu, matako, khoma lam'mimba lakutsogolo, ndi phewa. Nthawi zonse muyeze magazi anu.

Muyenera kuwerenga malangizo awa musanagwiritse ntchito Levemir ® FlexPen ®. Wodwala ngati sakutsatira malangizowo, amatha kupereka insulin yokwanira kapena yayikulu kwambiri, yomwe ingayambitse kuchuluka kwambiri kwa shuga m'magazi.

Flexpen ® ndi cholembera chodzaza ndi insulini cholembera chotsatsira. Mlingo wa insulin womwe umayendetsedwa, kuyambira 1 mpaka 60 mayunitsi, umatha kusiyanasiyana mu 1 unit. FlexPen ® idapangidwa kuti igwiritsidwe ntchito ndi singano za NovoFine ® ndi NovoTvist ® mpaka 8 mm. Monga kusamala, nthawi zonse ndikofunikira kuti mupereke inshuwaransi nanu kuti mupereke insulin kuti muwoneke kapena kuwononga cholembera cha Levemir ® FlexPen ® syringe.

Kusunga ndi chisamaliro

FlexPen ® Syringe pen imafunika kusamalira bwino. Pakakhala kugwa kapena kupanikizika kwamakina mwamphamvu, cholembera chimatha kuwonongeka ndipo insulin imatha kudontha.Izi zimatha kuyambitsa Mlingo wosayenera, womwe ungayambitse kuchuluka kwambiri kwa glucose kapena kutsika kwambiri.

Pamwamba pa cholembera cha FlexPen ® syringe imatha kutsukidwa ndi swab ya thonje ikamizidwa mu mowa. Osamiza cholembera chindende, osachisambitsa kapena kumuthira mafuta, monga izi zitha kuwononga makina. Kudzazitsa cholembera cha syringe ya FlexPen ® sikuloledwa.

Kukonzekera Levemir ® FlexPen ®

Musanayambe ntchito, ndikofunikira kuyang'ana chizindikiro kuti zitsimikizike kuti Levemir ® FlexPen ® ilipo ndi mtundu wa insulin womwe umafunikira. Izi ndizofunikira kwambiri ngati wodwala agwiritsa ntchito ma insulin osiyanasiyana. Akalakwitsa inshuwaransi yamtundu wina, kuchuluka kwa shuga m'magazi kumatha kukhala kokwanira kwambiri kapena kotsika.

A. Chotsani kapu ku cholembera.

B. Chotsani chomata kuchotsekera ku singano yotaya. Pindani singano mwamphamvu pa cholembera.

C. Chotsani kapu yayikulu yakunja kuchokera singano, koma osataya.

D. Chotsani ndikutaya kapu yamkati ya singano. Popewa kubayidwa mwangozi, musabwezeretsenso singano yamkati pabowo.

Chidziwitso chofunikira. Gwiritsani ntchito singano yatsopano jekeseni iliyonse. Izi zimachepetsa chiopsezo cha kuipitsidwa, kachilomboka, kutuluka kwa insulin, kutuluka kwa singano ndikukhazikitsa njira yolakwika ya mankhwala.

Gwirani singano mosamala kuti musapinde kapena kuwononga musanagwiritse ntchito.

Chingwe cha Insulin

Ngakhale mutagwiritsidwa ntchito moyenera ndi cholembera, mpweya wochepa umatha kudziunjikira mu cartridge musanadye jekeseni iliyonse. Poletsa kulowa kwa kuwira kwa mpweya ndikuwonetsa kuyamwa kwa mtundu woyenera wa mankhwalawa:

E. Imbani 2 magawo a mankhwala ndikusintha chosankha.

F. Pogwira cholembera cha FlexPen ® ndi singano mmwamba, ikani kanyumba kakang'ono kangapo ndi chala chanu kuti thovu la mpweya lithe pamwamba.

G. Kugwira cholembera ndi singano kumtunda, kanikizani batani loyambira njira yonse. Wosankha wa mankhwalawa amabwerera ku zero. Dontho la insulin liyenera kuonekera kumapeto kwa singano. Ngati izi sizingachitike, sinthani singano ndikubwereza njirayi, koma osapitirira 6.

Ngati insulini siyikuchokera singano, izi zikuwonetsa kuti cholembera sichili chosalongosoka ndipo sayenera kugwiritsanso ntchito. Gwiritsani ntchito cholembera chatsopano.

Chidziwitso chofunikira. Pamaso pa jekeseni iliyonse, onetsetsani kuti dontho la insulin limatuluka kumapeto kwa singano. Izi zimapangitsa kuti insulin iperekedwe. Ngati dontho la insulini silikuwoneka, mlingo wake sudzaperekedwa, ngakhale wosankha dokotala asuntha. Izi zitha kuwonetsa kuti singanoyo yaboweka kapena yowonongeka.

Yang'anani kuperekera kwa insulin musanayambe kubayidwa aliyense. Wodwalayo akapanda kufufuza insulin, sangathe kupereka insulin yokwanira kapena ayi, zomwe zingayambitse kuchuluka kwa shuga m'magazi.

Onetsetsani kuti chosankha cha mankhwalawo chikhala "0".

H. Sungani ziwerengero zomwe zimafunikira jakisoni. Mlingo umatha kusinthidwa ndikusinthanitsa ndi mtundu wosankhidwa mwanjira iliyonse mpaka mlingo woyenera wakhazikitsidwa kutsogolo kwa chizindikiro. Mukazungulira chosankha cha mlingo, chisamaliro chimayenera kutengedwa kuti asakanize mwangozi batani loyambira kuti muchepetse kutulutsa kwa insulin. Sizotheka kukhazikitsa mlingo woposa kuchuluka kwa zigawo zomwe zatsalira mu cartridge.

Chidziwitso chofunikira. Pamaso jakisoni, nthawi zonse muziwunika magawo a insulini omwe wodwalayo walosera ndi chosankha cha mankhwala ndi chizindikiro.

Osawerengetsa zokhoma za cholembera. Wodwala akangokhala ndikuyendetsa mlingo woyenera, kuchuluka kwa shuga m'magazi kumatha kukwera kwambiri kapena kutsika. Mlingo wa insulini ukuwonetsa kuchuluka kwa insulini yotsalira mu cholembera, motero sangagwiritsidwe ntchito kuyeza kuchuluka kwa insulin.

Ikani singano pansi pa khungu. Gwiritsani ntchito njira ya jakisoni yomwe dokotala wanu kapena namwino anu adayambitsa.

Ine. Kuti mupeze jakisoni, dinani batani loyambira mpaka "0" akuwonekera kutsogolo kwa chizindikiro. Chenjezo liyenera kuchitidwa, popereka mankhwala, batani loyambira lokha liyenera kukanikizidwa.

Chidziwitso chofunikira. Mukatembenuza wokonza mlingo, insulini siyidzayambitsidwa.

J. Mukachotsa singano pansi pa khungu, gwiritsani batani loyambira ndikukhumudwa kwathunthu.

Pambuyo pa jekeseni, siyani singano pansi pa khungu kwa masekondi 6 osachepera - izi zitsimikizira kuyambitsidwa kwa insulin yonse.

Chidziwitso chofunikira. Chotsani singano pansi pa khungu ndikumasulira batani loyambira. Onetsetsani kuti wosankha wa mankhwalawa amabwerera zero pambuyo pobayira. Ngati chosankha cha dokotala chayimira asanawonetse "0", insulin yonse siyinaperekedwe, zomwe zingayambitse kuchuluka kwa shuga m'magazi.

K. Wongoletsani singano mumkono wakunja wa singano musakhudze kapu. Pamene singano ilowa, valani chovalacho kwathunthu ndikuvula singano.

Tayani singano, onani njira zotetezera, ndipo ikani chophimbacho pa cholembera.

Chidziwitso chofunikira. Chotsani singano pambuyo pa jekeseni iliyonse ndikusunga Levemir ® FlexPen ® ndi singano yolumikizidwa. Izi zimachepetsa chiopsezo cha kuipitsidwa, kachilomboka, kutuluka kwa insulin, kutuluka kwa singano ndikukhazikitsa njira yolakwika ya mankhwala.

Chidziwitso chofunikira. Osamalira odwala ayenera kugwiritsa ntchito singano zogwiritsidwa ntchito mosamala kwambiri kuti achepetse ngozi ya jakisoni mwangozi komanso matenda opatsirana.

Tayani ntchito FlexPen ® ndi singano yokhazikika.

Musagawireko cholembera ndi singano yanu kwa ena. Izi zimatha kudzetsa matenda opatsirana ndikuvulaza thanzi.

Sungani cholembera ndi singano kuti aliyense asazifikire, makamaka ana.

Wopanga

Mwini wa satifiketi yolembetsa: Novo Nordisk A / S, Novo Alle DK-2880 Baggswerd, Denmark.

Yopangidwa ndi: Novo Nordisk LLC 248009, Russia, Kaluga Region, Kaluga, 2nd Automotive Ave, 1.

Zodandaula za makasitomala ziyenera kutumizidwa kwa: Novo Nordisk LLC. 121614, Moscow, st. Krylatskaya, 15, wa. 41.

Tele. ((495) 956-11-32, fakisi: (495) 956-50-13.

Levemir ® FlexPen ®, NovoFine ® ndi NovoTvist ® ndi zilembo zolembetsedwa ndi Novo Nordisk A / C, Denmark.

Kusiya Ndemanga Yanu