Mukamamwa pakamwa, alpha-lipoic acid imatengedwa mwachangu komanso imafalikira kwathunthu kuchokera m'matumbo, imapangidwa makamaka mu chiwindi ndi makutidwe a mitondo yam'mbali ndi kuphatikizika. Mankhwala amathandizidwa kudzera mu impso (93-97%), makamaka mu mawonekedwe a metabolites. Kutha kwa theka-moyo ndi mphindi 10-20.

Pharmacodynamics ndi pharmacokinetics

Zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimakhala coenzyme mu oxidative decarboxylation alpha keto acid. Zimakhudza mphamvu cell kagayidwe.

Mankhwalawa amachita ngati antitoxic ndi antioxidant amatanthauza, ndipo amathanso kubwezeretsa zina antioxidants. Nthawi zambiri imagwiritsidwa ntchito pa matenda ashuga, Pankhaniyi, mankhwalawa amachepetsa kukana insulin ndipo imalepheretsa chitukuko zotumphukira neuropathy. Dialipon imathandizira kutsika shuga mu magazi ndipo zimathandizira kuti zikhale zochuluka glycogen mu chiwindi.

Gawo lomwe likukhudzidwa ndi mankhwalawo limakhudzidwa mafuta ndi chakudya kagayidwe kachakudya, komanso kusintha matenda a chiwindi.

Hafu ya moyo wa mankhwalawa ndi mphindi 30. Pambuyo kugwiritsa ntchito yankho limodzi mu 3 mpaka maola 6.6 alpha lipoic acid ndi iye zotumphukira pafupifupi owerengedwa mwanjira yachilengedwe.

Zotsatira zoyipa

Ndi kukhazikitsa mwachangu yankho, kumva kupweteka m'mutu, kusanza, nseru, kupuma. Zotsatira zoyipa zomwe zimachitika zokha.

Odwala ena atero thupi lawo siligwirizana pa jekeseni: urticaria, chikanga. Amatha kufalikira thupi lonse. Zodziwikanso kukokana, petechial zidzolo, diplopiakuphwanya ntchito kuchuluka kwa mapulateleti. Ndi chidwi chochulukirapo, kupweteka kwambiri ndikotheka.

Nthawi zina, zimachitika anaphylactic mantha. Ndikotheka hypoglycemia.

Malangizo ogwiritsira ntchito Dialipon (Njira ndi Mlingo)

Kwa iwo omwe adayankhidwa Dialipon yankho, malangizo ogwiritsira ntchito akunena kuti mankhwalawo amagwiritsidwa ntchito kudzera m'mitsempha pa mlingo wa 10-20 ml patsiku. Mankhwala amayenera kuperekedwa pang'onopang'ono - osaposa 50 mg pa miniti. Analimbikitsa kulowetsedwa kugwiritsa ntchito mchere. Kuti muchite izi, 10-20 ml ya mankhwalawa imaphatikizidwa ndi yankho la 0.9% sodium chloride (200-250 ml). Kulowetsa khalani mphindi 20-30. Njira yothetsera vutoli iyenera kusungidwa m'malo amdima.

Kulowetsa chitani kwa masabata 2-4. Kenako tikulimbikitsidwa kusinthira kwa makapisozi a kapisolo. Mlingo wapamwamba wa Dialipon ndi 600 mg, ochepera ndi 300 mg. Imwani mankhwalawa kwa miyezi 1-3. Ndikofunika kuchititsa maphunziro a 2 kawiri pachaka, izi zimathandiza kuphatikiza zotsatira.

Mlingo

1 kapisozi muli

yogwirachinthu - alpha lipoic acid 0,3 g,

zokopa: lactose monohydrate, microcrystalline cellulose 101, hypromxose (hydroxypropyl methyl cellulose) E 15, anhydrous colloidal silicon dioxide (aerosil), magnesium stearate

Kuphatikizika kwa kapisozi ya gelatin: chikasu chachitsulo (E 172), titanium dioxide E 171, gelatin.

Makatoni olimba a gelatin No. 0, wokhala ndi thupi komanso minyanga ya chivindikiro. Zolemba za Capsule - Kusakanikirana Kwachikasu

Kuchita

Mankhwala amatha kuchepetsa zovuta zamagawo azitsulo. Ndi mashuga alpha lipoic acidamapanga bwino sungunuka mankhwala osakanikirana.

Simungathe kuphatikiza mankhwalawo shuga njira, Ringer ndi fructose. Kuphatikiza apo, singaphatikizidwe ndi othandizira omwe amaphatikiza mankhwala omwe amakhudzidwa ndi Magulu a SH kapena sakani milatho.

Ngati ntchito insulin kapena m`kamwa hypoglycemic mankhwala amatha kulimbikitsidwa hypoglycemic chochita, chifukwa chake, kuwunikira nthawi zonse pamlingo kumafunika glycemia, makamaka kumayambiriro kwa zamankhwala. Nthawi zina, kuchepetsa kumwa kumafunika. insulin ndi hypoglycemic ndalama za pamlomo ntchito.

Ndemanga za Dialipone

Malingaliro okhudzana ndi mankhwalawa amakhala abwino. Odwala amadziwa kuti imathandizira kuti shuga azitha magazi ndipo imathandiza poyizoni. Ponena za zoperewera za mankhwalawa, kuwunika kwa Dialipone kumawerengera zovuta zambiri komanso mtengo wokwera.

Dialipon wa mankhwala: malangizo ogwiritsira ntchito

Kugwiritsa ntchito Dialipon tikulimbikitsidwa kusintha kagayidwe kachakudya ndi kupangitsa kuti poizoniyo akhale woopsa poyizoni wazitsulo komanso chiwindi.

Onse mkamwa ndi mtsempha wamkati tikulimbikitsidwa.

Dzinalo Losayenerana

Alpha lipoic acid ndi dzina lazinthu zomwe zimagwira.

Kugwiritsa ntchito Dialipon tikulimbikitsidwa kusintha kagayidwe kachakudya ndi kuchepetsa zotsatira zakupha poyizoni.

A16AX01 - code for anatomical-achire mankhwala-mankhwala.

Kutulutsa mafomu ndi kapangidwe kake

Mankhwala amapezeka mu mawonekedwe a madzi a jekeseni wamkati ndi mawonekedwe a kapisozi. Ndi dokotala yekha yemwe amawona kuthekera kogwiritsa ntchito yankho kapena makapisozi pakamwa.

Dialipon Turbo amapangidwa m'mabotolo agalasi 50 ml. The zikuchokera mankhwala kulowetsedwa zikuphatikizapo 0,6 ga yogwira pophika.

Njira yothetsera vutoli imapangidwa ndikumatengera makatoni 10 mabotolo 10 mu lirilonse la iwo.

Dialipon Turbo amapangidwa m'mabotolo agalasi 50 ml.

Kuphatikiza apo, mankhwalawa amapangidwa mu ma ampoules, omwe kuchuluka kwake ndi 20 ml (kuchuluka kwa gawo logwira ntchito ndi 30 mg / ml).

1 kapisozi muli 300 mg ya alpha lipoic acid.

Chogulikacho chimapezeka m'matumba a 10 makapisozi mumitundu iliyonse.

Zotsatira za pharmacological

Ndikofunikira kuganizira izi:

1. Gawo logwira limakhudza kagayidwe.
2. Mankhwala ali ndi antioxidant.
3. Alpha-lipoic acid amachepetsa kukana kwa insulini, kuletsa kukula kwa matenda ashuga a polyneuropathy (kusokonekera kwa mitsempha ya zotumphukira).
4. Chida chimasinthasintha magwiridwe antchito a chiwindi.

Contraindication

Mankhwala sangathe kugwiritsidwa ntchito mwazinthu zingapo:

• cholowa cha galactose chosaloledwa,
• Hypersensitivity pamagawo a mankhwala,
• kuchepa kwa lactase
• kulephera kwa mtima (pali chiopsezo chachikulu cha acidosis),
• zovuta zamagazi ozungulira muubongo,
• kutaya mtima chifukwa cha uchidakwa wambiri.

Momwe mungatengere

Ndikofunikira kuganizira zingapo monga izi:

1. Mankhwala kutumikiridwa m`nsinga pa mankhwala osachepera 20 ml patsiku.
2. Mankhwala ayenera kuikidwa pang'onopang'ono.
3. Kwa infusions, saline iyenera kugwiritsidwa ntchito.
4. Kutalika kwa kulowetsedwa ndi mphindi 20. Kosi ya milungu iwiri imafunika.
5. Makapisozi amatchulidwa atatsiriza mankhwala a dialipon mu mawonekedwe a madzi.
6. Mlingo wapamwamba wa tsiku ndi tsiku wa Dialipon wogwiritsidwa ntchito pakamwa ndi 600 mg.
7. Makapisozi amatengedwa mkati mwa miyezi 1-2.
8. Njira ya mankhwala ndi mankhwala tikulimbikitsidwa kutenga kawiri pachaka.

Njira yogwiritsira ntchito

Mankhwala Dialipon ntchito pakamwa pa 600 mg 1 nthawi patsiku.
Mankhwalawa amatengedwa popanda kutafuna, kutsukidwa ndimadzi pang'ono, m'mawa 30-45 musanadye.
Milandu yovuta kwambiri yokhudzana ndi matenda a shuga a polyneuropathy, chithandizo chiyenera kuyambitsidwa ndi kholo la alpha-lipoic acid (njira ya Dialipon ya jekeseni) kwa masabata 2-4. Kenako, m`kamwa makonzedwe a mankhwala muyezo wa 600 mg 1 nthawi patsiku ayenera kupitiriza.
Kutalika kwa chithandizo kumatengera mtundu ndi njira ya matendawa ndipo adatsimikiza ndi dokotala.

Mankhwala

Pharmacokinetics

Mukamamwa pakamwa, alpha-lipoic acid imatengedwa mwachangu komanso imafalikira kwathunthu kuchokera m'matumbo, imapangidwa makamaka mu chiwindi ndi makutidwe a mitondo yam'mbali ndi kuphatikizika. Mankhwala amathandizidwa kudzera mu impso (93-97%), makamaka mu mawonekedwe a metabolites. Kutha kwa theka-moyo ndi mphindi 10-20.

Mankhwala

Alpha lipoic acid imapangidwa m'thupi ndipo imagwira ngati coenzyme mu oxidative decarboxylation ya -keto acid, imachita mbali yofunika kwambiri pakupanga mphamvu kwa cell. Mu mawonekedwe amide (lipoamide) ndi cofactor yofunikira ya ma enzyme angapo ophatikizika omwe amachititsa ma decarboxylation a -keto acids of the Krebs mzunguko. Alfa-lipoic acid ali ndi chibadwa chogwira antitoxic ndi antioxidant, amathanso kubwezeretsa ma antioxidants ena, mwachitsanzo, matenda a shuga. Odwala omwe ali ndi matenda ashuga, alpha-lipoic acid amachepetsa kukana kwa insulin ndipo amalepheretsa chitukuko cha zotumphukira za m'mitsempha. Zimathandizira kuchepetsa shuga wamagazi ndi kuchuluka kwa glycogen m'chiwindi. Alpha lipoic acid imakhudzanso kagayidwe ka cholesterol, imatenga nawo mbali pakuwongolera kwa lipid ndi carbohydrate metabolism, imayendetsa ntchito ya chiwindi (chifukwa cha hepatoprotective, antioxidant, detoxification zotsatira).

Bongo

Milandu yokhudzana ndi kuledzera kwa alpha-lipoic acid sananenedwe, kuphatikiza apo, chifukwa cha kupezeka kwa mankhwalawa chifukwa cha zinthu, siziyenera kuyembekezeredwa. Ngati bongo, nseru, kusanza, kupweteka kwa mutu ndikotheka.
Mukamagwiritsa ntchito alpha-lipoic acid wokwanira kwambiri (10 mpaka 40 g) ndi mowa, kuledzera kwamphamvu kumawonedwa, komwe kumatha kupha. Zizindikiro zamankhwala zakumwa zoledzeretsa zimawonetsedwa ngati vuto la psychomotor kapena kukomoka kutsatiridwa ndi kukomoka kwina komanso kukula kwa lactic acidosis. Kuledzera kwa alpha-lipoic acid kumapangitsa hypoglycemia, kugwedezeka, kuchepa kwa magazi, hemolysis, kugawa intravascular coagulation, kuponderezana kwam'mafupa komanso kufooka kwa ziwalo.
Poizoni wakupha ndi alpha-lipoic acid, kugonekedwa kuchipatala mwachangu ndi njira zochizira zothetsera thupi (kupuma movutikira, kusanza, kupweteka kwa m'mimba, makala oyambitsa, ndi zina zambiri). Zochizira kukomoka kwakukulu, lactic acidosis ndi zovuta zina za kuledzera, munthu akuyenera kuwongoleredwa ndi njira zamakono zamankhwala osamalitsa komanso njira yodziwitsira yolimbikitsa kutulutsa kwa alpha-lipoic acid. Mankhwala ena ndiwowonekera.

Kutulutsa Fomu

Dialipon - makapisozi.
Makapisozi 10 pachimake. Pa matuza atatu kapena 6 omwe atsekedwa mu paketi.

1 kapisoziDialipon muli 0,300 g alpha lipoic acid
Omwe amathandizira: lactose monohydrate, microcrystalline cellulose, hypromellose (hydroxypropyl methylcellulose) E15, anhydrous colloidal silicon dioxide (aerosil), magnesium stearate.

Zizindikiro zogwiritsidwa ntchito

Makapisozi onse ndi yankho zimayikidwa ndi adotolo pamaziko a mayeso ndi kuzindikira. Ndi mtundu uti wa mankhwalawa omwe angasankhe zimatengera kuzindikira kwake pazokulira.

Kanema: "Peripheral polyneuropathy"

Malangizo apadera ogwiritsira ntchito Dialipon

• Panthawi ya makonzedwe, kuwonjezeka kwa chidwi cha mathero a mitsempha kumatha kuchitika., mawonekedwe a goosebumps. Simungathe kuyang'ana pa izi, chifukwa izi sizikugwira ntchito pazotsatira zoyipa.
• Mankhwala, muyenera kusiya kumwa mankhwala aliwonse osokoneza bongo, chifukwa amachepetsa mphamvu ya alpha-lipoic acid, potero amachepetsa mphamvu ya mankhwalawa.
• Musagwiritse ntchito nokha, makamaka pochiza ana osaposa zaka 18.
• Njira yokonzekerayo itakulungidwa mu thumba lakuda pulasitiki kuchokera pakuwala, momwe angagwiritsidwire ntchito kwa maola 6, ngakhale pali zochulukirapo.
• Palibe malangizo apadera oyendetsa magalimoto kapena kugwira ntchito zina zofunika pakuwonjezera chidwi, ngati zotsatira zoyipa zikuwonekera, ndikosayenera kuchita izi.
• Simuyenera kugwiritsa ntchito Dialipon ndikugwiritsa ntchito mwankhanza mankhwala a mkaka ndi zakudya zomwe zimakhala ndi calcium yambiri.

Migwirizano ndi magwiritsidwe akusungidwa

Ndikofunikira kusungidwa pamalo abwino kwambiri, osagwiritsidwa ntchito kuti azitsogolera dzuwa. Kutentha kosungirako 15-16 madigiri. Tsiku lotha ntchito zaka 3.

Ndikofunika kukumbukira kuti kugwiritsa ntchito mankhwala omwe amapanga mankhwala okhala ndi nthawi yomwe ntchito yawo yatha kapena kumaliza ntchito sikuletsedwa.

Mankhwala oterowo sangathe kungotengera matenda mwanjira iliyonse, komanso angayambitse zotsatira zosayembekezereka, poyizoni ndi zotsatira zina.

Dialipon ndi mankhwala okwera mtengo, omwe ndi vuto lake losatsutsika.

Ku Russia muyenera kupereka kuchokera 400 mpaka 600 rubles, zimatengera dera komanso mankhwala.

Ku Ukraine mtengo wapakati 240-270 hryvnia.

Koma ngakhale wodwalayo alibe mwayi wogula, mutha kugwiritsa ntchito analogue yofananira ndikuwoneka.

Ndemanga zamakasitomala

Ngakhale pali zotsutsana zambiri komanso zoyipa, zochuluka anthu omwe amathandizidwa ndi mankhwalawa adakhuta - pafupifupi 80%.

Zinadziwika kuti kusintha kwa thanzi kumadziwika kwambiri atangoyamba kumene mankhwala.

Akatswiri amamukondanso kuti azigwira ntchito kwambiri. ndi mitundu yambiri yamapulogalamu.

Komabe ambiri taona kuti sichingagwiritsidwe ntchito ndi ana komanso mtengo wake wokwera, sanathandize ena, ndipo adayenera kusintha njira yonse ya chithandizo. Koma ndikuyenera kuyang'anira chidwi chochuluka.

Ndemanga zonse zimatha kuwerengedwa kumapeto kwa nkhaniyo.

Mwachidule, titha kunena kuti mankhwalawa Dialipon ndiyabwino matenda ashuga, poyizoni, mavuto a chiwindi komanso matenda ena..

Koma iyenera kugwiritsidwa ntchito mosamala, pazotsatira za dokotala, yemwe, kuphatikiza pa mankhwala, adzasankha Mlingo wofunikira.

Zabwino sangathe kuthandizidwa ndi ana komanso amayi oyembekezera, anthu omwe amawaganizira ndi zigawo za mankhwalawo. Mtengo wake sunali wocheperako, koma wokwera mtengo, ndipo ngati palibe njira yoti mugule, kusinthanitsa ndi analog sikuletsedwa ndi madokotala.

Zokhudza mphamvu pakuwongolera njira

Sizikhudzanso kuyendetsa galimoto, motero, kuchotsedwa kwa mankhwala sikofunikira ngati wodwala azichita chidwi ndi chidwi.

Dialipon sichimayendetsa kuyendetsa.