Momwe mungagwiritsire ntchito Metformin Zentiva?

Metformin ndi njira yothandiza yolimbana ndi shuga wamagazi ambiri. Kuphatikiza pa kukonza mankhwalawa a shuga, mankhwalawa amagwiritsidwa ntchito mwakhama kuchepetsa thupi. Katunduyu ndi m'gulu la Biguanides. Pali maphunziro angapo omwe amatsimikizira kuti, kuwonjezera pa katundu wake wa hypoglycemic, metformin hydrochloride imathandiza kuchepetsa chiopsezo cha khansa ya kapamba.

Zotsatira za pharmacological

Chochita chachikulu cha Metformin ndi kuchepa kwa plasma glucose. Komabe, sizimalimbikitsa kupanga insulin, chifukwa cha ichi palibe chiopsezo cha hypoglycemia.

Achire zotsatira za mankhwalawa ndi chifukwa amatha kuyambitsa zotumphukira zolandilira, kukulitsa chidwi chawo ndi insulin. Kuphatikiza apo, metformin:

amalepheretsa kupanga kwa shuga kwa chiwindi,
amalepheretsa mayamwidwe a shuga m'matumbo,
imathandizira kugwiritsidwa ntchito kwa shuga mkati ndi glycogen synthesis,
amachulukitsa kuchuluka kwa shuga m'magulu amtundu wa cell,
imayendetsa mafuta kagayidwe, kuchepetsa zomwe triglycerides, otsika osalimba lipoproteins ndi okwanira mafuta m'thupi.

Chochita chachikulu cha Metformin ndi kuchepa kwa plasma glucose. Komabe, sizimalimbikitsa kupanga insulin, chifukwa cha ichi palibe chiopsezo cha hypoglycemia.

Zomwe zimayikidwa

Kuvomerezedwa kwa mankhwalawa kumasonyezedwa kwa mtundu wachiwiri wa matenda osokoneza bongo, makamaka zovuta kunenepa. Chifukwa chakutha kusintha njira za metabolic, mankhwalawa ndi chida chothandiza kuthana ndi kunenepa kwambiri.

Kugwiritsa ntchito Trental 100 kumathandizira kuyenderera kwa magazi ndikuyenda bwino m'mitsempha yamagazi.

Potupa pakubuka kwa mabakiteriya, mapiritsi a Gentamicin amagwiritsidwa ntchito. Werengani zambiri apa.

Mankhwala Victoza: malangizo ntchito.

Contraindication

Kumwa mankhwalawa ndi contraindised mu:

kuchuluka kwa magawo ake,
matenda ashuga ketoacidosis,
matenda a shuga
kulephera kwapakati kapena kwambiri,
kusowa kwamadzi ndi zinthu zina zomwe zingayambitse vuto la impso,
kulephera kupuma komanso zinthu zina zomwe zimayambitsa minyewa hypoxia,
lactic acidosis,
chiwindi ntchito, kuledzera,
uchidakwa komanso uchidakwa.
mimba
kuperewera kwa kalori (kudya zakudya zosakwana 1000 kcal / tsiku),
kuchita opareshoni kapena maphunziro momwe chinthu cha radiopaque chimagwiritsidwa ntchito.

Metformin akuwonetsedwa ngati mtundu wa 2 matenda a shuga, makamaka ovuta kunenepa.

Zisonyezo zakugwiritsa ntchito mankhwala

Mankhwala Metformin zentiva akhala akugwiritsidwa ntchito ngati mankhwala ochizira matenda a shuga a 2 osakanikirana ndi zakudya zomwe dokotala wamupatsa.

Mankhwalawa samangobweretsa kuchuluka kwa glucose pamlingo woyenera ndi chizindikiro cha thupi, komanso zimapangitsa kuti achepetse thupi ndikuwongolera m'malo oyenera, chomwe ndichofunikira kwa anthu omwe ali ndi vutoli.

Masiku ano, chifukwa cha kafukufuku wopitilira, zinthu zatsopano za chinthuchi zikupezeka, ndipo kugwiritsa ntchito kwake kukukulira, kulola kugwiritsa ntchito mankhwalawa osati pakulimbana ndi matenda.

Metformin zentiva angagwiritsidwe ntchito pochotsa ndi kuchiza matenda otsatirawa:

Imathandizira kuteteza ubongo ku ukalamba, womwe umalola kuti uzigwiritsira ntchito prophylactic zolinga motsutsana ndi matenda a Alzheimer's.
Mosangalatsa zimakhudza mitsempha yamagazi ndi mitsempha. Chifukwa chake, mothandizidwa ndi metformin, kukula kwa mitsempha ya mitsempha, kulephera kwa mtima, matenda oopsa, komanso kupimitsa mtima kwamitsempha.
Amachepetsa mwayi wokhala ndi khansa.
Amathandizira kusintha kwa potency mwa abambo, omwe anali ndi vuto chifukwa cha matenda osiyanasiyana a senile.
Zimalepheretsa kukula kwa mafupa a anthu odwala matenda ashuga. Makamaka, nthawi zambiri, azimayi amakhala ndi vuto la mafupa osaneneka atasiya kusamba, popeza pali kuchepa kwakukulu kwamahomoni - estrogen.
Zokhudza bwino chithokomiro cha chithokomiro.
Ili ndi ntchito yoteteza mokhudzana ndi dongosolo la kupuma.

Ngakhale kuti mankhwalawa ali ndi zabwino zambiri, sizingatheke kunena kuti ndi athanzi ndipo amatha kuchiritsa matenda ambiri.

Monga mankhwala ena, metformin imatha kugwiritsidwa ntchito monga momwe dokotala amafotokozera, momwe mungathere ndi zovuta zake zonse.

Pharmacological zimatha piritsi

Mankhwalawa ndi a gulu la Biguanides, lomwe limagwiritsidwa ntchito pakamwa.

Mankhwalawa a hypoglycemic amathandizira kutsika kwam'magazi a shuga.

Chimodzi mwamaubwino amakulu a mankhwalawa ndikuti, mosiyana ndi mankhwala omwe amachokera ku sulfonylureas, sayambitsa hypoglycemia. Katunduyu amafotokozedwa ndikuti Metformin simalimbikitsa kutulutsa insulin chifukwa cha maselo a pancreatic beta.

Mukamamwa molondola, mankhwalawa amathandizira kuzindikira kwa zotumphukira za minyewa yolumikizira insulin, zomwe zimapangitsa kuti shuga agwiritsidwe ntchito kwambiri ndi maselo odalira insulin. Zimathandizira kuchepetsa kupanga kwa glucose ndi ma cell a chiwindi poletsa njira za gluconeogenesis ndi glycogenolysis. Mwa zina zabwino zimatha kuphatikizidwanso chifukwa chakuchepetsa mayamwidwe a shuga m'matumbo.

Zotsatira zabwino za metformin pa lipid metabolism zawonedwanso:

Kuchepetsa kolesterol kwathunthu,
zimathandizira kukonza magazi,
yachepetsa LDL ndi triglycerides.

Chofunikanso ndichakuti kusamalidwa kwa chakudya choyenera, limodzi ndi kugwiritsa ntchito metformin, kumathandizira kuchepa pang'onopang'ono m'thupi la wodwalayo.

Malangizo ogwiritsira ntchito mankhwalawa

Mankhwala Metformin Zentiva amapangidwa mu mawonekedwe a piritsi osiyanasiyana.

Wopanga mankhwalawa amapezeka ku Republic of Slovakia, pomwe Czech Republic imakhala ngati mwiniwake walembetsa.

Mankhwala atha kugulidwa pafupifupi ku malo aliwonse a mankhwalawa muyezo zotsatirazi:

500 mg yogwira piritsi limodzi,
850 mg yogwira ntchito
1000 mg ya metformin.

Kutengera mlingo wake, malamulo omwera mankhwalawa amatha kusiyanasiyana. Dziwani kuti ndi madokotala okhawo omwe angalimbikitse kugwiritsa ntchito mankhwalawa, kuphatikizapo m'malo mwa mankhwala omwe adamwa kale.

Njira yochizira imayikidwa mu Mlingo, womwe umatsimikiziridwa ndi zotsatira za kusanthula ndi maphunziro a thupi ndi machitidwe a wodwala. Chizindikiro chachikulu chomwe muyenera kulabadira mukamazindikira mlingo ndi kuchuluka kwa shuga m'magazi am'magazi komanso kuchuluka kwa odwala.

Mlingo wocheperapo womwe mankhwalawa amayamba ndi 500 mg ya mankhwalawa ndikuwonjezereka kwina. Komanso, muyezo umodzi womwewo sungathe kupitirira chiwerengero chomwe chatchulidwa pamwambapa. Kuti mulekerererane bwino mankhwalawo, komanso ngati pali Mlingo wokhazikika, kuchuluka kwake kungagawike pawiri kapena katatu masana. Chifukwa chake, zitha kuteteza kukula kwa zoyipa.

Mulingo woyenera wa mankhwalawa sayenera kupitirira 3000 mg yogwira ntchito.

Mankhwalawa amatengedwa pakamwa, pambuyo pake, patatha maola awiri kapena atatu, ntchito yake yayikulu imayamba kuonekera. Pafupifupi maola asanu ndi limodzi atatha kumwa mankhwalawa, plasma ndende ya metformin imachepa, popeza kuyamwa kwa chinthucho kumatha.

Nthawi zina, ndizovomerezeka kumwa mankhwalawa chifukwa cha prophylactic, ndipo mlingo uyenera kuchepetsedwa kawiri kapena katatu.

Kuchuluka kwa kumwa mankhwalawa kumatheka patatha milungu iwiri ya chithandizo.

Ngati, pazochitika zina, mankhwala adasowa, palibe chifukwa chowalipirira pochulukitsa mlingo wotsatira.

Mukamamwa mankhwalawa, ndikofunikira kuganizira njira yachilengedwe ya kagayidwe kachakudya ndi thanzi labwino, popeza pamakhala chiopsezo cha lactic acidosis.

Njira zopewera kugwiritsa ntchito mankhwalawa

Kugwiritsa ntchito molakwika kwa Metformin kumatha kuyambitsa zovuta zambiri, zovuta zamavuto a thupi la munthu atseguka. Ichi ndichifukwa chake mankhwalawa amayenera kuperekedwa ndi adokotala, poganizira zonse zomwe wodwalayo ali, kukula kwa chitukuko cha matenda ndi matenda ena okhudzana ndi matendawa.

Zowonetsa zazikulu za mankhwalawa zimaphatikizapo izi:

Kukula kwa mavuto ndi ziwalo zam'mimba, matenda am'mimba, omwe amatha kukhala limodzi ndi kupangidwa kwa mpweya, kupweteka m'mimba kapena m'mimba.
Zotsatira zosasangalatsa zachitsulo mkamwa zitha kuwoneka pambuyo povulala.
Kusanza ndi kusanza.
Kuperewera kwamagulu ena a mavitamini, makamaka B12. Ndi chifukwa chake, tikulimbikitsidwa kuti ena owonjezera a mankhwala osokoneza bongo omwe amatha kusintha mtundu wa zinthu zonse zofunika mthupi.
Kukula kwa thupi lawo siligwirizana ndi zigawo za chinthu cholemba.
Kutsika kwa shuga m'magazi m'munsi mwofunikira.
Mawonekedwe a lactic acidosis.
Megaloblastic anemia.

Ndipo ngakhale Metformin ikuphatikizidwa ndi gulu la mankhwala otetezeka, muyenera kuwerenga mosamala mawunikidwe onse oyipa. Mankhwala oterowo amatha kukhala owopsa ngati simutsatira malamulo oyenera kutsata.

Chimodzi mwazinthu zoyipa zomwe zimadza chifukwa chogwiritsa ntchito mankhwalawa ndi lactic acidosis mu shuga. Vutoli limayendera limodzi ndi zizindikiro monga kugona kwambiri, kuwonda minofu, kuchepa thupi komanso kuthamanga magazi, komanso kupuma movutikira.

Ndi kukula kwa matenda oterewa, wodwala amafunikira kuchipatala mwachangu. Lactic acidosis ndi imodzi mwazotsatira zoyipa zomwe zimachitika chifukwa cha mankhwala osokoneza bongo ambiri.

Metformin Zentiva ndi oletsedwa kugwiritsa ntchito pamaso pa chinthu chimodzi kapena zingapo:

metabolic acidosis mu mitundu kapena pachimake,
matenda a shuga kapena kholo,
Ndi mavuto akulu ku impso,
chifukwa chamadzi am'madzi,
matenda akuluakulu opatsirana akaonekera kapena pambuyo pawo.
kulephera kwamtima kapena kulowerera m'mitsempha,
mavuto ndi yachibadwa ntchito kwa kupuma thirakiti,
uchidakwa wosatha.

Amaletsanso kumwa mankhwalawa tsiku lisanafike komanso atatha kuchitidwa opaleshoni (ayenera kutha masiku osachepera masiku awiri ntchito isanachitike komanso masiku awiri itatha).

Ma Analogs a Metformin Zentiva

Maumboni a odwala amawonetsa zabwino zomwe chithandizo cha metformin chimabweretsa. Mtengo wake wapadera m'gawo la Russian Federation ukhoza kuchoka pa 100 mpaka 150 ma ruble, kutengera malo omwe amapezeka.

Ngati ndi kotheka, dokotala yemwe amapezekapo akhoza kusintha mankhwala ena ndi omwewo kapena mawonekedwe omwewo. Mpaka pano, msika wama pharmacological umapereka fanizo zotsatirazi za mankhwala a Metformin, omwe, malinga ndi ndemanga, amakhalanso ndi zotsatirapo zabwino:

Glucophage - mapiritsi ochepetsera shuga omwe amapezeka mosiyanasiyana. Chofunikira chachikulu ndi metformin hydrochloride. Zimathandizira kukula kwamwazi wamagazi popanda kuchititsa hypoglycemia. Gawo lamitengo yamapiritsi oterowo, monga lamulo, sapitilira ma ruble 200.
Glycon ndi mankhwala, omwe amapangika pomwe pali zinthu ziwiri zogwira ntchito nthawi imodzi - metformin ndi glibenclamide. Ichi ndi mankhwala osakanikirana omwe amaphatikiza mphamvu za Biguanides ndi sulfonylureas. Nthawi zambiri amagwiritsidwa ntchito pochiza matenda a shuga II. Mtengo wapakati wa mankhwalawo ndi ma ruble 210-240.
Diasphor ndi mankhwala ochokera pagulu la Biguanide, omwe ndi chithunzi chonse cha mapiritsi a Metformin. Mtengo wake wapakati pamasitolo azitawuni amatha kukhala 250 mpaka 350 rubles.
Metadiene - mapiritsi ochokera ku kalasi ya dimethylbiguanides, omwe amapezeka osiyanasiyana. Kutengera kuchuluka kwa zinthu zomwe zimagwira, mtengo wa mankhwalawo umakhazikitsidwa. Monga lamulo, mtengo wa Sofamed m'magawo osiyanasiyana amzindawu sapitilira ma ruble 130.
Nova Met.
Glibenclamide.

Mpaka pano, kuchuluka kwa ma analogi kapena kutengera mawu ndi zambiri. Onsewa, monga lamulo, ali ndi zofanana kapena zofanana, koma amasiyana makampani opanga, mtengo, dzina.

Kuphatikiza apo, akatswiri azachipatala amalimbikitsa kugwiritsa ntchito zida zamankhwala zomwe zimakhala, kuphatikiza pa gawo lalikulu lomwe limagwira, ochepera othandizira.

Zambiri pazamankhwala Metformin zikuwonetsedwa mu kanema munkhaniyi.

Mankhwala

Metformin ndi biguanide yokhala ndi antihyperglycemic effect. Amachepetsa shuga m'magazi onse pamimba yopanda kanthu ndikatha kudya. Samalimbikitsa insulin katemera ndipo samayambitsa hypoglycemic effect yolumikizidwa ndi njirayi.

Metformin imagwira ntchito m'njira zitatu:

kumabweretsa kuchepa kwa kupanga kwa shuga m'chiwindi chifukwa cha kuletsa kwa gluconeogenesis ndi glycogenolysis,
bwino minofu insulin kudziwa, chifukwa bwino zotumphukira kuyamwa ndi shuga ntchito
Iachedwetsa mayamwidwe am'matumbo m'matumbo.

Metformin imathandizira kapangidwe ka glycogen mu intracellular mwa kuchita glycogen synthetases. Kuchulukitsa kuchuluka kwa mayendedwe a mitundu yonse yodziwika ya ma membrane glucose transport (GLUT).

Mosasamala kanthu za momwe zimakhudzira kuchuluka kwa shuga m'magazi, metformin imathandizira kagayidwe ka lipid. Metformin imatsitsa cholesterol yonse, otsika osalimba lipoprotein ndi triglycerides.

Panthawi ya mayesero azachipatala pogwiritsa ntchito metformin, kulemera kwamthupi la wodwalayo kunakhazikika kapena kumachepetsa.

Zogulitsa. Mutatenga metformin, nthawi yoti mufikire pazambiri (T max) ili pafupifupi maola 2,5. The bioavailability wa mapiritsi a 500 mg kapena 800 mg ndi pafupifupi 50-60%. Pambuyo pakukonzekera pakamwa, chidutswa chomwe sichikumwa ndipo chimalimbidwa ndi ndowe ndi 20-30%.

Pambuyo pakukonzekera pakamwa, kuyamwa kwa metformin kumakhala kokhazikika komanso kosakwanira.

Ma pharmacokinetics a mayamwidwe a metformin amawerengedwa kuti ndi osagwirizana. Mukamagwiritsidwa ntchito pazovomerezeka za metformin ndi regimens, makulidwe amodzi a plasma amakwaniritsidwa mkati mwa maola 24-48 ndipo ndi ochepera 1 μg / ml. Malinga ndi kafukufuku, kuchuluka kwambiri kwa metformin m'madzi am'magazi (C max) sikapitilira 5 μg / ml ngakhale ndi mlingo waukulu.

Ndi chakudya chofananacho, mayamwidwe a metformin amachepetsa ndipo pang'ono ndi pang'ono amayamba kuchepa.

Malinga ndi kafukufuku, pambuyo pakukonzekera pakamwa pa mlingo wa 850 mg, kuchepa kwambiri kwa plasma ndende ndi 40%, kutsika kwa AUC ndi 25%, ndikuwonjezereka kwa mphindi 35 pakukwaniritsidwa kwakanthawi. Kukula kwamankhwala kwakusintha kumeneku sikudziwika.

Kugawa. Kumanga mapuloteni a Plasma ndikosatheka.Metformin imalowa m'magazi ofiira. Kuchuluka kwambiri m'magazi kumakhala kocheperako poyerekeza ndi kuchuluka kwa magazi a m'magazi, ndipo kumachitika pambuyo pake. Maselo ofiira nthawi zambiri amayimira chipinda chogawirako chachiwiri. Voliyumu yapakati yogawa (Vd) imachokera ku malita 63-276.

Kupenda. Metformin imachotsedwa mu mkodzo osasinthika. Palibe ma metabolites omwe amapezeka mwa anthu.

Pomaliza Kuvomerezeka kwa aimpso kwa metformin ndi> 400 ml / min. Izi zikuwonetsa kuti metformin imachotsedwanso ndi kusefera kwamadzi ndi kubisalira kwa tubular. Pambuyo makonzedwe, kuchotsa theka moyo ndi pafupifupi 6.5 maola. Mu vuto la impso, kutsekeka kwa impso kumatsika molingana ndi kupezeka kwa creatinine chilolezo, motero kuthetsa theka la moyo kumawonjezeka, komwe kumabweretsa kuwonjezeka kwa plasma metformin.

Type 2 shuga mellitus ndi kulephera kwa zakudya mankhwala ndi zolimbitsa thupi, makamaka odwala onenepa kwambiri:

monga monotherapy kapena kuphatikiza mankhwala molumikizana ndi ena othandizira pakamwa a hypoglycemic kapena molumikizana ndi insulin pochizira akuluakulu.
monga monotherapy kapena kuphatikiza mankhwala omwe ali ndi insulin pochizira ana azaka za 10 ndi achinyamata.

Kuchepetsa zovuta za matenda ashuga okalamba omwe ali ndi matenda a shuga a 2 komanso onenepa kwambiri ngati mankhwala oyambira mzere woyamba wokhala ndi mankhwala osachita bwino.

Kuyanjana ndi mankhwala ena ndi mitundu ina yoyanjana

Kuphatikiza sikulimbikitsidwa.

Mowa Kuledzera kwa pachimake kumayenderana ndi chiopsezo chowonjezeka cha lactic acidosis, makamaka ngati akusala kudya kapena kutsatira zakudya zochepa zopatsa mphamvu, komanso ndi vuto la chiwindi. Mukamachitira ndi metformin, mowa ndi mankhwala okhala ndi mowa ziyenera kupewedwa.

Iodini wokhala ndi zinthu za radiopaque. Kugwiritsira ntchito kwa ayodini mankhwala okhala ndi ayodini zomwe zingayambitse matenda a impso ndipo, chifukwa chake, kuphatikizika kwa metformin komanso chiwopsezo cha lactic acidosis.

Kwa odwala omwe ali ndi GFR> 60 ml / mphindi / 1.73 m 2, metformin iyenera kuyimitsidwa isanachitike kapena mkati mwa phunziroli ndipo sayenera kuyambiranso kupitirira maola 48 mutatha phunzirolo, pokhapokha kuwunikanso ntchito ya aimpso ndikutsimikizira kuti kulibe kuwonongeka kwina kwa impso (onani. .

Odwala omwe amalephera kupezeka ndi aimpso (GFR 45 - 60 ml / mphindi / 1.73 m 2) ayenera kusiya kugwiritsa ntchito Metformin maola 48 asanakonzedwe a zinthu zokhala ndi ayodini ndipo sayenera kuyambiranso kumayambiriro maola 48 mutatha phunzirolo, pokhapokha mutayambiranso ntchito ya aimpso. ndi chitsimikizo cha kusowa kwa kuwonongeka kwa impso.

Kuphatikiza kuyenera kugwiritsidwa ntchito mosamala.

Mankhwala omwe ali ndi vuto la hyperglycemic (GCS of systemic and local action, sympathomimetics). Ndikofunikira kuyang'anira kuchuluka kwa shuga m'magazi pafupipafupi, makamaka kumayambiriro kwa chithandizo. M`kati ndi pambuyo kuchotsa monga olowa mankhwala, m`pofunika kusintha mlingo wa mankhwala.

Ma diuretics, makamaka malupu okodzetsa, amatha kukulitsa chiopsezo cha lactic acidosis chifukwa kuchepa kwa ntchito ya impso.

Zolemba zogwiritsira ntchito

Lactic acidosis ndizosowa kwambiri, koma zovuta za metabolic (kuchuluka kwa kufa kwa anthu osagwiritsidwa ntchito mwadzidzidzi), zomwe zimatha kuchitika chifukwa chakuwala kwa metformin. Nkhani za lactic acidosis zidanenedwa kwa odwala omwe ali ndi matenda osokoneza bongo omwe ali ndi vuto la impso kapena lakuthwa muimpso. Chenjezo liyenera kuchitika pakakhala vuto la impso, mwachitsanzo, ngati mutha magazi (kutsegula m'mimba kwambiri kapena kusanza), kapena kumayambiriro kwa chithandizo cha mankhwala a antihypertensive, okodzetsa, komanso kumayambiriro kwa mankhwala a NSAID. Zikachitika izi, ndikofunikira kuyimitsa kanthawi kochepa kugwiritsa ntchito metformin.

Zina mwamagetsi ziyenera kuganiziridwanso kuti mupewe kukula kwa lactic acidosis: matenda osokoneza bongo omwe samayendetsa bwino, ketosis, kusala kudya kwa nthawi yayitali, kumwa kwambiri mowa, kulephera kwa chiwindi, kapena vuto lililonse lomwe lingachitike ndi hypoxia (mtima wosakhazikika, kulowetsedwa kwapanja).

Lactic acidosis imatha kuwoneka ngati kukokana minofu, kudzimbidwa, kupweteka kwam'mimba komanso asthenia yayikulu. Odwala ayenera kudziwitsa dokotala nthawi yomweyo zomwe zimachitika, makamaka ngati odwala adalekerera kale kugwiritsa ntchito metformin. Zikatero, ndikofunikira kusiya kugwiritsa ntchito metformin mpaka izi zitamveka bwino. Mankhwala a Metformin amayenera kuyambiridwanso pambuyo powunikira phindu / chiopsezo pazochitika zina ndikuwunika ntchito ya impso.

Zizindikiro Lactic acidosis imadziwika ndi kufupika kwa acidic, kupweteka kwam'mimba komanso hypothermia, kupititsa patsogolo kukoma mtima kumatha. Zizindikiro zakuzindikira zimaphatikizapo kuchepa kwa labot mu magazi pH, kuwonjezeka kwa kuchuluka kwa lactate mu seramu yamagazi pamwamba pa 5 mmol / l, kuwonjezeka kwa kusiyana kwa anion ndi chiŵerengero cha lactate / pyruvate. Pankhani ya kukula kwa lactic acidosis, ndikofunikira kuchipatala wodwala nthawi yomweyo (onani gawo "Overdose"). Dokotala ayenera kuchenjeza odwala za chiwopsezo cha kukula ndi zizindikiro za lactic acidosis.

Kulephera kwina. Popeza impformin imachotsedwa ndi impso, ndikofunikira kuyang'ana kuvomerezedwa kwa creatinine (titha kuwerengera ndi kuchuluka kwa creatinine m'madzi a m'magazi pogwiritsa ntchito njira ya Cockcroft-Gault) kapena GFR musanayambe komanso pafupipafupi pa chithandizo cha metformin:

odwala aimpso ntchito - osachepera 1 pachaka,
Kwa odwala okhala ndi chilolezo cha creatinine m'munsi mwa odwala wamba komanso okalamba - osachepera 2-4 pachaka.

Pazifukwa zomwe kulengedwa kwa creatinine

Kuchepetsa aimpso odwala okalamba ndizofala komanso asymptomatic. Chenjezo liyenera kuchitika pakakhala vuto la impso, mwachitsanzo, ngati mutha kuchepa mphamvu kapena kumayambiriro kwa chithandizo chamankhwala a antihypertensive, okodzetsa, komanso kumayambiriro kwa mankhwala a NSAIDs. Zikatero, timalimbikitsidwanso kuyang'anira ntchito ya impso musanayambe chithandizo ndi metformin.

Ntchito yamtima. Odwala omwe ali ndi vuto la mtima ali ndi chiopsezo chachikulu chokhala ndi hypoxia komanso kulephera kwa impso. Odwala omwe ali ndi vuto la mtima wosakhazikika, metformin itha kugwiritsidwa ntchito poyang'anira mtima ndi ntchito yaimpso. Metformin imaphatikizidwa kwa odwala omwe ali ndi vuto la mtima komanso losakhazikika la mtima

Ma ayodini okhala ndi ayodini. Kugwiritsa ntchito kwaukadaulo kwa ma radiopaque othandizira pophunzira ma radiology kungayambitse kulephera kwa impso, ndipo chifukwa chake, kuwerengera kwa metformin komanso chiwopsezo cha lactic acidosis. Kwa odwala omwe ali ndi GFR> 60 ml / mphindi / 1.73 m 2, kugwiritsa ntchito metformin kuyenera kuyimitsidwa isanachitike kapena mkati mwaphunzirolo ndipo kusayambitsidwanso koyambirira kwa maola 48 pambuyo phunziroli, pokhapokha kuwunikanso ntchito ya impso ndikutsimikizira kuti kulibenso kuwonongeka kwa aimpso (onani. gawo "Kuyanjana ndi mankhwala ena ndi mitundu ina (mogwirizana)".

Zithandizo za opaleshoni. Ndikofunikira kusiya kugwiritsa ntchito metformin maola 48 musanachitike opaleshoni yokonzekera, yomwe imagwira ntchito mobwerezabwereza, msana kapena opaleshoni yotsitsimutsa ndipo osayambiranso kupitilira maola 48 mutayamba kugwiritsa ntchito kapena kubwezeretsa zakudya zapakamwa komanso ngati ntchito yachilendo ya impso ikhazikitsidwa.

Ana. Musanayambe chithandizo ndi metformin, kuwunika kwa mtundu wachiwiri wa shuga kuyenera kutsimikiziridwa. Malinga ndi zotsatira za mayeso azachipatala a chaka chimodzi, palibe vuto lililonse la kukula kwa mwana ndi kutha kwa ana lomwe. Komabe, palibe deta pazotsatira za kukula kwa metformin ndi kutha msanga pogwiritsa ntchito metformin, chifukwa chake, kuwunikira mosamala magawo awa kwa ana omwe amathandizidwa ndi metformin, makamaka panthawi yakutha, akulimbikitsidwa.

Ana azaka zapakati pa 10 mpaka 12. Malinga ndi zotsatira za mayeso azachipatala olamulidwa a ana 15 azaka zapakati pa 10 mpaka 12, mphamvu ndi chitetezo cha metformin pagulu la odwala sizinasiyane ndi zomwe zimachitika mwa ana okalamba ndi achinyamata. Mankhwala ayenera kuikidwa mosamala kwa ana azaka zapakati pa 10 mpaka 12.

Njira zina zopewera. Odwala ayenera kutsatira zakudya, kudya yunifolomu yanga tsiku lonse. Odwala onenepa kwambiri ayenera kupitiliza kutsatira zakudya zamafuta ochepa. Ndikofunikira kuyang'anira pafupipafupi zizindikiro za kagayidwe kazakudya.

Metformin monotherapy siyimayambitsa hypoglycemia, koma muyenera kusamala mukamagwiritsa ntchito metformin ndi insulin kapena othandizira ena pakamwa (mwachitsanzo, sulfonylureas kapena meglitinidam.

Gwiritsani ntchito pa nthawi yoyembekezera kapena mkaka wa m'mawere.

Mimba Matenda osagwirizana ndi matenda a shuga panthawi yomwe ali ndi pakati (gestational kapena kulimbikira) amawonjezera mwayi wokhala ndi vuto lobadwa nalo komanso kufa kwa perinatal. Pali zosowa zochepa pakugwiritsa ntchito metformin kwa amayi apakati, sizikuwonetsa chiwopsezo chowonjezereka cha kubadwa kwatsopano. Kafukufuku wamtsogolo sanawonetse vuto pa kutenga pakati, kukulira mluza kapena mwana wosabadwa, kubereka ndi kubereka. Pankhani yakonzekera kukonzekera kutenga pakati, komanso pathupi pathupi, pakulimbikitsidwa kugwiritsa ntchito metformin pochiza matenda ashuga, komanso insulini kukhalabe ndi shuga m'magazi pafupipafupi monga momwe kungathekere, kuchepetsa chiopsezo cha kusokonezeka kwa fetal.

Kuyamwitsa. Metformin imachotsedwa mkaka wa m'mawere, koma palibe zotsatira zoyipa zomwe zimawonedwa mwa akhanda / makanda omwe adayamwa. Komabe, popeza palibe chidziwitso chokwanira pa mankhwalawa, kuyamwitsa sikulimbikitsidwa panthawi ya metformin. Lingaliro loletsa kuyamwitsa liyenera kuganiziridwapo zabwino za kuyamwitsa ndi chiopsezo cha zovuta zoyamwitsa khanda.

Chonde. Metformin sizinakhudze chonde nyama ikagwiritsidwa ntchito mu Mlingo wa 600 mg / kg / tsiku, lomwe linali lokwera pafupifupi katatu kuposa kuchuluka kwa tsiku lililonse kwa anthu chifukwa cha thupi.

Kutha kukopa momwe zinthu zikuyendera mukamayendetsa magalimoto kapena njila zina.

Metformin monotherapy siyimakhudzanso kuchuluka kwa zochita mukamayendetsa kapena kugwiritsa ntchito njira zina, chifukwa mankhwalawa samayambitsa hypoglycemia. Komabe, kusamala kuyenera kuchitika mukamagwiritsa ntchito metformin kuphatikiza othandizira ena a hypoglycemic (sulfonylureas, insulin, kapena meglitinides) chifukwa choopsa cha hypoglycemia.

Mlingo ndi makonzedwe

Monotherapy kapena kuphatikiza mankhwalawa molumikizana ndi ena othandizira pakamwa.

Nthawi zambiri, muyeso woyamba wa 500 mg kapena 850 mg 2-3 kawiri pa tsiku mukamadya kapena mutatha kudya.

Pambuyo masiku 10-15, mlingo uyenera kusinthidwa malinga ndi zotsatira za milingo ya shuga mu seramu yamagazi.

Kuchepetsa pang'onopang'ono kwa mlingo kumachepetsa mavuto kuchokera m'mimba.

Mankhwalawa Mlingo waukulu (2000-3000 mg patsiku) tikulimbikitsidwa kugwiritsa ntchito mapiritsi okhala ndi Mlingo wa 1000 mg.

Mlingo woyenera kwambiri ndi 3000 mg patsiku, womwe umagawidwa pazigawo zitatu.

Pankhani yosintha kuchokera ku mankhwala ena opatsirana, tikuyenera kusiya kumwa mankhwalawa ndikupereka metformin monga tafotokozera pamwambapa.

Kuphatikiza mankhwala osakanikirana ndi insulin.

Kuti akwaniritse bwino kuchuluka kwa shuga m'magazi, metformin ndi insulin zitha kugwiritsidwa ntchito ngati mankhwala osakanikirana. Mwachizolowezi, mlingo woyambira ndi 500 mg kapena 850 mg wa metformin hydrochloride katatu patsiku, pamene mlingo wa insulin uyenera kusankhidwa mogwirizana ndi zotsatira za kuyeza shuga m'magazi.

Monotherapy kapena kuphatikiza mankhwala omwe ali ndi insulin.

Mankhwalawa amagwiritsidwa ntchito kwa ana azaka zopitilira 10 ndi achinyamata. Nthawi zambiri, koyamba mlingo ndi 500 mg kapena 850 mg kamodzi tsiku lililonse panthawi kapena chakudya. Pambuyo masiku 10-15, mlingo uyenera kusinthidwa malinga ndi zotsatira za milingo ya shuga mu seramu yamagazi.

Kuchepetsa pang'onopang'ono kwa mlingo kumachepetsa mavuto kuchokera m'mimba.

Mulingo woyenera kwambiri ndi 2000 mg patsiku, womwe umagawidwa pakawiri.

Kwa odwala okalamba, kuchepa kwa ntchito yaimpso ndikotheka, chifukwa chake, mlingo wa metformin uyenera kusankhidwa malinga ndi kuwunika kwa impso, komwe kuyenera kuchitidwa pafupipafupi (onani

Odwala aimpso kulephera. Metformin itha kugwiritsidwa ntchito kwa odwala omwe amalephera kupweteka aimpso, gawo Sha (creatinine clearance 45 - 59 ml / min kapena GFR 45 - 59 ml / min / 1.73 m 2) pokhapokha ngati pali zovuta zina zomwe zingakulitse chiopsezo cha lactic acidosis, kusintha kwa mlingo wotsatira: mlingo woyambirira ndi 500 mg kapena 850 mg wa metformin hydrochloride 1 nthawi patsiku. Mlingo wapamwamba ndi 1000 mg patsiku ndipo uyenera kugawidwa pawiri. Kusanthula mosamala kwa ntchito ya impso (miyezi itatu iliyonse mpaka isanu ndi umodzi) kuyenera kuchitika.

Ngati creatinine chilolezo kapena GFR amachepetsa

Ana. Mankhwalawa amagwiritsidwa ntchito pochiza ana azaka 10.

Ndi chisamaliro

Pankhani zotsatirazi, kugwiritsa ntchito mankhwalawa ndikololedwa, koma wodwalayo ayenera kuyang'aniridwa ndi dokotala:

kuyamwa
woposa zaka 60
kulimbitsa thupi
zolimbitsa thupi aimpso.

Kuti muchepetse kunenepa, ndikofunikira kutenga Metformin katatu pa tsiku 500 mg kapena 2 kawiri pa tsiku pa 850 mg kwa masabata atatu.

Kuchepetsa thupi

Kuti muchepetse kunenepa, ndikofunikira kumwa mankhwalawa katatu patsiku 500 mg kapena 2 pa tsiku kwa 850 mg kwa masabata atatu. Pambuyo pa izi, yopuma pafupifupi mwezi umodzi uyenera kutengedwa.

Ndikofunikira kuti Metformin yokha siyitsogolera kuwonda, chofunikira ndichakudya cham'mbuyo chamankhwala.

Ndi matenda ashuga

Mlingo woyambirira woperekedwa ndi wopanga matenda a shuga a 2 ndi piritsi limodzi lokhala ndi 500 mg ya metformin katatu patsiku. Kuchulukitsa kwa mankhwalawa kumatheka pambuyo masiku 10-15. Lingaliro loti muwonjezere liyenera kukhazikitsidwa pazotsatira za kuyezetsa magazi kwa shuga. Mulingo wovomerezeka wa tsiku ndi tsiku ndi 3 g, muyezo wowonjezera wowerengeka ndi 1.5-2 g. Kuchulukana pang'onopang'ono kwa kuchuluka kwa mankhwalawa ndikugawika mu Mlingo wachiwiri wa 2-3 ndikofunikira kuti muchepetse kusokonezeka kwa njira yogwirira ntchito.

Mlingo wophatikizira wa insulin umasankhidwa payekhapayekha kuti azikhala wathithithi shuga. Kuchuluka kwa Metformin kumakhalabe chimodzimodzi ndi monotherapy

Mlingo wophatikizira wa insulin umasankhidwa payekhapayekha kuti azikhala wathithithi shuga.

Matumbo

Pa gawo loyamba la chithandizo nthawi zambiri pamabuka:

nseru
kutsegula m'mimba
kupweteka m'mimba
kuchepa kwamtima.

Zizindikiro izi nthawi zambiri zimazimiririka zokha pamene thupi lizolowera mankhwalawo.

Zokhudza mphamvu pakuwongolera njira

Metformin monotherapy sikukhudza kuthekera koongolera njira. Mukatengedwa molumikizana ndi ma hypolytics ena, kukula kwa hypoglycemia ndikotheka, kutsatsa kuchepa kwa ndende ndikuvuta pakugwiritsa ntchito njira.

Metformin monotherapy sikukhudza kuthekera koongolera njira.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Ngakhale umboni kuti mankhwala omwe ali ndi mankhwalawa samachulukitsa chiopsezo chakukukula kwa mwana wosabadwayo, amayi apakati amawonetsedwa m'malo mwake ndi insulin.

Metformin hydrochloride imatha kulowa mkaka wa m'mawere; palibe deta yodalirika yokhudza chitetezo chatsopano cha akhanda. Chifukwa chake, ngati kuli kotheka, ndikulimbikitsidwa kusiya kudya.

Gwiritsani ntchito mu ukalamba

Mukakalamba, mwayi wokhala ndi kulephera kwa impso, womwe umatha kukhala asymptomatic, ukuwonjezeka. Chifukwa chake, ndikofunikira kusankha mankhwalawa ndikuwathandizira nthawi zonse, kuwunika momwe gululi limagwirira ntchito.

Mukakalamba, mwayi wokhala ndi kulephera kwa impso, womwe umatha kukhala asymptomatic, ukuwonjezeka.

Mankhwala ochulukirapo a Metformin Zentiva

Mankhwala osokoneza bongo a metformin hydrochloride angayambitse kukulitsa kwa zinthu monga lactic acidosis ndi kapamba. Zikaonekera, mankhwalawo ayenera kusiyidwa. Pochotsa mwachangu zomwe zimachitika m'thupi, hemodialysis akuwonetsedwa. Syndrome dalili zimalimbikitsidwanso.

Mankhwala osokoneza bongo a metformin hydrochloride angayambitse kukulitsa kwa zinthu monga lactic acidosis ndi kapamba.

Kuchita ndi mankhwala ena

Kuphatikiza ndi ayodini wokhala ndi zinthu za radiopaque ndizotsutsana. Pochita mankhwala ndi Metformin, kugwiritsa ntchito mankhwala okhala ndi ethyl mowa osavomerezeka. Kuyang'anira bwino shuga ndi / kapena ntchito ya impso ndikofunikira mukaphatikizidwa ndi zinthu monga:

Danazole
Chlorpromazine
glucocorticosteroids,
okodzetsa
estrogens ndi mahomoni a chithokomiro,
bta2-adrenomimetics mu mawonekedwe a jakisoni,
mankhwala opangidwa kuti achepetse kuthamanga kwa magazi, kupatula ACE inhibitors,
aracbose,
zochokera sulfonylurea,
salicylates,
Nifedipine
Mao zoletsa
Ibuprofen ndi ena NSAID
Morphine ndi mankhwala ena a cationic.

Kugwiritsa ntchito limodzi ndi mankhwalawa kungafune kuti musinthe mlingo wa Metformin.

Kuphatikiza apo, Metformin imachepetsa mphamvu ya Fenprocumone mankhwala.

Pochita mankhwala ndi Metformin, kugwiritsa ntchito mankhwala okhala ndi ethyl mowa osavomerezeka.

Kuyenderana ndi mowa

Zomwe zimagwiritsidwa ntchito mankhwalawa sizigwirizana ndi ethanol.

Analog ndi mankhwala aliwonse okhala ndi metformin hydrochloride kuchokera kwa opanga osiyanasiyana, monga:

Aigrichterter,
Izvarino Pharma,
Akrikhin,
LLC "Merk",
Canon Pharma Production.

Mankhwala osokoneza bongo amatha kukhala ndi mayina osiyanasiyana ogulitsa, mwachitsanzo Glucofage kapena Siofor.

Kodi pali kusiyana kotani pakati pa Metformin ndi Metformin Zentiva

Kusiyana pakati pa Metformin Zentiva ndi Metformin ndi kampani yamapiritsi. Palibe kusiyana muyezo kapena mankhwala.

Ndemanga za Metformin Zentiva

Galina, yemwe ali ndi zaka 25, ku Moscow, anati: "Ubwino wa Metformin ndikuti ndi koyenera ngakhale pochiritsa mwana. Chofunikira kwambiri ndicho kudzifufuza moyenera musanayambe mankhwala. ”

Svetlana, endocrinologist, wazaka 47, Tyumen: "Ndimaona Metformin ngati mankhwala othandiza pa hypoglycemic. Komabe, ngakhale ndimadziwika kuti ndi njira yochepetsera kunenepa, ndili ndi chitsimikizo kuti mankhwalawa amayenera kumwa okhawo omwe amapezeka ndi matenda a shuga, ndipo ndibwino kuchepa thupi mothandizidwa ndi masewera komanso zakudya. "

Gulnaz, wazaka 26, a Kazan: "Wodwalayo adalangiza kugwiritsa ntchito mankhwala okhala ndi Metformin kuti achepetse chilakolako cha kudya. Analimbikitsa kugula zinthu za wopanga, ponena kuti amadalira mtundu wake ndi mbiri yake. Ndine wokondwa kuti ndinatsatira uphungu wake. Kufunika kwa chakudya kwatsika kwambiri. Sindinazindikire kuti mankhwalawo ayamba. ”

Zotsatira zoyipa

Nthawi zambiri zoyipa kumayambiriro kwa chithandizo cha mseru, kusanza, kutsegula m'mimba, kupweteka kwam'mimba, kusowa kwa chilimbikitso. Zizindikiro zambiri nthawi zambiri zimakhala zokha. Pofuna kupewa kupezeka kwa zotsatirazi, kuwonjezereka kwapang'onopang'ono kwa mlingo komanso kugwiritsa ntchito mlingo wa tsiku ndi tsiku mu 2-3.

Zotsatira zoyipa zomwe zimachitika pafupipafupi zimagawidwa m'magulu otsatirawa:

nthawi zambiri (> 1/10), nthawi zambiri (> 1/100 ndi 1/1000 ndi 1/10000 ndi zidziwitso Amvera

Ndemanga zoyipa

Ndinatenga American Combogliz Prolong .. chabwino .. mu 205 Moscow polyclinic, endocrinologist amasintha mankhwalawo ndikulembera Russian Formetin ndikuyamika ... ndipo madzulowo ndimayenera kumwa piritsi lina ... NDINAYESA piritsi mwachidule ... ndinayesa shuga 8.6 ... ndimadikirira maola angapo kuti ndichepetse kuchepa ndi zidayamba ... chiwindi chidaphulika ... ndipo pomwepo miyala yaying'ono idayamba kuyenda ... nseru idayamba ... ululu ... panali thukuta lokomata pathupi langa lonse ... kunjenjemera ... chitsenderezo chidakwera ndipo shuga idakwera mpaka 12.6 ndikuwukira kwa angina ... ngakhale kuti kugunda kwamtima kudali kale mu 2016 chaka .. Ambulansi .. kukonzanso i .. .. stenting ... Tsopano ndikugula ndalama zanga kuchokera penshoni ya Combogliz Kuonjezera ma ruble 4.500. ndipo mutatha kununkha, tengani chaka cha Brilint ma ruble 5.500 ... osawerengetsa 2000 ma statins ... .. Mankhwala osayipidwa okhala ndi zotsatira zoyipa ... sindipangira izi kwa aliyense!

Anandiwuzanso kumwa metformin chifukwa chakukwera kwa shuga m'magazi, madotolo onse amandilangiza pa TV komanso pa intaneti, amayamika aliyense.Ndinamwa masiku 10, mankhwalawa mwina anali ndi diuretic, chifukwa amayendetsa tsiku pang'ono. Usiku. Ena ali ndi ziwengo zotayirira, zida zawo zimawonekera pamenepo. Pa tsiku lakhumi mtima wanga unayamba kugunda, mtima wanga unasokonekera, kuthamanga kwa magazi, kunayamba kuzizira kwambiri, sindinagone usiku ndipo ndikadapulumuka, sindikadapulumuka. adandipatsa theka piritsi la concor, piritsi limodzi la equapril kukakamiza, aspirin.asp zotupa ndi mavitamini ndi michere yambiri. Pofika m'mawa zidakhala bwino. Sindimwanso kumwa ndipo sindimalangiza aliyense. Shuga nthawi zambiri amadzuka mpaka 7 m'mawa. Zikuwoneka ngati kuti amapha anthu, mwina ndiwothandiza kwa wina. Kulibwino osadzipangitsa kukhala onenepa kwambiri, zochita zolimbitsa thupi zambiri, ufa wocheperako komanso wokoma.

Chifukwa patatha masiku atatu palibe zotsatira zilizonse

Metformin ndi mankhwala omwe, kuphatikiza pakuvulaza thupi, samabweretsa chilichonse. Kodi mungayike bwanji chinthu china chomwe thupi limatsutsa ndikulimba chifukwa chakupha. Werengani kuti muwone zovuta zomwe amakumana nazo pa anthu. Mankhwalawa amalepheretsa kuchulukana kwa glycogen m'chiwindi, ndipo ndiye gwero lalikulu lamphamvu kwa minofu. Wowonongera mphamvu ndi kugona. Odwala, kutsegula m'mimba ndi bwato wina. Samachiritsa, koma wolumala. Zomwe gehena ndikupanga moyo, koma mankhwalawa atha kukupangani osavomerezeka. kuposa kuchiritsa kena kake.

Mankhwala Metformin "Glucofage" - Metformin ndi mawonekedwe ake - bomba pamimba

Zotsatira zake za kumwa mankhwalawa ndi matenda opatsirana m'matumbo onse.

Adatenga glucophage, kwa miyezi 4 adataya makilogalamu 19. Koma tsopano patatha zaka 12 nditadwala matenda a kapamba, chifuwa chachikulu cha m'mimba, komanso matenda am'mimba. Mwambiri, mankhwalawa ndi bomba chabe pakudya m'mimba. Dokotala wa gastroenterologist adatsimikiza kuti mankhwalawa ndi omwe adayambitsa matenda anga. Chifukwa chake muyenera kuganizira mosamala musanatenge. Ngakhale mankhwalawo adandilamula ndi adokotala, endocrinologist, ndipo ndidatsata kudya. Ndipo kulemerako kunabweza zaka 5 kubwerera.

Ndimatenga metformin 850 monga adanenera adotolo kuti azikhala ndi masewera olimbitsa thupi. Ndimachita masewera olimbitsa thupi, ndimakonda kudya, nthawi zina sindimadya maswiti, nthawi zina maswiti awiri, makeke ndi tiyi. Koma tsopano pali mphesa zambiri kunyumba - nthawi zina ndimadya burashi yaying'ono. Kuthamanga shuga 5, 7-6, 1 osakwezeka. Koma panali vuto lalikulu - kutsegula m'mimba ndi dzino ndi ilo. Zosasangalatsa komanso zosasangalatsa. Kuwona loperamide tsopano ndimamwa neosmectin (wolemba wothandizira). Ndimangotenga ma NSAIDs-melaxics, zimawoneka kuti ndizovulaza. Ndiuzeni, chonde, ndichani ndi choti ndikatenge? Tilibe endocrinologist m'derali.

Ndili ndi matenda ashuga, zikomo Mulungu, ayi. Komabe, kuyambira ndili mwana ndimakonda kukhala wonenepa kwambiri. Nditangomenya nkhondo, ndidazungulirazungulira. Mnzanga wapamtima ndi dokotala wanga. Komanso chubby. Nthawi ina adanena kuti tsopano tidzamwa Metformin kuti muchepetse thupi. Palibe chifukwa chokhulupirira, adayamba kumwa piritsi tsiku. Patatha mwezi umodzi, ndinaponyera, sizikugwira ntchito kwa ine, ndinali kudwala ndipo mutu wanga ukupindika. Koma mnzake adapulumuka, ndimamwa kwa miyezi isanu ndi umodzi, ndipo kulemera kwake kunachepa pang'onopang'ono ndi m'malovu. Zotsatira zake, idatsika ndi 9 kg. Matenda a shuga nawonso si odwala. Palibe vuto, sindilangiza aliyense, ngakhale dokotala mwiniyo adagwiritsa ntchito njira iyi, ndimangogawana nawo ntchito yogwiritsira ntchito metformin.

Ndimakhala ku Germany. Anamwanso metformin chaka chapitacho. Tsoka ilo sanandithandizire, shugayo amabwereranso mwakale, koma mimba sinabwere. Ndinaleka kumwa mankhwalawa chifukwa panali zovuta zina. Koma lingaliro la adotolo linali: kumwa mpaka mutakhala ndi pakati, monga momwe ndimaonera mikwingwirima iwiri ikutsika. Palinso njira zina zomwe zimathandizira kuti munthu akhale ndi prediabetes komanso panthawi yomwe ali ndi pakati siipatsidwe. Mwachitsanzo inofert. Cinnamon imatsitsanso shuga bwino. Zowona, muyenera kumamwa mosamala. Zitha kuyambitsa mamvekedwe. Mwambiri, ndikuganiza kuti palibe chifukwa chomvera momwe ziliri kunja.

Ndikudwala matenda ashuga, kwa pafupifupi zaka 20 - pakadali pano - ndimatenga Metformin ndikubaya insulin - Novo Sakanizani 30 Flex Pen - jekeseni kwa miyezi 6 - 6 magawo. - sizithandiza. Masabata 2 apitawa, anawonjezera - 2 mayunitsi. ndipo tsopano ndimabaya - mayunitsi 8. koma ndikadumphira pachakudya, sindimadya. Ndikuchita bwino. Shuga - kwenikweni osachepetsedwa - choti achite. ? Zikomo

Ndinkamwa miyezi 5, monga adanenera dokotala kuti ndichepetse thupi. Sindinataye gamu, ndinapereka magazi ndipo ndinadzidzimuka chifukwa chakudya cha ***** shugayu (chidali pachiwopsezo chotenga 4. 8, miyezi 3 mutangomaliza kumwa 6. Ma TSH mahoni apamwamba kwambiri kuwirikiza kawiri kuposa kale, uric acid m'magazi imakhala yokwanira kuwirikiza kawiri kuposa kale, sindinamalize nthawi yoikika, nditatha mwezi ndimapereka magazi - chilichonse ndichabwino.

imathandizira kuthamangitsa njira za metabolic ndipo imatsogolera pakuwonongeka kwa kilogalamu

Mankhwalawa adagwiritsidwa ntchito ndi agogo anga ngati mankhwala omwe anali m'gulu la zovuta zochizira matenda ashuga. Chowonadi ndi chakuti agogo anga ndi amayi onenepa kwambiri ndipo madotolo adada nkhawa ndi thanzi lawo pankhaniyi.

Ndipo pokhapokha ndidaphunzira kuti mankhwalawa amatha kukhudza kagayidwe kenakake ndipo amathandizira kuchepetsa kuchepa kwa thupi chifukwa chazomwe zimapangitsa kuti magayedwe am'mimba azigwira komanso kuthamanga kwa kagayidwe.

Ndine pano, monga wokonda kwambiri zakudya ndipo ndimatanthauzidwe amomwe ndimataya amafuta, ndidaganiza zondichitikira ndekha. Ndinagula phukusi la mankhwalawo ku pharmacy, mwa njira, mtengo wake unawoneka kwa ine wokulirapo. Ndinawerenga zambiri za mankhwalawo mu malangizo oti agwiritse ntchito ndipo ndidaganiza zodzatenga molingana ndi izo.

Masiku angapo pambuyo pake ndinamva kudzuka kwamphamvu. Ndinkachita nseru, koma osati monga zimakonda kupezeka poyizoni, koma ndimangokhala wowuma ndipo panali malingaliro osalimba ofooka, opweteka m'thupi langa lonse.

Ndasiya kumwa mapilitsiwa ndipo sindikulimbikitsa kuti aliyense amwe ndi iwonso.

Ndemanga zopanda ndale

Mankhwala Metformin "Glucophage" - Nusea, kutsekula m'mimba komanso kusowa kwa chilakolako chothandizira kumachepetsa thupi

kutaya thupi kwambiri
kusowa kwa chakudya

Glucophage Ndinaganiza zoyesa kutaya mtima. Kwa nthawi yayitali ndidayesera kuchepetsa thupi pazakudya ndi masewera osiyanasiyana. Palibe chomwe chinandithandiza. Munthawi yatsopano kwambiri, ndikuyang'ana piritsi lozizwitsa, ndinakumana ndi Glucophage. Za iye adalemba atsikana akuyesera kutenga pakati, adamupatsa mayankho a ovary polycystic. Ndipo aliyense analemba kuti, kuphatikiza zina zonse, amachepetsa thupi.

Ndinapita kukasokosi ndipo ndinkaganiza kuti sangandigulitse popanda mankhwala. Koma sanafunse za chinsinsi.

Pafupifupi maola awiri nditamwa mapiritsi, ndidadwala kwambiri. Mapeto ake, nseru izi zidatha kusanza. Koma sizinali zokhazo, ndiye kuti m'mimba mwanga mwapendekeka. Masana, ndimathamangira kuchimbudzi. Zowona, izi zinali zophatikiza - sindinkafuna kudya konse, sindinkakumbukira za chakudya.

Nditaphunzira malangizowo, ndinazindikira kuti ndiyamba ndi mlingo waukulu kwambiri. Zinafika kuti izi zikuyenera kuchitika pang'onopang'ono, pakupita milungu ingapo.

Zotsatira zake, ndinachepa kwambiri. Koma nthawi yonseyi, nseru sizinasiye, monganso m'mimba. Panalibe chikondwerero ayi, ndinazikonda kwambiri.

Ndinafuna kuchepetsa thupi pogwiritsa ntchito mapiritsi awa. Kuyambika pambuyo pamahomoni. Pazonse, chidwi changa cha insulin chimachepetsedwa, chifukwa ndimatha kudya maswiti ambiri. Kuphatikiza apo, ndinawerenga kuti zimathandiza kutenga pakati kwa iwo omwe ali ndi PCOS. Zachidziwikire, sindinapatsidwe dokotala, koma adokotala sanali aluso kwambiri. Pazonse, adawononga moyo wanga pang'ono - koma iyi ndi nkhani ina. Ndinkatsatira zakudya zopanda ufa - zotsekemera - zonona, zonenepa, zolimbitsa thupi katatu pa sabata. (ntchito zapakatikati) ndipo palibe zomwe zasintha. Poyamba, ndinali wopanda nseru pang'ono, ndiye kuti zonse "zinakhazikika." Ndinkamwa pafupifupi mwezi .. -1 kilo, motero zimandichitira pophunzira komanso kudya. Zachidziwikire, ana nawonso sanawonekere :) Mwambiri, kwa ine, chozizwitsa sichinachitike. Pali chimodzi kuphatikiza kwa ine - poyambira simumva bwino kwambiri, koma kenako mumazolowera. Atsikana, ngati wina akudziwa zinsinsi - gawani. Werengani za zomwe ndakumana nazo pakuwunika kwanga.

Kanemayo angathandize kudzikoka ndekha - Ndikuyiyikira kwambiri. Chitanipo kanthu nthawi yomweyo.

Tin, kumwa Glucophage kwa masiku 20. Tsopano nthawi theka. Ndataya 2 kg yokha. Sindikudziwa ngati ndikupitiliza kumwa. Zotsatira zake ndizochepa kwambiri. Sindikulangizani.

Ndinaganiza z kumwa Metformin kuti muchepetse thupi, chifukwa amati imaletsa chakudya. Ndinkamwa mogwirizana ndi malangizo, pang'onopang'ono ndikuwonjezera muyezo. Ndiyenera kunena nthawi yomweyo kuti sindimadwala matenda ashuga kapena matenda aliwonse kuti ndizinena motsimikiza. Ndipo, zoona zake, sindinazindikire zotsatira pambuyo pa mwezi umodzi. Winalemba kuti ali ndi zovuta zake, kuti mutha kudwala ngati mumamwa osapangana naye. Chilichonse chinali bwino ndi ine, kapena m'malo mwake, mwanjira iliyonse - kuti ndinamwa zomwe sindinachite. Mwina ili ngati mankhwala, koma kuchepa thupi - 0. Chifukwa chake sindinganene motsimikiza kuti ndiyenera kutero kapena ayi. Koma pofuna kuchepetsa thupi, ayi.

Mu zovuta mankhwala

Metformin ndi mankhwala apadera. Wogwira ntchito ali ndi dzina lomweli - metformin. Ndi gawo la mankhwala ambiri, mwachitsanzo, "Glucophage" yomweyo. Nthawi zambiri amalembera endocrinologists kapena gynecologists kuti achulukitse kagayidwe. Wophunzira za endocrinologist adamupangira iye.

Mlingo wa Metformin amasankhidwa payekha. Ndinkamwa piritsi 1 patsiku nditatha kudya m'mwezi woyamba, ndi mapiritsi awiri patsiku kwa miyezi itatu. Sabata yoyamba panali mbali yamphamvu - nthawi zambiri imathamangira kuchimbudzi, ndikusunthidwa pang'ono. Zosasangalatsa, kumene. Kenako zonse zidabwezeretsa ndikumwa popanda kumwa mopitirira muyeso.

Anandipatsa Metformin mu zovuta mankhwala, chifukwa sindinganene motsimikiza kuti mankhwalawa adandithandizanji.

Metformin, glucophage kapena siofor (chinthu chomwecho) ndi mankhwala omwe amaperekedwa kwa anthu odwala matenda ashuga, ndipo insulini komanso osapatsa insulin amaletsedwa.

Mwa munthu aliyense (kuphatikiza wathanzi), atadya chakudya, kuchuluka kwa glucose m'magazi kumawonjezeka. Kukwera kwa glucose okwanira, komwe kumapangitsa insulini yambiri kutulutsa. Insulin imachepetsa kuchepa kwamafuta ndipo imalimbikitsa kaphatikizidwe wamafuta acids, motero imapangitsa kukula kwamafuta amthupi.

Ndipo metformin, glucophage ndi siofor, kutsitsa glucose pambuyo podya, kuchepetsa kuchuluka kwa insulin yomwe imatulutsidwa poyankha, komanso kupewa zovuta zambiri za matenda ashuga.

Komanso mankhwalawa amatha kugwiritsidwa ntchito ndi anthu omwe akufuna kuchepa thupi. Ndikwabwino kuphatikiza zotsatira za metformin, glucophage ndi siofor ndi zakudya zama carb ochepa komanso masewera olimbitsa thupi. Pankhaniyi, zotsatira za metformin zidzakulanso

Komabe, zingakhale bwino kufunsa adotolo ngati mungathe kapena ayi. Izi zimapangidwa kuti muchepetse shuga, koma osafunikira kwenikweni. Osati kwenikweni pa endocrinologist, akatswiri azachipatala komanso azachipatala amadziwa zonse za mankhwalawa omwe amalola kuti musamete.

Aliyense ali ndi zotsatira zosiyana, pali omwe amathandizira kuti achepetse thupi, ndipo pali iwo omwe ali ngati "nkhuku yakufa."

Mayankho abwino

Mankhwala Metformin "Glucophage" - Kuchepetsa thupi, koma okhawo omwe ali ndi vuto la kapamba

Titha kusokoneza
kusowa kwa chakudya.

Mankhwala ndiwofunika, ayenera kugwiritsidwa ntchito mwanzeru komanso mokhazikika pokhapokha ngati akuwuzani. dokotala. Anandipeza ndimatenda a insulin (vuto lomwe limayambitsa matenda a shuga 2), ndipo adandiuza kuti amwe glucophage. Ndinayamba kuchepa thupi makilogalamu awiri pamwezi, izi ndizochepa, koma mafuta adasiya mbali, pamimba, ndi achule. kupepuka kunayamba kumva thupi lonse. Mankhwalawa adandithandiza kuti ndikwaniritse mafomu ofunikira, ndakhuta. Koma ndikwabwino ngati mukufufuzidwa matenda anu (mtundu 2 wa matenda ashuga), ndiye ichi ndi mankhwala. Madokotala ochokera padziko lonse lapansi akuti 90% ya anthu onenepa kwambiri amatsutsa insulin. Glucophage imathandizira kuti Oraginism ichite bwino mafuta osokoneza bongo osanenepetsa kwambiri.

Ndili ndi mbiri yosauka yabanja ya matenda ashuga. Nthawi ndi nthawi ndimayeza shuga osati kalekale, mkati mwa kupsinjika, chizindikiro chimakhala 6, 5. Sindinganene kuti ndimadya ufa kapena wokoma. Palibe chilichonse chotere ndipo kuchuluka kwa shuga kwanditeteza, makamaka nditazindikira kuti sizinali ngozi. Kwenikweni, ndidayamba kuyeza shuga nditazindikira kuti ndatopa kwambiri, ndimakwiya nthawi zonse ndi kena kake ndikufuna kugona.

Ndinakumbukira kuti amayi anga anali mokhazikika. The endocrinologist adandimvera, adayang'ana mayesowo ndipo adandiuza kuti ndisinthe moyo wanga pang'ono, ndiyende nthawi yayitali, ndikuyamba kudya. Nthawi yomweyo, Mankhwala a Metformin adandilimbikitsa. Zimalimbikitsa kumangiriza kwa insulin kwa ma receptors.

Poyamba ndidayenera kumwa mapiritsi usiku, kenako piritsi limodzi m'mawa, lachiwiri madzulo. Osati wopanda mavuto. M'mimba mwanga mudadwala ndipo mudadwala matenda oyamba m'masiku oyamba kulowa.

Mkhalidwe wofananira unasinthidwa mwachangu kwambiri. Kutopa ndi kugona zidapita. Sindinganene kuti chidwi chosintha, mwina chayamba kuchepa, sindikudziwa. Mlingo wa shuga unabweranso mwakale. Dotolo adati ziyenera kutengedwa mpaka kulemera kumatsika, ngakhale ndilibe ndalama zowonjezera. Mankhwalawa sanakhudze kwambiri kulemera kwanga. Itha kukhala kuti yayandikira mu kugwa, sindikudziwa.

Mwambiri, ndikuganiza kuti mankhwalawa amandithandizira bwino. Zotsatira zoyipa zidapita mwachangu.

Njira yotsika mtengo komanso yabwino kwambiri kwa iwo omwe ali ndi boma la matenda ashuga. Shuga yanga pamimba yopanda kanthu inali yofanana ndi mayunitsi 5, atatu, ndipo panali zovuta zamafuta - zakudya komanso masewera olimbitsa thupi adathandizira pang'ono, ndipo ndinayamba kulemera mwachangu komanso mosavuta. Kunapezeka kuti ndinali ndi insulin, chifukwa sindikanatha mapiritsi. Sindinganene kuti zotsatira zake zinali pomwepo - shuga wanga anali kuchepa, koma pang'onopang'ono. Kumbali ina, timafuna nthawi zonse mwachangu, koma, kutsika kwambiri kwa shuga kumakhalanso koopsa, motero ndibwino kukhala oleza mtima. Ndinauzidwa kuti ndizimwa Metformin kwa miyezi isanu, ndipo nditatha miyezi 4, shuga anali kale ndi zigawo 4, - kwa ine, ndi zotsatira zabwino. Chachikulu ndikuti mankhwalawa atatha, amakhalabe, shuga adakwera pang'ono (4, 5 tsopano), koma sipanakhale kusintha kwakukulu m'miyezi isanu ndi umodzi, monga mukuwonera. Nditamwa mankhwalawo, ndidataya makilogalamu 19, 2 - kwa ine, kungoyambira zongopeka, kulemera komwe ndidatsala nako monga momwe ndimapezera. Ndinasiyanso chilakolako chofuna kudya pamene ndinangodya, ndipo ndikufunanso, chifukwa tsopano ndilibe mwayi wonenepa.

Ndili ndi matenda ashuga a 2. Ndakhala ndikutenga Metformin kuphatikiza jakisoni wa insulin kwa pafupifupi chaka. Mankhwalawa amachepetsa shuga m'magazi, posachedwa ndidasokonezeka kwakukulu ndikupereka insulin. Masabata awiri adayenera kutenga "Metformin" imodzi ndipo adandisangalatsa ndi ntchito yake yabwino. Ndipo ndilinso ndi matenda a chiwindi, pankhaniyi, ndidaphunzira malingaliro a dotolo momwe Metformin amakhudzira chiwindi changa chodwala. Anandisangalatsa, akunena kuti zonse zili m'dongosolo, musataye mtima - zilibe tanthauzo. Mwambiri, ineyo pandekha ndimakondwera ndi mankhwalawa. Koma anthu onse ndiosiyana ndipo thupi la aliyense ndi losiyana kotero yang'anani, lingalirani, funsanani ndi madokotala.

“Ndimawagwiritsa ntchito odwala matenda ashuga a 2 ndipo ndimagwiritsa ntchito metformin nthawi zonse. Nthawi ina, woganiza kwambiri za udindo wake popewa kukalamba. Koma ndidasankha kusankha njira zachilengedwe. Mwa zochitika zaposachedwa, ndikukumbukira mzimayi wazaka 45 yemwe adavutika kwa nthawi yayitali chifukwa chokhala wonenepa kwambiri (30 makilogalamu atakhala ndi pakati pa 37). Cholinga chachikulu pa phwando ndikuthandizira kuchepa thupi. Kafukufukuyu adawonetsa zizindikiro zosasangalatsa zomwe sanazindikire kuti anali ndi nkhawa. Kupenda kunawonetsa kulolerana kwa glucose. Inde, metformin idakulitsa mkhalidwe wake, kulemera kunayamba kutsika. Koma sindimawona kuti uku ndi mwayi wapadera wa mankhwalawa. Zomwe zimatsogolera pakupambana zinali zakudya. Wodwalayo anachita mantha kwambiri ndi mavuto azovuta azaumoyo ndipo mogwirizana ndi zomwe analangizidwa. ”

Ngakhale, zowona, pakadali pano palibe mankhwala otsika mtengo. Ndinatenga Metformin nthawi imodzi pamene shuga yanga inakwera kufika pa 6. 5. Zinali zaka zingapo zapitazo. Sindikumvetsa bwino chifukwa chake izi zinachitika. Kenako adadzifotokozera nthawi yachilimwe komanso nthawi yovuta. Ngakhale, zoona, ndili ndi chiyembekezo cha matenda ashuga.

Zakudya sizimakhalanso ndi chakudya chamafuta ambiri, koma chifukwa cha tsiku lomwe amagwira ntchito amuna anga, ndimakonda kudya usiku. Amabwera mochedwa ndipo kwa nthawi yayitali pansi pa kompyuta ndipo TV imadya mosangalala. Perforce, inenso ndikufuna, chabwino, ndimakhala pansi ndikampani. Ndinayamba kuwona kuti ndili ndi kufooka kosalekeza, ndimafuna kugona nthawi zonse, ndilibe mphamvu zochitira chilichonse, ndimasintha chilichonse ndi maso anga, komanso kutuluka pampando kuti ndikasankhe zochita mwamphamvu. Zinapezeka mwangozi kuti shuga amakwezedwa, kuphatikiza apo, mopitilira komanso mosasamala zomwe ndidadya usiku komanso nthawi yanji.

Kenako ndidayamba kutenga Siofor - iyi ndi metformin yomweyo, koma imawononga ndalama zambiri. Mankhwala amalimbikitsa kuyanjana kwa shuga ndi ma receptors, omwe pazifukwa zina amasiya kuzindikira monosugar iyi. Thandizo linabwera pafupifupi nthawi yomweyo. Ndinkawona kuti mphamvu zanga zikuchulukirachulukira, ndidayamba kupitilirabe zochulukira, kusinthika kwanga kudakulanso. Ndinkamwa paketi, kenako kukwera kwamtengo kumalowa ndipo ndidayang'ana intaneti ndikufufuza ma analogi a Siofor otsika mtengo. Pali zambiri za izo. Kenako ndidagula metformin ndikuyamba kutenga. Sindimamva kusiyana.

Tsopano ndikuvomereza, koma kawirikawiri, kufooka kukapitanso, ndimamwa kwa masiku angapo. Shuga adafufuza kangapo - pamalire a chizolowezi, madotolo adalibe madandaulo. Sanatchulidwe kwa endocrinologist. Ponena za metformin - amakhulupirira kuti mankhwalawa kuti apititse patsogolo moyo wina pambuyo pa zaka zinazake ndizofunikira kuti aliyense amwe.

Ndekha, ndinapanga malingaliro angapo. Zachidziwikire, mumafunikira chakudya, simungathe kuchita popanda icho. Tsopano ndimayesa chilichonse chokoma kapena chakudya, ngati ndikufunadi kudya theka loyamba la tsiku. Pambuyo 12, mosafunikira popanda ufa, ngati ndikufuna lokoma - 70% chokoleti kuti chithandizire .. Masamba ndibwino kudya zosaphika, ngati zingatheke. Sindinawachotsere mbatata pachakudya changa. Ndimaphika biringanya ndi zukini mpaka ataphika theka - ngakhale, ngakhale atapatsidwa ntchito, amakhalabe ndi fiber, ngakhale shuga amawonjezeredwa. Madzulo, abambo anga akabwera kudzakhala pansi kuti adye, ndimayesetsa kuchita bizinesi ina kuti ndisasokonezedwe kapena, ndikakhala pansi, ndimadya masamba kapena nyama mosinthanitsa.

Komabe, kuti muchepetse kuchuluka kwa glucose kukula, muyenera kusunthira kwambiri. Ndimayesetsa kuyenda kwambiri, nthawi zina ndimapita mu dziwe - thanzi langa likukula bwino. Eya, metformin imakhala pafupi kwambiri. Pa zisonyezo zoyambirira za kuchuluka kwa shuga, ndimayamba kutenga, kusanthula, zomwe zidapangitsa kuti ndikhale ndi kusintha machitidwe anga. Popanda metformin, zingakhale zovuta kwambiri kuchita, chifukwa imakhala bwalo loipa: kufooka - kamodzinso kosafuna kuyenda kwambiri - kusinthasintha ndikulimba - ndikukhazikika pamenepo - kufooka. Ndipo apa zikuwoneka kuti akumwa mankhwalawo ndipo kufooka kumachoka ndipo chisangalalo chimakwera. Ndipo mphindi 20 poyenda ndi kuyamba kuyenda msanga sikuwoneka wowopsa panonso.

Mankhwala abwino a shuga

Sindikudziwa zomwe anthu omwe akufuna kuchepetsa thupi ndi mankhwalawa akuyesera kukwaniritsa. Kuchepetsa thupi sikuwoneka bwino. Mankhwalawa cholinga chake ndi kuchiza matenda ashuga. Inde, kukonza kagayidwe kazakudya, mankhwalawa amathandizira kuwonda, koma ngati mutsatira zakudya. Koma pankhaniyi, popanda mankhwalawa, zotsatira zake zidzakhala chimodzimodzi. Koma chakuti kuigwiritsa ntchito popanda chifukwa kumatha kuvulaza thanzi, palibe amene angaganizirepo. Itha kukhala itapha. Koma izi zimachitika pokhapokha ngati sizikugwiritsidwa ntchito monga momwe dokotala wakunenera. Ndipo kusankhidwa kwake ndi muyezo - matenda ashuga. Komanso, ngakhale ali ndi matenda oopsa, amawayang'anira, mosiyana payekhapayekha.

Mwachitsanzo, amayi anga ali ndi matenda ashuga a 2. Amangotenga nthawi yonse akungolira. Koma nthawi idafika ndipo adasiya kuthandiza. Madokotala adalimbana kwa nthawi yayitali, kuyesera kuchepetsa shuga. Metformin anathandiza. Mlingo waukulu, inde, koma pakadali pano wakhala akumwa kwa ine, ndipo shuga ndi wabwinobwino. Zachidziwikire, mtengo wake ukadakhala wotsika, koma palibe chifukwa chosankha. Zaumoyo ndizodula. Komabe, pamitengo yomwe ilipo mwina siyokwera mtengo, koma ndizovuta kwa okalamba. Koma okalamba onse, ali ndi ana, zidzukulu, amangokakamizidwa kuthandiza okondedwa awo ndi matendawa

Matenda a shuga masiku ano ndi ofala kwambiri ndipo zikuwoneka kuti pafupifupi munthu m'modzi pa atatu aliwonse amadwala matendawa.

Sindikudziwa ziwerengero, koma pazifukwa zina ndili ndi chitsimikizo kuti pafupifupi pabanja lililonse.

Wanga - pali awiri a iwo!

Awa ndi amayi anga ndi agogo anga.

Adakhala akudwala matendawa nthawi yayitali kuti amvetsetse zonse zokhudzana ndi izi, aphunzire kukhala nawo, komanso amayesetsa kukhalabe ndi moyo wosangalatsa komanso wabwino (momwe angathere), kudzilola okha ma pranks mwanjira yophwanya zakudya ndi zakudya.

Ine sindine dokotala, komabe ndiyesetsa kufotokoza zomwe abale anga anakumana nazo komanso mtundu wa "matenda ashuga" nyamayi, chifukwa madotolo adandifotokozera izi, ndipo chidziwitso changa chatsoka chimandilola kumvetsetsa izi.

Matenda a shuga a Mtundu Wachiwiri ndi kulekerera kwa shuga kwa insulin, ndipo kumva zamtendere kumabwera kale kwambiri kuposa anthu athanzi.

Ndiye kuti, insulini imapangidwa pamiyeso yambiri, osazindikira glucose m'magazi - osavuta.

China chilichonse, ngati mwadzidzidzi, mukuyenera kukumana ndi matenda afotokozere, kupereka ndi kupereka dokotala.

Banja lathu limatchedwa Metformin, limodzi ndi mankhwala ena.

Izi ndi zomwe mapiritsi a Metformin amawoneka.

Mapiritsi oyera ndi akulu, koma ndi osalala ndipo izi zimawathandiza kuti amizidwe mopweteka kwambiri)

Mlingo wovomerezeka ndi adokotala - 850 mg piritsi limodzi m'mawa ndi madzulo, pakudya kapena mutangomaliza kudya.

Zolemba malire - 3000 mg

Ndipo, inde, zakudya izi kwa moyo wake wonse, zomwe zingathandize kuti shuga azikhala m'malo ovomerezeka ndipo, ngati zingatheke, pewani zovuta zamtundu wa matenda ambiri amabadwa ndi matenda ashuga komanso kunenepa kwambiri.

Zachidziwikire, pali zotsutsana zambiri, ndipo sindiziwalemba apa - zidziwitsozi zikuwongolera, ndipo dokotala adzadziwadi ndikupanga chisankho), koma zabwino zomwe chithandizo cha Metformin zimabweretsa sizingafanane ndi malingaliro anga, mwina kwa abale anga .

Palibe zoyipa zomwe zidanenedwapo. Mankhwalawa amachita modekha koma moyenera.

Chofunikira kwambiri ndikukhazikika kwamasamba a shuga, kuponderezedwa kwa ludzu ndi njala, ndipo, motero, kusungirako zolemetsa m'njira yovomerezeka kapena yosavomerezeka.

Mankhwalawa amapezeka m'mafakisi. Ku Ukraine, operekedwa popanda mankhwala a dokotala.

Wopanga akhoza kukhala wosiyana, chifukwa izi sizimasintha.

Pali ma fanizo ena ambiri omwe chinthu chogwira ntchito ndi metformin komanso chomwe chingatengedwe. M'malo mwathu, iyi ndi Diaformin.

Chithandizo chachikulu. Ine ndimalimbikitsa.

Moyenerera komanso mochulukirapo kapena wotsika mtengo.

Koma mulimonsemo, lingaliro limakhalabe ndi dokotala - yekha, popanda mankhwala, mankhwalawa "Metformin" sanatenge.