Ikuwunika bwino kwa mmodzi wa atsogoleri ogulitsa m'mafakisi aku Russia

Chochititsa chidacho, chifukwa chomangidwa ndi dotolo, kuwopsa kwa matenda am ng'ombe komanso chitsimikizo cha opanga kuti mayesero azachipatala nthawi zambiri safunika. Zonsezi zikugwiranso ntchito pa mankhwala ena, omwe ali pakati pa atsogoleri ogulitsa ku Russia - Actovegin. M'ndime yake "Zomwe amatichitira", Indicator.Ru amamvetsetsa ngati mankhwalawa amagwira ntchito ndipo akufotokozera chifukwa chake aletsedwa ku USA ndi Canada.

Kuwunikira kwa kugulitsa kwa mankhwala a mankhwala kumawonetsa kuti nthawi yozizira kwambiri pachaka, choyambirira chimakhala cha mankhwala a fuluwenza ndi matenda ena owopsa a kupuma, monga Ingavirin, omwe takambirana m'nkhani yapita ya rubric. M'mwezi wa Marichi ndi Epulo, malinga ndi DSM Gulu, mankhwala osiyana ndi ena onse, Actovegin, omwe amapanga 0.76-0.77% yogulitsa kwathunthu m'miyezi iyi, amabwera pamzere woyamba.

Mankhwalawa amapatsidwa mankhwala ochizira a mtima komanso a metabolic a ubongo, kusokonezeka kwa magazi ndi zotsatira zake (zilonda zam'mimba), kupsa ndi mabala, zovuta za khansa komanso vuto la kukula kwa fetal mwa amayi apakati. Amapangidwa ndi kampani ya Sotex, yomwe ili ndi kampani ya Protek, yomwe, ndi ya Takeda Pharmaceutical, imodzi mwa makampani akuluakulu 15 azachipatala padziko lapansi. Pa tsamba lolembetsera boma zamankhwala, mankhwalawa amaperekedwa m'njira zambiri: mafuta opaka, ma gels, njira zothetsera jakisoni ndi kulowetsedwa, komanso ngakhale granules (mu gawo "la mankhwala opangira mankhwala").

Zambiri: zabodza kapena chipulumutso?

Actovegin adatulukira ngati generic (mankhwala omwe amagulitsidwa pansi pa dzina la mtundu womwe umasiyana ndi dzina loyambirira lomwe lili ndi kampani yopanga mapulogalamu - approx. Indicator.Ru) mankhwala ena - Solcoseryl, opangidwa kuyambira 1996 ndi Swiss kampani Solco. Patenti yamankhwala iliyonse imatha pakapita nthawi, ndipo kampani ina ikhoza kuyamba kuigulitsa pansi pa dzina lake, ndipo ingakhale yotsika mtengo kuigulitsa, chifukwa mtunduwo suyenera kuchitika. Ma generator otsika mtengo komanso otsika mtengo akukhala chipulumutso chenicheni cha maiko achitatu apadziko lonse lapansi, kotero kupanga kwawo kumathandizidwa ndi World Health Organisation.

Zoyipa zamagetsi ndizosowa kwa mayesero azachipatala (mosiyana ndi mawonekedwe omwe adadziwika), kusiyana kotheka mumlingo wogwira ntchito ndi zina zotulutsa, poyerekeza ndi mankhwala oyamba, chifukwa chotsatira chomwe chingachitike. Ndi zolephera zonsezi, mtengo wamankhwala ungasiyane kwambiri, ndipo ngakhale akatswiri a WHO azindikira kuti kusintha kotereku ndikwabwino kuposa kanthu.

Mankhwala oyambirirawa a Solcoseryl adagweranso mawunikidwe awiri apamwamba a Library ku Cochrane Library, yomwe imapereka umboni wothandizika kwa matekinoloje azachipatala ndi mankhwala. Chimodzi mwazinthuzi chimagwira ntchito yothandizira zilonda zam'munsi zam'magazi mwa anthu odwala cell magazi m'thupi pogwiritsa ntchito mitundu isanu ndi umodzi ya othandizira omwe amagwiritsidwa ntchito kunja (kuvala mabala, mafuta amkati) ndi mkati, kuphatikiza pamitsempha. Kuphatikiza pa Solcoseryl, mndandanda wamankhwala omwe anaphunziridwa amaphatikiza vitamini-ngati L-carnitine, isoxuprin, arginine butyrate, ma peptides a RGD ndi maantiotiranti wamba. Ndemangayi idazindikira kuyenera kwa zida zonse zomwe zidalembedwera zochizira zilonda zam'miyendo zam'mimba zodwala chifukwa cha kukula kwachitsanzo komanso kuthekera kwake.

Kuwunika kwina kumakhudza mavuto a kukula kwa fetal nthawi yomwe ali ndi pakati. Olembawo akuti pali "umboni wocheperako" womwe Solcoseryl, galactose, glucose, kapena carnitine wowononga amayi apakati amathandizira kuthetsa vutoli mwanjira iliyonse. Yankho la funso loti kope lingakhale labwino kuposa loyambirira, zingaoneke, ndilosiyana. Pakadali pano, wina akhoza kusiya kuwerenga mopitilira, koma sitikhala okondera. Kodi bwanji ngati zosayera komanso kusiyana kwa Solcoseryl zimapangitsa kuti ikhale yothandiza kwambiri?

Kuchokera kwa chiyani, kuchokera ku chiyani?

Gawo lomwe limagwiritsa ntchito mankhwalawo limatulutsidwa hemodialysate ya magazi a ng'ombe, ndiye kuti, mapuloteni osowa magazi ndi zina zazikulu, zopitilira 5 kilodalton. Malinga ndi malangizo, kusakanikirana kwa zinthu kumeneku kumasintha kapangidwe ka ATP (adenosine triphosphoric acid - chinthu chomwe selo imasungira mphamvu) mu "mphamvu zam'mimba", mitochondria, ndikuthandizira kugwiritsa ntchito mpweya ndi maselo. Ndi zinthu ziti zomwe zimaphatikizika motere zimayambira pamawu, koma zimaganiziridwa kuti izi ndi inositol phosphooligosaccharides.

Magawo opanga Actovegin amafotokozedwa pa Getactovegin.com (ngakhale ndi opanga mankhwala kapena ogulitsa, sizikudziwikiratu zomwe zingachitike), pomwe akuti) kuti kuyeretsa kambiri ndi zosefera kumapangitsa kuti mankhwalawa akhale otetezeka komanso osabala. Nkhani yomweyi, ikumalemba mapepala angapo asayansi, imatsimikizira kuti mankhwalawo ndi othandizadi komanso kuti imatha kuchita ngati insulin. Komabe, zonena zambiri zimayambitsa maphunziro a ntchito ya mankhwalawa malinga ndi maselo olumikizika a minyewa: mafuta (adipocytes) kapena "fibrous" (fibroblasts) makoswe kapena mbewa. Kuyeza kumeneku ndikofunikira kwambiri, koma madokotala sangathe kumangolekerera.

Tikuwona tsamba la Takeda Pharmaceutical m'Chingerezi, sitipeza chilichonse cha Actovegin mndandanda wa mankhwala omwe amagulitsidwa ndi kampaniyi. Pa tsamba lolankhula ku Russia la kampani ya Takeda Russia - CIS, ili pamndandanda wa mankhwala omwe amagulitsidwa ndi mankhwala. Komabe, kulumikizana ndi tsamba la mankhwalawo palokha actovegin.ru kumatipangitsanso ku tsamba la portal http://nevrologia.info, ndikulemba kudzera pailembo k kumabweretsa kutsamba lomwe mwini wake "adasankha kubisa malongosoledwe atsamba" (http://www.aktovegin.ru). Tiyeni tiwone zomwe zolemba za asayansi kuchokera kwa akulu ophatikizira mabuku asayansi amatiuza.

Pamndandanda (osati) olemba

Pali maphunziro ambiri okhudza kutha kwa Actovegin: kufufuza pamaziko a sayansi asayansi PubMed imapereka zochuluka monga nkhani za 133, zofalitsidwa kuyambira 1977 mpaka 2016. Pakati pawo 19 - ndemanga. Kubwereza kwa British Journal of Sports Medicine (zotsatira za 6.724) kumatsimikizira kuti umboni wochepa chabe wapezeka wokhudzana ndi kubayidwa kwa jekeseni wa Actovegin polimbana ndi kuvulala kwa hamstring.

Ndemanga kuchokera ku magazini yotchedwa Diabetes Obesity & Metabolism (zotsatira za 6.198), kuwunika momwe mankhwala osiyanasiyana amathandizira odwala matenda ashuga (vuto lamanjenje chifukwa cha kuwonongeka kwa mitsempha yaying'ono ndikutsitsa magazi ku mitsempha ya mitsempha), akumaliza kuti mankhwalawa akuphatikizidwa mu lachitatu ( gawo lomaliza) la mayeso azachipatala, palibe, kuphatikiza Actovegin, adavomerezedwa ndi FDA (Food and Drug Administration, Food and Drug Administration) ndi European Medical Commission chifukwa cha zovuta zokayikitsa ivnosti.

Pafupifupi, maphunziro ambiri amasindikizidwa mu Germany, kapena Chirasha, kapena m'magazini ena ang'onoang'ono amitundu. Mwachitsanzo, nkhani ina yonena kuti kutenga Actovegin amathandizira posowa oxygen m'mwana wosabadwa ngakhale inatuluka mu Georgia News News. Anatuluka mu 2006, nthawi imeneyo zomwe zimapangitsa magaziniyo kukhala 0,07. Zitsanzozo zinali zochepa kwambiri, ndipo mwa azimayi 36, kuyambitsidwa kwa Actovegin, glucose ndi vitamini C adathandizira 24 okha.

Kafukufuku wina wofotokozera momwe mankhwalawa amathandizira odwala omwe ali ndi matenda ashuga, omwe adafalitsidwa mu Chirasha mu magazini ya atlepu ya Acapin, adapangidwa pa anthu 500 - odwala a Vidnovsky District Clinical Hospital. Ntchitoyi ikuwonetsa kuti gululi lomwe likugwiritsa ntchito Actovegin linali ndi edema mwachangu komanso kutentha kwa malo omwe anakhudzidwa kunachepa. Komabe, pankhani iyi, madotolo sanagwiritse ntchito njira yawiri yakhungu, pomwe wodwalayo ndi wasayansi sakudziwa yemwe alandila mankhwalawo ndipo ndi ndani amene ali placebo mpaka kumapeto kwa mayeso.

Zikakhala choncho, dokotalayo amatha kupereka mankhwala mwachidziwitso kapena mwadala kwa anthu omwe ali ndi vuto labwino kwambiri, zomwe zingasinthe zotsatira zake (onani m'mabuku kuti mapangidwe a magaziniyo ndi 0.142). Gawo la kafukufukuyu, mwina zaka zapitazi (zidachitika kuyambira kumapeto kwa zaka za m'ma 1990 mpaka 1990), kapena pazifukwa zina, ndizovuta kupeza zonse, ngakhale zimatchulidwa kawiri kawiri ndipo njira yolamulidwa ndi khungu yakumbuyo imatchulidwa m'mazina awo (mwachitsanzo, onani kafukufukuyu).

Pakadali pano, Takeda Pharmaceutical ikuchita kafukufuku wambiri, wosaona, komanso wowongolera m'malo mwa Actovegin, pomwe zitsanzo za odwala 500 atakumana ndi vuto la mtima (kuchokera ku zipatala ku Russia, Belarus, Kazakhstan) akulemba, koma pakadali pano lingaliro ndi kapangidwe kake zidasindikizidwa.

Maphunziro a Actovegin alipo pa mndandanda wa mayesero azachipatala a Cochrane, koma pali ndemanga imodzi yokha. Malinga ndi kuwunika kumeneku, kutengera deta kuchokera ku mayeso asanu ndi anayi azachipatala, omwe amavala odwala okwana 697, omwe ali ndi kutupa kwa zotupa za Achilles, Actovegin amawaganizidwanso, limodzi ndi njira zina zamankhwala. Olemba ndemangawa akuti mankhwalawa ndi "olimbikitsa," koma kuwonongeka kwa omwe adawathandizawo kuli kotsutsana, ndipo zitsanzozo ndizochepa. Koma kufupi ndi kubwereza kumeneku, komwe kudasindikizidwa mu 2001, kudalembedwa ANDDRAWN ("anakumbukiridwa") mu 2011. Kodi chingakhale chifukwa chani pa chisankhochi?

Kulephera, Ndende komanso Matenda a Mad Cow

Mu 2000, Actovegin anali pachiwopsezo cha masewera. Otenga nawo mbali mu mpikisano wapaulendo wa pa njinga ya Tour de France, kuphatikiza Lance Armstrong, wopambana wake wa zisanu ndi ziwiri (USADA v. Armstrong, Chisankho cholingalira, gawo IV B 3.e (pp. 42-45) (USADA 10), akuwopsezedwa kuti amagwiritsa ntchito limodzi ndi mankhwala ena osokoneza bongo Ogasiti 2012)). Ngakhale kuti ndizovuta kudziwa za mankhwalawa m'magazi (magazi athu omwe ali ndi zinthu zomwezo), mapaketi osindikizidwa a mankhwala omwe amapezeka ndi omwe anali chifukwa chomuimbira mlandu. Komabe, monga momwe kafukufuku wina wasonyezera (ngakhale sanasindikizidwe mu utoto wapamwamba kwambiri wa International Journal of Sports Medicine), mankhwalawa sathandiza othamanga kusintha magwiridwe awo.

Koma kugwiritsidwa ntchito kwa mankhwala okayikitsa ndi akatswiri othamanga sikunathe pompo. Nkhani yotchedwa anaphylactic shock in a cyclist itayesedwa poyesa kuchitira kuvulala kwake ndi Actovegin, koma pambuyo pake zidapezeka kuti mankhwalawo amayenera kuti anali ambiri, ndiko kuti, chifukwa cha poyizoni wamagazi, omwe mwina sanagwirizane ndi mankhwalawa.

Mu Julayi 2011, tsamba la FDA lidalengeza chigamulo cha nzika yaku Toronto wazaka 51 wotchedwa Anthony Galea, yemwe adagwirapo ntchito ndi osewera (nthawi ino, mpira ndi basketball) ndipo adalemba mankhwala osaloledwa: Actovegin ndi mahomoni akukulitsa anthu. Mwa zina, adotolo adagwira ntchito popanda chilolezo chapadera kuchokera kwa akatswiri azachipatala. Pa izi, adaweruzidwa kuti akhale m'ndende zaka zitatu, ndalama zokwana 250,000 dollars ndi kulanda katundu mu ndalama 275,000 dollars.

Kutulutsa komweku kumawonetsa kuti mankhwalawa "samavomerezeka kuti aliyense agwiritse ntchito." Chomwe chimaletsa izi ndi chiwopsezo chachikulu chotenga kachilombo ka matenda a prion omwe amakhudza amanjenje amanjenje. Ng'ombe, iyi ndi spongiform encephalopathy (ndiyonso matenda amisala), ndipo mtundu wa anthu umatchedwa matenda a Creutzfeldt-Jakob. Zomwe zimayambitsa matenda a prion ndi mapuloteni osakhazikika bwino, omwe "amapatsira" mapuloteni ena ndi mawonekedwe ake, omwe amatsogolera kuwonongeka kwa minyewa yamanjenje. Imfa yovulala kwambiri imakhala pafupifupi 85%, pomwe kufa koopsa sikumatha konse.

Kuphulika kwa mtundu watsopanowu kudalembedwa posachedwa, mu 2009. Pofuna kuteteza anthu ku matenda atsopano, chiletso chinakhazikitsidwa pakupanga, kutumiza ndi kupereka mankhwala omwe ali ndi magawo azomwe zimayambira nyama ku USA ndi Canada kudzera momwe mapuloteni a prion amatha kupatsirana. Kukula kwa mahomoni omwe amachokera ku pituitary gland ndi zinthu zokhudzana ndi seramu yazinyama amakhalanso pamndandandawu.

Komabe, izi komanso zomwe nthawi zina zimaneneza kuti zachitika popanda kuwonetsa umboni wosatsutsika wothandizika sizivutitsa omwe amagwiritsa ntchito mankhwala m'maiko a CIS.

"Ku Russia, kuyeserera kwa mankhwalawa sikofunikira kwenikweni, chifukwa chake kusakhala vuto kwa ife," Purezidenti wa Nycomed ku Russia Josten Davidsen adanena pokambirana ndi Kommersant pomanga mafakampani atsopano m'dera la Yaroslavl. "Chifukwa chiyani sitichita?" Chifukwa sitimva kufunika kochita izi. Tikuwona kuti mankhwalawa akufuna ndi madokotala aku Russia, amalimbikitsa kwa odwala. Imeneyi ndi mfundo yofunika, chifukwa madokotala ku Russia ndiwosakhazikika ndipo amatsatira njira zodziwika bwino komanso zamankhwala zodziwika bwino. Nawonso ogula amakhala okhulupirika ku Actovegin. Kuphatikiza apo, masiku ano kulibe mankhwala ogwiritsanso ntchito masiku ano. ”

Chizindikiro.Ru Kuyikira: samalani

Fotokozerani mwachidule zonse zomwe tapeza. Ngati mankhwalawa amadziwika kuti ndi osakhazikika, ndiye kuti generic alibe mwayi wotsimikiza. Opanga amakhulupirira kuti chinthu chachikulu ndikupezeka kwa zofuna, ndipo iwonso amavomereza kuti sikofunikira kuyesa mankhwalawa molingana ndi mitundu yonse ya mankhwala omwe ali ndi umboni usanayambe kugulitsa. Zabwino kwambiri komanso kukwaniritsa njira zake sizinafikebe, koma mapulani ake ndi omwe amafalitsidwa. Webusayiti ya chilankhulo cha Chingereziyi idabisira kutchulidwa konse kwa Actovegin, mwina chifukwa chakuti mankhwalawo aletsedwa ku Canada ndi United States, zomwe zikutanthauza kuti opanga sawadaliranso omvera awa. Mankhwala okhala ndi zofunikira za nyama amaletsedwa m'maiko ambiri chifukwa choopsa cha kufalikira kwa matenda a prion.

Lamulo la Unduna wa Zaumoyo wa Russia Federation Nambala 15 “Pa njira zoletsa kufalikira kwa matenda a Creutzfeldt-Jakob ku Russian Federation” pa Disembala 15, 2000 kuyambitsa kuletsa kulowetsedwa ku Russia kwa "nyama, nyama ndi zinthu zina zopha ng'ombe ku UK, Portugal, Switzerland, ndizochepa. Kugulitsa zinthuzi kuchokera kumadipatimenti asanu ndi anayi a France ndi zigawo zisanu ndi chimodzi za Republic of Ireland. ” Ndikulimbikitsanso kukana kutumiza mankhwala omwe amapangidwa kuchokera ku chiwalo chaumunthu m'maderawa. Komabe, mosiyana ndi zikalata zofananira zomwe zakhazikitsidwa ku Republic of Belarus ndi Ukraine, sizikuphatikiza mndandanda wazomwe mankhwalawo ali ndi zanyama pazomwe zimapangidwa, chifukwa chake, tsopano, kutumiza kwa Actovegin, komwe kumapangidwa ku Switzerland, ku Russia ndikuloledwa.

Mayiko a Eastern Europe ndi CIS sanagwere m'gulu lachiwopsezo, zomwe zikutanthauza kuti ndizotheka kupanga mankhwala okhala ndi zoopsa pazigawo zawo. Koma chikalata chomwechi chikuwonetsa kuti m'maiko ano, akatswiri a WHO sakhala ndi chidziwitso chodalirika, chifukwa chake sitikudziwa momwe kufalikira kwa kachiromboka kungathere.

Chifukwa chake, udindo wa chisankho ichi komanso thanzi lawo liri kwathunthu ndi wogula. Mwina mankhwalawa amagwiradi ntchito, ndipo zotsatira zoyesa zingapo zabwino m'magazini ang'onoang'ono asayansi ndizowona, ndipo kafukufuku wokhazikitsidwa kwakukulu amangowatsimikizira. Komabe, izi sizitanthauza kuti kufalikira kwa matenda a prion, chifukwa chake ndi bwino kukana chithandizo chotere, pokhapokha njira yowunikira chitetezo yotereyi ikugwira ntchito m'mafakitale aku Russia.

Malangizo athu sangafanane ndikusankhidwa kwa dokotala. Musanayambe kumwa izi kapena mankhwalawa, onetsetsani kuti mwakumana ndi katswiri.

Zizindikiro zogwiritsidwa ntchito

Actovegin amapangidwa pamaziko a kunyongedwa kwa hemoderivative ku magazi a ng'ombe. Monga tawonera kale, zimapangitsa kagayidwe kachakudya pama cellular cell, kamene kamatsimikizira kuti mpweya wabwino umapezeka kuzinthu zowoneka bwino komanso kumathandizira magazi. Patsamba lamayikidwe a mankhwala mumatha kuwona mafuta, mafuta, mapiritsi ndi jakisoni.

Chipangizocho chikuyenera kuperekedwa ndi adokotala okha. Tsitsi ndi mafuta, amathandiza ndi zotupa pakhungu, zilonda zamkati ndi zopsinjika.

Malangizo ogwiritsira ntchito akuwonetsa kuti mapiritsi a Actovegin ndi omwe amaperekedwa chifukwa cha matenda monga:

sitiroko
kusokonezeka kwa magazi muubongo,
TBI,
dementia
matenda ashuga polyneuropathy,
kuvulala kwamitsempha
ulcerative process of trophic chikhalidwe,
angiopathy.

Pogwiritsa ntchito jakisoni a Actovegin, zikuwonetsa zomwezo. Kusankhidwa kwa mawonekedwe a kumasulidwa kwa mankhwalawa kudzatengera kuopsa kwa matenda.

Malangizo omwera mankhwalawa

Jakisoni amagwiritsidwa ntchito jakisoni wamkati ndi mu mnofu, amathanso kukhala dontho.

Pa magawo oyamba a mankhwala othandizira, mlingo umakhala wokwera, pakapita nthawi umakhala wocheperako. Pakutha kwa chithandizo, amaloledwa kulowetsa jakisoni wa Actovegin ndi mapiritsi. Mwambiri, nthawi yayitali imakhala masiku 30-45.

Ponena za piritsi la mankhwalawa, ayenera kumwedwa. Madokotala nthawi zambiri amalimbikitsa kuti odwala awo amwe mapiritsi atatu katatu patsiku. Pambuyo pothandizidwa ndi chithandizo, mlingo wa tsiku ndi tsiku umachepetsedwa.

Muubwana, mankhwalawa amatha kumwa ngati mwana wafika zaka zitatu, mlingo wa tsiku ndi tsiku ndi piritsi limodzi.

Contraindication ndi zoyipa zimachitika

Monga mankhwala aliwonse Actovegin ali ndi ma contraindication angapo, amaphatikiza

oligouria,
pulmonary edema,
Anuria
kulephera kwa mtima
tsankho
mimba mu trimester yoyamba.

Zotsatira zake zoyipa, kugwiritsa ntchito mankhwalawa kungayambitse:

thupi lawo siligwirizana mu urticaria,
hyperhidrosis
kuchuluka kwa kutentha kwa thupi,
maonekedwe a kuyabwa
lacure
Hyperemia wa sclera.

Zomwe ziyenera kukonda - majakisoni kapena mapiritsi?

Palibe yankho lomaliza ku funso loti kusiyana pakati pa jakisoni ndi mapiritsi a Actovegin ndi zomwe ndi bwino kugwiritsa ntchito, ndi izi kapena chikhalidwe cha pathological. Chilichonse chimadalira mtundu wamatenda, kuuma kwa njira yake, zaka zake komanso zomwe wodwalayo ali nazo.

Timapereka chitsanzo, pakakhala zovuta zamanjenje, njira yoyenera yodzithandizira ingakhale mtundu wa mankhwalawa, chifukwa amatha kuunjikira patsekeke la thupi. Ngati wodwala akudwala matenda ashuga, ndibwino kuperekera jakisoni, chifukwa mwanjira imeneyi chinthu chogwira thupi chimalowa mkatikati thupi ndikufalikira kudzera mwa iye.

Ngati ndi kotheka, Actovegin akhoza m'malo ndi analogues:

Cortexin,
Vero-Trimetazidine,
Cerebrolysin
Curantil-25,
Solcoseryl.

Ponena za zakumwa zambiri, ziyenera kukumbukiridwa kuti chinthu chofanana chogwira ntchito chimapezeka mu Solkseril chokha. Mtengo wake udzadalira dziko lomwe amapanga mankhwalawo.

Vidal: https://www.vidal.ru/d drug/actovegin__35582
Radar: https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGu>

Mwapeza cholakwika? Sankhani ndikusindikiza Ctrl + Lowani

Mbiri yanu

Zomwe zili mu yankho la Actovegin ndizachilengedwe, motero sikungatheke kuti aphunzire ma pharmacokinetics atamwa. Mankhwalawa amapereka mphamvu zake mwakuwonjezera mphamvu kagayidwe. Imathandizira kugwiritsa ntchito mpweya ndipo izi zimawonjezera kukana kwa njala yakufa m'matumbo a thupi.

Monga tafotokozera kale, pogwiritsa ntchito njira za pharmacokinetic, ndizosatheka kuphunzira za mankhwala a pharmacokinetic (mayamwidwe, kugawa, kuchotsetsa) pazomwe zimagwiritsidwa ntchito ndi mankhwala Actovegin, popeza zimangokhala ndi ziwalo zolimbitsa thupi zomwe nthawi zambiri zimapezeka m'thupi.

Mpaka pano, palibe chifukwa choganiza kuchepa kwa mankhwalawa chifukwa cha odwala omwe ali ndi vuto la kuwonongeka kwa thupi ndi chimbudzi cha zinthu zowola.

Kugwiritsa ntchito mankhwala ofotokoza umboni, zimadziwika kuti Actovegin momwe amapangira jakisoni imalowa mwachangu kuzungulira dongosolo ndipo chinthu chogwira chimagawidwa m'thupi lonse, chomwe chimapangitsa kuti izi zitheke mwachangu.

Mankhwala ofotokoza umboni

Panali zolemba zambiri pa intaneti yapadziko lonse pamutuwu kuti palibe umboni wowonetsa bwino momwe majakisoni a Actovegin chifukwa chake ndizopanda ntchito. Umboni wonse wazokhudza izi umachokera pazinthu zonse zomwe zimapangitsa madokotala ambiri.

Koma, pali nthambi ngati yamankhwala ngati mankhwala othandiza kupeza umboni, yomwe pochita kwakanthawi kochepa imatsimikizira kuyenera kwa mankhwala ena ake.

Izi zidachitika ndi Actovegin, yomwe yakhala yogulitsa mankhwala kwa zaka zoposa 30 ndipo ndemanga zake zili zabwino kwambiri kuchokera kwa odwala komanso akatswiri otsogolera, zomwe zikutanthauza kuti palibe chifukwa choganizira kuti mankhwala a nootropic alibe ntchito.

Zizindikiro ndi contraindication kuti mugwiritse ntchito

Zisonyezero zogwiritsa ntchito Actovegin mu mawonekedwe a jakisoni:

zovuta za neuralgic (kuphatikiza ischemic stroke, hypoxia, kuvulala kwamtundu wamatumbo),
matenda ashuga
kuphwanya magazi ndi kagayidwe,
mitsempha ya varicose,
kuyanʻanila kamvekedwe ka mtima.

Mankhwalawa amathandizidwanso kuti achiritse mofulumira mabala komanso kuwotcha mosiyanasiyana.

Actovegin mu ampoules alibe contraindication pamagwiritsidwe ake, koma osavomerezeka kuti apatsidwe jakisoni ngati wodwala ali ndi vuto lililonse mwazigawo zina za mankhwalawa.

Malangizo ogwiritsira ntchito

Ntchito jakisoni wa Actovegin kudzera m'mitsempha kapena intramuscularly (kutengera mtundu ndi matenda). At kulowetsedwa kwa mtsempha, mankhwalawa amalembedwa mu mawonekedwe a dontho kapena mtsinje, ndipo asanayende, mankhwalawa amasungunuka mu yankho la sodium kolorayidi kuti kuthetsedwe mwachangu mukalowa thupi. Poterepa, mlingo wa tsiku ndi tsiku suyenera kupitirira 20 milligrams.

Ponena za makonzedwe a mu mnofu, pamenepa, choyamba, ndikofunikira kusankha mlingo wofunikira. Poyamba, amapanga mamiligalamu 5 mpaka 10 pa kugogoda ndipo, ngati kuli kofunikira, amawonjezeka ndi mamiligalamu asanu sabata iliyonse. Jakisoni amaperekedwa kudzera m'mitsempha popanda mankhwala ena ndi sodium mankhwala ena.

Mankhwala oterewa a nootropic nthawi zambiri amagwiritsidwa ntchito pochiza zovuta, kuphatikiza pochiza matenda a neuralgic.

Mankhwala osokoneza bongo ambiri komanso zoyipa

Mwamwayi, ngati mlingo woyeserera wa mankhwalawo udapitilira, ndiye kuti cholakwika chotere sichikuwopseza wodwalayo, chifukwa ndizosatheka kuvulaza thupi ndi zofunikira zathupi zomwe zimapezeka ku Actovegin.

Monga momwe machitidwe amasonyezera, mankhwalawa amalandiridwa bwino ndi odwala ndipo samayambitsa mavuto. Komabe, nthawi zina, anaphylactic komanso thupi lawo siligwirizana chifukwa cha tsankho la mankhwalawa limatha kuchitika. Kuphatikiza apo, zotsatirazi zoyipa nthawi zina zimachitika mukamamwa Actovegin:

kufiira pakhungu kapena kuzimiririka thupi
general malaise
nseru ndi kugwedezeka
kupweteka mutu komanso kusazindikira,
kuphwanya kwam'mimba,
kupweteka kwa molumikizana
kupuma movutikira, ndipo nthawi zina kumatsamwitsidwa chifukwa cha kuwuma mumayendedwe ammlengalenga,
thukuta kwambiri
Kusayenda kwamadzi mthupi,
chifukwa cha kuuma kwa mpweya, wodwalayo atha kukhala ndi vuto la kumeza madzi, chakudya ndi malovu,
boma losangalala ndi zochitika.

Malangizo apadera ogwiritsa ntchito

Wopanga sanapereke chidziwitso pakuwonjezera malangizo okhudzana ndi kumwa mankhwalawo. Koma, odwala ambiri amadziwa kuti ndi matenda ashuga, wodwalayo amayenera kumwa mankhwalawa moyang'aniridwa ndi dokotala, pomwe amasunga madzi mthupi, omwe nawonso amavulaza thupi ndi matenda ashuga.

Kubwereza Kwa Doctor

Chochita chachikulu cha Actovegin ndikupititsa patsogolo kayendedwe ka okosijeni m'magazi oyendayenda. Chifukwa cha zofunikira zachilengedwe zomwe zimapanga mankhwalawa, kayendetsedwe ka kayendetsedwe kazake kamakongoletsa kagayidwe kazakudya ka m'maselo a minofu ya thupi la munthu chifukwa chogwiritsa ntchito, kudziunjikira, kusuntha ndikumasulidwa kwa mpweya ndi glucose.

Mankhwalawa amakonzanso magazi m'maselo a minyewa, amathandizira kubwezeretsa minofu yowonongeka, komanso amathandizira thupi kuyamwa zinthu zofunika komanso zinthu zina.

Lowani Actovegin wodwala angathe:

Intramuscularly - 5 ml patsiku, njira ya mankhwala - 20 jakisoni.
Mothandizidwa: jakisoni wa jet - 10 ml patsiku, kapena chikwangwani - amaikidwa mu 200 ml ya saline yokhudza thupi kapena 5% yankho. Mulingo wa oyang'anira sayenera kupitirira 2 ml pa mphindi.

Mlingo wa Actovegin wa kulowetsedwa kulowetsedwa zimatengera mawonekedwe amomwe amapangira matenda,

ischemic stroke sabata iliyonse, mpaka 50 ml / tsiku limayendetsedwa, ndiye mkati mwa milungu iwiri - mpaka 20 ml / tsiku,
matenda amisala - masabata awiri pa 10-20 ml / tsiku,
zovuta kuchiritsa kuwonongeka kwa khungu - 10-20 ml tsiku lililonse.

Malingaliro odwala

Ntchito yantchito kuntchito imadzipangitsa kumva, makamaka mukatsegula bizinesi yanu yaying'ono ndipo mukumangokhala mumapanikizika, komwe, komwe kumakhudza thanzi lanu.

Pambuyo pa masabata angapo amanjenje, ndidayamba kuwona kuwonongeka kwadzidzidzi, mantha ambiri ndikuwotcha nthiti. Sindinayimirire izi, chifukwa ndimaganiza kuti zimangotambasulidwa, koma tsiku lililonse zinkawonjezeka ndipo ndimapita kwa adotolo.

Anandipeza ndi neostgia neuralgia yokhudzana ndi kupsinjika. Monga chithandizo, adandiuza mankhwalawa a nootropic Actovegin mu mawonekedwe a jakisoni, ndipo mkati mwa sabata limodzi ndimamva bwino.

Nikita Milev, wazaka 30

Kuyambira ndili mwana, vuto langa lalikulu ndi kusatetezeka kwa chitetezo cha mthupi, zomwe nthawi zambiri zinkakhudza thanzi langa ndipo ndinali mwana wodwala. Ndili ndi zaka 19, ndidadwala matenda a herpetic neuralgia - matenda omwe amakhudza malo ozungulira maso.

Nthawi yomweyo ndidapita kwa adotolo, ndipo adandiuza kuti ndidye za Actovegin ndipo patatha milungu iwiri matendawa adayamba kupunthwa, ndipo patatha mwezi umodzi ndidazichotsa. Mwa njira, mankhwalawa amathandizanso chitetezo chokwanira.

Anastasia Shpanina, wazaka 20

Malangizo Odwala

Zofunikira za Actovegin yankho la mankhwala zimatha kuyambitsa mavuto ambiri mwa munthu. Odwala ambiri amalimbikitsa kuti, ngati zizindikiro za ziwopsezo zimawonekera, siyani mankhwalawo ndi mankhwalawo, kuti muchepetse vutoli.

Monga lamulo, pambuyo pa kukwiya kwa thupi lonse kwadutsa, dokotala yemwe amapezekapo amasankha yankho latsopano momwe mulibe mitundu yonse ya ziwengo.

Ubwino ndi kuwonongeka kwa zinachitikira

Mwa zabwino zotchulidwa za mankhwalawa, zotsatirazi ziyenera kusiyanitsidwa:

ntchito yabwino
zoyipa zochepa
mankhwalawa matenda a neuralgic, njira yachipatala imakhala ndi mphamvu yogwira ntchito komanso
ntchito zosiyanasiyana.

Pali zotsutsana, kuphatikizapo thupi lawo siligwirizana.

Kapangidwe ka Actovegin m'mapiritsi ndi jakisoni

Maziko a mankhwalawa Actovegin ndi wochotsa magazi a ng'ombe, omwe ali ndi mphamvu ya kagayidwe kachakudya.

Zomwe zili mu mayankho a jakisoni zimatengera kuchuluka kwa zochuluka:

80 mg yokhazikika mu ampoules omwe ali ndi 2 ml yankho,
200 mg yogwiritsa ntchito - 5 ml ampoules,
400 mg - mu ampoules a 10 ml.

Monga chinthu chothandizira, madzi a jakisoni amagwiritsidwa ntchito.

Zomwe zimagwira pa fomu ya piritsi ndi Actovegin granate, i.e. kuchotsedwera kuchotsera magazi a ng ombe, ophatikizidwa ndi ma cellcose a microcrystalline ndi povidone K-90. Kuphatikiza apo, phalelo lidzakhala ndi talc ndi magnesium stearate ngati zosakaniza zothandizira.

Njira yothetsera vutoli kudzera mu intramuscular, intravenous kapena drip management imathamanga ndipo imalowa mokwanira m'magazi.

Zophimba zoteteza mapiritsi kuti asinthe katundu wawo ndikupangitsa makonzedwe kukhala ndi glycol wax, diethyl phthalate, talc, titanium dioxide, sucrose, acacia chingamu, povidone K-30, hypromellose phthalate, macrogol ndi utoto wachikasu.

Kusiyana mitundu yamankhwala

Zizindikiro za kutenga Actovegin m'mapiritsi kapena mwanjira yothetsera, malinga ndi malangizo ogwiritsira ntchito, pafupifupi zofanana. Kusiyana kwakukulu pakati pa mitundu ya mankhwalawa ndikuti yankho, mukamapaka intramuscularly, kudzera m'mitsempha kapena magazi, amalowa m'magazi mwachangu komanso mokwanira, kupatsa thupi mlingo waukulu wa chinthu chomwe chikugwira ntchito.

Mapiritsi amalowa m'mitsempha yamagazi pokhapokha amamwa matumbo, i.e. izi zisanadutse m'mimba. Izi zikutanthauza kuchedwa popereka mankhwala kwa magazi ndikuchotsa pang'ono mbali imodzi ndi machitidwe achilengedwe.