Desoxinate - Kufotokozera za mankhwala, malangizo, ntchito, ndemanga

Munkhaniyi, mutha kuwerengera malangizo ogwiritsira ntchito mankhwalawa Desoxinate. Amapereka ndemanga kuchokera kwa alendo omwe amabwera patsamba lino - ogula mankhwalawa, komanso malingaliro a akatswiri azachipatala pakugwiritsa ntchito Deoxinat machitidwe awo. Chopempha chachikulu ndikuti muwonjezere ndemanga zanu za mankhwalawa: mankhwalawo adathandizira kapena sanathandizire kuchotsa matendawa, ndizovuta ziti zomwe zimawoneka ndi zotsatirapo zake, zomwe mwina sizinalengezedwe ndi wopanga. Mndandanda wa Deoxinate pamaso pazojambula zopezeka. Gwiritsani ntchito mankhwalawa trophic zilonda, kuwotcha, matenda a radiation, leukopenia, kupewa kupatsidwa zina mwa akulu, ana, komanso pa nthawi ya bere. The zikuchokera mankhwala.

Desoxinate - Mankhwala omwe amachititsa kuti chitetezo cha cellular ndi chochititsa manyazi. Iwo ali achire zotsatira ulcerative necrotic zotupa za pakhungu ndi mucous zimagwira ntchito zosiyanasiyana kutulutsidwa. Kugwiritsa ntchito mankhwala Deoxinate mwanjira ya mavalidwe, ntchito ndi ma rinses kumathandizira, kumachepetsa kuwonetsa kwa zomwe zimachitika, kumapangitsa kukula kwa granulations ndi epithelium. Ndi njira zothandizira pamwambo wokonzanso, zimabweretsa kuchira mwachangu. Deoxinate amathandizira kukulitsa kuwunikira kwa magalimoto pamawonekedwe oyaka, komanso kulumikizana ndi opaleshoni ya pulasitiki ya zofooka m'dera la maxillofacial. Kugwiritsa ntchito Deoxinate sikumayendera limodzi ndi zoyipa komanso zamkati.

Kupanga

Sodium deoxyribonucleate + Excipients.

Pharmacokinetika

Ikagwiritsidwa ntchito timitu tambiri, dexinate imatengedwa ndikugawika ziwalo ndi minyewa ndikugwira nawo gawo la endolymphatic. Mu gawo la kumwa kwambiri magazi kulowa m'magazi, kugaŵananso kumachitika pakati pa madzi am'magazi ndi maselo amwazi, limodzi ndi kagayidwe kachakudya ndi zotupa. Desoxinate imapangidwa mu thupi kupita ku xanthine, hypoxanthine, beta-alanine, acetic, propionic ndi uric acid, omwe amachotseredwa ndi impso komanso pang'ono kudzera m'mimba.

Zizindikiro

  • matenda a radiation, kuphatikizapo dermatitis ya radiation, zilonda zam'maso zoyambilira ndi mochedwa, pachimake radiation pharyngeal syndrome,
  • kutentha kwamoto pakhungu madigiri awiri azitsukali,
  • Zilonda za trophic, kuphatikiza ndi mitsempha ya varicose yam'munsi,
  • kuphwanya umphumphu wa mucous nembanemba wamkamwa, mphuno, nyini, rectum,
  • Zilonda zakale za pakamwa komanso pakhungu,
  • mavuto omwe amachitika ndi cytostatic mankhwala (stomatitis, pharyngoesophagitis, gingivitis, uvulitis, enterocolitis, vulvovaginitis, paraproctitis, leukopenia),
  • kupewa kufalikira kuphatikizidwa pokonza matupi a auto- kapena allotransplantation komanso munthawi ya kufalikira,
  • kuchira nthawi pambuyo kwambiri matenda opatsirana komanso matenda ena.

Kutulutsa Mafomu

Yothetsera mu mnofu ndi subcutaneous makonzedwe a 0,5% mu ampoules 5 ml ndi 10 ml.

Yothetsera zakunja ndi zakunja kwa ntchito 0,25% mu 5 ml, 10 ml, 20 ml ndi 50 ml mbale.

Malangizo ogwiritsira ntchito ndi mtundu wa mankhwala

Mankhwalawa amalembera ana kuyambira tsiku loyamba la moyo ndi akulu.

Zochizira zilonda zapakhungu, kwezani mavalidwe ndi yankho, m'malo mwa 3-4 pa tsiku.

Potupa kwa zotupa za pakamwa, ziphuphu zimachitika ndi yankho la Deoxinate (kanayi pa tsiku, 5-15 ml, kenako ndikumeza).

Mu nyini, Deoxinate amatumizidwa pa swab, mu rectum mu enema (20-50 ml).

Kutalika kwa maphunzirowa kukupitirirabe kwa zizindikiro za kutupa kapena kutulutsa khungu ndi ma mucous (masiku 4 mpaka 10).

Intramuscularly (pang'onopang'ono) kapena pang'onopang'ono, Deoxinate imaperekedwa kwa akulu ndi ana kamodzi - 15 ml ya yankho la 0.5% (75 mg ya yogwira ntchito). Mobwerezabwereza makonzedwe munthawi yotsatira ya chemotherapy, radiation kapena chemoradiation chithandizo cha odwala khansa amaloledwa. Mankhwalawa pachimake radiation matenda - pasanathe maola 24 kuchokera kukhudzana.

Zotsatira zoyipa

  • hyperthermia yochepa (maola 2 - 2, maola 3 mpaka 3 kuchokera ku utsogoleri) kuchokera pa manambala ocheperako mpaka manambala achabechabe,
  • ndi makonzedwe amkati mwachangu - kupweteka kwapfupi pamalo a jekeseni, osafuna chithandizo,
  • kugwiritsa ntchito apakhungu sikumayambitsa mavuto.

Contraindication

  • Hypersensitivity kuti sodium deoxyribonucleate kapena chinthu chilichonse cha mankhwala.

Mimba komanso kuyamwa

Mankhwala amavomerezedwa kuti azigwiritsidwa ntchito panthawi yoyembekezera komanso mkaka wa m`mawere.

Gwiritsani ntchito ana

Gawani ana kuyambira tsiku loyamba la moyo.

Gwiritsani ntchito odwala okalamba

Odwala okalamba safuna kusintha kwa mlingo.

Malangizo apadera

Intravenous makonzedwe a yankho la Deoxinate saloledwa.

Mankhwalawa ndi osagwira ntchito zowononga kwambiri, zozama kwambiri za necrosis, zomwe zimadziwika kuti ndi gawo 4.

Kuyanjana kwa mankhwala osokoneza bongo

Deoxinate sigwirizana ndi mafuta okhala ndi mafuta komanso hydrogen peroxide.

Mndandanda wa mankhwala Deoxinate

Zofanana muzochitika zamagulu:

  • Derinat
  • Sodium deoxyribonucleate,
  • Panagen.

Mndandanda wa mankhwala Deoxinate malinga ndi gulu la mankhwalawa (obwezeretsanso komanso obwezeretsanso):

  • Adgelon
  • Actovegin,
  • Aloe yotulutsa madzi,
  • Alginatol,
  • Apilak
  • Balarpan
  • Mafuta a Shostakovsky,
  • Bepanten
  • Maluwa amchenga ammawa,
  • Beta carotene
  • Achimachik
  • Biartrin
  • Zachikhalidwe
  • Vinylinum
  • Vitanorm,
  • Hyposol N,
  • Gumizol,
  • D-Panthenol
  • Dalargin
  • Dexpanthenol,
  • Immeran
  • Intragel
  • Inflamistine
  • Cambiogenplasmid,
  • Korneregel,
  • Ximedon
  • Curiosin,
  • Masewera a Rhizome,
  • Balsamic liniment (malinga ndi Vishnevsky),
  • Methyluracil
  • Meturacol,
  • Moreal Plus,
  • Sodium deoxyribonucleate,
  • Mafuta amafuta am'nyanja,
  • Zachinyengo
  • Panagen
  • Panthenol
  • Pantoderm
  • Pentoxyl
  • Mafuta oyenga
  • Dzimira madzi,
  • Polyvinylinine
  • Polyvinox
  • Prostopin
  • Retinalamine,
  • Rumalon
  • Sinoart
  • Solcoseryl,
  • Stellanin
  • Stizamet
  • Superlymph,
  • Tykveol
  • Pumpkinol
  • Ulcep
  • Phytostimulin,
  • Mafuta a Rosehip,
  • Ebermin,
  • Eberprot P,
  • Eplan
  • Etaden.

Anayang'aniridwa ndi dokotala wa opaleshoni

Ndimagwiritsa ntchito yankho la Deoxinat makamaka pochiza zilonda zam'mimba za odwala omwe ali ndi mitsempha ya varicose yam'munsi yam'munsi komanso zotupa za odwala. Zovala ziyenera kusinthidwa nthawi zambiri, koma zoyeserera zabwino zimadziwika kale sabata yoyamba yamankhwala. Zomera zatsopano zimawonekera, pamwamba pa zilondazo zimayamba kupindika. Deoxinate amagwiranso ntchito bwino pochiza matenda. Ndipo koposa zonse, machitidwe anga, palibe aliyense wa odwalawa amene adakumana ndi mankhwalawa.

Kutulutsa Fomu

jekeseni 0,5%, wokwanira 5 ml ndi mpeni wokwanira bokosi (bokosi) 10,

Kupanga
1 ml yankho lakumagwiritsa ntchito zakunja lili ndi 0,0025 g wa sodium deoxyribonucleate kuchokera mkaka wa sturgeon, m'mabotolo a galasi 50 ml, mu bokosi la makatoni 1 botolo.

1 ml yankho la jakisoni - 0,005 g, m'mapulogalamu asanu a 5 ml (wokwanira ndi mpeni wokwanira), mu bokosi la makatoni 10 ma PC.

Mankhwala ofanana:

  • Derinat (Derinat) Yankho la jakisoni
  • Solcoseryl Dental Adhesive Paste (Mano yamano)
  • Mafuta a Solcoseryl (Solcoseryl) ogwiritsira ntchito kunja
  • Meturacolum (Spongia "Meturacolum") siponji yapamwamba
  • Mafuta a Iruxol (Iruxol)
  • Derinat (Derinat) Njira yothetsera ntchito zakomweko
  • Galenofillipt (Tincture)
  • Amprovisol (Amprovisol) Aerosol
  • Naftaderm (Naphtaderm) Liniment
  • Mafuta a Proctosan (Proctosan) ogwiritsira ntchito kwanuko ndi kunja

** Maupangiri a Mankhwala ndi a zidziwitso zokha. Kuti mumve zambiri, chonde onani zomwe akupanga. Osadzilimbitsa nokha, musanayambe kugwiritsa ntchito mankhwala a Deoxinate, muyenera kufunsa dokotala. EUROLAB sikuti ali ndi vuto pazotsatira zomwe zimadza chifukwa chogwiritsa ntchito chidziwitso chomwe chatumizidwa pa tsamba. Zomwe zili patsamba lililonse sizilowa m'malo mwa upangiri waudokotala ndipo sizingakhale chitsimikizo cha mankhwala.

Ndimachita chidwi ndi Deoxinate? Kodi mukufuna kudziwa zambiri kapena mukuyenera kukaonana ndi dokotala? Kapena mukufuna kuyesedwa? Mutha kutero pangana ndi adokotala - Euro yachipatala labu nthawi zonse pantchito yanu! Madotolo abwino amayeserera, kukulangizani, kukupatsani chithandizo choyenera ndikupanga matenda. Mukhozanso Itanani dokotala kunyumba. Chipatala cha Euro labu tsegulani kwa inu nthawi yonse yoyandikira.

** Tcheru! Zomwe zawonetsedwa mu bukhuli zamankhwala ndizothandiza akatswiri azachipatala ndipo siziyenera kukhala chifukwa chodzidziwira nokha. Kufotokozera kwa mankhwala a Deoxinate amaperekedwa kuti amve zambiri ndipo sanapangidwe kuti akupatseni mankhwala popanda kutenga dokotala. Odwala amafunikira upangiri waluso!

Ngati mukufunabe mankhwala ndi mankhwala ena aliwonse, mafotokozedwe awo ndi malangizo ogwiritsira ntchito, chidziwitso cha kapangidwe ndi mawonekedwe amamasulidwe, zikuwonetsa ntchito ndi zovuta zake, njira zogwiritsira ntchito, mitengo ndi kuwunika kwa mankhwala, kapena kodi muli ndi mafunso ena ndi malingaliro - tilembereni, tiyesetsa kukuthandizani.

Zizindikiro zogwiritsidwa ntchito

Kuletsa mafupa hematopoiesis (leukopenia, thrombocytopenia) mwa odwala khansa omwe amayamba chifukwa cha cytostatics (mono- kapena polychemotherapy) kapena ophatikizira chemoradiotherapy.

Desoxinate (mwadala): kupewa myelodepression isanayambe kayendedwe ka chemotherapy, makamaka ndikubwereza, mkati mwake ndi pambuyo pake, kuwonetsa padera pa ionizing radiation mu Mlingo womwe umayambitsa kukula kwa luso la radiation II-III.

Derinat (posankha): stomatitis, zilonda zam'mimba komanso zilonda zam'mimba, gastroduodenitis, ischemic mtima matenda, matenda a ischemic matenda a ziwiya zamagawo am'munsi (II-III.), Zilonda zam'mimba za Trophic, mabala osachiritsa, mabala a purulent-septic, amayaka, frostbite , pakukonzekera kwa minofu ya auto- ndi allotransplantation komanso nthawi yolumikizira nthawi yolumikizira, prostatitis, vaginitis, endometritis, kusabereka, kusabala chifukwa cha matenda opatsirana, COPD, pakuchita opaleshoni - nthawi yoyamba komanso yothandizira.

Momwe mungagwiritsire ntchito: Mlingo ndi njira ya chithandizo

Pamaso pa makonzedwe, yankho limakhala lotenthetsera kutentha kwa thupi.

Derinat: mu / m (pang'onopang'ono, mkati mwa mphindi 1-2) ndikutalika kwa maola 24-72.

Akuluakulu - 5 ml (75 mg yowuma). Ndi matenda a mtima a mtima ndi ischemia yamitsempha yamagawo am'munsi, jakisoni wa 5 mpaka 10 umachitika (mlingo pa mankhwala onse ndi 375-750 mg) ndi gawo la masiku atatu.

Ndi zilonda zam'mimba zam'mimba ndi duodenum - jakisoni 5 (mlingo pa mankhwalawa - 375 mg) ndi gawo la maola 48.

Mu matenda a gynecology ndi andrology, mlingo wa maphunzirowo ndi jakisoni 10 (mlingo wa mankhwalawa ndi 750 mg) ndi maola 24-48.

Kuti mulimbikitse leukopoiesis, i / m imaperekedwa 75 mg tsiku lililonse la 2-4, njira ya mankhwalawa ndi jakisoni wa 2-10 (mlingo wa mapiritsi ndi 150-750 mg). Mavuto a radiation akaperekedwa muyezo womwewo tsiku lililonse, mlingo wa maphunzirowo ndi 375-750 mg.

Ana osakwana zaka 2 amafunsidwa kumwa limodzi 0,5 ml (7.5 mg pouma), wazaka 2-10 - 0,5 ml pachaka chilichonse chamoyo.

Desoxinate: mu / m (pang'onopang'ono) kapena s / c, achikulire ndi ana kamodzi - 15 ml ya yankho la 0.5% (75 mg ya chinthu chogwira ntchito). Mobwerezabwereza makonzedwe munthawi yotsatira ya chemotherapy, radiation kapena chemoradiation chithandizo cha odwala khansa amaloledwa. Mankhwalawa pachimake radiation matenda - pasanathe maola 24 kuchokera kukhudzana.

Zotsatira za pharmacological

Imakhala ndi mphamvu ya ma immunomodulatory pama cellular ndi amanyazi. Imayendetsa antiviral, antifungal ndi antimicrobial immune.

Imakhala ndi radioprotective kwenikweni, imathandizira kusinthika: imathandizira kuchiritsa kwa mabala ndi zilonda zam'mimba za pakhungu ndi mucous nembanemba, imayendetsa kukula kwa granulations ndi epithelium.

Iwo ali odana ndi yotupa, antitumor ndi ofooka anticoagulant zotsatira, amateteza chikhalidwe cha zimakhala ndi ziwalo zokhala ndi dystrophy ya mtima.

Amalamulira hematopoiesis (amatanthauzira kuchuluka kwa leukocytes, granulocytes, phagocytes, lymphocyte, mapulateleti).

Kugwiritsa ntchito pachimake radiation matenda II-III zaluso. ndi hypo- ndi aplastic zikhalidwe za hematopoietic dongosolo chifukwa cha radiation kapena polychemotherapy khansa.

Jekeseni wambiri wamitsempha maola 24 atatha mphamvu ya ionizing radiation pa thupi imathandizira matenda a radiation matenda, imathandizira kuyambika ndi kuchuluka kwa tsinde kubwezeretsa maselo mu mafupa, komanso myeloid, lymphoid ndi mapulaneti a hematopoiesis. Zimawonjezera mwayi wazotsatira zabwino zodwala.

Kukondoweza kwa leukopoiesis pambuyo pa jekeseni wa i / m amawonedwa mwa odwala a khansa omwe ali ndi leukopenia III tbsp. ndi zoopsa za IV. (febrile neutropenia) yoyambitsidwa ndi ntchito ya polychemotherapy kapena polychemotherapy yophatikizika. Choyambirira, pali kuwonjezeka kwa kasanu ndi kawiri m'magazi owonjezera a granulocytes, munthawi yomweyo, kuwonjezeka kwamankhwala am'mimba kwambiri komanso kuphatikizika kwa mapulogalamu am'magazi a magazi a zotumphukira za thrombocytopenia a degree ya I-IV omwe adachokera.

Pankhani ya matenda a ischemic am'munsi am'munsi oyambitsidwa ndi atherosulinosis ndi arteritis (kumawonjezera odwala matenda a shuga), zimawonjezera kulolera poyenda, kuthetsa ululu m'matumbo a ng'ombe, kupewa kuziziritsa ndi kuzizira kwamapazi, kumakulitsa kuchuluka kwa magazi m'magawo otsika, kumalimbikitsa kuchiritsa kwa zilonda zam'mimba zam'mimba, mwa odwala ena kumayambitsa kukanidwa kwamtundu wa zala zamitsempha, zomwe zimapewe kuchitapo kanthu.

Monga gawo la kulolerana kovuta, matenda ammtima amathandizanso kukomoka kwa mtima, kumalepheretsa kufa kwa myocyte, kusinthitsa ma cell ochepa m'mitsempha ya mtima, ndikuwonjezera kulolerana kochita masewera olimbitsa thupi.

Imathandizira kusinthika kwa zilonda m'mimba, kumalepheretsa kukula kwa Helicobacter pylori.

Zimawonjezera kukwezedwa kwa ziwonetsero zamagetsi pakukhamukira pakhungu ndi eardrum, kumakulitsa mitsempha yoyambira yamkati mwa ziwalo zamkati.

Amachepetsa kukula kwa zotupa ndikuwonjezera othandizira mphamvu ya cytostatics kapena chemoradiotherapy. Sichimayambitsa mbali yosachedwa kapena yachilendo ndi zotsatira zoyipa, sizikuwonetsa mutagenic, carcinogenic kapena allergenic.

Malangizo apadera

Mu / pakubweretsa yankho sikuloledwa!

Pankhani ya matenda a shuga a mellitus, ndikofunikira kuwongolera kuchuluka kwa shuga panthawi ya chithandizo (kuchuluka kwa hypoglycemia ndikotheka).

Desoxinate: Chizindikiro cha prophylactic ntchito ndi kupezeka kwa leukopenia (osakwana 3.5 chikwi / μl) ndi / kapena thrombocytopenia (150,000 / μl) isanayambike mankhwala ena, leukopenia ndi / kapena thrombocytopenia, omwe adayambika pakumazungulira kwa chemo- kapena chemoradiotherapy (2.5 ndi Mazana zana / μl, motero).

Pankhani ya leukopenia ndi / kapena thrombocytopenia yomwe idachitika panthawi ya chemo / chemoradiotherapy kapena kutha kwake, zikuwonetsa kugwiritsa ntchito mankhwalawa kuchepa pazomwe leukocytes ali m'magazi oyipitsidwa mpaka 2,000 / μl, mapulateleti - 100 zikwi / μl kapena kuchepera.

Pharmacokinetics

Ikagwiritsidwa ntchito timitu tambiri, dexinate imatengedwa ndikugawika ziwalo ndi minyewa ndikugwira nawo gawo la endolymphatic. Mu gawo la kumwa kwambiri magazi kulowa m'magazi, kugaŵananso kumachitika pakati pa madzi am'magazi ndi maselo amwazi, limodzi ndi kagayidwe kachakudya ndi zotupa.

Desoxinate imapangidwa m'thupi. Ma metabolites omaliza ndi xanthine, hypoxanthine, beta-alanine, acetic, propionic ndi uric acids, omwe amachotsedwa m'mimba.

Amachotsa m'thupi (mwa ma metabolites) ndi impso molingana ndi kudalirana kwodabwitsika, mwa gawo lake, kudzera m'matumbo am'mimba.

Zizindikiro Deoxinate

  • Zilonda zoyambirira, mochedwa za poizoni ndi kutentha kwamoto kwa khungu la II-III kwambiri,
  • pachimake radiation pharyngeal syndrome,
  • zilonda zam'mimba
  • kuphwanya umphumphu wa mucous nembanemba wamkamwa, mphuno, nyini, rectum,
  • Zilonda zakale za pakamwa komanso pakhungu,
  • mavuto omwe amachitika ndi cytostatic mankhwala (stomatitis, pharyngoesophagitis, gingivitis, uvulitis, enterocolitis, vulvovaginitis, paraproctitis),
  • pakukonzekera minofu ya auto- kapena allotransplantation komanso panthawi yolumikizira.
Nambala za ICD-10
Khodi ya ICD-10Chizindikiro
I83.2Varicose mitsempha ya m'munsi malekezero ndi zilonda ndi kutupa
L58Dermatitis yoyipa
L89Zilonda za decubital ndi dera la mavuto
T30Mafuta ndi mafuta amayaka, osadziwika
T45.1Mankhwala a antitumor ndi immunosuppressive a poizoni
Z94Kukhalapo kwa ziwalo ndi ziwalo zosaloledwa

Mlingo

Mankhwalawa amalembera ana kuyambira tsiku loyamba la moyo ndi akulu.

Zochizira zilonda zapakhungu, kwezani mavalidwe ndi yankho la Deoxinate, m'malo mwa 3-4 pa tsiku.

Potupa kwa zotupa za pakamwa, ziphuphu zimachitika ndi yankho la Deoxinate (kanayi pa tsiku, 5-15 ml, kenako ndikumeza).

Mu nyini, Deoxinate amatumizidwa pa swab, mu rectum mu enema (20-50 ml).

Kutalika kwa njira ya mankhwala ndikupitirirabe kutha kwa zizindikiro za zotupa ndi zotupa za khungu ndi mucous nembanemba (masiku 4 mpaka 10).

Mankhwala

Deoxinate amawonetsa immunomodulatory zotsatira pama cellular ndi amanyazi. Chidacho chimathandizira kuyambitsa antifungal, antiviral and antimicrobial immune. Imakhala ndi radioprotective kwenikweni, imathandizira kusinthika - imachulukitsa machiritso a mabala ndi zilonda zam'mimba za pakhungu ndi mucous nembanemba, imayambitsa mapangidwe a granulations ndi epithelium. Mukamagwiritsa ntchito njira yothetsera ntchito zakunja ndi zakunja mu mawonekedwe a ntchito, mavalidwe ndi ma rins, zotsatira za analgesic zimadziwikanso, kuopsa kwa zotupa kumachepetsedwa. Chithandizo chogwira hematopoiesis - chimathandizira kuchuluka kwa leukocytes, phagocytes, granulocytes, mapulateleti, lymphocyte. Deoxinate imabweretsa kukulira kwa pulogalamu ya autograft pothandizira pakuwotcha kwaposachedwa, komanso kuphatikizana kwa opaleshoni ya pulasitiki yopunduka ndi zofooka za dera la maxillofacial.

Malinga ndi kafukufuku woyesa, Deoxinate amawonetsa chithokomiro chothana ndi pachimake radiation matenda a II - III digiri yolimba mu hypo- ndi aplastic magawo a m'magazi oyambitsidwa ndi radiation kapena polychemotherapy. Pambuyo pa mankhwala a i / m kamodzi pa mankhwalawa, mphamvu zambiri zomwe zimayambitsa khansa zimawonedwa kwa odwala khansa omwe ali ndi leukopenia wa III ndi madigiri a ngozi ya IV omwe amayamba chifukwa chogwiritsa ntchito polychemotherapy kapena polychemotherapy yophatikizika. Choyambirira, pamenepa, kuwonjezeka kwa mulingo wamagazi apafupipafupi a 5-7 kuchuluka kwathunthu kwama granulocytes kulembedwa. Nthawi yomweyo, chifukwa cha ntchito ya mankhwalawa, kuchuluka kwathunthu kwa ma lymphocyte ndi kusintha kwachulukidwe la kuchuluka kwa maselo othandiza magazi kuundana kumawonedwa ndi thrombocytopenia wa I-IV degree ya genesis yomweyo.

Deoxinate sichikhudza kukula kwa chotupa ndi njira yothandizira ya cytostatics kapena chemoradiotherapy, sizomwe zimayambitsa zotsatira zoyipa msanga kapena kuzengereza, zilibe mutagenic, carcinogenic kapena allergic.

Zotsatira za jakisoni wamtundu wa IM imodzi ya ma immunomodulating othandizira nthawi yoyamba ya maola 24 atatha kuyatsidwa kwathunthu ndi ionizing radiation, njira yachipatala yamatenda a radiation imathandizidwa poyesa, kuyambira ndi kubwezeretsa kwa maselo a tsinde m'mphepete mwa mafupa, komanso lymphoid, myeloid ndi platin hematopoiesis.

Chifukwa cha machitidwe a mankhwalawa, kuthekera kwa zotsatira zabwino za matenda a radiation kumawonjezeka. Zotsatira zabwino zochizira za Deoxynate zimawonedwa pachimake pharyngeal syndrome, kuwotcha kwamoto, zilonda zam'mbuyo komanso mochedwa, komanso zovuta zokhudzana ndi cytostatic chithandizo.

Yankho la i / m ndi s / c kasamalidwe

  • kwambiri myelodepression (leuko- ndi thrombocytopenia) mwa odwala khansa, chifukwa cha cytostatics (mono- kapena polychemotherapy) kapena kuphatikiza chemoradiotherapy (chithandizo),
  • leuko- ndi thrombocytopenia wapezeka m'mbuyomu chemo- kapena chemoradiotherapy, kukhalapo kwa thrombocytopenic (osakwana 150x10 9 / l) ndi leukopenic (osakwana 3,5x10 9 / l) maziko asanayambike mwatsatanetsatane - kupewa, mankhwala kapena mankhwala a chemoradiation, makamaka mobwerezabwereza, mkati mwake kapena itatha, ndi leukopenia ndi / kapena thrombocytopenia yomwe idayamba pa nthawi ya chemotherapy (chemoradiotherapy) kapena itatha, chisonyezo chogwiritsidwa ntchito Pokonzekera mankhwalawa kuchepa kwa magazi m'magazi a leukocytes mpaka 2x10 9 / l, maselo othandiza 100x10 9 / l kapena kuchepera.

Malinga ndi kafukufuku woyesera, Deoxinate amasonyezedwanso kwa odwala omwe ali ndi chidziwitso chowopsa cha radiation mu Mlingo womwe umatsogolera kukula kwa matenda a radiation a II - III digiri.

Njira yothandizira ntchito zakunja ndi zakunja

  • pachimake radiation pharyngeal syndrome,
  • Zilonda zoyambirira, mochedwa za poizoni ndi kutentha kwamoto kwa khungu la II - III digiri,
  • zilonda zam'mimba
  • Zilonda zakale za pakamwa komanso pakhungu,
  • kuphwanya umphumphu wa mucous nembanemba wamkamwa, mkamwa, rectum, nyini,
  • mavuto omwe amachitika ndi cytostatic mankhwala: gingivitis, pharyngoesophagitis, uvulitis, stomatitis, enterocolitis, paraproctitis, vulvovaginitis,
  • Ankalumikiza nthawi, kukonzekera minofu ya auto- kapena allotransplantation.

Contraindication

Kutsutsana ndi kugwiritsa ntchito Deoxinate ndiko kusalolera kwamtundu uliwonse wa zigawo zake.

Kuphatikiza apo, yankho la kugwiritsa ntchito zakunja ndi zakunja silikulimbikitsidwa kwa amayi apakati komanso oyamwitsa.

Mosamala komanso pokhapokha ndikaonane ndi dokotala ndikuwunika mosamala maubwino omwe mungagwiritsidwe ntchito pochiritsa mayi ndikuwopseza thanzi la mwana wosabadwayo, njira yothetsera i / m ndi s / c ikhoza kugwiritsidwa ntchito panthawi yoyembekezera. Panthawi yoyamwitsa, mtundu uwu wa mankhwalawa ungagwiritsidwe ntchito mosamalitsa monga adanenera dokotala.

Zotsatira zoyipa

Mu / m ndi s / c kasamalidwe ka Deoxinate sikubweretsa zovuta. Nthawi zina, maola 4 mpaka 24 jekeseni atatha jekeseni yocheperako (osaposa maola 2 - 2), kuchokera pazowonjezera zochepa mpaka 38,5 ° C, nthawi zambiri popanda kuwonjezera vuto la wodwalayo (kuziziritsa, ndi zina) komanso osafuna kuwongoleredwa. Pankhani ya kukakamizidwa kukhazikitsa yankho, kupweteka kwapafupi ndi jakisoni ndikotheka, komwe sikutanthauza kuti pakhale mankhwala.

Ikagwiritsidwa ntchito kwanuko, wothandizirana ndi ma immunomodulatory sayambitsa chitukuko cha zochitika zoyipa.

Ngati zilizonse zomwe tatchulazi zakula, kapena vuto lina lililonse likawoneka motsutsana ndi kugwiritsidwa ntchito kwa Deoxinate, muyenera kufunsa dokotala.

Mimba komanso kuyamwa

Njira yothetsera kugwiritsa ntchito zakunja ndi kunja sizikulimbikitsidwa kwa amayi apakati komanso oyamwitsa.

Njira yothetsera i / m ndi s / c pa nthawi yoyembekezera ingagwiritsidwe ntchito pambuyo pofunsa dokotala ndikuwunikira mosamala zabwino zomwe zingachitike pochiritsa mayi komanso zomwe zingawopseze thanzi la mwana wosabadwayo. Panthawi yoyamwitsa, mawonekedwe a Desoxinate angagwiritsidwe ntchito mosamalitsa monga adanenera dokotala.

Kuyanjana kwa mankhwala osokoneza bongo

Pamene ine / m ndi s / kumayambiriro, deoxinate amatha kuonetsa mphamvu ya ma cytostatics ndi antitumor mankhwala - anthracyclines.

Ikagwiritsidwa ntchito mopitirira, mankhwalawa sangaphatikizidwe ndi mayankho a hydrogen peroxide ndi mafuta onunkhira oikidwa m'mafuta.

Mndandanda wa Deoxinate ndi Derinat, Panagen, Sodium deoxyribonucleate, Ridostin, etc.

Ndemanga pa Deoxinate

Makonda a deoxyninate pamankhwala azachipatala ndi ochepa. Odwala ambiri anali okhutira ndi mankhwalawa, makamaka pamtundu wa yankho la ntchito zapamwamba ndi zakunja, ndipo amakhulupirira kuti zimakwaniritsa njira yothandizira. Amadziwika kuti mankhwalawa adziwonetsa okha pochiza matenda a stomatitis, zilonda zam'mimba, zilonda zam'mimba, mabala amiseche, ma ENT pathologies, adhesions, aakulu endometritis. Yankho la Deoxinate mu ampoules (kwa i / m ndi s / c makulidwe), malinga ndi ndemanga za odwala, adawonetsa zotsatira zabwino pa mankhwala a leukopenia. Mu kuwunika kwa akatswiri, mankhwalawa amatchedwa njira yothandiza kwambiri yoyambitsa matenda a radiation.

Komabe, palinso madandaulo a odwala omwe amawonetsa kuti ali ndi kachipatala kochepa kamene kamathandizira, komanso kukula kwa zoyipa ndi kupweteka pamalo a jekeseni wa intramuscular. Nthawi zambiri pamakhala kusowa kwa mankhwalawo m'mafakisi.

Mtengo wa deoxinate m'mafakisi

Mtengo wa Desoxinate sukudziwika chifukwa chakuti mankhwalawa sapezeka muukonde wa mankhwala.

Mtengo wa analogue ya mankhwalawa, Derinat, yankho la kugwiritsira ntchito zakunja ndi zakunja za 0.25%, zitha kukhala ma ruble a 208-327. pa botolo la 10 ml. Derinat mu njira yothetsera mu mnofu makonzedwe a 15 mg / ml zitha kugulidwa kwa 1819-2187 rubles. pa paketi imodzi ya mabotolo 5 a 5 ml.

Kusiya Ndemanga Yanu