Chithandizo cha Roxer Cholesterol
Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.
Matenda a shuga masiku ano akuimira vuto lalikulu m'gulu la asayansi apadziko lonse lapansi, popeza kuchuluka kwawo kufikira kale pa 7% yaanthu onse padziko lapansi. Matendawa sangathe kuchiritsidwa kwathunthu ndipo ndiwowopsa chifukwa amalemedwa ndimatenda oyamba. Nthawi zambiri, mwa odwala, mtima dongosolo limadwala, omwe amalumikizidwa ndi kolesterol yowonjezereka m'magazi, kuwonongeka ndi kutsekeka kwamitsempha yamagazi ndi mapepala.
Koma matenda ashuga okha si chiganizo, chifukwa asayansi apanga njira zabwino zothandizira wodwalayo kuti akhalebe wathanzi komanso labwino. Kuti izi zitheke, wodwalayo ayenera kutsatira zakudya zinazake, azichita masewera olimbitsa thupi komanso kumwa mankhwala ena ake.
Posachedwa, ma statins akhala akugwiritsidwa ntchito pazamankhwala kuti athane ndi matenda a shuga. Komabe, madokotala akadali kutsutsana za momwe mankhwalawa amagwira ntchito komanso osavulaza, popeza mndandanda wosangalatsa wazotsatira zake umapangitsa madokotala ndi odwala kuganiza za momwe amagwiritsidwira ntchito.
Cholesterol ndi shuga
Asayansi adziwa kwanthawi yayitali kudalira kwa kuchuluka kwa shuga ndi magazi. Pakati pa matenda a shuga, zomwe zimakhala ndi glucose zimachulukirachulukira, koma zimapangitsa kuchuluka kwa lipid osati mwachindunji, koma osati. Popeza kusintha kwamankhwala kumakhala magazi mwa odwala, impso ndi chiwindi zimavutika nthawi zonse, ndipo izi zimakwiyitsa cholesterol.
Mpaka 80% yazinthu izi zimapangidwa m'thupi la munthu, 20% yotsalayo imachokera muzakudya zomwe zadyedwa. Pali mitundu iwiri ya triglycerides:
- madzi sungunuka ("chabwino"),
- imodzi yomwe siyisungunuke mu zakumwa ("zoyipa").
Cholesterol yoyipa imatha kudziunjikira pamakoma a mtima, ndikupanga zolembera. Zotsatira zake, wodwala yemwe ali ndi matenda a shuga, omwe ali ndi lipid yambiri m'magazi, ali ndi chiwopsezo chachikulu chotenga matenda a atherosclerosis, omwe ali ofala kwambiri chifukwa cha matenda ashuga. Kuphatikiza apo, zolembera za cholesterol zimayambitsa kuchepa kwa kama wamitsempha ndikusokonekera kwa magazi. Kusintha kotereku m'magazi kumatha kudzetsa matenda a stroko kapena mtima.
Pazifukwa izi, ndikofunikira kuti odwala matenda ashuga azilamulira mafuta m'thupi, omwe angachepetse chiopsezo chokhala ndi matenda amtima. Pazifukwa izi, odwala matenda a shuga, makamaka akapezeka ndi mtundu wachiwiri, amapatsidwa mankhwala monga gawo la zovuta mankhwala. Kugwiritsa ntchito kumakupatsani mwayi wokhala ndi lipid metabolism, zomwe zimapangitsa kupewa zovuta zina zaumoyo.
Kodi ma statins ndi omwe amagwira ntchito bwanji?
Statin ndi gulu la mankhwala omwe ali ndi lipid-yotsika - amachepetsa cholesterol yamagazi. Makina awo akuchita motere: ma statins amatseka zochita za enzyme yotchedwa HMG-CoA. Yotsirizira iyi imayang'anira lipid biosynthesis m'maselo a chiwindi. Enzyme iyi ikatsekedwa, kapangidwe ka cholesterol m'chiwindi chimachepetsedwa kwambiri. Ili ndiye ntchito yayikulu yama statins.
Mevalonic acid imathandizanso pakupanga mankhwala a cholesterol. Ndiwe m'modzi amalumikizano oyamba motere. Statins imaletsa kaphatikizidwe kake, motero, kupanga lipids kumachepetsedwa.
Chifukwa cha kuchepa kwa mulingo wake m'mwazi, makina olumikizira adakonzedwa: ma receptor omwe amapezeka pamwamba pa maselo amakhala omvera kwambiri mafuta m'thupi. Izi zimapangitsa kuti pakhale zochulukirapo kuti ma membrane receptors adze, chifukwa, cholesterol yomwe ilipo m'magazi imatsitsidwanso.
Kuphatikiza apo, mankhwalawa ali ndi zotsatira zina mthupi:
- muchepetse kutupa m'matumbo, omwe amathandiza kuti malo azikhazikika,
- amakulolani kusintha kagayidwe kachakudya mthupi,
- amathandizira kuti magazi aziwonda, zomwe zimapangitsa kuti chiwopsezo chopanga mapangidwe azigawo azisungunuka m'mitsempha yamagazi,
- amathandizira zolembera za atherosulinotic mu khola, mukakhala chiopsezo chochepa kwambiri chodzipatula
- Kuchepetsa kuyamwa kwa mafuta m'matumbo a cholesterol
- imalimbikitsa kupanga nitric oxide, yomwe imalimbikitsa ziwiya kuti zizipuma komanso zimapangitsa kufupika pang'ono.
Chifukwa cha zovuta zake, ma statins amafunsidwa kuti mupewe kugunda kwa mtima ndi matenda a mtima, amakulolani kuchira msanga mukakumana ndi vuto la mtima. Gulu la mankhwalawa ndilofunikira kwa odwala omwe ali ndi atherosulinosis, popeza ma statins amatha kubwezeretsa endothelium (mkati mwake) yamitsempha yamagazi, makamaka m'mayambiriro a matendawa, pomwe munthu samamvanso zizindikiro za atherosclerosis ndipo sangadziwike, koma mawonekedwe a cholesterol pamakoma a mtima ayamba kale. Gawani odwala omwe ali ndi matenda a shuga komanso matenda ena omwe amadziwika ndi chiopsezo chowonjezeka cha atherosulinotic pathologies.
Matenda ndi matenda ashuga
Matenda a shuga ndi matenda achilengedwe, omwe amadziwika ndi kuchuluka kwa ma concomitant pathologies. Zotsatira zoyipa kwambiri ndizo matenda a mtima ndi mtima, omwe amawoneka motsutsana ndi kuwonongeka kwa mitsempha. Komabe, ndi chisamaliro choyenera, mawonekedwe ndi kutalika kwa nthawi zimatha kusintha. Chimodzi mwazomwe zimapangitsa kagayidwe kachakudya mu thupi ndi ma statins. Amakhudza metabolism yamafuta, yomwe ndiyofunikira kwambiri mtundu wa 2 matenda.
Ntchito yayikulu ya mankhwalawa, yomwe amathandizira odwala matenda ashuga, ndikuletsa kukula kwa zovuta kuchokera ku mtima: kuvulala, kugunda kwa mtima komanso atherosclerosis.
Malingaliro a mabungwe apadziko lonse lapansi, aku Europe ndi ku nyumba zamankhwala pamankhwala omwe amapezeka kwa odwala omwe ali ndi matenda osokoneza bongo amagwira ntchito kwa odwala ambiri omwe ali ndi vutoli:
- Statins ndikusankha koyamba ngati wodwala yemwe ali ndi matenda a shuga ali ndi LDL cholesterol wamkulu kuposa 2 mmol / L.
- Kwa odwala matenda ashuga omwe apezeka ndi matenda a mtima, kugwiritsa ntchito mankhwalawa ndizovomerezeka mosasamala kuchuluka koyamba kwa lipids m'magazi.
- Chithandizo chofananacho kwa odwala omwe ali ndi mtundu wa 2 matenda a shuga omwe sapezeka ndi ischemia amayenera kufotokozedwa pamene kuchuluka kwa cholesterol kumadutsa malire a 3.5 mmol / L.
- Muzochitika zomwe chithandizo cha mankhwala okhala ndi ma statins pazovomerezeka kwambiri sichinayambitse kuchuluka kwa triglycerides kukhala yokhazikika (ochepera 2 mmol / l), chithandizo chimathandizidwa ndi nicotinic acid, fibrate kapena ezetimibe.
Ndi ma statins omwe ndi abwino kwambiri kwa matenda ashuga
Pazovuta za odwala otere, madokotala nthawi zambiri amagwiritsa ntchito Rosuvastatin, Atorvastatin ndi Simvastatin. Ngati mumayerekezera awa atatu odziwika, ndiye kuti mbadwo waposachedwa, Rosuvastatin, amakhala mtsogoleri wopanda vuto lililonse. Amachepetsa kwambiri cholesterol "yoyipa" - mwa 38%, ndipo malinga ndi ena, chiwerengerochi chimafika pa 55%. Nthawi yomweyo, kuchuluka kwa madzi osungunuka a lipids kumawonjezeka ndi 10%, zomwe zimakhudza kagayidwe kokwanira ka mafuta m'thupi.
Simvastatin ndi Atorvastatin ali m'mbuyo pang'ono potengera izi. Oyamba amachepetsa kuchuluka kwa triglycerides ndi 10-15% ("yoyipa" cholesterol imatsika ndi 22), ndipo yachiwiri ndi 10-20% (kuchuluka kwa mafuta osakwanira amatsika ndi mfundo 27). Zizindikiro zofananazi zidadziwika ku Lovastatin, yomwe nthawi zambiri imafotokozedwa ndi madokotala aku Russia.
Mbali yabwino ya Rosuvastatin ndikuti muumboni wake pali kuchuluka kwa mapuloteni a C-reactive - chinthu chomwe chimadziwika ndi kutupa kwakatundu m'matumbo. Chifukwa chake, rosuvastatin amatha kusamalira zolembera zomwe zilipo m'khola.
Mankhwala, mankhwalawa amatha kupezeka m'mazina azamalonda awa:
Mankhwala achiwiri odziwika komanso othandiza - Atorvastatin - akhoza kupezeka pansi pa mayina awa:
- Atorvastatin Canon,
- Atomax
- Atoris
- Liptonorm,
- Liprimar
- Tulip
- Torvacard.
Kuti mumvetsetse mphamvu ndi ma statins, mungathe kuwaganizira monga momwe mibadwo yamankhwala ilili:
Musaganize kuti zolengedwa zachilengedwe ndizabwino kuposa zopangidwa. Malinga ndi malipoti ena, akale anali ndi zotsatira zoyipa kuposa ma statin, omwe ali ndi "chemistry" yokhayo.
Ndikofunikira kudziwa kuti ma statins onse ndi omwe mumalandira mankhwala, chifukwa chake simungasankhe nokha mankhwala. Ena mwa iwo atha kukhala ndi zotsutsana zosiyanasiyana, chifukwa chake musafunse dokotala kuti akupatseni mankhwala abwino mu malingaliro anu. Munthawi zonsezi, mankhwalawa amasankhidwa payekhapayekha, poganizira mawonekedwe a thupi la wodwalayo.
Kodi ndimankhwala ati omwe angathandize ndi matenda a shuga a 2
Matenda amtunduwu ali ndi chiopsezo chachikulu chotenga matenda a mtima - 80% motsutsana ndi 40% ya matenda amtundu 1. Pazifukwa izi, mankhwala a statin ndi gawo limodzi la chithandizo chofunikira cha odwala. Amalola kupewa koyambira komanso kwachiwiri kupewa matenda a mtima komanso kuwonjezera kuchuluka kwa moyo wa odwala. Kugwiritsa ntchito ma statins ndikofunikira kwa odwala oterewa ngakhale atakhala kuti sanapezeke ndi matenda a mtima kapena cholesterol ali mkati moyenera.
M'maphunziro angapo, zidadziwika kuti kwa odwala ambiri omwe ali ndi matenda amtundu wa 2, kuchuluka kwa mankhwalawa tsiku lililonse, komwe kunali kothandiza pa matenda a matenda a shuga 1, sikunathandize. Chifukwa chake, mankhwalawa a mtundu wachiwiri wa shuga, mitundu yayikulu yovomerezeka ya mankhwala imagwiritsidwa ntchito masiku ano:
- kwa atorvastatin ndi pravastatin, tsiku lililonse sayenera kupitirira 80 mg,
- kwa rosuvastatin ndi pravastatin - osaposa 40 mg.
Kafukufuku wambiri wamabungwe azachipatala a 4S, DECODE, CARE, HPS ndi ena akhazikitsa mgwirizano pakati pa kugwiritsidwa ntchito kwa ma statins odwala omwe ali ndi matenda amtundu wa 2 komanso kuchepetsedwa kwa zovuta ndi kufa kwa matenda a mtima chifukwa cha kuchuluka kwa matenda a mtima. Chifukwa chake, Pravastatin adawonetsa zabwino - kufa kumatsika ndi 25%. Pambuyo pa kudya kwa Simvastatin kwa nthawi yayitali, asayansi adalandira zotsatira zofanana - 25% yomweyo.
Kafukufuku wokhudzana ndi kugwiritsidwa ntchito kwa Atorvastatin adawonetsa zotsatirazi: kufa kwatsika ndi 27%, pomwe chiwopsezo chodwala chatsika ka 2. Kafukufuku wofanana wa Rosuvastatin sanatulutsidwebe, chifukwa mankhwalawa adawoneka posachedwa pamsika wazamankhwala. Komabe, asayansi apakhomo amachitcha kuti abwino kwambiri pankhani yochepetsa cholesterol, popeza zikuwonetsa kuti magwiridwe antchito ake amafika 55% kale.
Ndizofunikira kudziwa kuti pankhaniyi ndizosatheka kudziwa kuti ndi maulosi ati omwe ali bwino kwa odwala omwe ali ndi mtundu uwu wa matendawa, chifukwa chithandizo chimasankhidwa payekhapayekha, ndikuganizira zambiri za thupi ndi kapangidwe kazinthu zamagazi.
Matenda a shuga a Type 2 ndi ovuta kuchiza ndipo kugwiritsa ntchito ma statins sikungapereke zotsatira zowoneka mpaka miyezi iwiri. Chithandizo chokhazikika komanso chokhazikika chomwe gulu ili limakupatsani chimakhala chotsatira.
Crestor kapena Roxer: ndibwino kwa cholesterol?
- Imakhazikika pamisempha ya shuga kwa nthawi yayitali
- Imabwezeretsa kapangidwe ka insulin
Cholesterol chachikulu pakadali pano chitukuko cha anthu ndichimodzi mwazinthu zovuta kwambiri m'badwo wakale. M'zaka zaposachedwa, kupezeka kwa cholesterol yochulukirapo kumawonekera kwambiri m'badwo wachichepere.
Zomwe zimapangitsa kukonzanso kwa matendawa ndizomwe zimachitika pafupipafupi kupsinjika kwamaganizidwe a thupi, kuphwanya chikhalidwe, kudya zakudya zambiri zomwe zimakhala zoopsa, komanso kutsogolera moyo wongokhala. Zinthu zonsezi zimayambitsa kusokonekera kwa metabolic m'thupi.
Kuti athetse vuto la pathological lomwe likubwera, amafunika kusankha mankhwala abwino komanso othandiza pakubwezeretsanso magazi a plasma cholesterol.
Kuchepetsa cholesterol yayikulu mthupi, madokotala nthawi zambiri amalimbikitsa kugwiritsa ntchito mankhwala omwe ali m'gulu la ma statins.
Odziwika kwambiri ndi mankhwala awiri a gululi - Krestor kapena Roxer.
Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.
Mankhwala ochepetsa awa a lipid amapangidwa ndi opanga momwe amapangira mapiritsi amkamwa.
Kuti mugwiritse ntchito moyenera, muyenera kudziwa Roxer kapena Atorvastatin omwe ali bwino, kuwonjezera pa funsoli, odwala amakhalanso ndi funso lazomwe zili bwino kuposa Rosucard kapena Roxer. Kutuluka kwa mafunso awa kumalumikizidwa ndi kutchuka kwambiri ndalamazi ndindalama zothandizira kuchepetsa lipid.
Chovuta pakusankha mankhwala oyenera ndikuti onse ali ndi zotsatira zofanana pa thupi la wodwalayo. Pachifukwa ichi, ndi adokotala okhawo omwe amatha kusankha njira yabwino kwambiri yamankhwala malinga ndi zotsatira za mayeso ndikuzindikira mawonekedwe a thupi la wodwalayo.
Zolemba za Crestor
Mtanda ndi mankhwala oyamba okhala ndi milomo yotsitsa lipid. Kugwiritsa ntchito mankhwalawa kumatha kuchepetsa cholesterol yathunthu, lipoproteins yotsika komanso triglycerides.
Mankhwalawa ndi mpikisano wosankha wa HMG-CoA reductase. Enzyme iyi imayang'anira kutembenuka kwa 3-hydroxy-3-methylglutarylcoenzyme A mpaka mevalonate, komwe ndiko kutsogolo kwa mowa wa polycyclic lipophilic.
Cholinga chachikulu cha kupezeka kwa mankhwalawa ndi hepatocytes a chiwindi, momwe kapangidwe ka cholesterol ndi LDL catabolism zimachitikira.
Mukamagwiritsa ntchito mankhwalawa, mawonekedwe a achire amawonedwa sabata limodzi pambuyo poyambitsa makonzedwe.
Kuchuluka kwake kumatheka pofika kumapeto kwa mwezi wa chithandizo.
Excretion ya Crestor imachitika kuchokera mthupi mu mawonekedwe osasinthika ngati gawo la ndowe. Pafupifupi 90% ya mankhwala omwe amagwira ntchito amapezeka m'matumbo. 10% yotsalayi imachotsedwa ndi impso mkodzo.
Chizindikiro chogwiritsira ntchito mankhwala ndi:
- kupezeka kwa wodwala yemwe ali ndi hypercholesterolemia malinga ndi Fredrickson,
- wodwala ali ndi homozygous hypercholesterolemia,
- kuzindikira kwambiri hypertriglyceridemia m'thupi la munthu,
- kugwiritsa ntchito mankhwalawa monga chinthu chomwe chimachepetsa kupitilira kwa atherosulinosis.
Mukamagwiritsa ntchito mankhwalawa, chinthu choyambirira ndichofunika kuti muzitsatira zakudya zomwe zimapangitsa kuchepetsa ululu wa lipid.
Zoyeserera pakugwiritsa ntchito Crestor ndi izi:
- Matenda a chiwindi mu gawo yogwira.
- Kusokonekera mu ntchito ya impso.
- Myopathy
- Kulandila kwa cyclosporine ngati othandizira.
- Nthawi ya bere ndi kuyamwitsa.
- Hypersensitivity pamagawo a mankhwala.
Mosamala, mankhwalawa amagwiritsidwa ntchito pamene wodwala amamwa zakumwa zoledzeretsa komanso pankhani ya mankhwala atakalamba, ndi wodwala wopitilira zaka 65.
Mankhwala osokoneza bongo amatha kuchitika makamaka munthawi yomweyo Mlingo wambiri.
Palibe mankhwala enieni, ndipo chithandizo chimachitika ngati chiri chofunikira, ndikuyang'anira ntchito ya ziwalo zofunika kwambiri za anthu.
The zikuchokera mankhwala, njira ntchito ndi Mlingo
Chofunikira chachikulu pa Crestor ndi rosuvastatin. Katunduyu ali ndi mphamvu yochepetsa lipid. Kuphatikiza apo, mapangidwe a mapiritsiwa ali ndi mitundu yonse ya mankhwala omwe amathandizira.
Kumwa mankhwalawa molingana ndi malangizo ogwiritsira ntchito kumatha kuchitika nthawi ina iliyonse masana. Piritsi imatengedwa pakamwa, osatafuna ndikusambitsidwa ndi madzi okwanira. Mlingo woyambirira wa mankhwalawa ndi 5 mg. Ngati ndi kotheka, kusintha kwa Mlingo wogwiritsidwa ntchito kumachitika mwezi umodzi chiyambireni chithandizo.
Mukamasankha mlingo woyambirira, munthu ayenera kutsogoleredwa ndi zotsatira za kafukufuku wa wodwala pazomwe zimakhala m'mafuta a m'magazi. Kuphatikiza apo, posankha mtundu wa mankhwalawa, ndikofunikira kuyesa momwe zingakhalire ndi zotsatirapo zake.
Pochiza odwala a mtundu wa Mongoloid, mlingo woyambirira wa mankhwalawa ndi 5 mg.
Ngati wodwalayo amakonda kukula kwa myopathy, ndiye kuti mlingo woyambayo wa mankhwalawo umaloledwa
Mukamagwiritsa ntchito mankhwalawa, wodwala amatha kukumana ndi mavuto osiyanasiyana.
Nthawi zambiri, mavuto obwera chifukwa chogwiritsa ntchito Krestor amawonetsedwa ndi dongosolo lamanjenje lamkati, m'mimba, khungu, minofu ndi mafupa.
Mafuta a mankhwalawa ndi awa:
- Mertenil
- Rosuvastatin SZ,
- Rosart,
- Tevastor
- Rosucard,
- Rosicore
- Rosulip,
- Rustor
- Roxer ndi ena.
Mtengo wa Krestor ndi mawonekedwe ake amatha kusiyanasiyana kutengera dera la dzikolo komanso mtundu wa mankhwala omwe wagulidwa ndi wodwala.
Kutsika mtengo kwambiri, koma nthawi yomweyo, analogue yabwino ya Crestor - Akort. Mtengo wa mankhwalawa ndi pafupifupi ma ruble 511.
Poyerekeza ndi mtengo wa mankhwala oyambira pafupifupi ma ruble 1,676, ndiwotsika kuposa katatu.
Zolemba za Roxer ya mankhwala
Roxera ndi mankhwala amphamvu a hypolipidemic. Chofunikira chachikulu pa mankhwalawa ndi rosuvastatin.
Chizindikiro chogwiritsa ntchito mankhwalawa ndi kupezeka kwa wodwala wa hypercholesterolemia m'njira zosiyanasiyana - zoyambirira komanso zosakanikirana.
Roxera amagwiritsidwanso ntchito pochiza matenda monga atherosulinosis. Kugwiritsa ntchito mankhwalawa kumalepheretsa kukula kwa zovuta zazikulu zomwe zimakhudzana ndi cholesterol yayikulu m'madzi a m'magazi.
Omwe amadziwika kwambiri ndi anzawo a Roxer pakati pa odwala ndi mankhwala monga Atoris ndi Krestor.
Mu mankhwalawa, pawiri yogwira popanga ndizofanana - rosuvastatin.
Roxera ndi mankhwala opangidwa ndi akatswiri azamankhwala ku Russia.
Roxera amapezeka mu mawonekedwe a mapiritsi ofunikira pakamwa.
Mapiritsi a mankhwalawa amatengedwa pakamwa ndikutsukidwa ndi madzi okwanira.
Mlingo Roxers wogwiritsidwa ntchito mankhwalawa ndiwofanana ndi omwe amagwiritsidwa ntchito pochiza Crestor.
Contraindication kuti agwiritse ntchito ndi awa:
- Hypersensitivity ku gawo lalikulu kapena mankhwala othandizira.
- Nthawi ya bere ndi nthawi yoyamwitsa.
- Zaka za wodwalayo zili ndi zaka 18.
- Wodwala amakhala ndi lactose tsankho komanso kuchepa kwa thupi la lactase.
- Myopathy
- Kulephera kwamkati ndi chiwindi.
Pankhani yogwiritsa ntchito mankhwalawa, n`zotheka kukulitsa mavuto obwera ndi chizungulire, kupweteka mutu, zotupa pakhungu, jaundice, chiwindi, kuiwala kukumbukira, kupweteka pamimba, kudzimbidwa komanso kutsegula m'mimba, nseru, myopathy.
Zofanizira zazikulu za Roxers pazogwiritsa ntchito ndi:
Mndandanda wa mankhwalawa, omwe ali m'gulu la ma statins, ndi Zokor, Vazator, Lipona. Lipostat, Apextatin ndi njira zina.
Kusiyana kwakukulu pakati pa Crestor ndi Roxer
Kuti muyankhe funso lomwe mankhwala a Krestor kapena Roxer ali bwino, amafunikira kuti aphunzire kusiyana kwakukulu pakati pa mankhwalawo.
Mankhwalawa onse ndi a gulu limodzi ndipo ali ndi chiwalo chimodzi chomwe chikugwira ntchito, kusiyana pakati pa mankhwalawo kumagona pazinthu zothandizirana zomwe zimagwiritsidwa ntchito ngati mankhwala. Mankhwalawa onse amachepetsa mulidi wa lipids m'thupi la wodwalayo.
Mukamasankha mankhwala, kusiyana komwe kulipo pakati pa mankhwala, omwe ali motere:
- Roxer amatha kudziunjikira pachithandizo chamankhwala motero mphamvu zoyenera zimawonekera mukamagwiritsa ntchito mankhwala kumapeto kwa sabata lachiwiri lokonzekera. Mtanda ndi mankhwala omwe zochita zake zimathamanga mwachangu, zotsatira zake zikuwoneka kale patsiku la 5 kugwiritsa ntchito mankhwalawo.
- Mukamamwa Krestor wodwala, kukula kwa matenda ashuga a 2 ndikotheka. Pankhani yogwiritsa ntchito mankhwala apakhomo, kuphwanya mbali kotereku sikumawonedwa.
- Chithandizo cha kunyumba chimatha kupangitsa kuti mapuloteni awoneke poyesa magazi, pomwe kufotokoza kwakeko sikuyambitsa kuphwanya.
- Mtanda ukhoza kugwiritsidwa ntchito ndi odwala omwe ali ndi zaka 18, ndipo mankhwala am'nyumba ndi oletsedwa kugwiritsidwa ntchito mpaka zaka 18.
Mukamagwiritsa ntchito limodzi komanso mankhwalawa, muyenera kudya zakudya zowonjezera za hypolipedymic ndi kuwongolera kowonjezera magwiridwe antchito a chiwindi.
Musanaganize kusankha mankhwalawa, ndikulimbikitsidwa kuti mufunsane ndi dokotala kuti mudziwe kuwunika kwa madokotala ndi odwala za amodzi ndi amodzi.
Ndemanga za kugwiritsidwa ntchito kwa mankhwala omwe mwalowetsedwa nthawi zambiri amatsala ndi odwala omwe ali ndi vuto la atherosulinosis. Malinga ndi iwo, kugwiritsa ntchito mankhwalawa kumakupatsani mwayi wowonjezera nthawi yochulukirapo komanso kuchepetsa kuchuluka kwa zomwe zimachitika, ndipo kugwiritsa ntchito mankhwalawa nthawi zina kumapeweka kuchipatala.
Malinga ndi odwala, kugwiritsa ntchito mankhwala osokoneza bongo kumalumikizidwa ndi kupezeka kwa zotsatira zoyipa zosiyanasiyana mwa wodwala. Zotsatira zoterezi m'thupi la wodwalayo zimayambitsa zosowa zachilendo za Krestor.
Ndingatenge ma statins ndikamuuza katswiri mu kanemayu munkhaniyi.
- Imakhazikika pamisempha ya shuga kwa nthawi yayitali
- Imabwezeretsa kapangidwe ka insulin
Aterol kuti muchepetse cholesterol
Kwa zaka zambiri osavutika ndi CHOLESTEROL?
Mutu wa Bungwe: “Mudzadabwa momwe zimakhalira zosavuta kuchepetsa mafuta m'thupi mwakumwa tsiku lililonse.
Aterol (Aterol) kuchokera ku cholesterol - mankhwala omwe amathandizira kuchotsa poizoni wakupha, matenda kuchokera mthupi. Komanso, mankhwalawa amayamba kuchita nthawi yomweyo. Kale patsiku lachiwiri zotsatira zake zikuwoneka. Chifukwa chakuti cholesterol idzachotsedwa msanga, kulemera kumayamba kuchepa nthawi yomweyo.
Palibe anthu omwe sangamve za cholesterol "yoyipa". Ndizowopsa chifukwa imatha kuyikika pazitseko zamitsempha yamagazi, ndikupanga cholesterol plaque. Nawonso, amatsogolera pakupanga kwa magazi. Cholesterol chovulaza ndi chomwe chimayambitsa thrombophlebitis, stroko, mtima. Mwa kutenga Aterol, zovuta izi zitha kupewedwa.
Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.
Kodi mankhwalawa ndi othandiza motani?
Aterol ndi mankhwala osinthira nkhondo yolimbana ndi cholesterol yoopsa. Fomula yamankhwala yapangidwa kwazaka zambiri. Mankhwalawa adadutsa maphunziro onse ofunikira ndipo wavomerezedwa kuti azigulitsidwa ku Russia. Maziko a mankhwalawa ndi ma probiotic.
Mavuto a cholesterol okwanira amapezeka nthawi zambiri mwa amuna. Mthupi la azimayi, timapangidwa timadzi tomwe timatulutsa magazi omwe amathandiza kuyeretsa magazi. Chifukwa chake, kwa amuna, Aterol ndiye chipulumutso chenicheni. Makamaka patatha zaka 40. Mankhwala angapo ophatikizira matenda oopsa amatha kungochotsa zisonyezo za matendawa, osakhudza zomwe zimayambitsa matenda oopsa. Koma zolembera za cholesterol ndi zina mwazomwe zimayambitsa matenda amtima wamthupi komanso kunenepa kwambiri. Aterol imakhudza chifukwa chachikulu cha pathologies - cholesterol ndipo imathetsa mwachangu.
Malinga ndi malangizo ogwiritsira ntchito, motsutsana ndi zakumwa za mankhwala Aterol, njira zotere zimachitika mthupi:
- Zizindikiro zazikulu za matenda oopsa zimatha - tinnitus, mutu, ntchentche m'maso,
- cholesterol imayamba kuchotsedwa itatha yoyamba mlingo,
- magazi amayenda,
- Mitsempha yamagazi imakhala yowonjezereka, yolimba,
- metabolism imabwezeretseka, kuphatikiza lipid,
- njira kagayidwe kazinthu cell bwino,
- mafuta achotsedwa
- magazi ndi zamitsempha zimatsukidwa (palibe chifukwa chochita njira yotsika mtengo ya plasmapheresis).
Kuphatikiza apo, mawonekedwe achilengedwe amalola kuti azigwiritsidwa ntchito ndi anthu pafupifupi onse. Malangizo ogwiritsira ntchito akuti palibe contraindication, kupatula pa tsankho la munthu payekha. Ubwino wina ndikuti mutha kugula osagwiritsa ntchito mankhwala. Madokotala amalimbikitsa kumwa mankhwalawa kupewa matenda a mtima.
Zizindikiro ziti zomwe zikusonyeza kuti munthu ayenera kugula mankhwala olembetsera matenda oopsa:
- chizungulire
- kufooka, kuthamanga kwamtima,
- thukuta kwambiri, makamaka usiku,
- redness kumaso
- cholakwika mu akachisi,
- kumva pafupipafupi kuzizira
- nkhawa
- kusokonezeka kwa kukumbukira
- kuchepa kwa magwiridwe
- ntchentche pamaso panu
- Kutupa kwam'mawa m'mawa,
- dzanzi la miyendo
- mafupa akuda achikuda pansi pa khungu,
- kupweteka ndi kufooka m'miyendo mukuchita masewera olimbitsa thupi.
Mankhwala amalimbikitsidwa osati pokhapokha ngati ali ndi ziwonetserozi pamwambapa, komanso ngati anthu ali pachiwopsezo:
- Tsiku lililonse timapanikizika.
- Kusuta.
- Mowa
- Zakudya zopanda pake.
- Kulemera kwambiri.
- Kudziletsa.
- Khalidwe labwino.
- Kugwiritsa ntchito mankhwala kwa nthawi yayitali (ma immunosuppressants, mahomoni).
Zigawo zapadera
Aterol ili ndi zinthu monga Yerusalemu artichoke Tingafinye, ma potiotiki, CHIKWANGWANI chamafuta chotchedwa fibregam:
- Yerusalemu artichoke Tingafinye. Chifukwa cha zinthu zingapo zomwe zimapanga Yerusalemu artichoke, thupi limakhala ndi zotsatirapo zabwino. Inulin ndi yothandiza kwa anthu odwala matenda ashuga. Kuphatikiza apo, chinthuchi chimachotsa poizoni m'thupi, kuphatikiza cholesterol. Kutulutsa kwa Yerusalemu artichoke kumapangitsa kuti thupi lizigonjetsedwa ndi matenda angapo komanso ma virus. Imagwira ngati chosangalatsa chowonjezera magazi. Ili ndi zida zotsutsa-kutupa.
- Kuphatikizika kwa ma protein. Izi zimathandizira kukulitsa chitetezo champhamvu. Chotsani poizoni, zopangidwa ndi zinthu zovulaza. Amayeretsa magazi ku cholesterol, ma lymph ku mankhwala oopsa. Zithandizirani pakuchepa kwamphamvu kwamafuta. Sinthani microflora ya m'mimba, kupewa matenda oyambitsidwa ndi cholesterol komanso shuga.
- CHIKWANGWANI chamacacia. Ndizofunikira kuti mtima ugwire ntchito, kutsitsa cholesterol m'magazi, ndikuthandizanso kutulutsa kwamisempha (kumasuka kwa makoma) ngati magazi atatha. Amathandizira kuchotsedwa kwa matenda oyipa ndi tizilombo tina tating'onoting'ono. Amathandizira chiwindi, lipid metabolism imayenda bwino.
Pazovuta, zinthu zomwe zimaphatikizidwa ndikupanga zimapangitsa kuti kagayidwe kazachilengedwe kazitsekere, kutseka ndikupanga matenda opatsirana tizilomboti. Siyani kuwola. Mothandizidwa ndi mankhwalawa, kuphatikiza kwama mahormoni kumasintha, ntchito ya ziwalo zam'mimba m'mimba (thirakiti la m'mimba) imathandizira, mankhwala owopsa amawonongeka ndikuthiridwa.
Aterol ndi mankhwala omwe amayambitsa njira zoyenera za metabolic, motsutsana ndi maziko obwezeretsa microflora yopindulitsa.
Kuti muwone kugwiritsidwa ntchito bwino kwa mankhwalawa, mutha kuyendera pazokambirana ndikuwerenga ndemanga. Zomwe zimapanga zotsutsana, mutha kufunsa dokotala. Koma malangizo ogwiritsira ntchito ali ndi chidziwitso choti palibe contraindication. Zilibe zovuta. Palibe chizolowezi ngakhale mutagwiritsidwa ntchito kwa nthawi yayitali.
Kodi ndizotheka kuchepetsa thupi?
Aterol ndi mankhwala omwe samathandiza kokha ndi matenda oopsa. Ndi iyo, mutha kuchepetsa thupi. Kulemera mopitirira muyeso kumayambitsa zifukwa ziwiri - kuperewera kwa vuto la kuperewera kwa zakudya m'thupi komanso ma pathologies ena (makamaka okhudzana ndi kuphwanya njira za endocrine). Poyerekeza ndi izi, chiwindi chilibe nthawi yopanga ma enzyme okwanira kupangira poizoni. Zotsatira zake, zimakhala mthupi ndipo zimayenda bwino pamatumbo, m'magazi ndi m'mimba. Matumbo a m'matumbo "otsekeka" ndi poizoni ndi slag amakhala chifukwa cha kuchuluka kwa mafuta m'thupi. Zotsatira zake, munthu amayamba kunenepa.
Popeza ndaphunzira kapangidwe ka Aterol, sizovuta kudziwa kuti pambuyo pa makonzedwe, kuyeretsa kwambiri kwa thupi kumayamba osati kokha ku cholesterol, komanso kuchokera ku poizoni wam'mimba. Kuphatikiza apo, ntchito ya chiwindi imakhala yofanana.
Zotsatira zophatikizika za zigawo za mankhwala zimapangitsa thupi kugwira ntchito mwanjira yatsopano, monga wotchi. Kulemera kumachepetsedwa mwachangu, koma sikuvulaza ndikusautsa thupi.
Ndemanga za mankhwala
Kodi omwe amagwiritsa ntchito amalemba chiyani za mankhwalawa.
Elena Anatolyevna, wazaka 37, Moscow
Kulikonse komwe ndidapitako, ndidangowerenga ndemanga zabwino za mankhwalawo. Mtengo wa mankhwala othandizira matenda oopsa umakhala wotsika mtengo, ndipo kapangidwe kake kanandikhutiritsa. Ndinaganiza zoyeserera mankhwalawo. Zowonadi, kuchepa thupi kudali kuoneka kale patsiku lachitatu. Adayamba kumva bwino, ntchentche m'maso mwake. Wopanga adapanga chida chabwino kwambiri ndikumuthokoza chifukwa cha izi.
Alexander Stepanovich, wazaka 56, Chita
Adotolo adandilangiza dotolo wanga. Mwana wanga wamwamuna adapeza forum pomwe timawerenga osati malangizo okha ogwiritsira ntchito, komanso ndemanga za anthu. Ngakhale ndimakhala wokayikira pazida za pa intaneti, mwana wanga wamwamuna adanenanso kuti ndiyese mapiritsi. Ndidakonda chidacho. Ndikufuna kuyitanitsanso. Ndimamva bwino.
Julia, wazaka 43, Moscow
Nthawi zonse ndimatsatira chithunzi, koma m'zaka zaposachedwa zakhala zovuta kuchita izi. Kuphatikiza apo, zakudya zomwe zimadya zimatha kuvulaza thupi. Ntchito yayikulu pakuchepetsa thupi ndikuyeretsa matumbo, magazi ndi zamitsempha. Ndinafunsa dotolo. Anaphunzira malangizo omwe angagwiritsidwe ntchito, kapangidwe kake ka mankhwalawo ndikulimbikitsa kwa ine.
Zingachitike, ndinapita kumsonkhanowu, ndinawerenga ndemanga ndipo ndinasankha kuyitanitsa. Zotsatira zake ndizokhutitsidwa kwambiri. M'masabata awiri ndinataya 7 kg! Ndikulangira aliyense amene akufuna kuchepetsa thupi.
Anna Vasilievna, wazaka 58, St. Petersburg
Mwamuna wanga ndi ine timakonda kanyenya komanso nkhokwe zopangidwa tokha. Pazaka zathu, zakudya zophika kale zimakhala zovulaza. Koma sitingathe kudzikaniza tokha kusangalala ndi kaphikidwe kabwino. Mwangozi ndidakumana ndi chidziwitso pa Atherol patsamba lina. Kuphatikizikako ndikwachilengedwe, palibe contraindication, ndipo koposa zonse, mtengo ndiolandiridwa. Tidakonda chidacho. Timadziona kuti ndife ochepera zaka 10.
Sergey Valerievich, wazaka 59, mtima wazamtundu wapamwamba kwambiri
Mankhwalawa ndi othandizadi ku mavuto omwe ali ndi matenda oopsa. Zinthu zomwe zimapanga zomwe zimapangidwa zimachotsa mwachangu ma cholesterol, chotsani poizoni. Ndipo izi zimatsimikiziridwa osati kokha ndi maphunziro omwe ndidadziwana nawo ndekha, komanso ndi zokumana nazo zanga. Ndikumamwa makapisozi, odwala anga amamva bwino, zizindikiro za matenda oopsa siziwawa. Ine, monga dotolo wapamwamba kwambiri, ndimalimbikitsa mankhwalawa kwa aliyense! Koma musanagwiritse ntchito, muyenera kufunsa katswiri. Sitikulimbikitsidwa kuti mutenge makapisozi pokhapokha ngati thupi lanu siligwirizana. Nthawi zina, mankhwalawo amakhala otetezeka komanso osavulaza.
Kodi mankhwala ochepetsa magazi m'thupi ndi ati
Cholesterol ndi chinthu chama protein chomwe chimapangidwa ndi chiwindi. Ichi chimagwiritsidwa ntchito kupanga minyewa yaubongo, mitundu ina ya mahomoni: testosterone, estrogen.
Kuwonjezeka kwa kuchuluka kwa mapuloteni m'magazi kumawonetsa kuti chiwindi chimasokonezeka. Kuphukira kwa bile ducts kumathandizira kuti izi zitheke. Mu thupi lathanzi, gawo lomwe limalowa m'chiwindi ndi chakudya limasinthidwa kukhala bile acid. Amalowetsedwa ndulu, kenako amalowetsa duodenum, amatengako chimbudzi ndipo amatulutsidwa m'thupi ndi chakudya chotsala.
Pamene bile duct obstruction ikachitika, cholesterol imayenda mu ziwiya. Chifukwa cha izi, atherosranceotic plaques form. Amawonjezera magazi, kutseka mipata m'matumbo. Izi zimayambitsa matenda a coronary, malo otayirira angayambitse matenda a mtima.
Kanema wambiri komanso wofunikira kwambiri pankhani ya cholesterol
Pafupifupi 70% ya cholesterol yonse imapangidwa ndi thupi lokha. Gawo limodzi mwa magawo atatu a chinthucho limabwera ndi chakudya. Popanda izi, thupi la munthu silingathe kugwira ntchito.
Zomwe mankhwala amachepetsa
Kugawidwa kwa mankhwala omwe amachepetsa mulingo wake m'magazi kumadalira momwe amapangira. Imachitika motere:
Mankhwala omwe amalepheretsa kaphatikizidwe ka cholesterol "yoyipa":
Khalani omasuka kufunsa mafunso anu kwa wazachipatala wa nthawi zonse mwachindunji patsamba lino. Tikuyankha motsimikiza: Funsani funso >>
Owerenga athu adagwiritsa ntchito bwino Aterol kutsitsa cholesterol. Kuwona kutchuka kwa malonda, tidaganiza zoperekera chidwi chanu.
- Statin - ndi amodzi mwa mankhwala othandiza kwambiri kuchepetsa lipid. Amatchinga ma enzymere opanga cholesterol. Nthawi yomweyo, kuchuluka kwa cholesterol “yoyipa” m'magazi kumachepera. Ma Static ndi otetezeka, koma ndizoletsedwa kupitirira muyeso. Amalembedwa kuti azigwiritsidwa ntchito madzulo (kamodzi patsiku), chifukwa cholesterol imadzuka kwambiri momwe mungathere usiku. Ma Statin amapatsidwa matenda a endocrine gland kuphatikizapo shuga. Sizimakhudza kagayidwe kazakudya. Mphamvu ya kutenga ma statins imawonekera patatha masiku angapo, zotsatira zake zimakhala zowonekera patatha mwezi umodzi. Madokotala ndi odwala amasiya malingaliro abwino okhudza gulu ili la mankhwalawa.
- Ziphuphu ndi mankhwala omwe amachepetsa kuchuluka kwa triglycerides m'magazi. Pochepera, amachepetsa kuchuluka kwa cholesterol. Amagwiritsidwa ntchito pa hypertriglyceridemia yofunika.
- Probucol ndi mankhwala omwe amathandizira kuchepetsa cholesterol ya mitundu yonse iwiri (yabwino ndi yoyipa). Mankhwala samakhudza kuchuluka kwa triglycerides. Studucol imakulitsa kuchuluka kwa mapuloteni omwe amapanga limodzi ndi bile kuchokera mthupi. Zotsatira zake zitha kuwonekera patatha miyezi iwiri kuchokera pachiwonetsero cha mabungwe.
- Nicotinic acid - mankhwalawa ndi mavitamini a B, omwe amathandizira kuchepetsa "cholesterol" yoyipa ". Mankhwalawa amachepetsa kwambiri mphamvu ya magazi kupanga ziwalo zamagazi. Kuchiza ndi mankhwalawa kumachitika nthawi yayitali. Pang'onopang'ono, ndikofunikira kuwonjezera kuchuluka. Musanagwiritse ntchito nicotinic acid, zakumwa zotentha siziyenera kumwa.
Mankhwala omwe amachedwetsa kuyamwa kwa mapuloteni "oyipa" m'matumbo:
- Mankhwala omwe amachepetsa kuyamwa kwa cholesterol m'matumbo - mankhwalawa amachedwetsa kuyamwa kwa chinthu cha protein panthawi ya chimbudzi ndikuchotsa chakudya m'thupi, kuchepetsa kuchepa kwake m'magazi. Amathandizira kuchotsedwa kwa bile acid, kupondereza chilakolako cha chakudya, chomwe chimapatsa kuchepa kwa thupi. Mankhwala omwe amapezeka kwambiri ndi giya.
- Sequestrant of bile acids - mankhwalawa amamanga bile acid ndipo pang'onopang'ono amawachotsa. Thupi limamva kusowa kwa bile acid, chifukwa chomwe chiwindi chimayamba kupanga cholesterol yabwino. Otsatira mwanjira iliyonse sakhudza kuchuluka kwa triglycerides m'magazi.
Mankhwala ena otsitsa lipid ndi owongolera omwe amawonjezera cholesterol yabwino. Izi zikuphatikiza:
- Essentiale ndi mankhwala omwe amathandizira kuthana ndi cholesterol "yoyipa", imayambitsa mphamvu ya cholesterol yabwino.
- Benzaflavin ndi mankhwala omwe ali m'gulu la mavitamini B12. Mankhwalawa amathandizidwa ndi maphunziro ambiri olandiridwa.
Gome la mankhwala osokoneza bongo
| Mayina Mankhwala Osokoneza bongo | Contraindication | Mtengo |
| Wotsogolera | Kuchepetsa kapena kusokoneza kwa m'mimba, |
kudziwa gawo lililonse la mankhwala
kusuntha kwamtima kwakukulu
ambiri zovuta mkhalidwe wodwala
chiwindi kulephera, cholecystitis
bile duct kutsekeka
Mtengo wa mankhwalawa umatha kusiyanasiyana, zimatengera ndondomeko yamitengo yamaunyolo amitundu.
Mankhwala (ma statins, guaram, probucol, ndi zina) sayenera kugwiritsidwa ntchito panthawi yomwe ali ndi pakati komanso mkaka wa m`mawere. Ngati amayi omwe ali ndi maudindo ali ndi mavuto chifukwa cha cholesterol yayikulu, ndiye kufunsa dokotala. Adzasankha chithandizo chofunikira chomwe chingakhale chotetezeka kwa mwana wosabadwayo ndi mayi woyembekezera.
Zithandizo za anthu
Mutha kutsitsa cholesterol posintha njira zina. Koma muyenera kufunsa dokotala.
- Tengani tincture wa calendula katatu patsiku. Mlingo - 30 akutsikira musanadye kwa mwezi umodzi.
- Flaxseed imathandizira kuchepetsa cholesterol yayikulu. Izi zimagulitsidwa ku pharmacy iliyonse. Flaxseed ikhoza kuwonjezeredwa ku chakudya chilichonse chonse kapena pansi.
- Tengani mizu ya dandelion, musanakupera kukhala ufa. Mlingo - supuni imodzi yamizu musanadye chilichonse. Tengani ufa mpaka kumva bwino.
Zakudya kuti muchepetse cholesterol yayikulu
Pali zakudya zapadera zomwe zimathandizira kuchepetsa kuchuluka kwa mapuloteni m'magazi. Zokonda ziyenera kuperekedwa ku zinthu zotsatirazi: nsomba, nyama yochepa-mafuta (nkhuku, nkhuku, kalulu), buledi wa tirigu wathunthu, masamba abwino ndi zipatso, mafuta a polyunsaturated, mafuta ochepa amkaka, chimanga.
Kanema wokhudza kuchepetsa mafuta a cholesterol
Mukaphika, tikulimbikitsidwa kugwiritsa ntchito njira yofikira, yopukusa kapena kuphika.
Zinthu zomwe zimathandizira kukweza mafuta m'thupi:
- nyama yamafuta (nkhumba),
- mazira
- mafuta odzaza
- kuphika
- mbalame - abakha, atsekwe,
- chakudya chofulumira.
Zochita zolimbitsa thupi zimathandizira kutsika kwamlingo. Mlingo wake wamagazi umatengera zaka komanso jenda.
Ndipo pomaliza, kanema wina wokhudza kuchepetsa cholesterol yopanda mankhwala
Pofuna kupewa matenda osiyanasiyana, tikulimbikitsidwa kuyezetsa magazi a biochemical kamodzi pa chaka kuti muwone zomwe zimachitika m'thupi lonse.
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Malinga ndi wolemba bukuli, kutha kwa mankhwalawa kwa odwala omwe ali ndi matenda amtundu woyamba 1 ndikotheka, funso lokha ndi nthawi yanthawi yamankhwala komanso njira yodziwira payekha (chidziwitso cha sukari.com). ... -
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