Katemera wa matenda a shuga 1
Magazi ochulukirapo ndimavuto omwe anthu ena amakhala nawo. Madokotala akuyesera kuti apeze china chatsopano pochiza matenda ashuga kuti moyo ukhale wosavuta kwa odwala ndikuthandizira kuchira. Matendawa monga matenda am'mimba 1 a shuga asachiritsike ndipo amafuna kuti munthu aliyense azisankha mankhwalawo komanso mankhwala ena.
ZOFUNIKA KUDZIWA! Ngakhale odwala matenda ashuga kwambiri amatha kuchiritsidwa kunyumba, popanda opaleshoni kapena zipatala. Ingowerenga zomwe Marina Vladimirovna akunena. werengani zonena zake.
Zizindikiro ndi zomwe zimayambitsa matenda ashuga
Pali mitundu iwiri yamatenda:
Shuga amachepetsedwa nthawi yomweyo! Matenda a shuga m'kupita kwa nthawi angayambitse matenda ambiri, monga mavuto amawonedwe, khungu ndi tsitsi, zilonda zam'mimba, zilonda zam'mimba komanso matenda otupa! Anthu amaphunzitsa zinzake zowawa kuti azisintha shuga. werengani.
- mtundu woyamba (umabuka ngati pali chibadwa cha njira yolowera m'malo mwatsopano),
- mtundu wachiwiri (wokhala ndi chibadwa, mnjira yayikulu).
Kuphatikiza pa zolephera za cholowa, pali zinthu zina zomwe zikuyambitsa matenda a shuga a 2:
- antibodies a m'magazi,
- kagayidwe kachakudya matenda
- kunenepa
- atherosulinosis
- matenda a mtima
- ovary polycystic,
- ukalamba
- zopsinjika pafupipafupi
- moyo wamakhalidwe.
Zizindikiro za matendawa sizimawoneka nthawi yomweyo, ndipo nthawi zambiri vuto limatha kupezeka pokhapokha ngati magazi akuyeserera. Komabe, kukhalapo kwa zizindikiro zotsatirazi, ndikofunikira kuchita zonse zofunika. Izi zikuphatikiza:
Asayansi atsimikizira kuti anthu amtundu wa Caucasus ndiwomwe angakhudzidwe padziko lonse lapansi.
Mankhwala opatsa chidwi
Njira zatsopano zothandizira odwala matenda ashuga ndi zina mwazinthu zachipatala zomwe zimapangidwa kwambiri. Zatsopano zomwe zimachitika kwa odwala matenda ashuga zimatha kukhala njira yabwino komanso njira yochotsera vutoli mwachangu popanda chofufuza. Osati maukadaulo onse awa omwe amawonedwa mozama, ndipo ena amawonedwa ngati osachita. Komabe, musasokoneze mankhwala aposachedwa kapena katemera, omwe angagwiritsidwe ntchito pochiza matenda a shuga 2, ndi mankhwala ena.
Mankhwala amakono
Chithandizo cha matenda ashuga sichingachitike popanda kugwiritsa ntchito mankhwala. Mankhwala amapereka mitundu yambiri ya mankhwala, koma si onse omwe amatha kuthetsa zomwe zimayambitsa matenda ashuga, ndipo kuti mankhwalawo akhale othandiza, ndikofunikira kuthetsa zomwe zimayambitsa. Kufufuza zamankhwala aposachedwa kumadalira kuphatikiza kwa mankhwala omwe amadziwika kale. Njira yamakono yothandizira mankhwalawa pochizira matenda amtundu wa 1 kapena 2 amachitika mu magawo atatu:
- kugwiritsidwa ntchito kwa "Metformin" kapena "Dimethylbiguanide", komwe kumachepetsa shuga la magazi ndikuwonjezera chidwi cha minofu pazinthu,
- kugwiritsa ntchito mitundu yomweyo ya mankhwala ochepetsa shuga,
- ngati palibe kusintha komwe kumachitika, mankhwala a insulin amachitika.
Maselo a tsinde
Njira zatsopano zochizira matenda amitundu yachiwiri zimaphatikizapo kugwiritsidwa ntchito kwa "zida" zomwe zapangitsa kuti sayansi ipangike. Pakadali pano, chithandizo chamankhwala amtunduwu wa shuga sichitha kulikonse. Pakadali pano, ukadaulo uwu ukuyesedwa kuzipatala ku USA, Germany ndi Israel. Kwa nthawi yoyamba, ophunzira a Harvard omwe adapanga njira yopanga maselo a B ndikuwakweza m'malo opanga zinthu atazindikira kuti ali ndi mwayi wogwiritsa ntchito maselo am'mimba pochiza.
Kuthira mafuta omwe sichoncho?
Njira ina yosachiritsika yochizira “matenda otsekemera” ndi kufalikira kwa mafuta a bulauni. Ichi ndi chimodzi mwazomwe minofu yomwe nyama ndi ana akhanda amakhala nazo khosi la impso, masamba ndi kumbuyo. Kuika chinthu ichi kumatha kuchepetsa kufunika kwa insulini, kusintha kagayidwe ka chakudya chifukwa cha kuchuluka kwa mamolekyulu am'magazi a lipid maselo a bulauni a adipose minofu. Komabe, pakadali pano, njirazi zimawonedwa ngati zosafunikira ndipo zimafunikira kafukufuku wina.
Katemera wamavuto - kuchira ndikotheka
Zatsopano pothandizira matenda a shuga zimapereka ntchito jakisoni wapadera womwe ungalepheretse chitukuko cha matendawa. Njira yochitira mankhwalawa ndi "kuphunzitsa": mankhwalawa omwe adalowetsedwa amateteza mphamvu ya chitetezo cha mthupi kuwononga ma cell a B ndikusintha pang'ono pang'ono za DNA. Mamolekyulu osinthidwa amasiya njira zotupa, chifukwa chake, matenda ashuga amayamba kupita patsogolo.
Kuchiritsa bongo?
Chithandizo cha matenda ashuga, omwe cholinga chake ndi kukonza mkhalidwe wa wodwalayo, kusintha matenda a shuga komanso kuteteza maselo a B, amatchedwa orthomolecularapy pamankhwala. Njirayi imaphatikizapo kudya kwa mlingo waukulu wa zinthu zapadera, monga ma amino acid a shuga, mavitamini ndi michere yambiri. Zinthu zoterezi ndizofunikira kuti muchiritse bwino matenda ashuga. Amalowa mkati mwa thupi pogwiritsa ntchito mitundu yosiyanasiyana: ufa, kuyimitsidwa, mapiritsi.
Palibe maphunziro omwe amatsimikizira kugwira ntchito kwa njirayi.
Zida zachilendo zamankhwala
Njira ina yothandizira masiku ano matenda ashuga ndikugwiritsa ntchito zida zapadera zomwe zimathandizira kukonza kagayidwe kazinthu komanso kuchepetsa matenda a shuga. Mutha kupeza zida zotere m'magulu ena azachipatala ndikugwiritsa ntchito pokhapokha mukaonana ndi dokotala. Katswiriyo amasankha chida chayekha ndi kudziwa mtundu wa momwe adzagwiritsidwire ntchito.
Magnetoturbotron
Pogwiritsa ntchito chipangizo chapadera, ndizotheka kukonza momwe wodwalayo alili: kusintha magwiridwe antchito a metabolic mwa kupangitsa munthu kukhala ndi maginito. Chipangacho chokha chimapangidwa mwa mawonekedwe a kapisozi, okhala ndi ma sensors apadera omwe amayikidwa mkati momwe omwe amatha kulowa mkati mwakuya kwamtundu uliwonse.
Zinthu zina zatsopano
Njira ina yamankhwala yothandizira odwala matenda ashuga ndi inhalers. Zipangizozi zimagwiritsidwa ntchito moyenera ndikuteteza insulin kulowa mthupi. Inhaler ndi yoyenera kwa odwala amitundu 1 ndi 2. Zipangizo zimadutsa gawo lomaliza la kafukufuku ndi kuyesa. Zotsatira zomwe zapezedwa kale zikuwonetsa kukhathamira kwa chipangizochi, bajeti yowerengeka komanso zothandiza pakugwiritsa ntchito.
Kodi zikuwonekabe zosatheka kuchiritsa matenda ashuga?
Poona kuti mukuwerenga izi tsopano, kupambana polimbana ndi shuga wambiri sikuli kumbali yanu.
Ndipo mudaganizapo kale za chithandizo kuchipatala? Ndizomveka, chifukwa matenda ashuga ndi matenda oopsa, omwe, ngati sanapatsidwe, amatha kufa. Udzu wokhazikika, kukodza mwachangu, masomphenya osalala. Zizindikiro zonsezi mumazidziwa nokha.
Koma kodi ndizotheka kuchitira zomwe zimayambitsa m'malo mothandizira? Timalimbikitsa kuwerenga nkhani yokhudza matenda a shuga omwe alipo masiku ano. Werengani nkhani >>
Chithandizo cha katemera wa matenda a shuga 1
Mtundu woyamba wa matenda a shuga a mellitus, malinga ndi zomwe zilipo pakadali pano, ndi matenda a autoimmune pamene ma T-cell awononga ma cell a pancreatic beta. Malingaliro osavuta ndikuchotsa maselo oyera a T. Koma ngati muwononga maselo oyera amthupi, thupi limataya chitetezo ku matenda ndi oncology. Kodi kuthetsa vutoli?
Mankhwala akupangidwa ku America ndi ku Europe komwe kumalepheretsa kuwonongeka kwa maselo a beta ndi chitetezo chathupi. Gawo lomaliza la kuyeserera likuchitika. Mankhwalawa ndi katemera wothandizirana ndi nanotechnology yemwe amakonza zowonongeka zomwe zimayambitsa ma T-cell ndikuyambitsa ma cell ena "abwino" koma ofooka a T. T-cell za Weaker zimatchedwa zabwino, chifukwa sizikuwononga maselo a beta. Katemera ayenera kugwiritsidwa ntchito m'miyezi isanu ndi umodzi mutatha kudziwa mtundu wa matenda ashuga a mtundu woyamba. Katemera akupangidwanso pofuna kupewa matenda ashuga, koma zotsatira zachangu sizoyenera kudikirira. Katemera onse adakali kutali ndi malonda.
Chithandizo cha matenda a shuga 1 amtundu wa extracorporeal hemocorrection
Madokotala a zipatala zambiri zaku Germany samachiza matenda a shuga osati njira zodzisungira zokha, komanso amatembenukira ku thandizo lamakono. Imodzi mwa njira zaposachedwa kwambiri ndi extracorporeal hemocorrection, yomwe imagwira ntchito ngakhale mankhwala a insulin atalephera. Zisonyezo za extracorporeal hemocorrection ndi retinopathy, angiopathy, kuchepa kwamphamvu kwa insulin, matenda a shuga komanso matenda ena okhudzana ndi matenda ashuga.
Chinsinsi cha mankhwalawa a mtundu woyamba wa matenda ashuga ogwiritsira ntchito mankhwala ena am'mimba ndikuchotsa zinthu za m'magazi zomwe zimayambitsa matenda ashuga. Zotsatira zake zimatheka kudzera pakusintha kwa magazi pamagazi kuti asinthe katundu wake. Magazi amapatsirana kudzera mu zida zamafuta zapadera. Kenako imalembetsedwa ndi mavitamini, mankhwala ndi zina zofunikira ndikupita m'magazi. Chithandizo cha matenda ashuga omwe ali ndi extracorporeal hemocorrection zimachitika kunja kwa thupi, kotero chiopsezo cha zovuta zimachepetsedwa.
Mu zipatala za ku Germany, kupukusa plasma kusefera ndi cryoapheresis amatengedwa kuti ndi mitundu yotchuka kwambiri ya magazi amkati. Njirazi zimachitika m'madipatimenti apadera omwe ali ndi zida zamakono.
Chithandizo cha matenda ashuga omwe amaphatikizika ndi kapamba ndi maselo a beta
Opaleshoni ku Germany m'zaka za zana la 21 ali ndi kuthekera kwakukulu ndi luso lalikulu pakugwira ntchito. Odwala omwe ali ndi mtundu woyamba wa matenda a shuga amathandizidwa ndi kupatsirana kwa kapamba konsekonse, minyewa yake, masoka a Langerhans komanso maselo. Ntchito zoterezi zitha kukonza matenda osokoneza bongo komanso kupewa kapena kuchedwetsa zovuta za matenda ashuga.
Kupatsirana kwa kapamba
Ngati mankhwala othandizira kupatsirana amasankhidwa molondola ndi chitetezo cha mthupi, kuchuluka kwa kupulumuka pambuyo pa kupatsirana kwa chamba chonse kumafika 90% pachaka choyamba cha moyo, ndipo wodwalayo angachite popanda insulin kwa zaka 1-2.
Koma opaleshoni yotere imachitika muzovuta kwambiri, popeza chiwopsezo cha zovuta pakuchita opaleshoni chimakhala chambiri nthawi zonse, ndipo kumwa mankhwala omwe amapondereza chitetezo cha mthupi kumabweretsa zotsatira zoyipa. Kuphatikiza apo, pali mwayi wambiri wokanidwa.
Kusamutsidwa kwa mabwalo am'madzi a Langerhans ndi ma cell a beta
M'zaka za m'ma 2000 zino, ntchito yayikulu ikuchitika kuti iphunzire momwe zingasinthidwe magawelo a Langerhans kapena maselo a beta. Madokotala amasamala za kugwiritsa ntchito njirayi, koma zotsatira zake zimakhala zosangalatsa.
Madokotala ndi asayansi aku Germany ali ndi chiyembekezo chamtsogolo. Maphunziro ambiri ali kumapeto ndipo zotsatira zake ndizolimbikitsa. Njira zatsopano zochizira matenda amtundu wa shuga pachaka zimayamba pachaka, ndipo posachedwa odwala amatha kukhala ndi moyo wabwino komanso osadalira insulin.
Zoposa zaka 40 zapitazo, chikhalidwe cha matenda a shuga a mtundu 1 chidadziwika. Asayansi ndi ofufuza padziko lonse lapansi akugwiritsa ntchito katemera wa matenda ashuga amtundu woyamba, omwe angalepheretse kapena kulepheretsa kukula kwa autoimmune reaction motsutsana ndi ma cell a pancreatic beta. Kuyeserera kambiri kwachitika - kuyambira pakugwiritsa ntchito insulin ya mkamwa ndi intranasal, kupita ku ma vaccines a DNA (Mexico vaccine TOL-3021) and autoantibodies osiyanasiyana (anti CD-3). Chimodzi mwa maphunziro aposachedwa adasindikizidwa mu 2017. "Katemera" adayesedwa, omwe ndi ma isoform a recutinate decarboxylase (mankhwalawa Diamide) - imodzi mwazinthu zofunikira kwambiri zomwe zimayambitsa insulin ndi khungu la beta. Pakati pa 2009 mpaka 2012, ana azaka za 4 mpaka 18 zokhala ndi ma antibodies otsimikizika adapatsidwa jakisoni wachiwiri wa katemera ndi masiku 30. Kenako ana adawonedwa kwa zaka 5. Tsoka ilo, mankhwalawa sanachedwe kapena kulepheretsa kukula kwa matenda ashuga amtundu woyamba mwa omwe amayeserera kuyerekeza ndi ana omwe ali pagululi. Koma gulu la asayansi aku Sweden, lotsogozedwa ndi Helena Elding Larsson (Helena Elding Larsson) silitaya mtima ndikukonzekera kafukufuku wowonjezereka pa katemera pogwiritsa ntchito mitundu yamagulu komanso kuphatikiza ndi ma antigen ena.
Ofufuzawo akupitiliza kufufuza njira zatsopano zopewera matenda ashuga amtundu woyamba ndi njira zatsopano zoperekera mankhwala ngati amenewa. Mwachitsanzo, mu Marichi 2019, malingaliro adasindikizidwa ndi asayansi ochokera ku Yunivesite ya Verona kuti aphunzire ma beets ofiira kapena zinthu zina zam'mera zomwe, atasintha masinthidwe amtundu wamtundu, amatulutsa isoantigen glutamate decarboxylase ngati katemera wakumwa kwa matenda ashuga a mtundu woyamba.
Zomwe zafotokozedwazo sindiwo kufunsa kuchipatala ndipo sizingaloze kuyendera dokotala.
Chithandizo chatsopano - mitundu ya katemera wa shuga
Kukula kwambiri komanso kufa kwa anthu kuchokera ku mtundu woyamba wa 2 komanso mtundu wa matenda ashuga 2 kumakakamiza asayansi padziko lonse lapansi kuti apange njira zatsopano ndi malingaliro othandizira matendawa.
Zidzakhala zosangalatsa kuti ambiri aphunzire njira zatsopano zamankhwala, kupanga katemera wa matenda ashuga, zotsatira za zomwe zapezeka mderali.
Chithandizo cha matenda ashuga
Njira zochizira matenda amtundu wa 2 shuga ndizosiyana ndi zomwe zimagwiritsidwa ntchito pochiza matenda amtundu wa shuga.
Zotsatira zamankhwala zomwe zimapezeka pogwiritsa ntchito njira zachikhalidwe zimawonekera patapita nthawi yayitali. Poyesa kuchepetsa kukwaniritsa kwamphamvu pamankhwala, mankhwala amakono akupanga mankhwala ochulukirachulukira, kugwiritsa ntchito njira zatsopano, ndikupeza zotsatira zabwino komanso zabwino.
Pochiza matenda a shuga a 2, magulu atatu a mankhwala amagwiritsidwa ntchito:
- khwawa
- khalimon
- mankhwala a sulfonylurea (m'badwo wa 2).
Zochita za mankhwalawa ndicholinga:
- kuchepa kwa shuga
- kuponderezedwa kwa shuga m'magazi a chiwindi,
- kukondoweza kwa insulin ya insulin pogwiritsira ntchito maselo a pancreatic,
- Kuletsa insulin kukaniza maselo ndi minofu ya thupi,
- kuchuluka insulin kumva mafuta ndi minofu minofu.
Mankhwala ambiri ali ndi zoperewera pakulimbana ndi thupi:
- kunenepa kwambiri, hypoglycemia,
- totupa, pakhungu pakhungu,
- zam'mimba dongosolo.
Chothandiza kwambiri, chodalirika ndi Metformin. Imasinthasintha magwiritsidwe ake. Mutha kuwonjezera mlingo, kuphatikiza ndi ena. Mukamathandizira ndi insulin, ndizovomerezeka kuti musinthe mlingo, kuchepetsa insulin.
Chithandizo chotsimikiziridwa kwambiri cha mtundu 1 ndi matenda a shuga a 2 chinali chithandizo cha insulin.
Kufufuza pano sikuyimilira. Pogwiritsa ntchito zomwe mungagwiritse ntchito pakupanga ma genetic, ma insulin osinthika amtundu wautali ndi wautali amalandiridwa.
Odziwika kwambiri ndi Apidra - insulin yochepa ndi Lantus - woleza mtima.
Kugwiritsa ntchito kwawo pamodzi monga momwe angathere kumathandizira kubisalira kwachilengedwe kwa insulin yopangidwa ndi kapamba, ndipo kumalepheretsa zovuta.
Makina owonera magazi amakompyuta omwe adapangidwa ndi S. Levitiko amawongolera kapamba.Tsamba lokonzekera limapangidwa pambuyo pofotokoza za chipangizo chamagetsi, chomwe wodwalayo amavala masiku 5.
Kuti akhalebe wodekha pakuchiza odwala omwe ali ndi matenda a shuga 1, adapanganso zida zomwe zimamangiriridwa ndi lamba.
Nthawi zonse amasankha shuga wamagazi ndipo, pogwiritsa ntchito pampu yapadera, amalandira jakisoni wodziwika yekha wa insulin.
Zithandizo Zatsopano
Njira zatsopano zopangira matenda ashuga zimaphatikizapo:
- ntchito maselo
- katemera
- kufoola magazi,
- kufalikira kwa kapamba kapena ziwalo zake.
Kugwiritsa ntchito maselo a tsinde ndi njira ya ultramodern. Zimachitika m'makliniki apadera, mwachitsanzo, ku Germany.
Mu labotale, maselo a stem amakula omwe amabzalidwa wodwala. Zotengera zatsopano, minofu imapangidwa mwa iye, ntchito zimabwezeretseka, mulingo wa glucose imasinthidwa.
Katemera wakhala wolimbikitsa. Kwa pafupifupi theka la zaka, asayansi ku Europe ndi America akhala akugwira ntchito ya katemera wa matenda ashuga.
Makina a autoimmune njira mu shuga mellitus amachepetsa kuwonongeka kwa beta maselo a T-lymphocyte.
Katemerayu, wopangidwa pogwiritsa ntchito nanotechnology, ayenera kuteteza maselo a kancreatic pancreatic beta, ndikubwezeretsa malo owonongeka ndikulimbitsa T-lymphocyte zomwe zikusungidwa, chifukwa popanda iwo thupi limakhalabe langozi yotenga matenda ndi oncology.
Kuchepetsa magazi kusefedwa kapena extracorporeal hemocorrection amagwiritsidwa ntchito chifukwa cha zovuta matenda a shuga.
Mwazi umapakidwa kudzera pazosefera zapadera, zolemeretsedwa ndi mankhwala ofunikira, mavitamini. Amasinthidwa, kumasulidwa ku zinthu zapoizoni zomwe zimakhudza ziwiya zamkati.
M'makliniki otsogola padziko lonse lapansi, m'malo opanda chiyembekezo kwambiri omwe ali ndi zovuta kwambiri, kupatsirana chiwalo kapena ziwalo zake ntchito. Zotsatirazi zimatengera wothandizila yemwe sanasankhe bwino.
Kanema wokhudza matenda a shuga ochokera kwa Dr. Komarovsky:
Zotsatira Zazachipatala
Malinga ndi kuchuluka kwa chaka cha 2013, asayansi achi Dutch ndi aku America adapanga katemera wa BHT-3021 pokana matenda ashuga amtundu 1.
Kuchita kwa katemera ndikusintha ma cell a beta, kaphatikizidwe m'malo mwake kuti awonongeke a T-lymphocyte of immune immune.
Maselo opulumutsidwa a beta angayambenso kupanga insulin.
Asayansi amati katemera uyu ndi “katemera wa kusintha zinthu” kapena kusinthiratu. Iyo, yoletsa chitetezo cha mthupi (T-lymphocyte), imabwezeretsa katulutsidwe ka insulin (maselo a beta). Nthawi zambiri katemera aliyense amalimbitsa chitetezo cha mthupi - kuchitapo kanthu mwachindunji.
Dr. Lawrence Steiman wa ku yunivesite ya Stanford adatcha katemerayu "katemera woyamba wa dziko lapansi ku dziko lapansi," chifukwa, monga katemera wofanana ndi chimfine, samatulutsa chitetezo mthupi. Amachepetsa ntchito ya maselo oteteza kumatenda omwe amawononga insulin popanda kukhudza mbali zake zina.
Katemera woyeserera anayesedwa pa anthu 80 odzipereka.
Kafukufuku wasonyeza zotsatira zabwino. Palibe mavuto omwe adapezeka. Maphunziro onse anali ndi kuchuluka kwa C-peptides, zomwe zikuwonetsa kubwezeretsa kapamba.
Kuti mupitilize kuyesa, chilolezo cha katemera chinasamutsidwa ku Tolerion, kampani yopanga biotechnology ku California.
Mu 2016, dziko lidaphunzira za malingaliro atsopano. Pamsonkhanowu, Purezidenti wa Mexico Association for Diagnosis and Treatment of Autoimmune matenda, a Lucia Zarate Ortega, ndi Purezidenti wa Victory Over Diabetes Foundation, a Salvador Chacon Ramirez, adapereka mtundu watsopano wa 1 ndi mtundu wa 2 wa katemera wa matenda ashuga.
Maluso a katemera wa katemera ali motere:
- Wodwala amalandira ma 5 a magazi kuchokera m'mitsempha.
- 55 ml ya madzi apadera ophatikizidwa ndi saline yachilengedwe amawonjezeredwa ku chubu choyesera ndi magazi.
- Zosakanikirana zotumizirazo zimatumizidwa mufiriji ndikusungidwa pamenepo mpaka osakaniza atazizira mpaka madigiri 5 Celsius.
- Kenako kutentha kutentha kwa thupi la madigiri 37.
Kusintha kwa kutentha, kapangidwe kake ka osakaniza kamasinthika mwachangu. Zotsatira zomwe zidzapangidwe ndizoyenera kukhala katemera waku Mexico. Mutha kusunga katemera wotere kwa miyezi iwiri. Chithandizo chake, komanso zakudya zapadera komanso masewera olimbitsa thupi zimatha chaka.
Asanalandire chithandizo, odwala amapemphedwa nthawi yomweyo, ku Mexico, kukayezetsa.
Kupambana kwa maphunziro aku Mexico kwatsimikiziridwa padziko lonse lapansi. Izi zikutanthauza kuti katemera waku Mexico walandila "tikiti ya kumoyo."
Kufunika kwa kupewa
Popeza njira zatsopano zamankhwala sizipezeka kwa aliyense yemwe ali ndi matenda ashuga, kupewa matendawa ndi vuto lalikulu, chifukwa matenda amtundu wa 2 ndi matenda omwewo, kuthekera kwa kudwala komwe kumatengera munthu yemwe.
Malangizo zodzitchinjiriza ndi malamulo a moyo wabwino:
- Zakudya zoyenera komanso chikhalidwe.
- Maluso akumwa madzi.
- Moyo wapaulendo, wogwira ntchito.
- Kuchotsera mitsempha yambiri.
- Kukana zizolowezi zoipa.
- Kuwongolera matenda omwe alipo.
- Kuchiritsa mpaka kutha kwa matenda opatsirana, osakhazikika.
- Onani kupezeka kwa helminths, mabakiteriya, majeremusi.
- Pogwiritsa ntchito mankhwala kwa nthawi yayitali, mumapereka magazi pafupipafupi kuti muunikidwe.
Zakudya zoyenera ndizofunikira kwambiri kupewa.
Ndikofunikira kuchepetsa zakudya zotsekemera, ufa, mafuta ochulukirapo. Pewani zakumwa zoledzeretsa, koloko, zakudya zachangu, zakudya zachangu komanso zosafunikira, zomwe zimaphatikizapo zinthu zovulaza, zoteteza.
Onjezerani zakudya zamitundu yambiri:
Imwani madzi oyeretsedwa mpaka malita awiri masana.
Pamafunika kuzizolowera komanso kuwona masewera olimbitsa thupi ngati zinthu zabwinobwino: kuyenda kwamtali wautali, masewera akunja, kukwera miyendo, kukwera masitima oyendetsa ndege.
Zatsopano pamankhwala a shuga
Kuchita bwino kwa mankhwalawa a "matenda okoma" nthawi zambiri sikukumana ndi zomwe odwala ndi madokotala amayembekeza. Zachidziwikire, pakadali pano pali mankhwala ena abwino ochepetsa kuchuluka kwa shuga m'magazi, koma kufunafuna njira zapamwamba ndi mankhwala ambiri kukupitirirabe.
- Zatsopano mu Type 1 Shuga
- Health Technology
- Zatsopano mu Type 2 Shuga
Asayansi chaka chilichonse amayesetsa kupanga china chatsopano pochiza matenda ashuga kapena kukonza momwe mankhwala alili. Pazaka 10 zapitazi, zida zambiri komanso matekinoloje ena adawoneka kuti mtsogolomo azitha kuyendetsa bwino kwambiri moyo wa odwala ndikupangitsa chithandizo cha matendawa kukhala chothandiza kwambiri.
Zatsopano mu Type 1 Shuga
Vuto lalikulu la "matenda okoma" omwe amadalira insulin ndi kuchuluka kosakwanira kwa mahomoni a pancreatic m'thupi kapena kusakhalapo kwathunthu. Chifukwa chake, madokotala ndi asayansi akuyesera kuti apeze njira zothandizira gawo la parenchyma kuti athandize kukula kwa maselo a B.
Chatsopano pochiza matenda amiseche 1 amaphatikizapo njira zotsatirazi:
- Chithandizo cha matendawa pogwiritsa ntchito maselo a tsinde. Njira imodzi yodalirika mtsogolo, yomwe ingathe kuchiritsa vutoli ndi metabolism ya carbohydrate. Chomwe chimapangidwira chithandizo chatsopano ndikukula kwa maselo a B mu labotore. Zotsogola zamitundu yonse m'thupi la munthu ndizinthu zomwe zimapangidwa, zomwe zimatha kusinthidwa kukhala gawo lililonse lazomwe zimagwira ntchito m'thupi. Asayansi aku Harvard adatha kubereka kwamatenda a B-cell omwe amagwira ntchito mu mbewa ndikuchiritsa kwathunthu nyama chifukwa cha kuperewera kwa insulin. Njirayi imadutsa gawo lina la mayeso athunthu a ma labotale, koma tsopano mabungwe ena azachipatala ku USA, Germany ndi Israel akupatsa odwala awo njira yosinthira chithandizo.
- Posachedwa, kuyesedwa kwakukulu kwachipatala koika anthu odwala "matenda okoma" kwatha. Njira ngati imeneyi imachepetsa kufunikira kwa insulin ndipo imachepetsa kagayidwe kazakudya chifukwa kuphatikizika kwakukulu kwa mamolekyulu a glucose a adipocytes (lipid cell) a inshuwaransi yamafuta a bulauni. Komabe, chithandizo choterechi chimafunikabe kuyesedwa.
- Katemera wa shuga. Katemera wapadera wapangidwa "yemwe amaphunzitsa" chitetezo chake mthupi kuti chisawononge ma cell a pancreatic B. Molekyu ya DNA yosinthika imalepheretsa kutuluka kwa chiwalo ndikuletsa kukula kwa matendawo.
Health Technology
Ngati tikunena za chinthu chatsopano pochiza matenda amtundu 1, ndiye chifukwa chake tiyenera kunena za zida zotsatirazi:
- Net Science Science Glycemic Laser Sensor. Pakangogwira ntchito masekondi 30, imazindikira kuchuluka kwa shuga mu seramu popanda kumenya chala komanso kumwa magazi. Kutengera njira yowunikira chizindikiro cha fluorescence.
- Chida chothandizira kupuma kwa glucagon. Zimapangitsa kuyendetsa mahomoni kudzera m'mphuno momasuka komanso kumapereka mlingo wokwanira wa mankhwalawo. Mtengo wa chipangizocho ndi zovomerezeka, zomwe zimapangitsa kuti akhale otchipa kwa odwala osiyanasiyana. Chida choterocho chikuyamba kutchuka ku West ndi USA.
- Kuthandiza odwala matenda ashuga ndi njira zatsopano kumaphatikizapo kugwiritsa ntchito mitundu yapamwamba kwambiri ya instopu ya insulin. Njira yothandizidwa ndi mankhwalawa pamagawo aliwonse amtundu wachilendo. Komabe, umunthu umazolowera kale. Kusintha kwakukulu kwa zida zamakono ndi:
- Clogging Prevention System
- Kudzikongoletsa ndi singano ya kudziziritsa nokha ndi chitetezo chowonjezera ndi kapangidwe kapadera,
- Kuthekera kolumikizira kachitidwe mu malo osiyanasiyana 8 kwa chitonthozo chachikulu cha odwala,
- Kukhalapo kwa magwiridwe antchito ambiri. Wodwala amatha kusintha pompopompo moganizira zonse zomwe zimathandizira, zomwe zimapangitsa kuti pakhale chithandizo chokwanira.
Zatsopano mu Type 2 Shuga
Cholinga chachikulu chimakhala kufunafuna mankhwala othandiza kwambiri kuti athane ndi insulin.
Zatsopano pa mankhwalawa matenda a shuga a 2 amaphatikizira:
- Kugwiritsa ntchito zida za "Magnetoturbotron". Zimawonjezera kuchuluka kwa mpweya mu seramu ndipo zimakhudza kagayidwe kazakudya ka wodwala. Pali kuchepa kwa hyperglycemia.
- Kugwiritsa ntchito mankhwala a cryosauna ndi laser kumawonjezera chiwopsezo cha minyewa chifukwa cha mphamvu ya ma pancreatic.
- Mankhwala atsopano a shuga ayamba kutchuka. Izi zikuphatikiza:
- Glucagon-ngati peptide agonists (GLP-1). Chepetsani kulemera kwa wodwala. Amawongolera mafuta kagayidwe ndipo amachepetsa kukana kwa thupi pazotsatira za insulin.
- Zoletsa za dipeptidyl peptidase-4 (DPP-4). Onjezani kaphatikizidwe kakang'ono ka ma insretins, omwe amathandizira kuwonjezeka kwa kupanga kwa amkati pancreatic timadzi popanda kutaya.
- Njira yomwe idakhazikitsidwa ndi kukakamiza kwa vasoloma endothelial grow factor VEGF-B. Kulepheretsa kudutsa kwa ma cell kumitsempha ndi m'mitsempha kupita ku ubongo, komwe kumalepheretsa kuchuluka kwa lipids mu minofu ya mtima ndi minofu. Chifukwa chake, "kuyankha bwino" kwamitunduyi ku insulin kumasungidwa. Ichi ndichinthu chatsopano kwambiri pochiza matenda a shuga a mtundu wachiwiri, omwe sanaganizidwepo zaka zingapo zapitazo.
Sayansi ndi mankhwala sizimayima. Tsiku lililonse, asayansi padziko lonse lapansi akuyesera kupeza zosankha zingapo zamomwe angapulumutsire anthu ku "matenda okoma." Pakadali pano, palibe mankhwala omwe angathane ndi vutoli kwathunthu, koma matekinoloje aposachedwa pothana ndi matenda a shuga amawoneka opatsa chiyembekezo.
Chithandizo cha matenda a shuga 1
Matenda a shuga amatchedwa pathology, omwe amadziwika ndi vuto la metabolic, lomwe ma polysaccharides omwe amalowa mthupi samamwa bwino, ndipo kuwonjezeka kwa shuga m'magazi kumafika pazovuta zambiri. Mitundu yotsatirayi ya matendawa ilipo: wodalira insulin (mtundu 1), wosadalira insulini (mtundu 2). Chithandizo cha mitundu yonse ya "matenda okoma" ndizosiyana. Njira zakuchizira ndizovuta komanso zingapo. Chithandizo cha matenda a shuga 1 amitundu yodziwika bwino ndi wowerengeka amatchulidwa munkhaniyi.
Zolemba za matendawa
Mtundu wa "matenda okoma" omwe amadalira insulin amakula pafupipafupi ubwana kapena unyamata. Njira ya pathological imadziwika ndi insulin yokwanira ya pancreatic hormone insulin, chifukwa chomwe thupi limalephera kugwiritsa ntchito shuga. Ziwalo sizilandira mphamvu zokwanira, chifukwa chomwe zimagwira.
Chifukwa chachikulu chakukhazikitsidwa kwa mtundu woyamba wa matenda ashuga ndi vuto lakabadwa. Komabe, chimodzi mwazomwe zimayambitsa matendawa sikokwanira. Monga lamulo, matenda a ma virus ndi kuwonongeka kwa kapamba amatenga gawo lalikulu, zimapangitsa kuwonongeka kwa insulin mobisa maselo a chiwalo.
Magawo otsatirawa a mtundu wa "matenda okoma" omwe amadalira insulin alipo:
- zam'tsogolo zamatendawa,
- kuwonongeka kwa maselo ndi zinthu zingapo zopangitsa kukhazikitsa kusintha kwa masinthidwe amthupi ndi thupi,
- gawo la yogwira autoimmune insulitis - ntchito ya antibody ndiyokwera, kuchuluka kwa ma cell a insulini kumachepetsedwa, mahomoni amapangidwa osakwanira,
- yogwira pophwanya insulin - nthawi zina, wodwalayo amatha kudziwa kuphwanya shuga, kuthamanga kwa shuga wa plasma,
- kutalika kwa matendawa ndi kutuluka kwa chithunzi chowoneka bwino - - 85% yama cell a ma islets a Langerhans-Sobolev a kapamba awonongedwa,
- kuwonongedwa kwathunthu kwa maselo a ziwalo komanso kuchepa kwamphamvu kwa insulin.
Mawonetseredwe akulu am matendawa
Pa matenda amtundu wa 1 wodwala, wodwalayo amadandaula za zotsatirazi: ludzu la m'magazi, kutulutsa mkodzo kwambiri komanso ma membrane owuma. Kulakalaka kwambiri kumachitika limodzi ndi kuwonda kwambiri. Pali kufooka, kuchepa kwa kuwona kwakumaso, kuzungulira kwa pakhungu pakhungu. Odwala amadandaula kuti amakonda kupatsirana matenda apakhungu.
Kupanda thandizo pamlingo wa mawonetsedwe otere kumabweretsa kuti matendawo akupita patsogolo.
Zovuta zopweteka komanso zopweteka zimayamba:
- zilonda zam'mimba za m'munsi,
- kuphwanya chinsinsi cha m'mimba ndi matumbo,
- kuwonongeka kwa zotumphukira zamanjenje,
- kuwonongeka kwa
- matenda a kwamikodzo, makamaka impso,
- matenda a shuga
- kubweza kwakukula kwakuthupi kwa ana.
Mfundo zakuchiritsa matenda
Odwala omwe atsimikiziridwa kuti apezeka ndi matenda omwe amadalira insulin amafunsidwa ndi dokotala wawo ngati mtundu wa 1 wa matenda ashuga ungathe kuchiritsidwa kwamuyaya. Mankhwala amakono sangathetsenso wodwalayo matendawa, komabe, njira zatsopano zamankhwala zimatha kubwezeretsa chindapusa cha matendawa, kuletsa kukula kwa zovuta komanso kukhalabe ndi moyo wabwino wodwala pamlingo wambiri.
Chithandizo cha matenda a shuga 1 amakhala ndi zotsatirazi:
- mankhwala a insulin
- kukonza zakudya,
- zolimbitsa thupi
- physiotherapy
- kuphunzitsa.
Mawonekedwe Amphamvu
Nutritionists ndi endocrinologists amalimbikitsa kuti wodwalayo azitsatira manambala 9. Kutengera ndi matenda omwe amapezeka, kuchuluka kwa thupi la wodwala, jenda, zaka, kupezeka kwa zovuta ndi zisonyezo za glycemia, dokotala wopezekayo amasintha menyu wodwala.
Zakudya nambala 9 zikusonyeza kuti chakudya chimayenera kuperekedwa nthawi zambiri, koma pang'ono. Kuchuluka kwa chakudya chamafuta kumakhala kochepa, makamaka ma polysaccharides (zakudya zamafuta, fiber) amagwiritsidwa ntchito. Izi ndizofunikira popewa kulumpha lakuthwa m'magazi a magazi, koma nthawi yomweyo kuti thupi lilandire zokwanira "zomanga".
Kalori yatsiku ndi tsiku imawerengeredwa payekhapayekha. Kuchuluka kwa mapuloteni muzakudya za tsiku ndi tsiku kumawonjezeka chifukwa cha zinthu zomwe zimachokera kuzomera, ndipo kuchuluka kwa mafuta, m'malo mwake, kumachepa (kudya kwa lipids za nyama ndikochepa). Wodwala ayenera kukana shuga konse. Itha m'malo ndi zotsekemera zachilengedwe (uchi, mapulo manyuchi, stevia Tingafinye) kapena kupanga zina (fructose, xylitol).
Mavitamini ndi michere yokwanira iyenera kubwera, chifukwa amachotsedwa mthupi motsutsana ndi polyuria. Makonda amasankhidwa kuphika, ophika, chakudya chophika, ndi zotupa. Kuchuluka kwa madzi akumwa sayenera kupitirira 1500 ml patsiku, mchere - mpaka 6 g.
Ngati matenda a shuga akuphatikizidwa ndi nthawi ya bere, ndikofunikira kuchepetsa zopatsa mphamvu tsiku ndi tsiku kukhala 1800 kcal. Izi zimachepetsa chiopsezo cha zovuta m'mayi ndi mwana. Madzi ndi mchere wolowera uyeneranso kukhala ochepa kuti muchepetse nkhawa pamiyendo ndikuti mupewe kuchitika kwa matenda amkodzo.
Pazakudya za ana odwala, payenera kukhala zakudya zazing'ono pakati pa chakudya, musanayambe kuchita masewera olimbitsa thupi, masewera olimbitsa thupi osiyanasiyana. Ngati palibe zovuta za matenda oyambitsidwa, kuchuluka kwa zinthu zomangira “kuyenera kuyenerana ndi msinkhu ndi thupi la mwana. Ndikofunikira kuwerengera moyenera mlingo wa insulin, kudziwa pafupifupi chakudya.
Zochita zolimbitsa thupi
Ndizovuta kwambiri kuchiza matenda ashuga amtundu woyamba popanda kuchita masewera olimbitsa thupi mokwanira. Masewera ali ndi zotsatirazi mthupi la wodwalayo:
- zimapangitsa chiwopsezo cha minofu ndi maselo kupita ku mahomoni,
- kumawonjezera mphamvu ya insulin,
- imalepheretsa chitukuko cha matenda a mtima ndi mtsempha wamagazi,
- kubwezeretsa zowonetsa,
- Iyamba Kuthamanga kagayidwe kachakudya njira.
Ogwira ntchito zaumoyo amalimbikitsa kuti asankhe masewera omwe sangakhudze kwambiri zowonera, kwamikodzo, mtima, ndi miyendo. Amaloledwa kuyenda, kulimbitsa thupi, tennis ya tebulo, kusambira, masewera olimbitsa thupi. Ndi matenda a shuga a mtundu woyamba, mutha kuchita masewera olimbitsa thupi osaposa mphindi 40 patsiku.
Ndi kulimbitsa thupi kosalekeza, ndikofunikira kuchepetsa mlingo wa insulin yomwe mumalandira. Izi zidziteteza ku kukula kwa hypoglycemia. Kuphatikiza apo, muyenera kukhala ndi chilichonse chokoma ndi inu. Musanayambe kusewera masewera, muyenera kuyeza shuga wamagazi, ndipo mukamachita masewera olimbitsa thupi muyenera kuyendetsa bwino kugunda kwanu komanso kuthamanga kwa magazi.
Mankhwala a insulin
Kutengera mtundu wa matendawo, mankhwalawa amafunika pafupifupi 40% pamavuto onse azachipatala. Cholinga cha chithandizo chotere ndi motere:
- normalization wa saccharide metabolism (njira yabwino ndiyo kusintha shuga m'magazi ndikutchinjiriza kuwonjezeka kwambiri chakudya chikamalowa m'thupi, mokwanira - kuthetsa mawonetseredwe azachipatala),
- kukhathamiritsa kwa zakudya ndikusunga mayeso oyenera amthupi
- kukonza lipid kagayidwe,
- kukonza moyo wabwino wodwala,
- kupewa mavuto a mtima ndi minyewa chikhalidwe.
Mankhwala othandiza
Pakadali pano, mankhwalawa osankhidwa ndi a insulin yaumunthu yopangidwa kuchokera kumtundu kapena biosynthetic, komanso mitundu yonse ya mankhwala omwe amapezeka pamaziko ake. Mankhwala amakono omwe amaperekedwa ndikulembetsedwa amasiyana m'njira zawo: Mankhwalawa ogwirira ntchito, osakhalitsa komanso osakhalitsa.
Mayankho omwe amachitika mwachidule akuphatikizapo Actrapid NM, Humulin-wokhazikika, Biosulin. Oimira awa amadziwika ndi kukwera msanga kwa zotsatirazo komanso kufupika kwa kuchitapo kanthu. Amaperekedwa mwachangu, koma ngati ndi kotheka, jakisoni wamkati kapena wamkati ndikotheka.
Mankhwala a nthawi yayitali akuphatikizapo Humulin-basal, Biosulin N, Protofan NM. Zochita zawo zimatha mpaka maola 24, zomwe zimachitika patatha maola 2-2,5 pambuyo pa dongosolo. Oimira kukonzekera kwakutali - Lantus, Levemir.
Dongosolo la chithandizo cha munthu payekha limaperekedwa ndi adokotala. Zimatengera izi:
- zolimbitsa thupi
- kulemera thupi
- nthawi yopanga hyperglycemia,
- kukhalapo kwa shuga wamkulu mutatha kudya,
- zaka odwala
- kukhalapo kwa chodabwitsa cha "m'bandakucha."
Zithandizo zamankhwala
Nkhani zaposachedwa kwambiri pochiza matenda a shuga omwe amadalira insulin amati kugwiritsa ntchito njirazi:
- Kugwiritsa ntchito maselo a tsinde. Iyi ndi njira yodalirika yomwe mungathetsere mavuto a matenda a carbohydrate metabolism. Chinsinsi chake ndikukula maselo achinsinsi a insulin m'malo oberekera. Njira imeneyi imagwiritsidwa ntchito kwambiri ku China, Germany, USA.
- Kuthiridwa kwamafuta a brown ndi njira yatsopano yomwe imachepetsa kufunikira kwa thupi kwa insulin ndikubwezeretsa kagayidwe kazakudya. Njira zimachitika chifukwa chogwirika ndi mamolekyulu a shuga ndi maselo a bulauni.
- Katemera. Katemera wapadera wapangidwa yemwe amayang'anira kuteteza maselo a pancreatic kuti asawonongeke ndi chitetezo cha mthupi. Zinthu zomwe zimagwiritsidwa ntchito zimalepheretsa kutukusira kwa thupi ndikuletsa kupititsa patsogolo kwa matendawa.
Physiotherapy
Njira imodzi yochizira matenda ashuga. Nthawi zambiri, odwala amapatsidwa electrophoresis. Iyi ndi njira yochokera pakukhudzana ndi mankhwalawa. Potengera maziko a "matenda okoma" amagwiritsidwa ntchito electrophoresis a zinc, mkuwa ndi potaziyamu. Kudzimbidwa kumakhala ndi phindu pa zomwe zimachitika mthupi, kumapangitsa kagayidwe kachakudya ka magazi, kumachepetsa glycemia.
Potaziyamu electrophoresis ndiyofunikira kubwezeretsanso kuchuluka kwa kufufuza zinthu mthupi chifukwa cha kuphipha kwake mkodzo. Magnesium imafunika pakuyenda bwino kwa kagayidwe, kayendedwe ka cholesterol ndi shuga, komanso kusintha kwa kapamba. Ngati angiopathy yam'munsi yotsika imagwiritsidwa ntchito, electrophoresis ya sodium thiosulfate kapena novocaine imagwiritsidwa ntchito, chifukwa chomwe kupweteka kumachepetsedwa, ndipo zimatha kugwiritsidwa ntchito ndi anti-sclerotic.
Magnetotherapy imagwiritsidwa ntchito kwambiri, yomwe imakhala ndi analgesic, immunomodulating and angioprotective zotsatira. Inductothermy (pogwiritsa ntchito maginito otchuka pafupipafupi) ndikofunikira kukonza kukoka kwa magazi ndi zamitsempha. Hyperbaric oxygenation (kugwiritsa ntchito mpweya wopanikizika kwambiri) kumakuthandizani kuti muchepetse mitundu yosiyanasiyana ya hypoxia, sinthani chikhalidwe cha wodwalayo, muchepetse insulin ndi mankhwala ena omwe amagwiritsidwa ntchito, kusintha kayendedwe ka magazi ndikuyambitsa kupanikizika.
Kuperekera mankhwala ndi chithandizo chinanso chothandiza. Singano amagwiritsidwa ntchito pochiza neuropathy. Ndikofunikira kukonza conduction ya mitsempha, kuwonjezera mphamvu zam'munsi zam'munsi, komanso kuchepetsa kuwawa. Pazifukwa zomwezo, acupressure, electroacupuncture ndi laser acupuncture amagwiritsidwa ntchito.
Njira yotsatira ndi plasmapheresis. Njirayi imakhala m'lingaliro lakuti magazi amwazi amachotsedwa ndikuyika m'malo mwa plasma. Mankhwalawa amagwira ntchito motsutsana ndi maziko a kulephera kwa impso ndi kusokonekera kwa zovuta. Njira ina yochizira ndi balneotherapy (pogwiritsa ntchito madzi achilengedwe kapena okonzedwa mwakapangidwe), yomwe ndi gawo la mankhwala a spa.
Zithandizo za anthu
Kuchiza ndi wowerengeka azitsamba kuyenera kuchitika motsogozedwa ndi katswiri woyenera. Kudziletsa sikulimbikitsidwa pankhaniyi. Maphikidwe otsatirawa ndi otchuka.
Chinsinsi 1
Chinyengo cha maluwa a linden. Zinthu zosafunikira zimathiridwa ndi madzi muyezo wa kapu ya maluwa pa lita imodzi yamadzi. Wiritsani kwa mphindi 15, ndipo pambuyo pozizira, sokoneza ndikuchepera pang'ono tsiku lonse.
Chinsinsi 2
Onjezani ndodo ya sinamoni ku kapu yamadzi otentha, tsimikizirani kwa theka la ola. Kenako yambitsani supuni ya uchi ndikuyimira njira ina kwa maola atatu. Tengani masana pang'ono.
Chinsinsi chachitatu
Ndikofunikira kukonzekera chisakanizo cha dzira limodzi laiwisi laiwisi ndi kapu imodzi ya mandimu. Wothandizirana chotere amachepetsa shuga m'magazi. Amatenga ola limodzi asanadye chakudya cham'mawa.
Tsoka ilo, akafunsidwa ngati matenda a shuga angathe kuchiritsidwa, mankhwala amakono sangapereke yankho. Pali njira zingapo zingapo, komabe, ambiri aiwo akupitabe patsogolo. Mitundu yathunthu yosankhidwa ndi adotolo ithandizanso kulipirira matendawa, kupewa kutengera zovuta komanso kukhalabe ndi moyo wabwino wodwala pamlingo wambiri.
Lumikizanani ndi nkhani: http://www.mk.ru/science/article/2013/07/03/878571-novaya-vaktsina-zastavlyaet-organizm-diabetikov-vyirabatyivat-insulin-samostoyatelno.html
Kwenikweni nkhani zokha.
Ma syringe adzakhala chinthu chakale - katemera watsopano wa DNA wayesedwa bwino mwa anthu
Chifukwa chopanga njira yatsopano yothandizira, anthu omwe ali ndi matenda amtundu wa 1 posachedwa amatha kuiwala za syringes ndi jakisoni wokhazikika wa insulin. Pakadali pano, Dr. Lawrence Steinman ochokera ku yunivesite ya Stanford adati njira yatsopano yothandizira matenda a shuga 1 yayesedwa bwino mwa anthu ndipo angagwiritsidwe ntchito kwambiri pochiza matendawa mtsogolo.
matenda a shuga 1 matenda a shuga a insulin lawrence steinman katemera Lawrence steinman neurology
Lawrence Steinman, M.D./ Stanford University
Katemera yemwe amatchedwa "reverse katemera" amagwira ntchito mwa kutsinikiza chitetezo cha mthupi pa DNA, zomwe zimapangitsa kuti insulini ipangidwe. Kukula kwa yunivesite ya Stanford ikhoza kukhala katemera woyamba wa DNA padziko lapansi yemwe angagwiritsidwe ntchito pochiritsa anthu.
“Katemera uyu amatengera njira ina. Limaletsa mayankho enieni a chitetezo cha mthupi, ndipo sizimapanga mayankho achindunji ngati katemera wamba kapena katemera wa polio, "atero a Lawrence Steinman.
Katemera anayesedwa pagulu la odzipereka 80. Maphunzirowa adachitika zaka ziwiri ndikuwonetsa kuti odwala omwe amalandila chithandizo malinga ndi njira yatsopanoyo akuwonetsa kuchepa kwa ntchito yama cell omwe amawononga insulin mthupi. Nthawi yomweyo, kunalibe zotsatila atamwa katemera.
Monga momwe dzinalo likunenera, katemera wothandizira sanapangidwe kuti apewe matenda, koma kuthandiza matenda omwe alipo.
Asayansi, atazindikira mitundu iti ya leukocytes, "asirikali" oyamba a chitetezo cha mthupi, omwe amagwidwa ndi kapamba, apanga mankhwala omwe amachepetsa kuchuluka kwa maselo amenewa m'magazi osakhudza mbali zina za chitetezo cha mthupi.
Ophunzira nawo pa mayeso kamodzi pa sabata kwa miyezi itatu adalandira jakisoni wa katemera watsopano. Mofananamo, anapitiliza kupeleka insulin.
Gulu lolamulira, odwala omwe amalandira jakisoni wa insulin amalandira mankhwala a placebo m'malo mwa katemera.
Omwe amapanga katemerayu akuti mgulu loyesera lomwe limalandira mankhwalawo, panali kusintha kwakukulu pakugwira ntchito kwa maselo a beta, omwe pang'onopang'ono adabwezeretsa kutulutsa insulin.
"Tatsala pang'ono kukwaniritsa maloto a dotolo aliyense: taphunzira kuyesa kuzimitsa kachipangizidwe ka chitetezo chathupi osakhudza kugwira ntchito kwake konse," anatero a Lawrence Steinman, m'modzi mwa olemba zomwe apezazi.
Matenda a shuga a Type 1 amadziwika kuti ndi matenda oopsa kwambiri kuposa matenda a shuga a "mnzake".
Mawu oti shuga pawokha amatengedwa kuchokera ku mawu achi Greek akuti "diabayo," omwe amatanthauza "ndikudutsa kena kake,", "kuyenda". Dokotala wakale Areteus wa ku Cappadocia (30 ... 90 AD) adawonera odwala polyuria, omwe adalumikizidwa ndi zakuti madzi omwe amalowa mthupi amayenda kudzera mwa iwo ndipo amawonetsedwa osasinthika. Mu 1600 AD e. shuga idawonjezeredwa ku liwu loti mellitus (kuchokera lat. mel - uchi) kutanthauza shuga ndi mkoma wokoma wa mkodzo - shuga.
Matenda a shuga a insipidus anali odziwika kale ngati zakale, koma mpaka m'zaka za zana la 17 kunalibe kusiyana pakati pa matenda ashuga ndi insipidus. Mu XIX - koyambirira kwa zaka za XX, ntchito yochulukirapo pa matenda a shuga insipidus idawonekera, kulumikizana kwa matendawa ndi matenda am'mimba am'mimba komanso chothandizira cha pituitary gland idakhazikitsidwa. M'mafotokozedwe azachipatala, mawu akuti "matenda ashuga" nthawi zambiri amatanthauza ludzu ndi matenda ashuga (matenda ashuga komanso matenda a shuga), komabe "pamadutsa" - matenda a shuga a phosphate, matenda a impso (chifukwa cha malire ochepa a shuga, osayenda ndi matenda ashuga), ndi zina zambiri.
Mwachindunji lembani 1 shuga mellitus ndi matenda omwe chizindikiritso chake chachikulu ndi hyperglycemia - shuga wambiri, polyuria, chifukwa chomwe mumamva ludzu, kuchepa thupi, kulakalaka kwambiri, kapena kusowa kwake, thanzi labwino. Matenda a shuga amapezeka matenda osiyanasiyana omwe amatsogolera kuchepa kwa kaphatikizidwe ndi katemera wa insulin. Udindo wa cholowa chofufuzira ukufufuzidwa.
Matenda a shuga a Type 1 amatha kukhala ndi zaka zilizonse, koma anthu azaka zazing'ono kwambiri (ana, achinyamata, achikulire osakwana 30) nthawi zambiri amakhudzidwa. Makina a pathogenetic omwe amapanga chitukuko cha matenda a shuga 1 amachokera pa kuperewera kwa insulin yopanga ma cell a endocrine (β-cell of islets of Langerhans of the pancreas), omwe amayamba chifukwa cha kuwonongeka kwawo motsogozedwa ndi zinthu zina za pathogenic (matenda a virus, nkhawa, matenda a autoimmune ndi ena).
Mtundu woyamba wa matenda a shuga umakhala ndi 10% ya matenda onse a shuga, nthawi zambiri amakula ubwana kapena unyamata. Njira yayikulu yothandizira ndi majakisoni a insulin omwe amateteza kagayidwe ka wodwala. Ngati sichichiritsidwenso, matenda ashuga amtundu wa 1 amakula msanga ndipo amadzetsa mavuto akulu, monga ketoacidosis ndi chikomokere matenda a shuga, zomwe zimapangitsa kuti wodwalayo afe.
ndipo tsopano zowonjezera mwachidule. Inenso ndili ndi matenda ashuga kwa zaka 16. zinandibweretsera mavuto ambiri m'moyo, ngakhale zinali zofunikanso. Popanda matenda, sindikadakhala kuti ndine ndani. Sindikadaphunzila kudziletsa kwamtunduwu, sindikadakhala okhwima pamaso pa anzanga ... koma zinthu zambiri. Aaah, ndikupemphera kuti akatswiri azamalonda omwe amapanga ndalama zochulukirapo pamwayiwu asawononge nkhaniyi. Ndikulakalaka odwala onse atha kukhala ndi moyo mpaka nthawi yabwino yomwe matendawa achira. anyamata ophika onse))