Kukonzekera kwa insulin Humulin M3 insulini imapezeka mu mawonekedwe a kuyimitsidwa kwa ma subcutaneous makonzedwe mu 10 ml mabotolo, komanso 1.5 ndi 3 ml makatoni, oikidwa m'mabokosi a 5 zidutswa. Cartridges adapangidwa kuti azigwiritsa ntchito syringes ya Humapen ndi BD-pen.

Mankhwala ali ndi hypoglycemic.

Humulin M3 amatanthauza mankhwala obwerezabwereza a DNA, insulin ndi kuyimitsidwa kwa jekeseni kawiri ndi nthawi yayitali.

Pambuyo mankhwala, mankhwala kukonzekera kumachitika pambuyo 30-60 Mphindi. Kuchuluka kwake kumatenga maola awiri mpaka 12, kutalika kwa zotsatirazi ndi maola 18-24.

Ntchito za humulin insulin zimatha kusiyanasiyana malinga ndi malo omwe mankhwalawo amaperekera, kulondola kwa mlingo wosankhidwa, zochita za thupi, wodwala, zina ndi zina.

Zotsatira zazikulu za Humulin M3 zimagwirizana ndi kayendedwe ka kusintha kwa shuga. Insulin ilinso ndi anabolic. Pafupifupi minofu yonse (kupatula ubongo) ndi minofu, insulin imayendetsa kayendedwe ka glucose ndi amino acid, komanso imayambitsa kuthamanga kwa protein anabolism.

Insulin imathandizira kusintha glucose kukhala glycogen, komanso imathandizira kusintha shuga yambiri kukhala mafuta ndikuletsa gluconeogeneis.

Zizindikiro zamagwiritsidwe ntchito ndi zoyipa

Shuga mellitus, momwe insulin tikulimbikitsidwa.
(matenda ashuga).

Kukhazikika hypoglycemia.
Hypersensitivity.

Nthawi zambiri pa mankhwala akukonzekera insulin, kuphatikiza Humulin M3, kukula kwa hypoglycemia kumawonedwa. Ngati ili ndi mawonekedwe owopsa, imatha kudzutsa chikumbumtima cha hypoglycemic (kuponderezana ndi kusazindikira) ngakhale kupangitsa kuti wodwalayo afe.

Mwa odwala ena, thupi lawo siligwirizana, kuwoneka pakuluma pakhungu, kutupa ndi kufupika kwa malo a jakisoni. Nthawi zambiri, matendawa amadzidzidzikira okha patatha masiku kapena milungu yochepa atayamba chithandizo.

Nthawi zina izi sizimalumikizana ndi kugwiritsa ntchito mankhwalawo pawokha, koma ndi chifukwa cha mphamvu ya zinthu zakunja kapena jakisoni wolakwika.

Pali ziwonetsero zomwe sizigwirizana ndi zachilengedwe. Amachitika kawirikawiri, koma zowopsa. Ndi malingaliro otere, zotsatirazi zimachitika:

kuvutika kupuma
kuyamwa kofananira
kugunda kwa mtima
dontho mu kuthamanga kwa magazi
kupuma movutikira
thukuta kwambiri.

Milandu yoopsa kwambiri, chifuwa chimatha kusokoneza moyo wa wodwalayo ndipo imafunikira chithandizo chamankhwala mwadzidzidzi. Nthawi zina insulin m'malo kapena desensitization chofunika.

Mukamagwiritsa ntchito insulin ya nyama, kukana, hypersensitivity kwa mankhwala, kapena lipodystrophy imayamba. Mukamapereka insulin Humulin M3, kuthekera kwa zotulukazi ndi pafupifupi zero.

Malangizo ogwiritsira ntchito

Insulin ya Humulin M3 saloledwa kuti iperekedwe kudzera m'mitsempha.

Popereka mankhwala a insulin, muyezo ndi mtundu wa makonzedwe ungasankhidwa ndi dokotala. Izi zimachitika payekhapayekha kwa wodwala aliyense payekhapayekha, kutengera mtundu wa glycemia m'thupi lake. Humulin M3 idapangidwa kuti ikwaniritse kayendetsedwe ka subcutaneous, koma imathanso kuperekedwa kudzera mwa intramuscularly, insulin ilola izi. Mulimonsemo, odwala matenda ashuga ayenera kudziwa.

Pang'onopang'ono, mankhwalawa amalowetsedwa pamimba, ntchafu, phewa kapena matako. Mu malo omwewo jakisoni sangaperekedwe mopitilira kamodzi pamwezi. Panthawi ya ndondomekoyi, ndikofunikira kugwiritsa ntchito zida za jakisoni moyenera, kuti singano isalowe m'mitsempha yamagazi, kuti musamayesere malo a jekeseni pambuyo pobayira.

Humulin M3 ndi osakaniza wopangidwa ndi Humulin NPH ndi Humulin Regular. Izi zimapangitsa kuti asakonzekere yankho lisanayambike kwa wodwalayo.

Kukonzekera insulin ya jakisoni, vial kapena cartridge ya Humulin M3 NPH iyenera kukukhidwira maulendo 10 mmanja mwanu, ndikutembenuka, madigiri a 180, gwedezani pang'ono ndi pang'ono. Izi zikuyenera kuchitika mpaka kuyimitsidwa kumakhala ngati mkaka kapena kukhala kwamtambo, ndimadzi amodzimodzi.

Makulidwe a insulin

Kuti mupeze jakisoni moyenera mankhwalawo, muyenera kuchita njira zina zoyambirira. Choyamba muyenera kudziwa malo omwe jakisoniyo, sambani manja anu ndikupukuta malowa ndi nsalu yothinidwa ndimowa.

Kenako muyenera kuchotsa kapu yoteteza ku singano ya syringe, kukonza khungu (kutambasula kapena kutsina), ikani singano ndikupanga jakisoni. Kenako singano iyenera kuchotsedwa ndipo masekondi angapo, osafunikira, kanikizani tsamba la jekeseni ndi chopukutira. Pambuyo pake, mothandizidwa ndi kapu yakunja yoteteza, muyenera kumasula singano, kuichotsa ndikubwezeranso chipewa pa syringe.

Simungagwiritse ntchito singano yemweyo ya syringe kawiri. Vial kapena cartridge imagwiritsidwa ntchito mpaka itapanda kanthu, ndiye kuti imatayidwa. Ma cholembera a syringe adapangira kuti azigwiritsa ntchito payekha.

Bongo

Humulin M3 NPH, monga mankhwala ena omwe ali mgululi. Komabe, imatha kukhala ndi zochita zoyipa kwambiri.

Hypoglycemia imayamba chifukwa cha kusamvana pakati pa zomwe zili ndi insulin m'magazi a plasma ndi mtengo wamagetsi komanso kudya.

Zizindikiro zotsatirazi ndizodziwika za hypoglycemia:

ulesi
tachycardia
kusanza
thukuta kwambiri,
kukopa kwa pakhungu
kunjenjemera
mutu
chisokonezo.

Nthawi zina, mwachitsanzo, ndi mbiri yayitali ya matenda a shuga kapena kuyang'anitsitsa kwake, Zizindikiro za kutha kwa hypoglycemia zimatha kusintha. Hypoglycemia yofatsa imatha kupewedwa pakutenga shuga kapena shuga. Nthawi zina mungafunikire kusintha kuchuluka kwa insulini, kuunikanso zakudya kapena kusintha zolimbitsa thupi.

Hypoglycemia wolimbitsa thupi nthawi zambiri amathandizidwa ndi subcutaneous kapena mu mnofu makonzedwe a glucagon, otsatiridwa ndi kudya kwa carbohydrate. Woopsa milandu, pamaso pa matenda a mitsempha, kukomoka kapena chikomokere, kuwonjezera pa jakisoni wa glucagon, kugwirizira kwa glucose kuyenera kuperekedwa mwachangu.

M'tsogolomo, pofuna kupewa kubwereranso kwa hypoglycemia, wodwalayo ayenera kudya zakudya zopatsa thanzi. Mikhalidwe yayikulu kwambiri ya hypoglycemic imafuna kuchipatala mwadzidzidzi.

Zochita Zamankhwala NPH

Kugwiritsa ntchito kwa Humulin M3 kumatheka chifukwa chokhala ndi mankhwala amkamwa a hypoglycemic, ethanol, zotumphukira za asidi wa asidi, zotsekemera za monoamine oxidase, sulfonamides, ACE inhibitors, angiotensin II receptor blockers, osasankha beta-blockers.

Mankhwala a Glucocorticoid, mahomoni akukula, njira zakulera zam'mlomo, danazole, mahomoni a chithokomiro, thiazide diuretics, beta2-sympathomimetics amatsogolera kuchepa kwa mphamvu ya hypoglycemic ya insulin.

Limbitsani kapena, mutafooketsa kudalira insulin yomwe imatha lancreotide ndi ma analogu ena a somatostatin.

Zizindikiro za hypoglycemia zimatsitsidwa ndikutenga clonidine, reserpine ndi beta-blockers.

Migwirizano yogulitsa, yosungirako

Humulin M3 NPH imapezeka pa pharmacy pokhapokha ngati mwalandira mankhwala.

Mankhwalawa amayenera kusungidwa pamtunda wa madigiri 2 mpaka 8, sangathe kuwundana ndikuwonetsa kuwala kwa dzuwa ndi kutentha.

Vial yotsegulidwa ya NPH imatha kusungidwa pamtunda wa 15 mpaka 25 digiri masiku 28.

Kutengera ndi kutentha kofunikira, kukonzekera kwa NPH kumasungidwa zaka 3.

Malangizo apadera

Kuchotsa mosavomerezeka kwa chithandizo kapena kusankhidwa kwa mankhwala olakwika (makamaka odwala omwe akudalira insulin) kungayambitse kukula kwa matenda ashuga a ketoacidosis kapena hyperglycemia, omwe angawononge moyo wa wodwalayo.

Mwa anthu ena, mukamagwiritsa ntchito insulin yaumunthu, zizindikiro za hypoglycemia zomwe zikubwera zimatha kusiyana ndi zomwe zimadziwika ndi insulin yakuchokera kwa nyama, kapena zitha kukhala zowonetsera pang'ono.

Wodwalayo ayenera kudziwa kuti ngati shuga ya m'magazi imasintha (mwachitsanzo, ndi insulin yokwanira), ndiye kuti zizindikiro zomwe zikutanthauza kuti hypoglycemia ikhoza kutha.

Mawonetsedwe awa amatha kuchepera mphamvu kapena kuwoneka mosiyanasiyana ngati munthu atenga mankhwala a beta-blockers kapena ali ndi matenda osokoneza bongo a nthawi yayitali, komanso pamaso pa matenda a shuga.

Ngati, monga hypoglycemia, osakonzedwa munthawi yake, izi zitha kuchititsa kuti musakhale ndi chikumbumtima, chikomokere, ngakhale kufa kwa wodwalayo.

Wodwalayo asinthana ndi mankhwala ena a insulin NPH kapena mitundu yawo kokha moyang'aniridwa ndi dokotala. Kusintha kwa insulin ngati mankhwala ndi ntchito ina, njira yopangira (DNA recombinant, nyama), mitundu (nkhumba, analog) ingafune mwadzidzidzi kapena, m'malo mwake, kukonza kosavomerezeka kwa waukulu.

Ndi matenda a impso kapena chiwindi, kusakwanira kwa ntchito ya pituitary, kugwira ntchito kwa minyewa ya adrenal komanso chithokomiro cha chithokomiro, kufunikira kwa insulin kumatha kuchepa, komanso kupsinjika mwamphamvu ndi zina.

Wodwala nthawi zonse ayenera kukumbukira mwayi wokhala ndi hypoglycemia ndikuwunika bwino momwe thupi lake limayendetsa galimoto kapena kufunika kwa ntchito yoyipa.

Monodar (K15, K30, K50),
Novomix 30 Flexspen,
Ryzodeg Flextach,
Humalog Remix (25, 50).
Gensulin M (10, 20, 30, 40, 50),
Gensulin N,
Rinsulin NPH,
Farmasulin H 30/70,
Humodar B,
Vosulin 30/70,
Vosulin N,
Mikstard 30 NM
Humulin.

Mimba komanso kuyamwa

Ngati mayi woyembekezera ali ndi matenda ashuga, ndiye kuti ndikofunikira kwambiri kuti azilamulira glycemia. Pakadali pano, zofuna za insulin nthawi zambiri zimasintha nthawi zosiyanasiyana. Mu trimester yoyamba, imagwera, ndipo chachiwiri ndi chachitatu chikuwonjezeka, kotero kusintha kwa mankhwalawa kungakhale kofunikira.

Humulin NPH ndi mankhwala ena a gululi amapanga mankhwala omwe amagwiritsidwa ntchito pochiritsa anthu omwe ali ndi matenda ashuga. Mankhwala ali ndi katundu wachilengedwe wochepetsa shuga, popeza amapangidwa pamaziko a insulin yaumunthu. Cholinga chachikulu cha zinthu zopangidwa mwaluso ndi kuchepetsa kuchuluka kwa shuga m'magazi ndikulowetsa mu minofu ndikuyiphatikiza ndi zochita za maselo.

Humulin ndi chiyani?

Masiku ano, mawu akuti Humulin amatha kuwoneka mu mayina a mankhwala angapo omwe amapangidwa kuti achepetse shuga ya magazi - Humulin NPH, MoH, pafupipafupi komanso Ultralent.

Kusiyana kwa njira zopangira mankhwalawa kumapereka mawonekedwe aliwonse ochepetsa shuga ndi zomwe ali nazo. Izi zimazindikiridwa popereka mankhwala kwa anthu odwala matenda ashuga. Mankhwala, kuphatikiza insulin (gawo lalikulu, loyesedwa mu IU), zinthu zothandizira zilipo, izi zitha kukhala zosalimba zamadzimadzi, ma protein, carbolic acid, metacresol, zinc oxide, sodium hydroxide, etc.

Horoni ya pancreatic imayikidwa m'makalata, mbale, ndi zolembera. Malangizo omwe aphatikizidwa amadziwitsa za zomwe amagwiritsidwa ntchito ngati mankhwala a anthu. Musanagwiritse ntchito, makatoni ndi mbale siziyenera kugwedezeka mwamphamvu;Choyenera kwambiri chogwiritsidwa ntchito ndi odwala matenda ashuga ndi cholembera.

Kugwiritsa ntchito mankhwala omwe atchulidwa kumathandizira kuti zitheke kupeza chithandizo chokwanira kwa odwala omwe ali ndi matenda ashuga, chifukwa amathandizira kuti pakhale kuperewera kwathunthu komanso kuperewera kwa mphamvu ya amkati amkati. Fotokozerani Himulin (mlingo, regimen) ayenera kukhala wa endocrinologist. M'tsogolo, ngati pakufunika kutero, dokotala yemwe akukonzekera akhoza kuwongolera njira yochizira.

Mu matenda a shuga a mtundu woyamba, insulin imaperekedwa kwa munthu moyo wonse. Ndi zovuta za mtundu wa 2 shuga, zomwe zimayendera limodzi ndi matenda amtundu wa concomitant, mankhwalawa amapangidwa kuchokera ku maphunziro osiyanasiyana. Ndikofunika kukumbukira kuti ndi matenda omwe amafunikira kukhazikitsa mahomoni opanga thupi m'thupi, simungakane mankhwala a insulini, apo ayi mavuto akulu sangathe kupewedwa.

Mtengo wa mankhwalawa gulu lama pharmacological zimatengera nthawi yochitapo ndi mtundu wa ma CD. Mtengo wowerengeka m'mabotolo umayambira ku ma ruble 500., mtengo wake m'matotolo - kuchokera ku ma ruble 1000., M'mapensulo a syringe ndi osachepera 1500 rubles.

Kuti mudziwe mlingo ndi nthawi ya kumwa mankhwalawa, muyenera kulumikizana ndi endocrinologist

Zonse zimatengera zosiyanasiyana

Mitundu ya ndalama ndi zotsatira zake pakathupi zimafotokozedwa pansipa.

Mankhwalawa amapangidwa pogwiritsa ntchito ukadaulo wama DNA ndipo amakhala ndi nthawi yayitali. Cholinga chachikulu cha mankhwalawa ndikukhazikitsa kagayidwe ka glucose. Imathandizira kuti muchepetse kusweka kwa mapuloteni ndipo imakhudzanso minofu ya thupi. Humulin NPH imawonjezera ntchito ya ma enzyme omwe amalimbikitsa mapangidwe a glycogen mu minofu minofu. Kuchulukitsa kuchuluka kwa mafuta acids, kumakhudza kuchuluka kwa glycerol, kumathandizira kupanga mapuloteni komanso kumalimbikitsa kumwa ma aminocarboxylic acid ndi maselo amisempha.

Ma Analogs omwe amachepetsa shuga la magazi ndi:

Actrafan NM.
Diafan ChSP.
Wofukiza N.
Protafan NM.
Humodar B.

Pambuyo jekeseni, yankho limayamba kugwira ntchito pambuyo pa ola limodzi, mphamvu zonse zimachitika mkati mwa maola 2-8, chinthucho chimakhalabe chogwira ntchito kwa maola 18-20. Nthawi yakukonzekera kwa mahomoni kutengera mlingo womwe wagwiritsidwa ntchito, tsamba la jakisoni, ndi zochita za anthu.

Humulin NPH akuwonetsedwa kuti agwiritse ntchito:

Matenda a shuga omwe ali ndi insulin.
Woyamba anapeza matenda a shuga.
Amayi oyembekezera omwe ali ndi matenda osokoneza bongo omwe amadalira insulin.

Malangizowo akuti mankhwalawa saikidwa kwa anthu omwe ali ndi vuto la hypoglycemia, lomwe limadziwika ndi kutsika kwa magazi m'munsi mwa 3.5 mmol / l, m'magazi otumphukira - 3,3 mmol / l, kwa odwala omwe ali ndi hypersensitivity kwa zigawo zina za mankhwala.
Zotsatira zoyipa zomwe zingachitike mutagwiritsa ntchito mankhwalawa nthawi zambiri zimawonetsedwa:

Hypoglycemia.
Kuwonongeka kwamafuta.
Zokhudza zonse komanso zam'deralo.

Ponena za mankhwala osokoneza bongo a mankhwalawa, palibe zizindikiro zenizeni za kumwa mopitirira muyeso. Zizindikiro zazikuluzikulu zimadziwika ngati chiyambi cha hypoglycemia. Vutoli limaphatikizidwa ndi kupweteka kwamutu, tachycardia, thukuta lotupa komanso khungu. Popewa zovuta zotere, dokotala amasankha kuchuluka kwa wodwala aliyense payekhapayekha, poganizira kuchuluka kwa glycemia.

Ndi mankhwala osokoneza bongo ambiri, hypoglycemia ingachitike.

Humulin M3, monga mankhwala am'mbuyomu, adapangidwa nthawi yayitali. Imadziwika mu mawonekedwe a kuyimitsidwa kwamitundu iwiri, ma cartridge agalasi amakhala ndi insulin humulin pafupipafupi (30%) ndi humulin-nph (70%). Cholinga chachikulu cha Humulin Mz ndikuwongolera kagayidwe ka glucose.

Mankhwalawa amathandizira kupanga minofu, imatulutsa shuga ndi aminocarboxylic acid m'maselo a minofu ndi minyewa ina kupatula ubongo. Humulin M3 imathandizira mu minofu ya chiwindi kuti isinthe glucose kukhala glycogen, imalepheretsa gluconeogeneis ndikusintha glucose owonjezereka kukhala subcutaneous ndi visceral fat.

Zotsatira za mankhwalawa ndi:

Protafan NM.
Farmasulin.
Actrapid Flekspen.
Lantus Optiset.

Pambuyo pakubaya, Humulin M3 imayamba kugwira ntchito pambuyo pa mphindi 30-60, mphamvu kwambiri imapezeka mkati mwa maola 2-12, nthawi ya insulini ndi maola 24. Zomwe zimakhudza kuchuluka kwa zochita za Humulin m3 zimagwirizanitsidwa ndi malo osankhidwa a jakisoni ndi Mlingo, ndi zochitika zolimbitsa thupi za munthu ndi chakudya chake.

Anthu omwe ali ndi matenda ashuga omwe amafunikira chithandizo cha insulin.
Amayi oyembekezera omwe ali ndi matenda ashuga.

Neutral insulini zothetsera zimaphatikizidwa pakupezeka hypoglycemia ndi hypersensitivity pazomwe zimapangidwira. Mankhwala a insulin amayenera kuchitika moyang'aniridwa ndi dokotala, omwe amachotsa kukula ndi kusokonezeka kwa hypoglycemia, komwe kumatha, kukhala chifukwa cha kukhumudwa komanso kutaya chikumbumtima, zoyipa kwambiri - kuyambanso kumwalira.

Mankhwala a insulin, odwala amatha kuyanjana ndi kwawo, komwe nthawi zambiri kumawonekera pakuluma, kusungunuka, kapena kutupira khungu pakhungu. Khungu limakhala yofanana pakadutsa masiku 1-2, pamavuto ena pamafunika masabata angapo. Nthawi zina zizindikirozi ndi chizindikiro cha jakisoni wolakwika.

Kuchepa kwachilengedwe kumachitika pang'onopang'ono nthawi zambiri, koma mawonekedwe ake ndi akulu kwambiri kuposa omwe adakumana nawo, monga kuyabwa kofulumira, kupuma movutikira, kuthamanga magazi, thukuta kwambiri komanso kuthamanga mtima. Mu zochitika zapadera, ziwengo zimatha kusokoneza moyo wa munthu, vutolo limakonzedwa ndi chithandizo chadzidzidzi, kugwiritsidwa ntchito mwaumoyo ndi kugwiritsa ntchito mankhwala osokoneza bongo.

Mankhwalawa amalembera anthu omwe akufuna insulin.

Humulin regula - kuchita mwachidule

Humulin P ndi mtundu wopangidwira wa DNA wokhala ndi nthawi yayifupi. Cholinga chachikulu ndikukhazikitsa kagayidwe ka glucose. Ntchito zonse zomwe zimaperekedwa kwa mankhwalawa ndizofanana ndi mfundo yodziwitsidwa ndi ma humulin ena. Njira yothetsera vutoli ikuwonetsedwa kuti igwiritsidwe ntchito ndi anthu omwe ali ndi matenda osokoneza bongo a mtundu woyamba komanso wachiwiri, ndikulimbana ndi thupi pakumwa mankhwala a hypoglycemic.
Humulin regula wasankhidwa:

Ndi matenda ashuga ketoacidosis.
Ketoacidotic ndi hyperosmolar chikomokere.
Ngati matenda ashuga adawoneka panthawi yobala mwana (kutengera kulephera kwa zakudya).
Ndi njira yaposachedwa yochizira matenda a shuga.
Mukasinthira ku insulin yowonjezera.
Pamaso pa opareshoni, ndi zovuta za metabolic.

Humulin P imaphatikizidwa chifukwa cha hypersensitivity pamagulu a mankhwala ndipo amadziwika kuti ali ndi hypoglycemia. Dokotala payekhapayekha amalembera wodwalayo mlingo ndi mtundu wa jakisoni poganizira kuchuluka kwa shuga m'magazi asanadye komanso pambuyo pa maola 1-2 atatha. Kuphatikiza apo, pakadutsa mlingo, kuchuluka kwa shuga mkodzo ndi mawonekedwe a nthawi ya matendawa amakhudzidwa.

Wothandiziridwayo, mosiyana ndi omwe adakumana nawo, amatha kutumikiridwa intramuscularly, subcutanely and intrarally. Njira yodziwika kwambiri yoyendetsera ndi yodutsa. Ndi mitundu yovuta ya matenda ashuga komanso chikomokere cha matenda ashuga, njira za IV ndi IM zimakonda. Ndi monotherapy, mankhwalawa amatumizidwa katatu pa tsiku. Pofuna kupatula kupezeka kwa lipodystrophy, malo a jakisoni amasinthidwa nthawi iliyonse.

Humulin P, ngati pakufunika, imaphatikizidwa ndi mankhwala a mahomoni amtundu wa nthawi yayitali. Zofananira za mankhwala:

Actrapid NM.
Biosulin R.
Insuman Rapid GT.
Rosinsulin R.

Mankhwalawa amadziwitsidwa ndikusintha kwa insulin yayitali

Mtengo wa izi m'malo umayamba kuchokera ku ma ruble 185, Rosinsulin amadziwika kuti ndiwodula kwambiri, mtengo wake lero ndi oposa ruble 900. M'malo insulin ndi analogue ziyenera kuchitika ndi nawo madokotala.Analogue yotsika mtengo ya Humulin R ndi Actrapid, wotchuka kwambiri ndi NovoRapid Flekspen.

Humulinultralente wotalikirapo

Insulin Humulin ultralente ndi mankhwala ena omwe amawonetsedwa kuti agwiritsidwe ntchito kwa odwala omwe ali ndi matenda a shuga. Chogulitsidwachi chimakhudzidwa ndi DNA yomwe imapangidwanso ndipo ndi chinthu chomwe chimagwiritsidwa ntchito kwa nthawi yayitali. Kuyimitsidwa kumayambitsidwa patatha maola atatu jakisoni itatha, mphamvu yotsika imatheka mkati mwa maola 18. Malangizo ogwiritsira ntchito akuwonetsa kuti nthawi yayitali ya Humulinultralente ndi maola 24-28.

Dokotala amakhazikitsa mlingo wa mankhwala kwa wodwala aliyense payekhapayekha, poganizira momwe wodwalayo alili. Mankhwalawa amaperekedwa popanda kuwonjezeredwa, jakisoni amapangidwa pansi pa khungu kawiri pa tsiku. Humulin Ultralente akaphatikizidwa ndi mahomoni ena opanga, jakisoni amaperekedwa nthawi yomweyo. Kufunika kwa insulin kumawonjezeka ngati munthu akudwala, akukumana ndi zovuta, amatenga pakati pakamwa, glucocorticoids kapena mahomoni a chithokomiro. Ndipo, mmalo mwake, amachepetsa ndimatenda a chiwindi ndi impso, pomwe mukutenga ma MA inhibitors ndi beta-blockers.
Mndandanda wa mankhwalawa: Humodar K25, Gensulin M30, Insuman Comb ndi Farmasulin.

Ganizirani zotsutsana ndi zoyipa.

Monga ma humulin onse, Insulin Ultralente imapatsirana milandu ya hypoglycemia yosatha ndi chiwopsezo champhamvu cha zigawo zina za chinthu. Malinga ndi akatswiri, zotsatira zoyipa sizimadziwonetsera zokha kuti siziyenda bwino. Zotheka pambuyo pobayikiridwa ndi jakisoni wa lipodystrophy, momwe kuchuluka kwa minofu ya adipose mu minofu ya subcutaneous kumachepa, komanso kukana insulin.

Nthawi zina, mankhwalawa amayambitsa sayanjana.

Analogue yotchuka ya humulin - Protaphane

Insulin Protafan NM imawonetsedwa kwa matenda osokoneza bongo a mtundu woyamba ndi wachiwiri, pakulimbana kwa sulfonylurea, zotumphukira zamagulu a matenda ashuga, mu nthawi ya opaleshoni ndi yotsatila, kwa amayi apakati.

Protafan imaperekedwa kwa wodwala aliyense payekhapayekha, poganizira zosowa za thupi lake. Malinga ndi malangizo, kufunika kwa mlingo wowonjezera wa mahomoni ndi 0.3 - 1 IU / kg / tsiku.

Kufunika kumawonjezereka kwa odwala omwe ali ndi insulin kukokana (kuwonongeka kwa kagayidwe kazakudya ka maselo kupita ku insulin), nthawi zambiri izi zimachitika ndi odwala nthawi yakutha komanso kwa anthu omwe ali ndi kunenepa kwambiri. Kuwongolera mlingo wa mankhwalawa kutha kuchitika ndi adokotala ngati wodwala atayamba kudwala, makamaka ngati matenda akupatsirana. Mlingo umasinthidwa matenda a chiwindi, impso ndi matenda a chithokomiro. Protafan NM imagwiritsidwa ntchito ngati jekeseni wa subcutaneous mu monotherapy komanso kuphatikiza mwachidule kapena mwachangu.

Fomu ya Mlingo: & nbsp kuyimitsidwa kwa makulidwe osakanikira:

1 ml muli:

ntchito: insulin yamunthu 100 ME,

zokopa: metacresol 1.6 mg, phenol 0,65 mg, glycerol (glycerin) 16 mg, protamine sulfate 0,348 mg, sodium hydrogen phosphate heptahydrate 3,78 mg, zinc oxide - qs kuti apange zinc ions zosaposa 40 μg, 10% hydrochloric acid solution - Qs to pH 6.9-7.8, 10% sodium hydroxide solution - qs to pH 6.9-7.8, madzi a jakisoni - mpaka 1 ml.

Kuyimitsidwa ndi koyera, komwe kumachoka, ndikupanga koyera komanso kowoneka bwino - kopanda mawonekedwe kapena kopanda mtundu. Mtengo umasinthidwa mosavuta ndikugwedezeka modekha.

Gulu la Pharmacotherapeutic: wothandizila wa hypoglycemic - insulin ya nthawi yayitali yogwira ntchito ATX: & nbsp

A.10.A.C Kutalika kwapakatikati kosungira ndi mawonekedwe awo

Humulin® NPH ndi insulin yowerengeka ya anthu.

Chochita chachikulu cha insulin ndi kuphatikiza shuga kagayidwe.Kuphatikiza apo, imakhala ndi anabolic komanso anti-catabolic zotsatira zosiyanasiyana zamthupi. Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa ma amino acid, koma nthawi yomweyo kumachepa mu glycogenolysis, gluconeogeneis, ketogenesis, lipolysis, proteinabolism ndi kutulutsidwa kwa ma amino acid.

Humulin® NPH ndiakonzekereratu. Kukhazikika kwa mankhwala ndi ola limodzi pambuyo pa kukonzekera, mphamvu yayikulu imakhala pakati pa maola awiri ndi asanu ndi atatu, kutalika kwa nthawi ndi maola 18-20.

Kusiyana kwamwini pantchito ya insulin kumadalira zinthu monga mlingo, kusankha jakisoni, malo olimbitsa thupi, ndi zina zambiri.

Pharmacokinetics: kukwana kwathunthu kwa mayamwidwe ndi kuyambika kwa mphamvu ya insulin kumadalira malo a jakisoni (m'mimba, ntchafu, matako), mlingo (kuchuluka kwa insulin), kuchuluka kwa insulini mu mankhwala, etc. umagawidwa mosiyanasiyana kudutsa minyewa ndipo osadutsa chotchinga chachikulu komanso kulowa mkaka wa m'mawere. Amawonongedwa ndi insulinase makamaka m'chiwindi ndi impso. Amachotsa impso (30-80%). Zowonetsa:

- Matenda a shuga odwala matenda a insulin,

- matenda ashuga panthawi yoyembekezera.

Hypersensitivity kupita ku insulin kapena chimodzi mwazinthu za mankhwala,

Mimba ndi kuyamwa:

Pakati pa nthawi yayitali, ndikofunikira kuti pakhale chitetezo chabwino cha glycemic mwa odwala omwe amalandira insulin. Kufunika kwa insulin nthawi zambiri kumachepetsa panthawi yoyambirira ndikuwonjezeka panthawi yachiwiri komanso yachitatu. Nthawi yobadwa pambuyo pokhapokha ndipo mwayamba kubadwa, zofunika za insulin zimatha kugwa kwambiri. Odwala omwe ali ndi matenda ashuga amalangizidwa kuti azidziwitse dokotala wawo za kubereka kapena kukonzekera pakati.

Odwala omwe ali ndi matenda a shuga mellitus nthawi yoyamwitsa angafunikire kusintha mlingo wa insulin, zakudya, kapena zonse ziwiri.

Mlingo ndi makonzedwe:

Mlingo wa Humulin® NPH umatsimikiziridwa ndi dokotala aliyense payekha malinga ndi kuchuluka kwa shuga m'magazi. Mankhwalawa amayenera kuperekedwa mwachangu.

Kutentha kwa mankhwala omwe amaperekedwa kuyenera kukhala kutentha kwambiri.

Jakisoni wotsekemera uyenera kuchitidwa paphewa, ntchafu, matako kapena m'mimba. Masamba a jakisoni ayenera kusinthidwa kuti malo omwewo sawagwiritsanso ntchito mwina kamodzi pamwezi. Ndi subulinaneous ya insulin, chisamaliro chimayenera kumwedwa kuti musalowe m'mitsempha yamagazi pakubaya. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Odwala ayenera kuphunzitsidwa bwino kugwiritsa ntchito insulin yobereka.

Ndondomeko ya insulin makonzedwe ali payekha.

Kukonzekera kwa Humulin® NPH mu mbale

Zisanayambe kugwiritsidwa ntchito, Mbale za Humulin® NPH ziyenera kukulitsidwa kangapo pakati pamafinya mpaka insuliniyo itayambanso kukonzedwa mpaka itakhala yunifolomu yamadzi kapena mkaka. Osagwedezeka mwamphamvu, chifukwa izi zingapangitse mawonekedwe a chithovu, omwe amatha kusokoneza mlingo woyenera.

Musagwiritse ntchito insulini ngati ili ndi mapokoso mukasakaniza. Osagwiritsa ntchito insulin ngati tinthu tating'ono tomwe timamatira pansi kapena makoma a vial, ndikupanga mawonekedwe a frosty.

Gwiritsani ntchito syringe ya insulin yomwe ikufanana ndi kuchuluka kwa insulin.

Ya Humulin® NPH m'makalata

Musanagwiritse ntchito, makatiriji a Humulin® NPH ayenera kugulitsidwa pakati pa manja khumi ndikugwedezeka, kutembenuka kwa 180 ° komanso khumi mpaka insulini itatsitsimuka kwathunthu mpaka itasandulika madzi osungunuka kapena mkaka.Osagwedezeka mwamphamvu, chifukwa izi zingapangitse mawonekedwe a chithovu, omwe amatha kusokoneza mlingo woyenera. Mkati kalikonse kalikonse ndi kakang'ono. mpira wamagalasi omwe amathandizira kusakanikirana kwa insulin. Musagwiritse ntchito insulini ngati ili ndi mapokoso mukasakaniza.

Chida cha cartridge sichimalola kuphatikiza zomwe zili ndi insulin zina mwachindunji mu katiriji palokha: makatiriji sanapangidwire kuti mudzazidwe.

Pamaso pa jekeseni, ndikofunikira kuti mudziwe bwino malangizo a wopanga kuti mugwiritse ntchito cholembera kuti mupeze insulin.

Mankhwala Humulin ®NPH mu syringe yothamanga

Pamaso jakisoni, muyenera kuwerenga Malangizo a QuickPen ™ Syringe pen Instruction.

Hypoglycemia ndizotsatira zoyipa zomwe zimachitika pokhazikitsa kukonzekera kwa insulin, kuphatikiza Humulin ® NPH. Hypoglycemia yamphamvu imatha kutha kwa chikumbumtima ndipo, mwapadera, amafa.

Thupi lawo siligwirizana : Odwala amatha kukumana ndi vuto lodana ndi mtundu wa hyperemia, edema, kapena kuyabwa pamalowo. Izi zimachitika pakatha masiku angapo mpaka milungu ingapo. Nthawi zina, izi zimachitika chifukwa cha zifukwa zosakhudzana ndi insulin, mwachitsanzo, mkwiyo pakhungu ndi wothandizira kuyeretsa kapena jakisoni wosayenera.

Zosagwirizana zimachitika oyambitsa insulin, samachitika kangapo, koma amakhala akulu kwambiri. Amatha kuwonetsedwa ndi kuyabwa kwakukulu, kupuma movutikira, kufupika, kuchepa kwa magazi, kuchuluka kwa mtima, komanso thukuta kwambiri. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pachiwopsezo cha moyo. Nthawi zina mankhwalawa amakumana ndi Humulin® NPH, chithandizo chofunikira chimafunikira. Mungafunike kusintha kwa insulin, kapena kutsimikiza mtima.

Ndi kugwiritsa ntchito nthawi yayitali - chitukuko ndichotheka lipodystrophy pamalo opangira jekeseni.

Milandu ya chitukuko cha edema yadziwika, makamaka ndi kusintha kwachulukidwe ka shuga m'magazi motsutsana ndi maziko a insulin Therapy poyambira osakhutiritsa glycemic control (onani gawo "Maupangiri Apadera").

Mankhwala osokoneza bongo a insulin amachititsa hypoglycemia, limodzi ndi zotsatirazi Zizindikiro : uchidakwa, thukuta kwambiri, tachycardia, kufooka kwa khungu, mutu, kunjenjemera, kusanza, chisokonezo. Nthawi zina, mwachitsanzo, pakhale nthawi yayitali kapena kuwunika kwambiri matenda a shuga, Zizindikiro, zomwe zimayambitsa hypoglycemia zimatha kusintha.

Wofatsa hypoglycemia mutha kuyimitsa pakumeza shuga kapena shuga. Kusintha kwa mlingo wa insulin, zakudya, kapena zolimbitsa thupi kungafunike.

Kuwongolera Hypoglycemia wabwino angathe kuchitidwa ntchito mu mnofu kapena subcutaneous makonzedwe a glucagon, kenako ingestion wa chakudya.

Champhamvu hypoglycemia motsatana ndi chikomokere, kukomoka kapena kupweteka kwamitsempha, kuyimitsidwa ndi kutsekeka / kutsekeka kwa glucagon kapena kulowerera kwamitsempha yokhazikika ya 40% ya dextrose (glucose). Pambuyo pozindikira, wodwalayo ayenera kupatsidwa chakudya chamagulu owonjezera chakudya kuti asayambenso kukhudzana ndi hypoglycemia.

Ngati mukufunika kugwiritsa ntchito mankhwala ena, kuphatikiza insulin, muyenera kufunsa dokotala (onani gawo "Malangizo apadera").

Kuwonjezeka kwa mlingo wa insulini kungafunike poika mankhwala omwe amalimbikitsa kuchuluka kwa shuga m'magazi, monga : kulera kwapakamwa, glucocorticosteroids, mahomoni okhala ndi chithokomiro, beta 2 --adrenomimetics (mwachitsanzo ritodrin, terbutaline), thiazide diuretics, diazoxide, zotumphukira za phenothiazine.

Kuchepetsa kuchuluka kwa insulini kungafunike popereka mankhwala omwe amachepetsa kuchuluka kwa shuga m'magazi, monga : beta-blockers, ndi mankhwala okhala ndi ethanol, mankhwala a anabolic, fenfluramine, guanethidine, tetracyclines, mankhwala a m'kamwa a hypoglycemic, salicylates (mwachitsanzo), mankhwala a sulfanilamide, ma antidepressants (monoamine oxidase inhibitors), angiotensin inhibitors, ndi angiotensin inhibitors Beta-blockers, clonidine, amatha kuphimba mawonetseredwe a zizindikiro za hypoglycemia.

Zotsatira zakusakanikirana kwa insulin yaumunthu ndi insulin yakuchokera kwa nyama kapena insulin ya anthu yopangidwa ndi ena omwe sanaphunzire.

Kusamutsa wodwala kupita ku mtundu wina kapena kukonzekera kwa insulin ndi dzina lina lamalonda kuyenera kuchitika moyang'aniridwa ndi achipatala. Kusintha kwa ntchito, mtundu (wopanga), mtundu (Wokhazikika, NPH, ndi zina) zamtundu (nyama, munthu, insulin analogs) ndi / kapena njira yopanga (DNA recombinant insulin kapena insulini yachikhalidwe) ingafune kusintha kwa mlingo.

mwachitsanzo, chifukwa cha insulin Therapy, zonse kapena zizindikiro zina zakutsogolo kwa hypoglycemia zimatha, zomwe odwala ayenera kudziwitsidwa. Zizindikiro zakutsogolo kwa hypoglycemia zimatha kusintha kapena kusalankhula pang'ono ndi njira yayitali ya matenda a shuga, matenda ashuga a m'mimba, kapena chithandizo chamankhwala monga beta-blockers.

Mlingo wosakwanira kapena kusiya kulandira chithandizo, makamaka kwa odwala omwe ali ndi vuto la matenda ashuga 1, kungayambitse matenda a hyperglycemia ndi matenda ashuga a ketoacidosis (mikhalidwe yomwe ikhoza kukhala yowopsa kwa wodwalayo).

Kufunika kwa insulini kumatha kuchepa ndi kusakwanira kwa adrenal gland, gland planditary kapena chithokomiro, ndi aimpso kapena kwa chiwindi. Ndi matenda ena kapena kupsinjika kwamalingaliro, kufunikira kwa insulin kungakulitse. Kuwongolera mlingo wa insulin kungafunikenso ndi kuwonjezeka kwa zochitika zolimbitsa thupi kapena kusintha kwa zakudya zomwe mumakonda.

Mukamagwiritsa ntchito insulin pokonzekera limodzi ndi mankhwala a gulu la thiazolidinedione, chiopsezo chotenga matenda a edema ndi matenda a mtima omwe amalephera chikuwonjezereka, makamaka kwa odwala omwe ali ndi matenda amtima komanso kupezeka kwa zinthu zomwe zingayambitse matenda osalephera a mtima.

QUICKPEN ™ SYRINGE HANDLES

Humulin® Regular QuickPen ™,Humulin® NPH QuickPen ™,Humulin® M3 QuickPen ™

MALANGIZO OTHANDIZA MALO OTSATIRA

CESANI LERANI ZINSINSI izi ASANAYITSE

Quick Pen Syringe chole ndi yosavuta kugwiritsa ntchito. Ndi chipangizo chothandizira kuperekera insulin (cholembera insulini cholembera) yomwe ili ndi 3 ml (ma 300) pakukonzekera kwa insulin ndi ntchito ya 100 IU / ml. Mutha kubaya kuchokera 1 mpaka 60 magawo a insulin pa jakisoni. Mutha kukhazikitsa mlingo molondola ndi umodzi. Ngati mwayika mayunitsi ambiri. Mutha kukonza mankhwalawa osataya insulin.

Musanagwiritse ntchito syPinge ya QuickPen, werengani bukuli ndikutsatira malangizo ake ndendende.Ngati simutsatira malangizowa, mutha kulandira inshuwaransi yotsika kwambiri kapena kwambiri.

Penti ya QuickPen Syringe ya insulin iyenera kugwiritsidwa ntchito ndi inu nokha. Osadutsa cholembera kapena singano kwa ena, chifukwa zimatha kufalitsa kachilomboka. Gwiritsani ntchito singano yatsopano jekeseni iliyonse.

Musagwiritse ntchito cholembera ngati gawo lake lina lowonongeka kapena laphwanyika. Nthawi zonse tengani cholembera chopanda kanthu ngati mungataye cholembera kapena chikaonongeka.

Kukonzekera Kwachangu kwa Syninge

Werengani ndikutsatira malangizo ogwiritsira ntchito mankhwalawa.

Onani cholembera pa cholembera asanalowe jakisoni iliyonse kuti muwonetsetse kuti tsiku lakelo linatha ndipo mukugwiritsa ntchito mtundu woyenera wa insulini, musachotse chizindikiro pa cholembera.

Zindikirani Mtundu wa batani lotulutsa mwachangu cholembera wa syringe wa QuickPen umafanana ndi mtundu wa Mzere pa cholembera cholembera ndipo zimatengera mtundu wa insulin. Mbukuli, batani la imvi limadukaduka. Mtundu wa beige wa cholembera cha syringe wa QuickPen umawonetsera kuti umapangidwa kuti ugwiritse ntchito ndi zinthu za Humulin.

Dokotala wanu wakupangira mtundu wa insulin wabwino kwambiri. Kusintha kulikonse kwa mankhwala a insulin kuyenera kuchitidwa kokha moyang'aniridwa ndi dokotala.

Musanagwiritse ntchito cholembera, onetsetsani kuti singanoyo imalumikizidwa kwathunthu ndi cholembera.

Tsatirani malangizo omwe aperekedwa apa.

Mafunso omwe amafunsidwa pafupipafupi okonzekera kukonzekera Penti ya QuickPen Syringe kuti mugwiritse ntchito

- Kodi kukonzekera kwanga kwa insulin kuyenera kuwoneka bwanji? Kukonzekera kwina kwa insulin ndi kuyimitsidwa kogwiritsa, pomwe ena ndi mayankho omveka, onetsetsani kuti mukuwerenga malongosoledwe a insulin m'mawu omwe aikidwa kuti mugwiritse ntchito.

- Ndichite chiyani ngati mlingo wanga waposa 60? Ngati mlingo womwe wakupatsani uli pamwamba pa mayunitsi 60, mufunika jekeseni wachiwiri, kapena mutha kulankhulana ndi dokotala za nkhaniyi.

- Chifukwa chiyani ndigwiritse ntchito singano yatsopano kubayira iliyonse? Ngati singano agwiritsidwanso ntchito, mutha kulandira mulingo wolakwika wa insulin, singano imatha kutsekeka, kapena cholembera sichingathe, kapena mutha kutenga kachilomboka chifukwa chazovuta.

- Ndichite chiyani ngati sinditsimikiza kuchuluka kwa insulini yanga ? Kwezani chogwirira kuti nsonga ya singano ilowe pansi. Mulingo wapa cartridge wosonyeza bwino kuchuluka kwa insulini yotsalira. Manambalawa ASATHA kugwiritsidwa ntchito kukhazikitsa mlingo.

"Ndichite chiyani ngati sindingathe kuchotsa cholembera ku cholembera?" Kuti muchotse chipewa, kokerani. Ngati mukuvutikira kuchotsa chipewa, sinthani mosamala kachulukidwe kake ndi kuyerekezera kuti mumasule, ndiye kuti mukoka kuti muchotse kapuyo.

Kuyang'ana cholembera cha SyPinge cha QuickPen cha Insulin

Onani kuchuluka kwanu kwa insulin nthawi zonse. Chitsimikizo cha kutulutsidwa kwa insulini kuchokera ku cholembera kuti chichitike jekeseni iliyonse isanafike pang'onopang'ono mpaka inshuwaransi ikawonekere kuonetsetsa kuti cholembera chakonzeka.

Ngati simukuyang'ana insulin yanu musanayambe kudwala, mutha kulandira insulin yochepa kwambiri kapena yambiri.

Mafunso Omwe Amakonda Kufunsa za Kuchita Macheke a Insulin

- Chifukwa chiyani ndiyenera kuwerengera insulin yanga isanadye jakisoni iliyonse?

1. Izi zikuwonetsetsa kuti cholembera chakonzekera kumwa.

2. Izi zikutsimikizira kuti chinyengo cha insulin chimatuluka mu singano mukakanikiza batani la mlingo.

3. Izi zimachotsa mpweya womwe ungatenge mu singano kapena katoni ya insulini pakagwiritsidwe ntchito.

- Ndiyenera kuchita chiyani ngati sindingathe kukanikiza bwino batani la mlingo panthawi yachangu ya insulin?

1. Phatikizani singano yatsopano.

2. Yang'anani insulin kuchokera ku cholembera.

"Ndichitenji ndikawona makamu am'kati mwa katiriji?"

Muyenera kufufuza insulin kuchokera ku cholembera. Kumbukirani kuti simungasunge cholembera ndi singano yolumikizidwa, chifukwa izi zimatha kupangitsa kuti pakhale thovu. Khungu laling'ono la mpweya silikuwakhudza mankhwalawo, ndipo mutha kulowa muyezo wanu mwachizolowezi.

Kukhazikitsidwa kwa mlingo wofunikira

Tsatirani malamulo a asepsis ndi antiseptics omwe adokotala amuuzani.

Onetsetsani kuti mwalowa muyezo wofunikira mwa kukanikiza ndikuyika batani la mlingo ndikuwerengera pang'onopang'ono mpaka 5 musanachotsere singano. Ngati insulin ikudontha kuchokera singano, mwina simunagwire singano pansi pa khungu lanu nthawi yayitali.

Kukhala ndi dontho la insulin pamsana pa singano ndikwabwinobwino. Izi sizingakhudze mlingo wanu.

Cholembera cha syringe sichingakulolezeni kujambula mlingo wopitilira muyeso wamagulu a insulin otsalira mu katoni.

Ngati mukukayika kuti mwapereka mlingo wonse, musamaperekenso mlingo wina. Imbani woimira wanu wa Lilly kapena dokotala wanu kuti akuthandizeni.

Ngati mlingo wanu uposa kuchuluka kwa zigawo zomwe zatsalira mu cartridge, mutha kuyika kuchuluka kwa insulini mu cholembera ichi ndipo mugwiritse ntchito cholembera chatsopano kuti mumalize muyeso wofunikira, Pena lembani mlingo wonse pogwiritsa ntchito cholembera chatsopano.

Osayesa kubaya insulin potembenuza batani la mlingo. Simulandila insulin ngati mutembenuza batani la mlingo. Muyenera kusinthitsa batani la mlingo molunjika kuti mulandire mlingo wa insulin.

Musayese kusintha mlingo wa insulin panthawi ya jakisoni.

Singano yomwe imagwiritsidwa ntchito iyenera kutayidwa malinga ndi zofunikira zotaya zinyalala zakuchipatala.

Chotsani singano pambuyo pa jekeseni iliyonse.

Mafunso Ofunsidwa Kawirikawiri

- Chifukwa chovuta kukanikiza batani la mlingo, ndikuyesera liti kubaya?

1. Singano yanu itha kumangidwa. Yesani kuphatikiza singano yatsopano. Mukachita izi, mutha kuwona momwe insulin imatuluka mu singano. Kenako yang'anani cholembera.

2. Makina osindikiza mwachangu pa batani la mlingo amatha kupangitsa batani kukanikiza. Kutsinikiza pang'onopang'ono batani la mlingo kungapangitse kukanikiza mosavuta.

3. Kugwiritsa ntchito singano yayikulu kukuthandizira kuti musakanize kubatani.

Funsani othandizira anu azaumoyo za kukula kwaku singano kopambana.

4. Ngati kukanikiza batani mukamapereka mankhwalawo kumakhalabe kolimba mukamaliza mfundo zonse pamwambapa, cholembera cha syringe chiyenera kulowedwa.

- Ndiyenera kuchita chiyani ngati syringe yachala ya Peneni ikagwiritsidwa ntchito?

Cholembera chako chidzakhala cholimba ngati nkovuta kuti ugwiritse kapena kubayira. Popewa cholembera kuti chisamatirire:

1. Phatikizani singano yatsopano. Mukachita izi, mutha kuwona momwe insulin imatuluka mu singano.

2. Chongani insulin.

3. Ikani mlingo wofunikira ndi jakisoni.

Musayesere kupaka cholembera, chifukwa izi zitha kuwononga gawo la cholembera.

Kukanikiza batani la mlingo kumatha kulowa ngati zinthu zakunja (dothi, fumbi, chakudya, insulini kapena zakumwa zilizonse) zikalowa mkatikati mwa syringe. Musalole zodetsa kuti zilowe mu cholembera.

- Chifukwa chiyani insulini imatuluka mu singano nditamaliza kupereka mlingo wanga?

Mwina mwachotsa singano mwachangu kwambiri pakhungu.

1. Onetsetsani kuti mukuwona nambala ya "0" pazenera la chisonyezo.

2.Kupereka mlingo wotsatira, kanikizani ndikuyika batani la mlingo ndikuyamba pang'ono pang'ono mpaka 5 musanachotsere singano.

- Ndichitenji ngati mlingo wanga wakhazikitsidwa, ndipo batani loyamwa mwangozi limakhala kuti limakonzanso mkati popanda singano yolumikizidwa ndi syringe?

1. Sinthani batani la mlingo kukhala zero.

2. Phatikizani singano yatsopano.

3. Chitani insulin.

4. Ikani mlingo ndi jakisoni.

"Ndingatani ngati nditayamwa mlingo woyenera (wotsika kwambiri kapena wotsika kwambiri)?" Sinthani batani la mlingo kumbuyo kapena kutsogolo kuti mukonze uthengawo.

- Ndichite chiyani ngati nditha kuwona kuti insulini ikutuluka mu singano ya singano pakusankha kwa mankhwala kapena kusintha? Musamapereke mlingo, chifukwa mwina simungalandire mlingo wathunthu. Khazikitsani cholembera ku nambala ya zero ndikuyang'ananso kuchuluka kwa insulini kuchokera ku cholembera (onani gawo "Kuyang'ana Pangongole Yotumizira Ya QuickPen Kuti Ipatsidwe Insulini"). Khazikitsani mlingo woyenera ndi jakisoni.

- Ndichite chiyani ngati kumwa kwathunthu sikukwaniritsidwa? Cholembera sichingakulorengenso kuti muike mankhwalawo mopitilira kuchuluka kwa kuchuluka kwa insulini yotsalira mukatoni. Mwachitsanzo, ngati mukufuna mayunitsi 31, ndipo magawo 25 okha atsala mu katoni, ndiye kuti simungathe kudutsa nambala 25 mukamayikiratu. Osayesa kukhazikitsa mlingowo podutsa nambala iyi. Ngati gawo loyenera latsala m'khola, mutha:

1. Lowetsani gawo ili, kenaka lembani mlingo wotsalira pogwiritsa ntchito cholembera chatsopano, kapena

2. Lowetsani mlingo wathunthu kuchokera ku cholembera chatsopano.

- Chifukwa chiyani sindingathe kukhazikitsa mlingo kuti mugwiritse ntchito insulin yaying'ono yomwe yasiyidwa mu katiriji yanga? Cholembera chimbalecho chimapangidwa kuti chilolere kuyamwa kwa magawo 300 a insulin. Chida cha cholembera sichitha kuteteza katiriji kuti lisatheretu, chifukwa kuchuluka kwa insulini komwe kumakhalabe ndi kathumba sikungavulazidwe ndikulondola.

Kusunga ndi kutaya

Cholembera sichingagwiritsidwe ntchito ngati chakhala kunja kwa firiji kwa nthawi yopitilira nthawi yomwe idafotokozedwa mu Maupangiri Ogwiritsira Ntchito.

Osasunga cholembera ndi singano yake. Ngati singano yatsala kuti ikanikizidwe, insulin ingatuluke m'timalo, kapena insulini itha kuwuma mkati mwa singano, ndikupangitsa kuti singano iduke, kapena kuti thovu la mpweya lithe mkati mwa cartridge.

Zilembera zomwe sizikugwiritsidwa ntchito ziyenera kusungidwa mufiriji kutentha kwa 2 ° C mpaka 8 ° C. Osagwiritsa ntchito cholembera kuti chitauma.

Cholembera cha syringe chomwe mukugwiritsa ntchito pano chiyenera kusungidwa pa kutentha osaposa 30 ° C komanso pamalo otetezedwa kuti asatenthe ndi kutentha.

Fotokozerani Malangizowo kuti mugwiritse ntchito pozindikira bwino malo osungirako cholembera.

Sungani cholembera kuti chisafike kwa ana.

Taya singano zogwiritsidwa ntchito polemba-maumboni, zopangira zofananira (mwachitsanzo, zotengera zama biohazardous zvinhu kapena zinyalala), kapena monga momwe katswiri wanu wazachipatala adakulimbikitsira.

Taya zolembera zomwe mugwiritse ntchito singano popanda singano zophatikizidwa kwa iwo komanso mogwirizana ndi malingaliro a dokotala.

Osabwezanso zotengera zazitali.

Funsani dokotala wanu za momwe mungathere kutaya zotengera zotayidwa m'dera lanu.

Humulin® ndi Humulin® mu QuickPen ™ Syringe pen ndizizindikiro za Eli Lilly & Company.

QuickPen ™ Syringe pen imakwaniritsa zofunikira zenizeni za dosing ndi zofunikira za ISO 11608-1: 2000

Onetsetsani kuti muli ndi zinthu zotsatirazi:

□ Kuthamangitsa Pen Syringe

□ Chingwe chatsopano cha cholembera

□ Swab wothira mowa

Zophatikizira ndi Zingwe za QuickPen Syringe * onani chithunzi 3 .

Kukongoletsa Mtundu wa Dzu Lobatani - onani chithunzi 2 .

Kugwiritsa ntchito cholembera

Tsatirani malangizo awa kuti mumalize jakisoni aliyense.

1. Kukonzekera kwa Syninge Yachangu

Kokani kapu ya cholembera kuti muchotse. Osazungulira kapu. Osachotsa cholembera ku cholembera.

Onetsetsani kuti mwayang'ana insulini yanu:

Tsiku lotha ntchito

Chidwi: Nthawi zonse werengani cholembera cholembera kuti onetsetsani kuti mukugwiritsa ntchito mtundu woyenera wa insulin.

Kwa kuyimitsidwa kwa insulin kokha:

Lungunulani cholembera maulendo 10 pakati pama manja anu

tembenuza cholembera maulendo 10.

Kusakaniza ndikofunikira kuti mukhale otsimikiza kuti mupeze mlingo woyenera. Insulin iyenera kuwoneka yosakanikirana.

Tengani singano yatsopano.

Chotsani chomata papepala ndi singano yakunja.

Gwiritsani ntchito swab wothira mowa kuti mupukutire disc ya mphira kumapeto kwa cholembera.

Valani singano mu cap kulondola pamphepete mwa cholembera.

Skani pa singano kufikira mutalumikizidwa kwathunthu.

2. Kuyang'ana cholembera cha QuickPen Syringe cholembera Insulin

Chenjezo: Ngati simukuyang'ana insulin musanadye jakisoni iliyonse, mutha kutsika kwambiri kapena kutsika kwambiri ndi insulin.

Chotsani singano yakunja. Osataya.

Chotsani thumba lamkati la singano ndikuitaya.

Khazikitsani magulu awiri mutembenuza batani la mlingo.

Lowetsani cholembera.

Dinani pazosungira cartridge kuti mulole mpweya kuti utuluke

Ndi singano ikuloza, kanikizani batani la mlingo mpaka litayime ndipo nambala ya "0" ipezekere pazenera.

Gwiritsani ntchito batani la muyeso poti mwaweleranso ndipo muwerenge pang'onopang'ono mpaka 5.

Kutsimikizira kwa insulin kudya kumawerengedwa ngati kumalizidwa kwa insulin kumapeto kwa singano.

Ngati phula la insulin silikuwoneka kumapeto kwa singano, ndiye kuti mubwereze njira zinayi za insulin, kuyambira pa 2B ndikumaliza ndi point 2G.

Chidziwitso: Ngati simukuwona kupsinjika kwa insulin ikuwoneka kuchokera ku singano, ndikuyika mankhwalawo kumakhala kovuta, ndiye kuti m'malo mwa singanoyo ndikubwereza kuyang'ana kuchuluka kwa insulini kuchokera mu cholembera.

Sinthani batani la mlingo kuti mupeze chiwerengero chomwe mukufuna jakisoni.

Ngati mwayika magulu ambiri mwangozi, mutha kuwongolera uthengawo mosinthanitsa ndi batani lolowanalo.

Ikani singano pansi pa khungu pogwiritsa ntchito jakisoni yemwe dokotala wanu wakupatsani.

Ikani chala chanu pa batani la mlingo ndikulimbikira batani la mlingo mpaka litayima kwathunthu.

Kuti mulowetse mlingo wathunthu, gwiritsani batani la mlingo ndikuwerengerani pang'onopang'ono mpaka 5.

Chotsani singano pansi pa khungu.

Zindikirani : Yang'anani ndikuonetsetsa kuti mukuwona nambala ya "0" pazenera la dokotala, kuti muwonetsetse kuti mwalowa muyezo wonse.

Ikani chotseka chakunja pa singano.

Chidziwitso: Chotsani singano pambuyo pa jekeseni aliyense kuti muchepetse thovu m'malembedwe.

Osasunga cholembera ndi singano yake.

Tulutsani singano ndi chophimba chakunja ndikuitaya mogwirizana ndi malangizo a dokotala.

Ikani chipewa pa syringe cholembera, chikugwirizana ndi cholumikizira cap ndi chisonyezo cha mlingo pokankhira cap mwachindunji mu axis pa cholembera.

Kuwonetsa magawo 10 (onani chithunzi 4) .

Ngakhale manambala amasindikizidwa pazenera la manambala kuti manambala, manambala osamvetseka amasindikizidwa ngati mizere yolunjika pakati pa manambala.

Chidziwitso: Cholembera sichingakuloreni kukhazikitsa kuchuluka kwa mayunitsi mopitilira kuchuluka kwa zigawo zomwe zatsala mu cholembera.

Ngati mulibe chitsimikizo kuti mwapereka mlingo wonse, musamaperekenso mankhwala ena.

Kukopa pa kuthekera kuyendetsa ma transp. Wed Ndi ubweya:

Pa hypoglycemia, wodwalayo amatha kuchepa ndende komanso kuthamanga kwa zochitika zama psychomotor. Izi zitha kukhala zowopsa nthawi zomwe maluso amenewa amafunikira makamaka (mwachitsanzo, kuyendetsa magalimoto kapena makina ogwiritsa ntchito).

Odwala ayenera kulangizidwa kuti azisamala popewa hypoglycemia poyendetsa magalimoto. Izi ndizofunikira kwambiri kwa odwala omwe ali ndi zofatsa kapena zosapezekapo zizindikiro, okhazikika a hypoglycemia kapena okhazikika a hypoglycemia. Zikatero, adotolo amayenera kuwunika momwe magalimoto amayendera.

Kuyimitsidwa kwa kayendetsedwe ka subcutaneous, 100 IU / ml.

10 ml ya mankhwalawa osalowa mugalasi Mbale. Botolo 1 limodzi ndi malangizo ogwiritsira ntchito mankhwalawa amaikidwa pakatoni.

3 ml pa katoni imodzi yagalasi losalowerera. Makatoni asanu amayikidwa mu chithuza. Chithuza chimodzi limodzi ndi malangizo ogwiritsira ntchito zimayikidwa pakatoni.

Kapenanso bokosilo limakhazikika mu cholembera cha QuickPen tm. Ma syringe asanu pamodzi ndi malangizo ogwiritsira ntchito ndi malangizo ogwiritsira ntchito cholembera amaphatikizidwa mukatoni.

Kutentha kwa 2 mpaka 8 ° C. Kuteteza ku dzuwa mwachindunji ndi kutentha. Osalola kuzizira.

Chithandizo chachiwiri Sungani kutentha kwa chipinda - kuyambira 15 mpaka 25 ° C osaposa masiku 28.

Pewani kufikira ana.

Osagwiritsa ntchito tsiku lanu litatha.

Zoyenera kugawidwa kuchokera ku malo ogulitsa mankhwala: Nambala Yalembetsa

Dzina la malonda akukonzekera:
HUMULIN ® NPH

Dzinalo Losagwirizana Ndi Mayiko Onse (INN):
Isulin Insulin (Umisiri wa Majini a Anthu)

Mlingo
Kuyimitsidwa kwa makina oyang'anira

Kufotokozera:
Kuyimitsidwa koyera komwe kumachoka, ndikupanga koyera koyera komanso kowoneka bwino, kopanda mtundu kapena pafupifupi wamitundu. Mtengo umasinthidwa mosavuta ndikugwedezeka modekha.

Gulu la Pharmacotherapeutic
Hypoglycemic wothandizila - sing'anga-insulin.

Nambala ya ATX A10AC01.

Mankhwala
Mankhwala
Humulin ® NPH ndi insulin yothandizanso anthu. Chochita chachikulu cha insulin ndi kuphatikiza shuga kagayidwe. Kuphatikiza apo, imakhala ndi anabolic komanso anti-catabolic zotsatira zake zosiyanasiyana zamthupi. Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa ma amino acid, koma nthawi yomweyo kumachepa mu glycogenolysis, gluconeogeneis, ketogenesis, lipolysis, proteinabolism ndi kutulutsidwa kwa ma amino acid.
Humulin NPH ndi insulin yomwe ikukonzekera. Kukhazikika kwa mankhwala ndi ola limodzi pambuyo pa kukonzekera, mphamvu yayikulu imakhala pakati pa maola awiri ndi asanu ndi atatu, kutalika kwa nthawi ndi maola 18-20. Kusiyana kwamwini pantchito ya insulin kumadalira zinthu monga mlingo, kusankha jakisoni, malo olimbitsa thupi, ndi zina zambiri.

Pharmacokinetics
Kukwanira kwathunthu ndi kuyambika kwa mphamvu ya insulin kumadalira malo a jakisoni (m'mimba, ntchafu, matako), mlingo (kuchuluka kwa insulin), kuchuluka kwa insulini mu mankhwalawa, ndi zina. Amawonongedwa ndi insulinase makamaka m'chiwindi ndi impso. Amachotsa impso (30-80%).

Zizindikiro zogwiritsidwa ntchito

Matenda a shuga odwala matenda a insulin.

Mimba mwa odwala matenda ashuga. Contraindication

Hypersensitivity kupita ku insulin kapena chimodzi mwazinthu za mankhwala.

Hypoglycemia. Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere
Pakati pa nthawi yayitali, ndikofunikira kuti pakhale chitetezo chabwino kwa odwala omwe amalandila insulin (omwe amadalira matenda a insulin kapena matenda a shuga). Kufunika kwa insulin nthawi zambiri kumachepetsa panthawi yoyambirira ndikuwonjezeka panthawi yachiwiri komanso yachitatu. Nthawi yobadwa pambuyo pokhapokha ndipo mwayamba kubadwa, zofunika za insulin zimatha kugwa kwambiri. Odwala omwe ali ndi matenda ashuga amalangizidwa kuti azidziwitse dokotala wawo za kubereka kapena kukonzekera pakati. Odwala omwe ali ndi matenda a shuga mellitus nthawi yoyamwitsa angafunikire kusintha mlingo wa insulin, zakudya, kapena zonse ziwiri. Mlingo ndi makonzedwe
Mlingo wa Humulin ® NPH umatsimikiziridwa ndi dokotala aliyense payekha, kutengera mlingo wa glycemia. Mankhwalawa amayenera kuperekedwa mosavuta. Intramuscular management ndiyothekanso. Intravenous ya mankhwala Humulin ® NPH amatsutsana.
Kutentha kwa mankhwala omwe amaperekedwa kuyenera kukhala kutentha kwambiri. Jakisoni wotsekemera ayenera kuperekedwa kwa phewa, ntchafu, matako kapena pamimba. Masamba a jakisoni ayenera kusinthidwa kuti malo omwewo sawagwiritsanso ntchito mwina kamodzi pamwezi. Ndi subulinaneous ya insulin, chisamaliro chimayenera kumwedwa kuti musalowe m'mitsempha yamagazi pakubaya. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Odwala ayenera kuphunzitsidwa bwino kugwiritsa ntchito insulin yobereka. Ndondomeko ya insulin makonzedwe ali payekha. Kukonzekera mawu oyamba
Musanagwiritse ntchito, makatiriji a Humulin ® NPH ayenera kugulitsidwa pakati pa manja khumi ndikugwedezeka, kutembenuka ndi 180 ° mpaka kakhumi mpaka insulini itayambidwenso mpaka itakhala yodzaza madzi kapena mkaka. Osagwedezeka mwamphamvu, chifukwa izi zingapangitse mawonekedwe a chithovu, omwe amatha kusokoneza mlingo woyenera. Mkati mwa bokosi lirilonse pali galasi yaying'ono yagalasi yomwe imathandizira kusakanikirana kwa insulin. Musagwiritse ntchito insulini ngati ili ndi mapokoso mukasakaniza.
Chipangizo cha ma cartridge sichimalola kusakanikirana ndi zomwe zili ndi insulini zina mwachindunji mu cartridge lokha. Makatoniwo sanapangidwe kuti adzazitsidwe.
Pamaso pa jekeseni, ndikofunikira kudziwa bwino zomwe wopanga amagwiritsa ntchito cholembera-jakisoni wa insulin. Zotsatira zoyipa
Hypoglycemia ndizotsatira zoyipa zomwe zimachitika pokhazikitsa kukonzekera kwa insulin, kuphatikiza Humulin ® NPH. Hypoglycemia yamphamvu imatha kutha kwa chikumbumtima ndipo, mwapadera, amafa.
Zotsatira zoyipa: Odwala amatha kudwala matendawa m'njira yofiyira, kutupa, kapena kuyabwa pamalowo. Izi zimachitika pakatha masiku angapo mpaka milungu ingapo. Nthawi zina, izi zimachitika chifukwa cha zifukwa zosakhudzana ndi insulin, mwachitsanzo, mkwiyo pakhungu ndi wothandizira kuyeretsa kapena jakisoni wosayenera.
Zotsatira zoyipa zamagetsi, oyambitsidwa ndi insulin, samachitika kangapo, koma amakula kwambiri. Amatha kuwonetsedwa ndi kuyabwa kwakukulu, kupuma movutikira, kufupika, kuchepa kwa magazi, kuchuluka kwa mtima, komanso thukuta kwambiri. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pachiwopsezo cha moyo. Nthawi zina mankhwalawa amakumana ndi Humulin ® NPH, chithandizo chofunikira chimafunikira. Mungafunike kusintha kwa insulin, kapena kutsimikiza mtima.
Ndi kugwiritsa ntchito nthawi yayitali - chitukuko ndichotheka lipodystrophy pamalo opangira jekeseni. Bongo
Mankhwala osokoneza bongo ochuluka a insulin amayambitsa hypoglycemia, limodzi ndi zizindikiro zotsatirazi: ulesi, thukuta kwambiri, tachycardia, kufooka kwa khungu, kupweteka mutu, kunjenjemera, kusanza, chisokonezo.Mwachitsanzo, nthawi zina kapena kuwunika kovuta kwa matenda a shuga, Zizindikiro za ma harbinger a hypoglycemia zimatha kusintha.
Hypoglycemia wofatsa nthawi zambiri imatha kuimitsidwa mwa kumeza shuga kapena shuga. Kusintha kwa mlingo wa insulin, zakudya, kapena zolimbitsa thupi kungafunike. Malangizo a hypoglycemia wolimbitsa amatha kuchitika pogwiritsa ntchito minyewa kapena subcutaneous makukidwe a glucagon, otsatiridwa ndi kumeza chakudya. Miyezo yambiri ya hypoglycemia, yokhala ndi chikomokere, kukomoka kapena kuchepa kwa mitsempha, imayimitsidwa ndi kutsekeka / kupindika kwa glugagon kapena kulowetsedwa kwa njira yokhazikika ya shuga. Pambuyo pozindikira, wodwalayo ayenera kupatsidwa chakudya chamagulu owonjezera chakudya kuti asayambenso kukhudzana ndi hypoglycemia. Kuchita ndi mankhwala ena
Kuchulukitsa kwa kuchuluka kwa insulin kungafunike ngati mankhwala omwe amachepetsa shuga a magazi atchulidwa, monga njira zakulera za pakamwa, glucocorticosteroids, mahomoni a chithokomiro, danazol, beta 2 - adrenomimetics (mwachitsanzo, ritodrin, salbutamol, terbutaline), thiazide diuretics, chlorprotix isoniazid, lithiamu carbonate, nikotini acid, zotumphukira za phenothiazine. Kuchepetsa mulingo wa insulin kungafunike ngati mankhwalawa amachepetsa magazi a shuga, monga mankhwala a beta-blockers, ethanol ndi ethanol, mankhwala a anabolic, ma fenfluramine, guanethidine, ma tetracyclines, mankhwala a hypoglycemic, salicylates (mwachitsanzo, acetylsalicylic acid). , antidepressants (monoamine oxidase inhibitors), angiotensin otembenuza enzyme inhibitors (Captopril, enapril), octreotide, angiotensin receptor antagonists Nzina II.
Beta-blockers, clonidine, reserpine amatha kuphimba mawonetseredwe a zizindikiro za hypoglycemia.
Kusagwirizana . Zotsatira zakusakanikirana kwa insulin ya anthu ndi insulin ya nyama kapena insulin ya anthu yopangidwa ndi ena omwe sanaphunzire. Malangizo apadera
Kusamutsa wodwala kupita ku mtundu wina kapena kukonzekera kwa insulin ndi dzina lina lamalonda kuyenera kuchitika moyang'aniridwa ndi achipatala. Zosintha muzochitika za mtundu (wopanga), mtundu (Wokhazikika, MOH, insulini wa zochokera kuzinyama) zitha kubweretsa kufunika kokonza mlingo.
Kwa odwala ena, kusintha kwa mlingo kumakhala kofunikira pakusintha kuchokera ku insulin yochokera ku nyama kupita ku insulin ya anthu. Izi zitha kuchitika kale poyambilira kukonzekera kwa insulin ya anthu kapena pang'onopang'ono pakangotha milungu ingapo kapena miyezi ingapo atasamutsidwa.
Zizindikiro - zotsogola za hypoglycemia pa nthawi ya makulidwe a insulin m'magazi ena amalephera kutchulidwa kapena kusiyanasiyana ndi zomwe zimawonedwa pa insulin ya nyama. - oyambitsa matenda a hypoglycemia, omwe odwala ayenera kudziwitsidwa. Zizindikiro - zotsogola za hypoglycemia zingasinthe kapena kusalankhula pang'ono ndi matenda a shuga, matenda a shuga wodwala wowopseza moyo).
Kufunika kwa insulini kumatha kuchepa ndi kusakwanira kwa adrenal gland ya pituitary kapena chithokomiro cha chithokomiro, ndi aimpso kapena hepatic insuffential M'matenda ena kapena mukumva kupsinjika kwamalingaliro, kufunika kwa insulini kungakuluke.Kuwongolera mlingo wa insulin kungafunikenso ndi kuwonjezeka kwa zochitika zolimbitsa thupi kapena kusintha kwa zakudya zomwe mumakonda. Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu
Pa hypoglycemia, wodwalayo amatha kuchepa ndende komanso kuthamanga kwa zochitika zama psychomotor. Izi zitha kukhala zowopsa nthawi zomwe maluso amenewa amafunikira makamaka (mwachitsanzo, kuyendetsa galimoto kapena makina ogwiritsa ntchito).
Odwala ayenera kulangizidwa kuti azisamala kuti asamayendetse hypoglycemia poyendetsa. Izi ndizofunikira kwambiri kwa odwala omwe ali ndi zofowoka kapena zosapezekapo - zotsogola za hypoglycemia kapena kukula pafupipafupi kwa hypoglycemia. Zikatero, adotolo amayenera kuwunika momwe wodwala angayendetsere galimoto. Mankhwala
Kutulutsa Fomu
Kuyimitsidwa kwa subcutaneous makonzedwe a 100 IU / ml mu makilogalamu atatu a 3 ml. Makatoni 5 pazinthu zilizonse za PVC / aluminium zojambulazo. Chithuza chimodzi limodzi ndi malangizo ogwiritsira ntchito zimayikidwa pakatoni.
Malo osungira
Sungani pa 2 ° -8 ° C m'malo osavomerezeka ndi ana. Kuteteza ku dzuwa mwachindunji ndi kutentha. Osalola kuzizira. Mankhwala omwe amagwiritsidwa ntchito mu 3 ml ya cartridge iyenera kusungidwa kutentha kutentha kwa 15 ° -25 ° C osapitirira masiku 28.
Mndandanda B. Kwa mankhwala omwe ali mu syringe pensulo:
Kutulutsa Fomu
Kuyimitsidwa kwa subcutaneous makonzedwe a 100 IU / ml mu cholembera cha 3 ml. Ma syringe asanu mu pepala la pulasitiki limodzi ndi malangizo ogwiritsira ntchito mankhwalawa ndipo malangizo ogwiritsira ntchito cholembera amayikidwa m'bokosi.
Malo osungira
Sungani kutentha kwa 2-8 ° C m'malo osavomerezeka ndi ana. Kuteteza ku dzuwa mwachindunji ndi kutentha. Osalola kuzizira. Mankhwala ogwiritsira ntchito cholembera cha 3 ml ayenera kusungidwa kutentha 15-25 ° C osaposa masiku 28.
Mndandanda B. Tsiku lotha ntchito
Zaka zitatu
Osagwiritsa ntchito tsiku lanu litatha. Mankhwala Okhala Pamalo a Pharmacy
Ndi mankhwala. Dzina ndi adilesi yaopanga
"Lilly France S.A.S.", France
"Lilly France S.A.S." Rue du Colonel Lilly, 67640 Fegersheim, France
"Lilly France S.A.S." Py do Colonel Lilly, 67640 Fegersheim, France Zoyimira ku Russia:
Eli Lilly Vostok S.A., 123317, Moscow
Krasnopresnenskaya embankment, 18

Kuyenda mthupi.

Mwa zina, chinthu ichi chimadziwika ndi zotsatira za anabolic komanso anti-catabolic pazinthu zina za thupi. M'matumba, mumakhala kuchuluka kwa glycogen, mafuta acid, glycerol, komanso kuchuluka kwa mapuloteni komanso kuchuluka kwa amino acid.

Komabe, kuchepetsa glycogenolysis, gluconeogeneis, lipolysis, mapuloteni catabolism komanso kumasulidwa kwa amino acid kumatha kuyambika. Nkhaniyi ikufotokoza mwatsatanetsatane mankhwala omwe amalowa m'malo mwa ma pancreatic hormone omwe amatchedwa Humulin, ma analogues omwe amatha kupezekanso pano.

Humulin ndimakonzedwe a insulin ofanana ndi anthu, omwe amadziwika nthawi yayitali.

Monga lamulo, kuyambika kwa vuto lake kumawonekera mphindi 60 pambuyo pa kuwongolera mwachindunji. Kuchuluka kwake kumatheka pafupifupi maola atatu jakisoni. Kutalika kwa mphamvu kumachokera pa maola 17 mpaka 19.

Chofunikira chachikulu cha mankhwalawa Humulin NPH ndi isophan protamininsulin, yomwe imafanana kwathunthu ndi munthu. Ili ndi nthawi yayitali yochitapo kanthu. Amasankhidwa kuti.

Pankhani ya mankhwalawa, mankhwalawa amasankhidwa ndi adokotala. Komanso, monga lamulo, kuchuluka kwa Humulin NPH kumadalira thanzi la wodwala.

Imafunikanso kuperekedwa mokwanira mukamagwiritsa ntchito njira zakulera zamkamwa, komanso mahomoni a chithokomiro.

Koma ponena za kuchepetsa Mlingo wa insulin iyi, izi ziyenera kuchitidwa ngati wodwala ali ndi impso kapena.

Komanso kufunika kwa mahomoni opanga ma pancreatic amatsika ndikumawatenga ndi ma MA inhibitors, komanso beta-blockers.

Mwa zina zoyipa, kutchulidwa kwambiri ndi kuchepa kwakukulu kwa kuchuluka kwamafuta m'thupi lathu. Vutoli limatchedwa lipodystrophy. Komanso, nthawi zambiri, odwala amazindikira kukana insulini (kusakhalapo kwathunthu kwa vuto la insulin)

Koma Hypersensitivity zimachitika yogwira pophika mankhwala sizomwe zimachitika. Nthawi zina odwala amafotokoza kuswala kwambiri komwe kumadziwika ndi khungu loyipa.

Humulin Regular amakhala ndi tanthauzo la hypoglycemic. Chothandizira chophatikizika ndi insulin. Iyenera kulowetsedwa mapewa, ntchafu, matako kapena pamimba. Onse makonzedwe a intramuscular and intravenous amatha.

Momwe mulingo woyenera wa mankhwalawa, amadziwikiridwa payekhapayekha ndi dokotala wodziwa yekha. Kuchuluka kwa Humulin kumasankhidwa molingana ndi zomwe zili m'magazi.

Ndikofunika kudziwa kuti kutentha kwa zinthu zomwe zaperekedwa kuyenera kukhala koyenera. Masamba obayira ayenera kusinthidwa kuti malo omwewo asagwiritsidwe ntchito mopitilira kamodzi masiku 30.

Monga mukudziwa, mankhwalawa amaloledwa kuperekedwa limodzi ndi Humulin NPH. Koma zisanachitike, muyenera kuphunzira mwatsatanetsatane malangizo ophatikizira ma insulini awiriwa.
Mankhwalawa akuwonetsedwa kuti agwiritsidwe ntchito ndi insulin-amadalira, (kutaya chikumbumtima, chomwe chimadziwika ndi kusakhalapo kwathunthu kwa zochitika za thupi pazomwe zimachitika, komanso zomwe zimawoneka kuti ndizokwanira), komanso pokonzekera wodwala yemwe ali ndi vuto la endocrine, kuchitira opareshoni.

Amalemberanso kuvulala komanso matenda opatsirana pachakudwala matenda ashuga.

Pankhani ya pharmacological kanthu, mankhwalawa ndi insulin, yomwe imafanana kwathunthu ndi munthu. Amapangidwa motengera DNA yomwe imapangidwanso.

Ili ndi mndandanda wa ndendende wa amino acid womwe umakhala mu timadzi ta pancreatic ya anthu. Monga lamulo, mankhwalawa amadziwika ndi zochitika zazifupi. Chiyambitsi chake chabwino chimawonedwa pafupifupi theka la ola pambuyo poyendetsa mwachindunji.

Humulin M3 ndi othandizira amphamvu komanso othandizira a hypoglycemic, omwe amaphatikiza ma insulin aafupi komanso apakati.

Gawo lalikulu la mankhwalawa ndi chisakanizo cha insulin ya anthu osungunuka komanso kuyimitsidwa kwa isofan insulin. Humulin M3 ndi mtundu wina wa insulin wa anthu omwe amakhala ndi DNA. Ndi kuyimitsidwa kopanda phokoso.

Chikoka chachikulu cha mankhwalawa chimawonedwa ngati malamulo a kagayidwe kazachilengedwe. Kuphatikiza apo, mankhwalawa ali ndi mphamvu ya anabolic. M'misempha ndi minyewa ina (kupatula ubongo), insulin imakwiyitsa mayendedwe achilengedwe a glucose ndi amino acid, ikufulumizitsa mapuloteni anabolism.

Homoni ya pancreatic imathandizira kusintha glucose kukhala chiwindi glycogen, amalepheretsa gluconeogeneis, komanso amathandizira kusintha kwa glucose ochulukirapo kukhala lipids.

Humulin M3 akuwonetsedwa kuti agwiritse ntchito matenda ndi mthupi, monga:

shuga mellitus pamaso pazowonetsa zina posachedwa,
adapezeka koyamba matenda a shuga,
ndi matenda amtundu wa endocrine amtundu wachiwiri (osadalira insulini).

Zosiyanitsa

Zowoneka mosiyanasiyana zamitundu mitundu:

Humulin NPH . Ili m'gulu laopanga insulini zapakatikati.Mwa mankhwala omwe amapezeka nthawi yayitali monga othandizira odwala matenda a pancreatic hormone, mankhwalawa amaperekedwa kwa anthu odwala matenda ashuga. Monga lamulo, zochita zake zimayamba mphindi 60 pambuyo pa kutsata mwachindunji. Ndipo kuchuluka kwake kwakukulu kumawonedwa pambuyo pafupifupi maola 6. Kuphatikiza apo, zimatha pafupifupi maola 20 motsatana. Nthawi zambiri, odwala amagwiritsa ntchito jakisoni zingapo nthawi imodzi chifukwa chachedwa chifukwa cha mankhwala.
Humulin M3 . Ndiwosakanikirana kwapadera ndi ma insulin osakhalitsa. Ndalama zotere zimakhala ndi kuchuluka kwa NPH-insulin yayitali komanso pancreatic timadzi ta ultrashort komanso zochitika zazifupi,
Humulin Wokhazikika . Amagwiritsidwa ntchito poyambira kudziwa matenda. Monga mukudziwa, ikhoza kugwiritsidwa ntchito ndi azimayi oyembekezera. Mankhwalawa ndi m'gulu la mahomoni a ultrashort. Ndi gululi lomwe limatulutsa mwachangu kwambiri komanso nthawi yomweyo limachepetsa shuga la magazi. Gwiritsani ntchito mankhwala musanadye. Izi zimachitika kuti njira yogaya mafuta imathandizira kufulumiza kuyamwa kwa mankhwalawa munthawi yochepa kwambiri. Mahomoni ofulumira kuchitapo kanthu amatengedwa pakamwa. Zachidziwikire, ayenera kubweretsedwa kumalo amadzimadzi.

Ndikofunika kudziwa kuti insulini yokhala ndi nthawi yochepa ili ndi zotsatirazi:

ayenera kumwedwa pafupifupi mphindi 35 asanadye,
kuti musanayambike, muyenera kulowa ndi jakisoni,
Nthawi zambiri imayendetsedwa m'mimba m'mimba,
jakisoni wa mankhwala akuyenera kutsatiridwa ndi chakudya chotsatira kuti athetse zonse zomwe zingachitike.

Kodi pali kusiyana kotani pakati pa Humulin NPH insulin ndi Rinsulin NPH?

Humulin NPH ndi chithunzi cha insulin ya anthu. Rinsulin NPH imafanananso ndi mahomoni a pancreatic a anthu. Ndiye pali kusiyana kotani pakati pa awiriwa?

Ndikofunika kudziwa kuti onsewa ali m'gulu la mankhwala omwe amakhala ali nthawi yayitali kuchitidwe. Kusiyana kokhako pakati pa mankhwalawa ndikuti Humulin NPH ndi mankhwala achilendo, ndipo Rinsulin NPH amapangidwa ku Russia, motero mtengo wake umakhala wotsika kwambiri.

Wopanga

Humulin NPH imapangidwa ku Czech Republic, France, ndi UK. Humulin Wokhazikika wopangidwa ku USA. Humulin M3 amapangidwa ku France.

Monga tanena kale, Humulin NPH amatanthauza mankhwala omwe amakhala ali pakatikati pa zochita. Humulin Nthawi zonse amadziwika kuti ndi wowerengeka mwachidule. Koma Humulin M3 amadziwika kuti ndi insulin yokhala ndi yochepa.

Kuti musankhe ma analogue ofunikira a mahomoni a pancreatic ayenera kungokhala akatswiri a endocrinologist. Osadzisilira.

Makanema okhudzana nawo

Zokhudza mitundu ya insulini yomwe imagwiritsidwa ntchito pochiza matenda a shuga mu kanema:

Kuchokera pazidziwitso zonse zomwe zawonetsedwa m'nkhaniyi, titha kunena kuti kusankha koyenera kwambiri kwa insulin, kuchuluka kwake ndi njira yodulira zimatengera zinthu zingapo. Kuti mudziwe njira yoyenera komanso yotetezeka, muyenera kufunsa katswiri wodziwa za matenda a endocrinologist.

Insulin Humulin NPH: malangizo, analogues, ndemanga

1 ml muli:

ntchito: insulin yamunthu 100 ME,

Kuyimitsidwa ndi koyera, komwe kumachoka, ndikupanga koyera komanso kowoneka bwino - kopanda mawonekedwe kapena kopanda mtundu. Mtengo umasinthidwa mosavuta ndikugwedezeka modekha.

Gulu la Pharmacotherapeutic: wothandizila wa hypoglycemic - insulin ya nthawi yayitali yogwira ntchito ATX: & nbsp

A.10.A.C Kutalika kwapakatikati kosungira ndi mawonekedwe awo

Humulin® NPH ndi insulin yowerengeka ya anthu.

Chochita chachikulu cha insulin ndi kuphatikiza shuga kagayidwe. Kuphatikiza apo, imakhala ndi anabolic komanso anti-catabolic zotsatira zosiyanasiyana zamthupi. Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa ma amino acid, koma nthawi yomweyo kumachepa mu glycogenolysis, gluconeogeneis, ketogenesis, lipolysis, proteinabolism ndi kutulutsidwa kwa ma amino acid.

Kusiyana kwamwini pantchito ya insulin kumadalira zinthu monga mlingo, kusankha jakisoni, malo olimbitsa thupi, ndi zina zambiri.

- Matenda a shuga odwala matenda a insulin,

- matenda ashuga panthawi yoyembekezera.

Hypersensitivity kupita ku insulin kapena chimodzi mwazinthu za mankhwala,

Mimba ndi kuyamwa:

Odwala omwe ali ndi matenda a shuga mellitus nthawi yoyamwitsa angafunikire kusintha mlingo wa insulin, zakudya, kapena zonse ziwiri.

Mlingo ndi makonzedwe:

Mlingo wa Humulin® NPH umatsimikiziridwa ndi dokotala aliyense payekha malinga ndi kuchuluka kwa shuga m'magazi. Mankhwalawa amayenera kuperekedwa mwachangu.

Kutentha kwa mankhwala omwe amaperekedwa kuyenera kukhala kutentha kwambiri.

Ndondomeko ya insulin makonzedwe ali payekha.

Kukonzekera kwa Humulin® NPH mu mbale

Musagwiritse ntchito insulini ngati ili ndi mapokoso mukasakaniza. Osagwiritsa ntchito insulin ngati tinthu tating'ono tomwe timamatira pansi kapena makoma a vial, ndikupanga mawonekedwe a frosty.

Gwiritsani ntchito syringe ya insulin yomwe ikufanana ndi kuchuluka kwa insulin.

Ya Humulin® NPH m'makalata

Musanagwiritse ntchito, makatiriji a Humulin® NPH ayenera kugulitsidwa pakati pa manja khumi ndikugwedezeka, kutembenuka kwa 180 ° komanso khumi mpaka insulini itatsitsimuka kwathunthu mpaka itasandulika madzi osungunuka kapena mkaka. Osagwedezeka mwamphamvu, chifukwa izi zingapangitse mawonekedwe a chithovu, omwe amatha kusokoneza mlingo woyenera. Mkati kalikonse kalikonse ndi kakang'ono. mpira wamagalasi omwe amathandizira kusakanikirana kwa insulin. Musagwiritse ntchito insulini ngati ili ndi mapokoso mukasakaniza.

Chida cha cartridge sichimalola kuphatikiza zomwe zili ndi insulin zina mwachindunji mu katiriji palokha: makatiriji sanapangidwire kuti mudzazidwe.

Pamaso pa jekeseni, ndikofunikira kuti mudziwe bwino malangizo a wopanga kuti mugwiritse ntchito cholembera kuti mupeze insulin.

Mankhwala Humulin ®NPH mu syringe yothamanga

Pamaso jakisoni, muyenera kuwerenga Malangizo a QuickPen ™ Syringe pen Instruction.

Hypoglycemia ndizotsatira zoyipa zomwe zimachitika pokhazikitsa kukonzekera kwa insulin, kuphatikiza Humulin ® NPH. Hypoglycemia yamphamvu imatha kutha kwa chikumbumtima ndipo, mwapadera, amafa.

Ndi kugwiritsa ntchito nthawi yayitali - chitukuko ndichotheka lipodystrophy pamalo opangira jekeseni.

Wofatsa hypoglycemia mutha kuyimitsa pakumeza shuga kapena shuga. Kusintha kwa mlingo wa insulin, zakudya, kapena zolimbitsa thupi kungafunike.

Kuwongolera Hypoglycemia wabwino angathe kuchitidwa ntchito mu mnofu kapena subcutaneous makonzedwe a glucagon, kenako ingestion wa chakudya.

Ngati mukufunika kugwiritsa ntchito mankhwala ena, kuphatikiza insulin, muyenera kufunsa dokotala (onani gawo "Malangizo apadera").

Zotsatira zakusakanikirana kwa insulin yaumunthu ndi insulin yakuchokera kwa nyama kapena insulin ya anthu yopangidwa ndi ena omwe sanaphunzire.

QUICKPEN ™ SYRINGE HANDLES

Humulin® Regular QuickPen ™,Humulin® NPH QuickPen ™,Humulin® M3 QuickPen ™

MALANGIZO OTHANDIZA MALO OTSATIRA

CESANI LERANI ZINSINSI izi ASANAYITSE

Musanagwiritse ntchito syPinge ya QuickPen, werengani bukuli ndikutsatira malangizo ake ndendende. Ngati simutsatira malangizowa, mutha kulandira inshuwaransi yotsika kwambiri kapena kwambiri.

Musagwiritse ntchito cholembera ngati gawo lake lina lowonongeka kapena laphwanyika. Nthawi zonse tengani cholembera chopanda kanthu ngati mungataye cholembera kapena chikaonongeka.

Kukonzekera Kwachangu kwa Syninge

Werengani ndikutsatira malangizo ogwiritsira ntchito mankhwalawa.

Onani cholembera pa cholembera asanalowe jakisoni iliyonse kuti muwonetsetse kuti tsiku lakelo linatha ndipo mukugwiritsa ntchito mtundu woyenera wa insulini, musachotse chizindikiro pa cholembera.

Dokotala wanu wakupangira mtundu wa insulin wabwino kwambiri. Kusintha kulikonse kwa mankhwala a insulin kuyenera kuchitidwa kokha moyang'aniridwa ndi dokotala.

Musanagwiritse ntchito cholembera, onetsetsani kuti singanoyo imalumikizidwa kwathunthu ndi cholembera.

Tsatirani malangizo omwe aperekedwa apa.

Mafunso omwe amafunsidwa pafupipafupi okonzekera kukonzekera Penti ya QuickPen Syringe kuti mugwiritse ntchito

- Ndichite chiyani ngati mlingo wanga waposa 60? Ngati mlingo womwe wakupatsani uli pamwamba pa mayunitsi 60, mufunika jekeseni wachiwiri, kapena mutha kulankhulana ndi dokotala za nkhaniyi.

Kuyang'ana cholembera cha SyPinge cha QuickPen cha Insulin

Ngati simukuyang'ana insulin yanu musanayambe kudwala, mutha kulandira insulin yochepa kwambiri kapena yambiri.

Mafunso Omwe Amakonda Kufunsa za Kuchita Macheke a Insulin

- Chifukwa chiyani ndiyenera kuwerengera insulin yanga isanadye jakisoni iliyonse?

1. Izi zikuwonetsetsa kuti cholembera chakonzekera kumwa.

2. Izi zikutsimikizira kuti chinyengo cha insulin chimatuluka mu singano mukakanikiza batani la mlingo.

3.Izi zimachotsa mpweya womwe umatha kutola mu singano kapena katemera wa insulin panthawi yovomerezeka.