Amoxicillin kapena Azithromycin: ndibwino bwanji?
Azithromycin ndi Amoxicillin chifukwa chogwiritsidwa ntchito mosalekeza m'matenda ofananawo m'maganizo a anthu ambiri akhazikika ngati mankhwala amodzi. Komabe, zimasiyana kwambiri ndipo zimakhala ndi malo ake ogwiritsira ntchito.
Zomwe zili mu Azithromycin ndi Amoxicillin zimaphatikizanso zinthu zomwezo. Pazina ili, makampani ambiri azamankhwala amapanga zinthu zawo.
Njira yamachitidwe
- Azithromycin imagwira popanga mapuloteni mu cell ya bakiteriya, ndikusokoneza. Zotsatira zake, ma microorganism amataya kuthekera kwakukula ndi kuchuluka chifukwa cha kuchepa kwa zida zomanga.
- Amoxicillin amasokoneza mapangidwe a peptidoglycan, gawo lofunikira kwambiri la membrane wa bakiteriya, zomwe zimapangitsa kufa kwa tizilombo.
Kukaniza azithromycin m'mabakiteriya mitundu kumakhala kochepa kwambiri ndipo sikocheperako poyerekeza ndi amoxicillin. Ndi chiwopsezo cha tizilombo tating'onoting'ono tomwe timayambitsa matenda a Azithromycin ndi Amoxicillin omwe ndi momwe machitidwewa amathandizira.
Azithromycin adalandira:
- Matenda opatsirana a pharynx ndi ma toni,
- Kutupa kwa bronchi,
- Chibayo
- TV ya Otitis (kutupa kwa tympanic patsekeke),
- Sinusitis (chikondi cha amchimowo)
- Kutupa kwa urethral
- Cervicitis (kuwonongeka kwa ngalande yachiberekero)
- Matenda a pakhungu
- Zilonda zam'mimba, zilonda zam'mimba zophatikizana ndi matenda a Helicobacter pylori - kuphatikizapo mankhwala ena.
Zowonetsa kugwiritsa ntchito Amoxicillin:
- Kuwonongeka kwa kupumira thirakiti (m'mphuno wamkamwa, pharynx, larynx, trachea, bronchi, mapapu),
- Mbiri ya Otitis,
- Matenda opatsirana a genitourinary sphere,
- Matenda a pakhungu
- Zilonda zam'mimba, zilonda zam'mimba zophatikizana ndi matenda a Helicobacter pylori - kuphatikizapo mankhwala ena.
Contraindication
Azithromycin ndi yoletsedwa kugwiritsidwa ntchito ndi:
- Kusalolera kwa mankhwala osokoneza bongo kapena macrolide (erythromycin ,cacithromycin, etc.),
- Matenda a impso,
- Kuchepa kwa chiwindi,
- Nthawi ya mkaka wa m'mawere - imayima pakumwa mankhwala,
- Zaka mpaka zaka 12 - zamapiritsi ndi mapiritsi,
- Zaka mpaka zaka 6 - pakuyimitsidwa.
Zotsatira za kugwiritsa ntchito Amoxicillin:
- Hypersensitivity to penicillins (ampicillin, benzylpenicillin, etc.), cephalosporins (cevtriaxone, cefepime, cefuroxime, etc.),
- Matenda mononucleosis.
Zotsatira zoyipa
Azithromycin angayambitse:
- Kumva chizungulire, kutopa
- Kupweteka pachifuwa
- Chimbudzi
- Kutumiza
- Ziwengo kwa dzuwa.
Zotsatira zoyipa za Amoxicillin:
- Matenda am'mimba
- Tachycardia (palpitations)
- Kuchepa kwa chiwindi,
- Kuwonongeka kwa impso.
Tulutsani mafomu ndi mtengo
Mtengo wa azithromycin umasiyana malinga ndi wopanga:
- Mapiritsi
- 125 mg, 6 ma PC. - 195 p,
- 250 mg, 6 ma PC. - 280 r
- 500 mg, 3 ma PC. - 80 - 300 r,
- Makapisozi 250 mg, 6 ma PC. - 40 - 180 r,
- Ufa pakukonzekera kuyimitsidwa kwa 100 mg / 5 ml, 16,5 g, botolo 1 - 200 r.
Mankhwala otchedwa "Amoxicillin" amapangidwanso ndi makampani osiyanasiyana (kuti zitheke, mitengo ya mapiritsi ndi makapisozi amaperekedwa molingana ndi ma pc a 20.):
- Kuyimitsidwa pakamwa makonzedwe a 250 mg / 5 ml, botolo la 100 ml - 90 r,
- Kuyimitsidwa kwa jakisoni 15%, 100 ml, 1 pc. - 420 r
- Makapiritsi / mapiritsi (apezekanso ma PC 20.):
- 250 mg - 75 r,
- 500 mg - 65 - 200 r,
- 1000 mg - 275 p.
Azithromycin kapena amoxicillin - ndibwino?
Njira ya mankhwala a Azithromycin pafupifupi masiku atatu mpaka 6, Amoxicillin - mpaka masiku 10 - 14. Komabe, potengera izi zokha, sizingatheke kunena motsimikiza kuti ndi mankhwala ati omwe ali ndi mphamvu. Kwa bronchitis, tracheitis ndi matenda ena a kupuma, mankhwalawa akuyenera kuyamba ndi Amoxicillin. Komabe, kutali ndi odwala onse, mankhwalawa amakhala ndi chidwi. Chifukwa chake, ngati Amoxicillin adatengedwa chaka chatha, ndiye kuti Azithromycin ayenera kusankhidwa - mwanjira imeneyi, kupangidwa kwa antibayotiki odana ndi mabakiteriya kungathe kupewedwa.
Azithromycin ndi Amoxicillin - Kugwirizana
Nthawi zambiri ndikofunikira kugwiritsa ntchito mankhwala awiri nthawi imodzi chifukwa cha otitis media, sinusitis, ndi matenda ena omwe amakonda kukhala chibayo. Kutenga Azithromycin ndi Amoxicillin kumakuthandizani kuti mukwaniritse chiwonongeko chofulumira komanso chokwanira kwambiri cha woyambitsa matenda. Ndizoyenera kuganizira kuti kuphatikiza kwa maantibayotiki kumawonjezera kuyipa kwa thupi ndi chiwopsezo cha mavuto.
Amoxicillin amatani
Malangizowo akuwonetsa kugwiritsa ntchito amoxicillin mu bakiteriya matenda. Gawo lachitidwe ndilochulukirapo: kuchokera ku matenda amkati mwa kupuma kwamtunda kupita ku gawo la genitourinary. Koma mankhwalawa amagwiritsidwa ntchito nthawi zambiri matenda a ziwalo za ENT. Amoxicillin ndi mankhwala osokoneza bongo opangidwa ndi penicillin. Yopangidwa koyamba zaka 47 zapitazo ndi kampani yopanga mankhwala ku Britain Beecham.
Mfundo yofunika kuchitapo: kuwononga maselo mabakiteriya. Chifukwa chothamanga kwambiri cha mankhwalawa madzi amthupi. Yogwira ntchito motsutsana ndi ma virus omwe amachepetsa penicillin. Ichi ndichifukwa chake musanalandire, muyenera kudziwa bwino lomwe zovuta zomwe zimapangitsa kutupa. Kupanda kutero, chiopsezo chotenga chikhulupiriro champhamvu chimakulirakulira.
Katundu wa azithromycin
Mankhwalawa adawoneka mu 1980 mu kampani yaku Croatia PLIVA.
Njira yamachitidwe: Imachepetsa kukula kwa mabakiteriya ndi kufalikira kwawo.
Amawerengedwa kuti ndi amodzi mwa mankhwala othandizira kwambiri. Zimapirira bwino ma pathojeni osasokoneza gramu-gramu komanso gramu-zabwino za kupuma komanso matenda am'mimba. Amagwiritsidwa ntchito polimbana ndi mycoplasmas, chlamydia, streptococci.
Yogwirizana ndi vitamini C ndi mankhwala ena a bactericidal.
Kuyerekeza kwa Amoxicillin ndi Azithromycin: Zofanana ndi Kusiyana
Kuwona momwe mankhwalawa alili, zomwezi zimasonyezedwanso:
- onse ndi mibadwo yachitatu ya semisynthetics maantibayotiki
- kukwaniritsa bactericidal kwenikweni zimatengera kufunika ndende
- contraindicated: chiwindi kulephera, zomwe zimachepetsa kagayidwe
Kusiyana pakati pa mankhwalawa ndikofunikira.
- Malo a ndende: Azithromycin - m'magazi, Amoxicillin - mu plasma.
- Kuthamanga: Amoxicillin amapanga mofulumira
- Zotsatira zoyipa: Azithromycin ali ndi zochepa
- Mulingo wamagwiritsidwe: Amoxicillin limited
- Mtengo: Azithromycin ndiwokwera katatu
- Kutulutsa Fomu: Azithromycin imayikidwa m'matumba a mapiritsi atatu, makapisozi, ma ufa ndi kuyimitsidwa. Mlingo wothandiza: 500 mg, 250 mg, 125 mg. Amoxicillin amafalitsidwa m'mapiritsi kapena makapisozi a 250 ndi 500 mg. Ma grakeles okonzera kuyimitsidwa kwa ana amapangidwa.
T.O. Amoxicillin amagwiritsidwa ntchito mosiyanasiyana: amaloledwa kuthandizira ana aang'ono. Azithromycin - kwa gulu lochepa la odwala.
Amoxicillin ndi azithromycin - ndi mankhwala amodzi kapena osiyana?
Amoxicillin ndi azithromycin ndi mitundu yosiyana ya antibacterial. Komabe, nthawi zambiri amapatsidwa mankhwala omwewo omwe amatha kusokoneza odwala. Mankhwalawa amatenga gawo lalikulu pamsika wamankhwala othandizira antibacterial.
Amoxicillin ndi woimira ma penicillin opanga. Nawonso amakhala a beta-latcine antibiotics (pano akuphatikizanso cephalosporins, carbapenems ndi monobactams).
Muzochita zamankhwala, mankhwalawa agwiritsidwa ntchito kwambiri kuyambira 1970s. Ndizoyimira ma bactericidal othandizira, popeza momwe limagwirira ntchito ya antibayotiki limadalira kuthekera kwake kophatikizana ndi michere ya cytoplasmic yama cell ochepa ndikuwononga kukhulupirika kwawo. Chifukwa cha izi, pali kufa mwachangu kwamaluwa okhudzana ndi pathogenic.
Azithromycin ndiye woimira yemwe amaphunzira kwambiri azalides, omwe ndi amodzi mwa magulu am'magazi a antibacterial. Kuphatikiza pazapangidwe, imasiyananso m'njira ya bacteriostatic kanthu - tinthu tating'onoting'ono tomwe timalowa m'maselo tating'onoting'ono, komwe timatseka ntchito ya ribosomes.
Kuchita izi kumapangitsa kuti zikhale zosatheka kupitiliza kuchulukitsa ndipo zimapangitsa kuti Imfa yake iziteteza.
Sindikudziwa maantibayotiki omwe angasankhe bronchitis - Azithromycin kapena Amoxicillin. Mungalangize chiyani?
Onse azithromycin ndi amoxicillin ndi antibacterial othandizira omwe ali ndi zochitika zonse. Izi zikutanthauza kuti amalowa m'magazi a wodwalayo ndipo zimakhudza kugwira ntchito kwa ziwalo zosiyanasiyana. Nthawi yomweyo, kugwiritsidwa ntchito kwawo limodzi ndi mankhwala ena kumatha kukulitsa mphamvu ya antibacterial.
Chofunikira china chomwe chiyenera kukumbukiridwa ndikupezeka kwa zifukwa zokwanira zogwiritsira ntchito mankhwalawa. Masiku ano, nthawi zambiri, osati odwala okha, komanso madokotala amakupatsani mankhwala opatsirana ma virus omwe amapezeka m'matumbo amtundu wa kupuma komwe amathandiza.
Kugwiritsa ntchito mwa antibacterial wothandizila payokha kuyenera kupewedwa, chifukwa wodwalayo kapena abale ake nthawi zambiri sangathe kuwunika bwinobwino matendawa.
Chifukwa chake, kugwiritsa ntchito Azithromycin kapena Amoxicillin mwa iwo nthawi zambiri sikumapereka zotsatira zabwino, koma kumabweretsa zotsatira zoyipa.
Njira yothandiza kwambiri yodziwira kufunika kosankhidwa kwa maantibayotiki ndi kuchititsa kafukufuku wa bacteria, yemwe amathandizira kudziwa mtundu wa tizilomboti, komanso timazindikira kukhudzika kwake ndi ma antibacterial othandizira osiyanasiyana. Koma popeza njirayi imafunikira nthawi yochulukirapo, kuyambitsa chithandizo chamankhwala nthawi zambiri kumatsimikiziridwa ndi ziwerengero zamagazi a Laborator, zizindikiro zamankhwala komanso mkhalidwe wamba wodwala.
Chifukwa chake, kusankha maantibayotiki omwe amayenera kuperekedwa kwa bronchitis, ndibwino kufunsa dokotala woyenera.
Ndili ndi nkhawa kuti mwina ndikhale ndi mavuto ndikamamwa maantibayotiki. Kodi azithromycin ndi amoxicillin ndi otetezeka motani?
Wodwalayo ayenera kumvetsetsa kuti palibe mankhwalawa othandizira pakamwa kapena pakamwa popanda vuto lililonse. Ngati zotsatsa zilizonse zikanenedwa kuti mankhwalawo N. ndi otetezeka mosiyana ndi mankhwala oyipa, ndiye kuti mukutsimikiza - izi ndizosatheka.
Mankhwala akamagwiritsa ntchito, amatha kudziwa momwe amagwiritsidwira ntchito mankhwalawa, zambiri zimasonkhanitsidwa pazinthu zosayenera. Ndipo onsewa ayenera kuwonetsedwa mogwirizana ndi malangizo a mankhwalawo.
Azithromycin ndi Amoxicillin onse ndi mankhwala oteteza kumatenda, mukamamwa, mavuto osowa. Komanso, alibe poizoni m'thupi lathu. Komabe, ma frequency ndi mitundu ya zoyipa zomwe zimachitika mwa iwo ndizosiyana.
Mukamamwa Azithromycin, zizindikiro zosafunikira izi zimawonedwa nthawi zambiri:
- kukula kwa matenda opatsirana opatsirana a bakiteriya, ma virus kapena fungal etiology,
- Zizindikiro zakusokoneza mayendedwe am'mimba, (kutuluka kwa thukuta, kuwonda, kupweteka, kutaya chidwi, nseru, kutsekula m'mimba),
- kuwonjezeka kwakanthawi kwa kuchuluka kwa ma enzymes a chiwindi m'magazi,
- hyperbilirubinemia,
- kuwopsa kwa chapakati mantha dongosolo (Zizindikiro za chizungulire, kupweteka kwa mutu, kumva parasthesia, tinnitus, kuchuluka irritability, kugona tulo).
Ngati tizingolankhula za Amoxicillin, ndiye kuti vuto lalikulu ndi kugwiritsidwa ntchito kwake ndikosiyanasiyana. Nthawi zambiri, ndi omwe amakhala chifukwa chakulephera kwa mankhwalawa.
Mwachizolowezi, izi zimadziwika ndi zotupa pakhungu (kufiyira ndi kuyabwa kwambiri), kuwopsa kwa anaphylactic, matenda am'mimba. Milandu ya kuchepa kwa kuchuluka kwamaselo am'magazi, kuwonjezeranso matenda opatsirana am'mbuyo komanso chitukuko cha interstitial nephritis amafotokozedwanso.
Kodi azithromycin ndi amoxicillin angagwiritsidwe ntchito matenda omwewo?
Mwa zina. Azithromycin ndi mankhwala ena ake. Ikafika mu kayendedwe ka systemic, imadziunjikira mwachangu muzochitika zamankhwala othandizira kupuma. Komanso tinthu tating'onoting'ono timalowa m'maselo a chitetezo cha mthupi. Amakhala komwe amakhala kwa nthawi yayitali. Gawo limodzi la mankhwalawa limadziunjikiranso m'thupi lathu.
Kwa Amoxicillin, zinthu sizili bwino. Mankhwala amapezeka bwino ndikugawana mthupi la munthu. Komanso, simalowerera mu chiwindi ndipo imapukusidwa mu mawonekedwe osasinthika kudzera mu genitourinary thirakiti. Imalowanso bwino kudzera pazolepheretsa zina ndi zina. Chifukwa chake, mankhwalawa ali ndi mitundu yambiri yogwiritsidwa ntchito pochita dokotala.
Pali ma pathologies angapo omwe mungathe kufotokozera Azithromycin kapena Amoxicillin:
- chibayo chomwe chimapezeka m'magulu odwala osakhudzidwa ndi comorbidity,
- Bakiteriya,
- tracheitis
- pharyngitis
- laryngitis
- pachimake kapena matenda oopsa a tenillitis,
- otitis media.
Kuphatikiza apo, Amoxicillin amagwiritsidwa ntchito pochiza matenda a genitourinary system (cystitis, prostatitis, urethritis, pyelonephritis), musculoskeletal system (osteomyelitis), gawo loyamba la matenda a Lyme, matenda a Helicobacter pylori (monga gawo la mankhwala osakanikirana). Amadziwikanso kuti apewe zovuta, pakukonzekera ndi kuchititsa kusintha kwa maumwini ndi kuchitapo kanthu pochita opaleshoni.
Kodi mankhwalawa angalembedwe mu nthawi yachitatu ya mimba?
Mukamasankha mankhwala a antibacterial, chinthu chofunikira kwambiri ndi kusapezeka kwa poizoni kuubongo kuti muchepetse kusokonezeka.
Ngati tizingolankhula za Azithromycin ndi Amoxicillin, kudziwa kwa nthawi yayitali momwe amagwiritsidwira ntchito pachipatala kumawonetsa kuti palibe chidziwitso chakuwoneka kwa othandizira awa.
Pakati pamagulu ena a mankhwala, ma penicillin ndi macrolides amatengedwa kuti ndi ena otetezeka kugwiritsidwa ntchito m'gululi. Kuphatikiza kwawo ndi mkaka wa m`mawere kumatsimikiziranso.
Maphunziro angapo a nyama adachitidwapo pogwiritsa ntchito mankhwalawa, omwe sanasonyeze kupatuka panjira yeniyeni yomwe mayi amakhala nayo pakati.
Kutengera ndi izi, bungwe la ku America lotha kuwongolera zamankhwala FDA lipereka onse Amoxicillin ndi Azithromycin gulu B, zomwe zikuwonetsa chitetezo cha mankhwalawa kwa mwana wosabadwayo. Amaloledwa kusankha pamaso pa umboni wokwanira.
Kodi pali kusiyana kwamitengo pakati pa mankhwalawa?
Ngati mungayang'ane mankhwala, ndizosavuta kuwona kuti Amoxicillin, mosasamala kanthu za wopanga, ali mgulu la mitengo yotsika mtengo kuposa Azithromycin. Izi zimachitika makamaka chifukwa cha nthawi yayitali yopanga mankhwalawa komanso mtengo wake.
Amoxicillin amamasulidwa kwa zaka 10 padziko lapansi, ndipo munthawi imeneyi opanga ambiri anayamba kupanga mankhwala ochepetsa mphamvuyi m'mazina osiyanasiyana ogulitsa.
Mitengo yapamwamba ya azithromycin imalimbikitsidwanso ndi zochitika zaposachedwa, malingana ndi momwe ma macrolides amapitilira kukondedwa kuposa ma penicillin opangidwa.
Zizindikiro ndi contraindication kuti mugwiritse ntchito
Mankhwalawa amagwiritsidwa ntchito pakamwa pa matenda otsatirawa:
- matenda a ziwalo za ENT komanso kupuma (kutukusira kwa ma mucous membrane wa pharynx ndi / kapena palatine mamisempha oyambitsidwa ndi streptococci, kutupa kwa khutu lapakati, kutupa kwa bronchi ndi mapapu, kutupa kwa larynx ndi paranasal sinuses),
- matenda a pakhungu ndi minofu yofewa,
- matenda obwera chifukwa
- kuwonongeka kwa genitourinary system chifukwa cha chlamydia (kutupa kwa khomo pachibelekeropo ndi urethra),
- kuthetseratu kwa H. pylori (monga gawo la chithandizo chovuta).
Ma infusions amathandizira matenda oopsa omwe amayamba chifukwa cha zovuta zosagwirizana (kuwonongeka kwa maliseche, chikhodzodzo, rectum, chibayo cha anthu wamba).
Mankhwala ndi contraindicated vuto la hypersensitivity, vuto laimpso ndi / kapena chiwindi ntchito. Gwiritsani ntchito mosamala:
- pa mimba ndi yoyamwitsa,
- makanda
- ana ochepera zaka 16 ndi ana omwe ali ndi vuto la chiwindi kapena impso,
- ndi arrhythmia (pakhoza kukhala zosokoneza mu mtundu wamagetsi ndi kutalika kwa gawo la QT).
Mankhwalawa amalembedwa pakamwa kapena kudzera m'mitsempha. Mlingo umakhazikitsidwa pozindikira, kuopsa kwa matendawa, kuzindikira kwa mavuto a pathogen. Mkati tengani 1 r / tsiku 0,25-1 g (kwa achikulire) kapena ana 5-10 mg / kg (ana osaposa zaka 16) ola limodzi musanadye kapena maola awiri mutadya.
Mothandizidwa kugwirira ntchito kwakanthawi 1 ora limodzi. Inkjet kapena jakisoni wa intramus ndi oletsedwa.
Kuchita zinthu zina
Kudya chakudya, mowa kapena ma antacid amachepetsa ndikuchepetsa kuyamwa.
Tetracycline ndi chloramphenicol amalumikizana ndi azithromycin, kukulira kwake, ma lincomycins - amachepetsedwa, akutsutsana nawo.
Mukumwa mankhwalawa azithromycin, mankhwalawa a Midazolam, Carbamazepine, Sildenafil, Didanosine, Triazolam, Zidovudine, Efavirenza, Fluconazole ndi ena mwa mankhwalawa. Awiri omalizawa amakhalanso ndi chidwi ndi ma pharmacokinetics a antibayotiki pawokha.
Pogwiritsa ntchito ndi Nelfinavir, kuwunika kwa wodwalayo ndikofunikira kwa chiwindi ndi ziwalo zamkhutu, chifukwa C imachuluka kwambirimax ndi AUC antiotic, yomwe imabweretsa zotsatira zoyipa. Ndikofunikanso kuwunika thanzi la wodwalayo komanso thanzi lawo akamatengedwa ndi Digoxin, Cyclosporin ndi Phenytoin, chifukwa chakuti mwina akuwonjezera kuchuluka kwawo m'magazi.
Ndi munthawi yomweyo kugwiritsa ntchito maantibayotiki omwe ali ndi alkaloids p. Claviceps imatha kukhala ndi poizoni, monga vasospasm ndi dysesthesia. Ngati pakufunika kugwiritsa ntchito pamodzi ndi Warfarin, nthawi ya prothrombin iyenera kuyang'aniridwa mosamala chifukwa ndizotheka kuwonjezera prothrombin nthawi komanso pafupipafupi kukha magazi. Komanso, mankhwalawa sagwirizana ndi heparin.
Kufanizira kwa antibiotic
Zikuwonekeratu kuti maantibayotiki awiriwa ali ndi zofanana. Komabe, muyenera kudziwa kuti ndi iti yomwe ili yothandiza kwambiri. Kuti muyankhe funso, lomwe ndi labwino - Azithromycin kapena Amoxicillin, ndipo ngati pali kusiyana pakati pawo, muyenera kuwayerekeza ndi mfundo:
- Onsewa ndi mankhwala osokoneza bongo a antibacterial.
- Onse amawonetsera bacteriostatic muzinthu zazing'ono komanso zabwinobwino, komanso bactericidal zotsatira zazikulu.
- Ntchito ya Azithromycin ndi yotalikirapo kuposa Amoxicillin, yomwe imapereka mwayi pa mankhwalawa matenda opatsirana ndi tizilombo toyambitsa matenda osadziwika.
- Maantibayotiki onsewa amagwiritsidwa ntchito pa matenda ofanana, koma Amoxicillin ali ndi matenda ambiri chifukwa cha matenda am'mimba komanso m'mimba.
- Azithromycin ndiwotetezeka kuposa amoxicillin, popeza amaloledwa mosamala kuti azitha kugwiritsa ntchito amayi apakati ndi ana osakwana zaka 16.
- Mlingo wa azithromycin mwa ana umachepetsedwa pang'ono, zomwe zingasonyezenso kuti chitetezo chake ndichokwera kuposa cha Amoxicillin.
- Nthawi yomweyo, kuphatikiza kwa Azithromycin kumakhala kotsika: mukamamwa ndi mankhwala ena (ma antacid, fluanoazole, ndi zina) ndikamamwa ndi chakudya, amatha kusintha mayamwidwe a antibayotiki, omwe angakhudze mlingo woyamwa ndi zotsatira zake, pomwe Amoxicillin ali wodziyimira yekha wogwiritsa ntchito mankhwala ena.
- Azithromycin amalowetsedwa pang'onopang'ono (maola 2-3) kuposa Amoxicillin (maola 1-2).
- Amoxicillin ndiwopanda ntchito polimbana ndi mabakiteriya okhala ndi penicillinase.
- Mankhwala onse omwe amayerekezedwa ndi ma virus amapatsira zotchinga za histoeticological popanda zovuta, zimakhala zokhazikika pamalo achilengedwe am'mimba ndipo zimagawidwa mwachangu kuzinthu zonse.
- Azithromycin, mosiyana ndi Amoxicillin, ali ndi chidwi, akumasulidwa kuchokera kwaonyamula kokha pamaso pa mabakiteriya, ndiko kuti, ziwalo zokhazokha.
Kugwirizana kwa Amoxicillin ndi Azithromycin ndi chilengedwe mwachilengedwe, kuchepetsa kugwiritsa ntchito kwa mankhwala onse awiri, chifukwa chake simuyenera kuwatenga pamodzi. Ngakhale kufanana kwa mitundu iwiriyi kuyerekeza, wina akhoza kunena kuti Azithromycin ndiyabwino kuposa Amoxicillin popeza ndiwotetezeka, ali ndi zochita komanso kusankha kwakukulu.
Komabe, siziyenera kuganiziridwa kuti Amoxicillin ndioyipa - zabwino zake zimaphatikizapo kuyamwa kwakukulu ndikugwirizana ndi mankhwala ena.
Chifukwa chake, funso loti "Ndi maantibiotic ali bwino?" Titha kuyankhidwa kuti Azithromycin ndiwabwino kuposa Amoxicillin, zomwe sizitanthauza kuti yotsirizirayi siyoyenera kuyang'aniridwa - nthawi zina (mwachitsanzo, ndi matenda am'mimba) imawoneka bwino ndipo ikulimbikitsidwa ntchito.
Zomwe zimakhala zamphamvu
Musanasankhe mmodzi wa iwo, lingalirani za malingaliro a dokotala. Kuchita bwino kwa mankhwalawa kumatengera izi. Pamatenda achilengedwe omwe sakudziwika, Azithromycin azigwira ntchito. Idzakhala chisankho chabwino kwambiri cha ziwopsezo za penicillin. Kapenanso kumwa mankhwala ogwiritsira ntchito mankhwala osokoneza bongo sikuyenda bwino. Amoxicillin nthawi zambiri amapatsidwa matenda a ziwalo za ENT: sinusitis, tonsillitis, bronchitis, chibayo, atitis media. Adadzitsimikizira mwachipambano muutoto wa ana. Azithromycin ndi ana opitirira zaka 12.
Zomwe zimakhala zotsika mtengo
Kusiyanitsa kwamtengo kumasiyana katatu: Azithromycin - ma ruble 120. kwa makapisozi 6 250 mg., Amoxicillin 20 mapiritsi a 0,5 adzagula ma ruble 45.
Mankhwala, gulu la mankhwala limaperekedwa. Zonse zakunja ndi zopangidwa ku Russia.
Magawo a Amoxicillin: Abiklav, Amoksikar, V-Moks, Upsamoks.
Zolemba zogwiritsira ntchito
Kugwiritsa ntchito azithromycin ndizovomerezeka panthawi yoyembekezera, mosiyana ndi Amoxicillin. Onsewa sakuvomerezeka.
Tetracyclines ndi chloramphenicol, akagwiritsidwa ntchito limodzi ndi mankhwala, amalimbikitsa.
Kuphatikiza mankhwala a matenda a Heliobacter, Azithromycin amapatsidwa nthawi yomweyo ndi metronidazole.
Ndemanga za madotolo ndi odwala
Julia, wothandizira wakuchipatala, wazaka 39
Mankhwala ndi olimba, ngati agwiritsidwa ntchito molingana ndi malangizo! Osadzipereka.
Alexey, wazaka 43
Panali ziwopsezo ku Amoxcillin. Omwe amathandizira.
Masika aliwonse, ndimakhala ndimazizira, ndimazizira, m'chipatala amalemba kuti "azithromycin" - amapita mwachangu.
Chidziwitso choperekedwa sichingafanane ndi kupezeka kwa dokotala.
Mawonekedwe a Azithromycin
Azithromycin ndi macrolide opanga pang'ono a azalide subclass. Mphete ya lactone imapangitsa molekyu kuti ikhale asidi momwe ingathere. Kampani "Pliva" yokhala ndi dzina la azithromycin mu 1981. Chomwe chimagwiritsidwa ntchito ndi azithromycin (mwanjira ya dihydrate). Mankhwalawa ali ndi mitundu yotulutsira iyi:
- mapiritsi okutidwa: 250 ndi 500 mg,
- makapisozi: 250 ndi 500 mg,
- ufa woyimitsidwa pakamwa: 100, 200 ndi 500 mg / 20 mg.
Maanti-awonetsero ambiri. Imagwira ntchito motsutsana ndi mitundu yosiyanasiyana ya streptococci, Staphylococcus aureus, Neisseria, hemophilus bacillus, clostridia, mycoplasmas, chlamydia, paleponema, ndi ena. Yogwiritsa polimbana ndi mabakiteriya a gramu omwe amalimbana ndi erythromycin.
Zisonyezo zakukhazikitsidwa kwa azithromycin ndi:
- chapamwamba kupuma thirakiti matenda - pharyngitis, laryngitis, tracheitis,
- bronchitis ndi chibayo, kuphatikiza atypical,
- sinusitis, otitis media, sinusitis,
- malungo ofiira,
- matenda a pakhungu,
- matenda opatsirana pogonana
- zovuta mankhwala a chironda chachikulu cha m'mimba thirakiti.
Mankhwalawa sagwiritsidwa ntchito:
- ndi chidwi chamunthu payekha,
- ndi aimpso kapena chiwindi kulephera pa gawo la kubwezera,
- mwa ana ochepera zaka 12 kapena ochepera 45 makilogalamu,
- nthawi yomweyo ndi mankhwala a mtundu wa ergotamine.
Pazifukwa zaumoyo, amapatsidwa nthawi yoyembekezera komanso yoyamwitsa. Moyang'aniridwa ndi dokotala, kuwonongeka kwapakati pamatenda aimpso ndi kwa chiwindi kumayikidwa (ndi mtundu wa creatinine chilolezo cha 40 ml / min ndi kupitirira, mulingo wake siwokhala), chosinthika cha matenda amtima.
Kutengera zakumbuyo kwa kutenga Azithromycin, zotupa, kuyabwa pakhungu, kupweteka kwa mutu, chizungulire, nseru, m'mimba kumachitika.
Zotsatira zotsatirazi ndizotheka kumwa mankhwalawa:
- zotupa, kuyabwa,
- mutu, chizungulire,
- nseru, kutsegula m'mimba,
- zolimba, kugunda kwamtima,
- kuchuluka kwa michere ya creatinine ndi chiwindi mu madzi am'magazi,
Amoxicillin kanthu
Amoxicillin ndi penicillin wopanga yemwe amagwiritsa ntchito mphamvu za aerobes - staphylococci, streptococci, Escherichia coli, Helicobacter pylori, ndi zina. Linapangidwa mu 1972. Amoxicillin amalepheretsa kupanga ma protein a membrane a tizilombo tating'ono tomwe timagawikana komanso kukula, chifukwa cha zomwe tizilombo toyambitsa matenda timafa. The yogwira mankhwala ndi amoxicillin.
Mankhwalawa ali ndi mitundu ingapo yomasulidwa:
- mapiritsi: 250 ndi 500 ndi 1000 mg,
- ufa woyimitsidwa pakumwa pakamwa: 125, 250 ndi 500 mg (koyenera kuchitira ana),
- makapisozi: 250 mg.
Amoxicillin imaphatikizidwa pakuphatikizidwa kwa trihydrate. Muli zigawo zothandiza: magnesium, calcium, starch.
Amoxicillin amatanthauza semisynthetic penicillin. Amadziwika ndi kutchulidwa antibacterial. Imakhala ndi zokhumudwitsa za meningococci, Pseudomonas aeruginosa ndi Escherichia coli, Helicobacter pylori, staphylococcus, streptococcus, etc.
Mankhwalawa amalimbana ndi gastric acid HCl. The achire zotsatira zimatheka ndi kupondereza kapangidwe ka mapuloteni am'maselo a maselo mabakiteriya munthawi yamagawidwe ndi kukula, ndikupangitsa kufa kwa tizilombo.
Zisonyezero zogwiritsidwa ntchito:
- matenda am'mimba komanso m'munsi kupuma, nthawi zambiri chibayo, bronchitis,
- rhinitis, sinusitis, sinusitis, tonsillitis,
- matenda akumva - otitis media,
- matenda a impso, chikhodzodzo,
- kuwonongeka pakhungu ndi minofu yofewa ndi mabakiteriya,
- meningitis
- kupewa mabakiteriya pambuyo opaleshoni,
- matenda opatsirana pogonana,
- zilonda zam'mimba (monga gawo la zovuta mankhwala).
Amoxicillin sinafotokozedwe pa nthawi yoyembekezera komanso yoyamwitsa, kulephera kwa chiwindi mu gawo la kuwonongeka.
- pa mimba ndi yoyamwitsa,
- sayanjana ndi zigawo zake,
- chiwindi kulephera,
- leukemia ndi mononucleosis,
- mphumu ya bronchial ndi hay fever.
Amoxicillin amalekeredwa bwino, koma ngati mulibe kuunika, zotsatirapo zotsatirazi zimachitika:
- kupumirana mseru, kuphwanya kwamphamvu malingaliro,
- kuyabwa, urticaria,
- kuphwanya magazi oyera
- mutu, chizungulire.
Kodi pali kusiyana kotani ndi kufanana pakati pa Azithromycin ndi Amoxicillin?
Mankhwala ali ndi zinthu zofananira izi:
- Amakhala ndi zochita zingapo, zamagulu opanga antibacterial. Mu 80% ya milandu, amagwira ntchito molimbana ndi tizilombo toyambitsa matenda omwewo.
- Mitundu ya kumasulidwa - mapiritsi, ufa wa kuyimitsidwa, makapisozi.
- Kugwiritsidwa ntchito muzochita za ana.
- Lowani modutsa zotchinga zamagazi ndi ubongo. Ntchito mankhwalawa neuroinfections. Kuikidwa pa mimba pokhapokha pazifukwa zaumoyo.
- Wolekeredwa bwino, khalani ndi mtundu wosavuta wa mankhwala.
Azithromycin ndi Amoxicillin siofananira, ali ndi zosiyana zingapo zazikulu:
- Magulu osiyanasiyana a pharmacological: Azithromycin - ochokera ku macrolides, Amoxicillin - penicillin.
- Azithromycin ali ndi zochitika zambiri. Ndi mankhwala osankha matenda omwe ali ndi tizilombo toyambitsa matenda osadziwika.
- Amoxicillin imatha kutumizidwa kuphatikiza mankhwala ambiri, kudya kwake osadalira kudya. Azithromycin imagwirizana ndi mankhwala angapo, mwachitsanzo, ma antacid, ma antimycotic, etc. Sangatengedwe ndi chakudya, chifukwa kunyowa m'mimba ndi matumbo amachepetsa kwambiri.
- Azithromycin ndiotetezeka. Amawonetsedwa mosamala kwambiri kwa odwala omwe ali ndi impso ndi kwa chiwindi. Ganizirani momwe zimapangidwira pamtima dongosolo, lomwe ndilofunika kwambiri kwa odwala omwe ali ndi arrhasmia.
- Amoxicillin amaloledwa kuchita machitidwe a ana kuyambira masiku oyamba amoyo wamwana mu mawonekedwe a kuyimitsidwa kwa 0,125 g. Azithromycin akhoza kulembedwa kwa ana azaka 12 zokha.
- The causative othandizira a angina nthawi zambiri amapanga lactamase - michere yomwe inactivate Amoxicillin. Chifukwa chake, ndi tonsillitis, madokotala odziwa zambiri amapereka mankhwala a Azithromycin.
- Macrolide imagwira ntchito motsutsana ndi chlamydia, ureaplasmas ndi mycoplasmas. Kafupifupi masiku atatu a piritsi 1 patsiku amakayikira. Amamuwona ngati mankhwala osankha kuchiza matenda opatsirana pogonana.
Kodi ndi bwino kutenga - azithromycin kapena amoxicillin?
Ndi ati mwa mankhwalawa omwe ayenera kutumikiridwa - Azithromycin kapena Amoxicillin, ndiye adokotala amawaganizira kuti apeza matendawa, madandaulo a wodwalayo, kuopsa kwa matendawa.
Azithromycin imadziunjikira mwachangu mu minofu ya kupuma. Izi zimapangitsa kuti azikondedwa ndi chibayo, kuphatikiza mawonekedwe a atypical.
Amoxicillin amagawananso mokwanira m'thupi. Sichikhala mu chiwindi. Amathira mkodzo. Chifukwa chake, mankhwalawa amagwiritsidwa ntchito kwambiri pochotsa impso, cystitis, urethritis. Nthawi zambiri, mankhwalawa amatchulidwa kuti apewe mabakiteriya a postoperative.
Kodi Azithromycin ingalowe m'malo ndi Amoxicillin?
Muzochitika zamankhwala, kusintha kwa Amoxicillin ndi Azithromycin kumapezeka pochiza matenda am'mapazi am'munsi komanso ochepa kupuma, komanso machitidwe a otorhinolaryngologist. Nthawi zina, mankhwala a magulu ena amasankhidwa.
Nthawi yomweyo, Azithromycin ndi Amoxicillin sangathe kugwiritsidwa ntchito - mankhwalawa amapondana.
Malingaliro a madotolo
Nataliya, dokotala wa ana, St.
Ana nthawi zambiri amadwala matenda osiyanasiyana omwe amafuna maantibayotiki. Ndidasankha Amoxicillin ndi Azithromycin. Wotsirizira ndi omwe amapatsidwa bronchitis, chibayo. Nthawi zina zonse, ndimayamba kulandira chithandizo ndi Amoxicillin. Mankhwala onse awiriwa ali ndi mitundu yosavuta yotulutsira matendawa, amalekeredwa bwino, ndipo amaperekanso mphamvu. Zimapezeka pamtengo. Ndiosavuta kugula ku pharmacy iliyonse.
Sergey, Therapist, Khabarovsk
Pa zaka 5 zapitazi, vuto la chibayo layamba pafupipafupi. Onse okalamba ndi achinyamata odwala. Ndikuganiza kuti mankhwala abwino kwambiri pamenepa ndi Azithromycin. Ndondomeko yoyenera yogwiritsira, njira yachangu: masiku atatu okha. Imalekeredwa bwino, palibe zodandaula zilizonse zoyipa. Muzochitika zina zonse zofuna maantibayotiki, Amoxicillin ndi mankhwala. Kuphatikizika kambiri ndi kulolera bwino kunapangitsa kuti ikhale mankhwala omwe amadziwika kwambiri pakati pa odwala.
Ndemanga za Odwala
Irina, wazaka 32, Kazan
Adadwala kwambiri: zidali zowawa kumeza, kutentha kudakwera ndipo kuzizira kudawonekera. Dziwani ndi tonsillitis. Dokotala nthawi yomweyo adatumiza Azithromycin. Ndinayamba kutenga, koma panali mseru, chizungulire. Ndinafunika kusintha Amoxicillin. Pambuyo pake, kutentha kunachepera, kuzizira kumadutsa. Palibe mavuto omwe adachitika.Mankhwalawa adathandiza, ndipo zilonda zapakhosi zidapita popanda zovuta.
Elena, wazaka 34, Izhevsk
Mwana wanga wamkazi ali ndi zaka 12. Posachedwa ndidwala ndi bronchitis. Dokotala wa ana adapereka Azithromycin. Pa tsiku lachiwiri la chithandizo, adayamba kuyabwa kwambiri pakhungu ndi zotupa, ndipo m'mimba mudatuluka. Dokotalayo adalongosola izi ngati kusalolera payekha ndikusintha mankhwalawo ndi Amoxicillin. Mankhwala olimbana ndi mankhwalawa amalekeredwa bwino, palibe zoyipa zomwe zimachitika. Kuphatikiza apo, adatha kuthana ndi matendawa mwachangu.
Ivan, wazaka 57, Arkhangelsk
Amadwala matenda opatsirana pachimake. Ndimaganiza kuti zitha, koma sizinatheke. Mphuno imaletseka nthawi zonse, + 37.2 ... + 37.5 ° C madzulo, kuphulika kwa mutu, thukuta. Ndinapita kwa adotolo. Adatumiza ku x-ray, zomwe zidawonetsa kuti ndili ndi sinusitis yapakati. Amoxicillin adalembedwa. Ndinkamwa masiku 5, sizinandivute. Anasintha maantibayotiki kuti Azithromycin. Ndimamva kusintha ndikutha tsiku loyamba. Kutentha kunabwezeretsa, kupweteka kumutu kunachepa, ndipo ndinayamba kupumira mwa mphuno yanga. Anadutsa maphunziro athunthu, akumva bwino. Mankhwala abwino.
Dokotala adalemba Amoxicillin wa tonsillitis. Komabe, atatha masiku 5 oyang'anira, palibe kusintha. Kodi ndingasinthe ndikutenga azithromycin?
Zomwe zafotokozedwa mufunsoli ndizofala kwambiri pantchito ya dokotala. Chifukwa chakugwiritsidwa ntchito kwakanthawi, Amoxicillin yatha mphamvu kwambiri. Izi zidachitika chifukwa chakuti tizilombo tambiri tosiyanasiyana tomwe tidatha kusintha mankhwalawo, tidayamba kupanga puloteni yapadera, penicillinase, yomwe imangophwanya tinthu tomwe timagulu tokhala ndi antibayotiki.
Kafukufuku waposachedwa pamutuwu atsimikizira izi. Chifukwa chake, Amoxicillin osakanikirana ndi clavulanic acid tsopano adayikidwa.
Kodi Azithromycin ali othandiza kwambiri? Kukana kwa microflora kwa icho kumakhalabe kotsika. Chifukwa chake, pamene kutenga ma penicillin opanga sanapereke zotsatira, ndi mankhwala omwe mungasankhe.
Ndinkakhala ndi zovuta zomwe zimachitika ndikamamwa Amoxicillin ndi Ceftriaxone. Kodi ndizotetezeka bwanji kumwa mankhwala azithromycin?
Pakati pa mankhwala onse a gulu la beta-lactam antibacterial, pamakhala kukhudzika kwa mtanda. Izi ndichifukwa choti kapangidwe kake kamankhwala kamafanana, thupi silimawasiyanitsa ndi amodzi.
Komabe, azithromycin ndi wa gulu losiyana la mankhwala. Chifukwa chake, ndichisankho chachikulu pamaso pa zovuta za penicillin, cephalosporins, monobactam kapena carbapenem mwa odwala. Kugwiritsa ntchito kwake kwa odwalawa kwatsimikizira chitetezo chokwanira.
Ngati wodwalayo ali ndi nkhawa, ndiye kuti kuyesa kwa khungu mosavuta pakakhala kuperewera kwa mankhwalawo.
Kodi Amoxcillin kapena Azithromycin angalembedwe mwana wazaka chimodzi?
Chowoneka cha ma antibacterial othandizira awa ndikuti amatha kugwiritsidwa ntchito pazaka zilizonse za wodwala. Ndipo ngati kwa akuluakulu amapezeka mu mawonekedwe a piritsi, ndiye kuti njira yabwino ndi kugwiritsa ntchito kwa ana pali madzi. Zimakuthandizani kuwerengera kuchuluka kwa mankhwalawa kwa mwana winawake, kutengera kulemera kwake ndi msinkhu wake.
Pochita, mutha kugwiritsa ntchito mankhwalawa chaka choyamba cha moyo popanda kuwopa zovuta.
Ndani mwa awa omwe ali ndi antibacterial omwe ali bwino kwambiri - Azithromycin kapena Amoxicillin?
Ndikosavuta kuyankha mosabisa funso la zomwe zili bwino kuposa Amoxicillin kapena Azithromycin, popeza maantibayotiki ali ndi zisonyezo zingapo zogwiritsidwa ntchito komanso mndandanda wazomera zovuta.
Iliyonse ya mankhwalawa ili ndi zabwino komanso zovuta zake.
Ubwino wopambana wa Azithromycin ndi magwiridwe ake, chifukwa mabakiteriya amakana pang'ono kuposa Amoxicillin (makamaka popanda kuphatikiza ndi clavulanic acid, monga Amoxiclav). Kugwiritsa ntchito kosavuta kumayankhulanso ndi kumuyandikira, popeza mankhwalawa amatenga matendawa kamodzi pa tsiku kwa masiku atatu.
Ubwino waukulu wa Amoxicillin ndikupezeka kwake. Komabe, pakuchita kuchipatala chaka chilichonse amagwiritsidwa ntchito mopitilira apo.
Kanemayo amakamba za momwe mungachiritsire mwachangu chimfine, chimfine kapena SARS. Maganizo a dokotala wodziwa zambiri.
Katundu wa mankhwala Azithromycin
Mankhwalawa ndi a macrolide anti cell a azalide subgroup. Mlingo wambiri, umakhala ndi bacteriostatic, koma mu milingo yayikulu amawonetsa katundu wa bactericidal. Imatha kupititsa patsogolo ntchito za opha T, kupewetsa kuphatikizira kwa oyimira pakati otupa ndikuthandizira kupanga ma interleukins, ndikupanga zina zotsutsana ndi kutupa ndi immunomodulating.
Azithromycin amatha kukhala ndi bactericidal, makamaka pokhudzana ndi: pneumococcus, gonococcus.
Azithromycin imamangirira yaying'ono ya ribosomal m'maselo a bakiteriya, potero kutsekereza enzymatic ntchito ya peptide translocase ndikusokoneza mapuloteni a biosynthesis. Izi zimapangitsa kuti pang'onopang'ono kukula kwa mabakiteriya komanso kuthekera kwatsopano kwa kubereka. Chiwerengero cha tizilombo toyambitsa matenda chimakhala chochepa ndipo chitetezo cha wodwalayo chimatha kupirira nawo pawokha.
Mankhwala amadziwika ndi lipophilicity komanso asidi wambiri kukana. Tizilombo toyambitsa matenda tomwe timagwirizana ndi zochita za erythromycin zimateteza azithromycin (bacteroids, enterobacteria, salmonella, shigella, bacilli gramu-negative, etc.). Chifukwa cha pharmacodynamics ya mankhwalawa, kuchuluka kwazowonjezera zomwe zimapangidwa zimapangidwa mu minofu yomwe ili ndi kachilombo, motero imatha kupereka mphamvu ya bactericidal, makamaka pokhudzana ndi:
- pneumococcus
- gonococcus,
- pyogenic streptococcus,
- Helicobacter pylori,
- hemophilic bacillus,
- causative othandizira a pertussis ndi diphtheria.
Ili ndi imodzi mwamankhwala otetezeka kwambiri. Mwayi wopanga zovuta zoyipa umakhala pafupifupi 9%. Ngati ndi kotheka, chitha kugwiritsidwa ntchito pa nthawi yapakati. Amadziwika ndi zovuta zamtundu wamtundu wa anti-macrolide.
Kodi pali kusiyana kotani?
Kukonzekera kumasiyana mosiyanasiyana. Amoxicillin ndi chithunzi cha Penicillin, pomwe Azithromycin ndi mankhwala amakono kwambiri ochokera ku gulu la macrolide.
Zotsirizirazi zimakhala ndi zochita zowonjezereka. Imagwira ntchito yolimbana ndi mycoplasmas, zowonjezera- komanso ma patracellular tizilombo toyambitsa matenda, komanso anaerobes, monga bacteroids, clostridia, peptococci ndi peptostreptococci. Nthawi yomweyo, kukonzekera kwa amoxicillin kungachepetse zochitika za Escherichia coli, mitundu ina ya Salmonella, Klebsiella ndi Shigella, omwe mankhwalawa a macrolide sangathe kupirira.
Chifukwa cha kusefera koyambirira m'chiwindi, dongosolo la bioavailability la azithromycin limatsitsidwa mpaka 37%. Kudya kumapangitsa kuti zikhale zovuta kutulutsa kuchokera m'mimba. Zokwanira zomwe zimagwira mu plasma zimatheka pambuyo pafupifupi maola 2,5 pambuyo pakulowetsa. Ndizotheka kwambiri kuposa amoxicillin kumangiriza kumapulogalamu amwazi (mpaka 50%). Imasinthidwa mwachangu ku zimakhala zopezeka ndi phagocytes ndi neutrophils, zomwe zimapangitsa kuchuluka kwa mankhwalawa pano. Imagunda zotchinga za cytological, kulowa mkati mwa maselo.
Amoxicillin amalowa m'magazi mwachangu: kuchuluka kwa seramu kumapangidwira pambuyo pa maola 1.5 mukamamwa pakamwa ndi pambuyo pa ola limodzi ndikulowetsedwa mu minofu ya gluteus. Zodabwitsa za gawo loyamba sizikuwonedwa, bioavailability ukufika 90%. Amapangidwa pang'ono ndi chiwindi (osapitirira 20% ya kuchuluka koyamba), omwe amachotsa impso mkati mwa maola 3-4 kuyambira nthawi yogwiritsira ntchito.
Hafu ya moyo wa azithromycin ndi pafupifupi maola 65 chifukwa kubwezeretsanso matumbo panthawi yochotsa, komwe kumachepetsa pafupipafupi kumwa mankhwalawa. Achotseredwa makamaka ndi bile. Mphamvu ya antibacterial imatha osachepera masiku 5 pambuyo pa kumwa komaliza.
Contraindication yowonjezereka ya azithromycin ndiko kulephera kwa chiwindi. M'mapiritsi ndi mapiritsi, sayenera kuperekedwa kwa mwana ngati kulemera kwake kuli kochepera 45 kg. Malire a zaka zoyimitsidwa pakamwa ndi miyezi 6. Amoxicillin sinafotokozeredwe monocytic angina, matupi awo sagwirizana, chiwopsezo cha bronchospasm, rhinoconjunctivitis, lymphocytic leukemia, colitis ya mankhwala ndi magazi am'mimba. Ana ochepera zaka 10 akulimbikitsidwa kuti atengere mkati ngati kuyimitsidwa.
Kwa Amoxicillin, mbali yokhala ndi zotsatira zoyipa sizigwirizana, zomwe zimatha msanga atasiya kumwa mankhwalawo. Mankhwalawa angayambenso:
- matupi awo sagwirizana
- stomatitis
- kukokana
- tachycardia
- chinangwa
- kupweteka kwa anus,
- zilonda zam'mimba komanso magazi m'matumbo,
- kusakhazikika kwa matumbo microflora.
Dysbacteriosis ndi colitis ya mankhwala sadziwika ndi azithromycin. Amapereka zotsatira zochepa zosavomerezeka, koma zimatha kuyambitsa kuwonongeka kwambiri kwa chiwindi ndikuwonjezera kuchuluka kwa plasma kwa mankhwala omwe amamwa ndi shuga. Tengani kamodzi patsiku pang'ono. Amoxicillin amayenera kudyedwa kangapo patsiku, osasiya kumwa mankhwala kwa maola 48-72 atatha kutha kwa zizindikiro.
Ndibwino - Amoxicillin kapena Azithromycin?
Iliyonse ya mankhwalawa ili ndi zabwino komanso zovuta zake. Kuchita kwawo kumatengera kutengera kwa microflora ya bakiteriya. Chisankho chimapangidwa ndi adokotala, poganizira zotsutsana ndi zomwe wodwalayo ali nazo. Azithromycin ali ndi mawonekedwe owoneka ambiri, ali ndi zoletsa zochepa pakugwiritsa ntchito komanso mavuto. Koma ndi matenda ena, Amoxicillin amachita bwino.
Madokotala amawunika za Amoxicillin ndi Azithromycin
Svetlana, wazaka 40. Wothandizira, Kazan
Azithromycin ndiyotheka kugwiritsa ntchito komanso kulolera bwino. Chifukwa chokana kwambiri ndi beta-lactams, amoxicillin ikugwiritsidwa ntchito ngati gawo la othandizira.
Konstantin, wazaka 41, otolaryngologist, Moscow
Mankhwala onse awiri amatha kukhala othandiza polimbana ndi causative othandizira a tonsillitis, laryngitis, otitis media, sinusitis ndi zina zokhudzana ndi pathologies. Kutetezeka kwambiri kwa ana ndi azithromycin.