Analogs a makapisozi Xenical

Zina zamalonda zamankhwala: Xenical

Dzinalo Lopanda Padziko Lonse: Orlistat

Mlingo: makapisozi

Chithandizo: orlistat

Gulu la Pharmacotherapeutic: gastrointestinal lipase inhibitor

Katundu

Xenical ndi yoletsa yeniyeni ya lipases yam'mimba yokhala ndi zotsatira zokhalitsa. Zake zochizira zimachitika mu lumen pamimba ndi matumbo ang'onoang'ono ndipo amapangidwa pakupanga mgwirizano wolumikizana ndi gawo la serine la gastric ndi pancreatic lipases. Pankhaniyi, enzyme yovomerezeka imataya mphamvu yake yophwanya mafuta mu mawonekedwe a triglycerides kulowa mu mafuta aulere acids ndi monoglycerides. Popeza triglycerides yosasinthika simakhudzidwa, kutsika kwa kashiamu komwe kumapangitsa kuti thupi lichepe. Chifukwa chake, achire mphamvu ya mankhwalawa ikuchitika popanda kuyamwa mu zokhudza zonse kufalitsidwa.

Poona zotsatira za mafuta omwe ali mu ndowe, mphamvu ya orlistat imayamba patatha maola 24-48 atayamba kumwa. Pambuyo pakutha kwa mankhwalawa, mafuta omwe amakhala mumadzimbidwa pambuyo pa maola 48-72 nthawi zambiri amabwerera pamlingo womwe unachitika isanayambike mankhwala.

Zisonyezero zogwiritsidwa ntchito:

Njira yayitali yothandizira odwala omwe ali ndi kunenepa kwambiri kapena odwala onenepa kwambiri, kuphatikizapo okhala ndi zoopsa zomwe zimakhudzana ndi kunenepa kwambiri, kuphatikiza zakudya zamagulu ochulukitsa, kuphatikizapo mankhwala a hypoglycemic (metformin, zotumphukira za sulfonylurea ndi / kapena insulin) kapena kadyedwe koyenera ka odwala omwe ali ndi matenda a shuga 2 kapena onenepa kwambiri.

Zoyipa:

Matenda a malabsorption, cholestasis, hypersensitivity kwa mankhwala kapena zina zilizonse zili kapisozi.

Mlingo ndi makonzedwe:

Akuluakulu, mlingo woyenera wa orlistat ndi kapu imodzi ya 120 mg pachakudya chilichonse chachikulu (monga chakudya kapena osapitirira ola limodzi mutatha kudya). Ngati chakudya chidatsitsidwa kapena ngati chakudya mulibe mafuta, ndiye kuti Xenical imatha kudumphidwanso. Kuwonjezeka kwa mlingo wa orlistat pazowalimbikitsa (120 mg katatu patsiku) sikuti kumawonjezera pakuwonjezera kwake.

Kusintha kwa Mlingo kwa okalamba sikofunikira. Kusintha kwa Mlingo wa chiwindi kapena matenda a impso sikufunika. Chitetezo ndi luso la xenical mwa ana osakwana zaka 18 sizinakhazikitsidwe.

Zotsatira zoyipa:

Zotsatira zoyipa za orlistat zimachitika makamaka kuchokera m'matumbo am'mimba ndipo zimachitika chifukwa cha kupangika kwa mankhwala, zomwe zimasokoneza mayamwidwe akudya. Nthawi zambiri, zinthu monga kuchulukitsidwa kwamafuta kuchokera ku rectum, mpweya wokhala ndi zotulutsira zina, kufunikira kochotsa, kuwotcherera, kuchuluka kwa matumbo, zotulutsa zotayidwa, kupendekera, kupweteka m'mimba kapena kusasangalala.

Pafupipafupi zimachuluka ndikuwonjezera mafuta m'zakudya. Odwala ayenera kudziwitsidwa za kuthekera kwa mayankho ochokera m'mimba ndi kuphunzitsidwa momwe angachotsere mwa kudya bwino, makamaka poyerekeza kuchuluka kwa mafuta omwe amapezeka. Zakudya zamafuta ochepa zimachepetsa chiopsezo cha matenda am'mimba ndipo zimathandiza odwala kuwongolera komanso kuwongolera kudya mafuta.

Monga lamulo, izi zimachitika pang'onopang'ono komanso zofatsa. Amapezeka m'migawo yoyambirira yamankhwala (m'miyezi itatu yoyambirira), ndipo odwala ambiri sanatchulidwe kamodzi kachitidwe kameneka.

Mogwirizana ndi mankhwala ena:

Panalibe kuyanjana ndi amitriptyline, atorvastatin, biguanides, digoxin, fibrate, fluoxetine, losartan, phenytoin, njira zakulera pakamwa, phentermine, pravastatin, warfarin, nifedipine GITS (gastro-matumbo achire dongosolo) kapena nibbol-free, nibbol, freebb maphunziro amgwirizano pakati pa mankhwala osokoneza bongo). Komabe, ndikofunikira kuyang'anira momwe MNO imagwirira ntchito ndi warfarin kapena anticoagulants pakamwa.

Ndi makonzedwe apakati a xenical, kuchepa kwa mayamwidwe a mavitamini D, E ndi betacarotene kunadziwika. Ngati multivitamini akulimbikitsidwa, ayenera kumwedwa osachepera maola 2 mutatha Xenical kapena musanagone.

Ndi munthawi yomweyo makonzedwe a xenical ndi cyclosporine, kuchepa kwa plasma wozungulira wa cyclosporine, motero, kutsimikiza kwachulukidwe ka plasma cyclosporine mozungulira mukamatenga cyclosporine ndi xenical ndikulimbikitsidwa.

Ndi makonzedwe apakamwa a amiodarone panthawi yamankhwala am'mimba, kuchepa kwa mawonekedwe a amiodarone ndi desethylamiodarone adadziwika (pofika 25-30%), komabe, chifukwa cha zovuta za pharmacokinetics za amiodarone, kufunikira kwa zamankhwala pazinthu izi sikumveka. Kuphatikizidwa kwa xenical ku chithandizo chanthawi yayitali ndi amiodarone kungayambitse kuchepa kwa chithandizo chamankhwala a amiodarone (palibe maphunziro omwe adachitidwa).

Kukhazikitsa pamodzi kwa xenical ndi acarbose kuyenera kupewedwa chifukwa chosowa maphunziro a pharmacokinetic.

Ndi munthawi yomweyo makonzedwe a orlistat ndi antiepileptic, milandu ya kukomoka idawonedwa. Ubale wapakati pakati pa kukhazikika kwa khunyu ndi mankhwala a orlistat sunakhazikitsidwe. Komabe, odwala ayenera kuwunikidwa kuti azisintha pafupipafupi komanso / kapena kuopsa kwa matenda opatsirana.

Tsiku lotha ntchito: Zaka zitatu.

Mankhwala Okhala Pamalo a Pharmacy: mwa kulemba.

Mndandanda wa Magawo Omaliza a Xenical

Listata Mini (mapiritsi) Kutalika: 233 Pamwamba

Analogue ndiotsika mtengo kuchokera ku ma ruble 132.

Mpaka pano, Listata Mini ndiye phindu lalikulu kwambiri komanso lotsika mtengo la Xenical. Amapezeka mu mawonekedwe a piritsi ndipo ali ndi zomwe zimagwira, koma muyezo wotsika.

Orsotin Slim (makapisozi) Kukala: 195 Pamwamba

Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 18.

Orsoten Slim ndi cholowa m'malo mwa mitengo yoyenerana ndi Xenical. Kugulitsidwa m'makatoni a 42 kapena 84 makapisozi. Amawerengedwa kuti azigwiritsa ntchito kwa nthawi yayitali odwala omwe ali ndi chiwonetsero chachikulu cha thupi (BMI). Itha kuthandizidwa kuphatikizidwa ndi mankhwala a hypoglycemic komanso / kapena zakudya zochepa zopatsa mphamvu kwa odwala omwe ali ndi matenda a shuga a 2

Zochita zamankhwala

Xenical ndi zoletsa zamphamvu kwambiri zam'mimba zam'mimba. Zomwe zimapangidwa ndi makapisozi zimathandizira kusintha kwa kagayidwe ka mafuta mwanjira yoti mafuta osagawika a triglyceride amapangika panthawi ya mafuta. Izi zimasokoneza mayendedwe abwinobwino amadzi m'magazi. Momwe magazi amayendera samadwala, ndipo wodwala amayamba kuchepa.

Zochita za mankhwalawa zimayamba tsiku litatha kumwa. Izi zimatsimikiziridwa ndi mayeso olimbitsa thupi, momwe kuchuluka kwamafuta kumadziwika. Kuchotsera mankhwalawa m'malo mwake, kumathandizira kuchepetsa mafuta mu ndowe. Kafukufuku wachipatala akuwonetsa kukhudzika kwa mankhwalawa:

• Odwala ali ndi kuchepa kwakukulu kwa kulemera kwa thupi, poyerekeza ndi omwe anali pamankhwala amodzi okha.
• M'masabata awiri oyambilira atangoyamba kumene chithandizo, njira yokhazikika yamankhwala idakwaniritsidwa.
• Kuchepa kwamphamvu kwamankhwala kumawonedwa patatha zaka ziwiri atatha mankhwalawa, ngakhale atatha kuyankha molakwika pakudya.
• Chiwopsezo chowonjezeka thupi pambuyo mankhwala amachepetsedwa kwambiri.
• Kotala imodzi yokha mwa odwala onse omwe amathandizidwa amakhala ndi kuwonjezeka pang'ono kwa thupi.
• Mankhwala amachepetsa mwayi wokhala ndi glycemia mwa odwala matenda a shuga.

Zomwe zimayamwa ndikugawa mankhwalawa

Zachilengedwe zimachitika chifukwa cha Xenical thupi lonse ndizochepa. Palibe phindu lililonse lomwe ladziwika. Kamodzi m'thupi, limamangidwa ndi madzi am'magazi, kotero kuti mphamvu yake imangoyikika m'mimba. Xenical imapakidwa makamaka ndi ndowe zosasinthika. Kochepa kwambiri kamatsitsidwa ndi impso.

Zizindikiro ndi contraindication amatenga Xenical

Xenical akuwonetsedwa kuti agwiritse ntchito:

• Pankhani ya chithandizo chanthawi yayitali cha odwala onenepa kwambiri, makamaka ngati njira zochiritsira zimaphatikizidwa ndi thanzi la hypocaloric.
• Ngati kunenepa kwambiri kumathandizidwa ndi matenda a shuga limodzi ndi mapiritsi omwe amachepetsa shuga ya magazi.
• Ndi matenda a shuga a 2.
• Ngati njira zina zochizira kunenepa sizikugwira ntchito.

Xenical sichiloledwa:

• Matenda a malabsorption,
• Mitundu ikuluikulu ya kusayenda kwa ndulu,
• Hypersensitivity ya thupi ku zilizonse za mankhwala.

Mawonekedwe a Mlingo

Mankhwala akuwonetsedwa kuti azigwiritsidwa ntchito kwa odwala azaka zopitilira 12. Kugwiritsa ntchito odwala aang'ono sichinafotokozedwe. Mlingo wa mankhwalawa ndi kapisozi imodzi mwa 120 mg pa chakudya. Amaloledwa kugwiritsa ntchito Xenical ola limodzi mutatha kudya. Njira yomweyo yothandizira odwala omwe amamwa mankhwala a hypoglycemic.

Ndikofunikira kuti wodwala azikhala ndi zakudya zopatsa thanzi, komanso zopatsa mphamvu zopatsa mphamvu, komanso kuti zakudya za tsiku ndi tsiku ziyenera kukhala ndi mafuta osachepera 30 peresenti. Ndikofunikira kuti ma kilocalories amagawidwa mofananamo muzakudya za tsiku ndi tsiku.

Samalani: kuwonjezeka kwa njira yochizira sikukula. Milandu ya bongo wa mankhwala sichinachitike.

Palibe kuyanjana ndi ethanol komwe kunapezeka. Zinapezeka kuti mankhwalawa amachepetsa bioavailability a mavitamini A, D, E. Pakhala pali milandu ya kugwidwa pamene mumamwa mankhwala a antiepileptic. Muzochitika zonsezi, mankhwalawa ayenera kuikidwa mosamala.

Mutha kugula Xenical patsamba lathu pa mitengo yotsika mtengo!

Kutulutsa Fomu

KutiSenikal idapangidwa ndi a Swiss nkhawa Roche, koma mu 2017 ufulu wonse udapititsidwa ku kampani yopanga mankhwala yaku Germany a Chelapharm.

Wopezeka mu mawonekedwe a buluu No. 1 zolimba makapisozi. Pachikuto chake pali cholembedwa (chizindikiritso chakuda): "ROCHE", ndipo pamlanduwo - dzina la chinthu chachikulu: "XENICAL 120".

Makapisozi amawaikika mu zolumikizira zojambulazo za zidutswa 21 chilichonse. Ngati pali chithuza chimodzi pakatoni, amapatsidwa nambala 21.

Momwemo: matuza awiri mu phukusi - No. 42, matuza 4 - Ayi. 84 Palibe mitundu ina yotulutsira mankhwala omwe amadziwika.

Katundu wa mankhwala

Kukhazikitsa kwa kampani ndi kapisozi. Zomwe zili m'mawu ake ndi ma pellets: ozungulira oyera microsanules yoyera. Mwanjira imeneyi, kapisoziyu amalemera 240 mg. Iliyonse imakhala ndi 100 mg ya orlistat. Ichi ndiye chinthu chachikulu chopangira.

Makapisozi, kuwonjezera pa orlistat, ali ndi:

• ma cellcose a microcrystalline, omwe amagwira ntchito yopanga mafilimu - 93,6 mg,
• sodium wowuma glycolate ngati ufa wophika - 7.2 mg,
• povidone monga gawo lolumikizira kukhazikika kwa mawonekedwe a ma Microsanu - 12 mg,
• dodecyl sulfate, padziko lapansi yogwira. Amapereka kufulumira kwa ma pellets m'mimba - 7.2 mg,
• talc ngati filler ndi ufa wophika.

Chipolopolo cha kapisozi chimasungunuka kwathunthu m'mimba ndipo chilibe vuto lililonse. Muli ndi gelatin ndi mitundu yazakudya zotetezeka: indigo carmine (buluu wa buluu) ndi titanium dioxide (mwanjira ya granules yoyera).

Wopanga

Roche ndi amodzi mwa makampani apadziko lonse lapansi omwe akuchita nawo ntchito yopanga ndi kupanga mankhwala apadera kuti azindikire komanso kuthandizira matenda oopsa.

Roche (wamkulu ku Switzerland) ali ndi maudindo m'maiko opitilira 100 (kuyambira 2016).

Kampaniyi ili ndi ubale womwe wakhala ukugwirizana ndi Russia, omwe ali ndi zaka zopitilira 100. Masiku ano, malonda onse amakampani amaimiridwa ndi Rosh-Moscow CJSC.

Xenical: wogulitsidwa ndi mankhwala kapena ayi

Matenda a shuga amawopa mankhwalawa, ngati moto!

Muyenera kungolemba ...

Osagula mankhwalawo popanda mankhwala. Mutha kugulira mzawo wotsika mtengo, mwachitsanzo, Orlistat. Ngakhale ndi mankhwala omwe mumalandira.

Mukamagula Xenical muchipatala, tawonani kutentha kwa phukusi, kuyenera kukhala kozizira pakukhudza, popeza kusungidwa kwa mankhwalawa kumapereka mawonekedwe apadera a boma la 2-8 ° C

Kuphatikiza apo, bokosilo liyenera kukhala lolimba - lopanda mano kapena zolakwika zina. Paketi yodziwika, wopanga ayenera kuwonetsa tsiku lakapangidwe, moyo wa alumali ndi nambala ya batch. Mankhwala awa ndi piritsi. Chomwe chimachitidwira ndikuletsa ntchito ya lipase.

Uwu ndi puloteni imodzi yomwe imaphwanya kenako ndikugwira mafuta omwe amalowa m'thupi lathu. Pamene lipase “singagwire ntchito,” mafuta sasungidwa ndipo amachotsedweramo zinyalala. Zotsatira zake, thupi limakakamizidwa kuti ligwiritse ntchito nkhokwe za lipocyte m'mbuyomu. Chifukwa chake tikuchepetsa thupi.

Mankhwalawa adapangidwa kuti azilamulira kulemera kwa odwala omwe sanathandizidwe ndi kuwerengera kwa calorie mwanjira izi.

Ngati zakudya zokhazo zomwe dotolo amatha kupereka sizinaperekedwe, Xenical idalembedwa. Mankhwalawa amadziwika kuti ndi othandizira, chifukwa amasokoneza gawo logaya chakudya, ndipo munthu amachepetsa thupi mwakuchepetsa zomwe amapatsa zakudya zomwe amagwiritsa ntchito.

Mwachitsanzo, pakudya chidutswa cha nkhumba yokazinga ndi kumwa piritsi limodzi la mankhwalawo, mapuloteni okha ndi omwe amamwe. Mafuta onse, popanda chimbudzi, amachotsedwa pamimba. Chilichonse chikuwoneka ngati chodabwitsa. Koma ndikofunikira kumvetsetsa kuti Xenical sangathe kuchepetsa chilakolako cha kudya. Chifukwa chake, ngati munthu sakudziwa muyezo wa chakudya, mankhwalawo sangakhale wothandiza.

Opanga mankhwalawa sanayembekezere kuti mankhwalawa atha kumwa ndi anthu athanzi, inde. Kupatula apo, amapangidwira iwo omwe kunenepa kwambiri kwawopseza moyo. Kapena kwa iwo omwe ali ndi mavuto ndi kubereka kapena mawonekedwe. Chifukwa chake, funso: kumwa kapena osamwa Xenical, liyenera kuyankhidwa kokha ndi dokotala yemwe wayang'ana wodwala kwa nthawi yayitali.

Nthawi zambiri, mankhwalawa sagwiritsidwa ntchito ndi odwala omwe ali ndi kunenepa kwambiri, koma amayi oonda. Pankhaniyi, makapisozi saledzera pafupipafupi, koma kamodzi, monga mapiritsi a phwando.

Koma lero palibe ziwerengero zokhudzana ndikuyenda bwino ndi chitetezo chamtundu umodzi wokha.

Sizikumveka kwathunthu momwe pulogalamu yanu yazakudya imayankhira chithandizo chotere. Osamaika pangozi thanzi lanu ndikulembera ena mapiritsi. Muyenera choyamba kuyendera katswiri wazakudya yemwe amafufuza moyenera thanzi lanu komanso zomwe zingachitike.

Xenical idapangidwira iwo omwe akudziwa zamagulu oyenera kudya, ndipo amathandiza ngati wodwala wadutsa pulogalamu yayitali yochepetsa thupi. Mfundo zoyeserera mankhwalawa ndizosavuta: kutsatira zakudya zomwe zaperekedwa ndikuwerengera zopatsa mphamvu. Ngati simungathe kukana - pezani piritsi. Koma mtsogolomo, tsatirani zakudya zomwe mwawoneazo.

Kumbukirani kuti kuchepa thupi kokha chifukwa cha Xenical sikungathandize. Komabe, muyenera kusiya moyo wam'mbuyomu ndikusintha kadyedwe.

Muyenera kukonzekera kutenga makapisozi: masiku 10 isanayambike mankhwala, muyenera kusinthira moyenera ku chakudya chochepa chopatsa mphamvu ndikuwonjezera zolimbitsa thupi.

Nthawi imeneyi, thupi limasintha ndikusintha kwatsopano, ndipo Xenical imachita bwino kwambiri. Zakudya zoyenera ziyenera kukhala ndi mapuloteni 15%, pafupifupi 30% mafuta. Zina ndizophatikiza ndi chakudya.Muyenera kudya pang'ono, nthawi 5-6 patsiku.

Madyerero atatu adzakhala amodzi, awiri - apakatikati, ndipo usiku ndi bwino kumwa chinthu chopatsa mphamvu. Pa maziko a chakudyacho muyenera kukhala chakudya chovuta kupukusa chakudya: mkate wamphesa, chimanga, masamba ndi pasitala. Kuchepetsa thupi kumakhudzana mwachindunji ndi kuchuluka kwa mafuta omwe amamwetsa: 1 g yamafuta amafanana ndi 9 kcal.

Kutengera kwa Xenical nthawi yomweyo, kudya komanso kuchita masewera olimbitsa thupi kumathandizira:

• Matenda a magazi,
• kuchotsa "choyipa" cholesterol,
• kukhazikika kwamisempha ya insulin,
• mtundu 2 kupewa matenda ashuga.

Musaiwale za zolimbitsa thupi. Ndi gawo limodzi la chithandizo chamankhwala. Kuchita zolimbitsa thupi moyenera komanso mosalekeza kudzakuthandizani kuchotsa madipoziti ambiri m'malo ovuta: pamimba ndi m'chiuno.

Aliyense amene adaganiza zochepera thupi amasangalatsidwa ndi funso: mtengo wa Xenical ndi chiyani, ulipo? Pansipa pali chithunzithunzi cha mtengo wa mankhwalawa (ma ruble) a zigawo zosiyanasiyana za dziko lathu.

Moscow ndi dera:

• makapisozi No. 21 - 830-1100,
• makapisozi No. 42 - 1700-2220,
• makapisozi No. 84 - 3300-3500.

St. Petersburg ndi dera:

• makapisozi No. 21 - 976-1120,
• makapisozi No. 42 - 1970-2220,
• makapisozi No. 84 - 3785-3820.

Samara:

• makapisozi No. 21 - 1080,
• makapisozi No. 42 - 1820,
• makapisozi No. 84 - 3222.

Vladivostok:

• makapisozi No. 21 - 1270,
• makapisozi No. 42 mpaka 2110.

Kuphatikiza pa mankhwala oyamba a ku Switzerland, mankhwala ake omwe amakhalanso akugulitsidwa. Amakhala ndi zochizira zofanana ndi Xenical, koma malingaliro pazomwe amachita ndi osiyana kwambiri. Analogs ali ndi mayina awo, amapezeka m'mitundu yosiyanasiyana: ufa, kapisozi kapena mapiritsi.

Tiyenera kumvetsetsa kuti popeza wopanga mankhwala ofananawo sanachitepo mayeso okwera mtengo ndipo sanawononge ndalama pakukula, mtengo wawo umakhala wotsika kwambiri kuposa mankhwala oyambirirawo.

Makanema okhudzana nawo

Ndemanga kanema wa mankhwala ochepetsa Xenical:

Xenical adapangira anthu omwe ali ndi vuto lalikulu la kunenepa kwambiri. Ichi ndi mankhwala, ndiye kuti, ndi dokotala yekhayo amene ayenera kumwa mankhwala. Adziwitsanso njira ya mankhwalawa komanso mlingo woyenera.

Xenical siyabwino kwa iwo omwe adangoganiza kuti angotaya mapaundi owonjezera. Kuti muchite izi, ingoyesani pang'ono: idyani mafuta ochepa ndikupita kumasewera.