Malangizo a Pulatifiti a Glformin ogwiritsira ntchito

Mankhwalawa "Glyformin" 1000 mg, komanso mitundu ina ya mankhwalawa, amagwiritsidwa ntchito pochepetsa shuga ya magazi ndi chithandizo cha matenda a shuga 2. Mankhwalawa amadziwika kuti ndi amodzi aothandiza kwambiri kwa shuga wambiri, koma ali ndi zotsutsana zingapo komanso chizindikiro cham'mbali, chifukwa chake ndikofunikira kufunsa dokotala musanagwiritse ntchito.

ZOFUNIKA KUDZIWA! Ngakhale odwala matenda ashuga kwambiri amatha kuchiritsidwa kunyumba, popanda opaleshoni kapena zipatala. Ingowerenga zomwe Marina Vladimirovna akunena. werengani zonena zake.

Kuphatikizika, mawonekedwe omasulidwa

Mankhwala "Glformin" amapangidwa mwanjira ya mapiritsi amthunzi wopepuka. Mapangidwe a piritsi 1 ali ndi 500, 800 kapena 1000 mg pazinthu zomwe zimagwira ntchito ya metformin. Omwe amathandizira - calcium dihydrate, magnesium stearate, povidone ndi sorbitol. Mapiritsi a Glyformin amapezeka m'matumba a zidutswa 10 ndipo amadzaza mabokosi.

Shuga amachepetsedwa nthawi yomweyo! Matenda a shuga m'kupita kwa nthawi angayambitse matenda ambiri, monga mavuto amawonedwe, khungu ndi tsitsi, zilonda zam'mimba, zilonda zam'mimba komanso matenda otupa! Anthu amaphunzitsa zinzake zowawa kuti azisintha shuga. werengani.

Njira yamachitidwe

Zinthu zomwe zimagwira, zomwe ndi gawo la Glformin, zimalepheretsa shuga kupanga chiwindi ndikuyambitsa kupasuka kwake. Mankhwalawa amathandizira kuchepetsa kuchuluka kwa triglycerides ndi cholesterol m'magazi am'magazi, chifukwa chomwe amachepetsa chilakolako cha odwala. Pogwiritsa ntchito zinthu izi za mankhwalawa, ndizotheka kuchepetsa thupi, zomwe ndizofunikira kwambiri kwa odwala omwe ali ndi kunenepa kwambiri. Kuphatikiza apo, mankhwalawa amasungunuka magazi, omwe amachepetsa mwayi wophatikizana ndi maplatelet.

Zizindikiro zogwiritsidwa ntchito

Malinga ndi malangizo ogwiritsira ntchito, mankhwalawa "Glyformin Prolong" amagwiritsidwa ntchito motere:

• lembani matenda a shuga a 2 shuga, momwe zakudya zomwe zimapezeka sizingathandize,
• mankhwalawa a mtundu 1 matenda a shuga monga gawo la zovuta mankhwala a insulin.

Malangizo ogwiritsira ntchito ndi kumwa kwa "Glformina Pronge"

Mlingo wa mankhwalawa umakhazikitsidwa ndi katswiri wozika zisonyezo za shuga mthupi. Monga tafotokozera mu malangizo ogwiritsira ntchito, gawo loyamba la chithandizo limaphatikizapo kugwiritsa ntchito 1 g ya "Glformin Prolong" patsiku. Kuwonjezeka kwina kwa zovomerezeka pambuyo pa masabata awiri. Mlingo waukulu patsiku suyenera kupitirira 3 g ya mankhwalawa. Kwa odwala okalamba, mlingo waukulu patsiku suyenera kupitirira 1 g.

Contraindication

Glyformin Prolong mankhwala othandizira salembetsedwa ngati wodwala ali ndi izi:

• ketoacidosis
• chikomokere
• Kulakwitsa kwa impso,
• Njira zochizira zomwe zimaphatikizapo kugwiritsa ntchito insulin,
• mavuto ndi chiwindi,
• uchidakwa
• kuledzera kwa thupi ndi mowa,
• lactic acidosis
• Kutsatira zakudya zamafuta, zomwe cholinga chake ndikuchepetsa mwamphamvu ma calories,
• nthawi yapakati
• kuyamwitsa
• tsankho limodzi ndi zigawo zikuluzikulu za mankhwala.

Zotsatira zoyipa

Malangizo ogwiritsa ntchito akuti mankhwalawa "Glyformin Prolong" angayambitse zizindikiro zoyipa:

1. Matumbo:
   • kulumikizana
   • kulawa kwazitsulo pamkamwa,
   • kusowa kwa chakudya
   • matenda amkuwa
   • kuchuluka kupatukana kwa mpweya
   • kupweteka m'matumbo.
2. Ziwalo za Hematopoietic:
   • megaloblastic anemia.
3. Zambiri:
   • zotupa pakhungu,
   • hypoglycemia.

"Gliformin" wambiri

Malangizo ogwiritsira ntchito akuti kuchuluka kwa "Gliformin" nthawi zina kumayambitsa hyperlactacidemic kapena lactic acid chikomokere, komwe kumabweretsa imfa. Zizindikiro zoyambirira za lactic chikomokere:

• kulumikizana
• akukumbutsa
• kutsegula m'mimba
• kutopa
• kutsitsa kutentha kwa thupi
• m'mimba kukokana
• kupweteka kwa minofu
• kutsika kwa magazi.

Ngati wodwala ali ndi zomwe tafotokozazi pamwambapa, ndikofunikira kusiya kugwiritsa ntchito Glformin nthawi yomweyo. Wodwalayo amatumizidwa kuchipatala komwe maphunziro onse ofunikira amachitidwa ndikuwonetsa koyambirira kumatsimikiziridwa kapena kutsimikiziridwa. Izi zimatsatiridwa ndi chithandizo chamankhwala, chomwe cholinga chake ndi kusiya zizindikiritso zomwe zidatulukira.

M'mikhalidwe yovuta kwambiri, kuyeretsa magazi koonjezera kumachitika.

Kuyanjana kwa mankhwala osokoneza bongo

Kugwiritsa ntchito kwa angiotensin kutembenuza ma enzyme inhibitors, mankhwala osokoneza bongo a anti-yotupa, insulin, beta-blockers ndi sulfonylureas kumayambitsa kuwonjezeka kwa Glyformin, yomwe ikufuna kuchepetsa magazi. Kutumiza munthawi yomweyo mankhwala opangidwa ndi mankhwala ophatikizidwa ndi glucocorticoids, mahomoni a chithokomiro, mankhwala okodzetsa a gulu la thiazide komanso njira zakulera zapakamlomo zimathandizira kuchepa kwa mphamvu ya hypoglycemic ya Glyformin.

Tchuthi ndi malo osungira

Mutha kugula mankhwalawa "Glyformin" a shuga m'matumbo a mankhwala okha ndi mankhwala a katswiri wovomerezeka yemwe ali ndi chisindikizo choyenera. Ndikofunika kusunga mankhwalawo pamalo owuma momwe mumakhala kutentha kwapakati ndipo palibe mwayi wowongolera dzuwa. Mankhwalawa amasungidwa, monga akuwunikira mu malangizo, sangathe kupitirira zaka 3 kuchokera tsiku lomwe adapanga. Tsiku lotha litatha, kumwa mankhwalawo ndizoletsedwa kuti tipewe zovuta.

Mitu ya mankhwalawa

Mankhwala otsatirawa amatengedwa kuti ndi mankhwala akuluakulu omwe amawonedwa kuti ndi fanizo la Gliformin:

Ogwira ntchito zachipatala amadziwa kuti mankhwala aliwonse ali ndi zake zomwe zimagwiritsidwa ntchito komanso zizindikiro zingapo zoyipa. Ichi ndichifukwa chake amaletsedwa mwamphamvu kusintha mankhwala omwe adokotala amupatsa kuti athandize odwala matenda ashuga, kuti asayambitse zovuta komanso zotsatirapo zoyipa. Ndi matenda a shuga, ndikofunikira kutsatira mosamala malingaliro a katswiri.

Kodi zikuwonekabe zosatheka kuchiritsa matenda ashuga?

Poona kuti mukuwerenga izi tsopano, kupambana polimbana ndi shuga wambiri sikuli kumbali yanu.

Ndipo mudaganizapo kale za chithandizo kuchipatala? Ndizomveka, chifukwa matenda ashuga ndi matenda oopsa, omwe, ngati sanapatsidwe, amatha kufa. Udzu wokhazikika, kukodza mwachangu, masomphenya osalala. Zizindikiro zonsezi mumazidziwa nokha.

Koma kodi ndizotheka kuchitira zomwe zimayambitsa m'malo mothandizira? Timalimbikitsa kuwerenga nkhani yokhudza matenda aposachedwa a shuga. Werengani nkhani >>

Kugwiritsa

Glyformin Pronge amalimbikitsa kugwiritsidwa ntchito kwa glucose ndi minofu, amachepetsa kuyamwa kwa matumbo m'matumbo. Komanso, mankhwalawa amathandizira chidwi cha zimakhala kuti insulin.

Zizindikiro zazikulu zogwiritsira ntchito mankhwalawa:

• Type 2 shuga mellitus. Amagwiritsidwa ntchito ngati chakudya kapena zolimbitsa thupi sizinabweretse zotsatira zomwe mukufuna.
• Mtundu woyamba wa shuga. Ntchito ngati cholumikizira insulin.

Kwa monotherapy. Gwiritsani ntchito ndi mankhwala ena omwe ali ndi vuto lofananalo kuloledwa.

Mankhwalawa saloledwa kugwiritsidwa ntchito popanda kupimidwa kuchipatala: Malangizo a glyformin ogwiritsira ntchito akuwonetsa zingapo zotsutsana.

Chithandizo cha Gliformin ndichitali. Pa mankhwala, muyenera kumachita mayeso omwe akuwonetsa zomwe zikuchitika pakhungu ndi impso. Asanakhale mayeso, muyenera kusiya kumwa mankhwalawa kwa maola osachepera 48. Ngati simutsatira lamuloli, ndiye kuti zotsatira zoyesa zingakhale zolakwika. Mankhwala amaloledwa kuyambiranso masiku angapo pambuyo pa njirazi.

Samaloledwa kumwa mowa wambiri panthawi ya chithandizo. Muyeneranso kupewa mankhwala okhala ndi Mowa.

Komanso, maphunziro sanachitidwe kwa ana osakwana zaka 18. Munthawi imeneyi, mankhwalawa amayenera kumwedwa mosamala, motsogozedwa ndi achipatala mosalekeza.

Glformin Prolong siyikulimbikitsidwa kuti muchepetse thupi, kupatula kukayikiridwa kuti akupanga matenda ashuga.

The zikuchokera, mlingo mawonekedwe, analogues

Mankhwala Glformin Prolong, kampani yaku Russia ya mankhwala Akrikhin, amatulutsa mapiritsi okhala ndi mafilimu okhala ndi mphamvu yotulutsa.

Piritsi lililonse la chikasu la biconvex limakhala ndi 750 mg yogwira ntchito ya metformin hydrochloride ndi zotulukazo: silicon dioxide, hypromellose, cellcrystalline cellulose, magnesium stearate.

Mapiritsi okhala ndi 30 kapena 60 ma PC. mu pensulo yonyamula pulasitiki yokhala ndi cholembera ndi kuteteza chitetezo pakutsegulira koyamba. Pulasitiki yonyamula imayikidwa mu katoni. Alumali moyo wa mankhwalawa pamalo owuma, amdima firiji ndi zaka 2. Kwa Gliformin Prolong 1000, mtengo pa intaneti umachokera ku ma ruble 477.

Ngati mukufuna m'malo mankhwalawa, adokotala amatha kugwiritsa ntchito fanizo ndi mankhwala omwewo:

• Fomu
• Metformin
• Glucofage,
• Metformin Zentiva
• Glformin.

Zamankhwala a Gliformin

Mankhwala Glformin Prolong amawerengedwa kuti amachepetsa shuga mu gulu la Biguanide. Dimethylbiguanide bwino basal ndi postprandial glycemia. Amayendedwe a metformin, chinthu chofunikira cha formula, ndikuthandizira chidwi cha zotumphukira za maselo a cell kuti azikhala ndi insulini komanso kuti azigwiritsa ntchito kuthamanga kwa glucose mu minofu minofu.

Mankhwalawa sakukhudza kupanga kwa amkati a insulin, chifukwa chake palibe hypoglycemia pakati pazotsatira zosayenera. Kuletsa gluconeogeneis, metformin imalepheretsa kuphatikiza kwa shuga m'chiwindi ndikulepheretsa mayamwidwe ake m'matumbo. Pogwiritsa ntchito glycogen synthase mwachangu, mankhwalawa amathandizira kupanga glycogen, imapangitsa luso la mayendedwe amtundu uliwonse wamagulu onyamula shuga.

Pharmacokinetics

Atatha kudya mapiritsi awiri a Glformin Prolong (1500 mg), imafika pakuloweka kwambiri m'magazi pambuyo pa maola pafupifupi asanu. Ngati tikufanizira kuchuluka kwa mankhwalawa pakapita nthawi, ndiye kuti mlingo umodzi wa 2000 mg wa metformin wokhala ndi mphamvu yayitali ikufanana pakukwaniritsidwa kawiri kugwiritsa ntchito metformin ndikumasulidwa kwachizolowezi, omwe amatengedwa kawiri patsiku kwa 1000 mg.

Kapangidwe ka chakudya, komwe kamatengedwa limodzi, sikukhudza kuyamwa kwa mankhwala Glyformin Prolong. Pogwiritsa ntchito mapiritsi kawiri kawiri pa 2000 mg, kuchuluka kwake sikumakhazikika.

Mankhwalawa amamangirira pang'ono pamapuloteni amwazi. Kugawa voliyumu - mkati mwa 63-276 l. Metformin ilibe ma metabolites.

Mankhwalawo amachotsedwa mu mawonekedwe ake oyambirira m'njira yachilengedwe mothandizidwa ndi impso. Pambuyo ingestion, kuchotsa theka moyo si upitirire 7 maola. Ndi kukanika kwa aimpso, theka la moyo limatha kukula ndikuthandizira kuti pakhale kuchuluka kwa metformin m'magazi.

Zizindikiro za gliformin yotalikilapo

Mankhwalawa adapangira kuti azilamulira matenda a shuga a mtundu wa 2, makamaka kwa anthu okalamba onenepa kwambiri, ngati kusintha kwa moyo kulibe kubwezera 100% glycemic.

Mankhwalawa amagwiritsidwa ntchito onse mu monotherapy komanso panjira yovuta kutsata ndi mapiritsi ena a antidiabetes kapena insulin nthawi iliyonse yamatendawa.

Glyformin pa mimba

Pobweza pang'ono mtundu wa matenda ashuga a 2, mimbayo imapitirira ndi ma pathologies: kusokonezeka kwa kubadwa, kuphatikizanso kufa kwa pathupi, ndizotheka. Malinga ndi malipoti ena, kugwiritsa ntchito metformin sikuti kumayambitsa kusintha kwa kubereka mwa mwana wosabadwa.

Komabe, pa gawo lokonzekera kubereka, ndikofunika kusintha kuti mukhale ndi insulin. Pofuna kupewa kupatuka kwa mwana, ndikofunikira kuti amayi apakati azilamulira glycemia ndi 100%.

Mankhwala amatha kulowa mkaka wa m'mawere. Ndipo ngakhale kuti palibe zoyipa zomwe zimayambitsa makanda omwe akuyamwitsa, Glformin Pronge silipereka malangizo oti mugwiritse ntchito mukamayamwa. Lingaliro la kusinthira pakudya kwachilendo limapangidwira poganizira zovuta zomwe zingavulaze mwana ndi mapindu ake mkaka wa amayi.

Momwe mungagwiritsire ntchito moyenera

Kutalika kwa Glyformin kumapangidwira ntchito zamkati. Piritsi imatengedwa kamodzi - madzulo, ndi chakudya chamadzulo, popanda kutafuna. Mlingo wa mankhwalawa amatsimikiziridwa ndi dokotala, poganizira zotsatira za mayeso, gawo la matenda ashuga, zomwe zimayenderana ndi zomwe zimachitika, zomwe zimachitika komanso momwe munthu amvera mankhwalawo.

Monga mankhwala oyambira, ngati munthu wodwala matenda ashuga sanamwe mankhwala a metformin, tikulimbikitsidwa kuti muyezo woyamba wa mankhwalawa udalowe mkati mwa 750 mg / tsiku, kuphatikiza kumwa mankhwalawo ndi chakudya. M'masabata awiri ndizotheka kuwerengera bwino momwe mankhwalawo adasankhidwira ndipo ngati ndi kotheka, musinthe. Kuchepetsa kucheperachepera kwa muyezo kumathandizira kuti thupi lizisintha mosavutikira komanso kuchepetsa kuchuluka kwa zovuta.

Mulingo wamba wamankhwala ndi 1500 mg (mapiritsi 2), omwe amamwa kamodzi. Ngati simungathe kukwaniritsa momwe mungafunikire, mutha kukulitsa kuchuluka kwa mapiritsi mpaka 3 (iyi ndi mlingo waukulu). Amatengedwa nthawi yomweyo.

Momwe mungagwiritsire ntchito: Mlingo ndi njira ya chithandizo

Mapiritsi a Glyformin Prolong amatengedwa pakamwa, kumezedwa kwathunthu, osafuna kutafuna, ndimadzi okwanira, 1 nthawi patsiku mkati mwakudya kapena mutatha kudya. Mlingo wa mankhwalawa amasankhidwa ndi dokotala payekhapayekha kwa wodwala aliyense potengera zotsatira za kuyeza kuchuluka kwa shuga m'magazi.

Monotherapy ndi kuphatikiza mankhwalawa kuphatikiza othandizira ena a hypoglycemic

Kutembenuka kuchokera ku Metformin kupita Kumasulidwe Nthawi Zonse

Glyformin Prolong imafotokozedwa ngati mankhwala ochiritsira kwa odwala omwe amamwa metformin mwa mapiritsi ndi kutulutsidwa kwazonse pa mlingo wa 1000 mg kapena 2000 mg. Mukamasintha metformin yokhazikika, mlingo wa tsiku ndi tsiku uyenera kukhala wofanana ndi mtundu wa metformin watsiku ndi tsiku. Odwala omwe amatenga metformin mu mawonekedwe a mapiritsi omwe ali ndi chizolowezi chomasulidwa muyezo wopitilira 2000 mg osavomerezeka amasinthidwa kupita ku Glyformin Prolong.

Kukhazikitsa kwa odwala kale osamwa metformin

Odwala osamwa metformin, mankhwala oyambira omwe amapezeka kwa nthawi yayitali ndi 500 mg kapena 750 mg kamodzi tsiku lililonse pa chakudya. Pakadutsa masiku 10 mpaka 10, tikulimbikitsidwa kusintha kagayidwe kake kamene kamayambira pazotsatira za kuchuluka kwa shuga m'magazi am'magazi, ndikusintha kwa mankhwalawa panthawi ya 1000 mg. Kuwonjezeka pang'onopang'ono kwa mankhwalawa kumathandiza kuchepetsa zovuta kuchokera m'matumbo am'mimba.

Kusintha kuchokera ku mankhwala ena a hypoglycemic

Pankhani ya kusintha kuchokera kwa wothandizila wina wa hypoglycemic, kusankha kwa mankhwalawa kumachitika monga momwe tafotokozera pamwambapa, kuyambira poyang'anira metformin wa 500 mg kapena 750 mg wambiri.

Kukwaniritsa bwino glycemic control, metformin ndi insulin zingagwiritsidwe ntchito pophatikiza mankhwala.Mlingo woyamba wa metformin womwe umatulutsidwa kwa nthawi yayitali ndi piritsi limodzi la 500 mg kapena 750 mg kamodzi patsiku chakudya chamadzulo, pamene mlingo wa insulin umasankhidwa potengera zotsatira za kuyeza kuchuluka kwa shuga m'magazi. Kupitilira apo, kusintha kwa mlingo wa metformin 1000 mg ndikotheka.

Mlingo woyenera kwambiri wa Glyformin Pronge ndi mapiritsi 2 patsiku (2000 mg). Ngati glycemic yaukwanira siyikwaniritsidwa ndi kuchuluka kwa mankhwalawa omwe amakulimbikitsidwa tsiku lililonse, ndikotheka kusinthana ndi metformin ndikumasulidwa kwawonekera ndi mlingo waukulu wa tsiku 3000 mg.

Ngati mukuphonya mlingo wotsatira, wodwalayo ayenera kumwa mlingo wotsatira panthawi yokhazikika. Osamwa kawiri mlingo wa mankhwalawa.

Kutalika kwa mankhwala

Mankhwalawa ayenera kumwedwa tsiku lililonse, osasokoneza. Ngati chithandizo chalekeka, wodwalayo ayenera kudziwitsa dokotala.

Okalamba odwala ndi odwala omwe ali ndi vuto laimpso

Okalamba odwala ndi odwala mkhutu aimpso ntchito, mankhwalawa amasinthidwa malinga ndi kuwunika kwa aimpso, omwe amayenera kuchitidwa pafupipafupi.

Kutulutsa mawonekedwe ndi kapangidwe kake

Gliformin imapezeka mu mawonekedwe a mapiritsi a 500 mg a yogwira mankhwala metformin hydrochloride ndi mapiritsi okhala ndi mafilimu, a 850 ndi 1000 mg a yogwira.

Mapiritsi a 500 mg ndi osalala-cylindrical, oyera kapena pafupifupi oyera. Pamwamba pali chiopsezo ndi chamfer. Zidutswa 10 zimapangidwa m'matumba a blister. Paketi imodzi yamakatoni mumakhala mapaketi 6.

Mapiritsi okhala ndi mafilimu ndi biconvex, oval, oyera. Imvi kapena zonona zimaloledwa. Zidutswa 60 zimapangidwa muzimbe za polypropylene kapena polyethylene. Phukusi limodzi lokhathamiritsa lili ndi 1 akhoza.

Zomwe zimapezeka mu mapiritsi a Gliformin 500 mg ndi izi:

• Calcium calcium phosphate dihydrate,
• Macrogol (polyethylene glycol),
• Sorbitol
• Povidone (polyvinylpyrrolidone),
• Stearic acid (kapena calcium calcium).

Zinthu zothandiza pamapiritsi a Glformin 850 ndi 1000 mg ndi izi:

• Povidone (polyvinylpyrrolidone),
• Wowuma wa mbatata
• Stearic acid.

Kuphatikizika kwa mafilimu kumakhala ndi macrogol (polyethylene glycol 6000), hypromellose (hydroxypropyl methylcellulose) ndi talc.

Kusinthidwa kwa othandizira ena a hypoglycemic omwe ali ndi Glformin Pronge

Ngati munthu wodwala matenda ashuga atenga kale mankhwala opangidwa ndi Metformin omwe ali ndi mphamvu yotulutsidwa, ndiye kuti mukawachotsa ndi Glformin Prolong, wina ayenera kuganizira za kumwa kwa tsiku lililonse. Ngati wodwala amatenga metformin pafupipafupi muyezo wa 2000 mg, kusintha kwa glyformin kwakanthawi sikokwanira.

Ngati wodwalayo adagwiritsa ntchito othandizira ena a hypoglycemic, ndiye kuti mukachotsa mankhwalawo ndi Glformin Pronge amawongoleredwa ndi muyezo.

Metformin yamtundu wa 2 shuga imagwiritsidwanso ntchito limodzi ndi insulin. Mlingo woyambira wa Glyformin Prolong ndi zovuta mankhwala ndi 750 mg / tsiku. (phwando limodzi lophatikizidwa ndi chakudya chamadzulo). Mlingo wa insulin amasankhidwa poganizira zomwe amawerengera a glucometer.

Mlingo wovomerezeka wazomwe zimakhala ndi nthawi yayitali ndi 2250 mg (3 ma PC.). Ngati matenda ashuga sangakwanitse kuwongolera kwathunthu matendawa, amawasinthira mtundu wamankhwala ndikumasulidwa kwachizolowezi. Mwa njira iyi, mlingo waukulu ndi 3000 mg / tsiku.

Kutalika kwa maphunzirowa kumatengera ndi kupezeka kwa mankhwalawa: ngati ma polycystic ovary omwe ali ndi metformin nthawi zina amatha kuchiritsidwa mwezi, ndiye kuti odwala matenda ashuga omwe ali ndi matenda 2 amatha kutenga moyo wonse, kuwonjezera njira yothandizira mankhwalawa pogwiritsa ntchito mankhwala ena ngati kuli kofunikira. Ndikofunika kumwa mankhwalawo nthawi yomweyo, tsiku ndi tsiku, osasokoneza, osayiwala zakuwongolera kwa shuga, Zakudya zama carb ochepa, zolimbitsa thupi, komanso zochitika zam'maganizo.

Malangizo a magulu enieni a ashuga

Kwa mavuto a impso, mtundu wautaliwu sulembedwera mitundu yokhayo yamatenda, pomwe creatinine chilolezo chotsika kuposa 45 ml / min.

Mlingo woyambira wa odwala matenda ashuga a impso ndi 750 mg / tsiku, malirewo afika pa 1000 mg / tsiku.

Kuchita bwino kwa impso kuyenera kuwunikidwa pafupipafupi kwa miyezi 3-6. Ngati chilengedwe cha creatinine chatsika pansi pa 45 ml / min., Mankhwalawo amachotsedwa mwachangu.

Mukulu, pamene mphamvu ya impso yafupika kale, titration ya mlingo wa Glformin Prolong imachitika pamaziko a mayeso a creatinine.

Zotsatira zoyipa

Metformin ndi imodzi mwamankhwala otetezeka kwambiri omwe amayesedwa nthawi ndi maphunziro ambiri. Kapangidwe ka zotsatira zake sikulimbikitsa kupanga kwa insulin yake, chifukwa chake, hypoglycemia nthawi ya monotherapy sichimapangitsa kuti Glyformin Prolong ikhale. Chochitika chovuta kwambiri ndizovuta zam'mimba, zomwe zimatengera umunthu wa thupi ndikupita pambuyo pozolowera popanda chithandizo chamankhwala. Kukula kwa zoyambitsa kumawunikidwa malinga ndi kuchuluka kwa WHO:

Zotsatira zakuwonera zikuwonetsedwa mu tebulo.

Kugwiritsira ntchito nthawi yayitali kwa Glyformin Prolong kumatha kuyambitsa kuwonongeka kwa vitamini B12. Ngati matenda am'madzi a megaloblastic atapezeka, ayenera kulumikizidwa ku etiology yomwe ingatheke.

Kuti muchepetse kuwonetseredwa kwa vuto la dyspeptic, piritsi imatengedwa bwino ndi chakudya.

Hepatic insuffidence, yomwe imakwiya ndi kugwiritsa ntchito Glformin, imazimiririka yokha ikatha kulandira mankhwalawo.

Ngati izi zasintha m'matenda atatha kumwa Glyformin Prolong, wodwalayo ayenera kuchenjeza adokotala omwe amapezekapo.

Zizindikiro zochuluka

Mukamagwiritsa ntchito 85 g ya metformin (mlingo umakulitsa wowonjezera nthawi 42,5), hypoglycemia sizinachitike. Zikatero, lactic acidosis inayamba. Ngati wozunzidwayo adawonetsa zofanana ndi zomwe zikuchitika, kugwiritsa ntchito Glformin Prolong kumatha, wodwalayo amalizidwa kuchipatala, mulingo wa lactate ndikuwunikira kumveka. Metformin yowonjezera ndi lactate zimachotsedwa ndi dialysis. Mofananamo, chithandizo chamankhwala chimachitika.

Kuphatikiza kophatikizidwa

Zizindikiro zosiyanitsa ndi X-ray, zomwe zimakhala ndi ayodini, zimatha kuyambitsa lactic acidosis mu matenda ashuga omwe amakhala ndi vuto la impso. M'mayeso ogwiritsa ntchito mankhwalawa, wodwalayo amamuika insulin masiku awiri. Ngati impso ili yokhutiritsa, patatha masiku awiri mutawerengedwa, mutha kubwerera ku regimen yapita.

Maofesi olimbikitsidwa

Ndi poyizoni wa mowa, mwayi wa lactic acidosis ukuwonjezeka. Amawonjezera mwayi wa zakudya zochepa zopatsa mphamvu, kuperewera kwa chiwindi. Mankhwala opangidwa ndi Ethanol amakhumudwitsa chimodzimodzi.

Zosankha kukhala osamala

Mukamagwiritsa ntchito mankhwala osagwiritsidwa ntchito ndi hyperglycemic effect (glucocorticosteroids, tetracosactide, β-adrenergic agonists, danazole, diuretics), kuyang'anira kuchuluka kwa magazi ndikofunikira. Malinga ndi zotsatira za glucometer, mlingo wa Glyformin Prolong umasinthidwanso. Ma diuretics amayambitsa mavuto a impso, ndipo, chifukwa chake, lactic acidosis.

Mankhwala a antihypertensive amatha kusintha zizindikiro za hypoglycemic. Ndi munthawi yomweyo, kupatsidwa mlingo wa metformin ndizovomerezeka.

Ndi chithandizo cha kufanana ndi insulin, acarbose, mankhwala a sulfonylurea, salicylates, Glyformin Prolong imatha kuyambitsa hypoglycemia.

Imathandizira mayamwidwe a metformin nifedipine.

Mankhwala a Cationic, amenenso amasungidwa mu ngalande za impso, amachedwetsa kuyamwa kwa metformin.

Ndemanga za Glformin Prolong

Ngakhale kuti aliyense ali ndi matenda awo a shuga ndipo amatuluka mosiyanasiyana, momwe algorithm amachitidwira zinthu ndizofala, makamaka kwa mtundu wachiwiri wa matenda ashuga. About Gliformin Prolong mu shuga mellitus, ndemanga ndizosakanikirana, koma kuwunika momwe mankhwalawa amapezekera popanda kuganizira zovuta zonse zamatenda ndi moyo wawo ndizovuta.

Madokotala amayang'ana kwambiri kuti Glyformin Pronge SD imalipira, koma amafunikira thandizo. Ndani amamvetsetsa kuti zakudya ndi maphunziro akuthupi ndizosatha, zidzakhala zachilendo ndi Glformin. Kulemera kuyenera kuyendetsedwa ndi njira iliyonse, izi ndizofunikira kwambiri. Ndi chakudya chamagulu, zoletsa ndizosavuta kunyamula ndipo zotsatira zake zimakhala zachangu.

Ngati mulibe chilimbikitso chokwanira, lingalirani za phazi lolumidwa, mavuto ammaso komanso vuto la impso, osanenapo vuto la mtima kapena kugunda kwam'mimba, komwe kumachitika nthawi iliyonse komanso zaka zilizonse. Ndipo awa sangokhala upangiri wa nyuzipepala ya banja Lamlungu - awa ndi malamulo achitetezo, omwe, monga mukudziwa, olembedwa m'magazi.

Zotsatira za pharmacological

Gawo la Glyformin Prolong metformin ndi biguanide yokhala ndi hypoglycemic effect, yomwe imachepetsa magulu a glucose a basal ndi postprandial plasma. Simalimbikitsa insulin katemera chifukwa chake sayambitsa hypoglycemia. Zimawonjezera chidwi cha zotumphukira zolandilira ku insulin ndikugwiritsa ntchito shuga ndi maselo. Imachepetsa kupanga shuga kwa chiwindi poletsa gluconeogeneis ndi glycogenolysis. Kuchepetsa mayamwidwe m'matumbo.

Metformin imathandizira kapangidwe ka glycogen pochita glycogen synthase. Kuchulukitsa kuthekera kwamitundu yonse yamtundu wama glucose oyenda.

Ngakhale mutatenga Metformin, thupi la wodwalayo limakhalabe lolimba kapena limatsika pang'ono.

Metformin imakhala ndi phindu pa kagayidwe ka lipid: imachepetsa kuchuluka kwa cholesterol yathunthu, lipoproteins yotsika komanso triglycerides.

Mwachidule

Gliformin ndi mankhwala omwe amathandizira kuchepetsa shuga ya magazi. Nthawi yomweyo, kuteteza insulini sikokwanira. Poyerekeza ndi analogues, mankhwalawa amakhala ndi malingaliro abwino komanso mtengo wotsika mtengo. Saloledwa kuigwiritsa ntchito popanda kufunsa katswiri.

Gliformin ndi mankhwala a hypoglycemic ogwiritsira ntchito pakamwa, ndi a gulu la Biguanides. Mankhwala amalepheretsa glycogeneis mu chiwindi, amachepetsa mayamwidwe, amachititsa chidwi cha minyewa kupita ku insulin ya mahomoni, komanso amathandizira kugwiritsa ntchito shuga.

Nthawi yomweyo, mankhwalawa sangathe kukopa kupanga insulin, amachepetsa kuchuluka kwa ma triglycerides, lipoproteins yotsika kwambiri, komanso amathandizira kudziwa zolemetsa. Kuphatikiza apo, chifukwa cha kuletsa kwa plasminogen inhibitor ndi mtundu wa minofu, mphamvu ya fibrinolytic imachitika.

Pa phukusi limodzi la mankhwalawo mu zokutira filimu, wodwalayo ayenera kupereka ma ruble 300, mapiritsi a Glformin omwe ali ndi gawo logawa amagula pafupifupi ma ruble 150. Ndemanga za mankhwalawa ndizabwino, nthawi zambiri zimapangitsa kuti thupi lizisintha.

Malangizo ogwiritsira ntchito mapiritsi

Zisonyezero zogwiritsira ntchito mankhwalawa ndi mtundu wachiwiri wa matenda osokoneza bongo a shuga, pamene kudya mosamalitsa ndi mankhwala a gulu la sulfonylurea alibe phindu. Glyformin imalembedwanso mtundu wa shuga 1 ngati adjunct wa jakisoni wa insulin.

Panthawi yamankhwala, kugwira ntchito kwa impso kuyenera kuyang'aniridwa, pafupifupi miyezi isanu ndi umodzi ndikulimbikitsidwa kuti mupange kusanthula kuti muwone mkaka wa m'magazi.

Mapiritsi amatha kuledzera pakudya kapena mutatha kudya, mlingo woyenera uyenera kutumikiridwa ndi dokotala, poganizira zotsatira za kuyesedwa kwa magazi:

• kumayambiriro kwa mankhwala, mankhwalawa si oposa gramu imodzi patsiku,
• pambuyo masiku 15, kuchuluka kwa ndalama kumachulukitsidwa.

Mulingo woyenera wokonza sayenera kupitilira magalamu awiri patsiku, uyenera kugawidwa moyenera pazigawo zingapo. Anthu odwala matenda ashuga okalamba tsiku lililonse amalimbikitsidwa kuti amwe mankhwala ambiri a gramu imodzi.

Ngati dokotala amupatsa mankhwala a Glformin a matenda ashuga, wodwalayo ayenera kudziwa kuti mapiritsi amatha kuyambitsa zovuta zina mthupi. Kumbali ya endocrine dongosolo, hypoglycemia imayamba, mbali ya magazi, magazi amadzimadzi amatha, pamtundu wa metabolism akusowa. Thupi nthawi zina limagwiritsa ntchito mankhwala osokoneza bongo:

Kuchokera ku ziwalo zam'mimba zam'mimba kumakhala kuphwanya kudya, kutsegula m'mimba, kusanza, kukoma kwazitsulo mkamwa.

Ngati pakachitika zovuta zina, akuwonetsa kukana chithandizo ndi Gliformin, kukaonana ndi dokotala.

Mankhwala Glyformin (malangizo ake amapezeka momasuka pa intaneti) angagwiritsidwe ntchito moyenera kulephera kwa impso, koma pokhapokha pakuwoneka kuti pakuwonjezereka kwa lactic acidosis. Pankhaniyi, ntchito ya impso imayang'aniridwa nthawi zonse (kamodzi pa miyezi 3-6), pomwe mawonekedwe a creatinine amatsika mpaka kufika pa 45 ml / min, chithandizo chimayimitsidwa nthawi yomweyo.

Ngati ntchito ya impso yafupika mwa odwala matenda ashuga apamwamba, mulingo wa metformin uyenera kusintha.

Contraindication, kuyanjana kwa mankhwala

Gliformin sayenera kutumikiridwa chifukwa cha ketoacidosis, matenda osatha a chiwindi, matenda a shuga, mtima, kulephera kwa m'mapapo, panthawi yapakati, yoyamwitsa, kupatsirana kwa myocardial, kuzindikira kwambiri magawo a mankhwala.

Tengani mosamalitsa mankhwala othandizira matenda a etiology, musanachite opareshoni yayikulu.

Mphamvu ya mankhwala ingathe kuchepa limodzi ndi mankhwala:

• glucocorticosteroid mankhwala
• mahomoni a chithokomiro
• okodzetsa
• nicotinic acid
• mukamamwa mankhwala oletsa kubereka.

Ngati metformin imagwiritsidwa ntchito limodzi ndi insulin, zotumphukira za sulfonylurea, mankhwala osapweteka a antiidal, ndi beta-blockers, pali mwayi wowonjezeranso zotsatira zake.

Kutalika kwa Glformin

Nthawi zina, wodwala wodwala matenda a shuga amawonetsedwa kwa nthawi yayitali - Glformin. Amatengedwa pakamwa ndi madzi okwanira. Chidachi chitha kuthandizira paokha kapena kukhala gawo la mankhwala ophatikiza.

Ngati munthu wodwala matenda ashuga sanalandire metformin, amalimbikitsidwa pa 750 mg kamodzi patsiku. Pambuyo pa masabata awiri, dokotala amasintha mlingo (imwani mapiritsi 2 a 750 mg), kutengera zotsatira za kuyesedwa kwa shuga. Ndi kuchuluka pang'onopang'ono mu kuchuluka kwa mankhwalawa, kumachepa zovuta zomwe zimapangitsa kuchokera kugaya chakudya, makamaka, matenda osokoneza bongo amatha.

Ngati mlingo woyenera saloledwa kukwaniritsa kuchuluka kwa chiwopsezo cha glycemia, ndikofunikira kutenga mlingo waukulu wa mankhwalawa - mapiritsi atatu a 750 mg Prolong kamodzi patsiku.

Anthu omwe amadwala matenda ashuga omwe amatenga metformin ngati mankhwala amamasulidwa nthawi zonse:

1. kumwa Zakudya zofanana
2. ngati atha kupitirira 2000 mg, kusintha kwa mankhwala kwa nthawi yayitali sikumadziwika.

Kuti mukwaniritse kuyang'anira kwambiri glycemic, metformin ndi insulin ya mahomoni imagwiritsidwa ntchito ngati mankhwala osakaniza. Choyamba, imwani mankhwalawa muyezo wa mankhwalawa (piritsi limodzi 750 mg) pakudya, ndipo kuchuluka kwa insulin kuyenera kusankhidwa payekha, kutengera shuga la magazi.

Kuchuluka kwa tsiku, ndizovomerezeka kumwa osaposa 2250 mg ya mankhwala, kuwunika kwa madokotala kumawonetsa kuti, ngati mkhalidwe wa thupi umayendetsedwa moyenera, ndikotheka kusintha kwa kumwa mankhwalawa ndikutulutsidwa kwa metformin muyezo wa 3000 mg.

Zimachitika kuti wodwalayo adaphonya kumwa mankhwalawo, pomwe amamuwonetsa kumwa piritsi lotsatira nthawi yokhazikika. Simungatenge mlingo wawiri wa metformin, izi zimapangitsa kukula kwa zosasangalatsa zammbali, kukulitsa zizindikiro za matenda ashuga, zomwe siziyenera kuloledwa.

Kukula kwa Glyformin kuyenera kutengedwa tsiku lililonse, kupewa yopuma.

Wodwalayo ayenera kudziwitsa adokotala za kutha kwa chithandizo, kudziwa malingaliro ake.

Analogs, ndemanga za madokotala

Chifukwa cha kupezeka kwa ma contraindication, mankhwalawa sioyenera odwala ambiri, chifukwa ngati pakufunika kusankha ma analogues a mankhwalawo, amakhalanso ndi zinthu zingapo zogwira ntchito (250, 500, 850, 1000). Glformin akhoza kukhala pamtundu wina ndi mankhwala:

Anthu odwala matenda ashuga omwe amamwa kale mankhwala a Glformin akuwonetsa kuti ali ndi vuto lochulukirapo. Nthawi zambiri, izi zimachitika chifukwa chogwiritsa ntchito molakwika mankhwalawa.

Mankhwala osokoneza bongo amatha kuyambitsa matenda a lactic acidosis. Mawonetsedwe ake akuluakulu: kupweteka kwa minofu, kusanza, nseru, kusokonezeka kwa chikumbumtima. Zizindikiro zotere zikawoneka, ndikofunikira kuti musamwe mankhwalawo.

Madotolo akuti mankhwala a Glformin amatha kuthana ndi matenda a shuga moyenera, malinga ngati mankhwalawo amawonetsedwa mosamala. Kuphatikizanso kwina kwa mankhwalawo ndi mtengo wovomerezeka komanso kupezeka kwa mafakisi.

Endocrinologists amachenjeza kuti munthawi yonse ya mankhwala, mayeso mwadongosolo a serum creatinine amafunikira. Glyformin wa mankhwala osokoneza bongo sayenera kumwedwa:

1. ndi zakumwa zoledzeretsa,
2. mankhwala omwe amakhala ndi ethanol.

Tsoka ilo, matenda ashuga asanduka matenda wamba, komanso pakati pa achinyamata. Mankhwala, ndikofunikira kupereka mankhwala omwe amathandizira kuchepetsa matenda a glycemia, umodzi mwa mankhwalawa anali Glformin. Ngati malangizo ogwiritsira ntchito akatsatidwa ndendende, momwe mankhwalawo amathandizira pakapita kanthawi kochepa.

Zambiri zokhudzana ndi kuchepetsa shuga zimaperekedwa mu kanema munkhaniyi.

Mlingo ndi makonzedwe

Gliformin ayenera kumwedwa nthawi yakudya kapena musanadye, osafuna kutafuna ndi kumwa ndi kuchuluka kwamadzimadzi.

Mlingo wa mankhwalawa uyenera kukhazikitsidwa ndi dokotala payekhapayekha, kutengera kuchuluka kwa shuga m'magazi.

Mlingo woyambirira nthawi zambiri umakhala 500-1000 mg patsiku kapena 850 mg kamodzi patsiku. Pambuyo pa masiku 10 mpaka 14, mlingo umatha kuwonjezeka pang'onopang'ono kutengera mtundu wa glycemia.

Mlingo wokonza ndi 1500-2000 mg patsiku. Mlingo wapamwamba tsiku lililonse ndi 3000 mg. Kuti muchepetse zovuta mmatumbo, tikulimbikitsidwa kugawa Mlingo wa tsiku ndi tsiku mu 2 kapena 3 waukulu.

Kwa odwala okalamba, Mlingo wa tsiku ndi tsiku wa Glformin sayenera kupitirira 1000 mg.

Chifukwa chowonjezera chiopsezo cha lactic acidosis milandu yovuta kwambiri ya metabolic, mlingo uyenera kuchepetsedwa.

Zotsatira zoyipa

Kugwiritsa ntchito Gliformin kumatha kuyambitsa zotsatirazi pazakudya zamagetsi:

• Kusanza ndi kusanza
• Kupanda chilimbikitso
• Kupweteka kwam'mimba
• Kutsegula m'mimba
• Kulawa kwazitsulo mkamwa
• Zachisangalalo.

Monga lamulo, Zizindikiro zofananira zimawonedwa kumayambiriro kwa chithandizo chamankhwala ndikupereka okha.

Nthawi zina, gliformin yochokera ku hematopoietic system imatha kupangitsa kuti magazi anga akhale am'madzi.

Mukamagwiritsa ntchito mankhwala osokoneza bongo a endocrine, mankhwalawa amatha monga hypoglycemia.

Pa gawo la kagayidwe kachakudya kawirikawiri, kupanga lactic acidosis ndikotheka, komwe kumafunika kuthetsedwa kwa mankhwalawa.

Glformin ingayambitsenso matupi awo sagwirizana pakhungu.

Ngati zotheka zikuchitika, sinthani mlingo wa mankhwalawo kapena onetsani.

Malangizo apadera

Pa mankhwala ndi Glformin, ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi, ntchito yaimpso ndi plasma lactate wambiri.

Pa mankhwala, kugwiritsa ntchito zakumwa zoledzeretsa, komanso mankhwala omwe amakhala ndi ethanol, ndizoletsedwa.

Masiku ano, Gliformin alibe maganizidwe. Kuyenderana kwa mankhwalawa ndi awa:

• Bagomet,
• Diaformin OD,
• Forin Pliva,
• Metformin
• Metformin Canon
• Metformin Zentiva,
• Metformin teva
• Metformin MV-Teva,
• Metformin Zentiva,
• Metformin Richter,
• Glucophage Long,
• Kuchulukitsa,
• Novoformin.

Migwirizano ndi magwiritsidwe akusungidwa

Malinga ndi malangizowo, Gliformin iyenera kusungidwa m'malo owuma otetezedwa ndi dzuwa, kuti asawone ana. Kutentha kosungira sikuyenera kupitirira 25 ° C.

Moyo wa alumali wa mapiritsi okhala ndi mafilimu ndi zaka 2, ndipo mapiritsi a 500 mg ndi zaka zitatu.

Kodi mwapeza cholakwika m'mawuwo? Sankhani ndikusindikiza Ctrl + Lowani.