Diabeteson MV: Malangizo ntchito, ndemanga, mitengo yotsika mtengo

Diabeteson MV ndi mankhwala ogwiritsidwa ntchito kwambiri pochiza matenda a shuga a mtundu wachiwiri. Amawonetsedwa makamaka kwa odwala matenda ashuga popanda kulemera kwambiri ndipo amatchula kukana kwa minofu ku insulin, popeza mapiritsi amathandizira kukula pang'ono pang'onopang'ono ndikuthandizira kapamba.

Wodziwika dzina la mankhwalawa ndi gliclazide. "Diabeteson MV" ndi dzina lamalonda la kampani yopanga mankhwala yaku France, dzina lake Servier, amawapatsanso mapiritsi awa mumapangidwe amomwe amapangira mankhwala, chifukwa ndi okwera mtengo kwambiri kuposa ma generics (Diabinax, Glidiab, Diabefarma) omwe amapangidwa motengera gliclazide.

Chidule cha MV chimatanthawuza kuti Diabetes yemwe ali ndi masinthidwe osinthidwa ndipo gawo lokhazikika silikuwoneka lokha, koma masana, magawo ofanana.

Ubwino wa Diabeteson MV

Ngati tingayerekeze mankhwalawa ndi mitundu yosiyanasiyana ya mndandanda wa sulfonylurea, ndiye kuti pakalibe kutchulidwa, mkwiyo wake udzakhala wapamwamba.

1. Diabeteson MV imabwezeretsa glycemic bwino,
2. Glyclazide imalimbikitsa gawo lachiwiri la kutulutsidwa kwa mahomoni, nthawi yomweyo kufikira pazofunikira zamagulu a chakudya.
3. Mankhwala amachepetsa chiopsezo cha thrombosis,

Pamodzi ndi mndandanda wotsimikizika wa zabwino, mankhwalawa amakhalanso ndi zovuta.

• Maselo B omwe amachititsa kuti insulini ipangidwe amatha.
• Kwa zaka 2-8 (kutengera kulemera kwa thupi, kuthamanga kwa anthu owonda), odwala matenda ashuga omwe ali ndi mtundu wachiwiri wa matenda amapezeka ndi mtundu woyamba wa matenda ashuga.
• Mankhwalawa samachotsa kufooka kwa minofu, koma mpaka kumakulitsa.
• Kuwongolera mbiri ya glycemic sikuti kumatsimikizira kuti chiwerengero cha anthu omwalira chifukwa cha matenda ashuga chikusintha (malinga ndi kafukufuku yemwe adadziwika ndi likulu ladziko lonse la ADVANCE).

Pofuna kuti musakakamize thupi kusankha pakati pamavuto amkaka ndi mtima, mapiritsi ayenera kuthandizidwa pakuwongolera zakudya ndi minofu yanu.

Kusintha kwa moyo kumathandizanso kuchepetsa chiwopsezo cha mtima mu mawonekedwe a glycemia wambiri, kutsika kwa kuthamanga kwa magazi, kunenepa kwambiri, komanso kusokonezeka kwa lipid metabolism.

Kufotokozera kwa mawonekedwe ndi mawonekedwe

Gawo lalikulu la fomula ndi gliclazide - mankhwala omwe ali ndi mphamvu ya hypoglycemic, woimira gulu la mankhwala a sulfonylurea. Kuphatikizika kwa mankhwalawa kumathandizidwa ndi mphamvu yayitali ya lactose monohydrate, maltodextrin, hypromellose, magnesium stearate, silicon dioxide.

Mapiritsiwo amatha kuzindikiridwa ndi mawonekedwe owondera ndi mzere wogawanika komanso chidule "DIA 60" mbali iliyonse.

Mankhwalawa amadzaza matuza kwa zidutswa 15-30, m'bokosi lamakatoni limodzi ndi malangizo omwe angathe kukhala ndi ma plates ngati amenewa.

Mankhwala omwe mumalandira amamasulidwa. Kwa Diabeteson MV, mtengo wake siwowonongera ndalama zambiri, chifukwa mapiritsi 30 pafupifupi ma ruble 300 ayenera kulipira. Mankhwalawa sanaphatikizidwe pamndandanda wamankhwala okondweretsa antidiabetes. Tsiku lotha ntchito lomwe linapangidwa ndi wopanga siliposa zaka ziwiri. Mankhwalawa safuna mikhalidwe yapadera kuti asungidwe.

Mankhwala

Mankhwala a Sulfonylurea, omwe akuphatikizapo Diabeteson MV, amathandizira ntchito ya kapamba ndi maselo ake a b, omwe amayang'anira kupanga insulin. Mlingo wowonekera kwa mankhwalawa ndiwachifundo, mwachitsanzo, Maninil wachipembedzo amakhala wankhanza kwambiri.

Mankhwalawa atha kukhala othandiza ndi zizindikiro zotchulidwa zakutha kwa kapamba, pomwe popanda kukondoweza sakupatsanso insulini yofunikira kulipira glycemia. Ndi mtundu uliwonse wa kunenepa kwambiri, mankhwalawa sawonjezedwanso.

Diabeteson MV imabwezeretsa gawo loyamba la insulin kaphatikizidwe ngati kuchepa kwake kumachitika m'thupi. Mu matenda a shuga ndi mtundu wachiwiri, mankhwalawa amathandizira kuti inshuwaransi isanayambike pamene thupi limalowa m'thupi ndikuyambiranso gawo lachiwiri la kuzungulira.

Kuphatikiza pa kutsika kotsimikizika kwa ma glycemic indices, kumwa mankhwala kumakhudza thanzi la mitsempha yamagazi komanso dongosolo la magazi. Kuchepetsa kuphatikiza kwa maselo am'magazi (kuphatikiza), kumachepetsa chiopsezo cha mtima wam'mimba, kuwalimbikitsa kuchokera mkati, kupereka chitetezo cha angioprotective.

Mankhwala osokoneza bongo a algorithm ndi mndandanda wotsatira.

1. Nthanga imayamba kusonkhezeredwa kuti itulutse timadzi m'magazi,
2. Ndiye gawo loyambirira la insulin lotsekera limayesedwa ndikubwezeretsedwa,
3. Kuchepetsa mapangidwe am magazi m'matumbo ang'onoang'ono, kuphatikiza kwa maselo ambiri kumachepetsedwa,
4. Mofananamo, pali antioxidant ena.

Kugwiritsa ntchito kamodzi kamodzi pamankhwala kumapereka kuchuluka kwa glibenclamide patsiku. Mulingo wokhazikika wa C-peptide ndi insulin umapangidwa m'thupi osati kale kuposa zaka 2 zamankhwala okhazikika.

Pharmacokinetics

Mankhwalawa amalowetsedwa m'matumbo athunthu. M'magazi, zomwe zimapangika zimadziunjikira pang'onopang'ono kwa nthawi ya maola 6. Mlingo womwe umakwaniritsidwa umatha maola 6 mpaka 12. Kusinthika kwa magulu osiyanasiyana a matenda ashuga kumakhala kochepa.

Munthawi yomweyo ndi mankhwala, kudya michere m'thupi sikumasintha ma pharmacokinetic mawonekedwe a gliclazide. Kulumikizana ndi mapuloteni am magazi kumasungidwa pa 95%, Vd - mpaka 30 malita.

Gliclazide metabolism imachitika m'chiwindi, palibe metabolites yogwira m'magazi.

Impso zawo zimachotsedwa (mpaka 1% mwanjira yomweyo). T1 / 2 ya gliclazide imasiyanasiyana pamtunda wa maola 12-20.

Mlingo ukachulukitsa kufika pa mulingo wokwanira (120 mg), dera lomwe lili pamzere womwe umadziwika ndi nthawi komanso kugawa kumawonjezeka molunjika.

Zizindikiro zogwiritsidwa ntchito

Kusintha kwakanema kwa mankhwala omwe amakhala ndi mphamvu yayitali kunapangidwa kuti ibwezeretse mbiri ya glycemic komanso kupewa zovuta za matenda ashuga (stroke, retinopathy, kugunda kwa mtima, nephropathy, gangrene yam'mphepete).

Amalembedwa kwa odwala matenda ashuga omwe ali ndi vuto lozolimbitsa thupi lokhala ndi mtundu wa 2 shuga wambiri komanso wowonda mawonekedwe osakhala ndi minyewa yolimbana ndi insulin.

Amagwiritsidwanso ntchito ndi osewera kuti azitha kukhudzika kwa minofu kuti apange insulin, yomwe imathandizira kupindula kwa minofu.

Monga mankhwala oyambira a odwala matenda ashuga, Diabeteson MV siyabwino. Ndiwowopsa kupaka mankhwalawa chifukwa cha kunenepa kwambiri, chifukwa kapamba, ndipo motero amagwira ntchito mopitirira, amapanga mitundu iwiri ya insulin yomwe singalepheretse shuga. Diabeteson MV pankhaniyi imatha kupatsanso imfa (kuchokera ku zovuta zamtima).

Kuti muphunzire ubale pakati pa kusankha kwa mankhwala oyamba a matenda oyamba a shuga 2 ndi chiopsezo cha kufa, maphunziro apadera adachitika. Mapeto ake ndiwodziwikiratu.

1. Mu odwala matenda ashuga omwe amalandila mankhwala a sulfonylurea, poyerekeza ndi odzipereka omwe amatenga metformin, kuthekera kwa kufa ndi matenda amtima kunali kawiri konse, matenda a mtima (CHD) anali 4,6 kukwera, ndipo magazi amitsempha yamagazi Katatu.
2. Mwayi woti amwalira ndi NMC komanso matenda amtima wamphamvu anali ambiri mwa anthu odwala matenda ashuga omwe amamwa mankhwala osokoneza bongo a glibenclamide, glycvidone, glyclazide kuposa omwe amathandizidwa ndi metformin.
3. Poyerekeza ndi gulu lomwe limathandizidwa ndi glibenclamide, otenga nawo mbali omwe adalandira gliclazide adawonetsa zotsatirazi: kutsika kwa 20% pakufa kwathunthu, ndikuchepetsa 40% yakufa kwa UC ndi CCC.

Chifukwa chake, kusankha kwa Diabeteson MV ngati mankhwala a mzere woyamba, monga mankhwala ena aliwonse a sulfonylurea, kumawonjezera mwayi wakufa zaka 5 kawiri, kulandira infaration ya myocardial - katatu, kukomoka kwa ubongo - katatu. Ndi matenda omwe adapezeka kumene, Metformin ngati chithandizo chamtundu woyamba ndi njira yabwino kwambiri.

Mwachilungamo, ziyenera kudziwika kuti chifukwa chokhala ndi matenda osokoneza bongo a Diabeteson MV, chiopsezo chotenga matenda a atherosulinosis chachepa kwambiri. Oimira ena kalasi la mankhwalawa sanawonetse zofanana. Kuthana ndi kuthekera kwa Diabeteson MV kungafotokozedwe ndi kupezeka kwake mu antioxidants omwe amateteza minofu ku makutidwe ndi okosijeni.

Ubwino ndi kupweteka kwa odwala matenda ashuga - mu kanema:

Contraindication

Diabeteson MV ndi m'badwo watsopano wamankhwala wokhala ndi mphamvu yambiri. Amasiyana ndi mawonekedwe onse a kalasi la sulfonylurea malinga ndi kukula kwa zovuta komanso kuchuluka kochepa kwa zovuta.

Koma, monga mankhwala aliwonse opangidwa, gliclazide imakhala ndi zotsutsana zingapo:

• Kuzindikira kwakukulu pazomwe zimapangidwira mankhwalawo ndi mankhwala a sulfonylurea,
• Mtundu woyamba wa shuga
• Zomwe zimachitika ndi matenda ashuga a ketoacidosis, chikomokere, komanso matenda ake;
• Zambiri matenda a impso ndi chiwindi, kusintha kwa insulin,
• Mimba komanso kuyamwa
• Chithandizo cha munthawi yomweyo ndi miconazole,
• Zaka mpaka 18.

Mankhwalawa ali ndi lactose, chifukwa chake samawonetsedwa chifukwa cha tsankho lake, chifukwa cha glucose-galactose malabsorption, galactosemia. Sitikulimbikitsidwa kuphatikiza danazol ndi phenylbutazone ndi Diabeteson MV.

Mimba

Palibe chidziwitso chakuthandiza azimayi oyembekezera omwe ali ndi gliclazide, komanso deta yothandizira mankhwalawa odwala matenda ashuga omwe ali ndi mankhwala a sulfonylurea ambiri.

Poyeserera nyama zazikazi, mphamvu ya teratogenic ya gliclazide sinawonetsedwe.

Kuti muchepetse chiwopsezo cha matenda obadwa nawo, kuwunikira nthawi zonse komanso chithandizo choyenera cha matenda a shuga a 2 ndikufunika. Mankhwala a Oral hypoglycemic sagwiritsidwa ntchito panthawiyi, amayi apakati amasamutsidwira ku insulin ndipo ndi bwino kuchita izi ngakhale pa nthawi yomwe akukonzekera kubereka.

Palibe chidziwitso chokhudza kulowa kwa gliclazide mkaka wa m'mawere, chiopsezo cha neonatal hypoglycemia sichinakhazikitsidwe, chifukwa chake, pakumwa ndi Diabeteson MV, kuyamwitsa kumatsutsana.
Palibe umboni uliwonse wogwira ntchito komanso chitetezo cha ntchito ya Diabeteson MV ya ana, chifukwa chake, odwala matenda ashuga osaposa zaka 18, mankhwalawa samatumidwanso.

Zotsatira zoyipa

Diabeteson MV ili ndi chidziwitso chogwiritsa ntchito ndi zotsutsana zochepa komanso zoyipa, zomwe zimayesedwa ngati hypoglycemia, pomwe kuwerenga kwa glucometer kumagwera pansi pazomwe mukufuna.

Mutha kusiyanitsa dziko loopsa ndi:

1. Mutu ndi chizungulire,
2. Chikhumbo cha Wolf
3. Matenda a Dyspeptic,
4. Kutaya mphamvu, kufooka,
5. Thukuta kwambiri
6. Vuto la mtima
7. Mkhalidwe wamanjenje, wokondwa, wopsinjika,
8. Adrenergic zimachitika, kugwedeza,
9. Mavuto olankhula, delirium,
10. Zowonongeka
11. Misempha spasms
12. Kusathandiza, kulephera kudziletsa,
13. Kukomoka, chikomokere.

Ndi mtundu wofatsa wa hypoglycemia, wozunzidwayo amapatsidwa shuga, ndi mawonekedwe akulu, kuchipatala chofunikira ndikofunikira. Mkhalidwe wa hypoglycemia ndi wowopsa ndikuyambiranso, chifukwa chake ndikofunikira kuyendetsa bwino pambuyo pakupuma kwa matenda.

Mwa njira, poyerekeza ndi ochiritsira Diabeteson, mawonekedwe ake (ndi kumasulidwa pang'onopang'ono) amakupatsani mwayi wogawa katunduyo mthupi mofanananira. Izi zimachepetsa kwambiri chiopsezo cha hypoglycemia.

Kuphatikiza pa hypoglycemia, palinso zovuta zina zomwe sizinachitike.

• Urticaria, zotupa zoyipa, edema ya Quincke,
• Matenda Ammimba,
• Matenda owenderera m'magazi a kuchepa kwa magazi, kuchepa kwa maselo oyera a magazi,
• Mavuto apakanthawi owonekera chifukwa cha kusintha kwa glycemia, nthawi zambiri pakusintha kwa mankhwalawa.
• Kuchulukitsa kwa chiwindi michere AST ndi ALT, nthawi zina, chiwindi.

Ngati Diabeteson MV adayikidwa m'malo mwa mankhwala ena a hypoglycemic, ndikofunikira kuwunika magawo a glycemic kwa masabata awiri kuti aletse kukhazikika kwa zotsatira za mankhwala awiri owopsa a hypoglycemia.

Panthawi ya mayeso azachipatala a mbiri yabwino ya ADVANCE, kusiyana kochepa (kochokera pakuwona kachipatala) kusiyana pakati pa owongolera ndi magulu oyesera kunawululidwa. Pafupipafupi komanso kuopsa kwa hypoglycemia kumakhala kotsika. Milandu yambiri ya hypoglycemia imadziwika motsutsana ndi maziko a zovuta mankhwala molumikizana ndi kukonzekera kwa insulin.

Zotsatira Zogwiritsa Ntchito Mankhwala

Imawonjezera ntchito ya Diabeteson MV miconazole (onse mawonekedwe a jakisoni ndikugwiritsa ntchito kunja). Kuphatikizikaku kumatsutsana kwenikweni, chifukwa kumatha kupangitsa hypoglycemia.

Sitikulimbikitsidwa kuphatikiza gliclazide ndi phenylbutazone. Ndi kayendetsedwe ka kayendetsedwe, kayendedwe ka hypoglycemic komwe kamachokera ku sulfonylurea kumalimbikitsidwa: kusiya mankhwala kumachepetsa, phenylbutazone imachotsa mu protein ya protein. Ngati palibe mankhwalawa omwe asinthidwe, ndikofunikira kusintha muyezo wa gliclazide ndikuwunika glycemia mosamala nthawi yonse yamankhwala ndikatha maphunzirowa.

Kuchulukitsa chiopsezo cha glycemia ethanol ndi mankhwala ozikirapo. Kwa nthawi yamankhwala omwe ndimalandira ndi Diabeteson MV, ndikofunikira kusiya zakumwa zoledzeretsa ndi mankhwala omwe amamwa mowa.

Kuphatikiza ndi mankhwala a antidiabetesic amalembedwa mosamala: insulin, biguanides, acarbose, diazolidinediones, GLP-1 antagonists, DPP-4 inhibitors, β-blockers, MAO ndi ACE inhibitors, fluconazole, sulfonamide mankhwala, NP. Kuphatikiza kulikonse kotereku kumawonjezera kuchuluka kwa matenda a Diabeteson MV ndipo kumafunikira kuchepa kwa mlingo ndikuwonetsetsa mbiri ya glycemic.

Imafooketsa mphamvu ya Diabeteson MV Danazole, yomwe imawonjezera kuchuluka kwa shuga mu plasma. Pogwiritsa ntchito momwemonso, kuwunika kwa mankhwalawa komanso kuwunika kwa glycemic ndikofunikira pazomwe zimachitika pakanamaliza. Zofananazo zimawonedwa ndi jakisoni a iv a adrenergic agonists.

Glyclazide + chlorpromazine maofesi amapatsidwa mosamala. Mlingo wambiri, antipsychotic amachepetsa kupanga insulin, amathandizira kuchuluka kwa shuga m'magazi. Ndikofunikira kuwerengetsa kuchuluka kwa mankhwala mosamala.

GCS ndi tetracosactide ndi njira ina iliyonse yogwiritsira ntchito (mafupa, khungu, njira ya rectal) kumawonjezera shuga m'magazi, kumayambitsa kupezeka kwa ketoacidosis, komwe kumachepetsa kulolerana kwa zinthu zopatsa mphamvu. Pazigawo zoyambirira za mankhwalawa, kumwa mankhwala pang'ono pang'onopang'ono ndikuwunika magawo a glucometer ndikofunikira nthawi yonse yogwiritsidwa ntchito molumikizana komanso mukamaliza.

Njira yogwiritsira ntchito

Kwa Diabeteson MV, malangizo ogwiritsira ntchito amalimbikitsa kuti odwala matenda ashuga amwe mankhwalawa m'mawa, pamodzi ndi kadzutsa. Monga mankhwala opatsirana odwala matenda ashuga, endocrinologist imasankha yekha mankhwalawo, poganizira zotsatira za kusanthula, gawo la matenda ashuga, matenda oyanjana, momwe thupi limathandizira pakumwa mankhwalawo.

Mlingo uliwonse (kuyambira 30 mpaka 120 mg, womwe ndi mapiritsi a 0.5-2), kumwa gliclazide ndi imodzi. Ngati dongosolo lawonongedwa, kuwirikiza mulingo wowopsa - thupi limafunikira nthawi yokwanira, popanda zotsatira zosafunikira, chizolowezi.

Mu mtundu wanthawi zonse, mulingo woyambira ndi Ѕ tebulo. (30 mg). Kwa odwala matenda ashuga okalamba, kumwa mankhwala sikofunikira.

Ngati chizolowezi chotere chimapereka chiwongolero chonse cha glycemia, chitha kugwiritsidwa ntchito ngati kukonza mankhwala. Ndi osakwanira kuwongolera, mlingo umasinthidwa, kubweretsa chizolowezi cha tsiku ndi tsiku ku 60.90 komanso ngakhale 120 mg. Mlingo wothandizira umachitika pambuyo pa masiku 30 - zimatenga nthawi yochulukirapo kuti muwone momwe ntchito yomwe mwasankhayo idagwirira ntchito.

Ngati wodwalayo alibe kusintha m'masabata awiri kuti akhale bwino, kupatsanso gawo limodzi pakatha theka la mwezi. Mulingo wovomerezeka wachifundo wa gliclazide ndi 120 mg.

Ngati matenda a shuga asamutsidwa kuchokera ku matenda a shuga a shuga ndikumatulutsa mwachangu gliclazide kupita ku analogue wautali, ndiye kuti piritsi la Diabeteson la 80 mg lingalowe m'malo mwanjira yofananira ndi kuchuluka kwa 60 mg kapena 30 mg.

Mukasinthira njira yina ya glycemic ndi Diabeteson MV, njira yapitayi yoyambira komanso nthawi yothetsera mankhwalawa imaganiziridwa.Nthawi zambiri pamakhala chifukwa chosinthira gawo. Mlingo woyambira umatsimikiziridwa pa 30 mg ndikuwongolera pang'onopang'ono ngati zotsatira za chithandizo sizachilendo.

Ngati T1 / 2 ya mankhwala am'mbuyomu ndi yayitali, pofuna kupewa kuyikika pazomwe zimayambitsa hypoglycemia, yopuma iyenera kutengedwa pakati pa maphunziro. Kuyambika kwa matenda a shuga a Mabetes kumapangidwanso osachepera - 30 mg ndi mwayi woperekanso gawo lina.

Diabeteson MV ikhoza kugwiritsidwa ntchito pazithandizo zovuta. Kupititsa patsogolo hypoglycemic kugwiritsa ntchito insulin, biguanides, b-glucosidase inhibitors. Zotsatira zosakhutira, mlingo wa insulin umafotokozedwa.

Malangizo owonjezera

Anthu odwala matenda ashuga omwe ali ndi impso modabwitsa komanso modekha samalimbikitsidwa kumwa mankhwala, ndikofunikira kuyang'anitsitsa glycemia ndi ntchito ya impso.

Chisamaliro chofunikira chimafunikira odwala omwe ali pachiwopsezo chokhala ndi zakudya zochepa zopatsa mphamvu, osakwanitsa kuchita masewera olimbitsa thupi, endocrine pathologies (adrenal and pituitary insuffuffence, hypothyroidism, cancellation of corticosteroids pambuyo poti agwiritsidwe ntchito kwa nthawi yayitali kapena waukulu, CVD yayikulu mu mawonekedwe a atherosulinosis kapena matenda a mtima. Gulu ili la anthu odwala matenda ashuga amalembedwa osachepera a Diabeteson MV - 30 mg.

Kuti mupeze zotsatira za 100%, mlingo umatha kukhala wokwanira mpaka 120 mg / tsiku. Chofunikira chidzakhala kusintha kwa moyo - kusintha kwa zakudya zamafuta ochepa, kuchita masewera olimbitsa thupi pafupipafupi, komanso kuwongolera zakukhosi.

Ngati ndi kotheka, mutha kuthandizira dongosolo la mankhwalawa ndi Diabeteson MV metformin, insulin, thiazolidinediones. Pankhaniyi, ndikofunika kukumbukira kupezeka kwa zotsatira zoyipa m'mankhwala aliwonse komanso mogwirizana ndi zomwe akuchita. Choyamba, tikulankhula za chiopsezo cha hypoglycemia.

Kuthandiza ndi bongo

Choopsa chachikulu cha bongo ndi vuto la hypoglycemic. Ndi zizindikiro zofatsa komanso kudziletsa kokwanira, ndikofunikira kuti muchepetse mulingo wa Diabeteson MV ndi mankhwala ena othandizira, sinthani zakudya kuti muwonjezere zopatsa mphamvu. Kuyan'anira thanzi la odwala matenda ashuga ndikofunikira mpaka glycemia ikhale yokhazikika, chifukwa kuyambiranso kumachitika motere.

Ngati zizindikiro za glycemic zatchulidwa kwambiri ndipo zikuwopseza thanzi, makamaka ngati wodwalayo sakudziwa, ali ndi nkhawa, akuwomba kachipatala, kutsatira chithandizo chamankhwala mwachangu ndikofunikira, ndikutsatira kuchipatala. Mukangoyamba kumene, wodwala matenda ashuga ayenera kubayidwa kudzera m'matumbo a 50 ml.

Kusungabe bwino (pamwambapa 1 g / l) - komanso 10% dextrose solution. Kuwunikira zizindikiro zonse zofunika kumachitika kwa maola osachepera 48. Popeza gliclazide imamangiriza mapuloteni amwazi, hemodialysis pankhaniyi siyothandiza.

Ndingasinthe bwanji Diabeteson MV

DIV Diabeteson yoyambirira, yomwe imapangidwa ndi kampani yaku France ya Serviceier, ili ndi ma analogu okwera mtengo otengera gliclazide, koma zovuta za mankhwalawa zimatha kutchulidwa kwambiri, chifukwa chake posankha muyenera kuyang'ana osati mtengo, komanso malingaliro a adotolo.

Dokotala amatha kukupatsani zamagetsi:

1. RDiabefarm, Glyclazide, Glucostabil, Glidiab,
2. Czech Gliklad,
3. Yugoslavian Predian ndi Glioral,
4. Indian Diabinax, Diatiku, Reklid, Glisid.

Ngati mankhwala ozikidwa ndi gliclazide sioyenera, endocrinologist angasankhe:

• Mankhwala a sulfonylurea mndandanda wokhazikika pa glibenclamide, glycvidone, glimepiride,
• Mankhwala a gulu lina, koma ndimayendedwe omwewo, mwachitsanzo, NovoNorm wochokera ku gulu ladothi.
• Mankhwala omwe ali ndi ntchito yofanana ndi Januvia kapena Galvus (DPP-4 zoletsa).

Glidiab MV kapena Diabeteson MV: zomwe zili bwino kwa wodwala wina zitha kutsimikiziridwa ndi dokotala. Zomwe zimaperekedwa kuti zigwiritsidwe ntchito pofotokoza, osati kudzifufuza komanso kudziyang'anira nokha.

Zomwe Akuluakulu a shuga a MV Amaganizira

About Diabeteson MV, ndemanga za anthu odwala matenda ashuga ndizosagwirizana: shuga imathandiza kuwongolera, koma ndi anthu ochepa omwe adatha kupewa zotsatira zoyipa. Choopsa kwambiri ndikuti mapiritsi oterowo atatha, pafupifupi aliyense amasintha insulin - ena kale, ena pambuyo pake.

Diabeteson MV sinafotokozeredwe kwa endocrinologists ndi onse odwala matenda ashuga, koma ngakhale iwo omwe ali oyenera mankhwalawa amatha kuyamba kugwiritsa ntchito mankhwalawa. Chifukwa cha mulingo woyenera kapena osagwirizana ndi dongosolo la kayendetsedwe, kugwiritsa ntchito mankhwalawa sikugwirizana ndi zomwe zalengezedwazo.

Ndi kuwonongeka kwambiri kwa matenda ashuga, ngakhale mutakhala ndi zakudya zochepa za carb komanso zolimbitsa thupi, njira zina zochiritsira zingafunike. Pali zovuta zambiri, ngati mwapatsidwa Diabeteson MV, werengani malangizo osavuta awa kuti muwonetsetse kuti nthawi yoikidwiratu idachitika.

Zambiri pa Diabeteson MV - pa kanema:

Kugwiritsa ntchito mankhwala a shuga

Mankhwala a Diabeteson mu mapiritsi amodzi ndi kumasulidwa kosinthika (MV) amaperekedwa kwa odwala omwe ali ndi matenda a shuga a 2, omwe kudya ndi kuchita masewera olimbitsa thupi sikuyendetsa bwino matenda. The yogwira pophika mankhwala ndi gliclazide. Ndi m'gulu la sulfonylureas. Gliclazide imathandizira maselo a kancreatic pancreatic beta kuti apange ndikusunga insulin yambiri m'magazi, timadzi timene timatsitsa shuga.

Ndikulimbikitsidwa kuti odwala omwe ali ndi matenda a shuga a 2 asamayike mankhwala a Diabeteson koyambirira, koma mankhwala a Metformin - Siofor, Glucofage kapena Glformin. Mlingo wa metformin pang'onopang'ono umachulukitsidwa kuchokera 500-850 mpaka 2000-3000 mg patsiku. Ndipo pokhapokha ngati mankhwalawo amachepetsa shuga mosakwanira, zochokera ku sulfonylurea zimawonjezeredwa kwa iwo.

Madokotala ambiri amapereka Diabeteson MV m'malo mwa metformin kwa odwala awo. Komabe, izi sizolakwika, sizigwirizana ndi malingaliro ovomerezeka. Gliclazide ndi metformin zimatha kuphatikizidwa. Kugwiritsa ntchito mapiritsi amenewa nthawi zambiri kumakupatsani mwayi wodwala wokhala ndi shuga wabwino kwa zaka zingapo.

Gliclazide mapiritsi otulutsidwa otulutsidwa mosiyanasiyana kwa maola 24. Mpaka pano, machitidwe othandizira odwala matenda ashuga amalimbikitsa kuti madokotala azigwiritsa ntchito Diabeteson MV kwa odwala awo omwe ali ndi matenda a shuga a 2, m'malo mwa m'badwo wam'mbuyomu sulfonylureas. Mwachitsanzo, onani nkhani ya "Zotsatira za kafukufuku wa DYNASTY (" A Diabeteson MV: pulogalamu yowonera pakati pa odwala omwe ali ndi matenda a shuga 2 nthawi zonse azolowera kuchita ")" mu magazine "Matenda a Endocrinology" No. 5/2012, wolemba M. V. Shestakova, O K. Vikulova ndi ena.

Diabeteson MV amachepetsa kwambiri magazi. Odwala monga choncho ndiosavuta kutenga kamodzi patsiku. Imakhala yotetezeka kuposa mankhwala akale - mankhwala a sulfonylurea. Komabe, imakhala ndi vuto, chifukwa ndibwino kuti odwala matenda ashuga asamamwe. Werengani pansipa zomwe zili ndi vuto la Diabetes, lomwe limafotokoza zabwino zake zonse. Tsamba la Diabetes-Med.Com limalimbikitsa chithandizo chamankhwala amtundu wa 2 wopanda mapiritsi owononga.

• Chithandizo cha matenda a shuga a mtundu wachiwiri: njira yotsatirira - yopanda njala, mankhwala osokoneza bongo komanso jakisoni wa insulin
• Mapiritsi a Siofor ndi Glucofage - metformin
• Momwe mungaphunzirire kusangalala ndi maphunziro akuthupi

Ubwino ndi zoyipa

Chithandizo cha matenda a shuga a mtundu wachiwiri mothandizidwa ndi mankhwalawa a Diabeteson MV zimapereka zotsatira zabwino pakanthawi kochepa:

• Odwala achepetsa shuga la magazi,
• chiopsezo cha hypoglycemia sichikupitilira 7%, chomwe ndi chotsika kwambiri poyerekeza ndi zina zomwe zimachokera ku sulfonylurea,
• ndikwabwino kumwa mankhwalawo kamodzi patsiku, kotero odwala samapereka chithandizo,
• mukumwa mankhwala a gliclazide pamapiritsi otulutsa, thupi la wodwalayo limakulitsidwa pang'ono.

Diabeteson MB yakhala mtundu wotchuka wa mankhwala ashuga a 2 chifukwa ali ndi zabwino kwa madotolo ndipo ndi abwino kwa odwala. Ndiosavuta nthawi zambiri kuti ma endocrinologists akupatseni mankhwala kuposa kulimbikitsa odwala matenda ashuga kuti azitsatira zakudya komanso masewera olimbitsa thupi. Mankhwalawa amachepetsa shuga ndipo amalekeredwa bwino. Palibe oposa 1% ya odwala omwe amadandaula za zoyipa, ndipo ena onse amakhutira.

Zoyipa zamankhwala a Diabeteson MV:

1. Imathandizira kufa kwa maselo a pancreatic beta, chifukwa matendawa amasintha kukhala matenda a 1 a shuga. Nthawi zambiri zimachitika pakati pa 2 ndi 8 zaka.
2. Mwa anthu ochepa thupi komanso owonda, matenda ashuga omwe amadalira insulin amayamba makamaka - osachedwa kuposa zaka 2-3.
3. Sizichotsa zomwe zimayambitsa matenda a shuga a 2 - kuchepa kwa chidwi kwamaselo kuti insulini. Vutoli limatchedwa insulin kukana. Kutenga Diabeteson kumatha kulimbikitsa.
4. Amachepetsa shuga yamagazi, koma samachepetsa kufa. Izi zidatsimikiziridwa ndi zotsatira za kafukufuku wawukulu wapadziko lonse ndi ADVANCE.
5. Mankhwalawa amatha kuyambitsa hypoglycemia. Zowona, kuthekera kwake ndikocheperako poyerekeza ndi kutengedwa kwina kutachitika. Komabe, matenda ashuga amtundu wa 2 amatha kuyendetsedwa mosavuta popanda chiwopsezo cha hypoglycemia.

Akatswiri kuyambira zaka za m'ma 1970 amadziwa kuti kupezeka kwa matenda a shuga a 2 kumapangitsa kuti matenda ashuga a 2 akhale osavuta. Komabe, mankhwalawa akupitilizabe kutumikiridwa. Cholinga chake ndikuti amachotsa mtolo kwa madokotala. Pakanakhala kuti palibe mapiritsi ochepetsa shuga, ndiye kuti madokotala amayenera kulemba zakudya, masewera olimbitsa thupi, ndi mtundu wa insulin kwa aliyense wodwala matenda ashuga. Iyi ndi ntchito yovuta komanso yosayamika. Odwala amakhala ngati ngwazi ya Pushkin: "Palibe zovuta kundinyenga, inenso ndili wokonzeka kudzinyenga." Alola kumwa mankhwala, koma sakonda kutsatira kadyedwe, masewera olimbitsa thupi, komanso makamaka jekeseni wa insulin.

Diabeteson MV - mapiritsi owononga. Komabe, zomwe zimapezeka m'mibadwo yam'mbuyomu ndi zoyipa kwambiri. Zoyipa zomwe zalembedwa pamwambapa, zimatchulidwa kwambiri. Diabeteson MV osachepera sichikhudza kufa, pomwe mankhwala ena amawonjezera. Ngati simuli okonzeka kusintha njira zachilengedwe zochizira matenda amtundu wa 2, ndiye kuti mutenge mapiritsi osinthidwa (MV).

Zowonongeka za Diabeteson pama cell a pancreatic beta kwenikweni sizikhudzanso endocrinologists ndi odwala awo. Palibe zolemba m'magazini azachipatala zokhudzana ndi vutoli. Cholinga chake ndikuti odwala ambiri omwe ali ndi matenda amtundu wa 2 alibe nthawi yopulumuka asanayambe matenda a shuga. Machitidwe awo a mtima ndi cholumikizira chochepa kwambiri kuposa kapamba. Chifukwa chake, amafa ndi vuto la mtima kapena sitiroko. Chithandizo cha matenda a shuga a mtundu 2 pochokera pakudya kopatsa mphamvu ya calcium nthawi imodzi imapangitsa matenda ashuga, kuthamanga kwa magazi, zotsatira za kuyesedwa kwa magazi chifukwa cha cholesterol ndi zina zomwe zimayambitsa mtima.

Zotsatira zakuchipatala

Momwe mayeso akulu azachipatala a Diabeteson MV anali kuphunzira VUTO: Chitetezo cha matenda a shuga komanso matenda a VAscular -
preterax ndi Diamicron MR Kuwongoleredwa Kuwunika. Idayambitsidwa mu 2001, ndipo zotsatira zake zidasindikizidwa mu 2007-2008. Diamicron MR - pansi pa dzina ili, glyclazide pamapiritsi osintha osinthika amagulitsidwa ku mayiko olankhula Chingerezi. Izi ndizofanana ndi mankhwala a Diabeteson MV. Preterax ndi mankhwala ophatikiza matenda oopsa, zosakaniza zomwe zili indapamide ndi perindopril. M'mayiko olankhula Chirasha, amagulitsidwa pansi pa dzina la Noliprel. Phunziroli lidakhudza odwala 11,140 omwe ali ndi matenda a shuga 2 komanso matenda oopsa. Adawonedwa ndi madotolo kuzipatala 215 zamayiko 20.

Diabeteson MV imatsitsa shuga, koma siyimachepetsa kufa kwa odwala omwe ali ndi matenda ashuga a 2.

Malinga ndi zotsatira za kafukufukuyu, zidapezeka kuti mapiritsi opsinjika mwa odwala omwe ali ndi matenda a shuga 2 amachepetsa pafupipafupi zovuta zamtima ndi 14%, mavuto a impso - mwa 21%, kufa - ndi 14%. Nthawi yomweyo, Diabeteson MV imachepetsa shuga m'magazi, imachepetsa kuchuluka kwa matenda a shuga ndi 21%, koma sizimakhudza kufa. Gwero la chilankhulo cha Russia - nkhani "Kutsogolera kwa odwala omwe ali ndi matenda a shuga 2: zotsatira zakufufuza" muzolemba System Hypertension No. 3/2008, wolemba Yu. Karpov. Gwero loyambirira - "Gulu la Mgwirizano WABODZA. Kulamulira kwamphamvu kwa shuga m'magazi ndi zotumphukira zake kwa odwala omwe ali ndi matenda a shuga a 2 ”mu New England Journal of Medicine, 2008, No. 358, 2560-2572.

Odwala omwe ali ndi matenda amtundu wa 2 amamulembera mapiritsi ochepetsa shuga ndi jakisoni wa insulin ngati zakudya ndi zolimbitsa thupi sizimapereka zotsatira zabwino. M'malo mwake, odwala safuna kutsatira zakudya zochepa zopatsa mphamvu. Amakonda kumwa mankhwala. Amakhala akukhulupirira kuti njira zina zochiritsira zothandiza, kupatulapo mankhwala ndi jakisoni a milingo yayikulu ya insulin, kulibe. Chifukwa chake, madokotala akupitilizabe kugwiritsa ntchito mapiritsi ochepetsa shuga omwe samachepetsa kufa. Pa Diabetes-Med.Com mutha kudziwa kuti ndizosavuta bwanji kuthana ndi matenda ashuga amtundu wa 2 popanda zakudya za "njala" ndi jakisoni wa insulin. Palibe chifukwa chomwa mankhwala oyipa, chifukwa mankhwalawa amathandizanso.

• Chithandizo cha matenda oopsa kwa odwala omwe ali ndi mtundu woyamba 1 ndi shuga
• Mapiritsi a Pressure Noliprel - Perindopril + Indapamide

Mapiritsi osinthidwa osinthidwa

Diabeteson MV - mapiritsi osinthidwa amasinthidwe. Chithandizo - gliclazide - chimamasulidwa kwa iwo pang'onopang'ono, osatero nthawi yomweyo. Chifukwa cha izi, kuphatikizika kwa gliclazide m'magazi kumakhalabe kwa maola 24. Imwani mankhwalawa kamodzi patsiku. Monga lamulo, limayikidwa m'mawa. Common Diabeteson (wopanda CF) ndi mankhwala achikulire. Piritsi lake limasungunuka kwathunthu m'matumbo atatha maola awiri ndi atatu. Gliclazide yonse yomwe imakhala imalowa nthawi yomweyo m'magazi. Diabeteson MV imatsitsa shuga bwino, komanso mapiritsi wamba, ndipo zotsatira zake zimatha msanga.

Mapiritsi amasinthidwe amasinthidwe amakono ali ndi phindu lalikulu pamankhwala okalamba. Chachikulu ndichakuti amakhala otetezeka. Diabeteson MV imayambitsa hypoglycemia (kutsitsidwa shuga) kangapo poyerekeza ndi Diabeton wokhazikika komanso zotumphukira zina za sulfonylurea. Malinga ndi kafukufuku, chiopsezo cha hypoglycemia sichidutsa 7%, ndipo nthawi zambiri chimatha popanda zizindikiro. Poyerekeza ndi pobwera kuti mupeze mtundu watsopano wamankhwala, matenda oopsa a hypoglycemia omwe ali ndi vuto losokonezeka samachitika kawirikawiri. Mankhwalawa amalekeredwa bwino. Zotsatira zoyipa zimadziwika mu zosaposa 1% za odwala.

Kuyerekeza kwa Diabeteson MV ndi Mapale Omasulidwa Mwachangu

Mu zolemba m'magazini azachipatala, adziwe kuti molekyulu ya Diabeteson MV ndi antioxidant chifukwa cha kapangidwe kake kapadera. Koma izi zilibe phindu lenileni, sizikhudza kuthandizira kwa chithandizo cha matenda ashuga. Amadziwika kuti Diabeteson MV imachepetsa mapangidwe amwazi m'magazi. Izi zimachepetsa chiopsezo cha stroke. Koma palibe komwe kwatsimikiziridwa kuti mankhwalawa amaperekadi zoterezi. Zoyipa zamankhwala a shuga, zotumphukira za sulfonylurea, zidalembedwa pamwambapa. Mu Diabeteson MV, kutayikira kumeneku sikungatchulidwe pang'ono poyerekeza ndi mankhwala akale. Imakhudzanso pang'ono ma cell a beta a kapamba. Mtundu wa 1 wa inshuwaransi sukutuluka mwachangu.

Momwe mungamwe mankhwalawa

Diabeteson MV imatengedwa kamodzi patsiku, nthawi zambiri imakhala ndi kadzutsa. Piritsi la 60 mg lochekera limatha kugawidwa m'magawo awiri kuti mupeze mlingo wa 30 mg. Komabe, sichitha kutafunidwa kapena kuphwanyidwa. Mukamamwa mankhwalawa, amwe ndi madzi. Webusayiti ya Diabetes-Med.Com imalimbikitsa mankhwala othandizira odwala matenda ashuga amtundu wa 2. Amakulolani kuti musiye matenda a shuga, kuti musayang'anitsidwe ndi zovuta zake. Komabe, ngati mumamwa mapiritsi, tsiku lililonse osapeza mipata. Popanda apo shuga amakwera kwambiri.

Kuphatikiza pa kutenga matenda a shuga, kulekerera mowa kumatha kukulirakulira. Zizindikiro zake ndi kupweteka mutu, kufupika, kupweteka kwam'mimba, mseru komanso kusanza.

Diabetesone imayambitsa hypoglycemia, ndipo mowa umaletsa zizindikiro zake. Izi ndizowopsa! Kukomoka chifukwa cha shuga ochepa kumawoneka ngati kuledzera kwambiri. Chiwopsezo chachikulu cha imfa! Chepetsa kudya kwanu mizimu kapena osamwa konse. Komabe, yesetsani kumwa momwe mungamwere bwino.

Mitengo yotsatira ya sulfonylureas, kuphatikiza Diabeteson MV, si mankhwala oyamba ashuga amitundu iwiri. Mosavomerezeka, ndikulimbikitsidwa kuti odwala azisankhidwa choyamba mapiritsi a metformin (Siofor, Glucofage). Pang'onopang'ono, mlingo wawo umakulitsidwa mpaka pazochulukirapo 2000-3000 mg patsiku. Ndipo pokhapokha ngati izi sizikwanira, onjezerani Diabeteson MV. Madokotala omwe amapereka mankhwala a shuga m'malo mwa metformin amalakwitsa. Mankhwalawa onse akhoza kuphatikizidwa, ndipo izi zimapereka zotsatira zabwino. Kupitilira apo, sinthani ku pulogalamu yachiwiri ya matenda ashuga kukana mapiritsi owononga.

Zomwe zimachokera ku sulfonylureas zimapangitsa khungu kumvetsetsa kwambiri ma radiation ya ultraviolet. Chiwopsezo chowonjezereka cha kutentha kwa dzuwa. Ndikulimbikitsidwa kugwiritsa ntchito ma sunscreens, ndipo ndibwino kuti musayake ndi dzuwa. Ganizirani za chiopsezo cha hypoglycemia chomwe Diabeteson angayambire. Mukamayendetsa kapena kugwira ntchito yoopsa, yesani shuga yanu ndi glucometer mphindi 30-60 zilizonse.

Ndani sakukwanira

Diabeteson MB sayenera kumwedwa kwa aliyense, chifukwa njira zina zochizira matenda amtundu wa 2 zimathandiza komanso sizimayambitsa mavuto. Izi ndizotsutsana ndi boma. Dziwani kuti ndi magulu ati a odwala omwe akuyenera kupatsidwa mankhwalawa mosamala.

Pakakhala pakati komanso poyamwitsa, mapiritsi aliwonse omwe amachepetsa shuga amakhala otsutsana. Diabeteson MV siikuperekedwa kwa ana ndi achinyamata, chifukwa kugwira ntchito ndi chitetezo cha gululi sichinakhazikitsidwe. Musamamwe mankhwalawa ngati m'mbuyomu simunakhale nawo kapena mankhwala ena a sulfonylurea. Mankhwalawa sayenera kumwa ndi odwala omwe ali ndi matenda amtundu woyamba 1, ndipo ngati muli ndi vuto losakhazikika la 2 shuga, nthawi zambiri za hypoglycemia.

Ngati mutsatira zakudya zamafuta ochepa, ndiye kuti pali chiopsezo chowonjezereka chakuti mapiritsi a Diabetes adzayambitsa hypoglycemia. Ndikofunikira kuti muchepetse mulingo, koma ndibwino kusiya zonse. Njira zina zochizira matenda ashuga amtundu wa 2 malinga ndi zakudya zamagulu ochepa a shuga, motero palibe chifukwa chomwa mankhwala oyipa.

Zotumphukira za Sulfonylurea sizingatengedwe mwa anthu omwe ali ndi matenda owopsa a chiwindi ndi impso. Ngati muli ndi matenda ashuga a nephropathy - kambiranani ndi dokotala. Mwambiri, amalangizanso kulowetsa mapiritsiwo ndi jakisoni wa insulin. Kwa anthu achikulire, Diabeteson MV ndiyoyenera ngati chiwindi ndi impso zawo zikuyenda bwino. Mosavomerezeka, zimapangitsa kusintha kwa mtundu wa 2 shuga kukhala mtundu wovuta kwambiri wa insulin wodalira inshuwaransi. Chifukwa chake, odwala matenda ashuga omwe akufuna kukhala ndi moyo wautali popanda zovuta, ndibwino kuti asamwe.

Kodi Diabeteson MV imalembedwa mosamala nthawi ziti?

• hypothyroidism - ntchito yofooka ya chithokomiro komanso kusowa kwa mahomoni ake m'magazi,
• kuchepa kwa mahomoni opangidwa ndi tiziwalo timene timatulutsa timadzi tambiri,
• zakudya zosakhazikika
• uchidakwa.

Diabeteson analogues

Mankhwala oyamba a Diabeteson MV amapangidwa ndi kampani yopanga mankhwala Laboratory Serviceier (France). Kuyambira mu Okutobala 2005, adasiya kupereka mankhwala am'badwo wapitalo ku Russia - mapiritsi a shuga a shuga a 80 mg. Tsopano mutha kugula kokha mapiritsi a Diabeteson MV - mapiritsi otulutsidwa amasinthidwe. Fomu ya Mlingo iyi ili ndi zabwino zake, ndipo wopanga adaganiza zokhazokha. Komabe, gliclazide pamapiritsi otulutsira mwachangu imagulitsidwa. Izi ndi fanizo za Diabetes, zomwe zimapangidwa ndi opanga ena.

Mndandanda wa mankhwala Diabeteson MV

Analogs a mapiritsi a Diabeteson amasulidwe mwachangu

Kukonzekera komwe kaphatikizidwe kake ndi gliclazide mu mapiritsi otulutsira msanga tsopano kwatha. Ndikofunika kugwiritsa ntchito Diabeteson MV kapena mawonekedwe ake m'malo mwake. Chabwinonso chithandizo ndi mtundu wa matenda a shuga a 2 chifukwa chokhala ndi zakudya zamagulu ochepa. Mudzatha kukhala ndi shuga wokhazikika wabwinobwino, ndipo simudzafunika kumwa mankhwala ovulaza.

Diabeteson kapena Maninil - zomwe zili bwino

Gwero la gawoli linali la mutu wakuti "Kuopsa kwa anthu wamba komanso kuwonongeka kwa mtima, komanso kuwonongeka kwamatenda am'mimba komanso ngozi yam'mimba yovuta kwambiri kwa odwala omwe ali ndi vuto la matenda ashuga a 2 malinga ndi mtundu wa kuyamba kwa matenda a hypoglycemic" munkhani ya "Matenda a shuga" 4 4 .9. Olemba - I.V. Misnikova, A.V. Dreval, Yu.A. Kovaleva.

Njira zosiyanasiyana zochizira matenda amtundu wa 2 zimachitika mosiyanasiyana pachiwopsezo cha matenda a mtima, stroko ndi kufa kwathunthu mwa odwala. Olemba nkhaniyo adafufuza zambiri zomwe zidalembedwa mu mbiri ya anthu odwala matenda ashuga a dera la Moscow, omwe ndi gawo la boma lolembetsa matenda a shuga a Russian Federation. Anawunika anthu omwe anapezeka ndi matenda a shuga a 2 mu 2004. Amayerekezera mphamvu ya sulfonylureas ndi metformin ngati amathandizidwa zaka 5.

Zinapezeka kuti mankhwalawa - mankhwala a sulfonylurea - ndizovulaza kuposa zothandiza. Momwe amathandizira poyerekeza ndi metformin:

• chiopsezo cha kufa ndi mtima wonse chidachulukitsidwa,
• kuwopsa kwa mtima
• chiopsezo cha matenda a sitiroko chinakulitsidwa katatu.

Nthawi yomweyo, glibenclamide (Maninil) inali yovulaza kuposa gliclazide (Diabeteson). Zowona, nkhaniyi sichinatchule kuti ndi mitundu iti ya Manilil ndi Diabeteson yomwe imagwiritsidwa ntchito - mapiritsi otulutsidwa kapena ena wamba. Zingakhale zosangalatsa kuyerekezera zomwe zimachitika ndi odwala omwe ali ndi matenda amtundu wa 2 omwe adalandira mankhwala a insulin m'malo mwa mapiritsi. Komabe, izi sizinachitidwe, chifukwa odwala oterowo sanali okwanira. Ambiri mwa odwala amakanika jakisoni jakisoni, motero anapatsidwa mapiritsi.

Mafunso Ofunsidwa Kawirikawiri

A Diabetes adawongolera matenda amtundu wa 2 bwino kwa zaka 6, ndipo tsopano asiya kuthandiza. Anawonjezera mlingo wake mpaka 120 mg patsiku, koma magazi a magazi akadali okwera, 10-12 mmol / l. Chifukwa chiyani mankhwalawa alephera? Kodi atichitira chiyani tsopano?

Diabetesone ndi wochokera ku sulfonylurea. Mapiritsiwa amachepetsa shuga m'magazi, komanso amakhala ndi zovulaza. Pang'onopang'ono amawononga ma cell a pancreatic beta. Pambuyo pa zaka 2-9 za kudya kwawo kwa wodwala, insulini ikusowa kwenikweni m'thupi. Mankhwalawa alephera kugwira ntchito chifukwa maselo anu a beta "atha." Izi zikanachitika kale. Kodi atichitira chiyani tsopano? Kufunika kubaya insulin, palibe njira. Chifukwa muli ndi matenda ashuga amtundu wa 2 adasanduka mtundu waukulu wa shuga. Patani diabeteson, sinthani ku chakudya chochepa chamafuta ndipo mupeze insulin yambiri kuti mukhale shuga wabwinobwino.

Wachikulire wakhala akudwala matenda a shuga 2 amtundu wazaka zisanu ndi zitatu. Shuga wamagazi 15-17 mmol / l, zovuta zopangidwa. Adatenga manin, tsopano adasamukira ku Diabeteson - sizinaphule kanthu. Kodi ndiyambe kumwa amaryl?

Zomwezo ngati wolemba wa funso lakale. Chifukwa chazaka zambiri zosachiritsika bwino, matenda ashuga amtundu wa 2 asintha kukhala mtundu waukulu wa shuga. Palibe mapiritsi omwe angapatsidwe. Tsatirani pulogalamu ya matenda a shuga 1, yambani kubayila insulin. Zochita, nthawi zambiri zimakhala zosavuta kukhazikitsa chithandizo choyenera cha odwala matenda ashuga. Ngati wodwala akuwonetsa kuiwalika ndi kusakhazikika - siyani chilichonse monga momwe ziliri, ndipo dikirani modekha.

Kwa matenda a shuga a 2, adokotala adandiuza 850 mg tsiku lililonse kwa Siofor. Pambuyo pa miyezi 1.5, adasamukira ku Diabeteson, chifukwa shuga sizidagwere konse. Koma mankhwalawa nawonso ndi osathandiza kwenikweni. Kodi ndizoyenera kupita ku Glibomet?

Ngati Diabeteson sachepetsa shuga, ndiye kuti Glybomet sikhala othandiza. Mukufuna kuchepetsa shuga - yambani kubayila insulini. Pa vuto la matenda apamwamba a shuga, palibe njira yina yomwe ingapezeke. Choyamba, sinthani ku chakudya chochepa chamafuta ndikuleka kumwa mankhwala owononga. Komabe, ngati mwakhala muli ndi mbiri yakale ya matenda ashuga amtundu wa 2 ndipo mwathandizidwa molakwika pazaka zapitazi, ndiye kuti mukufunikanso kubaya insulini. Chifukwa chakuti kapamba amatayika ndipo sangathe kupirira popanda kuthandizidwa. Zakudya zamafuta ochepa zimatsitsa shuga wanu, koma osazungulira. Kuti mavutowa asadzayambike, shuga sayenera kupitirira 5.5-6.0 mmol / l 1-2 patatha chakudya komanso m'mawa pamimba yopanda kanthu. Phatikizani pang'onopang'ono insulini pang'ono kuti mukwaniritse izi. Glibomet ndi mankhwala ophatikiza. Zimaphatikizapo glibenclamide, yomwe imakhala ndi zovulaza zofanana ndi Diabetes. Osagwiritsa ntchito mankhwalawa. Mutha kutenga "pure" metformin - Siofor kapena Glyukofazh. Koma palibe mapiritsi omwe angalowe m'malo mwa jakisoni wa insulin.

Kodi ndizotheka ndi mtundu wachiwiri wa shuga kutenga Diabeteson ndi sapxin kuti muchepetse thupi nthawi yomweyo?

Momwe diabeteson ndi sapxin zimalumikizirana - palibe deta. Komabe, Diabetes imalimbikitsa kupanga insulin ndi kapamba. Insulin, nayenso, imasintha shuga kukhala mafuta ndikulepheretsa kuchepa kwa minofu ya adipose. Mokulira kwambiri m'magazi, zimakhala zovuta kwambiri kuchepetsa thupi. Chifukwa chake, odwala matenda ashuga ndi othandxin amakhala ndi zotsutsana. Reduxin amayambitsa mavuto ambiri ndipo chizolowezi chake chimayamba msanga. Werengani nkhani ya "Momwe mungachepetse thupi ndi matenda ashuga a 2." Siyani kumwa Diabeteson ndi sapxin. Sinthani ku chakudya chochepa chamafuta. Amasintha shuga, kuthamanga kwa magazi, cholesterol m'magazi, ndipo mapaundi owonjezera amathanso.

Ndakhala ndikutenga Diabeteson MV kwa zaka 2 kale, kuthamanga shuga kumakhalabe pafupifupi 5.5-6.0 mmol / l. Komabe, chidwi choyaka m'mapazi chayamba posachedwapa