Unitiol wauchidakwa: ntchito
Unitiol ikupezeka mu njira yankho la makonzedwe amkati ndi makonzedwe: omveka, opinki kapena opanda khungu, ndi fungo lochepa wa hydrogen sulfide (5 ml mu galasi ampoules, ma 5 ampoules m'matumba a blister, 2 mapaketi okhala pamakatoni a makatoni).
Muli 1 ml ya yankho:
- yogwira mankhwala: unitiol (dimercaptopropanesulfonate sodium monohydrate) - 50 mg,
- zothandiza: sulfuric acid 0,1 M, Trilon B (disodium edetate), madzi a jakisoni.
Mlingo ndi makonzedwe
Unitiol imayendetsedwa kudzera mu intramuscularly kapena subcutaneally.
- poyizoni wa arsenic: 5-10 ml (5 mg pa 1 makilogalamu a kulemera kwa thupi) katatu pa tsiku loyamba, katatu patsiku lachiwiri komanso nthawi 1-2 patsiku lotsatira,
- poizoni wa zeb: malinga ndi chiwembu pamwambapa, kwa masiku 6 mpaka 7 (mpaka zizindikiro za kuledzera zipere),
- mtima glycoside poyizoni: 5-10 ml ya madzi amchere njira yochepetsa 5% katatu pa tsiku kwa masiku awiri oyamba, ndiye 5-10 ml 1-2 kawiri pa tsiku (mpaka mtima wasowa).
- mpumulo wa Delirium: 4-5 ml ya Unithiol kamodzi,
- Matenda a Wilson-Konovalov: 5-10 ml yankho lamadzi 5% yokhazikika nthawi imodzi tsiku lililonse tsiku lililonse kapena tsiku lililonse, jakisoni 25-30 amafunikira maphunziro amodzi, ngati kuli koyenera, maphunzirowa amabwerezedwa pambuyo pa miyezi 3-4,
- uchidakwa wambiri: 3-5 ml katatu pa sabata.
Unitiol: mitengo pamafakitale apakompyuta
UNITIOL 5% 5ml 10 ma PC. jakisoni yankho
Unitiol 50 mg / ml yankho la makonzedwe amkati ndi ma subcutaneous a 5 ml 10 ma PC.
Unitiol 50 mg / ml yankho la makonzedwe amkati ndi ma subcutaneous a 5 ml 10 ma PC.
Zambiri zokhudzana ndi mankhwalawa ndizofanana, zimaperekedwa pazidziwitso ndipo sizilowa m'malo mwa malangizo ovomerezeka. Kudzipatsa nokha mankhwala kuopsa!
Ku UK, kuli lamulo malinga ndi momwe dokotala wothandizira amatha kukanachita opaleshoni ngati atasuta kapena wonenepa kwambiri. Munthu ayenera kusiya zizolowezi zoipa, kenako, mwina, sangafunikire opareshoni.
Mabakiteriya mamiliyoni ambiri amabadwa, amoyo ndi kufa m'matumbo athu. Amatha kuwoneka pa kukula kwakukulu, koma ngati atakhala palimodzi, akhoza kukhala mu kapu ya khofi yokhazikika.
Vibrator woyamba adapangidwa m'zaka za zana la 19. Adagwira ntchito pa injini yankhonya ndipo adapangira kuti azitsatira khungu la akazi.
Poyesera kuti wodwalayo atuluke, madokotala nthawi zambiri amapita kutali kwambiri. Ndiye, mwachitsanzo, Charles Jensen wina mzaka kuyambira 1954 mpaka 1994. adapulumuka ntchito zopitilira 900 neoplasm.
Zoposa $ 500 miliyoni pachaka zimagwiritsidwa ntchito pa mankhwala azisamba okha ku United States. Kodi mukukhulupilirabe kuti njira yoti mugonjetse ziwengo ikapezeka?
Okonda akapsopsona, aliyense wa iwo amataya 6.4 kcal pamphindi, koma nthawi yomweyo amasinthana mitundu pafupifupi 300 ya mabakiteriya osiyanasiyana.
Mafupa aanthu ndi olimba kwambiri kuposa konkriti.
Mwazi wa munthu "umayenda" m'matumbo omwe akukakamizidwa kwambiri, ndipo ngati umphumphu wake waphwanyidwa, amatha kuwombera mpaka 10 metres.
Nthawi yayitali yotsala ndiyotsika ndi yoyipa.
James Harrison wazaka 74 yemwe amakhala ku Australia amakhala wopereka magazi pafupifupi nthawi 1,000. Ali ndi mtundu wamagazi osafunikira, ma antibodies omwe amathandizira akhanda omwe ali ndi vuto lalikulu la magazi kukhala ndi moyo. Chifukwa chake, waku Australia adapulumutsa ana pafupifupi mamiliyoni awiri.
Mankhwala akutsokomola "Terpincode" ndi amodzi mwa atsogoleri ogulitsa, ayi chifukwa cha mankhwala ake.
Ngati mumamwetulira kawiri kokha patsiku, mutha kuchepetsa kuthamanga kwa magazi ndikuchepetsa chiopsezo cha matenda a mtima ndi stroko.
Poyamba zinkakhala kuti kumatheka kumapangitsa thupi kukhala ndi mpweya wabwino. Komabe, malingaliro awa adatsutsidwa. Asayansi atsimikizira kuti ukamadzuka, munthu amazizira ubongo ndikusintha magwiridwe ake.
Mankhwala ambiri poyamba anali ogulitsidwa ngati mankhwala osokoneza bongo. Mwachitsanzo, a heroin adagulitsidwa ngati mankhwala a chifuwa. Ndipo cocaine adalimbikitsidwa ndi madokotala ngati opaleshoni komanso ngati njira yowonjezerera kupirira.
Ntchito yomwe munthu samakonda imakhala yovulaza psyche yake kuposa kusowa kwa ntchito konse.
Aliyense angathe kukumana ndi vuto lomwe limataya dzino. Izi zitha kukhala njira yomwe madokotala a mano amagwiritsa, kapena zotsatira za kuvulala. M'modzi ndi.
Kutulutsa Fomu
Yankho lomveka, lopanda utoto.
- 5 ml yankho lotere mu ma ampoule, ma ampoules 10 mu phukusi la makatoni.
- 5 ml yankho lotere mu ma ampoule, ma 100 kapena 75 ma bokosoni.
- 5 ml yankho lotere mu ma ampoule, ma ampoules 10 mu paketi yolumikizira - awiri, khumi ndi asanu kapena khumi ndi awiri m'makatoni.
Pharmacodynamics ndi pharmacokinetics
Mankhwala
Unitiol watero kubwezeretsa machitidwe. Amachotsa cholakwika magulu a sulfhydryl. Malinga ndi mtundu wa zochita, ili pafupi ndi ma tata. Magulu a Sulfhydryl chitani ndi Zoyipa za thiol m'misempha ndi m'magazi, ndikupanga zovuta zopanda pake zomwe zimachoka ndi mkodzo. Kuletsa ziphe kumabwezeretsa kugwira ntchito kwa ma enzyme mu maselo omwe akhudzidwa ndi zinthu zoopsa. Amagwiritsidwa ntchito ngati mankhwala oletsa poizoni. zitsulo zolemera, arsenic ndi zida zawo.
Mwa anthu omwe ali ndi sekondale amyloidosis ndi polyneuropathy a matenda ashuga amathandizira kuchepetsa ululu, kusintha magwiridwe amanjenje, amathandizira kutsimikiza kwa capillary.
Pharmacokinetics
Pambuyo pa jakisoni, mamolekyulu a mankhwala amalowerera m'magazi. Kuzindikira kwambiri m'magazi kumajambulidwa theka la ola pambuyo pobayira. Kuchotsa theka moyo ukufika 2 maola. Amayikidwamo mumkodzo, makamaka mu mawonekedwe a zinthu zosakwanira makutidwe ndi okosijeni.
Zizindikiro zogwiritsidwa ntchito
- hepatocerebral dystrophy (Wilson-Konovalov syndrome),
- kuledzerazebwe, arsenic, chromium, bismuthkapena mtima glycosides,
- at uchidakwa matenda osachiritsika ndipo mowa wotsekemeramonga gawo la zovuta mankhwala.
Contraindication
- kulephera kwa chiwindi,
- chidwikwa mankhwala
- wazaka 18
- mimba kapena nyere,
- ochepa matenda oopsa.
Malangizo ogwiritsira ntchito Unithiol (Njira ndi Mlingo)
Malangizo ogwiritsira ntchito Unithiol amawerengera kuti apereke mankhwalawa intramuscularly kapena subcutaneally.
Mankhwalawa kawopsedwe wa arsenic mankhwala kutumikiridwa pa mlingo wa 50 mg yogwira mankhwala pa 10 makilogalamu (250-500 mg), patsiku loyamba limalangizidwa kuperekera mlingo mpaka ma 4, tsiku lachiwiri - mpaka katatu, pamasiku otsatirawa - kamodzi patsiku.
Mankhwalawa poyizoni ndi mchere wa zeb mankhwalawa amagwiritsidwa ntchito malinga ndi chiwembu pamwambapa kapena mpaka zizindikiro za kuledzera zipere.
Mankhwalawa mtima glycoside poyizoni patsiku loyamba ndi lachiwiri, mankhwalawa amaperekedwa pa mlingo wa 50 mg yogwira pa 10 kg wa kulemera (250-500 mg) mpaka kanayi patsiku, patsiku lotsatira - kawiri patsiku mpaka zizindikilo mtima.
Mankhwalawa hepatocerebral dystrophy akulangizidwa kuti mupeze intramuscularly 5-10 ml ya njira yokhazikika yozungulira (50 mg / ml) tsiku lililonse kapena masiku awiri aliwonse, kutalika kwa mankhwalawa nthawi zambiri kumakhala jakisoni 26-30, ngati kuli kotheka, njira ya mankhwalawa imabwerezedwa pambuyo pa miyezi 4.
Unitiol wa uchidakwa
Mankhwalawa uchidakwa wosatha 4-5 ml ya njira yokhazikika ya ndende imayendetsedwa katatu katatu pa sabata.
Pa mankhwala delirium 5 ml ya njira yokhazikika ya ndende ndi jekeseni kamodzi.
Malangizo apadera
Mankhwalawa pachimake poizoni, mankhwalawa mankhwala limodzi ndi zina njira zochizira: oksijeni mankhwala, chapamimba, jakisoni Dextrose.
Unitiol-Binergia, R-X-1, Unitiol-Ferein, Zorex.
Sikugwira ntchito kwa anthu ochepera zaka 18.
Momwe mungagwiritsire ntchito: Mlingo ndi njira ya chithandizo
V / m, s / c. Ndi kuledzera kwa arsenic - 250-500 mg wa mankhwalawa (5-10 ml ya madzi 5% yankho), pamlingo wa 0,05 g / 10 kg, patsiku loyamba - katatu, patsiku lachiwiri - katatu, tsiku lotsatira - Nthawi 1-2. Pankhani ya poyizoni ndi mankhwala a Hg - malinga ndi chiwembu chomwecho masiku 6-7. Chithandizo chimachitika mpaka zizindikiro za kuledzera zipere. Ndi kuledzera kwa digitis, 250-500 mg (5-10 ml ya 5% yankho lamadzi) imayendetsedwa katatu patsiku m'masiku awiri oyambilira, kenako 1-2 kawiri patsiku mpaka zotsatira za mtima zimayima. Ndi hepatocerebral dystrophy - IM 250-500 mg (5-10 ml ya 5% yankho) tsiku lililonse kapena tsiku lililonse, njira ya mankhwalawa - 25-30 jekeseni, ngati pakufunika, bwerezerani pambuyo pa miyezi 3-4. Pazakumwa zoledzeretsa, 150-250 mg (3-5 ml ya 5% yankho) imayikidwa katatu pa sabata. Poyimitsa delirium - kamodzi 200-250 mg (4-5 ml ya 5% yankho). Pa matenda ashuga polyneuropathy - iv, 250 mg (5 ml ya 5% yankho), njira ya mankhwalawa ndi majakisoni 10.
Mkati, mphindi 30 musanadye, ndi madzi pang'ono.
Alcohol achire matenda, poyizoni ndi As mankhwala ndi mchere wa zitsulo zolemera: 250-500 mg (1-2 makapisozi) patsiku, ngati kuli kotheka, mlingowo ukhoza kuwonjezeka mpaka 750 mg (3 makapisozi) patsiku, wogawidwa pamiyeso ingapo. Chithandizo chimachitika mpaka zizindikiro za kuledzera zipere.
Kuledzera kosatha: 500 mg ya mankhwalawa (makapisozi 2) kawiri pa tsiku monga gawo la zovuta mankhwala.
Diabetesic polyneuropathy: 250 mg (1 kapisozi) patsiku kwa masiku 10.
Zotsatira za pharmacological
Wothandizika ndi zovuta, amakhala ndi zotsatsa. Magulu a yogwira sulfhydryl, omwe amalumikizana ndi ziphe za thiol ndikupanga zinthu zopanda poizoni ndi iwowo, kubwezeretsa ntchito zamagulu a enzyme a thupi omwe akhudzidwa ndi poizoni. Kuchulukitsa kuchulukitsidwa kwa ma cations ena (makamaka Cu2 + ndi Zn2 +) kuchokera kuma enzyme okhala ndi zitsulo.
Mu matenda a diabetesic polyneuropathy, amachepetsa ululu wosakwiya, amasintha mawonekedwe a zotumphukira zamitsempha ndipo amatithandizanso kupezekanso kwakanthawi kachulukidwe ka capillaries.
Kufotokozera zamankhwala ndi kapangidwe kake
"Unithiol" ndi mankhwala omwe amagwiritsidwa ntchito kwambiri poizoni. Chifukwa cha zomwe zimapangidwa, zimathandiza thupi kuthana ndi poyizoni, kuchotsa zodetsa zoyipa kuchokera pamenepo.
Mankhwalawa amapangidwa ngati njira yothetsera vutoli, yomwe imapangidwira kukhazikitsidwa kwa minofu kapena pansi pa khungu. Unitiol ndi mankhwala. Mankhwala akalowa m'thupi, amayamba kuyanjana ndi poizoni. Amawalumikiza, amawasandutsa malo otetezedwa omwe sawopseza anthu, ndikuwachotsa m'thupi.
Mankhwala amapezeka mu ampoules, momwe aliyense mamililita asanu a njira. Mulinso:
Kumwa mankhwala osokoneza bongo
"Unitiol" uchidakwa nthawi zambiri umadziwika. Ngakhale zili choncho, sindiwo chithandizo chachikulu cha vutoli, ndipo sichikhumudwitsa mtima wofuna kumwa mowa. Mankhwala amaperekedwa limodzi ndi othandizira ena.
Unitiol imayikidwa chifukwa chakuti ethyl mowa ndi poizoni wamphamvu. Ndi kulowetsedwa kwawo pafupipafupi m'thupi, ndipo ngakhale kuchuluka kwambiri, kudzikundikira kwa poizoni kumachitika, zitsulo zolemera zimasungidwa. Ichi ndi katundu wamkulu kwa iye.
Mankhwalawa amalembedwa kwa anthu omwe amadalira mowa kuti:
- Kuteteza ndi, ngati kuli kotheka, kubwezeretsanso dongosolo lamanjenje, lomwe makamaka limakhala ndi kumwa pafupipafupi. Mankhwala amasunga kuchuluka kwa magulu a sulfide pamlingo woyenera. Zimakhala ndi zotheka ku ma neuron ndi machitidwe awo, chifukwa zimathandizira umphumphu wawo ndikulola kuti zizigwira bwino ntchito.
- Pewani maonekedwe a mowa. Anthu ambiri omwe amamwa mowa pafupipafupi ndipo kwa nthawi yayitali amakhala ndi zowonera. Izi zimachitika, monga lamulo, pamaziko a kukana kwambiri zakumwa zoledzeretsa. Munthawi yowoneka ngati delirium, munthu amakhala wowopsa pagulu ndipo amatha kudzipweteka.
Yang'anani! Ndikofunika kudziwa kuti "Unithiol" sigwiritsidwa ntchito pothandiza kutsekeka kwa matenda a hangover kapena ngati mankhwala a poizoni. Komanso, ngati mumamwa nthawi yomweyo ndi mowa, mutha kuyambitsa poizoni.
Mankhwala ayenera kuyang'aniridwa ndi dokotala. Chifukwa chake, jakisoni woyamba akulimbikitsidwa kuti akaperekedwe kwa katswiri kuchipatala. Izi zipangitsa kuti thupi lizindikira momwe mankhwalawo amachitikira, ndipo ngati thupi lawo siligwirizana, perekani chithandizo kwa wodwalayo.
Mukamayimitsidwa kwa ma milliliters 4-5 a 5% amathandizira kamodzi
Mankhwala ena amatha kuchitika kunyumba. Pankhaniyi, ndikofunikira kuwonetsetsa mosamala mlingo wa mankhwalawa, womwe adokotala amauza wodwala aliyense payekhapayekha.
Wopanda uchidakwa, wodwalayo nthawi zambiri amapatsidwa jekeseni 2-3 mkati mwa sabata. Nthawi imodzi, 3 mpaka 5 mamililita a 5% yankho. Pankhaniyi, "Unithiol" imagwira ntchito ngati mankhwala owonjezera pakuchotsa zovuta zakumwa zoledzeretsa.
Mukayimitsa kukonzekera kwa 4-5 mamililita 5% yothetsera imayambitsidwa kamodzi.
Zotsatira za kumwa mankhwalawa komanso zoyipa
Unitiol imawonetsa zotsatira zabwino pakuthandizira uchidakwa. Imatha kuyeretsa thupi la poizoni, kuletsa poizoni wake ndikutchingira dongosolo lamanjenje kuti lisawonongeke. Pankhani imeneyi, ndemanga za iye ndizabwino.
Koma zimachitikanso kuti mankhwalawa amagwiritsa ntchito bwino kuvulaza thupi la munthu. Monga lamulo, izi zimachitika chifukwa chakuti kuchuluka kwa yankho lomwe adawonetsa adotolo sikunawonedwe. Pankhaniyi, mutha kukumana ndi mankhwala osokoneza bongo owopsa, omwe amadziwika ndi izi:
- Kupuma movutikira, kupuma movutikira. Zimakhala zovuta kuti munthu atulutse mpweya ndi kutulutsa mpweya. Amamva kuperewera kwa mpweya, motero amapuma yambiri, yomwe nthawi zina imatha kufika 20 pamphindi imodzi.
- Chifukwa chakuti kupuma movutikira kumachitika, ndipo magazi amathanso kusokonezeka, khungu limakhala lotuwa, ndipo milomo ndi miyendo zimatha kutembenukira kwamtambo.
- Kusweka kwa mtima kumapitilizidwa, tachycardia imachitika. Nthawi zina, zimachitika kuti zimachitika pang'onopang'ono.
- Mikwingwirima imapezeka m'miyendo, nthawi zambiri imatha kupindika.
- Munthu amakhala wopanda nkhawa ndipo akhoza kugwa.
Zotsatira za kuchuluka kwa mankhwala osokoneza bongo ndi zovuta kwambiri. Ngati, jakisoni atayambitsidwa, zosintha pamwambazi zikuyamba kuwonekera m'thupi, ndikofunikira kudziwitsa dokotala posachedwa - ngati muli kuchipatala. Ngati chithandizo chikuchitika kunyumba, muyenera kuyimbira ambulansi nthawi yomweyo.
Kunyalanyaza zizindikiritso za mankhwala osokoneza bongo, kusowa kwa chithandizo chakanthawi kumatha kubweretsa imfa.
Zotsatira zoyipa zimachitikanso chifukwa cha tsankho la munthu payekha. Pankhaniyi, zizindikiro zotsatirazi zingaoneke:
- Chotupa cha khungu lawo siligwirizana kapena edema ya Quincke.
- Kusanza mseru, kusanza kumawonekera.
- Amayamba kudwala kapena chizungulire.
- Pali kufooka.
- Khungu limakhala lofiirira.
- Pafupipafupi kugunda kwamtima kumachuluka.
Ngati zizindikiro zotere zikuwoneka, muyenera kukana kumwa mankhwalawo mopitilira. Monga lamulo, izi ndizokwanira kusintha matupi athu.
Zotsatira za kuchuluka kwa mankhwala osokoneza bongo ndi zovuta kwambiri
Zingati kuchuluka kwa mankhwalawo
"Unithiol" ndi mankhwala otsika mtengo, kuwonjezera apo, sizovuta kugula. Kuchita izi ndikulimbikitsidwa m'masitolo odalirika omwe amagulitsa mankhwala apamwamba omwe ali ndi zolembedwa zonse zofunika.
Mankhwala osavomerezeka kwenikweni sangakupatseni chithandizo. Choyipa chachikulu, kubodza kumatha kuvulaza thupi la munthu womwa, komanso kupha.
Mtengo wa mankhwalawo m'mafakisi ku Russia ndi wochokera pa ma ruble 290 mpaka 500.
Unitiol ndi njira yodziwikiratu. Sizothandiza kuti mankhwalawa azidalira mowa, komanso limapatsidwa mitundu ina ya poizoni. Mankhwala amathandizira kuchotsa m'thupi:
- Arsenic
- Mchere wamchere wachuma.
- Mtima glycosides.
Kufotokozera, kapangidwe, kapangidwe ka mankhwalawo ndikunyamula kwake,
Kodi mankhwalawa "Unithiol" amapezeka mu mankhwala ati? Malangizo ogwiritsira ntchito (mankhwalawa sagwiritsidwa ntchito pamapiritsi) akuwonetsa kuti wothandizirayo amapezeka mwanjira yankho lomveka bwino, lomwe limapangidwira subcutaneous kapena intramuscular management. Imakhala ndi fungo lokomoka la hydrogen sulfide, komanso mtundu wofiirira wa pinki (ukhoza kukhala wopanda mtundu).
Kodi ndi ziti zomwe zikukonzekera Unithiol? Malangizo ogwiritsira ntchito akuti othandizira omwe amapangidwira ndi sodium dimercaptopropanesulfonate monohydrate. Komanso mankhwalawa amaphatikiza mankhwala othandizira mu mawonekedwe a sulfuric acid, disodium edetate (Trilon B) ndi madzi a jakisoni.
Pogulitsa, mankhwalawa amabwera m'magalasi 5 agalasi. Zadzaza m'maselo a contour, omwe amawaika m'miyala.
Mankhwala a Pharmacodynamic
Kodi mankhwala a Unitiol amagwira ntchito bwanji? Malangizo ogwiritsira ntchito amadziwitsa kuti ndiwothandiza kuti azichotsa zinthu zomwe zimachotsa mofulumira kuperewera kwamagulu a sulfhydryl. Mwanjira yake, mankhwalawa ali pafupi kwambiri ndi ma complexones.
Malinga ndi akatswiri, magulu a sulfhydryl amatha kuthana ndi poizoni wa thiol m'magazi ndi zimakhala, pomwe amapanga zovuta zopanda pake zomwe zimatuluka ndi mkodzo.
Kuletsa ziphe kumathandiza kubwezeretsa ntchito mu ma enzyme onse omwe ali m'maselo omwe akhudzidwa ndi zinthu zoopsa. Mankhwalawa amagwiritsidwa ntchito ngati mankhwala oletsa poizoni ndi arsenic, zitsulo zolemera ndi mankhwala ake.
Mwa anthu omwe ali ndi polyneuropathy a matenda ashuga komanso ndi amyloidosis yachiwiri, mankhwalawa amachepetsa ululu, amasinthira magwiridwe a NS, komanso amawongolera kuchuluka kwa capillaries.
Mawonekedwe a Kinetic
Kodi ndi mankhwala ati a kinetic omwe amapezeka mu mankhwala a Unithiol? Malangizo ogwiritsira ntchito akuti pambuyo pobowola kapena kulowerera mkati, ma mamolekyulu a mankhwala amalowa m'magazi. Kuphatikizika kwakukulu kwa mankhwalawa kulembedwa pambuyo pafupifupi mphindi 40 (pambuyo poyang'anira i / m).
Hafu ya moyo wa mankhwalawa ndi maola awiri. Mankhwalawa amachotseredwa limodzi ndi mkodzo monga mawonekedwe a zinthu zosakwanira makutidwe ndi okosijeni.
Zizindikiro zothetsera
Kodi wodwala angalembe mankhwala a Unithiol ngati akuwonetsa kuti? Malangizo ogwiritsira ntchito (jakisoni amayenera kuchitika kokha ndi akatswiri odziwa ntchito zachipatala) akuwonetsa kuti chida ichi chimagwiritsidwa ntchito:
- kuledzera ndi bismuth, arsenic, chromium, mercury kapena glycosides wamtima,
- uchidakwa wopitilira muyeso monga mankhwala osakanikirana,
- hepatocerebral dystrophy (Wilson-Konovalov syndrome).
Mankhwala "Unithiol": malangizo ogwiritsira ntchito
Mu ma ampoules, chida ichi chitha kugulidwa ku pharmacy iliyonse. Malinga ndi malangizo, mankhwalawa amayenera kuperekedwa kudzera mwa mankhwalawa kapena mu mnofu.
Mankhwala a kuledzera kwa arsenic, mankhwalawa amagwiritsidwa ntchito pa 50 mg ya yogwira pophika pa 10 kg ya kulemera kwa ozunzidwa (ndiye 250-500 mg). Patsiku loyamba la chithandizo, mulingo woyenera uyenera kutumikiridwa mpaka 4, kwachiwiri - mpaka katatu, komanso nthawi ina.
Pochiza poyizoni wokhala ndi mchere wa mankhwala a zebas, mankhwalawa amagwiritsidwa ntchito malinga ndi chiwembu pamwambapa masiku 7 kapena mpaka zizindikiro za kuledzera zithe.
Mankhwalawa poizoni wa mtima glycoside tsiku loyamba ndi lachiwiri, mankhwalawa amaperekedwa pa mlingo wa 50 mg wa yogwira gawo pa 10 kg ya kulemera kwa wodwalayo (i.e. 250-500 mg) kanayi pa tsiku, ndipo tsiku lotsatira kawiri kapena mpaka zizindikiro za mtima zimatha.
Mankhwala a hepatocerebral dystrophy, mankhwalawa amaperekedwa kudzera mu mnofu wa 5-10 ml pa ndende yokhazikika tsiku lililonse kapena masiku awiri pambuyo pake. Kutalika kwa mankhwala ndi jakisoni 26-30. Ngati akufunika, maphunzirowo abwerezedwa pambuyo pa miyezi 4.
Zochizira matenda osokoneza bongo osokoneza bongo, mankhwalawa amagwiritsidwa ntchito kuchuluka kwa 4-5 ml mu ndende yokhazikika mpaka katatu pa sabata.
Mankhwalawa delirium, mankhwalawa amaperekedwa kamodzi (5 ml mu ndende yofananira)
Kugwiritsa ntchito mankhwala osokoneza bongo kwambiri
Pakakhala bongo, wodwalayo amakhala ndi kufupika, ma hyperkinesis, ulesi, kupsinjika ndi kupha mphamvu. Pankhaniyi, chithandizo chamankhwala chimachitika.
Mankhwalawa ndi osagwirizana ndi mankhwala omwe amaphatikiza zitsulo zolemera, komanso alkalis. Komanso, sanasankhidwe ndi "Atsizol."
Ndemanga za ogwiritsa ntchito zofunsidwa ndizosowa kwambiri. Izi ndichifukwa choti mankhwalawa amagwiritsidwa ntchito makamaka pakukonzekera.
Ponena za madokotala odziwa ntchito, amalankhula za Unitiol yankho ngati chida chothandiza komanso chothandiza kwambiri chomwe chimachotsa poizoni, kuphatikizira poizoni.
Pharmacokinetics
Kuzindikira kwakukulu mu plasma ya magazi kumafika pakapita mphindi 15-30 pambuyo pa jekeseni wamitsempha. Mankhwalawa amagawidwa makamaka m'magazi am'madzi (madzi a m'magazi). Kuthetsa theka-moyo ndi maola 1-2. Chodzikondweretsa ndi impso, makamaka mu mawonekedwe a zinthu zosakwanira kapena zowonjezera makutidwe ndi okosijeni, pang'ono osasinthika. Sichikupanga.
Mlingo ndi makonzedwe
Mankhwala poyizoni wambiri komanso wosapweteka wa mankhwala a arsenic ndi zebury Unitiol imayendetsedwa intramuscularly kapena subcutaneously (5-10 ml ya yankho la 50 mg / ml). Chithandizo chiyenera kuyambitsidwa koyambirira. Pakakhala poizoni ndi mankhwala osakanikirana ndi arsenic, jakisoni amapangidwa maola angapo aliwonse a 6-8 patsiku loyamba, jakisoni 2-3 tsiku lililonse kwa maola 8 mpaka 12, jekeseni wa 1-2 tsiku lotsatira.
At mankhwala oopsa a zeb Chithandizo chikuchitika chimodzimodzi Mlingo kwa masiku osachepera 6.
At mtima glycoside poyizoni M'masiku awiri oyamba, 5 kapena 10 ml ya yankho la 50 mg / ml unitiol imayendetsedwa kudzera mu mnyozo kapena modutsa. Kumayambiriro kumachitika katatu pa tsiku, ndiye kuti 1-2 pa tsiku mpaka zotsatira za mtima zimatha.
At hepatocerebral kuwonongeka sankha intramuscularly 5-10 ml ya yankho la 50 mg / ml tsiku lililonse kapena masiku ena onse, maphunzirowo ndi 25-30 jakisoni wopuma pakati pa maphunziro a miyezi 3-4.
At matenda ashuga polyneuropathy Ikani 5 ml ya yankho la 50 mg / ml kwa masiku 10.
At uchidakwa wosatha jekeseni intramuscularly 3-5 ml ya yankho la 50 mg / ml 2-3 pa sabata.
Njira zopewera kupewa ngozi
Kukhazikitsidwa kwa unitiol mu poyizoni wakupha sikumapatula kugwiritsa ntchito njira zina zochiritsira (chapamimba cham'mimba, kupuma kwa okosijeni, makonzedwe a shuga).
Gwiritsani ntchito ana. Palibe zambiri pazokhudza kugwiritsa ntchito mankhwalawa Unithiol mwa ana.
Kukopa pa kuyendetsa magalimoto ndi njira zina zowopsa. Chifukwa cha chiwopsezo chakusokonezeka mukamagwiritsa ntchito Unitiol (chizungulire, kuchuluka kwa magazi, tachycardia), munthawi yamankhwala, munthu ayenera kupewa kuyendetsa galimoto komanso kuchita nawo zinthu zomwe zimafunikira kuti anthu azisamala.