Zoyenera kusankha: Fraxiparin kapena Clexane?

Ndi kukhudzika kowonjezereka kwa magazi, ma anticoagulants amagwiritsidwa ntchito popewa magazi. Mankhwalawa ali ndi nyimbo zosiyanasiyana komanso njira zake. Odwala nthawi zambiri amafunsa kuti asankhe chiyani, Fraxiparin kapena Clexane. Kuwunika kwa ma anticoagulants awiri kungathandize kumvetsetsa kuti ndi mankhwala ati omwe ali oyenera panthawi inayake.

Khalidwe la Clexane

Mankhwala ali ndi izi:

1. Kutulutsa mawonekedwe ndi kapangidwe kake. Clexane amapezeka ngati jekeseni, womwe ndi wopanda khungu, wopanda madzi. Mankhwalawa amamuunjikira syringes ya 0,5 ml. Syringe iliyonse imakhala ndi 2040, 60, 80, kapena 100 mg ya enoxaparin sodium ndi madzi a jakisoni. Ampoules amaperekedwa m'maselo apulasitiki a 2 ma PC.
2. Zotsatira za pharmacological. Sodium ya Enoxaparin imagwiritsa ntchito XA, kuletsa kusintha kwa prothrombin kukhala thrombin. Zochita zina zomwe zimagwira ntchito zadziwika - kuponderezana kwa kupanga kwa oyimira pakati otupa ndi kusintha kwa mkhalidwe wamakhoma wamitsempha. Mankhwala amathandizira kupanga minyewa yolepheretsa minyewa ndipo amachepetsa mphamvu yotulutsidwa kwa ve Willebrand factor kuchokera pachiwindi. Zochita izi zimapereka ntchito zapamwamba kwambiri za Clexane. Kugwiritsa ntchito mankhwalawa kumathandizira kuchepetsa nthawi ya prothrombin komanso kuchuluka kwa kuphatikiza kwa maselo ambiri.
3. Kubzala, kugawa ndi kuchotserera. Mphamvu ya anticoagulant ya mankhwalawa imayamba pambuyo pake pakatha maola 3-5. Mu chiwindi, sodium ya enoxaparin imasinthidwa kukhala ochepa maselo kulemera metabolites ndi otsika pharmacological ntchito. Hafu ya moyo wophatikizira imatenga maola 5. Enoxaparin ndi ma metabolites ake amasiya thupi ndi mkodzo.
4. Zizindikiro zogwiritsidwa ntchito. Clexane amagwiritsidwa ntchito popewa komanso kuchiza matenda oopsa a vein thrombosis mwa odwala omwe ali ndi chiopsezo chapakati komanso choopsa. Zisonyezero zakukhazikitsidwa kwa mankhwalawa ndi: kuchira kwa mafupa ndi maopaleshoni ena ambiri, ma thrombosis odwala ogona, thromboembolism yam'mitsempha yam'mapapo. Clexane angagwiritsidwe ntchito kuteteza magazi kuundana ndi mtima kudzera mu hemodialysis. Mankhwala amachepetsa chiopsezo cha kufa myocardial infarction komanso angina osakhazikika.
5. Contraindication Clexane sangathe kuthandizira ngati thupi limagwirizana ndi enoxaparin, magazi mkati, hemorrhagic stroke, kuchuluka kwa zilonda zam'mimbazi, ma opaleshoni am'mbuyomu am'mitsempha, varicose mitsempha. Mochenjera, mankhwalawa amagwiritsidwa ntchito pakukha magazi, zotupa ndi zotupa m'matumbo am'mimba pakukhululuka, sitiroko, kuchira pambuyo pobadwa mwana, mtundu 2 matenda a shuga. Chitetezo cha mankhwalawa kwa ana sichimatsimikiziridwa, chifukwa chake sichimalamulidwa kwa odwala omwe ali ndi zaka 18.
6. Njira yogwiritsira ntchito. Mankhwalawa amaperekedwa mosavuta. Mlingo umakhazikitsidwa ndi mtundu wa matenda komanso chikhalidwe cha thupi. Ndi thrombophilia, 20 mg ya enoxaparin imayendetsedwa tsiku. Pofuna kupewa thrombosis ya postoperative, jakisoni woyamba wa Clexane amapatsidwa maola awiri isanachitike. Njira ya mankhwalawa imatenga masiku 10, ngati kuli kotheka, pitilizani mpaka magazi atasintha.
7. Kuyanjana kwa mankhwala osokoneza bongo. Clexane sangathe kugwiritsidwa ntchito limodzi ndi mankhwala omwe si a antiidalidal anti-yotupa, thrombolytics, acetylsalicylic acid. Mosamala, anticoagulant imagwiritsidwa ntchito molumikizana ndi clopidogrel, ticlopidine, ndi dextran. Mukamagwiritsa ntchito Clexane osakanikirana ndi kashiamu, kuyezetsa magazi pafupipafupi ndi mkodzo kumafunikira.
8. Zotsatira zoyipa. Kugwiritsa ntchito Mlingo wambiri wa mankhwalawa kungathandizire kukulitsa magazi mkati, limodzi ndi kuchepa kwa magazi, kutsika kwa khungu, kufooka kwa minofu. Pa mankhwala, thupi lawo siligwirizana angafike pakhungu kuyabwa, urticaria, kutupa kwa nkhope ndi larynx. Ndi subcutaneous makonzedwe a Clexane, hematomas ndi kulowetsedwa amatha kupanga.

Makhalidwe a Fraxiparin

Makhalidwe otsatirawa ndi omwe ali ndi fakitiramu:

1. Kutulutsa mawonekedwe ndi kapangidwe kake. Ma anticoagulant amapezeka mu mawonekedwe a yankho la subcutaneous makonzedwe. Ndi madzi oyera, achikasu, osununkhira bwino. Mankhwalawa amaperekedwa mu ma syringes a galasi 0.4 ml. Syringe iliyonse imakhala ndi 3800, 5700 kapena 7600 IU ya anti-Xa nadroparin calcium, calcium hydroxide, kuchepetsa hydrochloric acid.
2. Zotsatira za pharmacological. Kashiamu nadroparin amamangika ku plasma chigawo cha antithrombin, ndikuthandizira kuchepetsa factor Xa. Izi zikufotokozera ntchito yapamwamba ya antithrombotic. Poyerekeza ndi heparin, nadroparin sakhala ndi tanthauzo lambiri pokhudzana ndi kuphatikizana kwa maselo am'mimba komanso hemostasis yoyambirira. Mukamagwiritsa ntchito Mlingo wapakatikati, Fraxiparin sichepetsa nthawi ya prothrombin. Ndi ntchito, mankhwalawa amapeza nthawi yayitali.
3. Pharmacokinetics Ndi subcutaneous makonzedwe, zochita zapamwamba za antithrombotic zimayamba pambuyo pa maola 3-4. Nadroparin imakamizidwa pafupifupi kwathunthu. Mothandizidwa ndi mtsempha wamitseko, Fraxiparin imachitika pakatha mphindi 10. Mu chiwindi, nadroparin amasinthidwa kukhala ma metabolites osagwira omwe amatsitsidwa ndi impso. Kuchotsa theka moyo kumatenga maola 3.5.
4. Zizindikiro zogwiritsidwa ntchito. Mankhwalawa amagwiritsidwa ntchito kuti ateteze thromboembolism pachitetezo cha opaleshoni, mtima ndi kupuma. Kukhazikitsa kwa Fraxiparin pa hemodialysis kumalepheretsa magazi kuundana. Ma anticoagulant ndi gawo limodzi la mitundu yovuta yochizira yotsatsira myocardial infarction ndi angina osakhazikika. Mankhwalawa amatha kugwiritsidwa ntchito pokonzekera amayi omwe ali ndi vuto la thrombophilia.
5. Contraindication Mankhwalawa sagwiritsidwa ntchito kwa thrombocytopenia chifukwa cha kugwiritsa ntchito heparin-anticoagulants, kutulutsa magazi mkati, hemorrhagic syndrome, intracranial hemorrhage, kulephera kwambiri kwaimpso, endocarditis ya pachimake. Mankhwalawa sanatchulidwe kwa ana ndi achinyamata ochepera zaka 18. Mosamala, Fraxiparin imathandizira matenda a chiwindi, matenda oopsa, zilonda zam'mimba, komanso kutopa kwa thupi. Pochiza matenda ashuga, boma la ziwiya zoperekera ndalama liyenera kuyang'aniridwa.
6. Njira yogwiritsira ntchito. Mankhwala chikuyendetsedwa mu udindo supine mu subcutaneous minofu ya anterior m'mimba khoma. Musanagwiritse ntchito Fraxiparin, simukuyenera kuchotsa thovu m'mweya ku syringe. Singano imayilowetsedwa kumakona amanja mu khola la khungu. Tsamba la jakisili silifunikira kuti lizipukutidwa.
7. Kuyanjana kwa mankhwala osokoneza bongo. Mukagwiritsidwa ntchito limodzi ndi ACE inhibitors, okodzetsa ndi mchere wa potaziyamu, hyperkalemia imatha kukulira. Kugwiritsa ntchito palimodzi ndi antiplatelet othandizira kumawonjezera mwayi wokhetsa magazi. Mosamala, Fraxiparin imalembedwa kwa odwala omwe amamwa glucocorticosteroids.
8. Zotsatira zoyipa. Zotsatira zoyipa kwambiri zamankhwala ndizopopa zamitundu ingapo, kutsika kwa kuchuluka kwa maselo othandiza magazi kuundana. Zotsatira zoyipa ndizovuta za necrosis pa malo a jekeseni, omwe amatsogozedwa ndikupanga kulowetsedwa.

Kuyerekezera Mankhwala

Maanticoagulants ali ndi mawonekedwe apadera komanso osiyana.

Kufanana pakati pa Clexane ndi Fraxiparin kuli m'mbali zotsatirazi:

• mtundu wa zogwira ntchito (zonse za enoxaparin ndi nadroparin ndizochepa kwambiri za ma heparin),
• Zizindikiro zodzigwiritsira ntchito,
• kuthekera kwa kugwiritsidwa ntchito pakukonzekera ndi kuyang'anira
• Fomu yotulutsa (onse mankhwalawa akupezeka ngati njira yothetsera ma subcutaneous management),
• contraindication ambiri ndi zoyipa.

Kusiyana pakati pa mankhwalawa kuli kuchuluka ndi ntchito ya yogwira ntchito.

Malingaliro a madotolo

Sergey, wazaka 44, Moscow, Hematologist: "Clexane ndi Fraxiparin amagwiritsidwa ntchito kuti achepetse magazi. Izi zimathandiza kupewa kutulutsa kwamitsempha yamaitsempha komanso kutsekeka kwa mitsempha ya m'mapapo mwa odwala omwe ayenera kutsatira kupumula kwa bedi. Fraxiparin ndi mankhwala otetezeka, amagwiritsidwa ntchito Clexane ikhoza kuyambitsa zovuta zingapo, choncho ziyenera kugwiritsidwa ntchito moyang'aniridwa ndi dokotala. "

Tatyana, wazaka 55, Togliatti, dokotala wazachipatala: "Clexane ndi Fraxiparin nthawi zambiri amalembedwa panthawi yakukonzekera. Mankhwalawa ndi othandiza komanso osavuta kugwiritsa ntchito. Ndimaona kuti ndikufunika ndikulowetseni khoma lakumbuyo yam'mimba ndikubwezera kwa mankhwala onse awiri, omwe amachititsa kupweteka kwambiri. "Fraxiparin imagonjera bwino thupi ndipo imayikidwa pambuyo pathupi."

Syringe imodzi imakhala, kutengera mtundu: 10000 anti-Ha ME, 2000 anti-Ha ME, 8000 anti-Ha ME, 4000 anti-Ha ME kapena 6000 anti-Ha ME enoxaparin sodium.

Pharmacodynamics ndi pharmacokinetics

Clexane INN (dzina losavomerezeka padziko lonse lapansi) enoxaparin. Mankhwalawa ndi ochepa molekyulu ndi kulemera molemera pafupifupi ma 4 500 dalton. Kupezeka ndi zamchere hydrolysis heparin benzyl etheryotengedwa kuchokera ku matumbo a nkhumba.

Mukamagwiritsa ntchito mankhwala a prophylactic, mankhwalawa amasintha pang'ono APTTV, ilibe vuto lililonse pakumanga kwa michere ndi micrinogen. Mu achire Mlingo enoxaparin zimawonjezeka APTTV 1.5-2.2 nthawi.

Pambuyo mwadongosolo subcutaneous jakisoni enoxaparin sodium 1.5 mg pa kilogalamu ya kulemera kwa thupi kamodzi patsiku, ndendezo yofanana imachitika pambuyo masiku awiri. The bioavailability ndi subcutaneous makonzedwe ukufika 100%.

Sodium Enoxaparin zimapukusidwa mu chiwindi ndi kuwonongedwa ndi depolymerization. Zotsatira zake metabolites zimakhala ndi ntchito zochepa kwambiri.

Kutha kwa theka-moyo ndi maola 4 (kayendetsedwe kamodzi) kapena maola 7 (maulamuliro angapo). 40% ya mankhwalawa amamuchotsa impso. Kuswana enoxaparin okalamba odwala, kuchedwa ndi vuto laimpso.

Anthu omwe ali ndi vuto la impso, chilolezo enoxaparin yafupika.

Zizindikiro zogwiritsidwa ntchito

Mankhwalawa ali ndi zotsutsana zotsatirazi:

• kupewa ndi embolism mitsempha atachitidwa opaleshoni,
• Chithandizo chovuta kapena chosavuta,
• kupewa thrombosis ndi embolism ya mitsempha mwa anthu omwe amakhala pakama nthawi yayitali chifukwa cha achire othandizira odwala kulephera kwa mtimazolemetsa matenda, kulephera kupumalakuthwa matenda amisala),
• kupewa thrombosis mu njira yamagazi amkati,
• mankhwala popanda Q wave,
• pachimake mankhwala vuto la mtima ndi kuchuluka kwa ST kwa anthu omwe akufunika chithandizo chamankhwala.

Contraindication

• kwa zigawo zikuluzikulu za mankhwalawo, ndi zina zama cell ochepa.
• Matenda okhala ndi chiopsezo chowonjezeka magazi, monga kumuopseza kuchotsa m'mimba, magazi, hemorrhagic.
• Kugwiritsa ntchito Clexane pa nthawi yomwe ali ndi pakati mwa amayi omwe ali ndi ma valves oyenda mtima.
• Zosakwana zaka 18 (chitetezo ndi kuchita bwino sizinakhazikitsidwe).

Gwiritsani ntchito mosamala pazochitika zotsatirazi:

• matenda limodzi ndi matenda a heestatic (hemophilia, hypocoagulation, thrombocytopenia, von Willebrand matenda) ofotokozedwa vasculitis,
• zilonda zam'mimba kapena zilonda zam'mimba, zotupa ndi zotupa zam'mimba,
• posachedwa ischemic,
• zolemetsa
• hemorrhagic kapena matenda ashuga retinopathy,
• woopsa
• kubadwa kwaposachedwa
• kulowererapo kwaposachedwa kwamitsempha kapena kwamaso,
• kukwaniritsidwa zamatsenga kapena opaleshoni ya msanacn kotupa,
• bakiteriya
• intrauterine kulera,
• pericarditis,
• kuwonongeka kwa impso kapena chiwindi
• kuvulala kwambiri, mabala otseguka,
• kuphatikiza limodzi ndi mankhwala okhudza he hetatic dongosolo.

Zotsatira zoyipa

Monga momwe zimakhalira ndi anticoagulants ena, pamakhala chiopsezo chotaya magazi, makamaka ndi njira zowukira kapena kugwiritsa ntchito mankhwala omwe amakhudza hemostasis. Ngati magazi atapezeka, siyani kupereka mankhwalawo, pezani chomwe chikuyambitsa, ndikuyamba chithandizo choyenera.

Mukamagwiritsa ntchito mankhwala kumbuyo zamatsenga ngakhale opaleshoni ya msana milandu ya postoperative yolowera catheters neuroaxial hematomaskumayambitsa matenda amitsempha yamavutidwe osiyanasiyana, kuphatikizapo osasintha.

Supombocytopenia ndi vein prophylaxis odwala omwe ali ndi opaleshoni, chithandizo, komanso kuwonjezeka kwa gawo la ST, zinachitika 1-1% ya milandu ndipo mu 0.1-1% ya milandu ndi thrombosis Mitsempha mwa odwala omwe akupita pabedi ndikupatsidwa chithandizo myocardial infaration ndi.

Pambuyo pa kukhazikitsidwa kwa Clexane pansi pa khungu, mawonekedwe a hematomas pamalo opangira jekeseni. Mu 0.001% ya milandu, yapafupi necrosis khungu.

Kawirikawiri, khungu komanso kachitidwe ka zinthu, kuphatikiza.

Kukula kwakanthawi kochepa kwa chiwonetsero cha chiwindi kukufotokozedwanso.

Malangizo ogwiritsira ntchito Clexane

Malangizo ogwiritsira ntchito Clexane akuti mankhwalawa amaperekedwa mosamala kwambiri mu supine wodwala.

Momwe mungasinthire Clexane?

Mankhwalawa amayenera kuperekedwa kumanzere kumanzere kumanja. Kuti mugwiritse ntchito jakisoni, ndikofunikira kupanga mankhwalawa monga kutsegula syringe, ndikuwonetsa singano ndikuyika ndikuwonekera molondola, pakhungu lomwe linaphatikizidwa kale ndi chala chachikulu. Mimbayo imamasulidwa pambuyo pa jakisoni. Sitikulimbikitsidwa kupaka jakisoni jekeseni.

Vidiyo momwe mungasankhire Clexane:

Mankhwala saloledwa kuperekedwa intramuscularly.

Chiyankhulo. 2 jakisoni patsiku ndikuwonetsedwa kwa maola 12. Mlingo wa makonzedwe amodzi uyenera kukhala wa 100-anti-XA IU pa kilogalamu ya thupi.

Odwala omwe ali ndi chiopsezo chodziwika amafuna gawo la 20 mg kamodzi patsiku. Jakisoni woyamba ndi maola awiri asanafike opaleshoni.

Odwala omwe ali pachiwopsezo chachikulu cha kubadwa thrombosis tikulimbikitsidwa kupereka 40 mg ya Clexane kamodzi patsiku (oyamba kukhazikitsa maola 12 asanafike opaleshoni), kapena 30 mg ya mankhwalawa kawiri pa tsiku (oyamba kukhazikitsa pambuyo pa maola 13-24 pambuyo pa opaleshoni). Nthawi yayitali ya mankhwala ndi sabata kapena masiku 10. Ngati ndi kotheka, chithandizo chitha kupitilizidwa ngakhale kuti chiwopsezo cha thrombosis.

Chithandizo. Mankhwalawa amatumizidwa pa mlingo wa 1.5 mg pa kilogalamu yakulemera thupi kamodzi patsiku. Njira ya mankhwala nthawi zambiri imatenga masiku 10.

Kupewa thrombosis ndi embolism Mitsempha odwala wodwala pakama chifukwa cha matenda owopsa. Mlingo wofunikira wa mankhwalawa ndi 40 mg 1 nthawi patsiku (masiku 6-14).

Bongo

Kugwiritsa ntchito bongo mopitirira muyeso kungayambitse kwambiri hemorrhagic zovuta. Ndi kukamwa kwamlomo, kuyamwa kwa mankhwalawo mu kayendedwe kazinthu sikungatheke.

Kuwongolera pang'onopang'ono kumawonetsedwa ngati othandizira. protamine sulfate kudzera m'mitsempha. Mg imodzi ya protamine imasokoneza mg umodzi wa enoxaparin. Ngati maola opitilira 12 adutsa kuchokera pa kuyamba kwa bongo, ndiye kuti mawu oyamba protamine sulfate osafunikira.

Malangizo apadera

Mukamagwiritsa ntchito mankhwalawa kuti mupewe chizolowezi chowonjezereka cha magazi sichinapezeke. Mukamagwiritsa ntchito Clexane pochiritsa, pamakhala ngozi yotaya magazi kwa okalamba. Zikatero, kuyang'anira wodwalayo ndikofunikira.

Clexane sizimakhudza kuyendetsa.

Ma analogi a Kleksan

Kufanana kwa code ya ATX Level 4:

Ma analogi a Kleksan omwe ali ndi chinthu chofanana: Clexane 300, Novoparin, Enoxarin.

Zomwe zili bwino: Clexane kapena Fraxiparin?

Nthawi zambiri ndimawafunsa odwala funso lokhudza mphamvu yofanizira yamankhwala. ndi Clexane ali m'gulu lomwelo ndipo ndi fanizo. Palibe maphunziro omwe adatsimikizira kudalirika kwa mankhwala amodzi kuposa ena. Chifukwa chake, kusankha pakati pa mankhwalawa kuyenera kuchitika ndi adotolo pamaziko a chithunzi cha matendawo, momwe wodwalayo alili ndi zomwe akumana nazo.

Wochita kugawidwa mwa anthu ochepera zaka 18.

Zizindikiro ndi contraindication

Mwambiri, madokotala amapereka Flexan kapena Fraxiparin. Mankhwalawa ndi ofanana, kusiyana pakati pa Fraxiparin ndi Clexane pam kuchuluka kwa yogwira mankhwala limodzi. Clexane ndi theka wamphamvu monga Fraxiparin.

Kupatula apo, monga mukudziwa, magazi a mayi wapakati ndi wothinitsidwa kwambiri, kuchenjeza thupi kuti lisataye magazi ambiri pakubala. Koma ndi IVF, zizindikiritso pamwamba pazomwe sizili zovomerezeka, chifukwa cha izi, kusintha maselo ndikotheka.

Clexane ndi Fraxiparin amaperekedwa kwa amayi ambiri oyembekezera, koma si onse amene amadziwa chifukwa chake amapatsidwa jakisoni. Mankhwala onse awiriwa amathandiza kupewa magazi kuundana.

Chifukwa chiyani Kleksanpri IVF adalembedwa:

1. pakuchepa magazi,
2. thrombosis prophylaxis,
3. popewa masinthidwe amaselo chifukwa cha kuchitidwa opaleshoni pafupipafupi m'thupi,
4. mubwezeretse magazi moyenera kwa mwana wosabadwa.

Clexane mu IVF athandizira kuthana ndi mavuto amwazi. Ndikofunikira, musanayambe kugwiritsa ntchito mankhwalawa, ndibwino kukaonana ndi a hematologist, chifukwa thupi la mzimayiyu silingochira, komanso amavutika ndi mankhwalawa.

• matupi awo sagwirizana ndi heparin ndi zotumphukira zake,
• pali chiopsezo chochotsa mimbayo,
• Pali mbiri ya matenda omwe amatsatana ndi kukhetsa magazi.

Ndikofunika kudziwa kuti mankhwalawa sangathe kugwiritsidwa ntchito limodzi ndi acetylsalicylic acid ndi mankhwala omwe amapezeka.

Kuti mukwaniritse zotsatira zabwino kuchokera ku majakisoni, muyenera kutsatira malingaliro pazogwiritsidwa ntchito.

Kodi chabwino kuposa hemapaxan kapena fraxiparin ndi chiani? Ngakhale ali m'gulu la anticoagulants, zomwe zimagwira ntchito ndizosiyana kwa iwo, ndipo safunikira kufananizidwa.

Kuti mukwaniritse kwambiri, muyenera kupanga jakisoni moyenera.

• gona kumbuyo kwako
• Osamasula mpweya wa tambala wawo,
• Kuthira m'mimba malo opakidwa jakisoni wam'mimba,
• kupukuta khungu la m'mimba,
• Mankhwala ayenera kuperekedwa
• vomerezani kutulutsa khungu pambuyo pakubayidwa,
• osaponda malo a jakisoni,
• Lowani m'magawo osiyanasiyana pamimba.

Mankhwalawa ali mu ma syringe omwe amatayidwa kale, amakhala osabala.

Elena Volkova, Mwamuna, wazaka 42

Ndili kale ndi matenda a thrombophlebitis a m'munsi malembedwe kwa zaka 14, zowonongeka kwamitsempha. Zovuta mu mawonekedwe a trophic zilonda zam'munsi mwendo ndi ng'ombe. Ndimamwa mapiritsi a warfarin 2 kawiri pa tsiku. pafupifupi sabata limodzi, izi zisanachitike, kwa milungu ina iwiri, ndinamwa piritsi limodzi 2 kawiri pa tsiku.Makonzedwe aposachedwa a MNO1.14, IPT 84. M'mbuyomu, heparin wotsika kwambiri adapangidwira mumzinda wina, koma madokotala mumzinda wawo sanamvebe kuti mankhwalawa amagwiritsidwa ntchito. Ndikufuna kudziwa momwe mungawerengere mlingo wake komanso mankhwala omwe ali othandiza kwambiri. Kulemera kwanga ndi 105-110 kg. Kukonzekera kwa Clexane kapena fraxiparin. Mwina china ndichotheka. Ndangopeza izi. M'malo mwake, mutha kuyitanitsa mu mankhwala ngati amenewo. KLEKSAN INJECTION SOLUTION 8000 ANTI-HA ME / 0.8 ML. SYRINGES No. 10 FRAXIPARINE SOLUTION ПК К 9500 ANTI-HA ME / ML 0.8 ML. SYRINGES No. 10

Masana abwino Munazitenga zopanda kanthu, chifukwa muyenera kukhala ndi zikwangwani za INR za 2-3, apo ayi sizothandiza komanso zopanda tanthauzo. Mutha kuyimitsa ndi Pradax kapena (! Amatengedwa muyezo ndipo safuna kuwunika ma labotoreti) Ponena za clexane ndi fraxiparin, siabwino pamayendedwe oyendetsa. Musaiwale za jersey yapamwamba yapamwamba kwambiri pamavuto anu. Mwaulemu, dokotala wa Vascular Evgeny A. Goncharov

Kufunsidwa kwa phlebologist pamutu wakuti "Ndili ndi thrombophlebitis ndikufuna jekeseni wa clexane kapena fraxiparin" amangoperekedwa chifukwa chokhacho. Kutsatira malangizowo, chonde pitani kwa dokotala, kuphatikizapo kuti mupeze zotsutsana.

Dokotala, dokotala wa opaleshoni ya mtima (phlebologist), dokotala wamkulu wa opaleshoni, dokotala wozindikira za ma ultrasound.

Membala wa Russian Society of Angiologists ndi Vascular Surgeons, membala wa European Society of Vascular Surgeons, membala wa International Society of Lymphologists (ISL)

• VGMA iwo. N.N. Burdenko yemwe amagwira ntchito zamankhwala
• Zotsatira zamankhwala ku MMA dzina lake I.M.Sechenov, "opaleshoni" yapadera
• Zokhalapo zamankhwala ku NMHTS iwo. N.I. Pirogov, wamkulu mu opaleshoni yamtima,
• Professional retraining mu apadera "Ultrasound Diagnostics"

Gawo la ntchito: mitundu yonse ya opaleshoni ndi minyewa yodwala matenda am'mitsempha ndi mitsempha: atherosulinosis obliterans am'munsi miyendo ndi zotupa za ischemia ndi matenda ashuga, kupindika kwamitsempha yam'mimba komanso obadwa nawo am'mitsempha yamagazi, aneurysm yam'mimba komanso yam'mimba. , Matenda a Raynaud ndi matenda, mitsempha ya varicose yam'munsi, thrombosis ndi thrombophlebitis ya kumtunda ndi miyendo, miyendo ya m'mimba, elmphedema (elephantiasis), zilonda zam'mimba, varicose mitsempha yaing'ono ya pelvis (pelvic venous congestion syndrome), ndi zina, njira za endolymphatic zochizira matenda.

Sikuti mayi aliyense panthawi yoyembekezera amayenera kumwa mankhwala omwe amachepetsa magazi. Ngati izi zikufunika, madokotala amakonda Clexane. Komabe, mankhwalawa ali ndi zotsutsana zina ndipo amatha kuyambitsa mavuto.

Ndemanga za Odwala za Fraxiparin ndi Clexane

Natya, wazaka 56, Kursk: "Fraxiparin adamulamula asanagwidwe ntchito yolumikizana mafupa a bondo. Monga momwe dokotala amafotokozera, izi zimathandiza kupewa kutsekeka kwamitsempha yakuya pambuyo pakuchita opareshoni. "Kuyambitsa anticoagulant sikunakhudze opaleshoniyo. Mankhwalawa sanadzetse zotsatirapo zilizonse."

Fraxiparin kapena Clexane: ndibwino kuti musankhe mukakhala ndi pakati

Fraxiparin amatanthauza mankhwala omwe ali m'gulu la anticoagulant ndipo amawonetsa antithrombotic. Mankhwala amasintha magazi, amatulutsa cholesterol. The yogwira pophika mankhwala ndi nadroparin Ca, ndi ochepa maselo kulemera heparin, analandira chifukwa depolymerization a heparin.

Mphamvu ya antithrombotic imawonetsedwa chifukwa cha kutsegula kwa fibrinolysis pochotsa plasminogen activator mwachindunji ku maselo a endothelial komanso kukondweretsa kwina kwa minyewa ya minyewa yoteteza minyewa yokha. PM amadziwika ndi kutalika kwa nthawi ya antithrombotic.

Ambiri ali ndi chidwi ndi kusiyana pakati pa Clexane ndi Fraxiparin, chifukwa mankhwalawa ali ndi zofanana. Fraxiparin, mosiyana ndi Clexane, ili ndi enoxaparin Na. Kuphatikiza pa kanthu ka antithrombotic, palibe chomwe chimakhudzana ndi kulumikizana kwa fibrinogen mwachindunji ndi mapulateleti ophatikizika, komanso njira yophatikizira maselo am'magazi.

Mukasankhidwa

Ndikofunikira kumangodula Fraksiparin ndi Kleksan muzochitika ngati mkaziyo ali ndi vuto la thrombosis kapena mayi wam'tsogolo akadakhala ndi valavu yamtima. Tikulimbikitsanso kuti mankhwala omwe ali ndi mankhwalawa a thrombophilia, mapangidwe amitsempha yamagazi m'mitsempha yayikulu, ndi ischemia, komanso pomwe mtima kapena kupuma kwamphamvu kwapezeka.

Nthawi zambiri, madokotala amalimbikitsa Clexane kuti agwiritsidwe ntchito kupewa, amasonyezedwa kuti agwiritsidwe ntchito mu nyengo yachiwiri ya mimba. Ngati mankhwalawa sioyenera mkazi, Fraxiparin angagwiritsidwe ntchito.

Komanso, mankhwalawa amatha kuikidwa ndi protocol yoyamba ya IVF, kugwiritsa ntchito mankhwalawa kuyenera kuchitika motsogozedwa ndi akatswiri.

Zolemba ntchito

Mankhwala onse awiriwa amapangidwira kukonzekera kwa sc; ma jakisoni a mu mnofu saloledwa.

Kodi jakisoni

Ndikulimbikitsidwa kupaka jakisoni mkaziyo atagona. Malowo a jekeseni ayenera kusinthidwa (mbali kumanzere ndi kumanja kwa anterolateral kapena posterolateral dera lam'mimba). Pambuyo pogwira khola la pakhungu pakati pa chala chakumaso ndi chala, singano imayikidwa molunjika. Kusokoneza gawo lamankhwala osokoneza bongo sikuyenera kutero. Kutalika kwa mankhwalawa nthawi zambiri kumakhala masiku 7-10. Pambuyo pa izi, ndikulimbikitsidwa kuti mupereke magazi kuti awunikiridwe kuti awonetsetse kuti ziwerengero zonse za mapuloteni ndizabwinobwino. Ndikofunika kusunga kalendala yosungiramo mankhwala osokoneza bongo sabata sabata.

Mlingo wa Clexane kapena Fraxiparin umatsimikiziridwa payekhapayekha. Popewa thrombosis, 40 mg ya Clexane amalembedwa kamodzi pa tsiku kwa masabata 1-2. Ndi mitsempha yakuya, 1.5 mg ya mankhwalawa pa 1 makilogalamu a kulemera kwa 1 p. tsiku lonse kapena 1 mg kawiri pa tsiku. Ngati ma ampoules omwe ali ndi mankhwalawa akadakhalabe ndi pakati, atha kugwiritsidwa ntchito ngati pakufunika m'tsogolo.

Mwachizolowezi, mapaketi a Fraxiparin ndi okwanira pamapeto a mankhwalawa, osachepera mlingo wa mankhwalawa ndi 0,3 ml, kuyambitsa kwa mankhwala kumachitika kamodzi patsiku. Ngati katswiri wazakudya zamtundu wa mankhwalawa atalamula kugwiritsa ntchito mankhwalawa malinga ndi chiwembu china, kulemera kwa thupi la wodwalayo komanso msinkhu wake wophunzitsidwa bwino zimakumbukiridwa.

Fraxiparin kapena: zomwe ndi bwino kusankha pakati pa mimba

Fraxiparin amatanthauza mankhwala omwe ali m'gulu la anticoagulant ndipo amawonetsa antithrombotic. Mankhwala amasintha magazi, amatulutsa cholesterol. The yogwira pophika mankhwala ndi nadroparin Ca, ndi ochepa maselo kulemera heparin, analandira chifukwa depolymerization a heparin.

Mphamvu ya antithrombotic imawonetsedwa chifukwa cha kutsegula kwa fibrinolysis pochotsa plasminogen activator mwachindunji ku maselo a endothelial komanso kukondweretsa kwina kwa minyewa ya minyewa yoteteza minyewa yokha. PM amadziwika ndi kutalika kwa nthawi ya antithrombotic.

Ambiri ali ndi chidwi ndi kusiyana pakati pa Clexane ndi Fraxiparin, chifukwa mankhwalawa ali ndi zofanana. Fraxiparin, mosiyana ndi Clexane, ili ndi enoxaparin Na. Kuphatikiza pa kanthu ka antithrombotic, palibe chomwe chimakhudzana ndi kulumikizana kwa fibrinogen mwachindunji ndi mapulateleti ophatikizika, komanso njira yophatikizira maselo am'magazi.

Kufanana kwa nyimbo za Fraxiparin ndi Clexane

Fraxiparin ndi anticoagulant wokhala ndi katundu wa antithrombotic. Amakhazikitsa microcirculation ndipo amatulutsa magazi m'thupi. Chithandizo chophatikizika cha mankhwalawa ndi calcium calcium.

Ntchito ya antithrombotic yogwira ntchito imakhala ndi mphamvu yotentha pa hemostasis. Mwansanga zimakhala ndi zotsatira zosatha.

Clexane ndi heparin wochepa kwambiri wamankhwala, komanso anticoagulant. Zomwe zimagwiritsidwa ntchito ndi enoxaparin sodium, zokhudzana ndi heparins. Mphamvu ya mankhwalawa imawonetsedwa ndikuwonetsedwa kwa antithrombin III, chifukwa chomwe zoletsa za zinthu IIa ndi Xa zimalepheretsedwera.

Mankhwalawa ali ndi antithrombotic nthawi yayitali, omwe alibe vuto pakulimbana kwa fibrinogen ndi mapulateleti.

• kupewa matenda a thromboembolism pambuyo pa opaleshoni,
• mankhwalawa thromboembolism, angina pectoris, varicose mitsempha, mtima.

• kupewa matenda a venous thrombosis,
• mankhwalawa angina pectoris, thrombosis, mtima.

Fraxiparin imalowetsedwa m'mitsempha komanso mozungulira. Mankhwalawa kumatha sabata, mlingo wa tsiku ndi tsiku ndi 0,3 ml. Mlingo woyambayo umaperekedwa kwa maola awiri musanachite opareshoni. Mu opaleshoni ya mafupa, mlingo woyambirira wa mankhwalawa umaperekedwa maola 12 opareshoni isanathe maola 12 pambuyo pa njirayi. Njira ya chithandizo ndi masiku 10.

Clexane amagwiritsidwa ntchito ngati jekeseni wofikira. Mankhwala sangathe kutumikiridwa intramuscularly. M'matumbo ntchito, mankhwala kutumikiridwa mu 20-25 ml ya tsiku. Jakisoni woyamba amachitika maola awiri isanachitike ndondomeko. Pakulimbikitsa kwa mafupa, mlingo wa 40 mg patsiku umagwiritsidwa ntchito. Mlingo woyamba umaperekedwa maola 12 musanachite opareshoni. Njira ya mankhwala kumatenga masiku 7-10.

Fraxiparin sangaphatikizidwe ndi njira iliyonse. Zotsatira pa Fraxiparin:

• Hypersensitivity mankhwala
• magazi
• zilonda zam'mimba kapena zilonda zam'mimba,
• endocarditis.

Mankhwalawa amayambitsa thrombocytopenia.

Zotsatira pa Clexane:

• Hypersensitivity mankhwala
• magazi
• mimba
• kupezeka kwa valavu wamtima,
• wosakwana zaka 18
• chilonda
• ischemic stroke
• kubadwa kwaposachedwa
• endocarditis
• matenda ashuga
• pericarditis
• chiwindi ndi impso ntchito.

Fraxiparin imatha kuyambitsa zotsatirazi:

• thupi lawo siligwirizana
• magazi
• chiwindi ntchito,
• hematomas pa jekeseni malo,
• thrombocytopenia
• Hyperkalemia

Mankhwalawa ndi Clexane, zotsatira zoyipa zingachitike:

• magazi
• kukha m'mimba,
• kukokana magazi
• hematomas
• zovuta zamitsempha
• ziwalo
• paresis
• thrombocytopenia
• thupi lawo siligwirizana.

Ndi chitukuko cha magazi, ndikofunikira kusiya mankhwala ndi mankhwala othandizira.

Kodi pali kusiyana kotani pakati pa Fraxiparin ndi Clexane

Mankhwalawa ali ofanana, kusiyana pakati pa Fraxiparin ndi Clexane kumangokhala mu kuchuluka kwa zinthu zomwe zimagwiritsidwa ntchito pa mlingo umodzi. Clexane ndi theka wamphamvu monga Fraxiparin.

Clexane amagwiritsidwa ntchito popanga zinthu zosafunikira:

• pakuchepa magazi,
• thrombosis prophylaxis,
• pofuna kupewa masinthidwe amaselo,
• mubwezeretse magazi moyenera kwa mwana wosabadwa.

Mtengo wa mankhwalawa Clexane m'masitolo:

1. Syringes 40 mg, 0,4 ml, 10 ma PC. (France), mtengo - ma ruble 2760.
2. Syringes 60 mg, 0,6 ml, 2 ma PC. (France), mtengo - ma ruble 713.
3. Syringes 20 mg, 0,2 ml, ma PC 10. (France), mtengo - 1785 rubles.

Mtengo wa mankhwala a Fraxiparin pama pharmacies:

1. Syringes 2850 IU 0.3 ml 10 ma PC. (Ireland), mtengo - ma ruble a 1950.
2. Syringes 5700 IU 0.6 ml 10 ma PC. (Ireland), mtengo - 3409 rubles.
3. Syringes 7600 IU 0.8 ml 10 ma PC. (Ireland), mtengo - 4640 rubles.
4. Syringes 3800 IU 0.4 ml 10 ma PC. (Ireland), mtengo - ruble 2934.

Madokotala amakhulupirira kuti kuyankha funso lomwe kuli bwino ndikovuta. Kwa munthu aliyense, dokotala amasankha mankhwalawo payekha. Fraxiparin ili ndi zotsutsana zochepa ndipo imayambitsa zovuta zochepa. Clexane imatha kuyambitsa zotsatira zoyipa zingapo zoyipa.

Mtengo wa Fraxiparin ndi wotsika mtengo. Pogwira ntchito, mankhwalawa onse amakhala ndi mitengo yambiri.

Dokotala akapereka imodzi mwa mankhwalawa, ayenera kufufuza kaye wodwalayo ndikuwonetsetsa ngati wodwalayo ali ndi matenda omwe mankhwalawo amapangidwira.

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Atsikana akufunika upangiri, ndibwino kuti Kleksan kapena Fraksiparin?
Adotolo adandiuza Fraxiparin, koma ndidamva kuti anali ndi zotsatira zoyipa kuchokera kwa Clexane.

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Kleksan Och amalankhula mopweteka! Ndipo Fraxiparin sichoncho

Ndipo kotero onse ndiabwino

Doctor Kleksan adandiuza. Kusoka kulibe vuto kwenikweni (ngakhale ndili ndi zowawa zowawa ndipo ndikuopa kuwawa). Sanamve konse

Ngati nditenga heparin kuti ndichepetse magazi

Anandisankha Clexane

- @ marika7051 heparin nthawi yapakati? imatha kukhala yaubongo kapena fungo

Ndikumenya Kleksan tsopano, zimandipweteka!

Mimba zonse ziwiri zidasokonekera

Panalibe zovuta zilizonse, kodi anakuthandizani? @ 1978koty

Sindikudziwa kuti ndikabisala bwanji его Atsikana ndiuzeni chonde

Anandisankhira heparin analogue ya fraseparin mu moniage

Ndipo mapulateleti ndi abwinobwino

- @ marika7051 Ndimatenga woyamba. atagona mumzinda woyamba, mwatsatanetsatane, pomwe adandiuza kuti heparin anali ndi zotsatira zoyipa, sanavulazidwe konse. ndipo ndi angati omwe sanagonepo zipatala zokhazokha kapena zanzeru zokha

- @ elena51577 ttt, ayi, atsikana onse awiri akuchita bwino. Ndidayang'ana mu YouTube momwe ndikubaya bwino. poyamba zinali zowopsa, kenako monga momwe zimayembekezera popanda mantha

Dokotala adatiuza Kleksan otetezeka kwambiri

Prick dera la umbilical subcutaneally. Ndimakonda tebulo la odwala: pamimba, yosungirako idatenga mfundo ndi msondodzi. Amati sizivulaza, sizabwino basi. Pakhoza kukhala mikwingwirima kuzungulira Mchombo.

Dotolo adati mungathe ndi Kleksan.

Ine poyamba a fxiparin 0,3 kwa nthawi yayitali, kenako ziwonetsero zinafika pofufuza, sindikudziwa za izi kapena china chilichonse, koma adandisamutsira ku clexane 0,4, koma ndilibe chilichonse, tsopano ndachuluka mpaka 0,6 , tiyang'ana. Ndikutanthauza, muyenera kuyesa ndikusankha zomwe zikugwira ntchito. Ndipo sindinakhalepo ndi zotsatila pamapulogalamu)

Kolya fraksiparin onse mimba, palibe mavuto! Adotolo akuti ndi omwewo! Koma clexane alibe mulingo wa 0,3, ndipo ndikungofunikira 😊 ndichifukwa chake adayilamula!

Mu 1b, fraxeparin adabayidwa. kunalibe zoyipa. About Kleksan ndiye sanamve.

Ali ndi njira ina. Clexane, mwachitsanzo, samandithandiza, d-dimer yokha idakula. sizinawakhudze konse ndi fungo laxxiparin

- @polimishik, yemweyo pazifukwa zina, d-dimer ikukula kokha. Muli kale kuchuluka kwake. 0.6 + 0,6 patsiku

Sinthani kukhala fraxiparin, mwina clexane sikuyenera inu. 0.6 + 0,6 ndizambiri!

Sungani macheke kuchokera ku Kleksan, ndiye kuti mutha kubweza 13% ya ndalama zomwe mudalipira. Ndidalipira mimba yanga yonse ndikubweza ruble 8,000. Mutha kuwerenga zambiri mu PM kapena gulu langa https://m.vk.com/vernindfl2015

- @ persefona-85, koma munasintha bwanji kuchokera pamankhwala ena kupita pamzake? Mawa lake adasumanso wina? Kapena kodi adapuma tsiku limodzi kapena awiri?

- @marmelade nthawi yomweyo tsiku lotsatira adabera wina.

- @ persefona-85, zikomo kwambiri! ☺️ Ndiyenera kupita mawa) ndipo palibe amene akuyankha funso langa mu mtsinje. kuda nkhawa

- @marmelade, wokondwa kuthandiza))

Ndi kukhudzika kowonjezereka kwa magazi, ma anticoagulants amagwiritsidwa ntchito popewa magazi. Mankhwalawa ali ndi nyimbo zosiyanasiyana komanso njira zake. Odwala nthawi zambiri amafunsa kuti asankhe chiyani, Fraxiparin kapena Clexane. Kuwunika kwa ma anticoagulants awiri kungathandize kumvetsetsa kuti ndi mankhwala ati omwe ali oyenera panthawi inayake.

Njira yogwiritsira ntchito

Mankhwala amangokhala osokoneza bongo komanso osokoneza bongo:

1. opaleshoni yayikulu . Ndikulimbikitsidwa kugwiritsa ntchito mankhwalawa kwa masiku osachepera asanu ndi awiri pa mlingo wa mamililita 0,3. Mlingo woyamba umaperekedwa kwa odwala maola awiri kapena anayi asanafike,
2. opaleshoni yamatsenga . Mlingo woyamba wa Fraxiparin umaperekedwa kwa odwala maola khumi ndi awiri asanachitidwe opaleshoni, komanso pambuyo pa nthawi yomweyo. Mankhwala tikulimbikitsidwa kugwiritsa ntchito mkati mwa masiku khumi.

Mankhwala Clexane amagwiritsidwa ntchito pokhapokha pochita mankhwalawa, komabe muyenera kudziwa kuti mankhwalawa saloledwa kuperekedwa kudzera mwa mankhwalawa:

• pamimba . Amagwiritsidwa ntchito pa Mlingo wa 20 mamililita kamodzi patsiku kamodzi. Mlingo woyambirira musanachitike opaleshoni imaperekedwa mu maola awiri,
• pa mafupa . Mlingo wa ma milligram 40 amagwiritsidwa ntchito kamodzi patsiku kamodzi. Poyamba, mankhwalawa amaperekedwa maola 12 asana opaleshoni. Komabe, palinso njira ina yothandizira, ndipo ndi mamililita 30 kawiri pa tsiku, ndipo mlingo woyambayo umaperekedwa kwa maola 12-24 atachitidwa opaleshoni.

Njira yamankhwala yothandizira ndi chida ichi kuyambira sabata limodzi mpaka masiku 10, pomwe amatha kupitilizidwa mpaka nthawi ina, pomwe pali chiopsezo cha thrombosis. Nthawi zambiri amawonjezera osaposa masabata asanu.

Ndikofunikira kudziwa kuti Fraxiparin sagwiritsidwa ntchito intramuscularly, ndipo sizoyenera kuti zisakanikirane ndi mankhwala ena.

Zotsatira zoyipa

Pa mankhwala a Fraxiparin, zotsatirazi zoyipa zimachitika:

• thupi lawo siligwirizana
• magazi
• kuchuluka kwa michere ya chiwindi,
• hematomas yaying'ono pa jekeseni,
• zotupa zowonda pamankhwala jakisoni,
• thrombocytopenia
• eosinophilia
• Hyperkalemia

Pa mankhwala ndi Clexane, zotsatirazi zoyipa zimachitika:

• magazi
• hemorrhagic syndrome
• kukula kwa hemorrhage m'malo obwezeretsanso,
• kukula kwa hemorrhage mu cranial patsekeke,
• zotsatira zakupha
• Kukula kwa hematoma
• kukula kwa matenda amitsempha,
• ziwalo
• paresis
• thrombocytopenia
• thupi siligwirizana pa jakisoni malo,
• kuchuluka kwa transaminases.

Ndi magazi, ndikofunikira kusiya kugwiritsa ntchito Clexane.

Ngati khungu likupweteka komanso kufupika kwa khungu pakhungu, ndikofunikira kuti musiye kugwiritsa ntchito ndi kufunsa dokotala.

Kodi dokotala angamulezere Clexane mpaka liti?

Lingaliro la kuthekera kophatikizidwa mu regimen yothandizira a Clexane limapangidwa ndi adokotala okha. M'miyezi itatu yoyambirira ya mimba, madokotala amayesetsa kuti asapereke jakisoni kwa amayi oyembekezera. Izi ndichifukwa choti palibe data pazomwe zimagwira ntchito pa mluza. M'masiku oyambilira, ndikofunikira kwambiri kuchepetsa kuopsa kwa matenda a mwana, chifukwa ndi nthawi imeneyi pomwe ziwalo zonse za mwana zimapangidwa.

Malinga ndi malangizo, mankhwalawa ndi osayenera kwa amayi apakati. Komabe, pochita, madokotala nthawi zambiri amalemba kuti ichitike kuyambira wachiwiri. Koma chithandizo chikuyang'aniridwa ndi dokotala yemwe amayang'anira bwino thanzi la mayi, amaphunzira kusintha kwa ziwerengero zamagazi.

Chiberekero chokula sichimangolekerera ziwalo zamkati mwa mkazi, komanso chimachulukitsa kukakamiza kwa mitsempha. Zotsatira zake, pamakhala kutupa m'mitsempha yamitsempha yamagazi ndikupanga kwa magazi. Clexane anapangidwa kuti ateteze thrombosis m'chiuno ndi m'munsi.

Momwe mungapereke jakisoni

Njira zoyendetsera Clexane ndizosiyana ndi nthawi zonse. Chowonadi ndi chakuti mankhwalawo saloledwa kupaka jekeseni kapena m'mitsempha. Malinga ndi malangizo, jakisoni amapangidwa mwakuya pansi pa khungu kumanzere ndipo kumanzere kwamanja. Mlingo wokhazikitsidwa ndi adokotala okha, kutengera mayi omwe akuyembekezeredwa ndi machitidwe a munthu yemwe ali ndi pakati. Nthawi zambiri, amayi omwe akuyembekezera mwana amapatsidwa mlingo wa tsiku ndi tsiku, womwe ndi 0-0-0.4 ml ya yankho.

Malangizo a kukhazikitsidwa kwa khungu pansi pamimba

Kuti mulowetse mankhwalawo molondola m'thupi, muyenera kutsatira zotsatirazi.

Kuti zitheke, madokotala amakulangizani kuti muzichita njirayi mwachangu. Njira ya chithandizo imatsimikizidwanso ndi dokotala. Pafupifupi, ndi masiku 7-14.

Momwe mungasiyere mankhwalawa: lekani kwambiri kapena pang'onopang'ono

Kuchotsa kwa Clexane asanabadwe mwana kuli ndi mawonekedwe ake. Nthawi zina, amamukankha kwambiri (mwachitsanzo, kuwopseza kuti angatenge pang'onopang'ono komanso kutaya magazi). Koma nthawi zambiri, izi zimayenera kuchitika pang'onopang'ono moyang'aniridwa ndi dokotala, pang'onopang'ono kuchepetsa Mlingo ndikuwunika magazi pafupipafupi. Gawo lamasamba lisanachitike, kugwiritsa ntchito mankhwalawa nthawi zambiri kumayimiridwe tsiku limodzi lisanachitike, ndipo pambuyo pake ma jekeseni angapo amapangidwa kuti magazi asapangidwe.

Pazinthu zonse zovuta kuzimitsidwa kwa Kleksan auzeni katswiri.

Clexane pa mimba ndi mkaka wa m`mawere

Ndi zoletsedwa (kupatula pomwe phindu kwa mayi limakhala lalikulu kuposa chiopsezo kwa mwana wosabadwayo) kugwiritsa ntchito Clexane panthawi yapakati. Zotsatira zake zitha kukhala zosayembekezereka, chifukwa palibe chidziwitso chazomwe zimagwiritsidwa ntchito ndi Clexane panthawi yomwe ali ndi pakati pa nthawi yake.

Ngati mukufuna kugwiritsa ntchito Clexane, muyenera kusokoneza kuyamwitsa panthawi yamankhwala.

Mayi.life. Pulogalamu yamayi amakono

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Atsikana akufunika upangiri, ndibwino kuti Kleksan kapena Fraksiparin?
Adotolo adandiuza Fraxiparin, koma ndidamva kuti anali ndi zotsatira zoyipa kuchokera kwa Clexane.

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Kleksan Och amalankhula mopweteka! Ndipo Fraxiparin sichoncho

Ndipo kotero onse ndiabwino

Doctor Kleksan adandiuza. Kusoka kulibe vuto kwenikweni (ngakhale ndili ndi zowawa zowawa ndipo ndikuopa kuwawa). Sanamve konse

Ngati nditenga heparin kuti ndichepetse magazi

Anandisankha Clexane

- @ marika7051 heparin nthawi yapakati? imatha kukhala yaubongo kapena fungo

Ndikumenya Kleksan tsopano, zimandipweteka!

Mimba zonse ziwiri zidasokonekera

Panalibe zovuta zilizonse, kodi anakuthandizani? @ 1978koty

Sindikudziwa kuti ndikabisala bwanji его Atsikana ndiuzeni chonde

Anandisankhira heparin analogue ya fraseparin mu moniage

Ndipo mapulateleti ndi abwinobwino

- @ marika7051 Ndimatenga woyamba. atagona mumzinda woyamba, mwatsatanetsatane, pomwe adandiuza kuti heparin anali ndi zotsatira zoyipa, sanavulazidwe konse. ndipo ndi angati omwe sanagonepo zipatala zokhazokha kapena zanzeru zokha

- @ elena51577 ttt, ayi, atsikana onse awiri akuchita bwino. Ndidayang'ana mu YouTube momwe ndikubaya bwino. poyamba zinali zowopsa, kenako monga momwe zimayembekezera popanda mantha

Dokotala adatiuza Kleksan otetezeka kwambiri

Prick dera la umbilical subcutaneally. Ndimakonda tebulo la odwala: pamimba, yosungirako idatenga mfundo ndi msondodzi. Amati sizivulaza, sizabwino basi. Pakhoza kukhala mikwingwirima kuzungulira Mchombo.

Dotolo adati mungathe ndi Kleksan.

Ine poyamba a fxiparin 0,3 kwa nthawi yayitali, kenako ziwonetsero zinafika pofufuza, sindikudziwa za izi kapena china chilichonse, koma adandisamutsira ku clexane 0,4, koma ndilibe chilichonse, tsopano ndachuluka mpaka 0,6 , tiyang'ana. Ndikutanthauza, muyenera kuyesa ndikusankha zomwe zikugwira ntchito. Ndipo sindinakhalepo ndi zotsatila pamapulogalamu)

Kolya fraksiparin onse mimba, palibe mavuto! Adotolo akuti ndi omwewo! Koma clexane alibe mulingo wa 0,3, ndipo ndikungofunikira 😊 ndichifukwa chake adayilamula!

Mu 1b, fraxeparin adabayidwa. kunalibe zoyipa. About Kleksan ndiye sanamve.

Ali ndi njira ina. Clexane, mwachitsanzo, samandithandiza, d-dimer yokha idakula. sizinawakhudze konse ndi fungo laxxiparin

- @polimishik, yemweyo pazifukwa zina, d-dimer ikukula kokha. Muli kale kuchuluka kwake. 0.6 + 0,6 patsiku

Sinthani kukhala fraxiparin, mwina clexane sikuyenera inu. 0.6 + 0,6 ndizambiri!

Sungani macheke kuchokera ku Kleksan, ndiye kuti mutha kubweza 13% ya ndalama zomwe mudalipira. Ndidalipira mimba yanga yonse ndikubweza ruble 8,000. Mutha kuwerenga zambiri mu PM kapena gulu langa https://m.vk.com/vernindfl2015

- @ persefona-85, koma munasintha bwanji kuchokera pamankhwala ena kupita pamzake? Mawa lake adasumanso wina? Kapena kodi adapuma tsiku limodzi kapena awiri?

- @marmelade nthawi yomweyo tsiku lotsatira adabera wina.

- @ persefona-85, zikomo kwambiri! ☺️ Ndiyenera kupita mawa) ndipo palibe amene akuyankha funso langa mu mtsinje. kuda nkhawa

- @marmelade, wokondwa kuthandiza))

Nthawi zina zimachitika kuti nkovuta kwambiri kuti okwatirana akhale ndi mwana. Pachifukwa ichi, amakakamizidwa kugwiritsa ntchito njira zina zam'mimba. Koma pankhaniyi, ndikofunikira kuthandiza thupi la amayi ndi mankhwala, chifukwa IVF isanalandire chithandizo cha mahomoni. Popeza magazi a mayi wapakati amakula, izi zimakhala zowawa osati zake zokha, komanso kufalikira kwa magazi a mwana wosabadwayo. Chifukwa chake, adayikidwa anticoagulants. Koma zomwe zili bwino Kleksan kapena Fraksiparin - chidziwitso chotsatirachi chikuthandizira kumvetsetsa.

Mphamvu ndi chitetezo cha mankhwalawa Clexane

Clexane ali m'gulu la anticoagulants omwe amawongolera mwachindunji; amagwiritsidwa ntchito kukonza magawo a masinthidwe amwazi (kusintha kwamitsekedwe) wamagazi. Makampani opanga mankhwala amapanga othandizira mu mawonekedwe a zotayira zagalasi zotayidwa ndi mtundu wachikaso kapena wowoneka bwino wamadzimadzi osiyanasiyana.

Chofunikira chachikulu cha Clexane ndi enoxaparin sodium, ndipo madzi amagwira ntchito ngati chothandizira. The bioavailability wa mankhwala ndi subcutaneous makonzedwe ndi 100%. Izi zikutanthauza kuti mankhwalawa amamwa kwathunthu.

Clexane ndimagulu anthawi yomweyo olimbana ndi magazi

Chidacho chimayambitsa antithrombin III (puloteni inayake ya thupi), potero chimalepheretsa mapangidwe magazi. Chifukwa cha antithrombotic ya mankhwala, magazi amayamba kuchepa, mamvekedwe ake amakula.

Malangizowo alibe zambiri zomwe Kleksan amaletsedwa kugwiritsa ntchito panthawi yomwe ali ndi pakati. Komabe, zikuwonetsedwa kuti mankhwalawa amalembedwa pokhapokha pali zisonyezo zoyenera za izi zomwe zimakhazikitsidwa ndi hematologist kapena gynecologist.

Clexane akhazikitsidwa bwino muzochita zamankhwala, malingaliro a madokotala okhudza mankhwalawa ndi abwino. Komabe, pali malingaliro ena. Chowonadi ndi chakuti panthawi yoyembekezera, njira yopatsirana (kukhathamira kwa magazi, komwe kumalumikizidwa ndi kukonzekera kubala mwana) ndizomwe zimachitika. Chifukwa chake, nthawi zambiri, mayi woyembekezera sayenera kugwiritsa ntchito othandizira a thrombolytic.

Kwa amayi omwe ali ndi mtima wofuna kupindika, Clexane amalimbikitsidwa ngati prophylaxis limodzi ndi njira zina, popeza ali ndi mwayi wa 50% wamagazi (makamaka, mu 90% ya milandu, zovuta za thromboembolic zimayamba pambuyo pobala). Pogwiritsa ntchito mankhwalawa chifukwa cha prophylactic, panalibe njira yowonjezereka yowoneka ngati magazi.

Zizindikiro zazikulu za Clexane pa nthawi yapakati ndi:

• mitsempha yakuya,
• kukulitsa kwa hypercoagulable syndrome (kuchuluka kwa magazi)
• angina wosakhazikika,
• kulephera kwa mtima
• makonzedwe a thrombosis.

Kwa mayi woyembekezera, mankhwalawa amalembedwa kokha mu II ndi III trimesters. Sizinaphunziridwebe momwe mankhwalawa amakhudzira kukula kwa mluza, chifukwa chake, mu masabata 12 oyamba, pamene ziwalo ndi machitidwe a mwana zimayikidwa, sizinasankhidwe.

US Food and Drug Administration yasankha Clexane ngati Gulu B. Izi zikutanthauza kuti kuyesa kwanyama sikunawonetse mwana wosabadwa. Komabe, maphunziro okwanira ndi okwanira pa amayi apakati sanachitike. Chifukwa chake, adokotala amatha kukupatsirani mankhwala pokhapokha ngati pakufunikira kugwiritsidwa ntchito kwake.

Malangizo ogwiritsira ntchito mankhwalawa

Mlingo ndi kutalika kwa mankhwalawa zimatsimikizika malinga ndi zovuta za matendawa, msinkhu wa mayi wapakati komanso kulemera kwake. Mankhwalawa amatengedwa pokhapokha ngati adanenedwa ndi adokotala komanso kuyang'aniridwa mwamphamvu. Njira ya mankhwalawa imatha kukhala masiku 2 mpaka 10, ngati ndi kotheka, pitilizani.

Mankhwala Kleksan amamasulidwa kwathunthu ndi zotayidwa zochuluka ma syringes

Njira yoyambira

Jakisoni amaperekedwa pokhapokha m'mimba.

1. Asanachite izi, mayiyo amagona pabedi.
2. Jakisoni amapangidwa kumanzere kapena kumanja kwa navel.
3. Mu malo osankhidwa, khungu limasonkhanitsidwa mu khola ndipo syringe imayikidwa mmalo mosamalitsa mpaka kuzama konse.
4. Wothandizirayo atadziwitsidwa bwino, khungu limamasulidwa.

Tiyenera kukumbukira kuti ndizoletsedwa kutikita minofu ndikumanga jekeseni.

Amayi oyembekezera amatenga jakisoni wa Clexane kuchokera kwa anamwino odziwa ntchito pachipatala

Jekeseni ndizoletsedwa kulowa intramuscularly. Pamodzi ndi mankhwala Kleksan, adotolo, monga lamulo, amapereka malangizo a draantes kapena Dipyridamole (kusintha kayendedwe ka magazi, kusintha kwa magazi mosakhalitsa, komanso kuthana ndi fetal hypoxia.

Sikulimbikitsidwa kuti mwadzidzidzi musiye kudukiza. Madokotala amalangizira pang'onopang'ono kuchepetsa Mlingo wa mankhwalawa ndikusiya kupereka jakisoni pakadutsa masiku awiri asanabadwe (gawo la cesarean - patsiku). Izi zimachitika kuti pasakhale mavuto atatuluka magazi. Pambuyo pobereka, jakisoni amayambiridwanso pamlingo wochepera kupewa magazi.

Kukonda kwa mankhwala

Clexane ndi wa gulu la ma hematini otsika kwambiri olemera, motero palibe analogue yathunthu pamankhwala. Mankhwala onse amasiyana kulemera maselo, kapangidwe kake ndi zotsatira zake pa thupi la mayi wapakati.

Kusintha Clexane ndi mankhwala ena ndikotheka chifukwa cha zovuta kapena mawonekedwe ena osayenera.

Gome - Mankhwala osokoneza bongo pofuna kupewa thrombosis ovomerezeka ndi amayi apakati

Syringe imodzi imakhala, kutengera mtundu: 10000 anti-Ha ME, 2000 anti-Ha ME, 8000 anti-Ha ME, 4000 anti-Ha ME kapena 6000 anti-Ha ME enoxaparin sodium.

Kugwiritsa ntchito limodzi ndi mankhwala ena

Ndi zoletsedwa kugwiritsa ntchito Clexane pamodzi ndi mankhwala ena omwe amakhudza njira zopangira magazi, mwachitsanzo, ndi Curantil kapena Dipyridamole. Ndi magulu ena amankhwala, mwachitsanzo, mankhwala osapweteka a antiidal

Kodi ma fanizo ndi njira zina ziti zitha kusintha Clexane

Pali mankhwala ena omwe amachokera ku enoxaparin sodium pamsika wa pharmacological, chifukwa chake opanga mankhwalawa atha kubwezeretsa. Zofananira zonse za Xexan ndi:

Ngati, chifukwa cha chithandizo ndi Clexane, mzimayi akukumana ndi zovuta zosayenera kapena ali ndi zotsutsana chifukwa chogwiritsidwa ntchito, dokotala yemwe amapezekapo amasankha mankhwala ena. Zofanana zochizira zofanana ndi izi:

• Fraxiparin ndi chinthu chothandiza pothandiza kupewa matenda a magazi,
• Warfarin - imapezeka m'mapiritsi a buluu ndipo imagwiritsidwa ntchito panthawi yoyembekezera kwa mwana wachiwiri ndi wachitatu kokha,
• Fragmin - yankho la jakisoni lili ndi antithrombotic.

Chimbale: Fraxiparin, Warfarin, Gemapaxan ndi mankhwala ena omwe amagwiritsidwa ntchito pochiza thrombosis

Fragmin adalembedwa kuti azimayi apakati azitha kuchiza matenda a thrombosis
Warfarin ndi yoletsedwa mu trimester yoyamba ya mimba. Fraxiparin imapezeka ngati jakisoni.

Anfibra amapezeka mu milingo ingapo. Gemapaxan imagwiritsidwa ntchito kuceza magazi ndikulimbana ndi magazi.

Gome: Makhalidwe a mankhwala omwe angathe kuperekedwa kwa amayi apakati kuti asinthe Clexane

Mumlife - ntchito kwa amayi amakono

Tsitsani kwa iPhone, Android

Atsikana akufunika upangiri, ndibwino kuti Kleksan kapena Fraksiparin?
Adotolo adandiuza Fraxiparin, koma ndidamva kuti anali ndi zotsatira zoyipa kuchokera kwa Clexane.

Tsegulani pakugwiritsa ntchito

Polemba pulogalamuyi mutha kuyang'ana zithunzi zonse zalemba uyu, komanso ndemanga ndikuwerenga zolemba zina za wolemba

M'mayendedwe Mum Mum -
mwachangu komanso mosavuta

Ndemanga

Kleksan Och amalankhula mopweteka! Ndipo Fraxiparin sichoncho

Ndipo kotero onse ndiabwino

Doctor Kleksan adandiuza. Kusoka kulibe vuto kwenikweni (ngakhale ndili ndi zowawa zowawa ndipo ndikuopa kuwawa). Sanamve konse

Ngati nditenga heparin kuti ndichepetse magazi

Anandisankha Clexane

- @ marika7051 heparin nthawi yapakati? imatha kukhala yaubongo kapena fungo

Ndikumenya Kleksan tsopano, zimandipweteka!

Mimba zonse ziwiri zidasokonekera

Panalibe zovuta zilizonse, kodi anakuthandizani? @ 1978koty

Sindikudziwa kuti ndikabisala bwanji его Atsikana ndiuzeni chonde

Anandisankhira heparin analogue ya fraseparin mu moniage

Ndipo mapulateleti ndi abwinobwino

- @ marika7051 Ndimatenga woyamba. atagona mumzinda woyamba, mwatsatanetsatane, pomwe adandiuza kuti heparin anali ndi zotsatira zoyipa, sanavulazidwe konse. ndipo ndi angati omwe sanagonepo zipatala zokhazokha kapena zanzeru zokha

- @ elena51577 ttt, ayi, atsikana onse awiri akuchita bwino. Ndidayang'ana mu YouTube momwe ndikubaya bwino. poyamba zinali zowopsa, kenako monga momwe zimayembekezera popanda mantha

Dokotala adatiuza Kleksan otetezeka kwambiri

Prick dera la umbilical subcutaneally. Ndimakonda tebulo la odwala: pamimba, yosungirako idatenga mfundo ndi msondodzi. Amati sizivulaza, sizabwino basi. Pakhoza kukhala mikwingwirima kuzungulira Mchombo.

Dotolo adati mungathe ndi Kleksan.

Ine poyamba a fxiparin 0,3 kwa nthawi yayitali, kenako ziwonetsero zinafika pofufuza, sindikudziwa za izi kapena china chilichonse, koma adandisamutsira ku clexane 0,4, koma ndilibe chilichonse, tsopano ndachuluka mpaka 0,6 , tiyang'ana. Ndikutanthauza, muyenera kuyesa ndikusankha zomwe zikugwira ntchito. Ndipo sindinakhalepo ndi zotsatila pamapulogalamu)

Kolya fraksiparin onse mimba, palibe mavuto! Adotolo akuti ndi omwewo! Koma clexane alibe mulingo wa 0,3, ndipo ndikungofunikira 😊 ndichifukwa chake adayilamula!

Mu 1b, fraxeparin adabayidwa. kunalibe zoyipa. About Kleksan ndiye sanamve.

Ali ndi njira ina. Clexane, mwachitsanzo, samandithandiza, d-dimer yokha idakula. sizinawakhudze konse ndi fungo laxxiparin

- @polimishik, yemweyo pazifukwa zina, d-dimer ikukula kokha. Muli kale kuchuluka kwake. 0.6 + 0,6 patsiku

Sinthani kukhala fraxiparin, mwina clexane sikuyenera inu. 0.6 + 0,6 ndizambiri!

Sungani macheke kuchokera ku Kleksan, ndiye kuti mutha kubweza 13% ya ndalama zomwe mudalipira. Ndidalipira mimba yanga yonse ndikubweza ruble 8,000. Mutha kuwerenga zambiri mu PM kapena gulu langa https://m.vk.com/vernindfl2015

- @ persefona-85, koma munasintha bwanji kuchokera pamankhwala ena kupita pamzake? Mawa lake adasumanso wina? Kapena kodi adapuma tsiku limodzi kapena awiri?

- @marmelade nthawi yomweyo tsiku lotsatira adabera wina.

- @ persefona-85, zikomo kwambiri! ☺️ Ndiyenera kupita mawa) ndipo palibe amene akuyankha funso langa mu mtsinje. kuda nkhawa

Syringe imodzi imakhala, kutengera mtundu: 10000 anti-Ha ME, 2000 anti-Ha ME, 8000 anti-Ha ME, 4000 anti-Ha ME kapena 6000 anti-Ha ME enoxaparin sodium.