Momwe mungatengere glyformin kuti muchepetse kunenepa

Gliformin ndi mankhwala a hypoglycemic ogwiritsira ntchito pakamwa. Ndizosavuta kuganiza kuti kuchuluka kwa glucose m'magazi kuyenera "kukonzedwa" ndi odwala matenda ashuga. Muzochita zachipatala, mankhwalawa amagwiritsidwa ntchito makamaka pochiza matenda ashuga. Kodi kudya kwake kumagwirizana bwanji ndi kuchepa thupi?

Kwa nthawi yoyamba, adayamba kulumikizana ndi omanga thupi omwe amalemekeza kwambiri minofu yawo "yowuma" kotero kuti ali okonzeka kuyesa kulikonse kosafunikira kuti thupi likhale "lamankhwala otsika".

Amadziyesa okha mankhwala osiyanasiyana opangira, kulandiridwa kwake komwe kumakhala korona wokongola "mbali" monga kuchepa thupi msanga.

Gliformin ndi mankhwala omwe amachepetsa glucose ndi "oyipa" m'magazi, amachepetsa mayamwidwe amthupi, amathandizira ndikukhazikitsa zomwe zimapangitsa kagayidwe kachakudya. Pazifukwa izi, adakondedwa kwambiri ndi osewera komanso azimayi omwe akufuna kuti achepetse thupi mofulumira.

Mndandanda wa mankhwala Glformin - Metformin, Glucofage, Bagomet, Metfogamma. Zina mwa izo zimagulitsidwa m'masitolo ogulitsa, chifukwa chake zimaphatikizidwa mu gawo la ulemu wapadera pakati pa iwo omwe amalemera. Mankhwala a Hypoglycemic amtunduwu samakhala ndi zovuta zazikulu, kotero anthu ambiri amapita kukalandira kwawo mopanda mantha. Ndipo pachabe.

Madokotala a zamasewera amalimbikitsa mankhwala omwe amatchedwa Glformin kumawadi awo. Komabe, ali ndi deta yawo yonse kuti achepetse chiopsezo chokhala ndi matenda oopsa pamene akumwa mankhwalawo.

Ngati mukufunitsitsa "mapiritsi amatsenga" kuti muchepetse kunenepa, ndikuganiza zoyamba kugwiritsa ntchito mankhwala a hypoglycemic, ndikofunikira kudziwa zomwe zigawo zawo zimagwira komanso momwe Glyformin, wogwiritsidwa ntchito pakuchepetsa thupi, angakhudzire thanzi lanu.

Mapiritsi otchedwa Glformin amaphatikizira mawonekedwe awo - yogwira mankhwala a metformin hydrochloride. Amagwiritsidwa ntchito popanga zovuta za matenda amitundu iwiri. Odwala omwe ali ndi vuto lotere amafunikira mankhwalawa, ndipo kwa ena amawapanga ngati chithandizo cha moyo wonse.

Kapangidwe ka zochita zake ndikosavuta: kumalepheretsa magwiridwe azigawo a shuga m'chiwindi, kuteteza kuyamwa kwake mwachangu m'magazi. Mankhwalawa amachititsa kuti minofu ifulumizidwe mosavuta, chifukwa minofu imakula msanga, ndipo mafuta ochulukirachulukira amayaka mofulumira.

Koma chinthu chofunikira kwambiri cha mankhwala a Glformin pakuchepetsa thupi ndi kuthekera kwake kuchepetsa kuchuluka kwa insulin - mahomoni omwe amasintha mphamvu kukhala maselo amafuta. Chifukwa chake, ma carbohydrate amayamba kumizidwa ndikuwotchedwa mosiyanasiyana, ma calorie amamugwiritsa ntchito nthawi yomweyo, ndipo owonjezera satumizidwa ku "malo ogulitsa mafuta".

Pochepetsa kuchuluka kwa shuga m'magazi, mapiritsiwo nthawi imodzi amatchinjiriza njala, kuchepetsa chilakolako chambiri. Ndiye chifukwa cha zovuta izi zomwe malingaliro oti amamwe mankhwalawo ndi ochepa.

Kumwa nokha mankhwalawa sikulimbikitsidwa. Choyamba, popanda matenda a shuga, mwina simungadziwe za kuchuluka kwa shuga m'magazi anu. Kwa unyinji wa anthu, zili kale pansipa. Chifukwa chake, mumakhala pachiwopsezo chotenga vuto la hypoglycemia.

Kachiwiri, mukamagwiritsa ntchito mankhwala omwe ali ndi zosakaniza zolimba choncho, ndikofunikira kukhala ndi chitsimikizo cha 100% kuti palibe zotsutsana. Palibe aliyense wa ife amene anganenere za kusalolerana kwa zigawo za mankhwalawo, ndikudziwa motsimikiza kuti palibe ma piritsi obisika m'thupi omwe sagwirizana ndi kugwiritsa ntchito mapiritsi awa.

Chifukwa chake, mulimonse, muyenera kufunsa dokotala.

Ndipo koposa zonse, musaiwale za izi - gawo lamkango la mkango wamafuta onenepa kwambiri limakula chifukwa cha kusowa chidwi komanso chizolowezi chotsogola mu "boma" la kusachita ntchito.

Tangoganizirani - 10% yokha mwa odwala onse onenepa omwe amakhaladi ndi vuto lakutulutsa chibadwa, metabolism ndi zina zosalamulirika.

Chifukwa chake, ngati mungaganize kuti kunenepa kwambiri kwatsimikizika kukhala chifukwa cha "metabolism slowly", titha kukutsimikizirani 90% kuti izi sizowona. Ndipo metabolism ingakhale bwanji yachangu ngati mukugwiritsa ntchito nthawi yanu yonse pa ottoman muli ndi chidutswa cha pizza m'manja?

Kumbukirani - mutha kufulumizitsa njira zanu zama metabolic munjira zabwino. Zothandiza kwambiri kwa izo ndizolimbitsa thupi nthawi zonse (ngakhale ngati ndizoletsa masewera olimbitsa thupi kunyumba) komanso zakudya zazolimbitsa thupi. Mukufuna kuwopseza ndi zovuta zomwe zingachitike ngati mankhwala atha kuthana mwachangu, bwino komanso mosatetezeka?

Timalimbikitsa: ngakhale akatswiri azakudya amavomereza kuti Glyformin alibe mphamvu pakuwonongeka kwamafuta popanda kudya komanso kuphunzitsidwa pafupipafupi. Chifukwa chake, ngati chifukwa chowoneka kuti ndinu owonda kwambiri mwa inu chikhala mukulephera kudya kwambiri komanso kulephera kugwira ntchito, kumwa mapiritsi anu sikungakhale kokha koopsa komanso kopanda ntchito.

Nthawi yomweyo, pulogalamu yosankhidwa bwino yolemetsa, yomwe imaphatikizapo kudya zakudya zamagulu ochepa komanso kuchita masewera olimbitsa thupi nthawi zonse, kuphatikiza kugwiritsa ntchito mankhwalawa, imakuthandizani mwachangu kuthana ndi mafuta a 8-10 kg a thupi lanu. Chifukwa chake, musanadzifunse momwe mungatengere Glformin molondola, konzekerani kutsatira zakudya ndi masewera olimbitsa thupi mulimonse.

Kumwa mankhwalawa ayenera kukhala osamala momwe mungathere:

Njira yonse ya "chithandizo" sayenera kupitilira masiku 22 pakadali pano,
Mlingo wa chinthu chimodzi uyenera kufotokozedwa ndi wowonera endocrinologist,
Mapiritsi amatengedwa ndikudya kapena mutatha kudya ndi madzi okwanira.
Mlingo wonse wa mankhwalawa sayenera kupitirira 500-600 mg patsiku. Anthu ena amakonda kuphwanya kuchuluka kwa zinthu zingapo,
Pa gawo loyambirira la maphunzirowa, mumatha kumva zovuta zina zofanana ndi kuwonetsa kwa toxosis - nseru, kusowa kwa chakudya, ulesi ndi kusachita chidwi. Nthawi zambiri onse amadzipaka okha pakatha masiku atatu kapena atatu.

Ganizirani zolakwika zonse zomwe mungatenge:

Lactic acidosis (lactic acidosis),
Zambiri za impso ndi chiwindi,
Matenda a Mtima,
Nthawi yogwira ntchito komanso yodziwitsa ena,
Uchidakwa wopitilira muyeso kapena poyizoni m'mbuyomu.
Mimba komanso kuyamwa
Hypersensitivity kumagawo.

Mukamatsatira malamulo onse ndi ndandanda, Glformin adzakuthandizani kuti muchepetse njira yochepetsera thupi ndi 2-3 makilogalamu pamwezi.

Ngati, mukumwa Glformin, mumapeza zotsatirazi zoyipa, funsani dokotala nthawi yomweyo!

Kusanza kwambiri
Matenda okhazikika
Kukoma kwazitsulo pakamwa
Mikhalidwe yosintha
Kukuwotcha
Kupweteka kwam'mimba
Khungu lotupa lachilendo kwachilendo.

Kuchokera pamalingaliro azachipatala, kugwiritsa ntchito mankhwala osavomerezeka kwa anthu odwala kwambiri ndi cholinga chochepetsa thupi ndi zopanda pake kwenikweni.

Ndipo timachirikiza mokwanira udindo uwu wa madotolo. Yesani kuchepa thupi kunenepa musanayambe kutaya mtima ndikutembenukira kwa othandizira a hypoglycemic.

Momwe mungagwiritsire ntchito Glyformin bwino kwambiri, kuwunika kwa madokotala ndi odwala matenda ashuga

Gliformin ndi chithunzi cha ku Russia cha mankhwala oyambirira achi French Glucofage. Zomwe zimagwiritsidwa ntchito zomwe zimagwirizana ndi metformin.Mankhwala odziwika kwambiri komanso olemekezeka kwambiri omwe ali ndi umboni wamphamvu wochita bwino ndi chitetezo amagwiritsidwa ntchito ku monotherapy komanso panjira yovuta ya matenda a shuga a 2.

Gliformin ali ndi zovuta zochepa zoyipa ndipo amayenda bwino ndi ena omwe amachepetsa shuga pamlomo, komanso ndi insulin.

Kupanga ndi mawonekedwe a kumasulidwa

Pa neti yogawa, mankhwalawa amaperekedwa mwa mapiritsi. Amasiyanitsidwa ndi mtundu ndi kulemera kwake: mu zoyera za 0,5 g pazoyambira, mu kirimu - 0,85 kapena 1 g. Glyformin imayikidwa zidutswa 60. m'mipensulo yamapensulo apulasitiki yokhala ndi cholowa.

Chithandizo chophatikizika cha mankhwalawo ndi metformin hydrochloride. Mtundu wopangidwa ndi wautali wa Glyformin - Glyformin Prolong.

Momwe glyformin imagwirira ntchito

Mankhwala a hypoglycemic ndi a gulu la biagunides. Limagwirira zake zimakhazikika pakuwonjezera chidwi cha maselo a cell kuti endo native insulin.

Mwa zina zotulukapo za mankhwalawa:

Kukula kwa basal glycemic chifukwa chakuwongolera kwa glycogen omasulidwa,
Kuletsa kwa kupanga kwa glucose kuchokera ku mafuta ndi mapuloteni,
Kuletsa kuyamwa kwa m'mimba,
Kuchepa kwa kukana insulini,
Imathandizira kusintha kwa glucose kukhala lactate,
Kukhazikitsa kwa glucose kutengera minofu, komwe imakonzedwa kwathunthu,
Kusintha kwa lipid wamagazi: kuchuluka mu HDL, kuchepa kwa kuchuluka kwa cholesterol, triglycerol ndi LDL.

Ubwino wofunikira wa Glyformin ndikuti samatumiza katundu kawiri pa kapamba, samalimbikitsa maselo a b omwe ali ndi vuto lopanga insulin yawo, chifukwa mu mtundu 2 matenda ashuga awonongeka kale 50-60%.

Mankhwalawa, mosiyana ndi mankhwala ena othandizira odwala matenda ashuga ndi insulin, samathandizanso kuti achepetse thupi, ndipo akamagwiritsa ntchito nthawi yayitali amachepetsa thupi. Kwa odwala matenda ashuga omwe ali ndi matenda amtundu wa 2, iyi ndi katundu wofunikira kwambiri, chifukwa kunenepa kwambiri ndi chimodzi mwazomwe zimayambitsa matenda ashuga.

Kwa Gliformin, malangizo ogwiritsidwira ntchito awonanso kuti mankhwalawa amachepetsa magazi ndikuletsa kuphatikizira kwa mapulateleti. Pambuyo polowa m'matumbo am'mimba, metformin imatengedwa mwachangu kwambiri ndi bioavailability wa 60%.

Pachimake pachimake chimawonedwa patatha maola awiri. Mankhwalawa sikugwirizana ndi mapuloteni am magazi. Ma metabolabol amachotsedwa ndi impso mwachilengedwe.

Ndani amasankhidwa Gliformin

Glyformin sikuti amangokhala mankhwala ochepetsa shuga kwa odwala matenda ashuga: kuwonjezera pa ma endocrinologists, akatswiri azamankhwala, akatswiri a zamankhwala, othandizira ndipo ngakhale oncologists akuigwiritsa ntchito molimbika.

Mankhwala apadziko lonse atha kukhala othandiza:

Mtundu wachiwiri wa matenda ashuga, ngati kusintha kwa moyo sikupereka zotsatira zomwe mukufuna,
Mtundu woyamba wa shuga, kuwonjezera pa insulin,
Ovary Polycystic,
Metabolic syndrome
Kupewa kukalamba
Kuchita masewera olimbitsa thupi komanso kuwonda.

Metformin imagwiritsidwanso ntchito pochiza ana onenepa kwambiri komanso mtundu wa matenda ashuga achikale kuposa zaka 10. Zaka zaposachedwa, vutoli, makamaka m'maiko otukuka, lathandizika kwambiri.

Normalizing glycemia, Glyformin amagwira ntchito ngati antioxidant yomwe imachepetsa kukalamba kwa thupi: imakhazikika pakuthamanga kwa magazi, imayenda bwino kwamitsempha, imalepheretsa kukula kwa atherosulinosis ndi kulephera kwa mtima.

Popeza metformin imachotsedwa impso, ndikofunikira kuwunikira nthawi zonse, makamaka paubwana komanso pamaso pa ma pathologies aliwonse mbali iyi. Kamodzi pa miyezi isanu ndi umodzi iliyonse, mulingo wa lactate umawunikiranso.

Momwe mungagwiritsire ntchito mankhwalawa ndi mphamvu yokwanira

Malinga ndi malangizo ndi pharmacokinetics a Glformin, iyenera kudyedwa ndi chakudya kapena pambuyo pake. Mlingo ndi pafupipafupi wa makonzedwe amasankhidwa ndi endocrinologist, poganizira kuopsa kwa matenda ashuga, matenda ofanana, thanzi limodzi, momwe munthu amvera mankhwalawo.

Mapiritsiwo ndi amtundu-wowoneka bwino pamtundu wowala ndipo ali ndi chophatikizira metformin.

Zowonjezera: sorbitol, povidone, macrogol (polyethylene glycol), calcium phosphate dihydrate, stearic acid.

Pharmacodynamics ndi pharmacokinetics

Mankhwala a hypoglycemic omwe ali mgululi khwawa, idapangidwa kuti igwiritsidwe ntchito mkati. Amatha kuchepetsa gluconeogenesis mu chiwindi, kuchepetsa mayamwidwe a shuga kuchokera m'matumbo insulin.

Mankhwala samakhudza kupanga insulin maselo a beta a kapamba. Zotsitsa LDL misinkhu ndi triglycerides mu kapangidwe magazi. Kukhazikika kapena kuchepetsa thupi.

Mphamvu ya fibrinolytic idadziwika mwa kupondereza minofu ya plasminogen activator inhibitor.

Mkati mwa thupi metformin zotengeka mwachangu kuchokera mumimba. Pazitali ndende zikuchokera magazi a m'magazi wapezeka pambuyo 2-2,5 maola

The bioavailability wa chinthu pafupifupi 50-60%. Mankhwalawa sakukhudzana ndi mapuloteni a plasma. Kuphatikizidwa kwadziwika metformin mu tiziwalo tating'ono, impso ndi chiwindi.

Kuchokera mthupi, chinthucho chimapukusidwa ndi impso, pafupifupi osasinthika.

Contraindication

Sitikulimbikitsidwa kumwa mankhwalawa ndi:

wodwala matenda ashuga komanso zabwino
ketoacidosis,
matenda opatsirana
zotupa za chiwindi ndi impso,
mtima kulephera kapena mtima kulephera,
pachimake myocardial infaration,
mkaka wa m'mimba, pakati.

Malangizo ogwiritsira ntchito Glformin (Njira ndi Mlingo)

Monga momwe malangizo a Glformin amagwiritsidwira ntchito, mapiritsi amatengedwa pakamwa. Pankhaniyi, masiku atatu oyamba, odwala amapatsidwa 500 mg mpaka 3 pa tsiku limodzi, nthawi yomweyo kapena akudya. Kenako mlingo umakulitsidwa pang'onopang'ono mpaka 1 g. Nthawi zambiri, mankhwalawa amakonzedwa tsiku lililonse ndi 0,1,2.2 g.

Bongo

Mu nkhani ya bongo zingachitike lactic acidosiszakupha. Cholinga chake chachikulu ndikukula. metformin chifukwa cha kuwonongeka kwaimpso.

Kalelo kumayambiriro: mseru, kusanza, kutsekula m'mimba, kufooka wamba, kutsika kwa kutentha, kupweteka kwam'mimba ndi minofu, kuchepa kwa mavuto bradyarrhythmia.

Kenako kupumira mofulumira chizungulire kusazindikira bwino komanso kukula chikomokere.

Zizindikiro zikaoneka lactic acidosis muyenera kusiya kumwa Gliformin.

Kupitanso patsogolo kumachitika kuchipatala, motero wodwala amafunikira kuchipatala, kukhazikitsa ndende ya lactate, kutsimikizira matendawa.

Njira zoyenera hemodialysiskuthandiza kuchotsa m'thupi mkaka ndi metformin. Mankhwala owonjezeranso amphongo amachitidwanso.

Kuchita

Ndi munthawi yomweyo kugwiritsa ntchito zotumphukira sulfonylureas, acarbose, insulin, NSAIDs, Mao zoletsa ndi ACE, oxytetracyclinezotumphukira onjezerani, cyclophosphamidebeta-blockers atha kupititsa patsogolo zotsatira za hypoglycemic za Gliformin.

Kuphatikiza kwa mankhwalawa komanso GKS, kulera kwamlomo epinephrineamphanomachul Glucagon, mahomoni a chithokomiro, thiazides ndi "Loop" okodzetsa, phenothiazine zotumphukira ndi Nicotinic acid amachepetsa mphamvu yake ya hypoglycemic.

Cimetidine amaletsa kuchotsedwa metforminzomwe zimawonjezera chiopsezo cha chitukuko lactic acidosis.

Kuphatikiza kwa Gliformin ndi anticoagulants ochokera ku coumarin zitha kufooketsa mphamvu zawo.

Zofananira za Gliformin

Zofanizira zazikulu za Gliformin zimayimiriridwa ndi mankhwala osokoneza bongo Glucophagus, Dformin, Diaberite, Diabetesos, Metformin, Diabexil, Diguanil, Gliguanid, Melbin, Mellitin, Glucoran, Metiguanid, Modulan ndi ena.

Kugwiritsa ntchito mowa komanso zinthu zina zomwe zimakhala ndi ethanol kumatha kubweretsa chitukuko lactic acidosis.

Ndemanga za Gliformin

Monga ndemanga ya Glformin, ikhoza kutengedwa ngati odwala omwe akudwala matenda ashuga, komanso matenda osiyanasiyana a metabolic. Kuphatikiza apo, mankhwalawa nthawi zambiri amatengedwa ndi amayi omwe amafuna kuti athetse msanga kuchuluka kolemera.

Komabe, anthu ena omwe adatenga Glformin kuti achepetse thupi, zindikirani kuti adatha kubwezeretsanso kuchuluka kwa mahomoni ndikuwoneka kuti achepetsa thupi.

Pamodzi ndi izi, pali malipoti ambiri akuchenjeza kuti kutenga Glformin kuti achepetse mafuta osavomerezeka sikulimbikitsidwa ngati palibe umboni wa izi.

Mukhozanso kukumana ndi nkhani zomwe kulandira mankhwala ndi mankhwalawa kumabweretsa chitukuko cha mavuto, mwachitsanzo, kudzimbidwa, kufooka, mutu ndi zina zotero.

Monga mukudziwa, Gliformin ndi mankhwala omwe amatha kusintha thupi, komanso osakhala ndi chiyembekezo. Chifukwa chake, munthawi ya chithandizo, kuyang'anira pafupipafupi momwe odwala alili ndi kuyanjana ndi katswiri amafunikira.

Mtengo wa Gliformin, komwe mugule

Mtengo wa Glyformin 1000 g umasiyana ndi ma ruble 280-350.

Mutha kugula mapiritsi a 500 kapena 800 mg pamtengo wa ma ruble 120 mpaka 290.

Gliformin mapiritsi 500 mg 60 ma PC Akrikhin

Gliformin 500mg No. 60 mapiritsiAkrikhin HFK OAO
Gliformin 850mg No. 60 mapiritsiAkrikhin HFK OAO
Gliformin 1000mg No. 60 mapiritsiAkrikhin HFK OAO
Glformin Prolong 1000mg No. 60 mapiritsi olimbikitsidwa otulutsidwaAkrikhin HFK OJSC

LAPANI ZOTSATIRA! Zambiri pamankhwala omwe ali pamalowo ndizokhudza zonse, zomwe zimatengedwa kuchokera kwa anthu ndipo sizingagwiritsidwe ntchito ngati lingaliro la kugwiritsa ntchito mankhwalawa munthawi ya chithandizo. Musanagwiritse ntchito mankhwala a Glformin, onetsetsani kuti mwawonana ndi dokotala.

Mfundo yofunika yotsimikizira

Ichi ndi mankhwala a hypoglycemic. Ndiye kuti, ntchito yake yayikulu ndikuchepetsa magazi. Ichi ndi chifukwa chachikulu chomwe Metformin adakhazikitsidwa ndi chithandizo cha matenda a shuga a 2 komanso boma la prediabetes.

Komabe, momwe zimakhalira zingakhale zothandizanso pakuchepetsa thupi.

Mankhwalawa amakhudza thupi m'njira zitatu zazikulu, iliyonse yomwe ingathandize kuchepetsa thupi.

Amachepetsa kupanga shuga m'chiwindi.
Kuchulukitsa kuchuluka kwa glucose wogwiritsidwa ntchito ndi minofu ya minofu.
Amachepetsa kuchuluka kwa lipolysis (nthawi zina imakhala yothandiza kuti muchepetse thupi, chifukwa imachepetsa kupanga shuga).

Mphamvu ya mankhwalawa imapangitsa kuchepa kwa kukokana kwa minofu ya thupi kupita ku insulin (chimodzi mwazifukwa zazikulu zolemera kwambiri, makamaka m'mimba), komanso kuchepa kwa chilakolako chofuna kudya.

Kodi zimathandizanso kuchepa thupi?

Iwo omwe akufuna kuchepetsa thupi pa mankhwalawa nthawi zambiri amafuna kuti awerenge ndemanga zochepetsera thupi pogwiritsa ntchito metformin. Izi sizolondola konse. Popeza "zowunika zenizeni zakuchepera" nthawi zambiri zimalembedwa ndi opanga othandizira zakudya kuti achepetse kunenepa komanso alibe chochita ndi zenizeni.

Chifukwa chake, ndibwino kungoyang'ana pa zomwe asayansi omwe adapeza atayesedwa. Metformin yakhala ikugwiritsidwa ntchito kwa nthawi yayitali, kuphatikiza kuwonda. Chifukwa chake, pali kuchuluka kwakulu kwazidziwitso zamankhwala zamankhwala.

Ndi malingaliro ati enieni omwe akatswiri adawona? Kukhazikitsidwa kuti metformin imathandizira kuchepetsa thupi, koma sizichita bwino kwambiri.

Mukamamwa pachaka popanda kusintha zakudya ndi moyo, mumatha kutaya makilogalamu atatu.

Mukasinthira zakudya zoyenera, ndiye kuti mutha kutaya makilogalamu 5-7 m'miyezi 6.

Ndiye kuti, ponena za momwe zimakhalira pakuchepetsa thupi, mankhwalawa amawonetsa zoposa zotsatira zochepa. Kuphatikiza apo, akuwonetsa kukhathamiritsa kwakadali kantchito kadyedwe kathanzi komanso kulimbitsa thupi. Komanso, maphunziro ndi ofunika kwambiri, chifukwa metformin imakhudza kugwiritsidwa ntchito kwa shuga ndi minofu. Koma kuti iyambitse njirayi, minofu iyenera kugwira ntchito.

Mwachidziwikire, mutha kuchepa thupi pakudya moyenera komanso kuchita masewera olimbitsa thupi popanda mapiritsi.Komanso, atasiya kumwa mankhwalawo, kulemera kwake kumabwereranso ku zomwe adachita m'mbuyomu.

Malangizo ogwiritsira ntchito kuwonda

Metformin imapezeka m'mitundu iwiri: kuchita zinthu mwachangu komanso kwautali.

Makonzedwe oyamba a mankhwala omwe amagwira ntchito mwachangu amakhala 500 mg kawiri pa tsiku, kapena 850 mg kamodzi patsiku.
Chifukwa chake, mankhwalawa amatengedwa sabata limodzi tsiku lililonse.
Sabata yotsatira, mlingo ukuwonjezeka ndi 500 mg.
Pang'onopang'ono (kuwonjezera ndi 500 mg pa sabata), mlingo umasinthidwa kukhala 2000 mg patsiku. Mlingo waukulu kwambiri ukhoza kukhala 2550 mg.

Kwa metformin munthawi yayitali, malangizowo akuwoneka ngati awa:

Imwani 500 mg kamodzi patsiku sabata yoyamba,
onjezerani mlingo ndi 500 mg pa sabata mpaka mlingo womaliza wa 2000 mg ufike.

Malangizo onse

Ndikofunika kugawa kuchuluka kwa mankhwalawa kuposa 500 mg mu 2-3 waukulu.
Tengani ndi zakudya zamafuta ochepa.
Imwani ndi kapu yodzaza ndi madzi.

Glformin, formin, kapena metformin: Ubwino ndi chiyani? Zonse zili chimodzimodzi. Glformin ndi formine ndi mayina ena ogulitsa pazinthu zomwezo.

Kuopseza kwa lactic acidosis

Choyipa choopsa kwambiri cha metformin ndi lactic acidosis, yomwe imayamba pamaso pa matenda a impso mwa munthu, vuto la kuchepa madzi m'mimba, kulephera kwa mtima, ndikuyambitsa kumwa kwakukulu.

Chifukwa chake, metformin ndi yoletsedwa kutenga ndi:

matenda a impso
mu matenda a diabetes ketoacidosis.

Komanso ndi chisamaliro chachikulu chikuyenera kugwiritsidwa ntchito ngati:

matenda a chiwindi
matenda a mtima, makamaka kugunda kwamtima mwadzidzidzi,
senile (wopitilira 80) ndi ana osaposa zaka 10),
uchidakwa
matenda opatsirana.

Munthawi zonsezi, musanayambe kumwa mankhwalawa, muyenera kufunsa dokotala.

Matenda a lactic acidosis, omwe amatha kupezeka pomwa mankhwalawo, ndiwosapha. Chifukwa chake, muyenera kufunafuna thandizo la kuchipatala ngati, mutangomwa mankhwalawo, zizindikiro zotsatirazi zachitika:

kupweteka kwa minofu kapena kufooka kwambiri,
dzanzi kapena kumva kuzizira m'manja ndi m'miyendo,
kupuma movutikira
chizungulire ndi kukomoka,
kupweteka m'mimba ndi mseru komanso kusanza,
kugunda kwamtima pang'ono komanso kosakhazikika.

Zotsatira zina zoyipa

Kuphatikiza pa lactic acidosis, mankhwalawa angayambitse kukulitsa zotsatira zina zoyipa, makamaka zomwe zimakhudzana ndi zizindikiro zosasangalatsa kuchokera m'matumbo am'mimba. Uku ndi kutsegula m'mimba, kusanza, komanso kupweteka kwam'mimba.

Metformin ili ndi vuto linanso limodzi. Uku ndi kuchepa kwa vitamini B12. Ngakhale kuti chodabwitsachi chimatsimikiziridwa mwasayansi, iwo samanena zambiri za icho. Kungoti samapezeka kawirikawiri. Chowonadi ndi chakuti madokotala ochepa amapereka chithandizo cha mavitamini awa kwa odwala awo, ngakhale atakhala ndi madandaulo oyenera.

Zizindikiro zoyambirira za kuperewera kwa Vitamini B12 ndizovuta kuzama komanso kuiwalika, kufooka kwa minofu, komanso kutopa kwambiri.

Chifukwa chiyani kutenga metformin?

Metformin ndi dzina la pophika mankhwala osokoneza bongo kuti muchepetse shuga. Metformin imagwira thupi motere:

imapangitsa chidwi cha insulin,
Amachepetsa kuyamwa kwa m'mimba,
bwino shuga chiwopsezo cha maselo.

Metformin sikuti imalimbikitsa kupangika kwa insulin yake, koma imangoyambitsa kuyankha kwa maselo mu timadzi timeneti. Tiyenera kumvetsetsa kuti ndi mtundu wa 1 shuga, metformin imatha kutengedwa, koma sichilowetsa jakisoni wa insulin tsiku lililonse.

Izi zimathandizira kagayidwe kazakudya m'thupi la wodwala yemwe ali ndi matenda ashuga. Kukonzekera kwa Metformin kukuwonetsedwa pochiza odwala omwe ali ndi matenda a shuga a 2 ndicholinga:

kuchepa kwamtima
matenda a kagayidwe kachakudya,
kuwonda
kutsika kwa shuga m'magazi.

Mankhwalawa amathandizanso kuchepetsa chiopsezo chotenga zovuta kuchokera ku matenda ashuga.Amayikidwa ngati pali chiopsezo cha matenda amtima.

Zimagwira bwanji?

Mankhwala aliwonse omwe ali ndi metformin amasiyanasiyana nthawi yayitali komanso mlingo. Pali metformin yomwe imatenga nthawi yayitali. Izi zikutanthauza kuti mankhwalawa sagwirira ntchito mwachangu, koma pang'onopang'ono, kwakanthawi, ndikuchepetsa shuga m'magazi. Monga lamulo, mankhwalawa ali ndi liwu loti "lalitali" m'dzina, mwachitsanzo, Glucofage Long.

Kumwa mankhwala monga Glucofage Long kumathandizira kusintha kagayidwe kachakudya kagayidwe kake komanso kuchepetsa shuga m'magazi, komanso kumatithandizanso kukhala ndi mapuloteni komanso bilirubin. Komabe, izi sizitanthauza kuti mankhwalawa amachotsedweratu zakudya za shuga.

Kukonzekera kwa Metformin

Mankhwala odziwika kwambiri a metformin ndi Glucofage, Glybomet kapena Siofor. Mankhwalawa amatchulidwa kwambiri kwa odwala matenda ashuga kuti asinthe matenda awo.

Nthawi zambiri, odwala amakhala ndi chidwi ngati adalembedwa Glibomet, Glyukofazh kapena Siofor - zomwe angatenge bwino komanso ndi mankhwala ati omwe angakonde.

Tiyenera kumvetsetsa kuti Glybomet, Glucophage ndi Siofor ndi mayina amalonda ogulitsa mankhwalawo. Zomwe zimagwiritsidwa ntchito mwa iwo ndizofanana ndipo metformin ndi gawo la Glibomet, mapiritsi a Glucofage ndi Siofor, ndipo kuchuluka kwa thunthu ndi chimodzimodzi.

Nthawi zambiri pamakhala funso loti mapiritsi a mankhwala - metformin, Glybomet kapena Glucofage ayenera kumwa, omwe ali bwino komanso othandiza kwambiri.

Madokotala amatsimikizira kuti metformin, Glybomet kapena Siofor - chisankho chotere sichiyenera kupangidwa, ndipo chomwe chiri bwino - izi sizingatheke kunena, chifukwa mankhwalawa amagwiranso ntchito chimodzimodzi. Glucophage Long imagwira ntchito mwanjira yomweyo ndipo Metformin Long - ndizofanana.

Zomwe adotolo adalimbikitsa, ndibwino kuti muzitenga, mosatengera dzina - lingakhale Siofor kapena Glucofage Long kapena mankhwala ena ali ndi metformin, yoyenera mtundu 2 shuga.

Momwe mungasankhire mankhwala?

Pali mankhwala ambiri okhala ndi mayina osiyanasiyana, koma machitidwe omwewo, kotero kusankha kwa mankhwalawa ndikusiyidwa kwa dokotala. Kusiyanitsa pakati pa mapiritsi osiyanasiyana ndikuti mankhwala ena amatenga nthawi yayitali. Nthawi zambiri chidziwitsochi chimafotokozedwa m'dzina, mankhwalawa amalembedwa ndi mawu oti "lalitali."

Mankhwala amachititsa zovuta zingapo. Kuti mupewe izi, ndikofunikira kutsatira malamulo awa:

Kugwirizana ndi zakudya zomwe zalimbikitsidwa
zolimbitsa thupi zolimbitsa thupi
kumwa mankhwalawa monga adalimbikitsa ndi dokotala.

Kudzipatsa nokha kukhala koopsa ku thanzi, chifukwa chake ngati pakufunika kuwongolera kuchuluka kwa shuga ndi mankhwala, muyenera kudalira dokotala wanu posankha mankhwala.

Mafunso wamba okhudzana ndi momwe Glucofage, Glibomet, Glformin kapena Siofor ndi metformin amasiyana komanso ndi iti mwa iwo omwe akutenga bwino, akuwonetsa kuti dokotalayo adapereka mankhwala angapo oti asankhe, kuti wodwalayo athe kuphunzira zowunikirawo ndikusankha yekha mankhwalawo.

Mankhwala othandizira

Mankhwala ochepetsa shuga ali ndi zovuta zingapo zoyipa. Kuti muchepetse chiwopsezo cha zotsatira zosakonzeka, madokotala nthawi zambiri amapereka mankhwala ndi taurine pazomwe zimapangidwira, mwachitsanzo, Dibicor.

Dibicor imatha kutengedwa ngati chithandizo cha adjunct mtundu uliwonse wa matenda ashuga. Mapiritsi amathandizira pamtima wamatenda, motero Dibicor nthawi zambiri amalembedwa pakakhala chiwopsezo cha kukhala ndi thrombosis ku matenda ashuga.

Dibicor imapanganso matenda a bilirubin, omwe amawonjezera omwe nthawi zambiri amawonedwa odwala omwe ali ndi matenda osokoneza bongo akakhala onenepa.

Gawo lofunika kwambiri popewa matenda ashuga ndi mtundu wa kulemera kwa wodwalayo. Kunenepa kwambiri kumangokulitsa nthawi yamatendawa.

Nthawi zambiri mumamva kuti madokotala amapereka Reduxin kwa odwala, mankhwala omwe amasintha njira za metabolic komanso amathandizira kuchepetsa wodwalayo.

Reduxin amatengedwa pokhapokha ngati adokotala adamuwuza.Pankhaniyi, wodwala amathanso kutenga Dibicor, ngati palibe contraindication.

Momwe mungagwiritsire ntchito zomwe mungaphatikize ndi Dibikor - izi zimafotokozedwa m'mayendedwe. Popanda kuthandizidwa ndi dokotala, Dibikor ndi Reduxin satengedwa, ngakhale kuti mankhwala atha kugulidwa popanda mankhwala mu mankhwala aliwonse.

Nthawi zambiri mumamva funso loti ndi liti - mapiritsi a Dibicor kapena Glucofage. Funso lotere ndilolakwika. Dibikor simalamulira kuchuluka kwa shuga, mosiyana ndi mapiritsi a Glucofage, koma amalimbitsa dongosolo lamtima. Mankhwalawa amatha kugwiritsidwa ntchito molumikizana ndi mankhwala a hypoglycemic, koma okhawo omwe adalangizidwa ndi dokotala.

Kuchepetsa thupi ndi Metformin

Mapiritsi a Metformin amathanso kutengedwa ndi amayi athanzi omwe onenepa kwambiri. Izi zimathandiza kukonza kagayidwe kachakudya mthupi, chifukwa chake, umalimbana kwambiri ndi kunenepa kwambiri. Ndemanga zikuwonetsa kuti kuchepa thupi mutatenga Reduxin, Glibomet, mapiritsi a Glformin amafika kilogalamu khumi pamwezi.

Komabe, apa zikuyenera kumvetsetsa, musanayambe kumwa metformin ndi Siofor, momwe mankhwalawa amagwirira ntchito komanso kusiyana pakati pa kuchepa kwa thupi ndi kuchepa kwa thupi polimbikitsa njira za metabolic ndi mankhwala.

Ndikothekadi kuti muchepetse thupi mwachangu ndi mapiritsi, koma muyenera kutsatira zakudya komanso masewera olimbitsa thupi. Iwo omwe akufuna kuchepetsa thupi nthawi zambiri amakhala ndi chidwi chofuna kusankha - Metformin, Glucophage Long kapena Siofor, komanso zomwe zimadziwika bwino ndi thupi. Nthawi zambiri, ndemanga zimalimbikitsa kutenga Glucophage Long.

Izi ndichifukwa choti mankhwalawa amakhudza kwambiri m'mimba, samayambitsa kugaya chakudya komanso samakhudza bilirubin.

Kuti muchepetse kunenepa, ambiri amakonda Glyformin kapena Glucofage, ndipo ngati mukukayika, muyenera kufunsa dokotala yemwe anganene kuti ndibwino kutenga wodwala wina.

Ndikofunika kukumbukira kuti mapiritsiwa adapangira zochizira matenda a shuga ndipo ndi mankhwala. Amayambitsa mavuto angapo ndipo amafunikira kutsatira njira yoyenera. Chifukwa chake, ngati mukufuna kuchepa thupi pogwiritsa ntchito metformin, muyenera kukambirana kaye ndi endocrinologist ndi akatswiri azakudya.

Mapiritsi a Glucophage ndi Siofor pochiritsa kunenepa sikuti ndiosiyana, kusiyana kokha ndi wopanga ndi dzina. China china chomwe Glucophage chimasiyana ndi Siofor ndi kuchuluka kwa mafakisi, mankhwala oyamba ndi otchuka komanso ochulukirapo.

Chithandizo china chothandiza pakuchepetsa thupi ndi Reduxin. Nthawi zambiri amawapatsa odwala omwe ali ndi shuga omwe sangathe kuchepetsa thupi kudzera pakudya komanso masewera olimbitsa thupi.

Reduxine imasiyanitsidwa ndi mtengo wake wotsika mtengo komanso njira yosavuta yotulutsira. Tengani Reduxin tikulimbikitsidwa nthawi 1 patsiku, pakudya koyamba m'mawa.

Reduxin imapezeka m'mapapu, omwe amamezedwa mosavuta ndikuyamwa bwino ndi thupi.

Ngati mukufuna kusiya glucophage yomwe idatengedwa kuti muziwongolera thupi, njira yabwino yotsatsira mankhwalawa ndi Reduxin.

Mitundu ya mankhwala ndi malangizo ogwiritsira ntchito

Musanaphatikizire mankhwala a Gliformin munthawi yonse ya chithandizo, ndikofunikira kuti muphunzire mawonekedwe ndi malamulo ogwiritsira ntchito. Glyformin amadziwika kuti ndi mankhwala amkamwa omwe zochita zawo zimafuna kuchepetsa shuga m'magazi odwala matenda ashuga. Amapezeka m'mitundu iwiri: piritsi ndi piritsi yovala filimu. Chofunikira chachikulu pa mankhwalawa ndi metformin hydrochloride.

Zowonetsa kugwiritsa ntchito mankhwalawa ndi izi:

lembani 1 ndikulemba matenda ashuga 2
kunenepa kwambiri.

Monga lamulo, Gliformin itha kugwiritsidwa ntchito kupumulira zizindikiro zonsezi monga gawo la monotherapy komanso ngati gawo la zovuta mankhwala.

Contraindrum kumwa mankhwala a Glformin atha kukhala awa:

kusalolera kwa yogwira mankhwala.
pachimake matenda a shuga: precoma, chikomokere, hypoglycemic ketoacidosis,
matenda owopsa a chiwindi, impso ndi kugaya chakudya, mtima dongosolo,
uchidakwa wambiri,
Mimba ndi kuyamwa
zaka zopitilira 60.

Asanayambe kumwa mankhwalawa, wodwalayo amafunika kufufuza mozama, zomwe zingathandize kudziwa zomwe zimachitika m'thupi ku mankhwalawo. Pochitika kuti mkhalidwe wa thupi udadziwika kuti umayanjana ndi contraindication, fanizo la Glyformin (Glucofage, Diguanil, Fortmetin, ndi ena otero) zimaperekedwa kwa wodwala. Ngati mayesowa adachita bwino ndipo dokotala yemwe adapezekapo adapereka kuwala kwagwiritsidwe ntchito ka Glformin, ndikofunikira kuti mutengeko molingana ndi dongosolo lenileni la wodwala aliyense.

Malangizo ogwiritsira ntchito mankhwala Glformin ndi awa:

Mapiritsi a Gliformin amayenera kumwedwa kwathunthu ndi chakudya kapena mukatha kudya ndi madzi.
Mlingo wa tsiku ndi tsiku wa mankhwalawa sayenera kupitirira 3. Chifukwa chake, kuwerengetsa kwa mankhwalawa m'masiku oyamba a 10 mpaka 10 a mankhwalawa kumatha kusintha kuchokera ku 0,5 mpaka 1 g yogwira ntchito maola 24 ndipo zimasiyana malinga ndi kuchuluka kwa shuga m'magazi a wodwala.
Pa kukonza mankhwalawa, mlingo wa mankhwalawa ukhoza kuyambira 1.5 mpaka 2 g ndipo umagawidwa pawiri.
Akuluakulu amakhazikitsidwa 1 g ya Glformin kamodzi patsiku.
Pankhani ya zovuta za metabolic, chithandizo chimalimbikitsidwa kuyimitsa kapena kuchepetsa Mlingo wa tsiku ndi tsiku.

Ndikofunika kukumbukira kuti mankhwalawa amayenera kumwedwa pokhapokha pokhapokha pakuyang'aniridwa ndi adokotala komanso pakulimbikitsidwa kwake. Kugwiritsa ntchito molakwika mankhwala kungayambitse matenda a impso, chiwindi ndi m'mimba.

Posachedwa, kuti achepetse zovuta zomwe zingachitike podzidzidzimutsa, Glformin m'mafakitesi adangotulutsidwa ndi mankhwala okha.

Makhalidwe ndi malangizo a Glyformin Pronge

Chimodzi mwa mitundu ya mankhwala omwe aperekedwa ndi mankhwalawa Glyformin Prolong. Mankhwalawa amatanthauza mankhwala osokoneza bongo okhazikika. Izi ndichifukwa choti zomwe zili muzochita zake zimapamwamba kuposa momwe mankhwalawo alili. Gawo la metformin hydrochloride m'gawo limodzi ndi 1000 mg. Kutulutsa kwamtundu: mapiritsi okhala ndi chisonyezo kuti mupumule.

Monga lamulo, zikuwonetsa ndi zotsutsana pakugwiritsira ntchito Glyformin Prolong ndizofanana muyezo wa mankhwalawa. Komabe, pali kusiyana kumodzi kofunikira. Mankhwalawa amavomerezedwa kuti azigwiritsidwa ntchito ndi ana azaka 10, onse mu mawonekedwe odziyimira pawokha komanso monga gawo la zovuta mankhwala.

Malangizo otenga Glyformin Prolong ndi awa:

Mankhwalawa amayenera kumwa pakudya / mutatha kudya, kumwa madzi ambiri.
Ndi monotherapy, muyeso woyamba wa achikulire uyenera kukhala 500 mg (theka la piritsi) katatu patsiku kapena 850 mg katatu. Ngati ndi kotheka, Mlingowo umasinthidwa pang'onopang'ono mpaka 1000 mg, ndikuwonjezera malire a kudya kwa 2-3 g pa maola 24.
Kuphatikiza mankhwala, muyenera kumwa Glyformin Prolong, 500-850 mg katatu patsiku.
Mu monotherapy ya ana, muyenera kumwa 500-850 mg 1 nthawi patsiku, kapena kuswa 1000 mg 2 times (500 mg mu mlingo umodzi). M'pofunika kuwonjezera mlingo wa mankhwala 2-3 ga maola 24 sabata lililonse.

Ndikofunika kukumbukira kuti pambuyo pa masiku 10-15 othandizira, ndikofunikira kusintha mlingo wa metformin hydrochloride potengera zomwe zili mu insulin m'magazi. Dokotala wokha ndi yemwe ayenera kusintha njira yochizira.

Ndemanga za Makasitomala

Kuphatikiza pa kudziwana ndi mawonekedwe ndi malangizo a mankhwalawo, chifukwa chothandiza kwambiri pakulimbikitsanso kuti muphunzire ndemanga za ogwiritsa ntchito ena. Nawa ena a iwo.

Alexandra, wazaka 45.

"Posakhalitsa adazindikira magawo oyambira a shuga, chifukwa cha izi adangokhala ndi mantha. Ndimaganiza kuti alembe mankhwala ochuluka. Dokotala adamulembera Gliformin 2 kawiri pa tsiku, 0,5 mg aliyense. Ndimamva bwino. Kulemera kunayamba kuchepa. Shuga panthawi yovomerezeka imasungidwa mkati mwa malire wamba. Sindikumvanso kuti ndili ndi mphamvu yodzichitira pandekha, koma posachedwapa miyendo yanga yayamba kuvulala kwambiri. ”

“Kwa zaka zoposa 10, ndakhala ndikudwala matenda ashuga a 2. Ndimatenga Glformin Prolong yamapiritsi awiri patsiku monga momwe adanenera adotolo miyezi iwiri. Mwambiri, ndimamva bwino, ngakhale nthawi zina pamakhala zovuta zamagaya ndi kusowa kudya. Mchimwene wanga amakhalanso ndi matenda a shuga, koma amadwala kapamba. Mankhwalawa sanamuyenerere. Mwambiri, ngati pali zolakwika zilizonse mu ntchito ya impso, ndikulimbikitsa kugwiritsa ntchito fanizo. Zimakhudza kwambiri ntchito yawo. "

Tatyana, wazaka 23.

"Sindikudwala matenda ashuga, ndidaganiza zomugwiritsa ntchito ngati Gliformin ngati mankhwala ochepetsa thupi. Kupatsidwa chiphuphu ndi mafuta ake oyaka msanga. Kulemera kunayamba kuchepa mwachangu, koma nthawi yomweyo kusanza kwambiri komanso kutsegula m'mimba kunayamba. Sindikudziwa momwe odwala matenda ashuga alili, koma thupi langa linali loipa kwambiri. Mwambiri, mankhwalawa sioyenera kuonda. "

Matenda a shuga ndi matenda omwe amakhala ndi chiwopsezo chachikulu kwambiri kuposa momwe angawonekere poyamba. Mankhwala Glyformin athandizira kuchepetsa zovuta zoyipa za matendawa. Komabe, musanagwiritse ntchito mankhwalawa ku chithandizo chamankhwala, funsani omwe amakuthandizani pazaumoyo. Kudzichitira nokha mankhwala a shuga kungakhale pachiwopsezo cha moyo. Dzisamalire nokha ndikukhala wathanzi!

Kukopera zinthu zapa masamba ndizotheka popanda chilolezo choyambirira

kukhazikitsa cholumikizira chokhazikika cha tsamba lathu.

Yang'anani! Zomwe zimasindikizidwa pamalopo ndizongodziwa zambiri komanso sizoyambitsa kugwiritsa ntchito. Onetsetsani kuti mwawonana ndi dokotala!

Zokhudza tsamba
Mafunso kwa katswiri
Zambiri
Kwa otsatsa
Pangano la ogwiritsa ntchito

Matenda a shuga ndi matenda oopsa omwe amakhala ndi zizindikiro zambiri zosasangalatsa. Wodwala amavutika kugona, kupweteka kwapawiri ndi ludzu. Muyeneranso kutsatira zakudya zovuta komanso masewera olimbitsa thupi. Koma pali nthawi zina pomwe izi sizokwanira ndipo thandizo lachipatala likufunika. Glformin Pronge ndi imodzi mwazomwe zimapangitsa kuti shuga azikhala ndi shuga. Ganizirani.

Kugwiritsa

Glyformin Pronge amalimbikitsa kugwiritsidwa ntchito kwa glucose ndi minofu, amachepetsa kuyamwa kwa matumbo m'matumbo. Komanso, mankhwalawa amathandizira chidwi cha zimakhala kuti insulin.

Zizindikiro zazikulu zogwiritsa ntchito mankhwalawa:

Type 2 shuga mellitus. Amagwiritsidwa ntchito ngati chakudya kapena zolimbitsa thupi sizinabweretse zotsatira zomwe mukufuna.
Mtundu woyamba wa shuga. Ntchito ngati cholumikizira insulin.

Kwa monotherapy. Gwiritsani ntchito ndi mankhwala ena omwe ali ndi vuto lofananalo kuloledwa.

Mankhwalawa saloledwa kugwiritsidwa ntchito popanda kupimidwa kuchipatala: Malangizo a glyformin ogwiritsira ntchito akuwonetsa zingapo zotsutsana.

Chithandizo cha Gliformin ndichitali. Pa mankhwala, muyenera kumachita mayeso omwe akuwonetsa zomwe zikuchitika pakhungu ndi impso. Asanakhale mayeso, muyenera kusiya kumwa mankhwalawa kwa maola osachepera 48. Ngati simutsatira lamuloli, ndiye kuti zotsatira zoyesa zingakhale zolakwika. Mankhwala amaloledwa kuyambiranso masiku angapo pambuyo pa njirazi.

Saloledwa kumwa mowa wambiri panthawi ya chithandizo. Muyeneranso kupewa mankhwala okhala ndi Mowa.

Komanso, maphunziro sanachitidwe kwa ana osakwana zaka 18. Munthawi imeneyi, mankhwalawa amayenera kumwedwa mosamala, motsogozedwa ndi achipatala mosalekeza.

Kutalika kwa Glyformin sikulimbikitsidwa kuti muchepetse thupi, kupatula kukayikira kuti apange shuga.

Zotsatira zoyipa

Mankhwala amatha kuyambitsa mavuto ena, kuwaganizira m'magulu:

Matenda a metabolism. Lactic acidosis imatha kuchitika, yomwe imafuna kuleka kwa mankhwala. Ngati mankhwalawa amamwa kwa nthawi yayitali, ndiye kuti pamakhala mavuto chifukwa cha mayamwidwe ake m'thupi.

Mavuto mu kayendedwe ka magazi. Nthawi zina, megaloblastic anemia imatha kuonedwa.

Zotsatira zoyipa zomwe zimakhudzana ndi zotupa pakhungu zimathanso kuchitika. Mwa iwo, zotupa ndi redness zimasiyanitsidwa.

Ngati panali zovuta zilizonse, ndiye kuti muyenera kuchepetsa mlingo wa mankhwalawa. Nthawi zina, kuchedwetsa nthawi yoikidwiratu ndi adokotala.

Ngati wodwala samva bwino, ndikofunikira kuyimbira ambulansi nthawi yomweyo. Kudzipatsa nokha sikuloledwa.

Mtengo wake ndi wa mapiritsi 60 a Glformin, kutengera zomwe alipo:

Glformin Prolong 1000 mg itenga ma ruble 479.

M'masitolo osiyanasiyana, mtengo ungasiyane pang'ono.

Ganizirani izi:

Glucophage. Muli ndi metformin. Simalimbikitsa katemera wa insulin. Kuchepetsa zomwe zili mumwazi m'magazi a anthu. Mtengo wa mapiritsi 30 ndi 500 mg.
Glucophage Kutalika. Pafupifupi chimodzimodzi ndi mankhwala am'mbuyomu. Amadziwika ndi kukhalapo kwa nthawi yayitali (kumasulidwa pang'onopang'ono kwa chinthu). Mtengo wa mapiritsi 60 a 500 mg ndi ma ruble 452.
Metformin. Sisintha zomwe zili mu insulin m'magazi. Kuchulukitsa shuga. Nthawi zambiri pamafunsidwa kuti ndi ndani Glitterin kapena Metformin amene amaposa. Mankhwala onse awiriwa ali ndi chinthu chimodzi chogwira ntchito komanso mfundo yothandizira, koma mtengo wotsirizira ndi wotsika - 103 ma ruble. mapiritsi 60 a 500 mg.
Fomu. Amakulitsa kuyamwa kwamatumbo. Kuchulukitsa chidwi cha insulin receptor. Zomwe zimagwiritsidwa ntchito ndi metformin. Formmetin imapamwamba kuposa mitundu ina, - 92 ma ruble. mapiritsi 60 a 500 mg.
Siofor. Imathandizira kugwiritsa ntchito shuga. Amachotseredwa osasintha kuchokera m'thupi. Siofor ndi wofanana ndi Gliformin pamalingaliro. Mtengo muma pharmacies ndi ma ruble 255. mapiritsi 60 a 500 mg.

Ma Analogs amakhala ndi manambala ake osalemba nawo malangizowa. Kusintha kuchokera ku mankhwala kupita kwina kuyenera kuchitika mosamala. Musanagwiritse ntchito, ndikofunikira kufunsa dokotala.

Ndemanga za "Gliformin (mapiritsi)" kuchokera kwa madokotala ndi odwala:

Zambiri zimapezeka patsambalo kuti mudziwe zokhazo. Onetsetsani kuti mukumane ndi katswiri.

Ngati mukuwona cholakwika m'lembalo, kuwunika kolakwika kapena chidziwitso cholakwika pofotokozedwaku, tikukupemphani kuti muwadziwitse woyang'anira tsamba lanu.

Ndemanga zomwe zalembedwa patsamba lino ndizomwe anthu omwe adalemba. Osadzisilira!

Gliformin: malangizo ogwiritsa ntchito ndi kuwunikira

Dzina lachi Latin: Gliformin

Code ya ATX: A10BA02

Chithandizo chogwira: metformin (metformin)

Wopanga: JSC Akrikhin (Russia)

Kusintha malongosoledwe ndi chithunzi: 10.20.2017

Mitengo muma pharmacies: kuchokera ku ma ruble a 106.

Gliformin ndi wothandizira pakamwa wa hypoglycemic.

Kutulutsa mawonekedwe ndi kapangidwe kake

Mlingo wa Glformin:

Mapale: flat-cylindrical okhala ndi mzere wogawika ndi chamfer, oyera kapena oyera (zidutswa 10 chilichonse m'matumba a chithuza, mapaketi 6 m'bokosi la makatoni),
Mapiritsi okhala ndi filimu: yoyera kapena yoyera yokhala ndi imvi kapena zonona zonona, biconvex, mawonekedwe ozungulira (ma PC 60. M'matumba a polyethylene kapena polypropylene, mu bokosi la makatoni 1 amatha).

Chosakaniza chophatikizika ndi metformin hydrochloride:

Piritsi 1 - 0,5 g
Piritsi limodzi mu utoto wa film - 0,85 g kapena 1 g.

Mapiritsi: calcium stearate kapena stearic acid, sorbitol, povidone (polyvinylpyrrolidone), calcium phosphate dihydrate, macrogol (polyethylene glycol),
Mapiritsi okhala ndi filimu: povidone, wowuma wa mbatata, stearic acid.

Zomwe zimapangidwa ndi nembanemba wa kanema: macrogol (polyethylene glycol 6000), hypromellose (hydroxypropyl methylcellulose), talc.

Pharmacokinetics

Pambuyo pakukonzekera pakamwa, metformin imatengedwa kuchokera m'matumbo am'mimba kwathunthu. Mtheradi wake wa bioavailability umafika 50-60%. Kuchuluka kwazinthu zambiri m'madzi a m'magazi zimafika pafupifupi maola 2,5 pambuyo pa kukhazikitsa ndipo ndi 15 μmol, kapena 2 μg / ml. Mukamamwa metformin ndi chakudya, mayamwidwe ake amachepetsa ndikuchepetsa. Imafalitsidwa mwachangu m'thupi lonse, osagwirizanitsa ndi mapuloteni a plasma.

Metformin imapangidwa pang'ono ndipo imatulutsidwa mkodzo. Chilolezo chake mwa odzipereka athanzi ndi 400 ml / min (omwe ali okwanira 4 kuposa creatinine chilolezo), chomwe chimatsimikizira kukhalapo kwa katulutsidwe kazikulu kakang'ono. Hafu ya moyo ndi pafupifupi maola 6.5. Ndi kulephera kwa aimpso, zimachulukana, zomwe zimayambitsa chiopsezo cha kukopeka kwa mankhwalawa.

Malangizo ogwiritsira ntchito Glformin: njira ndi mlingo

Mapiritsi a Glyformin amatengedwa pakamwa pakudya kapena akangomaliza, osatafuna, ndi madzi ambiri.

Dokotalayo amapereka mankhwala ndi nthawi ya makonzedwe payekhapayekha, poganizira kuchuluka kwa shuga m'magazi.

Kumayambiriro kwa chithandizo, woyamba, mlingo umatha kukhala 0,5 mpaka 1 g kamodzi patsiku, ndiye, kutengera kuchuluka kwa shuga m'magazi, utha kuwonjezeka pang'onopang'ono. Mlingo wokonza, monga lamulo, ndi 1.5-2 g patsiku, wogawika mu waukulu Mlingo wa 2-3.

Mlingo wambiri watsiku ndi tsiku wa Glformin ndi 3 g.

Kwa odwala okalamba, muyeso wovomerezeka wa mankhwalawa ndi 1 g patsiku.

Pankhani ya kusokonezeka kwakukulu kwa metabolic, mlingo umalimbikitsidwa kuti uchepe, chifukwa chiopsezo cha lactic acidosis chikuwonjezeka.

Zotsatira zoyipa

Kuchokera endocrine dongosolo: vuto la bongo - hypoglycemia,
Kuchokera mmimba: kuperewera kwa chakudya, kupweteka kwam'mimba, kusanza, kutsekemera kwazitsulo mkamwa, kutsekula m'mimba, kusanza, kusilira (zizindikirazi ndi njira zoyambira kuchitira chithandizo, kenako mkhalidwe umasintha).
Kuchokera ku hemopoietic dongosolo: nthawi zina - megaloblastic anemia,
Kuchokera kumbali ya kagayidwe: ndi chithandizo chokhalitsa - hypovitaminosis B₁₂, nthawi zina, lactic acidosis,
Thupi lawo siligwirizana: zotupa pakhungu.

Ngati zotsatira zoyipa zimachitika, ndikofunikira kusiya Glyformin kwakanthawi ndikuyang'ana kwa dokotala.

Malangizo apadera

Kuchiza kuyenera kutsagana ndi kuwunika pafupipafupi kuchuluka kwa shuga m'magazi.

Munthawi yamankhwala, maphunziro akuyenera kuchitika miyezi isanu ndi umodzi iliyonse kuti adziwe kuchuluka kwa lactate ndi creatinine m'madzi a m'magazi. Ntchito ya impso imayang'aniridwa mosamala makamaka kwa okalamba. Glyformin sayenera kulembedwa kwa amuna omwe ali ndi mtundu wa creatinine wapamwamba 135 μmol / L, kwa akazi - 110 μmol / L.

Zotsatira zoyipa za m'mimba zitha kuchepetsedwa pogwiritsa ntchito antacid kapena antispasmodics.

Pa mankhwala ayenera kupewa mowa ndi mankhwala okhala Mowa.

Ndi monotherapy, Glformin sikukhudza kuyendetsa magalimoto ndi kugwira ntchito ndi makina.

Pomwe mukutenga Glformin ndi othandizira ena a hypoglycemic, kuphatikizapo insulin, sulfonylureas, ndikofunikira kusamala poyendetsa magalimoto ndikuchita zinthu zoopsa zomwe zimafuna kuthamanga kwa ma psychomotor komanso kuwonetsa chidwi.

Kuyanjana kwa mankhwala osokoneza bongo

Ndikotheka kuwonjezera zomwe Glyformin amagwiritsa ntchito munthawi yomweyo ndi insulin, beta-blockers, sulfonylureas, non-steroidal anti-yotupa, acarbose, monoamine oxidase inhibitors, angiotensin kutembenuza ma enzyme, oxytetracycline, cyclophosphamide, ndi ena.

Zotsatira za Gliformin zitha kuchepetsedwa pogwiritsa ntchito glucagon, glucocorticosteroids, njira zakulera pakamwa, mahomoni a chithokomiro, epinephrine, sympathomimetics, "loop" ndi thiazide diuretics, zotumphukira za nicotinic acid ndi phenothiazine.

Kugwiritsa ntchito pamodzi kwa mankhwala okhala ndi ethanol kumatha kuyambitsa lactic acidosis.

Kuwonongeka kwa Glyformin kumachepetsedwa ndikaphatikizidwa ndi cimetidine, mwayi wopanga lactic acidosis ukuwonjezeka.

Ndi munthawi yomweyo makonzedwe anticoagulants, coumarin zotumphukira, zotsatira zawo amachepetsa.

Mafanizo a Gliformin ndi awa: Glucofage, Glucofage Long, Glukoran, Gliguanid, Dformin, Diaberit, Diabetesosan, Diabexil, Diguanil, Metformin, Melbin, Mellitin, Metiguanid, Modulan, Formmetin.

Mtengo wa Gliformin m'masitolo ogulitsa mankhwala

Mtengo woyenerera wa mapiritsi a Glformin 0,5 g m'matangadza a pharmacy ndi ma ruble 86-130 (phukusi lili ndi mapiritsi 60). Mutha kugula mapiritsi mu filimu yamafuta omwe ali ndi mulingo wa 0,85 ga kwa ma ruble 191-217, ndi mlingo wa 1 g wa ma ruble 242-329 (phukusi lirilonse lili ndi mapiritsi 60).

Mapiritsi a Gliformin 500mg No. 60

Gliformin 500 mg n60 tabu

Mapiritsi a Gliformin 500 mg 60 ma PC.

Gliformin Tab. 500mg n60

Gliformin Tab. p.p.o. 850mg n60

Glformin Pronge Tab. pitilizani. cholemba. n / ogwidwa. 750mg No. 30

Mapiritsi a Gliformin 60 ma PC.

Maphunziro: Rostov State Medical University, apadera "General Medicine".

Zambiri zokhudzana ndi mankhwalawa ndizofanana, zimaperekedwa pazidziwitso ndipo sizilowa m'malo mwa malangizo ovomerezeka. Kudzipatsa nokha mankhwala kuopsa!

Malinga ndi asayansi ambiri, mavitamini zovuta ndizothandiza kwa anthu.

Okonda akapsopsona, aliyense wa iwo amataya 6.4 kcal pamphindi, koma nthawi yomweyo amasinthana mitundu pafupifupi 300 ya mabakiteriya osiyanasiyana.

Pochezera pafupipafupi pakama pofufuta, mwayi wokhala ndi khansa yapakhungu umawonjezeka ndi 60%.

Mankhwala ambiri poyamba anali ogulitsidwa ngati mankhwala osokoneza bongo. Mwachitsanzo, a heroin adagulitsidwa ngati mankhwala a chifuwa. Ndipo cocaine adalimbikitsidwa ndi madokotala ngati opaleshoni komanso ngati njira yowonjezerera kupirira.

Poyesera kuti wodwalayo atuluke, madokotala nthawi zambiri amapita kutali kwambiri. Ndiye, mwachitsanzo, Charles Jensen wina mzaka kuyambira 1954 mpaka 1994. adapulumuka ntchito zopitilira 900 neoplasm.

Ntchito yomwe munthu samakonda imakhala yovulaza psyche yake kuposa kusowa kwa ntchito konse.

Asayansi ochokera ku Yunivesite ya Oxford adachita maphunziro angapo, pomwe adazindikira kuti zamasamba zimatha kukhala zovulaza ku ubongo wa munthu, chifukwa zimapangitsa kuchepa kwa unyinji wake. Chifukwa chake, asayansi amalimbikitsa kuti asachotsere konse nsomba ndi nyama muzakudya zawo.

Pa moyo, munthu wamba amapanga miyala yocheperako yoposa awiri.

Munthu amene amamwa mankhwala opondeleza nthawi zambiri amakhalanso ndi nkhawa. Ngati munthu athana ndi kukhumudwa paokha, ali ndi mwayi wonse wakuyiwalako zamtunduwu mpaka kalekale.

Kuphatikiza pa anthu, cholengedwa chimodzi chokha padziko lapansi - agalu, omwe ali ndi vuto la prostatitis. Awa ndi abwenzi athu okhulupilika kwambiri.

Mankhwala odziwika bwino "Viagra" adapangidwa kuti azichitira matenda oopsa.

Malinga ndi kafukufuku wa WHO, kuyankhulana kwa theka la ola limodzi pafoni kumawonjezera mwayi wokhala ndi chotupa muubongo ndi 40%.

Chiwindi ndi chiwalo cholemera kwambiri m'thupi lathu. Kulemera kwake pafupifupi 1.5 kg.

Ngati mumamwetulira kawiri kokha patsiku, mutha kutsitsa magazi ndikuchepetsa chiopsezo cha matenda a mtima ndi stroko.

Mwazi wa munthu "umayenda" m'matumbo omwe akukakamizidwa kwambiri, ndipo ngati umphumphu wake waphwanyidwa, amatha kuwombera mpaka 10 metres.

Kuvulala kwa cholesterol yokwera "yayitali" ndikuwonekeranso kwa thupi.Zatsimikiziridwa kale kuti izi zimatsogolera ku atherosulinosis ndipo, chifukwa chake, zimawonjezera ngozi.

Mapiritsi yoyera kapena pafupifupi yoyera, yosalala, yokhala ndi bevel ndi notch.

Omwe amathandizira: sorbitol, calcium phosphate dihydrate, povidone (polyvinylpyrrolidone), macrogol (polyethylene glycol), calcium stearate kapena stearic acid.

Ma PC 10 - matumba a matuza (6) - mapaketi a makatoni.

Mapiritsi okhala ndi mafilimu yoyera kapena yoyera yokhala ndi zonona kapena zotuwa, zotayirira, biconvex.

Omwe amathandizira: wowuma wa mbatata, povidone (polyvinylpyrrolidone), stearic acid.

Zomwe zimapangidwa ndi chipolopolo: hypromellose (hydroxypropyl methylcellulose), macrogol (polyethylene glycol 6000), talc.

Ma PC 60. - zitini za polypropylene (1) - mapaketi a makatoni.

Ma PC 60. - zitini za polyethylene (1) - mapaketi a makatoni.

Mapiritsi okhala ndi mafilimu yoyera kapena yoyera yokhala ndi zonona kapena zotuwa, zotayirira, biconvex.

Omwe amathandizira: wowuma wa mbatata, povidone (polyvinylpyrrolidone), stearic acid.

Zomwe zimapangidwa ndi chipolopolo: hypromellose (hydroxypropyl methylcellulose), macrogol (polyethylene glycol 6000), talc.

Ma PC 60. - zitini za polypropylene (1) - mapaketi a makatoni.

Ma PC 60. - zitini za polyethylene (1) - mapaketi a makatoni.

Hypoglycemic mankhwala othandizira pakamwa kuchokera pagulu la Biguanides. Glyformin imalepheretsa gluconeogenesis m'chiwindi, amachepetsa kuyamwa kwa m'matumbo, imakulitsa kugwiritsidwa ntchito kwa glucose, komanso kumakulitsa chidwi cha minofu kulowa insulin. Komabe, sizikhudza kubisika kwa insulini ndi ma cell a beta a kapamba. Amachepetsa mulingo wa triglycerides ndi LDL m'magazi. Imakhazikika kapena kuchepetsa thupi. Ili ndi fibrinolytic mwina chifukwa chokakamira minofu ya plasminogen activator inhibitor.

Mutatha kumwa mankhwalawo mkati, metformin imayamwa kuchokera m'mimba. C_max metformin mu plasma imatheka pambuyo 2-2.5 maola atatha kumwa muyezo, bioavailability ndi 50-60%.

Sizikugwirizana ndi mapuloteni a plasma. Amadziunjikira mu ndulu zakumaso, chiwindi ndi impso.

T_1/2 ndi maola 1.5-4,5. Imapukutidwa osasinthika ndi impso.

Pharmacokinetics mu milandu yapadera yamankhwala

Ndi matenda aimpso, kuwonongeka kwa mankhwalawa ndikotheka.

- lembani matenda ashuga a 2 omwe amachititsa kuti asamamwe komanso azigwira bwino ntchito pakudya (makamaka odwala omwe ali ndi kunenepa kwambiri) monga monotherapy kapena kuphatikiza mankhwala ena a hypoglycemic.

- matenda a shuga, chikomokere,

- kuwonongeka kwaimpso,

- Matenda owopsa omwe amabwera chifukwa cha kuwonongeka kwa impso: kuchepa magazi (ndi m'mimba, kusanza), kutentha thupi, matenda opatsirana, hypoxia (mantha, sepsis, matenda a impso, matenda a bronchopulmonary),

- mawonetseredwe azachipatala owonetsa matenda opweteka kwambiri komanso osachiritsika omwe angayambitse kukula kwa minofu hypoxia (kuphatikizapo mtima kapena kupuma, kulephera kwa myocardial infarction, ngozi ya pachimake ya ubongo),

- opaleshoni yayikulu ndikuvulaza mukasonyezedwa chithandizo cha insulin,

- chiwindi ntchito,

- uchidakwa wambiri, chakumwa choledzeretsa chachikulu,

- lactic acidosis (kuphatikizapo mbiri),

- gwiritsani ntchito kwa masiku osachepera a 2 musanadutse masiku awiri mutapanga maphunziro a radioisotope kapena x-ray ndikukhazikitsa ma iodine okhala ndi zosiyana pakati,

- kutsatira zakudya zochepa zopatsa mphamvu (zosakwana 1000 cal / tsiku),

- mkaka wa m'mawere (yoyamwitsa),

- Hypersensitivity ku zigawo za mankhwala.

Sitikulimbikitsidwa kugwiritsa ntchito mankhwalawa odwala omwe ali ndi zaka zopitilira 60 omwe amagwira ntchito yolemetsa, yomwe imalumikizidwa ndi chiwopsezo chokhala ndi lactic acidosis mwa iwo.

Mlingo wa mankhwalawa umayikidwa ndi dokotala payekha, kutengera kuchuluka kwa shuga m'magazi.

Mlingo woyambirira ndi 0.5-1 g / tsiku kapena 0,85 g 1 nthawi / tsiku. Kuwonjezeka kwapang'onopang'ono kwa mlingo kumatheka kutengera mtundu wa glycemia. Mankhwala okonza mankhwalawa nthawi zambiri amakhala 1.5-2 g / tsiku. Mulingo waukulu ndi 3 g / tsiku. Kuti muchepetse kusokonezeka kwa dongosolo logaya chakudya, tsiku lililonse mutha kugawa magawo awiri.

Odwala okalamba, tsiku lililonse mankhwala sayenera kupitirira 1 g.

Pazovuta zazikulu za metabolic, mlingo wa mankhwala Glyformin uyenera kuchepetsedwa chifukwa chowonjezera chiopsezo cha lactic acidosis.

Mapiritsi a Glyformin amayenera kumwedwa popanda kutafuna, nthawi yakudya kapena itangotha, kumwa madzi ambiri.

Kuchokera m'mimba: nseru, kusanza, kulumikizana kwachitsulo mkamwa, kusowa chilakolako cha chakudya, kutsegula m'mimba, kusilira, kupweteka kwam'mimba. Zizindikirozi ndizofala kumayambiriro kwa chithandizo ndipo nthawi zambiri zimakhala zokha. Zizindikiro izi zitha kuchepetsedwa ndikulemba antacid, atropine derivatives kapena antispasmodics.

Kuchokera kumbali ya kagayidwe: Nthawi zina - lactic acidosis (amafuna discontinuation chithandizo), ndi chithandizo cha nthawi yayitali - hypovitaminosis B₁₂ (malabsorption).

Kuchokera ku hemopoietic system: Nthawi zina - megaloblastic anemia.

Kuchokera ku endocrine system: hypoglycemia (mukamagwiritsa ntchito mankhwala osayenera).

Zotsatira zoyipa: zotupa pakhungu.

Pazifukwa zoyipa, mankhwalawa amayenera kuchepetsedwa kapena kusiyidwa kwakanthawi.

Zizindikiro lactic acidosis imayamba. Zomwe zimayambitsa kukula kwa lactic acidosis amathanso kukhala cumulation wa mankhwalawa chifukwa cha kuwonongeka kwa aimpso. Zizindikiro zoyambirira za lactic acidosis ndizofooka zambiri, nseru, kusanza, kutsegula m'mimba, kutsitsa kutentha kwa thupi, kupweteka kwam'mimba, kupweteka kwa minofu, kuchepa kwa magazi, kuperewera kwa bradyarrhythmia, mtsogolo kungakhale kupuma kwambiri, chizungulire, chikumbumtima chodwala komanso kukula kwa chikomokere.

Chithandizo: vuto la lactic acidosis, chithandizo ndi Glformin ziyenera kuyimitsidwa nthawi yomweyo, wodwalayo ayenera kuchipatala mwachangu ndipo, atatsimikiza kuti ali ndi lactate, atsimikizire kuti ali ndi matendawa. Njira yothandiza kwambiri yochotsa lactate ndi metformin kuchokera mthupi ndi hemodialysis. Chithandizo cha Zizindikiro zimachitidwanso.

Ndi munthawi yomweyo kugwiritsa ntchito mankhwala a sulfonylurea, acarbose, insulin, NSAIDs, ma inhibitors a MAO, oxytetracycline, ACE inhibitors, clofibrate zotumphukira, cyclophosphamide, beta-blockers, ndizotheka kupititsa patsogolo zotsatira za hypoglycemic ya mankhwala a Glyformin.

Pogwiritsa ntchito munthawi yomweyo mankhwala a corticosteroids, mankhwala opatsirana pakamwa, epinephrine, sympathomimetics, glucagon, chithokomiro cha chithokomiro, thiazide ndi "loop" diuretics, zotumphukira za phenothiazine, zotumphukira za nicotinic, zotheka kuchepetsa zotsatira za hypoglycemic ya mankhwala a Glyformin.

Cimetidine amachepetsa kuchotsedwa kwa mankhwalawa Glyformin, chifukwa chomwe chiopsezo chokhala ndi lactic acidosis chikuwonjezeka.

Gliformin amatha kufooketsa mphamvu ya ma anticoagulants (zotumphukira za coumarin).

Ndi kumwa kwa nthawi yomweyo ethanol, lactic acidosis imayamba.

Mankhwalawa, ntchito ya impso iyenera kuyang'aniridwa: kamodzi pa miyezi isanu ndi umodzi, chiwongolero cha serum creatinine ndikofunikira (makamaka kwa odwala okalamba). Glformin sayenera kufotokozedwa ngati mulingo wa serum creatinine m'magazi ndiwoposa 135 μmol / L mwa amuna ndi 110 μmol / L mwa akazi.

Osachepera 2 pachaka, komanso maonekedwe a myalgia, zomwe zimakhala mu plasma ziyenera kutsimikiziridwa.

Maola 48 asanafike komanso mkati mwa maola 48 mutatha kuphunzira mwatsatanetsatane wa X-ray (urography, iv angiography), muyenera kusiya kumwa Glyformin.

Pa chithandizo, muyenera kupewa kumwa mowa ndi mankhwala okhala ndi Mowa.

Glyformin itha kugwiritsidwa ntchito limodzi ndi zotumphukira za sulfonylurea. Potere, makamaka kuyang'anira kuchuluka kwa shuga m'magazi ndikofunikira.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Akagwiritsidwa ntchito ngati monotherapy, Glyformin sasokoneza kuthekera koyendetsa magalimoto ndi kugwira ntchito ndi makina. Glformin ikaphatikizidwa ndi ma othandizira ena a hypoglycemic (kuphatikizapo sulfonylurea, insulin), mikhalidwe ya hypoglycemic imatha kukhala ndi kuthekera kochita kuyendetsa magalimoto ndi kuchita zina zomwe zingakhale zoopsa zomwe zimafunikira chidwi chochulukirapo komanso kugwiritsidwa ntchito kwakanthawi kwa psychomotor.

Gwiritsani ntchito pa nthawi yoyembekezera komanso nthawi yoyamwitsa (yoyamwitsa) ndi contraindified.

Pokonzekera kutenga pakati, komanso ngati muli ndi pakati mukamamwa Glformin, mankhwalawa ayenera kusiyidwa ndipo mankhwala a insulin ayenera kuyikidwa.

Sizikudziwika ngati metformin yachotsedwa mkaka wa m'mawere, chifukwa chake, glformin imaphatikizidwa pakamayamwa. Ngati mukufunika kugwiritsa ntchito mankhwala Glyformin pa mkaka wa m`mawere, kuyamwitsa kuyenera kuyimitsidwa.

Sitikulimbikitsidwa kugwiritsa ntchito mankhwalawa odwala omwe ali ndi zaka zopitilira 60 omwe amagwira ntchito yolemetsa, yomwe imalumikizidwa ndi chiwopsezo chokhala ndi lactic acidosis mwa iwo. Odwala okalamba, tsiku lililonse mankhwala sayenera kupitirira 1 g.

Mndandanda B. Mankhwalawa amayenera kusungidwa kuti asawonekere ana, m'malo owuma, amdima pamtunda wosaposa 25 ° C. Alumali moyo mapiritsi a 500 mg ndi zaka zitatu, mapiritsi a 850 mg ndi 1 g - 2 years.

Kuti mufunse funso lokhudza ntchito ya polojekiti kapena kulumikizana ndi akonzi, gwiritsani ntchito mawonekedwe awa.

Malangizo ogwiritsira ntchito:

Mitengo muma pharmacie opezeka pa intaneti:

Gliformin ndi mankhwala osokoneza bongo a hypoglycemic.

Zotsatira zoyipa

Gliformin ndi amodzi mwa otetezeka kwambiri a hypoglycemic; mikhalidwe yambiri yosavutikira imangokhala yokha pakapita nthawi, popanda chithandizo chamankhwala. Kuti zotsatira zosayenerera sizisokonezeka, mlingo uyenera kusinthidwa pang'onopang'ono pamene thupi lazolowera kale zinthu zina.

Kwa Biguanides, mbali yayikulu ndi kuphwanya kwam'mimba

Zowopsa,
Kutsegula m'mimba
Kupanda chilimbikitso
Sinthani muma masamba a kukoma (mawonekedwe azitsulo).

Poyerekeza ndi gliformin mu matenda a shuga malinga ndi malingaliro, ndiye kuti nthawi yosinthira imatenga milungu iwiri. Kuletsa glucose m'matumbo kumayendera limodzi ndi kupesa komanso kumasulidwa kwa kaboni dayokisaidi. Chifukwa chake madandaulo a bata, kufalikira, kutsegula m'mimba.

Ngati vuto la dyspeptic limayendera limodzi ndi kupweteka kwa epigastric ndipo silikuchoka pakatha mwezi umodzi, mutha kuyesa kuchepetsa mlingo kapena kubwezeretsa generic yokhala ndi French French Glucophage, kapangidwe kake, kuphatikizapo zinthu zowonjezera metformin, zaphunziridwa kwa zaka 10.

Mawonekedwe a mziwopsezo mu mawonekedwe a erythema, zotupa, kuyabwa kwa khungu ndizosowa, koma m'malo mwake mankhwalawa nthawi zambiri amasinthidwa. Hypoglycemia imatheka pokhapokha ngati pali mitundu yovuta ya mankhwala, yokhala ndi mankhwala osokoneza bongo ambiri, kuperewera kwa zakudya m'thupi, kugwira ntchito molimbika.

Ndani safanane ndi Gliformin

Mndandanda wa contraindication pamankhwala onse otengera metformin ndiofala. Kuphatikiza pa kulephera kwa impso, kuchulukitsa koopsa kwa zinthu zowola zomwe zimayambitsa kuledzera, mankhwalawa sanalembedwe kuti:

Matenda a shuga
Njira zazikulu za hepatic,
Zowonongeka zaposachedwa,
Hypersensitivity pazomwe zimapangidwira,
Mimba ndi kuyamwitsa (gulu ili la anthu odwala matenda ashuga ayenera kukhala pa insulin)
Matenda a shuga kwa ana osaposa zaka 10 - palibe umboni wa kuchita bwino ndi chitetezo,
M'mikhalidwe yowopsa yomwe imayambitsa lactic acidosis.

Kudzikundikira kwa lactic acid (harbinger wa lactic acidosis) kumathandizidwa ndi kukanika kwa impso, kumwa mowa mwauchidakwa, matenda omwe amachititsa kupuma kukhala kovuta kwa minofu (matenda, matenda amtima, mapapu am'mimba), matenda ashuga ketoacidosis, kuchepa kwa madzi m'mimba ndi matenda am'mimba, kutentha thupi komanso kusanza. Mpaka homeostasis itatha kubwezeretsedwa kwathunthu, Glyformin amachotsedwa mu zochitika zonse.

Pa opaleshoni, ndi kuvulala kwambiri, matenda opatsirana, maphunziro a radiopaque, metformin imasinthidwa kwa masiku angapo ndikukonzekera insulin.

Ndi chakudya choperewera, chakudya cham'mimba, pomwe wodwala amalandila zosakwana 1000 kcal / tsiku, masupuni amthupi. Matendawa ndi owopsa chifukwa cha metabolic ketoacidosis.

Zotsatira Zogwiritsa Ntchito Mankhwala

Kuchepetsa kwa mphamvu ya hypoglycemic komwe Glyformin angakule ndikugwiritsira ntchito munthawi yomweyo insulin, NSAIDs, mankhwala a sulfa-urea, ndi β-blockers.

Zoletsa za ntchito ya metformin zimatha kukhala glucocorticosteroids, njira zakulera zamlomo, mahomoni a chithokomiro, zotumphukira za nicotinic acid, thiazide diuretics.

Mtengo ndi kusungirako kwa mankhwalawo

Kusunga kwa Glyformin mikhalidwe yapadera sikofunikira: zoyambira zoyambirira, kutentha kwa mpaka 25 ° C, malo otetezedwa ku radiation ya ultraviolet ndi ana. Wopanga amawerengera mapiritsi a chipolopolo nthawi yotsimikizira ya zaka ziwiri, popanda iwo - zaka zitatu. Pamapeto pa moyo wake wa alumali, mankhwalawo amayenera kutayidwa.

Ku Gliformin, mtengo wa ambiri ndi wotsika mtengo:paketi yamapiritsi mu kanema yoteteza ingagulidwe ma ruble 300, popanda iyo - ma ruble 150. (Mlingo wa metformin ndi 0,5 mg).

Momwe mungasinthire glformin

Pakhoza kukhala zifukwa zambiri zosinthira mankhwalawa - kuchokera pamwayi wazachuma mpaka pakusalozeka kwapadera, koma mulimonse, dokotala ayenera kusankha fanizo la Gliformin kutengera momwe wodwalayo akuwunikira komanso kukhala bwino. Pokambirana, muyenera kufotokoza mwatsatanetsatane za zoyipa zomwe zimachitika, komanso lembani mankhwala onse omwe mumamwa limodzi.

Kuchokera pagulu la ma biagunides, ndi mankhwala amodzi okha omwe amagwiritsidwa ntchito mwachangu - metformin, pakati pa zida za Glyformin zomwe zimagwiritsidwa ntchito zomwe zimadziwika kwambiri:

Vuto la kuchepa thupi limada nkhawa 23% ya anthu. Chikhumbo chofuna kukhala ndi nsanje komanso kusirira, yesetsani kusonkhanitsa mafashoni atsopano osadzikuta m'matumba opanda mawonekedwe kumapangitsa atsikana kukhala pachiwopsezo chathanzi lawo osaganizira kwenikweni za zotsatirapo zake. Kodi metformin imagwira ntchito bwanji pamenepa?

Malinga ndi madokotala, kunenepa kwambiri, kukana insulini kulipo. Ngati khungu litatsekedwa ndi kapisozi wamafuta, chidwi cha zolandirazo chimatsika ndipo glucose sawafikira. Zikondazo zimathandizira kupanga insulini, kudziunjikira kowonjezera kumakhala ndi vuto loyipa la mafuta.

Chimodzi mwa zifukwa zazikuluzikulu zothandizira kukana insulini ndizakudya zopanda thanzi zomwe zimakhala ndi chakudya chambiri champhamvu kwambiri. Ngati insulin yosagwira ntchito kwambiri imakhala yosasangalatsa kwa iye. Zotsatira zake ndi kunenepa kwambiri, hyperinsulinism. Mankhwalawa amabwezeretsa tinthu timene timagwira ntchito, ndipo glucose akamakoka nthawi zambiri, ndiye kuti mafutawo samakula.

Gliformin: malangizo ogwiritsira ntchito kuchepa thupi

Ngati mwatsimikiza kuti muchepetse thupi ndi mapiritsi, muyenera kutero molondola. Kugula Gliformin silinali vuto, ngakhale kuti mankhwala onse a hypoglycemic amaperekedwa ngati mankhwala omwe mumalandira. Mukamawerenga malangizo, samalani kwambiri ndi contraindication ndi zovuta - kuchepa kwa magazi, gastritis, neuritis.

Yambitsani maphunzirowa ndi mlingo wocheperako (0,5 g), kutsatira zomwe zimawachitikira ndikusintha kwa thanzi. Mukayamba ndi Mlingo wina, zosangalatsa za zotsatira zoyipa (makamaka matenda ammimba) sizingakuthandizeni kudikirira.

Mapiritsi amagwiritsidwa ntchito musanadye kapena mutatha kudya, koma amathanso kugwiritsidwa ntchito usiku - izi sizikutsutsana ndi zomwe ali nazo. Pakupita milungu iwiri, mutha kuwunika momwe mungasinthire mlingowo mpaka 2 g / tsiku. kapena m'malo mankhwalawo.

Kuyerekeza kwa Gliformin ndi madokotala ndi odwala matenda ashuga

Madotolo amayesa njira zochizira za Glformin pogwiritsa ntchito luso lawo la insulin. Kugwiritsa ntchito Glformin kuti muchepetse kunenepa, ndikuwunika ndemanga za madokotala, ndizosathandiza.

Kuwona Katswiri pa Kuthekera kwa Glyformin ndi Madongosolo Ena a Metformin Polemera Kutaya - pavidiyoyi

Zotsatira za pharmacological

Glyformin ya matenda ashuga iyenera kumwedwa kokha pakamwa. Kapangidwe ka mankhwala pamakina a ziwalo zamkati sikumveka bwino.

Zilowa mthupi, chinthu chogwira ntchito chimakhala ndi zotsatirazi:

Kugwiritsa ntchito mankhwalawa "Glyformin" odwala matenda ashuga komanso kunenepa kwambiri kumapangitsa kuchepa kwa chikhumbo ndi thupi. Malangizowo akuwonetsa kuti mankhwalawa amalimbikitsa kusinthasintha pang'onopang'ono kwa kuwundana kwa magazi ndikuletsa kupendekera.

Metformin hydrochloride imalowa mwachangu ndi maselo am'mimba. Pazitali zantchito yogwira ntchito imakhazikika pambuyo pa maola awiri kuchokera panthawiyi. Yake bioavailability pafupifupi 50-60%. Mankhwalawa samakumana ndi mapuloteni a plasma, pang'onopang'ono amadziunjikira machitidwe a ziwalo zamkati. Kuchokera mthupi, thupilo limachotsedwako pafupifupi osasinthika.

Mlingo ndi makonzedwe

Mlingo wa Glformin umatsimikiziridwa ndi dokotala aliyense wodwala payekhapayekha, poganizira kuchuluka kwa shuga m'magazi, msinkhu komanso kuopsa kwa zisonyezo zamatenda.

Mlingo woyambirira ukhoza kukhala kuchokera ku 500 mg mpaka 1 gramu ya metformin. Imwani mankhwalawo kamodzi patsiku ndi zakudya kapena mukangodya. Kutengera mlingo wa glycemia pambuyo poyambira mankhwala, mlingo umatha kuwonjezeka pang'onopang'ono. Mlingo wokonza, monga lamulo, ndi magalamu 1.5-2 patsiku, mulingo wovomerezeka ndi 3. Kuti muchepetse zovuta kuchokera pamimba, njira ya tsiku ndi tsiku iyenera kugawidwa pawiri.

Okalamba salimbikitsidwa kupitilira muyeso wa 1 mg. Kuchepetsa kwa pafupifupi tsiku ndi tsiku kumafunikanso kwa odwala omwe ali ndi vuto lalikulu la metabolic, chifukwa ali ndi chiopsezo chowonjezereka cha lactic acidosis.

Migwirizano ndi magwiritsidwe akusungidwa

Sungani pamalo owuma, owuma bwino mpaka 25 ° C. Pewani kufikira ana.

Moyo wa alumali: mapiritsi - zaka 3, mapiritsi okhala ndi filimu - zaka 2.

Mankhwala Okhala Pamalo a Pharmacy

Yoperekedwa ndi mankhwala.

Ndemanga za Gliformin

Monga maumboni okhudzana ndi Gliformin amathandizira, makamaka pa matenda a shuga komanso pazovuta zosiyanasiyana za metabolic. Komanso, nthawi zambiri amagwiritsidwa ntchito ndi odwala omwe akufuna kuchepa thupi, ndipo anthu ena omwe adagwiritsa ntchito pazinthu izi amati anatha kuchepetsa thupi komanso kusintha matenthedwe a mahomoni. Komabe, akatswiri ambiri amachenjeza motsutsana ndi kugwiritsa ntchito Glformin kuti muchepetse thupi, ngati palibe umboni wowonetsa izi.

Odwala ena amatchula zotsatirapo zoyipa za mankhwalawa, kuphatikiza mutu, kufooka, matenda osokoneza bongo. Popeza amatha kupereka zotsatira zabwino komanso zoipa mthupi, tikulimbikitsidwa kulandira chithandizo mosamalidwa ndi dokotala.

Mtengo wa Gliformin m'masitolo ogulitsa mankhwala

Mtengo woyenerera wa mapiritsi a Glformin 0,5 g m'matangadza a pharmacy ndi ma ruble 86-130 (phukusi lili ndi mapiritsi 60).Mutha kugula mapiritsi mu filimu yamafuta omwe ali ndi mulingo wa 0,85 ga kwa ma ruble 191-217, ndi mlingo wa 1 g wa ma ruble 242-329 (phukusi lirilonse lili ndi mapiritsi 60).